PARVG

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: Members of the parvin family, including PARVG, are actin-binding proteins associated with focal contacts. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1antigen processing and presentation of endogenous peptide antigen (GO:0002483)5.87489905
2antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)5.87489905
3antigen processing and presentation of endogenous antigen (GO:0019883)5.38418291
4positive regulation of gamma-delta T cell activation (GO:0046645)4.97595291
5ribosomal small subunit assembly (GO:0000028)4.78398561
6detection of other organism (GO:0098543)4.53221611
7detection of bacterium (GO:0016045)4.45139784
8regulation of B cell receptor signaling pathway (GO:0050855)4.33409330
9positive regulation of B cell differentiation (GO:0045579)4.26749196
10positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)4.24991587
11macrophage activation involved in immune response (GO:0002281)4.20747290
12negative regulation of interleukin-12 production (GO:0032695)4.19360471
13negative regulation of phagocytosis (GO:0050765)4.07817641
14regulation of B cell differentiation (GO:0045577)3.91175013
15antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.90860119
16regulation of gamma-delta T cell differentiation (GO:0045586)3.89357666
17regulation of mast cell degranulation (GO:0043304)3.87716876
18B cell receptor signaling pathway (GO:0050853)3.84854109
19viral transcription (GO:0019083)3.81496065
20response to muramyl dipeptide (GO:0032495)3.80564508
21neutrophil activation (GO:0042119)3.78695116
22telomere maintenance via semi-conservative replication (GO:0032201)3.77394272
23mast cell activation (GO:0045576)3.76266110
24Arp2/3 complex-mediated actin nucleation (GO:0034314)3.75700248
25negative regulation of lymphocyte mediated immunity (GO:0002707)3.74549786
26antigen processing and presentation via MHC class Ib (GO:0002475)3.73533047
27DNA strand elongation involved in DNA replication (GO:0006271)3.71182673
28detection of external biotic stimulus (GO:0098581)3.68940594
29negative regulation of T cell mediated immunity (GO:0002710)3.67729494
30positive regulation of mast cell activation (GO:0033005)3.67207980
31leukocyte aggregation (GO:0070486)3.65064958
32translational termination (GO:0006415)3.63610185
33regulation of mast cell activation involved in immune response (GO:0033006)3.61513965
34regulation of myeloid leukocyte mediated immunity (GO:0002886)3.61158867
35DNA unwinding involved in DNA replication (GO:0006268)3.56651817
36DNA strand elongation (GO:0022616)3.56027050
37regulation of antigen processing and presentation of peptide antigen (GO:0002583)3.55508124
38regulation of gamma-delta T cell activation (GO:0046643)3.55092261
39granulocyte activation (GO:0036230)3.51518546
40negative regulation of leukocyte mediated immunity (GO:0002704)3.46867041
41regulation of leukocyte degranulation (GO:0043300)3.45950325
42regulation of mast cell activation (GO:0033003)3.44845836
43microglial cell activation (GO:0001774)3.44536442
44positive regulation of mast cell activation involved in immune response (GO:0033008)3.44072523
45positive regulation of mast cell degranulation (GO:0043306)3.44072523
46regulation of T cell tolerance induction (GO:0002664)3.43402603
47regulation of tolerance induction (GO:0002643)3.42548815
48DNA deamination (GO:0045006)3.42136239
49T cell selection (GO:0045058)3.38990648
50positive T cell selection (GO:0043368)3.38217746
51interferon-gamma-mediated signaling pathway (GO:0060333)3.35724766
52response to immune response of other organism involved in symbiotic interaction (GO:0052564)3.33953789
53response to host immune response (GO:0052572)3.33953789
54positive regulation of interleukin-2 biosynthetic process (GO:0045086)3.32173999
55detection of biotic stimulus (GO:0009595)3.29494545
56telomere maintenance via recombination (GO:0000722)3.28022170
57mast cell degranulation (GO:0043303)3.27274376
58mast cell activation involved in immune response (GO:0002279)3.27274376
59translational elongation (GO:0006414)3.25428764
60regulation of antigen processing and presentation (GO:0002577)3.25182609
61regulation of dendritic cell antigen processing and presentation (GO:0002604)3.23906421
62thymic T cell selection (GO:0045061)3.22166743
63detection of molecule of bacterial origin (GO:0032490)3.20335041
64positive regulation of antigen processing and presentation (GO:0002579)3.19600826
65SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.19181794
66immunoglobulin mediated immune response (GO:0016064)3.18273559
67T cell homeostasis (GO:0043029)3.17577896
68cellular response to zinc ion (GO:0071294)3.16719916
69macrophage activation (GO:0042116)3.15073876
70type I interferon signaling pathway (GO:0060337)3.14274952
71cellular response to type I interferon (GO:0071357)3.14274952
72response to type I interferon (GO:0034340)3.12936687
73negative regulation of cell killing (GO:0031342)3.11113326
74negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.11113326
75germinal center formation (GO:0002467)3.10358822
76cotranslational protein targeting to membrane (GO:0006613)3.10294239
77negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)3.10229497
78protein targeting to ER (GO:0045047)3.09371654
79cellular response to interleukin-15 (GO:0071350)3.07269297
80response to host (GO:0075136)3.06389596
81response to host defenses (GO:0052200)3.06389596
82response to defenses of other organism involved in symbiotic interaction (GO:0052173)3.06389596
83positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)3.06338361
84regulation of alpha-beta T cell proliferation (GO:0046640)3.05706996
85activated T cell proliferation (GO:0050798)3.01676017
86mitotic recombination (GO:0006312)3.01507324
87regulation of antigen receptor-mediated signaling pathway (GO:0050854)2.99517384
88positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)2.99278339
89negative T cell selection (GO:0043383)2.96035778
90ribosomal small subunit biogenesis (GO:0042274)2.96026398
91nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.95514234
92establishment of protein localization to endoplasmic reticulum (GO:0072599)2.94185490
93respiratory burst (GO:0045730)2.93942464
94positive regulation of myeloid leukocyte mediated immunity (GO:0002888)2.93699612
95negative regulation of innate immune response (GO:0045824)2.92115850
96negative thymic T cell selection (GO:0045060)2.91678543
97protein localization to endoplasmic reticulum (GO:0070972)2.91224716
98regulation of tumor necrosis factor biosynthetic process (GO:0042534)2.91187309
99response to protozoan (GO:0001562)2.90021456
100production of molecular mediator involved in inflammatory response (GO:0002532)2.88967350
101regulation of regulated secretory pathway (GO:1903305)2.88462579
102defense response to protozoan (GO:0042832)2.88361509
103megakaryocyte development (GO:0035855)2.88164663
104DNA replication initiation (GO:0006270)2.86530072
105negative regulation of interleukin-6 production (GO:0032715)2.86158623
106viral life cycle (GO:0019058)2.84185232
107negative regulation of cytokine production involved in immune response (GO:0002719)2.83153654
108response to interleukin-15 (GO:0070672)2.82006806
109lymphocyte homeostasis (GO:0002260)2.79755335
110positive thymic T cell selection (GO:0045059)2.77912899
111B cell mediated immunity (GO:0019724)2.77487770
112actin nucleation (GO:0045010)2.76867411
113definitive hemopoiesis (GO:0060216)2.76577326
114cellular protein complex disassembly (GO:0043624)2.75943955
115nucleotide-excision repair, DNA gap filling (GO:0006297)2.75614832
116myeloid dendritic cell activation (GO:0001773)2.75238854
117T cell migration (GO:0072678)2.74345824
118translational initiation (GO:0006413)2.73233697
119interferon-gamma production (GO:0032609)2.71815038
120telomere maintenance via telomere lengthening (GO:0010833)2.69735073
121antigen receptor-mediated signaling pathway (GO:0050851)2.69389480
122tolerance induction (GO:0002507)2.68787880
123regulation of T cell receptor signaling pathway (GO:0050856)2.67402870
124positive regulation of granulocyte differentiation (GO:0030854)2.66156112
1253-UTR-mediated mRNA stabilization (GO:0070935)2.64554874
126cellular response to interferon-beta (GO:0035458)2.64325503
127maturation of SSU-rRNA (GO:0030490)2.62929560
128regulation of interferon-beta biosynthetic process (GO:0045357)2.62678841
129leukocyte homeostasis (GO:0001776)2.60738286
130cellular extravasation (GO:0045123)2.59499662
131positive regulation of lamellipodium assembly (GO:0010592)2.59203710
132regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.57894089
133protein localization to kinetochore (GO:0034501)2.56806893
134response to interferon-beta (GO:0035456)2.56749369
135protein complex disassembly (GO:0043241)2.54762195
136response to fungus (GO:0009620)2.53987358
137neutrophil activation involved in immune response (GO:0002283)2.53447953
138negative regulation of RNA splicing (GO:0033119)2.53285535
139leukocyte degranulation (GO:0043299)2.52203605
140response to peptidoglycan (GO:0032494)2.51849247
141negative regulation of erythrocyte differentiation (GO:0045647)2.51572686
142positive regulation by symbiont of host defense response (GO:0052509)2.51407686
143modulation by symbiont of host defense response (GO:0052031)2.51407686
144modulation by organism of immune response of other organism involved in symbiotic interaction (GO:002.51407686
145modulation by organism of defense response of other organism involved in symbiotic interaction (GO:02.51407686
146positive regulation by organism of defense response of other organism involved in symbiotic interact2.51407686
147modulation by symbiont of host immune response (GO:0052553)2.51407686
148myeloid cell activation involved in immune response (GO:0002275)2.51301847
149pinocytosis (GO:0006907)2.50299529
150neutrophil mediated immunity (GO:0002446)2.49491181
151regulation of interleukin-12 biosynthetic process (GO:0045075)2.48625115
152pentose-phosphate shunt (GO:0006098)2.46265088
153lymphoid progenitor cell differentiation (GO:0002320)2.45531331
154B cell homeostasis (GO:0001782)2.45421426
155regulation of erythrocyte differentiation (GO:0045646)2.45218537

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.16154684
2IRF8_22096565_ChIP-ChIP_GC-B_Human3.31867696
3MECOM_23826213_ChIP-Seq_KASUMI_Mouse3.07995551
4MYC_22102868_ChIP-Seq_BL_Human3.06063611
5EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.98062754
6EGR1_19374776_ChIP-ChIP_THP-1_Human2.89832939
7VDR_21846776_ChIP-Seq_THP-1_Human2.88332087
8IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.83819290
9STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.82326200
10SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.72217301
11SCL_19346495_ChIP-Seq_HPC-7_Human2.71461304
12SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.71253037
13IRF8_21731497_ChIP-ChIP_J774_Mouse2.71006831
14FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.65892264
15FOXM1_23109430_ChIP-Seq_U2OS_Human2.58566128
16MYB_21317192_ChIP-Seq_ERMYB_Mouse2.52849832
17RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.43466505
18BP1_19119308_ChIP-ChIP_Hs578T_Human2.43231473
19E2F4_17652178_ChIP-ChIP_JURKAT_Human2.41470226
20VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human2.40389371
21MYC_18555785_ChIP-Seq_MESCs_Mouse2.23266103
22* SPI1_23547873_ChIP-Seq_NB4_Human2.22341983
23TAL1_20887958_ChIP-Seq_HPC-7_Mouse2.19059940
24ELF1_17652178_ChIP-ChIP_JURKAT_Human2.16415534
25* MYB_26560356_Chip-Seq_TH2_Human2.13311644
26* FLI1_20887958_ChIP-Seq_HPC-7_Mouse2.12197141
27ASXL1_24218140_ChIP-Seq_BMDM_Mouse2.04551900
28STAT4_19710469_ChIP-ChIP_TH1__Mouse2.04405243
29VDR_24763502_ChIP-Seq_THP-1_Human2.03480046
30MAF_26560356_Chip-Seq_TH1_Human2.01299518
31MYB_26560356_Chip-Seq_TH1_Human1.90583035
32* SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.89951229
33RUNX1_22412390_ChIP-Seq_EML_Mouse1.89778056
34* NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.89050668
35UTX_26944678_Chip-Seq_JUKART_Human1.88976791
36IRF8_27001747_Chip-Seq_BMDM_Mouse1.88911449
37* KDM2B_26808549_Chip-Seq_SUP-B15_Human1.87595483
38SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.86606695
39FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.86314057
40SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.84806038
41NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.81960986
42* BRD4_27068464_Chip-Seq_AML-cells_Mouse1.81523251
43IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.79271485
44VDR_24787735_ChIP-Seq_THP-1_Human1.77656497
45FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.71790226
46STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.70017747
47* CIITA_25753668_ChIP-Seq_RAJI_Human1.67903476
48HOXB4_20404135_ChIP-ChIP_EML_Mouse1.66169139
49RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.65661550
50ERG_20887958_ChIP-Seq_HPC-7_Mouse1.64770542
51VDR_23849224_ChIP-Seq_CD4+_Human1.63132427
52* TCF7_22412390_ChIP-Seq_EML_Mouse1.61252216
53Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.60435069
54MYC_18358816_ChIP-ChIP_MESCs_Mouse1.60033057
55NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.57435536
56* MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.55516079
57RUNX_20019798_ChIP-Seq_JUKART_Human1.55499561
58EST1_17652178_ChIP-ChIP_JURKAT_Human1.54543887
59FOXP3_21729870_ChIP-Seq_TREG_Human1.53864062
60NOTCH1_21737748_ChIP-Seq_TLL_Human1.50568039
61GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.49389494
62MYC_19079543_ChIP-ChIP_MESCs_Mouse1.48997920
63E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.48847751
64* GATA1_19941827_ChIP-Seq_MEL_Mouse1.48179803
65MYC_19030024_ChIP-ChIP_MESCs_Mouse1.43730214
66GATA1_22383799_ChIP-Seq_G1ME_Mouse1.42321758
67GABP_17652178_ChIP-ChIP_JURKAT_Human1.41837322
68E2F1_21310950_ChIP-Seq_MCF-7_Human1.40890282
69XRN2_22483619_ChIP-Seq_HELA_Human1.40529187
70LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.39181584
71GATA2_22383799_ChIP-Seq_G1ME_Mouse1.38019123
72GATA3_26560356_Chip-Seq_TH2_Human1.37515895
73HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.37145554
74SPI1_23127762_ChIP-Seq_K562_Human1.36342929
75MAF_26560356_Chip-Seq_TH2_Human1.35733877
76ETS1_20019798_ChIP-Seq_JURKAT_Human1.33817035
77LXR_22292898_ChIP-Seq_THP-1_Human1.31856259
78PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.31712522
79NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.29991843
80JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.28227241
81LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.26757589
82GATA1_22025678_ChIP-Seq_K562_Human1.26228669
83GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.20592724
84PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.20507171
85FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.20081037
86THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.18745119
87BCL6_27268052_Chip-Seq_Bcells_Human1.18291337
88KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.18163559
89* CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse1.17009936
90GATA3_27048872_Chip-Seq_THYMUS_Human1.16618209
91IKZF1_21737484_ChIP-ChIP_HCT116_Human1.15474942
92KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.15255368
93GATA1_19941826_ChIP-Seq_K562_Human1.15171450
94TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.15145119
95* CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse1.14687482
96SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.14468449
97TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.13591482
98VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.12948384
99* KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.11925246
100KDM2B_26808549_Chip-Seq_JURKAT_Human1.10938723
101GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.10753805
102SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.09634203
103BCOR_27268052_Chip-Seq_Bcells_Human1.09420692
104PU_27001747_Chip-Seq_BMDM_Mouse1.09251580
105NELFA_20434984_ChIP-Seq_ESCs_Mouse1.07929243
106GABP_19822575_ChIP-Seq_HepG2_Human1.06725952
107CREB1_15753290_ChIP-ChIP_HEK293T_Human1.06089516
108* PU.1_20513432_ChIP-Seq_Bcells_Mouse1.05236595
109DCP1A_22483619_ChIP-Seq_HELA_Human1.04205101
110GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.03841050
111PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.02117387
112CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.01269863
113ELF1_20517297_ChIP-Seq_JURKAT_Human1.00778249
114RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.99603350
115MYCN_21190229_ChIP-Seq_SHEP-21N_Human0.99558122
116ELK1_19687146_ChIP-ChIP_HELA_Human0.98970267
117TTF2_22483619_ChIP-Seq_HELA_Human0.98752693
118NCOR1_26117541_ChIP-Seq_K562_Human0.98559695
119KDM5A_27292631_Chip-Seq_BREAST_Human0.98094629
120NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.96715868
121TFEB_21752829_ChIP-Seq_HELA_Human0.96206173
122PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.95141196
123ELK3_25401928_ChIP-Seq_HUVEC_Human0.93497049
124* KDM2B_26808549_Chip-Seq_DND41_Human0.92102903
125CTCF_27219007_Chip-Seq_ERYTHROID_Human0.90763395
126FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.90298133
127STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.89774763
128* CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.89405007
129PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse0.89243384
130SPI1_20517297_ChIP-Seq_HL60_Human0.86130841
131GATA2_19941826_ChIP-Seq_K562_Human0.85510104
132RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.85149295
133* CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.83995920
134STAT6_21828071_ChIP-Seq_BEAS2B_Human0.83811752
135SMAD_19615063_ChIP-ChIP_OVARY_Human0.82703283

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001835_abnormal_antigen_presentation4.03437032
2MP0002396_abnormal_hematopoietic_system3.74990928
3MP0005671_abnormal_response_to3.04133242
4MP0003763_abnormal_thymus_physiology3.00221271
5MP0000685_abnormal_immune_system2.98968892
6MP0001800_abnormal_humoral_immune2.83042897
7MP0009785_altered_susceptibility_to2.65488500
8MP0002398_abnormal_bone_marrow2.62628519
9MP0003436_decreased_susceptibility_to2.60854279
10MP0003303_peritoneal_inflammation2.57982782
11MP0002452_abnormal_antigen_presenting2.56167263
12MP0002420_abnormal_adaptive_immunity2.54839881
13MP0005000_abnormal_immune_tolerance2.52240956
14MP0001819_abnormal_immune_cell2.51221918
15MP0005025_abnormal_response_to2.47158934
16MP0002723_abnormal_immune_serum2.46709634
17MP0005464_abnormal_platelet_physiology2.45488955
18MP0001790_abnormal_immune_system2.44419414
19MP0005387_immune_system_phenotype2.44419414
20MP0004808_abnormal_hematopoietic_stem2.38504951
21MP0002419_abnormal_innate_immunity2.37548593
22MP0003693_abnormal_embryo_hatching2.35974843
23MP0002166_altered_tumor_susceptibility2.26827983
24MP0000716_abnormal_immune_system2.25845232
25MP0000689_abnormal_spleen_morphology2.22768770
26MP0005397_hematopoietic_system_phenotyp2.20861190
27MP0001545_abnormal_hematopoietic_system2.20861190
28MP0008057_abnormal_DNA_replication2.20029123
29MP0010094_abnormal_chromosome_stability2.19657244
30MP0005174_abnormal_tail_pigmentation2.15856871
31MP0002722_abnormal_immune_system2.15516485
32MP0002148_abnormal_hypersensitivity_rea2.14112609
33MP0009333_abnormal_splenocyte_physiolog2.11624342
34MP0002405_respiratory_system_inflammati2.09216458
35MP0000465_gastrointestinal_hemorrhage2.01276080
36MP0002429_abnormal_blood_cell2.00014542
37MP0000703_abnormal_thymus_morphology1.93731113
38MP0001853_heart_inflammation1.89969408
39MP0009278_abnormal_bone_marrow1.89417614
40MP0000490_abnormal_crypts_of1.86722668
41MP0001873_stomach_inflammation1.83541769
42MP0002006_tumorigenesis1.82339075
43MP0010155_abnormal_intestine_physiology1.81224996
44MP0003300_gastrointestinal_ulcer1.78262696
45MP0005075_abnormal_melanosome_morpholog1.71636043
46MP0003172_abnormal_lysosome_physiology1.67302874
47MP0003077_abnormal_cell_cycle1.64391692
48MP0001845_abnormal_inflammatory_respons1.62211609
49MP0006082_CNS_inflammation1.57212627
50MP0003866_abnormal_defecation1.57058854
51MP0003111_abnormal_nucleus_morphology1.56170819
52MP0003724_increased_susceptibility_to1.54618661
53MP0008260_abnormal_autophagy1.53691833
54MP0002019_abnormal_tumor_incidence1.38097747
55MP0004957_abnormal_blastocyst_morpholog1.35751606
56MP0000015_abnormal_ear_pigmentation1.32440891
57MP0008058_abnormal_DNA_repair1.32059487
58MP0002095_abnormal_skin_pigmentation1.31676551
59MP0002998_abnormal_bone_remodeling1.31580695
60MP0003183_abnormal_peptide_metabolism1.31301908
61MP0010307_abnormal_tumor_latency1.31055622
62MP0008007_abnormal_cellular_replicative1.29377687
63MP0004947_skin_inflammation1.28948471
64MP0000858_altered_metastatic_potential1.28165581
65MP0005451_abnormal_body_composition1.22350439
66MP0005058_abnormal_lysosome_morphology1.20041185
67MP0008469_abnormal_protein_level1.18546350
68MP0010352_gastrointestinal_tract_polyps1.09686423
69MP0001533_abnormal_skeleton_physiology1.09654749
70MP0002933_joint_inflammation1.08184240
71MP0003191_abnormal_cellular_cholesterol1.05140435
72MP0004883_abnormal_blood_vessel1.04952279
73MP0004381_abnormal_hair_follicle1.04532583
74MP0005310_abnormal_salivary_gland1.02919861
75MP0005166_decreased_susceptibility_to1.00419484
76MP0002138_abnormal_hepatobiliary_system0.98003289
77MP0003690_abnormal_glial_cell0.95310190
78MP0000313_abnormal_cell_death0.95084117
79MP0000343_altered_response_to0.94379873
80MP0000604_amyloidosis0.92995139
81MP0002009_preneoplasia0.90308498
82MP0003448_altered_tumor_morphology0.87824873
83MP0006054_spinal_hemorrhage0.86754349
84MP0003656_abnormal_erythrocyte_physiolo0.84194778
85MP0000350_abnormal_cell_proliferation0.81408299
86MP0005390_skeleton_phenotype0.81353662
87MP0008004_abnormal_stomach_pH0.80156310
88MP0005164_abnormal_response_to0.78896878
89MP0004510_myositis0.78856180
90MP0003806_abnormal_nucleotide_metabolis0.78320269
91MP0002277_abnormal_respiratory_mucosa0.77979595
92MP0000371_diluted_coat_color0.75472408
93MP0001851_eye_inflammation0.75030479
94MP0001986_abnormal_taste_sensitivity0.74917876
95MP0001663_abnormal_digestive_system0.74554201
96MP0008873_increased_physiological_sensi0.67271786
97MP0003795_abnormal_bone_structure0.65448096
98MP0009763_increased_sensitivity_to0.64839239
99MP0003828_pulmonary_edema0.61974355
100MP0003786_premature_aging0.61568690
101MP0002132_abnormal_respiratory_system0.60686876
102MP0002075_abnormal_coat/hair_pigmentati0.58309815
103MP0001730_embryonic_growth_arrest0.58136926
104MP0000477_abnormal_intestine_morphology0.57664103
105MP0003075_altered_response_to0.56152814
106MP0003943_abnormal_hepatobiliary_system0.55913351
107MP0009764_decreased_sensitivity_to0.54142431
108MP0008874_decreased_physiological_sensi0.52917374
109MP0009115_abnormal_fat_cell0.52536044
110MP0000249_abnormal_blood_vessel0.51123824
111MP0003045_fibrosis0.51050767
112MP0009840_abnormal_foam_cell0.50522110
113MP0005076_abnormal_cell_differentiation0.50427780
114MP0000598_abnormal_liver_morphology0.50257155
115MP0004130_abnormal_muscle_cell0.49977445
116MP0005023_abnormal_wound_healing0.49845517
117MP0005319_abnormal_enzyme/_coenzyme0.49326689
118MP0008877_abnormal_DNA_methylation0.46769223
119MP0002877_abnormal_melanocyte_morpholog0.46604095
120MP0002080_prenatal_lethality0.46429786
121MP0005535_abnormal_body_temperature0.46070213
122MP0009765_abnormal_xenobiotic_induced0.45381441
123MP0000609_abnormal_liver_physiology0.45021247
124MP0002693_abnormal_pancreas_physiology0.44804265
125MP0003091_abnormal_cell_migration0.44085320
126MP0005381_digestive/alimentary_phenotyp0.43987410
127MP0005334_abnormal_fat_pad0.41559579

Predicted human phenotypes

RankGene SetZ-score
1IgM deficiency (HP:0002850)4.98247493
2Recurrent abscess formation (HP:0002722)4.73518792
3Chronic otitis media (HP:0000389)4.64421051
4Thrombocytosis (HP:0001894)4.47437002
5Elevated erythrocyte sedimentation rate (HP:0003565)4.37426716
6Recurrent viral infections (HP:0004429)4.25512640
7Recurrent bacterial skin infections (HP:0005406)4.21362450
8Eczematoid dermatitis (HP:0000976)4.20759982
9Myositis (HP:0100614)4.00895830
10Recurrent fungal infections (HP:0002841)4.00846574
11Recurrent bronchitis (HP:0002837)3.89737415
12Panhypogammaglobulinemia (HP:0003139)3.85073196
13Meningitis (HP:0001287)3.69781583
14Cellulitis (HP:0100658)3.64508782
15Abnormal delayed hypersensitivity skin test (HP:0002963)3.62971553
16Gastrointestinal infarctions (HP:0005244)3.53558455
17Abnormality of T cells (HP:0002843)3.52027934
18Abnormality of T cell physiology (HP:0011840)3.49567354
19Abnormality of B cell number (HP:0010975)3.45003797
20B lymphocytopenia (HP:0010976)3.45003797
21Petechiae (HP:0000967)3.39926627
22Obstructive lung disease (HP:0006536)3.31603100
23Chronic obstructive pulmonary disease (HP:0006510)3.31603100
24T lymphocytopenia (HP:0005403)3.26405559
25Agammaglobulinemia (HP:0004432)3.22334748
26Gastrointestinal inflammation (HP:0004386)3.18744573
27Recurrent skin infections (HP:0001581)3.14167731
28Mediastinal lymphadenopathy (HP:0100721)3.13921446
29Inflammation of the large intestine (HP:0002037)3.12670140
30Pulmonary infiltrates (HP:0002113)3.10735517
31Abnormality of cells of the erythroid lineage (HP:0012130)3.10150756
32Abnormality of T cell number (HP:0011839)3.07423362
33Urticaria (HP:0001025)3.06197213
34Nasal polyposis (HP:0100582)3.05969335
35Abnormal number of erythroid precursors (HP:0012131)3.05171455
36Reticulocytopenia (HP:0001896)3.04906783
37Prolonged bleeding time (HP:0003010)3.01881692
38Gingivitis (HP:0000230)3.01733059
39Thyroiditis (HP:0100646)3.00703673
40Keratoconjunctivitis sicca (HP:0001097)2.94825787
41Recurrent cutaneous fungal infections (HP:0011370)2.92860684
42Chronic mucocutaneous candidiasis (HP:0002728)2.92860684
43IgG deficiency (HP:0004315)2.92643808
44Increased cerebral lipofuscin (HP:0011813)2.91330719
45Lymphopenia (HP:0001888)2.83849617
46Abnormality of glycolipid metabolism (HP:0010969)2.82314400
47Abnormality of liposaccharide metabolism (HP:0010968)2.82314400
48Abnormality of glycosphingolipid metabolism (HP:0004343)2.82314400
49Abnormality of cells of the lymphoid lineage (HP:0012140)2.79933254
50Abnormality of the nasal mucosa (HP:0000433)2.74092436
51Keratoconjunctivitis (HP:0001096)2.73649599
52Colitis (HP:0002583)2.71830571
53Spontaneous hematomas (HP:0007420)2.71016868
54Lymphoma (HP:0002665)2.67619521
55Granulocytopenia (HP:0001913)2.66419938
56Recurrent gram-negative bacterial infections (HP:0005420)2.66108533
57Eosinophilia (HP:0001880)2.65947368
58Vasculitis (HP:0002633)2.63877681
59Poikiloderma (HP:0001029)2.63855885
60Epistaxis (HP:0000421)2.62460222
61Severe combined immunodeficiency (HP:0004430)2.58818448
62Pustule (HP:0200039)2.58030138
63Aplastic anemia (HP:0001915)2.57633553
64Abnormality of macrophages (HP:0004311)2.57020012
65Increased neuronal autofluorescent lipopigment (HP:0002074)2.56369807
66Abnormal platelet function (HP:0011869)2.52619054
67Impaired platelet aggregation (HP:0003540)2.52619054
68Abnormality of the prostate (HP:0008775)2.51682799
69Pulmonary embolism (HP:0002204)2.48650278
70Amyloidosis (HP:0011034)2.48477204
71Combined immunodeficiency (HP:0005387)2.47039614
72Interstitial pulmonary disease (HP:0006530)2.45297474
73Dysostosis multiplex (HP:0000943)2.44104854
74Increased IgM level (HP:0003496)2.43930214
75Abnormality of eosinophils (HP:0001879)2.43435062
76Abnormality of the fingertips (HP:0001211)2.43393258
77Osteomyelitis (HP:0002754)2.42683803
78Encephalitis (HP:0002383)2.42392983
79IgA deficiency (HP:0002720)2.42055491
80Hypochromic anemia (HP:0001931)2.40149858
81Episodic fever (HP:0001954)2.40058500
82Leukocytosis (HP:0001974)2.37665698
83Stomatitis (HP:0010280)2.35107980
84Recurrent sinusitis (HP:0011108)2.34505608
85Autoimmune hemolytic anemia (HP:0001890)2.33538858
86Verrucae (HP:0200043)2.33516821
87Papilloma (HP:0012740)2.33516821
88Acute myeloid leukemia (HP:0004808)2.32565210
89Chronic sinusitis (HP:0011109)2.28998713
90Loss of speech (HP:0002371)2.28692304
91Gastrointestinal stroma tumor (HP:0100723)2.28304122
92Chest pain (HP:0100749)2.26927331
93Abnormality of the pleura (HP:0002103)2.26045109
94Purpura (HP:0000979)2.25887072
95Hepatosplenomegaly (HP:0001433)2.25642041
96Systemic lupus erythematosus (HP:0002725)2.25342736
97Increased IgE level (HP:0003212)2.25336193
98Hypochromic microcytic anemia (HP:0004840)2.25199052
99Periodontitis (HP:0000704)2.24783508
100Papilledema (HP:0001085)2.24416911
101Orchitis (HP:0100796)2.22088176
102Agnosia (HP:0010524)2.21055648
103Vacuolated lymphocytes (HP:0001922)2.20777995
104Acute lymphatic leukemia (HP:0006721)2.20379744
105Increased serum ferritin (HP:0003281)2.20220212
106Viral hepatitis (HP:0006562)2.20138511
107Abnormal platelet volume (HP:0011876)2.17768677
108Hypergammaglobulinemia (HP:0010702)2.16824132
109Anorexia (HP:0002039)2.16612101
110Myelodysplasia (HP:0002863)2.15036185
111Albinism (HP:0001022)2.14908564
112Hypoplasia of the thymus (HP:0000778)2.13384923
113Gangrene (HP:0100758)2.12576818
114Retrobulbar optic neuritis (HP:0100654)2.12200501
115Optic neuritis (HP:0100653)2.12200501
116Bronchitis (HP:0012387)2.11886832
117Pallor (HP:0000980)2.10853598
118Autoimmune thrombocytopenia (HP:0001973)2.10794144
119Amaurosis fugax (HP:0100576)2.09522749
120Restrictive lung disease (HP:0002091)2.09379599
121Skin ulcer (HP:0200042)2.09330067
122Gingival bleeding (HP:0000225)2.08678458
123Recurrent lower respiratory tract infections (HP:0002783)2.07733695
124Basal cell carcinoma (HP:0002671)2.07151203
125Sepsis (HP:0100806)2.06063824
126Skin rash (HP:0000988)2.04867633
127Hemoptysis (HP:0002105)2.04087624
128Abnormality of iron homeostasis (HP:0011031)2.03349245
129Glomerulopathy (HP:0100820)2.02863377
130Recurrent pneumonia (HP:0006532)2.02777618
131Chronic diarrhea (HP:0002028)2.01155627
132Pulmonary fibrosis (HP:0002206)1.99238500
133Arterial thrombosis (HP:0004420)1.98418532

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP4K14.70506861
2EEF2K3.42839353
3KIT2.84723359
4PRPF4B2.76505331
5BTK2.51719836
6BLK2.49821280
7TXK2.34035216
8ZAP702.26565665
9IRAK42.20428758
10CSF1R2.17478204
11TEC2.15822888
12FLT32.06283650
13SYK1.96238675
14GRK61.85604223
15STK101.80424598
16TYK21.77639178
17JAK31.77186598
18FES1.72758611
19CDC71.71302300
20ITK1.65551125
21CLK11.59822206
22PKN21.58594226
23BMPR21.49051102
24STK161.47598929
25TBK11.46704266
26PIM21.45690407
27MAP2K31.44797435
28LRRK21.44114010
29NME21.42890043
30MAP3K101.41210940
31RPS6KB21.37270242
32TESK21.35575529
33FGR1.34766084
34LCK1.33602048
35WEE11.29232161
36MATK1.27851078
37SCYL21.26545907
38NEK21.25816640
39LYN1.25540550
40PIM11.22460238
41HCK1.21876145
42TAOK11.20850784
43IKBKE1.20641147
44CSK1.19249417
45MAP3K31.19242163
46ERN11.12635799
47MARK31.12318627
48TAOK31.10293768
49TGFBR21.09729030
50RIPK41.04788133
51VRK10.99744156
52TGFBR10.96519985
53RPS6KA40.96287246
54IKBKB0.95151405
55MAP3K10.94295927
56MAPKAPK30.89837701
57ATR0.89111762
58STK40.88757587
59PDK10.87957529
60MAP3K140.87201474
61TNK20.84821242
62CDK40.84805151
63MARK20.83783509
64EIF2AK30.80739863
65PASK0.79584645
66CDC42BPA0.79509196
67JAK10.79160094
68MAPK120.77703646
69TRPM70.77091305
70EIF2AK10.77040860
71TAOK20.76641445
72SIK20.76312686
73BUB10.75843798
74TRIB30.75697106
75PDPK10.75396671
76PRKCQ0.74865652
77MAP3K110.74337147
78GRK70.73737030
79KDR0.72802284
80MAPK70.72165525
81YES10.71493046
82TSSK60.70548494
83ACVR1B0.70077167
84CDK190.69967902
85SMG10.69938327
86MAP3K60.69155822
87EPHB10.68291547
88MAPK110.68219700
89CDK70.68031767
90MAPK40.67570942
91PAK40.66336010
92IRAK10.66313473
93MAP3K120.62748747
94MAP3K80.61733329
95IRAK30.61408905
96PRKD20.60820980
97PIK3CG0.59348656
98DAPK10.58186697
99BRSK20.57572024
100RPS6KA60.57142114
101MAP3K70.56223873
102FYN0.56039863
103NLK0.55374156
104CAMKK10.55195008
105IRAK20.54902847
106JAK20.53708853
107SRPK10.52712291
108MAP3K130.52248811
109CDK60.52017650
110HIPK20.51545717
111RPS6KC10.50286227
112RPS6KL10.50286227
113SIK30.50222870
114CAMKK20.48546177
115RIPK10.47992192
116MST40.47665568
117KSR20.47497503
118PTK60.46510844
119DYRK30.46260104
120RAF10.46164591
121ALK0.45728411
122CCNB10.45188677
123FGFR30.43919228
124MAP2K20.43398888
125TLK10.43173404
126AURKB0.42687989
127MKNK10.41513416
128NEK90.41193887
129FGFR40.41114982
130MAPKAPK20.40504290
131CDK120.40416639
132MAP3K50.36974776
133MAP2K60.35762255
134ABL10.33211205
135STK110.33081154
136DYRK1B0.32116960
137SIK10.30421325
138CHUK0.30135388
139RET0.28588280
140MOS0.26779606
141PRKCD0.26706928

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.19652925
2Primary immunodeficiency_Homo sapiens_hsa053403.64505798
3Mismatch repair_Homo sapiens_hsa034303.09290666
4Ribosome_Homo sapiens_hsa030102.79595607
5Base excision repair_Homo sapiens_hsa034102.65598474
6B cell receptor signaling pathway_Homo sapiens_hsa046622.35644638
7Leishmaniasis_Homo sapiens_hsa051402.25178737
8Antigen processing and presentation_Homo sapiens_hsa046122.23360799
9Homologous recombination_Homo sapiens_hsa034402.05357140
10Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.95677716
11Hematopoietic cell lineage_Homo sapiens_hsa046401.89103911
12Non-homologous end-joining_Homo sapiens_hsa034501.88388501
13Measles_Homo sapiens_hsa051621.87046318
14NF-kappa B signaling pathway_Homo sapiens_hsa040641.83080891
15Spliceosome_Homo sapiens_hsa030401.82638178
16Intestinal immune network for IgA production_Homo sapiens_hsa046721.81577819
17Osteoclast differentiation_Homo sapiens_hsa043801.72266270
18Nucleotide excision repair_Homo sapiens_hsa034201.66530009
19Herpes simplex infection_Homo sapiens_hsa051681.63573077
20Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.59906349
21Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.59651098
22Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.56046404
23T cell receptor signaling pathway_Homo sapiens_hsa046601.51560261
24Rheumatoid arthritis_Homo sapiens_hsa053231.50518271
25Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.49772099
26RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.40910042
27Other glycan degradation_Homo sapiens_hsa005111.36186338
28Cell cycle_Homo sapiens_hsa041101.35363647
29Legionellosis_Homo sapiens_hsa051341.33301516
30Acute myeloid leukemia_Homo sapiens_hsa052211.32827861
31Shigellosis_Homo sapiens_hsa051311.31463744
32Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.24669125
33Toll-like receptor signaling pathway_Homo sapiens_hsa046201.24395762
34Phagosome_Homo sapiens_hsa041451.22139387
35Pyrimidine metabolism_Homo sapiens_hsa002401.21925668
36Jak-STAT signaling pathway_Homo sapiens_hsa046301.21298647
37Fanconi anemia pathway_Homo sapiens_hsa034601.19524586
38Hepatitis B_Homo sapiens_hsa051611.16651619
39One carbon pool by folate_Homo sapiens_hsa006701.12326345
40NOD-like receptor signaling pathway_Homo sapiens_hsa046211.11611444
41Allograft rejection_Homo sapiens_hsa053301.11458714
42Transcriptional misregulation in cancer_Homo sapiens_hsa052021.11123608
43Glycosaminoglycan degradation_Homo sapiens_hsa005311.10507642
44RNA transport_Homo sapiens_hsa030131.09907276
45Pertussis_Homo sapiens_hsa051331.09062160
46Influenza A_Homo sapiens_hsa051641.06331167
47Pentose phosphate pathway_Homo sapiens_hsa000301.04099017
48Apoptosis_Homo sapiens_hsa042101.03640182
49Tuberculosis_Homo sapiens_hsa051521.03323772
50Epstein-Barr virus infection_Homo sapiens_hsa051691.03121645
51African trypanosomiasis_Homo sapiens_hsa051431.02964913
52Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.01401277
53Toxoplasmosis_Homo sapiens_hsa051451.00848501
54Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.98546155
55Proteasome_Homo sapiens_hsa030500.98488684
56Chronic myeloid leukemia_Homo sapiens_hsa052200.98482716
57Leukocyte transendothelial migration_Homo sapiens_hsa046700.98407827
58Asthma_Homo sapiens_hsa053100.97166644
59Platelet activation_Homo sapiens_hsa046110.97102710
60Chemokine signaling pathway_Homo sapiens_hsa040620.92311349
61Viral carcinogenesis_Homo sapiens_hsa052030.91307888
62Viral myocarditis_Homo sapiens_hsa054160.90402600
63RNA degradation_Homo sapiens_hsa030180.89596220
64p53 signaling pathway_Homo sapiens_hsa041150.89207685
65N-Glycan biosynthesis_Homo sapiens_hsa005100.87386187
66Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.87170559
67Graft-versus-host disease_Homo sapiens_hsa053320.86077351
68Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.81593798
69HTLV-I infection_Homo sapiens_hsa051660.77005524
70Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.76921801
71Pancreatic cancer_Homo sapiens_hsa052120.71248024
72Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.70858814
73Staphylococcus aureus infection_Homo sapiens_hsa051500.70540707
74Non-small cell lung cancer_Homo sapiens_hsa052230.70232008
75Malaria_Homo sapiens_hsa051440.69934960
76Salmonella infection_Homo sapiens_hsa051320.69399325
77Systemic lupus erythematosus_Homo sapiens_hsa053220.69257870
78RNA polymerase_Homo sapiens_hsa030200.66506314
79Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.64320281
80SNARE interactions in vesicular transport_Homo sapiens_hsa041300.64303845
81Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.63919952
82Prolactin signaling pathway_Homo sapiens_hsa049170.62924431
83mRNA surveillance pathway_Homo sapiens_hsa030150.62696941
84Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.62214112
85Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.61414378
86Carbohydrate digestion and absorption_Homo sapiens_hsa049730.60660438
87Neurotrophin signaling pathway_Homo sapiens_hsa047220.59476053
88Sphingolipid signaling pathway_Homo sapiens_hsa040710.58841125
89TNF signaling pathway_Homo sapiens_hsa046680.57570816
90Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.57370145
91Colorectal cancer_Homo sapiens_hsa052100.56947914
92Phospholipase D signaling pathway_Homo sapiens_hsa040720.55416600
93Phosphatidylinositol signaling system_Homo sapiens_hsa040700.53272877
94Lysosome_Homo sapiens_hsa041420.52058828
95Thyroid cancer_Homo sapiens_hsa052160.51867421
96Choline metabolism in cancer_Homo sapiens_hsa052310.50449472
97VEGF signaling pathway_Homo sapiens_hsa043700.49713291
98Sulfur relay system_Homo sapiens_hsa041220.47860048
99Endocytosis_Homo sapiens_hsa041440.47457918
100Small cell lung cancer_Homo sapiens_hsa052220.47429610
101Adipocytokine signaling pathway_Homo sapiens_hsa049200.46726371
102Glycerophospholipid metabolism_Homo sapiens_hsa005640.45693230
103Renal cell carcinoma_Homo sapiens_hsa052110.45652857
104Dorso-ventral axis formation_Homo sapiens_hsa043200.43950331
105GnRH signaling pathway_Homo sapiens_hsa049120.43913378
106Notch signaling pathway_Homo sapiens_hsa043300.43840734
107AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.43628065
108Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.42763141
109mTOR signaling pathway_Homo sapiens_hsa041500.42288579
110Hepatitis C_Homo sapiens_hsa051600.41624746
111Insulin resistance_Homo sapiens_hsa049310.39335156
112Protein export_Homo sapiens_hsa030600.38816605
113Amoebiasis_Homo sapiens_hsa051460.38758521
114Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.38728072
115Purine metabolism_Homo sapiens_hsa002300.38633791
116Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.38312571
117FoxO signaling pathway_Homo sapiens_hsa040680.37559987
118Regulation of autophagy_Homo sapiens_hsa041400.36423636
119Drug metabolism - other enzymes_Homo sapiens_hsa009830.35526425
120HIF-1 signaling pathway_Homo sapiens_hsa040660.35198529
121Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.35017922
122Inositol phosphate metabolism_Homo sapiens_hsa005620.34581578
123Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.33981388
124MAPK signaling pathway_Homo sapiens_hsa040100.33958258
125Autoimmune thyroid disease_Homo sapiens_hsa053200.33083957
126Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.32968132
127Type I diabetes mellitus_Homo sapiens_hsa049400.27829277
128Basal transcription factors_Homo sapiens_hsa030220.27747462
129Type II diabetes mellitus_Homo sapiens_hsa049300.26988190
130Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.26351803
131Endometrial cancer_Homo sapiens_hsa052130.24074517
132ErbB signaling pathway_Homo sapiens_hsa040120.19435712
133Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.15022612
134Estrogen signaling pathway_Homo sapiens_hsa049150.13922883

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