Rank | Gene Set | Z-score |
---|---|---|
1 | COPI coating of Golgi vesicle (GO:0048205) | 7.34419112 |
2 | Golgi transport vesicle coating (GO:0048200) | 7.34419112 |
3 | endocrine pancreas development (GO:0031018) | 7.25701456 |
4 | negative regulation of pathway-restricted SMAD protein phosphorylation (GO:0060394) | 6.20676311 |
5 | regulation of type B pancreatic cell apoptotic process (GO:2000674) | 5.94803368 |
6 | artery development (GO:0060840) | 5.83161322 |
7 | receptor catabolic process (GO:0032801) | 5.30429906 |
8 | keratinocyte development (GO:0003334) | 5.28725179 |
9 | peptide hormone processing (GO:0016486) | 5.21534429 |
10 | * glandular epithelial cell differentiation (GO:0002067) | 5.15875258 |
11 | positive regulation of insulin secretion (GO:0032024) | 5.09218774 |
12 | type B pancreatic cell development (GO:0003323) | 5.05810592 |
13 | insulin secretion (GO:0030073) | 4.70327132 |
14 | regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (GO:1902235 | 4.60161943 |
15 | maintenance of protein localization in endoplasmic reticulum (GO:0035437) | 4.57411790 |
16 | embryonic foregut morphogenesis (GO:0048617) | 4.47805640 |
17 | exocrine pancreas development (GO:0031017) | 4.43895304 |
18 | negative regulation of dendrite morphogenesis (GO:0050774) | 4.37070129 |
19 | epithelial cell fate commitment (GO:0072148) | 4.33225248 |
20 | signal peptide processing (GO:0006465) | 4.32287419 |
21 | retrograde vesicle-mediated transport, Golgi to ER (GO:0006890) | 4.31524668 |
22 | regulation of insulin secretion (GO:0050796) | 4.30168454 |
23 | gastrulation with mouth forming second (GO:0001702) | 4.22752578 |
24 | protein maturation by protein folding (GO:0022417) | 4.22318470 |
25 | negative regulation of glial cell proliferation (GO:0060253) | 4.17773116 |
26 | COPII vesicle coating (GO:0048208) | 4.04550719 |
27 | histone H3-K9 methylation (GO:0051567) | 4.01944481 |
28 | response to pheromone (GO:0019236) | 4.01111897 |
29 | myelin assembly (GO:0032288) | 3.99848357 |
30 | positive regulation of peptide hormone secretion (GO:0090277) | 3.99356683 |
31 | negative regulation of intracellular estrogen receptor signaling pathway (GO:0033147) | 3.97215284 |
32 | regulation of gene expression by genetic imprinting (GO:0006349) | 3.95821836 |
33 | regulation of peptide hormone secretion (GO:0090276) | 3.94098906 |
34 | protein retention in ER lumen (GO:0006621) | 3.90876723 |
35 | regulation of peptide secretion (GO:0002791) | 3.86492906 |
36 | positive regulation of peptide secretion (GO:0002793) | 3.86027319 |
37 | ER overload response (GO:0006983) | 3.85394474 |
38 | negative regulation of cytosolic calcium ion concentration (GO:0051481) | 3.81763901 |
39 | nitric oxide mediated signal transduction (GO:0007263) | 3.81568674 |
40 | estrogen biosynthetic process (GO:0006703) | 3.78299982 |
41 | negative regulation of dendrite development (GO:2000171) | 3.78172655 |
42 | limb bud formation (GO:0060174) | 3.76374150 |
43 | sequestering of metal ion (GO:0051238) | 3.75316401 |
44 | pre-miRNA processing (GO:0031054) | 3.72462598 |
45 | detection of calcium ion (GO:0005513) | 3.63797305 |
46 | cilium morphogenesis (GO:0060271) | 3.62075753 |
47 | peptide hormone secretion (GO:0030072) | 3.60958397 |
48 | photoreceptor cell maintenance (GO:0045494) | 3.58485993 |
49 | RNA destabilization (GO:0050779) | 3.56056250 |
50 | lymphangiogenesis (GO:0001946) | 3.54717487 |
51 | regulation of hormone secretion (GO:0046883) | 3.53061992 |
52 | genetic imprinting (GO:0071514) | 3.51495317 |
53 | * glandular epithelial cell development (GO:0002068) | 3.51335430 |
54 | peptide secretion (GO:0002790) | 3.50142847 |
55 | cell proliferation in forebrain (GO:0021846) | 3.49853885 |
56 | appendage development (GO:0048736) | 3.48853329 |
57 | limb development (GO:0060173) | 3.48853329 |
58 | positive regulation of insulin secretion involved in cellular response to glucose stimulus (GO:00357 | 3.42915877 |
59 | pancreas development (GO:0031016) | 3.42346627 |
60 | cardiac ventricle formation (GO:0003211) | 3.40197219 |
61 | negative regulation of norepinephrine secretion (GO:0010700) | 3.34673698 |
62 | regulation of glucocorticoid secretion (GO:2000849) | 3.34505739 |
63 | positive regulation of actin filament depolymerization (GO:0030836) | 3.32802237 |
64 | activation of signaling protein activity involved in unfolded protein response (GO:0006987) | 3.31424714 |
65 | cranial nerve development (GO:0021545) | 3.31319237 |
66 | heparan sulfate proteoglycan metabolic process (GO:0030201) | 3.28487659 |
67 | negative regulation of catecholamine secretion (GO:0033604) | 3.27417541 |
68 | mannose metabolic process (GO:0006013) | 3.25640344 |
69 | regulation of insulin secretion involved in cellular response to glucose stimulus (GO:0061178) | 3.25327581 |
70 | positive regulation of hormone secretion (GO:0046887) | 3.24847988 |
71 | presynaptic membrane assembly (GO:0097105) | 3.24583945 |
72 | pharyngeal system development (GO:0060037) | 3.23904710 |
73 | negative regulation of insulin secretion (GO:0046676) | 3.22483317 |
74 | neuron fate specification (GO:0048665) | 3.19992401 |
75 | intraciliary transport (GO:0042073) | 3.19926062 |
76 | protein targeting to Golgi (GO:0000042) | 3.19359840 |
77 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 3.18338812 |
78 | glycerophospholipid catabolic process (GO:0046475) | 3.17708113 |
79 | intra-Golgi vesicle-mediated transport (GO:0006891) | 3.16150310 |
80 | secondary heart field specification (GO:0003139) | 3.14864008 |
81 | heart field specification (GO:0003128) | 3.14864008 |
82 | establishment of protein localization to Golgi (GO:0072600) | 3.14322853 |
83 | positive regulation of nuclease activity (GO:0032075) | 3.14198247 |
84 | regulation of peptide transport (GO:0090087) | 3.12276320 |
85 | specification of organ identity (GO:0010092) | 3.11022951 |
86 | cardiac chamber formation (GO:0003207) | 3.10889160 |
87 | macroautophagy (GO:0016236) | 3.09783816 |
88 | substrate-independent telencephalic tangential interneuron migration (GO:0021843) | 3.08534434 |
89 | substrate-independent telencephalic tangential migration (GO:0021826) | 3.08534434 |
90 | histone H3-K9 modification (GO:0061647) | 3.06618330 |
91 | vesicle coating (GO:0006901) | 3.06485013 |
92 | protein localization to Golgi apparatus (GO:0034067) | 3.05883790 |
93 | intestinal epithelial cell development (GO:0060576) | 3.04756880 |
94 | histone H2A monoubiquitination (GO:0035518) | 3.04622679 |
95 | cellular response to vitamin D (GO:0071305) | 3.02892781 |
96 | positive regulation of neurological system process (GO:0031646) | 3.02698015 |
97 | peptidyl-lysine trimethylation (GO:0018023) | 3.01608901 |
98 | nonmotile primary cilium assembly (GO:0035058) | 3.01004889 |
99 | synapsis (GO:0007129) | 3.00915992 |
100 | postsynaptic membrane organization (GO:0001941) | 2.98364454 |
101 | dentate gyrus development (GO:0021542) | 2.98294610 |
102 | chemosensory behavior (GO:0007635) | 2.96680999 |
103 | GMP metabolic process (GO:0046037) | 2.95920426 |
104 | glial cell proliferation (GO:0014009) | 2.94910484 |
105 | regulation of glucokinase activity (GO:0033131) | 2.94594483 |
106 | regulation of hexokinase activity (GO:1903299) | 2.94594483 |
107 | * columnar/cuboidal epithelial cell development (GO:0002066) | 2.93539518 |
108 | somite development (GO:0061053) | 2.93099830 |
109 | negative regulation of JUN kinase activity (GO:0043508) | 2.92908566 |
110 | hormone secretion (GO:0046879) | 2.92901584 |
111 | cellular response to ATP (GO:0071318) | 2.92720218 |
112 | toxin metabolic process (GO:0009404) | 2.92023055 |
113 | retrograde transport, vesicle recycling within Golgi (GO:0000301) | 2.90593881 |
114 | neuron fate determination (GO:0048664) | 2.89493441 |
115 | inner ear receptor cell development (GO:0060119) | 2.89457672 |
116 | retinal ganglion cell axon guidance (GO:0031290) | 2.88932944 |
117 | regulation of nuclease activity (GO:0032069) | 2.88464961 |
118 | negative regulation of glycoprotein biosynthetic process (GO:0010561) | 2.86372815 |
119 | regulation of autophagic vacuole assembly (GO:2000785) | 2.86220659 |
120 | positive regulation of synaptic transmission, dopaminergic (GO:0032226) | 2.86117397 |
121 | positive regulation of TOR signaling (GO:0032008) | 2.85798133 |
122 | presynaptic membrane organization (GO:0097090) | 2.85142365 |
123 | spinal cord motor neuron differentiation (GO:0021522) | 2.83650463 |
124 | histone H2A acetylation (GO:0043968) | 2.83056116 |
125 | olfactory bulb development (GO:0021772) | 2.82812640 |
126 | peptide transport (GO:0015833) | 2.82749611 |
127 | negative regulation of peptide hormone secretion (GO:0090278) | 2.81510071 |
128 | nucleoside diphosphate catabolic process (GO:0009134) | 2.80238055 |
129 | magnesium ion transport (GO:0015693) | 2.79331927 |
130 | positive regulation of DNA-templated transcription, initiation (GO:2000144) | 2.78197894 |
131 | protein prenylation (GO:0018342) | 2.77778457 |
132 | prenylation (GO:0097354) | 2.77778457 |
133 | neural tube formation (GO:0001841) | 2.76623273 |
134 | male sex determination (GO:0030238) | 2.75582114 |
135 | oocyte development (GO:0048599) | 2.75099280 |
136 | cellular response to unfolded protein (GO:0034620) | 2.74601115 |
137 | axonal fasciculation (GO:0007413) | 2.74176233 |
138 | cellular response to virus (GO:0098586) | 2.73879274 |
139 | regulation of oligodendrocyte differentiation (GO:0048713) | 2.73104134 |
140 | endoplasmic reticulum unfolded protein response (GO:0030968) | 2.72701625 |
141 | hormone transport (GO:0009914) | 2.72312296 |
142 | regulation of calcium ion-dependent exocytosis (GO:0017158) | 2.71655433 |
143 | cerebellar Purkinje cell layer development (GO:0021680) | 2.71195108 |
144 | regulation of neurotransmitter uptake (GO:0051580) | 2.70304836 |
145 | microtubule anchoring (GO:0034453) | 2.69683522 |
146 | negative regulation of peptide secretion (GO:0002792) | 2.68760525 |
147 | mitochondrion degradation (GO:0000422) | 2.68589910 |
148 | cellular response to topologically incorrect protein (GO:0035967) | 2.68193004 |
149 | histone H2A ubiquitination (GO:0033522) | 2.68144540 |
150 | protein N-linked glycosylation via asparagine (GO:0018279) | 2.67594536 |
151 | dendritic spine morphogenesis (GO:0060997) | 2.67113747 |
152 | ER-associated ubiquitin-dependent protein catabolic process (GO:0030433) | 2.66974105 |
153 | negative regulation of osteoblast proliferation (GO:0033689) | 2.66933147 |
154 | water-soluble vitamin biosynthetic process (GO:0042364) | 2.66009742 |
155 | regulation of corticosteroid hormone secretion (GO:2000846) | 2.65760950 |
156 | negative regulation of translation involved in gene silencing by miRNA (GO:0035278) | 2.64329468 |
157 | negative regulation of translation, ncRNA-mediated (GO:0040033) | 2.64329468 |
158 | regulation of translation, ncRNA-mediated (GO:0045974) | 2.64329468 |
159 | peptidyl-asparagine modification (GO:0018196) | 2.64224730 |
160 | * positive regulation of neuroblast proliferation (GO:0002052) | 2.64208568 |
161 | glucose catabolic process (GO:0006007) | 2.63377821 |
162 | * photoreceptor cell development (GO:0042461) | 2.63365551 |
163 | epithelial cilium movement (GO:0003351) | 2.61785575 |
164 | positive regulation of gluconeogenesis (GO:0045722) | 2.61736671 |
165 | cellular response to hepatocyte growth factor stimulus (GO:0035729) | 2.61345561 |
166 | response to hepatocyte growth factor (GO:0035728) | 2.61345561 |
167 | ER-nucleus signaling pathway (GO:0006984) | 2.60694737 |
168 | eye photoreceptor cell differentiation (GO:0001754) | 2.60658464 |
169 | photoreceptor cell differentiation (GO:0046530) | 2.60658464 |
170 | organ growth (GO:0035265) | 2.60534823 |
171 | parental behavior (GO:0060746) | 2.58972118 |
172 | establishment of nucleus localization (GO:0040023) | 2.58085880 |
173 | ear development (GO:0043583) | 2.58059148 |
174 | regulation of cardioblast proliferation (GO:0003264) | 2.57940100 |
175 | regulation of secondary heart field cardioblast proliferation (GO:0003266) | 2.57940100 |
176 | embryonic epithelial tube formation (GO:0001838) | 2.57704429 |
177 | GDP-mannose metabolic process (GO:0019673) | 2.56459206 |
178 | * columnar/cuboidal epithelial cell differentiation (GO:0002065) | 2.56298515 |
Rank | Gene Set | Z-score |
---|---|---|
1 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 5.05266824 |
2 | EZH2_22144423_ChIP-Seq_EOC_Human | 3.75417866 |
3 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 2.89354409 |
4 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.82205402 |
5 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.64324261 |
6 | AHR_22903824_ChIP-Seq_MCF-7_Human | 2.60748872 |
7 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 2.59341045 |
8 | REST_21632747_ChIP-Seq_MESCs_Mouse | 2.25787987 |
9 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 2.25419157 |
10 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.19373175 |
11 | * EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.17165583 |
12 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.12828686 |
13 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.10597373 |
14 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 2.00947597 |
15 | * CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.99421954 |
16 | FUS_26573619_Chip-Seq_HEK293_Human | 1.98662240 |
17 | * EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.97056845 |
18 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.95178087 |
19 | * SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.95043799 |
20 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.94792630 |
21 | * JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.90122810 |
22 | * MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.90080439 |
23 | * OLIG2_26023283_ChIP-Seq_AINV15_Mouse | 1.84952255 |
24 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.84788956 |
25 | * SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.78537939 |
26 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.77830082 |
27 | * SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 1.77136328 |
28 | * JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.76389082 |
29 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.75982732 |
30 | * SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.74510982 |
31 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.71609314 |
32 | * RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.69875805 |
33 | VDR_22108803_ChIP-Seq_LS180_Human | 1.69730966 |
34 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.68997631 |
35 | * SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.68289693 |
36 | * EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.67933232 |
37 | * SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.66878563 |
38 | * PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.63490485 |
39 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.63216173 |
40 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.61168366 |
41 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.59978740 |
42 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.57081505 |
43 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.53618056 |
44 | * HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 1.52636260 |
45 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.52017157 |
46 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.52017157 |
47 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.50631281 |
48 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.50571778 |
49 | AR_25329375_ChIP-Seq_VCAP_Human | 1.46878049 |
50 | * MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.46180062 |
51 | * STAT3_23295773_ChIP-Seq_U87_Human | 1.44821550 |
52 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.44650290 |
53 | * SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.43991461 |
54 | * POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.41680922 |
55 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.41492449 |
56 | EWS_26573619_Chip-Seq_HEK293_Human | 1.39552224 |
57 | * RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.38225172 |
58 | * EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.38225172 |
59 | * NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.36292679 |
60 | * RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.35103345 |
61 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.33824168 |
62 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.33048120 |
63 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.33048120 |
64 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.32001660 |
65 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 1.31205206 |
66 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.30973126 |
67 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 1.30909474 |
68 | * SMAD4_21799915_ChIP-Seq_A2780_Human | 1.30288255 |
69 | * MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.30274119 |
70 | * EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.29851713 |
71 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.28348123 |
72 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.27868075 |
73 | * PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.27564089 |
74 | GATA1_22025678_ChIP-Seq_K562_Human | 1.27442885 |
75 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.25254093 |
76 | LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.23430329 |
77 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.22961445 |
78 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.22929435 |
79 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.22451812 |
80 | PKCTHETA_26484144_Chip-Seq_BREAST_Human | 1.22398139 |
81 | P300_19829295_ChIP-Seq_ESCs_Human | 1.21365534 |
82 | * TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.21120916 |
83 | YAP1_20516196_ChIP-Seq_MESCs_Mouse | 1.20680345 |
84 | * STAT3_18555785_Chip-Seq_ESCs_Mouse | 1.20219110 |
85 | * NMYC_18555785_Chip-Seq_ESCs_Mouse | 1.19760833 |
86 | * P53_22387025_ChIP-Seq_ESCs_Mouse | 1.19517214 |
87 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.18171842 |
88 | CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse | 1.18153405 |
89 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 1.18036049 |
90 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.17081049 |
91 | TCF4_23295773_ChIP-Seq_U87_Human | 1.16443442 |
92 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.16394288 |
93 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.15430090 |
94 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.13792386 |
95 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.13359719 |
96 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.12802229 |
97 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.12494681 |
98 | RXR_22108803_ChIP-Seq_LS180_Human | 1.12433537 |
99 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 1.12214909 |
100 | * SMAD4_21741376_ChIP-Seq_EPCs_Human | 1.11573697 |
101 | TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse | 1.11510584 |
102 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.10815751 |
103 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.10727039 |
104 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.09673672 |
105 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.09114320 |
106 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.09102498 |
107 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.08398775 |
108 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.08209092 |
109 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.08208174 |
110 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.08076568 |
111 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.07879771 |
112 | REST_19997604_ChIP-ChIP_NEURONS_Mouse | 1.06591168 |
113 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.06263579 |
114 | * SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 1.05780862 |
115 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 1.05697477 |
116 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.05331731 |
117 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 1.04634112 |
118 | * RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.03941666 |
119 | * SOX2_18555785_Chip-Seq_ESCs_Mouse | 1.03855314 |
120 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.03441393 |
121 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.02383817 |
122 | * TBL1_22424771_ChIP-Seq_293T_Human | 1.02068454 |
123 | * SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.01746655 |
124 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 1.01369295 |
125 | * AR_19668381_ChIP-Seq_PC3_Human | 1.00891917 |
126 | SMAD3_21741376_ChIP-Seq_ESCs_Human | 1.00463951 |
127 | * SUZ12_18555785_Chip-Seq_ESCs_Mouse | 0.99266855 |
128 | * CMYC_18555785_Chip-Seq_ESCs_Mouse | 0.98973503 |
129 | * E2F1_18555785_Chip-Seq_ESCs_Mouse | 0.98963816 |
130 | * RING1B_27294783_Chip-Seq_NPCs_Mouse | 0.98264306 |
131 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 0.97373527 |
132 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.96979424 |
133 | GF1B_26923725_Chip-Seq_HPCs_Mouse | 0.95869662 |
134 | * ESRRB_18555785_Chip-Seq_ESCs_Mouse | 0.95048807 |
135 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.94688019 |
136 | * P300_18555785_Chip-Seq_ESCs_Mouse | 0.93410495 |
137 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 0.93220234 |
138 | NFIB_24661679_ChIP-Seq_LUNG_Mouse | 0.92575065 |
139 | * ZFX_18555785_Chip-Seq_ESCs_Mouse | 0.90734364 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0008877_abnormal_DNA_methylation | 5.38972771 |
2 | MP0006072_abnormal_retinal_apoptosis | 3.88627187 |
3 | MP0002877_abnormal_melanocyte_morpholog | 3.86496381 |
4 | MP0003283_abnormal_digestive_organ | 3.75559137 |
5 | * MP0002693_abnormal_pancreas_physiology | 3.45917744 |
6 | * MP0001944_abnormal_pancreas_morphology | 3.39800920 |
7 | MP0000678_abnormal_parathyroid_gland | 3.37403581 |
8 | MP0004043_abnormal_pH_regulation | 3.37032027 |
9 | MP0005379_endocrine/exocrine_gland_phen | 3.26430899 |
10 | MP0009780_abnormal_chondrocyte_physiolo | 3.16074649 |
11 | MP0002909_abnormal_adrenal_gland | 3.11709654 |
12 | MP0003183_abnormal_peptide_metabolism | 3.09481252 |
13 | MP0000013_abnormal_adipose_tissue | 3.09151691 |
14 | MP0010386_abnormal_urinary_bladder | 2.86619372 |
15 | MP0005220_abnormal_exocrine_pancreas | 2.68003260 |
16 | MP0003195_calcinosis | 2.62959992 |
17 | MP0005645_abnormal_hypothalamus_physiol | 2.59213234 |
18 | MP0002160_abnormal_reproductive_system | 2.59141770 |
19 | MP0005646_abnormal_pituitary_gland | 2.59057970 |
20 | MP0001986_abnormal_taste_sensitivity | 2.53926352 |
21 | MP0005253_abnormal_eye_physiology | 2.52173755 |
22 | MP0009046_muscle_twitch | 2.44752878 |
23 | MP0000631_abnormal_neuroendocrine_gland | 2.15996553 |
24 | MP0000383_abnormal_hair_follicle | 2.13049201 |
25 | MP0005551_abnormal_eye_electrophysiolog | 2.12409759 |
26 | MP0008057_abnormal_DNA_replication | 2.11937941 |
27 | MP0010678_abnormal_skin_adnexa | 2.09260021 |
28 | MP0010234_abnormal_vibrissa_follicle | 1.92077787 |
29 | MP0002102_abnormal_ear_morphology | 1.84745623 |
30 | MP0004133_heterotaxia | 1.84684564 |
31 | MP0001502_abnormal_circadian_rhythm | 1.80891237 |
32 | MP0001919_abnormal_reproductive_system | 1.79254807 |
33 | * MP0002078_abnormal_glucose_homeostasis | 1.71826050 |
34 | MP0002928_abnormal_bile_duct | 1.70528609 |
35 | MP0002234_abnormal_pharynx_morphology | 1.66960705 |
36 | MP0005389_reproductive_system_phenotype | 1.60423711 |
37 | MP0003122_maternal_imprinting | 1.60170381 |
38 | MP0004270_analgesia | 1.57726887 |
39 | MP0002837_dystrophic_cardiac_calcinosis | 1.54034618 |
40 | MP0000003_abnormal_adipose_tissue | 1.52262565 |
41 | MP0001188_hyperpigmentation | 1.50793103 |
42 | MP0002163_abnormal_gland_morphology | 1.50419302 |
43 | MP0003136_yellow_coat_color | 1.47959357 |
44 | * MP0002938_white_spotting | 1.47922287 |
45 | MP0003787_abnormal_imprinting | 1.45991223 |
46 | MP0001984_abnormal_olfaction | 1.41526298 |
47 | MP0002751_abnormal_autonomic_nervous | 1.39845922 |
48 | * MP0006292_abnormal_olfactory_placode | 1.37724062 |
49 | MP0001270_distended_abdomen | 1.32950835 |
50 | * MP0002638_abnormal_pupillary_reflex | 1.31852393 |
51 | MP0000049_abnormal_middle_ear | 1.30733864 |
52 | MP0009745_abnormal_behavioral_response | 1.30644074 |
53 | MP0003890_abnormal_embryonic-extraembry | 1.29421155 |
54 | MP0005410_abnormal_fertilization | 1.27157844 |
55 | MP0000462_abnormal_digestive_system | 1.26414590 |
56 | MP0002896_abnormal_bone_mineralization | 1.23985833 |
57 | MP0003119_abnormal_digestive_system | 1.22631073 |
58 | MP0002557_abnormal_social/conspecific_i | 1.18707602 |
59 | MP0003880_abnormal_central_pattern | 1.17750607 |
60 | MP0003938_abnormal_ear_development | 1.17383097 |
61 | MP0002064_seizures | 1.16063146 |
62 | MP0002653_abnormal_ependyma_morphology | 1.15685739 |
63 | MP0000681_abnormal_thyroid_gland | 1.14611463 |
64 | MP0003937_abnormal_limbs/digits/tail_de | 1.14329679 |
65 | * MP0005391_vision/eye_phenotype | 1.13696077 |
66 | * MP0003953_abnormal_hormone_level | 1.13101696 |
67 | MP0002734_abnormal_mechanical_nocicepti | 1.12244364 |
68 | MP0002184_abnormal_innervation | 1.10655393 |
69 | MP0003868_abnormal_feces_composition | 1.07981974 |
70 | MP0001765_abnormal_ion_homeostasis | 1.05727008 |
71 | MP0000566_synostosis | 1.05015839 |
72 | MP0002009_preneoplasia | 1.02661357 |
73 | MP0002233_abnormal_nose_morphology | 1.02410858 |
74 | MP0004264_abnormal_extraembryonic_tissu | 1.02174419 |
75 | MP0004885_abnormal_endolymph | 1.00361026 |
76 | MP0002063_abnormal_learning/memory/cond | 0.98902133 |
77 | MP0001501_abnormal_sleep_pattern | 0.98861957 |
78 | MP0002876_abnormal_thyroid_physiology | 0.98481689 |
79 | * MP0002177_abnormal_outer_ear | 0.98339958 |
80 | MP0002229_neurodegeneration | 0.97565265 |
81 | MP0003879_abnormal_hair_cell | 0.97280200 |
82 | MP0003011_delayed_dark_adaptation | 0.97159876 |
83 | MP0003959_abnormal_lean_body | 0.96788609 |
84 | MP0003941_abnormal_skin_development | 0.94198793 |
85 | MP0005248_abnormal_Harderian_gland | 0.93963363 |
86 | MP0004924_abnormal_behavior | 0.93826613 |
87 | MP0005386_behavior/neurological_phenoty | 0.93826613 |
88 | * MP0008789_abnormal_olfactory_epithelium | 0.92697756 |
89 | MP0008961_abnormal_basal_metabolism | 0.91857313 |
90 | * MP0000428_abnormal_craniofacial_morphol | 0.90870601 |
91 | MP0005187_abnormal_penis_morphology | 0.88581628 |
92 | * MP0000613_abnormal_salivary_gland | 0.88051488 |
93 | MP0002272_abnormal_nervous_system | 0.87761690 |
94 | MP0002735_abnormal_chemical_nociception | 0.86419131 |
95 | MP0005448_abnormal_energy_balance | 0.85528256 |
96 | * MP0005195_abnormal_posterior_eye | 0.85474389 |
97 | MP0003123_paternal_imprinting | 0.85355396 |
98 | MP0003172_abnormal_lysosome_physiology | 0.84714670 |
99 | MP0003633_abnormal_nervous_system | 0.84634507 |
100 | MP0003137_abnormal_impulse_conducting | 0.84208800 |
101 | MP0001293_anophthalmia | 0.84163077 |
102 | MP0006276_abnormal_autonomic_nervous | 0.83699824 |
103 | MP0009053_abnormal_anal_canal | 0.82485211 |
104 | MP0000647_abnormal_sebaceous_gland | 0.82479148 |
105 | MP0001968_abnormal_touch/_nociception | 0.82291537 |
106 | * MP0002882_abnormal_neuron_morphology | 0.82108583 |
107 | * MP0005394_taste/olfaction_phenotype | 0.80983844 |
108 | * MP0005499_abnormal_olfactory_system | 0.80983844 |
109 | MP0002822_catalepsy | 0.80769130 |
110 | MP0004145_abnormal_muscle_electrophysio | 0.79146446 |
111 | MP0000026_abnormal_inner_ear | 0.78647078 |
112 | MP0000015_abnormal_ear_pigmentation | 0.78448797 |
113 | MP0005367_renal/urinary_system_phenotyp | 0.77908354 |
114 | MP0000516_abnormal_urinary_system | 0.77908354 |
115 | MP0001299_abnormal_eye_distance/ | 0.77487554 |
116 | MP0008569_lethality_at_weaning | 0.77398864 |
117 | MP0005409_darkened_coat_color | 0.77022018 |
118 | MP0004859_abnormal_synaptic_plasticity | 0.77021295 |
119 | MP0001346_abnormal_lacrimal_gland | 0.76237346 |
120 | MP0002733_abnormal_thermal_nociception | 0.75269644 |
121 | * MP0000955_abnormal_spinal_cord | 0.74502553 |
122 | MP0001485_abnormal_pinna_reflex | 0.74174551 |
123 | MP0002069_abnormal_eating/drinking_beha | 0.74054383 |
124 | MP0002067_abnormal_sensory_capabilities | 0.73770936 |
125 | MP0001970_abnormal_pain_threshold | 0.73283226 |
126 | MP0005423_abnormal_somatic_nervous | 0.72631959 |
127 | * MP0000778_abnormal_nervous_system | 0.71809941 |
128 | MP0000538_abnormal_urinary_bladder | 0.71127808 |
129 | * MP0001324_abnormal_eye_pigmentation | 0.71109112 |
130 | MP0002090_abnormal_vision | 0.71108736 |
131 | MP0002572_abnormal_emotion/affect_behav | 0.70676089 |
132 | MP0003635_abnormal_synaptic_transmissio | 0.70257790 |
133 | MP0005310_abnormal_salivary_gland | 0.70092074 |
134 | * MP0002752_abnormal_somatic_nervous | 0.69344293 |
135 | MP0001486_abnormal_startle_reflex | 0.68032660 |
136 | * MP0003755_abnormal_palate_morphology | 0.66971047 |
137 | MP0003121_genomic_imprinting | 0.66239019 |
138 | MP0005535_abnormal_body_temperature | 0.66056947 |
139 | * MP0002116_abnormal_craniofacial_bone | 0.65287782 |
140 | MP0002277_abnormal_respiratory_mucosa | 0.64884326 |
141 | MP0004742_abnormal_vestibular_system | 0.64792340 |
142 | MP0001664_abnormal_digestion | 0.64156995 |
143 | MP0005084_abnormal_gallbladder_morpholo | 0.62397592 |
144 | MP0009672_abnormal_birth_weight | 0.59839843 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Hyperinsulinemic hypoglycemia (HP:0000825) | 6.86995051 |
2 | Hypoglycemic seizures (HP:0002173) | 6.56370419 |
3 | Elevated circulating parathyroid hormone (PTH) level (HP:0003165) | 6.17702642 |
4 | Symptomatic seizures (HP:0011145) | 6.15133666 |
5 | Difficulty running (HP:0009046) | 6.06204531 |
6 | Abnormality of calcium-phosphate metabolism (HP:0100530) | 4.91904924 |
7 | Hyperglycemia (HP:0003074) | 4.77640730 |
8 | Abnormality of the aortic arch (HP:0012303) | 4.73867047 |
9 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 4.59851446 |
10 | Hypoglycemic coma (HP:0001325) | 4.59092499 |
11 | Insulin-resistant diabetes mellitus (HP:0000831) | 4.58753175 |
12 | Osteomalacia (HP:0002749) | 4.11772095 |
13 | Abnormal rod and cone electroretinograms (HP:0008323) | 3.97050608 |
14 | Abnormality of endocrine pancreas physiology (HP:0012093) | 3.91638549 |
15 | Abnormality of the pancreatic islet cells (HP:0006476) | 3.91638549 |
16 | Pancreatic islet-cell hyperplasia (HP:0004510) | 3.87141097 |
17 | Large for gestational age (HP:0001520) | 3.78037853 |
18 | Hip dysplasia (HP:0001385) | 3.76112022 |
19 | Decreased circulating renin level (HP:0003351) | 3.73059986 |
20 | Hip contracture (HP:0003273) | 3.71340162 |
21 | Agitation (HP:0000713) | 3.70301892 |
22 | Aqueductal stenosis (HP:0002410) | 3.47471272 |
23 | Abnormal pancreas size (HP:0012094) | 3.41013490 |
24 | Late onset (HP:0003584) | 3.36313551 |
25 | Intestinal atresia (HP:0011100) | 3.30522438 |
26 | Ketoacidosis (HP:0001993) | 3.14903641 |
27 | Bony spicule pigmentary retinopathy (HP:0007737) | 3.09264702 |
28 | Congenital malformation of the right heart (HP:0011723) | 3.07824802 |
29 | Double outlet right ventricle (HP:0001719) | 3.07824802 |
30 | Abnormality of the metopic suture (HP:0005556) | 3.04563037 |
31 | Prominent metopic ridge (HP:0005487) | 3.02554701 |
32 | Hypokalemia (HP:0002900) | 2.99561058 |
33 | Hyperparathyroidism (HP:0000843) | 2.93294760 |
34 | Oligodactyly (hands) (HP:0001180) | 2.91302213 |
35 | Limb dystonia (HP:0002451) | 2.89727323 |
36 | Biliary tract neoplasm (HP:0100574) | 2.88809563 |
37 | Congenital stationary night blindness (HP:0007642) | 2.84881270 |
38 | Retinal atrophy (HP:0001105) | 2.83867410 |
39 | Limited hip movement (HP:0008800) | 2.75765622 |
40 | Attenuation of retinal blood vessels (HP:0007843) | 2.73829429 |
41 | Decreased central vision (HP:0007663) | 2.73706362 |
42 | Type II diabetes mellitus (HP:0005978) | 2.71441951 |
43 | Severe visual impairment (HP:0001141) | 2.71205561 |
44 | Unilateral renal agenesis (HP:0000122) | 2.66296747 |
45 | Congenital sensorineural hearing impairment (HP:0008527) | 2.65406569 |
46 | Hypothermia (HP:0002045) | 2.64327295 |
47 | Neoplasm of the adrenal cortex (HP:0100641) | 2.62286173 |
48 | Type I transferrin isoform profile (HP:0003642) | 2.60170610 |
49 | Oligodactyly (HP:0012165) | 2.56805072 |
50 | Abnormality of renin-angiotensin system (HP:0000847) | 2.56199764 |
51 | Nephronophthisis (HP:0000090) | 2.51954471 |
52 | Hyperventilation (HP:0002883) | 2.49509234 |
53 | Achilles tendon contracture (HP:0001771) | 2.46605547 |
54 | Pendular nystagmus (HP:0012043) | 2.44311540 |
55 | Abnormality of potassium homeostasis (HP:0011042) | 2.44204064 |
56 | Abnormal protein glycosylation (HP:0012346) | 2.43090713 |
57 | Abnormal glycosylation (HP:0012345) | 2.43090713 |
58 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.43090713 |
59 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.43090713 |
60 | Insulin resistance (HP:0000855) | 2.42632334 |
61 | Hyperphosphatemia (HP:0002905) | 2.39352283 |
62 | True hermaphroditism (HP:0010459) | 2.37704096 |
63 | EEG with generalized epileptiform discharges (HP:0011198) | 2.36659978 |
64 | Gait imbalance (HP:0002141) | 2.35198204 |
65 | Abnormality of the Achilles tendon (HP:0005109) | 2.34473675 |
66 | Gastrointestinal atresia (HP:0002589) | 2.33913404 |
67 | Hypsarrhythmia (HP:0002521) | 2.32952015 |
68 | Broad-based gait (HP:0002136) | 2.30487039 |
69 | Conjugated hyperbilirubinemia (HP:0002908) | 2.29282059 |
70 | Urinary glycosaminoglycan excretion (HP:0003541) | 2.28910283 |
71 | Mucopolysacchariduria (HP:0008155) | 2.28910283 |
72 | Hemiparesis (HP:0001269) | 2.28093879 |
73 | Epileptiform EEG discharges (HP:0011182) | 2.27062589 |
74 | Cystic liver disease (HP:0006706) | 2.25876961 |
75 | Abnormality of the labia minora (HP:0012880) | 2.25287868 |
76 | Adrenal hypoplasia (HP:0000835) | 2.23883805 |
77 | Thyroiditis (HP:0100646) | 2.23358222 |
78 | Restlessness (HP:0000711) | 2.22789125 |
79 | Hyperkalemia (HP:0002153) | 2.21743963 |
80 | Abnormality of mucopolysaccharide metabolism (HP:0011020) | 2.20773684 |
81 | Abnormality of polysaccharide metabolism (HP:0011012) | 2.20773684 |
82 | Abnormality of glycosaminoglycan metabolism (HP:0004371) | 2.20773684 |
83 | Pancreatic fibrosis (HP:0100732) | 2.20240463 |
84 | Tetraplegia (HP:0002445) | 2.19932256 |
85 | Abnormality of the renal cortex (HP:0011035) | 2.19048820 |
86 | Methylmalonic acidemia (HP:0002912) | 2.17674959 |
87 | Enlarged penis (HP:0000040) | 2.16359956 |
88 | Central scotoma (HP:0000603) | 2.14566654 |
89 | Hyperactive renin-angiotensin system (HP:0000841) | 2.13204209 |
90 | Pancreatic cysts (HP:0001737) | 2.12829720 |
91 | Exocrine pancreatic insufficiency (HP:0001738) | 2.12798531 |
92 | Congenital primary aphakia (HP:0007707) | 2.09777628 |
93 | Cortical visual impairment (HP:0100704) | 2.06068045 |
94 | Growth hormone deficiency (HP:0000824) | 2.05626523 |
95 | Abolished electroretinogram (ERG) (HP:0000550) | 2.05319905 |
96 | Abnormality of macular pigmentation (HP:0008002) | 2.04290640 |
97 | Esophageal atresia (HP:0002032) | 2.03290942 |
98 | Anophthalmia (HP:0000528) | 2.01395403 |
99 | Abnormality of cochlea (HP:0000375) | 2.01380767 |
100 | Aplasia/hypoplasia of the uterus (HP:0008684) | 2.00712700 |
101 | Dysostosis multiplex (HP:0000943) | 2.00691321 |
102 | Constricted visual fields (HP:0001133) | 2.00367082 |
103 | Abnormality of the renal medulla (HP:0100957) | 1.98329810 |
104 | * Hypoplasia of the fovea (HP:0007750) | 1.96465545 |
105 | * Aplasia/Hypoplasia of the fovea (HP:0008060) | 1.96465545 |
106 | Large eyes (HP:0001090) | 1.95473494 |
107 | Dysautonomia (HP:0002459) | 1.94834951 |
108 | Abnormal biliary tract morphology (HP:0012440) | 1.94674177 |
109 | Generalized aminoaciduria (HP:0002909) | 1.94179497 |
110 | Anteriorly placed anus (HP:0001545) | 1.92644077 |
111 | Absent eyebrow (HP:0002223) | 1.91708911 |
112 | Rhabdomyosarcoma (HP:0002859) | 1.90858220 |
113 | Septo-optic dysplasia (HP:0100842) | 1.89901632 |
114 | Atrioventricular canal defect (HP:0006695) | 1.88923159 |
115 | Renal cortical cysts (HP:0000803) | 1.88040172 |
116 | Increased CSF protein (HP:0002922) | 1.86953052 |
117 | Hypomagnesemia (HP:0002917) | 1.86262400 |
118 | Retinitis pigmentosa (HP:0000510) | 1.85750905 |
119 | Menstrual irregularities (HP:0000858) | 1.85542833 |
120 | Split foot (HP:0001839) | 1.84749642 |
121 | Abnormality of vitamin B metabolism (HP:0004340) | 1.84203127 |
122 | Hypercortisolism (HP:0001578) | 1.83339472 |
123 | Molar tooth sign on MRI (HP:0002419) | 1.83036683 |
124 | Abnormality of midbrain morphology (HP:0002418) | 1.83036683 |
125 | Nephrogenic diabetes insipidus (HP:0009806) | 1.82744558 |
126 | Abnormal drinking behavior (HP:0030082) | 1.81875056 |
127 | Polydipsia (HP:0001959) | 1.81875056 |
128 | Status epilepticus (HP:0002133) | 1.81513061 |
129 | Sex reversal (HP:0012245) | 1.80758559 |
130 | Abnormal sex determination (HP:0012244) | 1.80758559 |
131 | Visual hallucinations (HP:0002367) | 1.79866132 |
132 | Diastasis recti (HP:0001540) | 1.78508498 |
133 | Adrenal overactivity (HP:0002717) | 1.77782281 |
134 | Labial hypoplasia (HP:0000066) | 1.75598969 |
135 | Chronic hepatic failure (HP:0100626) | 1.75458048 |
136 | Ketosis (HP:0001946) | 1.75197466 |
137 | Abnormality of chloride homeostasis (HP:0011422) | 1.73989077 |
138 | Photophobia (HP:0000613) | 1.73672903 |
139 | Thyroid carcinoma (HP:0002890) | 1.72850706 |
140 | Hyperaldosteronism (HP:0000859) | 1.72225090 |
141 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 1.71788827 |
142 | Short 4th metacarpal (HP:0010044) | 1.71788827 |
143 | Bifid tongue (HP:0010297) | 1.70756592 |
144 | Overlapping toe (HP:0001845) | 1.69509664 |
145 | Poor coordination (HP:0002370) | 1.69252900 |
146 | Progressive neurologic deterioration (HP:0002344) | 1.68999803 |
147 | Posterior subcapsular cataract (HP:0007787) | 1.68202024 |
148 | Progressive cerebellar ataxia (HP:0002073) | 1.68091292 |
149 | Medial flaring of the eyebrow (HP:0010747) | 1.67797805 |
150 | Renal dysplasia (HP:0000110) | 1.67786397 |
151 | Enlarged kidneys (HP:0000105) | 1.67627270 |
152 | Genital tract atresia (HP:0001827) | 1.66422758 |
153 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 1.66294851 |
154 | Abnormality of the parathyroid morphology (HP:0011766) | 1.66251869 |
155 | Hypophosphatemia (HP:0002148) | 1.65957871 |
156 | Hepatoblastoma (HP:0002884) | 1.65646726 |
157 | Type II lissencephaly (HP:0007260) | 1.65400009 |
158 | Median cleft lip (HP:0000161) | 1.63014491 |
159 | Atelectasis (HP:0100750) | 1.61899664 |
160 | Papillary thyroid carcinoma (HP:0002895) | 1.60549617 |
161 | Scotoma (HP:0000575) | 1.59837670 |
162 | Abnormality of magnesium homeostasis (HP:0004921) | 1.58491289 |
163 | Abdominal distention (HP:0003270) | 1.58331798 |
Rank | Gene Set | Z-score |
---|---|---|
1 | INSRR | 7.19471017 |
2 | PTK2B | 4.98917686 |
3 | MAPK15 | 4.93501382 |
4 | PASK | 4.32045926 |
5 | WNK3 | 3.27592972 |
6 | TAOK3 | 2.99193148 |
7 | TNIK | 2.46032047 |
8 | WEE1 | 2.44617319 |
9 | FGFR2 | 2.30763619 |
10 | UHMK1 | 2.21377443 |
11 | CASK | 2.05720668 |
12 | * HIPK2 | 2.03603232 |
13 | PRKD3 | 1.96735830 |
14 | BRSK2 | 1.91291505 |
15 | MAP3K2 | 1.84352317 |
16 | IRAK2 | 1.78207755 |
17 | MAP3K4 | 1.76929963 |
18 | DYRK1B | 1.69752850 |
19 | IRAK3 | 1.69561206 |
20 | FRK | 1.68872937 |
21 | MAP4K2 | 1.64978050 |
22 | IRAK1 | 1.63255809 |
23 | NTRK3 | 1.62393176 |
24 | WNK4 | 1.54553733 |
25 | PRKD2 | 1.45907150 |
26 | STK16 | 1.40094264 |
27 | PHKG2 | 1.38116703 |
28 | PHKG1 | 1.38116703 |
29 | PIK3CG | 1.36082846 |
30 | CAMKK2 | 1.34048159 |
31 | CDC42BPA | 1.33243949 |
32 | MKNK2 | 1.31084532 |
33 | ACVR1B | 1.27088791 |
34 | EIF2AK3 | 1.26104817 |
35 | STK3 | 1.26086922 |
36 | STK24 | 1.23300246 |
37 | NLK | 1.20678277 |
38 | PAK6 | 1.20444497 |
39 | AKT3 | 1.18037675 |
40 | CSNK1G1 | 1.13494962 |
41 | MAP3K1 | 1.05701213 |
42 | RPS6KB2 | 1.05672269 |
43 | DYRK3 | 1.05326156 |
44 | PLK2 | 1.05029156 |
45 | EPHA3 | 1.04039207 |
46 | BMPR1B | 1.00665541 |
47 | BRD4 | 0.98735172 |
48 | CSNK1G3 | 0.95367343 |
49 | NEK6 | 0.95198907 |
50 | PRKCG | 0.94154710 |
51 | SIK3 | 0.92911150 |
52 | CDK19 | 0.91265540 |
53 | IRAK4 | 0.90673495 |
54 | SGK2 | 0.89988478 |
55 | DYRK1A | 0.88938157 |
56 | MAP3K9 | 0.88814902 |
57 | GRK1 | 0.87739215 |
58 | SGK223 | 0.86702184 |
59 | SGK494 | 0.86702184 |
60 | CSNK1G2 | 0.85420133 |
61 | VRK1 | 0.84928829 |
62 | NUAK1 | 0.83494719 |
63 | WNK1 | 0.82245492 |
64 | EPHA4 | 0.79962883 |
65 | OXSR1 | 0.79374580 |
66 | FLT3 | 0.76620954 |
67 | YES1 | 0.76571597 |
68 | PRKCH | 0.76266287 |
69 | MAPK13 | 0.76069985 |
70 | CDK3 | 0.75371301 |
71 | DAPK2 | 0.75255442 |
72 | MAPK7 | 0.73723731 |
73 | STK11 | 0.72514791 |
74 | TLK1 | 0.72428326 |
75 | SRPK1 | 0.72061921 |
76 | KSR2 | 0.71016638 |
77 | VRK2 | 0.69638625 |
78 | ERBB3 | 0.68435386 |
79 | DYRK2 | 0.68008060 |
80 | ADRBK2 | 0.67735402 |
81 | TYRO3 | 0.66513947 |
82 | BRSK1 | 0.66316450 |
83 | PIK3CA | 0.65842354 |
84 | PNCK | 0.64939962 |
85 | MAP2K2 | 0.64623853 |
86 | PAK3 | 0.64073215 |
87 | PRKCE | 0.63949515 |
88 | ZAK | 0.62896851 |
89 | SIK1 | 0.62113037 |
90 | MAP2K7 | 0.62105760 |
91 | BCR | 0.62013097 |
92 | PTK6 | 0.59098047 |
93 | PRKAA1 | 0.59073695 |
94 | BCKDK | 0.57784607 |
95 | MARK1 | 0.57640945 |
96 | PTK2 | 0.56832224 |
97 | TEC | 0.55644439 |
98 | FER | 0.54304321 |
99 | MUSK | 0.54281985 |
100 | KSR1 | 0.53348645 |
101 | MARK2 | 0.52718452 |
102 | BMPR2 | 0.51061628 |
103 | NTRK1 | 0.49770565 |
104 | PINK1 | 0.48826275 |
105 | PDGFRA | 0.48590638 |
106 | MAP2K1 | 0.48343002 |
107 | STK39 | 0.47960324 |
108 | CSNK1D | 0.47244821 |
109 | TAOK1 | 0.45780428 |
110 | EPHB2 | 0.45577054 |
111 | CSNK1A1 | 0.44999952 |
112 | LATS1 | 0.44492733 |
113 | CAMK2D | 0.44491879 |
114 | PRKCZ | 0.42713923 |
115 | PRKDC | 0.42126031 |
116 | RPS6KA2 | 0.40356559 |
117 | CSNK1A1L | 0.39818893 |
118 | NTRK2 | 0.39781820 |
119 | MAPK14 | 0.39354270 |
120 | RAF1 | 0.38840353 |
121 | RPS6KB1 | 0.38659616 |
122 | SGK1 | 0.38108295 |
123 | PRKACA | 0.38028595 |
124 | ITK | 0.37285774 |
125 | PKN1 | 0.37127136 |
126 | TRPM7 | 0.37040827 |
127 | PRKCI | 0.36424007 |
128 | CAMK2B | 0.36096696 |
129 | PRKG1 | 0.35435035 |
130 | GSK3A | 0.34201166 |
131 | PRKAA2 | 0.33709459 |
132 | AKT1 | 0.33608412 |
133 | CAMK1G | 0.33088512 |
134 | BRAF | 0.32424627 |
135 | CHUK | 0.32310861 |
136 | MAP2K4 | 0.32147395 |
137 | GSK3B | 0.31850980 |
138 | SGK3 | 0.31233074 |
139 | PLK3 | 0.30459156 |
140 | PRKD1 | 0.30300025 |
141 | ADRBK1 | 0.30204989 |
142 | ERN1 | 0.29584656 |
143 | STK38L | 0.29331316 |
144 | ERBB2 | 0.29286325 |
145 | MAP2K6 | 0.28898921 |
146 | CDK5 | 0.28488181 |
147 | CSNK1E | 0.27139588 |
Rank | Gene Set | Z-score |
---|---|---|
1 | * Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 8.47597706 |
2 | Protein export_Homo sapiens_hsa03060 | 4.93104578 |
3 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 3.74889826 |
4 | Insulin secretion_Homo sapiens_hsa04911 | 3.34010996 |
5 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 2.56676731 |
6 | Phototransduction_Homo sapiens_hsa04744 | 2.47962140 |
7 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 2.41340416 |
8 | Sulfur metabolism_Homo sapiens_hsa00920 | 2.33925207 |
9 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 2.23381859 |
10 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.16874056 |
11 | Steroid biosynthesis_Homo sapiens_hsa00100 | 2.14230044 |
12 | Butanoate metabolism_Homo sapiens_hsa00650 | 2.08754375 |
13 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.88461399 |
14 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 1.78120471 |
15 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 1.70335435 |
16 | Circadian rhythm_Homo sapiens_hsa04710 | 1.68994529 |
17 | Taste transduction_Homo sapiens_hsa04742 | 1.67812625 |
18 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 1.66059590 |
19 | Cocaine addiction_Homo sapiens_hsa05030 | 1.63374053 |
20 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 1.58889770 |
21 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.57441250 |
22 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.52899608 |
23 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.36712390 |
24 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 1.36281553 |
25 | Amphetamine addiction_Homo sapiens_hsa05031 | 1.27182629 |
26 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.25879445 |
27 | GABAergic synapse_Homo sapiens_hsa04727 | 1.25313378 |
28 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.22117444 |
29 | Pancreatic secretion_Homo sapiens_hsa04972 | 1.22065271 |
30 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.21567993 |
31 | Circadian entrainment_Homo sapiens_hsa04713 | 1.14982635 |
32 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 1.13763654 |
33 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.12505603 |
34 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.10603468 |
35 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 1.10046023 |
36 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.06127356 |
37 | Other glycan degradation_Homo sapiens_hsa00511 | 1.04081719 |
38 | Morphine addiction_Homo sapiens_hsa05032 | 1.03672886 |
39 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.03374594 |
40 | Dopaminergic synapse_Homo sapiens_hsa04728 | 1.03211509 |
41 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.01799291 |
42 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.99341765 |
43 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.97626882 |
44 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.94905954 |
45 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.94868261 |
46 | Lysosome_Homo sapiens_hsa04142 | 0.94572153 |
47 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.93009398 |
48 | ABC transporters_Homo sapiens_hsa02010 | 0.92778936 |
49 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.92029141 |
50 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.90559917 |
51 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.90534027 |
52 | Alcoholism_Homo sapiens_hsa05034 | 0.87821156 |
53 | * Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.87750736 |
54 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.82614782 |
55 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.80599694 |
56 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.78988560 |
57 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.77531450 |
58 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.76353129 |
59 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.76212617 |
60 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.76032549 |
61 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.75668134 |
62 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.75531111 |
63 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.75290787 |
64 | Long-term potentiation_Homo sapiens_hsa04720 | 0.74961275 |
65 | RNA degradation_Homo sapiens_hsa03018 | 0.74427873 |
66 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.73752350 |
67 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.72873389 |
68 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.71160510 |
69 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.71051353 |
70 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.70980761 |
71 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.70976745 |
72 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.70879145 |
73 | Nicotine addiction_Homo sapiens_hsa05033 | 0.67924105 |
74 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.67291314 |
75 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.66215355 |
76 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.65970574 |
77 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.65304038 |
78 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.65281124 |
79 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.65215377 |
80 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.65047014 |
81 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.64208026 |
82 | Bile secretion_Homo sapiens_hsa04976 | 0.63740866 |
83 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.63026534 |
84 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.61107143 |
85 | Mineral absorption_Homo sapiens_hsa04978 | 0.60219108 |
86 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.59599088 |
87 | Insulin resistance_Homo sapiens_hsa04931 | 0.58948269 |
88 | Retinol metabolism_Homo sapiens_hsa00830 | 0.56601457 |
89 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.56276608 |
90 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.55993671 |
91 | Peroxisome_Homo sapiens_hsa04146 | 0.53122941 |
92 | Renin secretion_Homo sapiens_hsa04924 | 0.51694087 |
93 | Long-term depression_Homo sapiens_hsa04730 | 0.51310995 |
94 | Prion diseases_Homo sapiens_hsa05020 | 0.50009268 |
95 | Melanogenesis_Homo sapiens_hsa04916 | 0.49859123 |
96 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.49839687 |
97 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.47761527 |
98 | Prostate cancer_Homo sapiens_hsa05215 | 0.47404476 |
99 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.47368232 |
100 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.46582279 |
101 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.45694657 |
102 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.45320962 |
103 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.45138784 |
104 | Metabolic pathways_Homo sapiens_hsa01100 | 0.45010463 |
105 | Lysine degradation_Homo sapiens_hsa00310 | 0.43853664 |
106 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.42035931 |
107 | Endometrial cancer_Homo sapiens_hsa05213 | 0.40400530 |
108 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.39984350 |
109 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.39793029 |
110 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.39755302 |
111 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.38416219 |
112 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.38123235 |
113 | Thyroid cancer_Homo sapiens_hsa05216 | 0.37192710 |
114 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.37185417 |
115 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.36882025 |
116 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.36661628 |
117 | Olfactory transduction_Homo sapiens_hsa04740 | 0.36641664 |
118 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.34815306 |
119 | Galactose metabolism_Homo sapiens_hsa00052 | 0.34342376 |
120 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.34061442 |
121 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.32203607 |
122 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.30505894 |
123 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.28936831 |
124 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.28443219 |
125 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.27544745 |
126 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.27117947 |
127 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.27058406 |
128 | Basal transcription factors_Homo sapiens_hsa03022 | 0.26331756 |
129 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.22734992 |
130 | Gap junction_Homo sapiens_hsa04540 | 0.22723127 |
131 | Salivary secretion_Homo sapiens_hsa04970 | 0.22650326 |
132 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.22149311 |
133 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.21078073 |
134 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.19853508 |
135 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.19825000 |
136 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.19664273 |
137 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.19100626 |
138 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.18359936 |
139 | Axon guidance_Homo sapiens_hsa04360 | 0.17828558 |
140 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.16169016 |