PATL1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1nuclear pore complex assembly (GO:0051292)4.37864066
2response to peptidoglycan (GO:0032494)4.06588685
3nuclear pore organization (GO:0006999)3.95286187
4negative regulation of erythrocyte differentiation (GO:0045647)3.81277971
5heterochromatin organization (GO:0070828)3.68486024
6mitotic sister chromatid cohesion (GO:0007064)3.65446585
7pre-miRNA processing (GO:0031054)3.57386532
8regulation of interleukin-12 biosynthetic process (GO:0045075)3.49227586
9protein localization to endosome (GO:0036010)3.33554071
10pore complex assembly (GO:0046931)3.31627258
11protein localization to kinetochore (GO:0034501)3.30652766
12NLS-bearing protein import into nucleus (GO:0006607)3.23413693
13RNA stabilization (GO:0043489)3.21180338
14mRNA stabilization (GO:0048255)3.21180338
15* cytoplasmic mRNA processing body assembly (GO:0033962)3.20172821
16regulation of nucleobase-containing compound transport (GO:0032239)3.19948783
17regulation of early endosome to late endosome transport (GO:2000641)3.07649080
18histone H4-K12 acetylation (GO:0043983)3.04670421
19macrophage activation involved in immune response (GO:0002281)3.02912678
20positive regulation of protein import into nucleus, translocation (GO:0033160)3.02683479
21lipopolysaccharide-mediated signaling pathway (GO:0031663)3.01340193
22regulation of histone H3-K27 methylation (GO:0061085)2.98561774
23germinal center formation (GO:0002467)2.97961012
24response to laminar fluid shear stress (GO:0034616)2.94661744
25mitotic nuclear envelope disassembly (GO:0007077)2.94620728
26positive regulation of gamma-delta T cell activation (GO:0046645)2.94181809
27hypotonic response (GO:0006971)2.93257272
28response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.91798769
29response to host (GO:0075136)2.91798769
30response to host defenses (GO:0052200)2.91798769
31antigen processing and presentation of endogenous peptide antigen (GO:0002483)2.91784680
32detection of other organism (GO:0098543)2.89732628
33antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)2.89512817
34positive regulation of chemokine biosynthetic process (GO:0045080)2.88827222
35detection of molecule of bacterial origin (GO:0032490)2.88711690
36regulation of stem cell maintenance (GO:2000036)2.88121187
37COPI coating of Golgi vesicle (GO:0048205)2.88017857
38Golgi transport vesicle coating (GO:0048200)2.88017857
39regulation of NFAT protein import into nucleus (GO:0051532)2.87213000
40regulation of type I interferon-mediated signaling pathway (GO:0060338)2.85157429
41regulation of necroptotic process (GO:0060544)2.84812278
42NIK/NF-kappaB signaling (GO:0038061)2.81286470
43DNA duplex unwinding (GO:0032508)2.79613569
44regulation of mRNA stability (GO:0043488)2.77929669
45trophectodermal cell differentiation (GO:0001829)2.76667539
46DNA geometric change (GO:0032392)2.76629526
47negative regulation of interleukin-12 production (GO:0032695)2.76140463
483-UTR-mediated mRNA stabilization (GO:0070935)2.75214073
49positive regulation of mitotic sister chromatid separation (GO:1901970)2.73864876
50positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.73864876
51positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.73864876
52nuclear envelope disassembly (GO:0051081)2.73542164
53membrane disassembly (GO:0030397)2.73542164
54pinocytosis (GO:0006907)2.73432264
55detection of bacterium (GO:0016045)2.72252540
56negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.71508936
57negative regulation of translation, ncRNA-mediated (GO:0040033)2.71508936
58regulation of translation, ncRNA-mediated (GO:0045974)2.71508936
59negative regulation of histone methylation (GO:0031061)2.69782129
60modulation by symbiont of host cellular process (GO:0044068)2.68234852
61DNA replication checkpoint (GO:0000076)2.68027468
62positive regulation by symbiont of host defense response (GO:0052509)2.67650813
63modulation by symbiont of host defense response (GO:0052031)2.67650813
64modulation by organism of immune response of other organism involved in symbiotic interaction (GO:002.67650813
65modulation by organism of defense response of other organism involved in symbiotic interaction (GO:02.67650813
66positive regulation by organism of defense response of other organism involved in symbiotic interact2.67650813
67modulation by symbiont of host immune response (GO:0052553)2.67650813
68regulation of integrin activation (GO:0033623)2.66560822
69regulation of RNA stability (GO:0043487)2.66169051
70response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.65829678
71response to host immune response (GO:0052572)2.65829678
72regulation of RNA export from nucleus (GO:0046831)2.65101103
73stress fiber assembly (GO:0043149)2.63803425
74negative regulation of necroptotic process (GO:0060546)2.63482622
75cellular response to type I interferon (GO:0071357)2.63098981
76type I interferon signaling pathway (GO:0060337)2.63098981
77detection of external biotic stimulus (GO:0098581)2.62534940
78histone H3-K36 demethylation (GO:0070544)2.62272812
79antigen processing and presentation of endogenous antigen (GO:0019883)2.61318981
80response to type I interferon (GO:0034340)2.61281395
81regulation of gamma-delta T cell differentiation (GO:0045586)2.60966202
82protein localization to chromosome, centromeric region (GO:0071459)2.60691418
83positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)2.59588607
84cellular response to virus (GO:0098586)2.59194114
85sister chromatid segregation (GO:0000819)2.57921213
86positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.57513864
87negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.56609965
88embryonic process involved in female pregnancy (GO:0060136)2.54594689
89pattern specification involved in kidney development (GO:0061004)2.52249510
90positive regulation of chromosome segregation (GO:0051984)2.50595161
91positive regulation of membrane protein ectodomain proteolysis (GO:0051044)2.50275773
92megakaryocyte development (GO:0035855)2.49667347
93chromatin assembly (GO:0031497)2.49606322
94mitotic sister chromatid segregation (GO:0000070)2.49546595
95positive regulation of Cdc42 GTPase activity (GO:0043089)2.49266887
96skin morphogenesis (GO:0043589)2.48996331
97alternative mRNA splicing, via spliceosome (GO:0000380)2.48480244
98focal adhesion assembly (GO:0048041)2.46906530
99cell-substrate adherens junction assembly (GO:0007045)2.46906530
100positive regulation of SMAD protein import into nucleus (GO:0060391)2.45386969
101response to UV-C (GO:0010225)2.44938121
102positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.44713521
103DNA unwinding involved in DNA replication (GO:0006268)2.44655249
104positive regulation of interferon-alpha production (GO:0032727)2.43261819
105JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)2.42881164
106meiotic chromosome segregation (GO:0045132)2.42043882
107regulation of gamma-delta T cell activation (GO:0046643)2.41610634
108interferon-gamma production (GO:0032609)2.41588496
109positive regulation of histone deacetylation (GO:0031065)2.40927667
110T cell apoptotic process (GO:0070231)2.39732456
111histone H3-K9 modification (GO:0061647)2.39484624
112negative regulation of cell killing (GO:0031342)2.38266139
113negative regulation of leukocyte mediated cytotoxicity (GO:0001911)2.38266139
114activation of Rac GTPase activity (GO:0032863)2.36952464
115regulation of T-helper 2 cell differentiation (GO:0045628)2.36171356
116regulation of hippo signaling (GO:0035330)2.35579167
117positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:003602.35418119
118histone H3-K4 methylation (GO:0051568)2.35057288
119embryonic placenta development (GO:0001892)2.35053103
120negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)2.34956802
121negative regulation of toll-like receptor signaling pathway (GO:0034122)2.34759319
122histone H3-K9 methylation (GO:0051567)2.34314468
123regulation of interferon-gamma-mediated signaling pathway (GO:0060334)2.33608396
124regulation of interferon-alpha production (GO:0032647)2.33491241
125positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO2.32322430
126regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:1900151)2.32322430
127myeloid dendritic cell differentiation (GO:0043011)2.32235011
128negative regulation of RNA splicing (GO:0033119)2.31553738
129negative regulation of mRNA processing (GO:0050686)2.31307486
130cellular extravasation (GO:0045123)2.30953019
131regulation of sister chromatid cohesion (GO:0007063)2.30398301
132negative regulation of viral release from host cell (GO:1902187)2.30244706
133regulation of vitamin D biosynthetic process (GO:0060556)2.29912178
134positive regulation by host of viral transcription (GO:0043923)2.28898111
135dosage compensation (GO:0007549)2.28872185
136detection of biotic stimulus (GO:0009595)2.28047658
137regulation of B cell receptor signaling pathway (GO:0050855)2.27840323
138regulation of interferon-beta biosynthetic process (GO:0045357)2.26894931
139cortical actin cytoskeleton organization (GO:0030866)2.26827412
140nuclear envelope organization (GO:0006998)2.26434801
141antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.25771615
142histone mRNA catabolic process (GO:0071044)2.25066597
143regulation of response to interferon-gamma (GO:0060330)2.23872959
144mitotic chromosome condensation (GO:0007076)2.23840953
145CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369)2.23745122
146positive regulation of macrophage differentiation (GO:0045651)2.22725048
147positive regulation of cellular amide metabolic process (GO:0034250)2.22520136
148immunoglobulin mediated immune response (GO:0016064)2.22427126
149positive regulation of syncytium formation by plasma membrane fusion (GO:0060143)2.22285063
150neutrophil activation involved in immune response (GO:0002283)2.22202557
151modulation by virus of host process (GO:0019054)2.22190171
152regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.22058781
153adherens junction assembly (GO:0034333)2.22056935
154kinetochore organization (GO:0051383)2.22036933
155regulation of posttranscriptional gene silencing (GO:0060147)2.22032869
156regulation of gene silencing by miRNA (GO:0060964)2.22032869
157regulation of gene silencing by RNA (GO:0060966)2.22032869
158positive regulation of mRNA catabolic process (GO:0061014)2.21371080
159mannose metabolic process (GO:0006013)2.21263142
160mammary gland epithelial cell proliferation (GO:0033598)2.20441413
161regulation of translational fidelity (GO:0006450)2.20426738
162regulation of leukocyte degranulation (GO:0043300)2.20283606
163positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.20078493
164positive thymic T cell selection (GO:0045059)2.19787296
165regulation of spindle organization (GO:0090224)2.19667856
166cell-substrate junction assembly (GO:0007044)2.18868544
167regulation of protein import into nucleus, translocation (GO:0033158)2.18304781
168B cell mediated immunity (GO:0019724)2.17962156
169response to muramyl dipeptide (GO:0032495)2.17297279
170regulation of nuclear cell cycle DNA replication (GO:0033262)2.17100560
171nuclear-transcribed mRNA poly(A) tail shortening (GO:0000289)2.17084809
172histone H2A monoubiquitination (GO:0035518)2.17027913
173histone H3-K4 trimethylation (GO:0080182)2.16916630
174positive regulation of extracellular matrix organization (GO:1903055)2.16282640
175membrane raft organization (GO:0031579)2.15986499
176regulation of SMAD protein import into nucleus (GO:0060390)2.15892191
177protein export from nucleus (GO:0006611)2.13694460
178leukocyte aggregation (GO:0070486)2.13594212

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.12326907
2FOXM1_23109430_ChIP-Seq_U2OS_Human4.29091767
3EGR1_19374776_ChIP-ChIP_THP-1_Human4.14143475
4NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse3.52065651
5BP1_19119308_ChIP-ChIP_Hs578T_Human3.47220156
6FOXP3_17237761_ChIP-ChIP_TREG_Mouse3.26872983
7MYC_22102868_ChIP-Seq_BL_Human3.21614309
8STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.76841345
9E2F4_17652178_ChIP-ChIP_JURKAT_Human2.72034777
10TP63_19390658_ChIP-ChIP_HaCaT_Human2.54382911
11FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.24000664
12VDR_21846776_ChIP-Seq_THP-1_Human2.15645312
13TCF7_22412390_ChIP-Seq_EML_Mouse2.08391945
14STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse2.06532165
15* KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.96511447
16IRF8_22096565_ChIP-ChIP_GC-B_Human1.88886721
17STAT6_21828071_ChIP-Seq_BEAS2B_Human1.87114801
18* MAF_26560356_Chip-Seq_TH1_Human1.86707863
19MYB_21317192_ChIP-Seq_ERMYB_Mouse1.84929294
20KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.83117786
21KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.83117786
22KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.83117786
23MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.82699725
24SCL_19346495_ChIP-Seq_HPC-7_Human1.80937354
25MYC_18555785_ChIP-Seq_MESCs_Mouse1.80540869
26* SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.78552361
27E2F1_21310950_ChIP-Seq_MCF-7_Human1.76634467
28STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.76375859
29THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.73966473
30* NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.73667841
31IRF8_21731497_ChIP-ChIP_J774_Mouse1.67873356
32MYB_26560356_Chip-Seq_TH1_Human1.65825404
33RARG_19884340_ChIP-ChIP_MEFs_Mouse1.63086144
34KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.61786813
35KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.59488679
36LXR_22292898_ChIP-Seq_THP-1_Human1.59308386
37RACK7_27058665_Chip-Seq_MCF-7_Human1.59178957
38UTX_26944678_Chip-Seq_JUKART_Human1.59153932
39IRF8_27001747_Chip-Seq_BMDM_Mouse1.58684973
40* ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.57604299
41MYB_26560356_Chip-Seq_TH2_Human1.54177469
42MYC_19079543_ChIP-ChIP_MESCs_Mouse1.53360053
43KDM2B_26808549_Chip-Seq_DND41_Human1.52419934
44BRD4_27068464_Chip-Seq_AML-cells_Mouse1.51723432
45* P300_27058665_Chip-Seq_ZR-75-30cells_Human1.51015750
46SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.50635111
47EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.50482373
48CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.45657661
49Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.45251249
50HIF1A_21447827_ChIP-Seq_MCF-7_Human1.43688839
51KDM2B_26808549_Chip-Seq_JURKAT_Human1.42609547
52FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.42278692
53VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.41971835
54* RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.40615933
55AR_21909140_ChIP-Seq_LNCAP_Human1.39957555
56VDR_24763502_ChIP-Seq_THP-1_Human1.39452451
57ELK3_25401928_ChIP-Seq_HUVEC_Human1.38691353
58TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.38372303
59KDM2B_26808549_Chip-Seq_K562_Human1.32297998
60SPI1_23547873_ChIP-Seq_NB4_Human1.31373607
61RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.31251205
62* ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.31131386
63RUNX1_22412390_ChIP-Seq_EML_Mouse1.30945413
64SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.30785232
65SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.30343052
66SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.30255045
67ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.29265531
68* TFEB_21752829_ChIP-Seq_HELA_Human1.29162724
69TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.28264417
70KDM2B_26808549_Chip-Seq_SUP-B15_Human1.28064462
71STAT3_1855785_ChIP-Seq_MESCs_Mouse1.27016254
72GATA1_22383799_ChIP-Seq_G1ME_Mouse1.26510086
73SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.26477809
74ZNF263_19887448_ChIP-Seq_K562_Human1.25243922
75IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.22790510
76DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.22614302
77TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.20340883
78NANOG_18555785_ChIP-Seq_MESCs_Mouse1.19388102
79TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.18501950
80RUNX_20019798_ChIP-Seq_JUKART_Human1.17917721
81MYC_19030024_ChIP-ChIP_MESCs_Mouse1.17228657
82KDM5A_27292631_Chip-Seq_BREAST_Human1.16428431
83SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.16142324
84ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.15456184
85UBF1/2_26484160_Chip-Seq_HMECs_Human1.15000102
86KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.14740986
87NOTCH1_21737748_ChIP-Seq_TLL_Human1.14730180
88WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.13353910
89SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.12346595
90SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.12346595
91IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.10803774
92STAT4_19710469_ChIP-ChIP_TH1__Mouse1.10594344
93GATA2_22383799_ChIP-Seq_G1ME_Mouse1.09491179
94CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.08641912
95CIITA_25753668_ChIP-Seq_RAJI_Human1.08444994
96SALL1_21062744_ChIP-ChIP_HESCs_Human1.08208854
97DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.08102655
98NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.07547832
99NCOR1_26117541_ChIP-Seq_K562_Human1.07535089
100SPI1_23127762_ChIP-Seq_K562_Human1.07435442
101RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.05979472
102GATA1_19941827_ChIP-Seq_MEL_Mouse1.05641280
103ESR2_21235772_ChIP-Seq_MCF-7_Human1.05598577
104* ZFP281_27345836_Chip-Seq_ESCs_Mouse1.04578698
105NELFA_20434984_ChIP-Seq_ESCs_Mouse1.04276092
106POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.03898637
107TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.02821256
108ATF3_27146783_Chip-Seq_COLON_Human1.02777799
109E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.01953046
110MYCN_18555785_ChIP-Seq_MESCs_Mouse1.01532772
111TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.00750056
112SOX2_27498859_Chip-Seq_STOMACH_Mouse1.00625516
113* PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.00440392
114* MAF_26560356_Chip-Seq_TH2_Human1.00243675
115UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.99887106
116TCF3_18692474_ChIP-Seq_MEFs_Mouse0.99857775
117SOX2_18358816_ChIP-ChIP_MESCs_Mouse0.99674120
118PU_27001747_Chip-Seq_BMDM_Mouse0.99345327
119PKCTHETA_26484144_Chip-Seq_BREAST_Human0.98828418
120RUNX2_24764292_ChIP-Seq_MC3T3_Mouse0.98648314
121NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.98498005
122KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.98307005
123ZFP281_18757296_ChIP-ChIP_E14_Mouse0.97231889
124SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.97192512
125MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse0.96873688
126KLF4_18555785_ChIP-Seq_MESCs_Mouse0.96556204
127NKX2-5_21415370_ChIP-Seq_HL-1_Mouse0.96507301
128ELK1_19687146_ChIP-ChIP_HELA_Human0.96435987
129CLOCK_20551151_ChIP-Seq_293T_Human0.95324749
130TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.93826774
131NANOG_21062744_ChIP-ChIP_HESCs_Human0.93633036
132CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.93596313
133POU5F1_18555785_ChIP-Seq_MESCs_Mouse0.91932308
134* PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.90948446
135MYBL2_22936984_ChIP-ChIP_MESCs_Mouse0.90828182
136TP63_17297297_ChIP-ChIP_HaCaT_Human0.86577424
137FOXO3_23340844_ChIP-Seq_DLD1_Human0.85541691
138TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.84295543

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005451_abnormal_body_composition3.39619834
2MP0008057_abnormal_DNA_replication2.82167181
3MP0005076_abnormal_cell_differentiation2.62336222
4MP0003705_abnormal_hypodermis_morpholog2.56693856
5MP0010352_gastrointestinal_tract_polyps2.55849893
6MP0009278_abnormal_bone_marrow2.53396494
7MP0002877_abnormal_melanocyte_morpholog2.53062970
8MP0003303_peritoneal_inflammation2.29736556
9MP0002396_abnormal_hematopoietic_system2.16948450
10MP0003077_abnormal_cell_cycle2.15036225
11MP0010307_abnormal_tumor_latency2.12640154
12MP0005058_abnormal_lysosome_morphology2.00661833
13MP0004957_abnormal_blastocyst_morpholog1.97654497
14MP0003191_abnormal_cellular_cholesterol1.97384904
15MP0003828_pulmonary_edema1.96242149
16MP0010094_abnormal_chromosome_stability1.95690603
17MP0003453_abnormal_keratinocyte_physiol1.87142312
18MP0003111_abnormal_nucleus_morphology1.81586888
19MP0003436_decreased_susceptibility_to1.81215737
20MP0001545_abnormal_hematopoietic_system1.75319401
21MP0005397_hematopoietic_system_phenotyp1.75319401
22MP0001835_abnormal_antigen_presentation1.72632626
23MP0008260_abnormal_autophagy1.71724476
24MP0003300_gastrointestinal_ulcer1.71413621
25MP0000350_abnormal_cell_proliferation1.63778753
26MP0004233_abnormal_muscle_weight1.62764410
27MP0001800_abnormal_humoral_immune1.62257554
28MP0003984_embryonic_growth_retardation1.60599295
29MP0009840_abnormal_foam_cell1.60280617
30MP0002088_abnormal_embryonic_growth/wei1.60207493
31MP0008007_abnormal_cellular_replicative1.56593148
32MP0003656_abnormal_erythrocyte_physiolo1.55836577
33MP0000733_abnormal_muscle_development1.55814720
34MP0001672_abnormal_embryogenesis/_devel1.53234288
35MP0005380_embryogenesis_phenotype1.53234288
36MP0004808_abnormal_hematopoietic_stem1.52933490
37MP0003566_abnormal_cell_adhesion1.52930228
38MP0002398_abnormal_bone_marrow1.51242379
39MP0003448_altered_tumor_morphology1.50701082
40MP0002086_abnormal_extraembryonic_tissu1.49872615
41MP0003890_abnormal_embryonic-extraembry1.49775797
42MP0003172_abnormal_lysosome_physiology1.48037117
43MP0004197_abnormal_fetal_growth/weight/1.47849974
44MP0002452_abnormal_antigen_presenting1.44276368
45MP0003724_increased_susceptibility_to1.43524737
46MP0002405_respiratory_system_inflammati1.41888809
47MP0005000_abnormal_immune_tolerance1.40337138
48MP0005671_abnormal_response_to1.40233207
49MP0009333_abnormal_splenocyte_physiolog1.39846735
50MP0006082_CNS_inflammation1.39436653
51MP0000703_abnormal_thymus_morphology1.39276024
52MP0010234_abnormal_vibrissa_follicle1.38188324
53MP0002998_abnormal_bone_remodeling1.35650267
54MP0004264_abnormal_extraembryonic_tissu1.35176847
55MP0001533_abnormal_skeleton_physiology1.34458674
56MP0008438_abnormal_cutaneous_collagen1.33298980
57MP0005023_abnormal_wound_healing1.32253598
58MP0001730_embryonic_growth_arrest1.32126955
59MP0001697_abnormal_embryo_size1.30861970
60MP0002722_abnormal_immune_system1.29924888
61MP0001853_heart_inflammation1.28936421
62MP0004185_abnormal_adipocyte_glucose1.28763795
63MP0003763_abnormal_thymus_physiology1.27319255
64MP0000689_abnormal_spleen_morphology1.26901553
65MP0002723_abnormal_immune_serum1.25700392
66MP0010630_abnormal_cardiac_muscle1.24190742
67MP0000569_abnormal_digit_pigmentation1.23944808
68MP0002420_abnormal_adaptive_immunity1.23075331
69MP0005666_abnormal_adipose_tissue1.22500639
70MP0001819_abnormal_immune_cell1.21217062
71MP0005409_darkened_coat_color1.20750598
72MP0000716_abnormal_immune_system1.16734060
73MP0002084_abnormal_developmental_patter1.15405310
74MP0001790_abnormal_immune_system1.15226984
75MP0005387_immune_system_phenotype1.15226984
76MP0004510_myositis1.15210755
77MP0002796_impaired_skin_barrier1.15200913
78MP0002085_abnormal_embryonic_tissue1.11911663
79MP0000685_abnormal_immune_system1.11784137
80MP0000858_altered_metastatic_potential1.11426631
81MP0004947_skin_inflammation1.09896988
82MP0002419_abnormal_innate_immunity1.09324102
83MP0003693_abnormal_embryo_hatching1.08178824
84MP0008961_abnormal_basal_metabolism1.08054168
85MP0002429_abnormal_blood_cell1.07989404
86MP0001348_abnormal_lacrimal_gland1.07196294
87MP0003091_abnormal_cell_migration1.05836174
88MP0005464_abnormal_platelet_physiology1.05782077
89MP0005025_abnormal_response_to1.05466082
90MP0002925_abnormal_cardiovascular_devel1.05107233
91MP0005621_abnormal_cell_physiology1.04444359
92MP0010368_abnormal_lymphatic_system1.04244090
93MP0002019_abnormal_tumor_incidence1.02999341
94MP0001915_intracranial_hemorrhage1.02601743
95MP0003221_abnormal_cardiomyocyte_apopto1.02575790
96MP0003567_abnormal_fetal_cardiomyocyte1.02507998
97MP0000490_abnormal_crypts_of1.00536987
98MP0008058_abnormal_DNA_repair0.98733369
99MP0009053_abnormal_anal_canal0.98672226
100MP0002080_prenatal_lethality0.98641426
101MP0009785_altered_susceptibility_to0.98448152
102MP0002006_tumorigenesis0.97896254
103MP0002254_reproductive_system_inflammat0.97501512
104MP0001851_eye_inflammation0.97351178
105MP0000313_abnormal_cell_death0.95825881
106MP0001849_ear_inflammation0.94412854
107MP0001845_abnormal_inflammatory_respons0.92959350
108MP0000767_abnormal_smooth_muscle0.92723117
109MP0003279_aneurysm0.92487039
110MP0002933_joint_inflammation0.92252093
111MP0005375_adipose_tissue_phenotype0.90379451
112MP0009115_abnormal_fat_cell0.89980902
113MP0004084_abnormal_cardiac_muscle0.89828422
114MP0005257_abnormal_intraocular_pressure0.89307167
115MP0001216_abnormal_epidermal_layer0.89201517
116MP0002166_altered_tumor_susceptibility0.88614739
117MP0010030_abnormal_orbit_morphology0.87984756
118MP0009703_decreased_birth_body0.87742567
119MP0005501_abnormal_skin_physiology0.87081739
120MP0005164_abnormal_response_to0.87079055
121MP0000343_altered_response_to0.86260757
122MP0000750_abnormal_muscle_regeneration0.85856547
123MP0010155_abnormal_intestine_physiology0.85789872
124MP0000266_abnormal_heart_morphology0.84748442
125MP0002060_abnormal_skin_morphology0.83773984
126MP0002009_preneoplasia0.83595284
127MP0003950_abnormal_plasma_membrane0.83434879
128MP0008469_abnormal_protein_level0.82456832
129MP0002148_abnormal_hypersensitivity_rea0.79692508
130MP0002138_abnormal_hepatobiliary_system0.79660990
131MP0004858_abnormal_nervous_system0.78875903
132MP0001293_anophthalmia0.78299200
133MP0003045_fibrosis0.78120792
134MP0001873_stomach_inflammation0.77837943
135MP0009672_abnormal_birth_weight0.77516054
136MP0008932_abnormal_embryonic_tissue0.76355405

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of the fingertips (HP:0001211)3.17283386
2Chromsome breakage (HP:0040012)2.97364871
3Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.78384366
4Volvulus (HP:0002580)2.73547202
5Abnormality of macrophages (HP:0004311)2.69156296
6Chromosomal breakage induced by crosslinking agents (HP:0003221)2.67334292
7Ectopic kidney (HP:0000086)2.66503143
8Spinal muscular atrophy (HP:0007269)2.59153845
9Rectal prolapse (HP:0002035)2.57888261
10Intestinal fistula (HP:0100819)2.57289583
11Distal lower limb amyotrophy (HP:0008944)2.55365800
12Acute lymphatic leukemia (HP:0006721)2.44401664
13Centrally nucleated skeletal muscle fibers (HP:0003687)2.43904633
14Ependymoma (HP:0002888)2.42390807
15Mediastinal lymphadenopathy (HP:0100721)2.39331938
16Increased IgE level (HP:0003212)2.39308897
17Spinal cord lesions (HP:0100561)2.38415059
18Syringomyelia (HP:0003396)2.38415059
19Protrusio acetabuli (HP:0003179)2.37651453
20Spontaneous hematomas (HP:0007420)2.37605713
21Hyperacusis (HP:0010780)2.32910458
22Vertebral compression fractures (HP:0002953)2.32618465
23Eczematoid dermatitis (HP:0000976)2.31960842
24Fatigue (HP:0012378)2.29950335
25Short 4th metacarpal (HP:0010044)2.28755423
26Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.28755423
27Supernumerary ribs (HP:0005815)2.19320927
28Increased density of long bones (HP:0006392)2.16054289
29Macroorchidism (HP:0000053)2.15270087
30Cerebral aneurysm (HP:0004944)2.14683918
31Rhabdomyosarcoma (HP:0002859)2.13065364
32Urethral obstruction (HP:0000796)2.12541708
33Segmental peripheral demyelination/remyelination (HP:0003481)2.11995094
34Broad face (HP:0000283)2.10924906
35Orchitis (HP:0100796)2.10174612
36Clubbing of toes (HP:0100760)2.09922995
37Neoplasm of striated muscle (HP:0009728)2.08678771
38Long eyelashes (HP:0000527)2.07963444
39Elevated erythrocyte sedimentation rate (HP:0003565)2.07092715
40Osteolytic defects of the phalanges of the hand (HP:0009771)2.04721011
41Osteolytic defects of the hand bones (HP:0009699)2.04721011
42Flat acetabular roof (HP:0003180)2.04687485
43Hematochezia (HP:0002573)2.04550266
44Abnormality of skeletal muscle fiber size (HP:0012084)2.04192867
45Polycythemia (HP:0001901)2.01113953
46Persistence of primary teeth (HP:0006335)2.00326098
47Rectovaginal fistula (HP:0000143)1.99557249
48Rectal fistula (HP:0100590)1.99557249
49Recurrent abscess formation (HP:0002722)1.99238852
50Ankyloglossia (HP:0010296)1.99161964
51Acute myeloid leukemia (HP:0004808)1.98488727
52Abnormality of chromosome stability (HP:0003220)1.98025037
53Reticulocytopenia (HP:0001896)1.97809973
54Increased nuchal translucency (HP:0010880)1.96132428
55Deep venous thrombosis (HP:0002625)1.95025189
56T lymphocytopenia (HP:0005403)1.94914773
57Achilles tendon contracture (HP:0001771)1.94910129
58Gastrointestinal carcinoma (HP:0002672)1.94854352
59Malignant gastrointestinal tract tumors (HP:0006749)1.94854352
60Glioma (HP:0009733)1.93996454
61Increased connective tissue (HP:0009025)1.93769040
62Recurrent fungal infections (HP:0002841)1.92767786
63Abnormality of DNA repair (HP:0003254)1.92037975
64Abnormality of the nasal septum (HP:0000419)1.91911295
65Subacute progressive viral hepatitis (HP:0006572)1.91662219
66Gingivitis (HP:0000230)1.91520117
67Deviation of the thumb (HP:0009603)1.90935447
68Recurrent viral infections (HP:0004429)1.90456255
69Bladder neoplasm (HP:0009725)1.90127414
70Bladder carcinoma (HP:0002862)1.90127414
71Supernumerary bones of the axial skeleton (HP:0009144)1.90113090
72Increased variability in muscle fiber diameter (HP:0003557)1.89346131
73Aneurysm (HP:0002617)1.89055291
74Pustule (HP:0200039)1.89019555
75Basal cell carcinoma (HP:0002671)1.88533171
76Abnormality of the astrocytes (HP:0100707)1.88346479
77Astrocytoma (HP:0009592)1.88346479
78Arterial tortuosity (HP:0005116)1.88277941
79Cutaneous melanoma (HP:0012056)1.87953293
80Exercise-induced myalgia (HP:0003738)1.87686871
81Deep palmar crease (HP:0006191)1.87665983
82Absent thumb (HP:0009777)1.87604130
83Long palpebral fissure (HP:0000637)1.87351350
84Spondylolisthesis (HP:0003302)1.86427338
85Medulloblastoma (HP:0002885)1.86241840
86Meckel diverticulum (HP:0002245)1.85346097
87Hereditary nonpolyposis colorectal carcinoma (HP:0006716)1.84938895
88Abnormality of T cell number (HP:0011839)1.84749394
89Myelodysplasia (HP:0002863)1.84727766
90Proximal placement of thumb (HP:0009623)1.84530773
91Short 5th finger (HP:0009237)1.84153285
92Abnormality of the ileum (HP:0001549)1.82213741
93Abnormality of the carotid arteries (HP:0005344)1.80514080
94Limited elbow extension (HP:0001377)1.80424107
95Myocardial infarction (HP:0001658)1.80333803
96Rib fusion (HP:0000902)1.80300207
97Short humerus (HP:0005792)1.80147655
98Disproportionate tall stature (HP:0001519)1.79978234
99Emphysema (HP:0002097)1.79739690
100Broad palm (HP:0001169)1.79623573
101Aplasia/Hypoplasia of the uvula (HP:0010293)1.79220238
102Gastrointestinal stroma tumor (HP:0100723)1.78563015
103Uterine leiomyosarcoma (HP:0002891)1.78190676
104Leiomyosarcoma (HP:0100243)1.78190676
105Abnormality of the Achilles tendon (HP:0005109)1.77977301
106Distal lower limb muscle weakness (HP:0009053)1.77695757
107Prominent nose (HP:0000448)1.76950381
108Dilatation of the ascending aorta (HP:0005111)1.75768574
109Cellulitis (HP:0100658)1.75733341
110Recurrent gram-negative bacterial infections (HP:0005420)1.75538273
111Sparse lateral eyebrow (HP:0005338)1.75480338
112Obstructive sleep apnea (HP:0002870)1.75448108
113Premature rupture of membranes (HP:0001788)1.75153317
114Gastrointestinal infarctions (HP:0005244)1.74911066
115Depressed nasal tip (HP:0000437)1.74312225
116Aplasia/hypoplasia of the humerus (HP:0006507)1.74084970
117Poikiloderma (HP:0001029)1.74076791
118Recurrent bacterial skin infections (HP:0005406)1.73796116
119Aplasia/Hypoplasia of the 5th finger (HP:0006262)1.73672484
120Cutis marmorata (HP:0000965)1.73505776
121Retrobulbar optic neuritis (HP:0100654)1.73250645
122Optic neuritis (HP:0100653)1.73250645
123Abnormality of oral frenula (HP:0000190)1.73058036
124Skull defect (HP:0001362)1.72109186
125Ulnar bowing (HP:0003031)1.71894344
126Vasculitis (HP:0002633)1.71838650
127Vascular tortuosity (HP:0004948)1.71219195
128Abnormality of the thoracic spine (HP:0100711)1.70165892
129Broad thumb (HP:0011304)1.70092320
130Viral hepatitis (HP:0006562)1.70054409
131Ureteral obstruction (HP:0006000)1.69532150
132Transitional cell carcinoma of the bladder (HP:0006740)1.69173645
133Abnormality of the 4th metacarpal (HP:0010012)1.68614156
134Heterotopia (HP:0002282)1.67895668
135Myositis (HP:0100614)1.67527914
136Narrow palate (HP:0000189)1.67155566
137Peritonitis (HP:0002586)1.66908483
138Termporal pattern (HP:0011008)1.66394894
139Insidious onset (HP:0003587)1.66394894
140Agnosia (HP:0010524)1.66187841
141Hyperparathyroidism (HP:0000843)1.66002729
142Asymmetry of the thorax (HP:0001555)1.65821889
143Colitis (HP:0002583)1.65607118
144Anal stenosis (HP:0002025)1.65265089
145Chronic obstructive pulmonary disease (HP:0006510)1.64384483
146Obstructive lung disease (HP:0006536)1.64384483
147Selective tooth agenesis (HP:0001592)1.64199200
148Abnormality of glycolipid metabolism (HP:0010969)1.63372931
149Abnormality of liposaccharide metabolism (HP:0010968)1.63372931
150Abnormality of glycosphingolipid metabolism (HP:0004343)1.63372931
151Duplicated collecting system (HP:0000081)1.63191387
152Cafe-au-lait spot (HP:0000957)1.62636140
153Deep philtrum (HP:0002002)1.62579069
154Abnormality of the peritoneum (HP:0002585)1.62174987
155Mitral regurgitation (HP:0001653)1.61315292
156Abnormality of the left ventricular outflow tract (HP:0011103)1.61147364
157Subaortic stenosis (HP:0001682)1.61147364
158Upper limb amyotrophy (HP:0009129)1.60659396
159Distal upper limb amyotrophy (HP:0007149)1.60659396
160Skin tags (HP:0010609)1.60561118
161Vaginal fistula (HP:0004320)1.60503020
162Lower limb amyotrophy (HP:0007210)1.59801410
163Arterial thrombosis (HP:0004420)1.59783042
164Exostoses (HP:0100777)1.59441683
165Facial hemangioma (HP:0000329)1.59312987
166Coarse hair (HP:0002208)1.58570347
167Slow saccadic eye movements (HP:0000514)1.57773453
168Hemorrhage of the eye (HP:0011885)1.57426357
169Cervical subluxation (HP:0003308)1.56212633
170Metaphyseal cupping (HP:0003021)1.56106494
171Meningitis (HP:0001287)1.54614655
172Asymmetric septal hypertrophy (HP:0001670)1.54052094
173Gastrointestinal inflammation (HP:0004386)1.53488311
174Recurrent cutaneous fungal infections (HP:0011370)1.53191387
175Chronic mucocutaneous candidiasis (HP:0002728)1.53191387
176Aortic aneurysm (HP:0004942)1.52854405
177Urticaria (HP:0001025)1.52532859
178Interstitial pulmonary disease (HP:0006530)1.52410742
179Mitral valve prolapse (HP:0001634)1.51987403

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDK124.88678441
2PRPF4B3.80089215
3TRIB33.60507944
4IRAK32.96825163
5PKN22.56585411
6MAP3K102.52818575
7SMG12.33902112
8STK102.28453053
9EEF2K1.95091634
10BRSK21.90988536
11MAP4K11.90432539
12LATS11.87582188
13ERN11.76818178
14MAP3K131.76253447
15TXK1.70008470
16CDK61.62312413
17CDC71.54077703
18FLT31.53750099
19BRD41.53722602
20TTN1.53552675
21IRAK41.49079174
22JAK31.49047057
23KIT1.47329654
24SRPK11.46301877
25MAP3K141.43836125
26MARK31.43258657
27TAOK21.41931774
28CSF1R1.41100849
29MAP3K31.38390564
30KSR21.32568032
31TGFBR21.32249509
32FGFR31.27675548
33CAMK1D1.27190717
34STK31.26167277
35CDK41.25978083
36CHUK1.25249562
37LATS21.23328424
38DMPK1.22615718
39PIM11.21711521
40CDC42BPA1.21244031
41MAP3K11.17529904
42MST1R1.16816382
43MOS1.16055226
44LRRK21.15750308
45SIK21.14416532
46* MTOR1.12547964
47GRK61.10989435
48NEK21.09822854
49TAOK11.07855940
50ALK1.06922934
51TBK11.05310255
52RIPK11.05209295
53RPS6KA41.04568728
54CSK1.03760716
55IKBKB1.03522611
56RPS6KB21.01604480
57MAP2K31.00922096
58CAMK1G0.98128780
59SIK10.95530090
60IRAK20.94442677
61STK40.93970004
62CDK70.93418610
63PAK40.93099747
64ATR0.92152738
65SIK30.92107821
66YES10.90939518
67MELK0.90492709
68BMX0.89502214
69STK240.87653728
70ZAP700.86252621
71CHEK10.85762858
72MARK20.84650532
73NEK90.83830932
74PTK60.83779736
75MKNK20.81898567
76ICK0.80677794
77MKNK10.79958543
78PDGFRA0.79493364
79IRAK10.79216768
80TYK20.78694431
81CHEK20.78509066
82MAPK70.78490302
83HIPK20.77821834
84MAPK110.76051213
85MAP3K90.74869916
86PIM20.73772519
87TSSK60.73438525
88ATM0.73211467
89FGR0.73010272
90TRPM70.72463661
91WNK10.72050575
92PLK10.71925625
93PTK20.71892348
94MATK0.71689967
95EPHB10.69909285
96SGK30.67612849
97CDK90.67015704
98CDK80.65824892
99JAK20.65273181
100PAK20.64959056
101BLK0.64690464
102DYRK1B0.63802395
103PDPK10.63402257
104CDK20.62260410
105MAP3K20.62092670
106HCK0.61308152
107NME20.61009797
108JAK10.60988170
109LCK0.60810818
110EPHA20.60403131
111TAOK30.59383770
112KSR10.59331417
113MAP3K70.58344441
114MAPKAPK20.57390720
115PDGFRB0.57043379
116PRKD20.57002719
117AURKB0.56893571
118IKBKE0.56395767
119TYRO30.56244672
120RIPK40.55938032
121ITK0.55913224
122SCYL20.54570730
123WEE10.54404146
124RPS6KA60.53092616
125TTK0.52932868
126DDR20.52780977
127CLK10.51414287
128BRAF0.48515806
129EIF2AK10.48363044
130MAPK120.47537423
131MAP3K80.46362970
132PDK10.46342927
133FGFR40.45515304
134PLK30.45336144
135MAPK10.44975467
136BTK0.43675728
137MAP3K60.43652929
138ILK0.42595753
139RPS6KA10.42443297
140RET0.42385085
141MAP3K50.42212997
142AKT20.41224373
143EGFR0.40706975
144NUAK10.39822595

Predicted pathways (KEGG)

RankGene SetZ-score
1Butirosin and neomycin biosynthesis_Homo sapiens_hsa005242.18104773
2Leishmaniasis_Homo sapiens_hsa051402.02073519
3Antigen processing and presentation_Homo sapiens_hsa046121.92579331
4NF-kappa B signaling pathway_Homo sapiens_hsa040641.82261797
5Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.73131307
6B cell receptor signaling pathway_Homo sapiens_hsa046621.73107165
7Graft-versus-host disease_Homo sapiens_hsa053321.72559149
8One carbon pool by folate_Homo sapiens_hsa006701.71926807
9Osteoclast differentiation_Homo sapiens_hsa043801.69034823
10Herpes simplex infection_Homo sapiens_hsa051681.67012177
11Chronic myeloid leukemia_Homo sapiens_hsa052201.62007524
12RNA transport_Homo sapiens_hsa030131.58739914
13Acute myeloid leukemia_Homo sapiens_hsa052211.58535566
14Bladder cancer_Homo sapiens_hsa052191.58380273
15Cell cycle_Homo sapiens_hsa041101.58209230
16Measles_Homo sapiens_hsa051621.55067720
17Lysine degradation_Homo sapiens_hsa003101.54971906
18Viral myocarditis_Homo sapiens_hsa054161.52518765
19Spliceosome_Homo sapiens_hsa030401.52241338
20Small cell lung cancer_Homo sapiens_hsa052221.51778422
21MicroRNAs in cancer_Homo sapiens_hsa052061.51073327
22Other glycan degradation_Homo sapiens_hsa005111.50839625
23mTOR signaling pathway_Homo sapiens_hsa041501.42402819
24Allograft rejection_Homo sapiens_hsa053301.41847277
25Mismatch repair_Homo sapiens_hsa034301.40876523
26Toxoplasmosis_Homo sapiens_hsa051451.40761871
27mRNA surveillance pathway_Homo sapiens_hsa030151.40298171
28Adherens junction_Homo sapiens_hsa045201.39904293
29Primary immunodeficiency_Homo sapiens_hsa053401.38244920
30DNA replication_Homo sapiens_hsa030301.36593422
31T cell receptor signaling pathway_Homo sapiens_hsa046601.36247846
32Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.35643455
33Base excision repair_Homo sapiens_hsa034101.34793450
34NOD-like receptor signaling pathway_Homo sapiens_hsa046211.33136971
35Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.33068951
36Toll-like receptor signaling pathway_Homo sapiens_hsa046201.30122378
37Legionellosis_Homo sapiens_hsa051341.29927530
38HTLV-I infection_Homo sapiens_hsa051661.29179046
39Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.26788460
40Apoptosis_Homo sapiens_hsa042101.26407059
41Transcriptional misregulation in cancer_Homo sapiens_hsa052021.25947244
42Notch signaling pathway_Homo sapiens_hsa043301.24241993
43TNF signaling pathway_Homo sapiens_hsa046681.23696468
44AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.23456620
45Influenza A_Homo sapiens_hsa051641.20170941
46Hepatitis B_Homo sapiens_hsa051611.19834928
47Jak-STAT signaling pathway_Homo sapiens_hsa046301.19733895
48Fanconi anemia pathway_Homo sapiens_hsa034601.19197032
49Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.18840723
50p53 signaling pathway_Homo sapiens_hsa041151.16112735
51Epstein-Barr virus infection_Homo sapiens_hsa051691.15484130
52Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.14655865
53Pancreatic cancer_Homo sapiens_hsa052121.12136011
54Prion diseases_Homo sapiens_hsa050201.11622087
55Hematopoietic cell lineage_Homo sapiens_hsa046401.10320410
56Proteoglycans in cancer_Homo sapiens_hsa052051.08944530
57ErbB signaling pathway_Homo sapiens_hsa040121.08908629
58Tuberculosis_Homo sapiens_hsa051521.07660750
59Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.06490763
60Leukocyte transendothelial migration_Homo sapiens_hsa046701.05780241
61Colorectal cancer_Homo sapiens_hsa052101.04443984
62Viral carcinogenesis_Homo sapiens_hsa052031.02149625
63RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.01131267
64Shigellosis_Homo sapiens_hsa051311.00110984
65Neurotrophin signaling pathway_Homo sapiens_hsa047220.99970423
66Staphylococcus aureus infection_Homo sapiens_hsa051500.99144016
67* RNA degradation_Homo sapiens_hsa030180.98112309
68Insulin signaling pathway_Homo sapiens_hsa049100.97790103
69Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.97561090
70TGF-beta signaling pathway_Homo sapiens_hsa043500.97492450
71Glioma_Homo sapiens_hsa052140.97328629
72Malaria_Homo sapiens_hsa051440.96035757
73Homologous recombination_Homo sapiens_hsa034400.92125410
74Platelet activation_Homo sapiens_hsa046110.91745728
75Adipocytokine signaling pathway_Homo sapiens_hsa049200.88467304
76Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.88070367
77Focal adhesion_Homo sapiens_hsa045100.86592022
78Non-homologous end-joining_Homo sapiens_hsa034500.84478351
79Thyroid hormone signaling pathway_Homo sapiens_hsa049190.84309691
80HIF-1 signaling pathway_Homo sapiens_hsa040660.83713428
81Nucleotide excision repair_Homo sapiens_hsa034200.83194964
82Glycosaminoglycan degradation_Homo sapiens_hsa005310.80708285
83Insulin resistance_Homo sapiens_hsa049310.80237257
84Amoebiasis_Homo sapiens_hsa051460.79580758
85Prostate cancer_Homo sapiens_hsa052150.79418281
86Intestinal immune network for IgA production_Homo sapiens_hsa046720.79125175
87Chemokine signaling pathway_Homo sapiens_hsa040620.76633261
88Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.75076251
89GnRH signaling pathway_Homo sapiens_hsa049120.73005174
90Regulation of actin cytoskeleton_Homo sapiens_hsa048100.72783187
91Type I diabetes mellitus_Homo sapiens_hsa049400.72203920
92Pathways in cancer_Homo sapiens_hsa052000.71374839
93Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.70910597
94Choline metabolism in cancer_Homo sapiens_hsa052310.70040695
95Sphingolipid signaling pathway_Homo sapiens_hsa040710.70007674
96VEGF signaling pathway_Homo sapiens_hsa043700.69835457
97Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.69799653
98Non-small cell lung cancer_Homo sapiens_hsa052230.69657529
99Pertussis_Homo sapiens_hsa051330.69228111
100Phospholipase D signaling pathway_Homo sapiens_hsa040720.69088453
101Prolactin signaling pathway_Homo sapiens_hsa049170.67987994
102Longevity regulating pathway - mammal_Homo sapiens_hsa042110.67858116
103Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.67708317
104Pentose phosphate pathway_Homo sapiens_hsa000300.66081581
105Lysosome_Homo sapiens_hsa041420.65825755
106Renal cell carcinoma_Homo sapiens_hsa052110.65463486
107Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.65353664
108Endocytosis_Homo sapiens_hsa041440.65228241
109Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.64890693
110Inositol phosphate metabolism_Homo sapiens_hsa005620.64436168
111Phosphatidylinositol signaling system_Homo sapiens_hsa040700.64253879
112Thyroid cancer_Homo sapiens_hsa052160.64165371
113FoxO signaling pathway_Homo sapiens_hsa040680.64137090
114Central carbon metabolism in cancer_Homo sapiens_hsa052300.64047999
115Estrogen signaling pathway_Homo sapiens_hsa049150.61888293
116Salmonella infection_Homo sapiens_hsa051320.61614449
117Phagosome_Homo sapiens_hsa041450.60787922
118Hippo signaling pathway_Homo sapiens_hsa043900.60429388
119Endometrial cancer_Homo sapiens_hsa052130.59198287
120Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.58947869
121African trypanosomiasis_Homo sapiens_hsa051430.57948975
122Dorso-ventral axis formation_Homo sapiens_hsa043200.56943483
123Hepatitis C_Homo sapiens_hsa051600.56254337
124Autoimmune thyroid disease_Homo sapiens_hsa053200.55944050
125AMPK signaling pathway_Homo sapiens_hsa041520.54881044
126Asthma_Homo sapiens_hsa053100.54652694
127MAPK signaling pathway_Homo sapiens_hsa040100.51885725

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »