PBX3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1establishment of mitochondrion localization (GO:0051654)5.05048941
2presynaptic membrane organization (GO:0097090)4.84663847
3behavioral response to nicotine (GO:0035095)4.55485665
4neuron cell-cell adhesion (GO:0007158)4.53103635
5dendritic spine morphogenesis (GO:0060997)4.14011257
6protein localization to synapse (GO:0035418)4.09519657
7establishment of mitochondrion localization, microtubule-mediated (GO:0034643)3.96947716
8mitochondrion transport along microtubule (GO:0047497)3.96947716
9pyrimidine nucleobase catabolic process (GO:0006208)3.93177111
10neuron recognition (GO:0008038)3.80634498
11negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.78425919
12layer formation in cerebral cortex (GO:0021819)3.77524808
13ionotropic glutamate receptor signaling pathway (GO:0035235)3.74901759
14axonal fasciculation (GO:0007413)3.72839582
15regulation of cAMP-dependent protein kinase activity (GO:2000479)3.70511029
16negative regulation of microtubule polymerization (GO:0031115)3.62311874
17sequestering of actin monomers (GO:0042989)3.56290446
18lens morphogenesis in camera-type eye (GO:0002089)3.54118464
19cell migration in hindbrain (GO:0021535)3.48236073
20auditory behavior (GO:0031223)3.43943727
21mating behavior (GO:0007617)3.42929686
22positive regulation of action potential (GO:0045760)3.36685244
23neurotransmitter-gated ion channel clustering (GO:0072578)3.32414200
24regulation of action potential (GO:0098900)3.31303870
25protein localization to cilium (GO:0061512)3.31177082
26dendrite morphogenesis (GO:0048813)3.30009253
27positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.27884593
28glutamate receptor signaling pathway (GO:0007215)3.27497271
29vocalization behavior (GO:0071625)3.26510644
30neuronal ion channel clustering (GO:0045161)3.26319523
31regulation of synapse structural plasticity (GO:0051823)3.21272201
32neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976)3.19219397
33synaptic transmission, glutamatergic (GO:0035249)3.18295050
34prepulse inhibition (GO:0060134)3.18066969
35dopaminergic neuron differentiation (GO:0071542)3.14439070
36calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)3.12606809
37axon extension (GO:0048675)3.11858617
38glycosphingolipid biosynthetic process (GO:0006688)3.11208619
39nonmotile primary cilium assembly (GO:0035058)3.09787056
40regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.09643492
41central nervous system projection neuron axonogenesis (GO:0021952)3.07127771
42dopamine biosynthetic process (GO:0042416)3.06680907
43regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.03633854
44urinary tract smooth muscle contraction (GO:0014848)3.01090250
45neurofilament cytoskeleton organization (GO:0060052)2.99367044
46positive regulation of gastrulation (GO:2000543)2.99187713
47neuronal action potential (GO:0019228)2.98336862
48positive regulation of mitochondrial fission (GO:0090141)2.98201550
49negative regulation of synaptic transmission, GABAergic (GO:0032229)2.96068922
50hindbrain development (GO:0030902)2.88576241
51synaptic transmission, cholinergic (GO:0007271)2.88482210
52exploration behavior (GO:0035640)2.87178958
53regulation of synaptic transmission, GABAergic (GO:0032228)2.86678912
54* regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.85441812
55mechanosensory behavior (GO:0007638)2.83930157
56neuron-neuron synaptic transmission (GO:0007270)2.83609967
57suckling behavior (GO:0001967)2.83470269
58positive regulation of synaptic transmission, GABAergic (GO:0032230)2.83001723
59organelle transport along microtubule (GO:0072384)2.82600120
60ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway (GO:0043162.82428661
61positive regulation of synapse assembly (GO:0051965)2.79227642
62establishment of melanosome localization (GO:0032401)2.76305566
63membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.75813818
64dendrite development (GO:0016358)2.75146110
65dopamine receptor signaling pathway (GO:0007212)2.74803093
66cranial nerve morphogenesis (GO:0021602)2.74568284
67neuronal action potential propagation (GO:0019227)2.73657903
68limb bud formation (GO:0060174)2.71640921
69adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)2.70566908
70synapse assembly (GO:0007416)2.70505244
71adult walking behavior (GO:0007628)2.69210288
72ganglion development (GO:0061548)2.67815436
73positive regulation of excitatory postsynaptic membrane potential (GO:2000463)2.67138253
74regulation of feeding behavior (GO:0060259)2.66040357
75regulation of alternative mRNA splicing, via spliceosome (GO:0000381)2.64888568
76forebrain neuron differentiation (GO:0021879)2.64779748
77gamma-aminobutyric acid transport (GO:0015812)2.64663987
78startle response (GO:0001964)2.63905650
79hippocampus development (GO:0021766)2.63495426
80regulation of short-term neuronal synaptic plasticity (GO:0048172)2.63386848
81heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0007157)2.62038942
82positive regulation of microtubule polymerization or depolymerization (GO:0031112)2.61597237
83neuromuscular synaptic transmission (GO:0007274)2.61562504
84axonogenesis (GO:0007409)2.60812991
85innervation (GO:0060384)2.60580786
86sensory perception of smell (GO:0007608)2.60360199
87establishment of pigment granule localization (GO:0051905)2.59952367
88neuron fate specification (GO:0048665)2.59681595
89retinal ganglion cell axon guidance (GO:0031290)2.58162096
90activation of protein kinase A activity (GO:0034199)2.57848590
91negative regulation of axon guidance (GO:1902668)2.57463471
92axon regeneration (GO:0031103)2.57305592
93homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156)2.56931878
94regulation of axon guidance (GO:1902667)2.56632793
95axon extension involved in axon guidance (GO:0048846)2.56103206
96neuron projection extension involved in neuron projection guidance (GO:1902284)2.56103206
97forebrain neuron development (GO:0021884)2.55805347
98substrate-independent telencephalic tangential interneuron migration (GO:0021843)2.55791738
99substrate-independent telencephalic tangential migration (GO:0021826)2.55791738
100response to auditory stimulus (GO:0010996)2.55517475
101membrane hyperpolarization (GO:0060081)2.55083295
102collecting duct development (GO:0072044)2.55008478
103nerve growth factor signaling pathway (GO:0038180)2.54544184
104protein K48-linked ubiquitination (GO:0070936)2.54355961
105cerebral cortex radially oriented cell migration (GO:0021799)2.53685822
106axon cargo transport (GO:0008088)2.53413412
107membrane depolarization during action potential (GO:0086010)2.52499923
108* regulation of respiratory system process (GO:0044065)2.52179126
109postsynaptic membrane organization (GO:0001941)2.51785258
110head development (GO:0060322)2.51237141
111regulation of catecholamine metabolic process (GO:0042069)2.51153319
112regulation of dopamine metabolic process (GO:0042053)2.51153319
113regulation of glutamate receptor signaling pathway (GO:1900449)2.51085183
114neuron projection extension (GO:1990138)2.49714138
115* regulation of respiratory gaseous exchange (GO:0043576)2.49490388
116sympathetic nervous system development (GO:0048485)2.49015485
117regulation of axon extension involved in axon guidance (GO:0048841)2.48777061
118spinal cord motor neuron differentiation (GO:0021522)2.48258021
119nucleobase catabolic process (GO:0046113)2.47731105
120positive regulation of oligodendrocyte differentiation (GO:0048714)2.47615933
121central nervous system neuron axonogenesis (GO:0021955)2.47056866
122synaptic vesicle maturation (GO:0016188)2.45940275
123olfactory bulb development (GO:0021772)2.44919861
124negative regulation of axon extension involved in axon guidance (GO:0048843)2.44555179
125proximal/distal pattern formation (GO:0009954)2.43775067
126catechol-containing compound biosynthetic process (GO:0009713)2.42509394
127catecholamine biosynthetic process (GO:0042423)2.42509394
128retina layer formation (GO:0010842)2.41975632
129negative regulation of cytosolic calcium ion concentration (GO:0051481)2.38790475
130peptidyl-arginine methylation (GO:0018216)2.38092462
131peptidyl-arginine N-methylation (GO:0035246)2.38092462
132positive regulation of RNA splicing (GO:0033120)2.37727450
133body morphogenesis (GO:0010171)2.37525623
134righting reflex (GO:0060013)2.36040269
135neuron migration (GO:0001764)2.34278762
136positive regulation of dendritic spine morphogenesis (GO:0061003)2.33977543
137striatum development (GO:0021756)2.33861225
138regulation of synaptic vesicle exocytosis (GO:2000300)2.33601558
139presynaptic membrane assembly (GO:0097105)2.33575575
140kidney morphogenesis (GO:0060993)2.33313887
141cerebellar Purkinje cell differentiation (GO:0021702)2.32659663
142peptidyl-arginine omega-N-methylation (GO:0035247)2.32507356
143mRNA splice site selection (GO:0006376)2.32332474
144positive regulation of response to oxidative stress (GO:1902884)2.31744325
145positive regulation of cellular response to oxidative stress (GO:1900409)2.31744325
146synaptic vesicle exocytosis (GO:0016079)2.31145608
147regulation of neuron migration (GO:2001222)2.30386132
148regulation of synapse assembly (GO:0051963)2.30286783
149cerebellum development (GO:0021549)2.29839887
150embryonic body morphogenesis (GO:0010172)2.27215283
151transmission of nerve impulse (GO:0019226)2.26627095
152synapse organization (GO:0050808)2.25215497

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.72607914
2GBX2_23144817_ChIP-Seq_PC3_Human3.31370945
3EZH2_27304074_Chip-Seq_ESCs_Mouse2.89481564
4GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.82067610
5JARID2_20064375_ChIP-Seq_MESCs_Mouse2.75521477
6NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.44097437
7* EZH2_18974828_ChIP-Seq_MESCs_Mouse2.43978817
8* RNF2_18974828_ChIP-Seq_MESCs_Mouse2.43978817
9TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.42026470
10* SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.41592254
11CBX2_27304074_Chip-Seq_ESCs_Mouse2.39136437
12TP63_19390658_ChIP-ChIP_HaCaT_Human2.35801458
13EED_16625203_ChIP-ChIP_MESCs_Mouse2.35355125
14* JARID2_20075857_ChIP-Seq_MESCs_Mouse2.34770155
15SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.34515197
16RBPJ_22232070_ChIP-Seq_NCS_Mouse2.34453908
17BMI1_23680149_ChIP-Seq_NPCS_Mouse2.29010511
18SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.24447065
19* SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.23116697
20IGF1R_20145208_ChIP-Seq_DFB_Human2.21273063
21HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.17650798
22CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.10505169
23RNF2_27304074_Chip-Seq_ESCs_Mouse2.10204831
24* SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.08404198
25PHC1_16625203_ChIP-ChIP_MESCs_Mouse2.06991367
26ZNF274_21170338_ChIP-Seq_K562_Hela2.06810127
27EZH2_27294783_Chip-Seq_ESCs_Mouse2.05662426
28RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.94569908
29PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.94218052
30SUZ12_27294783_Chip-Seq_ESCs_Mouse1.90919606
31RNF2_27304074_Chip-Seq_NSC_Mouse1.83194846
32STAT6_21828071_ChIP-Seq_BEAS2B_Human1.82634388
33* MTF2_20144788_ChIP-Seq_MESCs_Mouse1.81256148
34* SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.75332365
35* REST_21632747_ChIP-Seq_MESCs_Mouse1.75220876
36CTBP2_25329375_ChIP-Seq_LNCAP_Human1.72198439
37TAF15_26573619_Chip-Seq_HEK293_Human1.69320910
38POU5F1_16153702_ChIP-ChIP_HESCs_Human1.67299107
39SALL1_21062744_ChIP-ChIP_HESCs_Human1.66349173
40* CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.65415395
41* ZFP57_27257070_Chip-Seq_ESCs_Mouse1.63887819
42* RING1B_27294783_Chip-Seq_NPCs_Mouse1.63014570
43DROSHA_22980978_ChIP-Seq_HELA_Human1.55418822
44CTBP1_25329375_ChIP-Seq_LNCAP_Human1.54336331
45* TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.53121191
46VDR_22108803_ChIP-Seq_LS180_Human1.52915871
47FUS_26573619_Chip-Seq_HEK293_Human1.52322814
48MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.49235912
49HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.48235297
50POU3F2_20337985_ChIP-ChIP_501MEL_Human1.47327247
51P300_19829295_ChIP-Seq_ESCs_Human1.46977367
52* RING1B_27294783_Chip-Seq_ESCs_Mouse1.46750638
53* EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.45214033
54TOP2B_26459242_ChIP-Seq_MCF-7_Human1.41974328
55RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.41866238
56GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.38828119
57* POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.36626404
58* TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.36626404
59PIAS1_25552417_ChIP-Seq_VCAP_Human1.36616978
60* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.36304459
61SMAD3_21741376_ChIP-Seq_EPCs_Human1.35148834
62CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.34388905
63* REST_18959480_ChIP-ChIP_MESCs_Mouse1.33309234
64ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.32028830
65OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.30787979
66SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.30404042
67* CDX2_19796622_ChIP-Seq_MESCs_Mouse1.29288789
68ISL1_27105846_Chip-Seq_CPCs_Mouse1.28111873
69WT1_19549856_ChIP-ChIP_CCG9911_Human1.26992368
70SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.26245491
71SMAD4_21799915_ChIP-Seq_A2780_Human1.25199312
72EWS_26573619_Chip-Seq_HEK293_Human1.25181427
73UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.22123868
74* ER_23166858_ChIP-Seq_MCF-7_Human1.21841040
75RARB_27405468_Chip-Seq_BRAIN_Mouse1.21186241
76* AR_25329375_ChIP-Seq_VCAP_Human1.19713035
77* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.19653053
78STAT3_23295773_ChIP-Seq_U87_Human1.18445732
79MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.17632016
80YAP1_20516196_ChIP-Seq_MESCs_Mouse1.17092694
81FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.15643545
82TAL1_26923725_Chip-Seq_HPCs_Mouse1.15257631
83* SOX2_21211035_ChIP-Seq_LN229_Gbm1.14237257
84GATA1_26923725_Chip-Seq_HPCs_Mouse1.13971165
85ZNF217_24962896_ChIP-Seq_MCF-7_Human1.13582761
86* EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.12244700
87* TP53_20018659_ChIP-ChIP_R1E_Mouse1.11895046
88TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.11860177
89WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.11633328
90NR3C1_23031785_ChIP-Seq_PC12_Mouse1.11624312
91IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.11466613
92CBP_20019798_ChIP-Seq_JUKART_Human1.11466613
93* RUNX2_22187159_ChIP-Seq_PCA_Human1.10153968
94AHR_22903824_ChIP-Seq_MCF-7_Human1.10095145
95ARNT_22903824_ChIP-Seq_MCF-7_Human1.08951312
96TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.08670924
97AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.08347527
98SOX9_26525672_Chip-Seq_HEART_Mouse1.07812540
99DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.06447584
100NR3C1_21868756_ChIP-Seq_MCF10A_Human1.06054120
101SOX2_16153702_ChIP-ChIP_HESCs_Human1.05509205
102* TCF4_23295773_ChIP-Seq_U87_Human1.04845266
103* TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.04781484
104ERG_21242973_ChIP-ChIP_JURKAT_Human1.04769376
105AR_21572438_ChIP-Seq_LNCaP_Human1.03352395
106* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.02325927
107FLI1_27457419_Chip-Seq_LIVER_Mouse1.00199184
108AR_19668381_ChIP-Seq_PC3_Human1.00029235
109KDM2B_26808549_Chip-Seq_REH_Human1.00008462
110ZFP281_18757296_ChIP-ChIP_E14_Mouse0.99527744
111LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.99507195
112* STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse0.99304871
113* NANOG_18555785_Chip-Seq_ESCs_Mouse0.99012168
114KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse0.98843785
115CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.98617736
116PCGF2_27294783_Chip-Seq_ESCs_Mouse0.97977648
117IRF1_19129219_ChIP-ChIP_H3396_Human0.97915525
118TP53_18474530_ChIP-ChIP_U2OS_Human0.97034605
119SALL4_18804426_ChIP-ChIP_MESCs_Mouse0.95832570
120JUN_21703547_ChIP-Seq_K562_Human0.94641621
121TRIM28_17542650_ChIP-ChIP_NTERA2_Human0.93479757
122EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.93064875

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern3.15684933
2MP0003122_maternal_imprinting2.77875912
3MP0000569_abnormal_digit_pigmentation2.58809809
4MP0000778_abnormal_nervous_system2.58190304
5MP0001188_hyperpigmentation2.55692940
6MP0002735_abnormal_chemical_nociception2.34613526
7MP0006276_abnormal_autonomic_nervous2.31389685
8MP0002184_abnormal_innervation2.19851006
9MP0000537_abnormal_urethra_morphology2.18727929
10MP0001529_abnormal_vocalization2.10661721
11MP0003890_abnormal_embryonic-extraembry2.09097810
12MP0003635_abnormal_synaptic_transmissio2.01647626
13MP0005645_abnormal_hypothalamus_physiol1.95006970
14MP0008789_abnormal_olfactory_epithelium1.89558288
15MP0002822_catalepsy1.87440573
16MP0003121_genomic_imprinting1.86133195
17MP0006072_abnormal_retinal_apoptosis1.83863851
18MP0010030_abnormal_orbit_morphology1.83594380
19MP0010386_abnormal_urinary_bladder1.82525685
20MP0002063_abnormal_learning/memory/cond1.81315357
21MP0000631_abnormal_neuroendocrine_gland1.78038130
22MP0003283_abnormal_digestive_organ1.75357568
23MP0004859_abnormal_synaptic_plasticity1.71666487
24MP0002909_abnormal_adrenal_gland1.71643345
25MP0001486_abnormal_startle_reflex1.69664290
26MP0005499_abnormal_olfactory_system1.67731407
27MP0005394_taste/olfaction_phenotype1.67731407
28MP0003119_abnormal_digestive_system1.66720214
29MP0002102_abnormal_ear_morphology1.66634432
30MP0004270_analgesia1.63465471
31MP0001984_abnormal_olfaction1.61555425
32MP0003385_abnormal_body_wall1.60318307
33MP0003942_abnormal_urinary_system1.57417903
34MP0002557_abnormal_social/conspecific_i1.57137407
35MP0005248_abnormal_Harderian_gland1.56300126
36MP0005187_abnormal_penis_morphology1.55078246
37MP0000049_abnormal_middle_ear1.52120216
38MP0002734_abnormal_mechanical_nocicepti1.51470902
39MP0003787_abnormal_imprinting1.49425998
40* MP0005423_abnormal_somatic_nervous1.47251164
41MP0002751_abnormal_autonomic_nervous1.46040150
42MP0002572_abnormal_emotion/affect_behav1.45090695
43MP0008877_abnormal_DNA_methylation1.43751934
44MP0001905_abnormal_dopamine_level1.41597657
45MP0004811_abnormal_neuron_physiology1.39582401
46MP0002736_abnormal_nociception_after1.39500691
47MP0005409_darkened_coat_color1.35969873
48MP0003937_abnormal_limbs/digits/tail_de1.34716728
49MP0002837_dystrophic_cardiac_calcinosis1.34480104
50MP0003861_abnormal_nervous_system1.33496645
51MP0001440_abnormal_grooming_behavior1.33380126
52MP0002882_abnormal_neuron_morphology1.32040698
53MP0003123_paternal_imprinting1.31304026
54MP0000955_abnormal_spinal_cord1.28372054
55MP0009053_abnormal_anal_canal1.26375333
56MP0002152_abnormal_brain_morphology1.26009388
57MP0009745_abnormal_behavioral_response1.23575173
58MP0001485_abnormal_pinna_reflex1.23184698
59MP0002233_abnormal_nose_morphology1.23035681
60MP0003315_abnormal_perineum_morphology1.21800339
61MP0001299_abnormal_eye_distance/1.20913302
62MP0004742_abnormal_vestibular_system1.20478555
63MP0004924_abnormal_behavior1.19368581
64MP0005386_behavior/neurological_phenoty1.19368581
65MP0000566_synostosis1.17595370
66MP0002752_abnormal_somatic_nervous1.16311657
67MP0000538_abnormal_urinary_bladder1.13983973
68MP0003755_abnormal_palate_morphology1.13879267
69MP0009250_abnormal_appendicular_skeleto1.12590135
70MP0000534_abnormal_ureter_morphology1.12167341
71MP0002234_abnormal_pharynx_morphology1.09868191
72MP0002272_abnormal_nervous_system1.09720091
73MP0009379_abnormal_foot_pigmentation1.09155897
74MP0002733_abnormal_thermal_nociception1.08588515
75MP0002928_abnormal_bile_duct1.07895119
76MP0002638_abnormal_pupillary_reflex1.07858622
77MP0002067_abnormal_sensory_capabilities1.07214273
78MP0002064_seizures1.06616577
79MP0002066_abnormal_motor_capabilities/c1.05013367
80MP0002697_abnormal_eye_size1.04935165
81MP0002177_abnormal_outer_ear1.04687960
82MP0005367_renal/urinary_system_phenotyp1.03834861
83MP0000516_abnormal_urinary_system1.03834861
84MP0001286_abnormal_eye_development1.02917913
85MP0004133_heterotaxia1.00005542
86MP0005551_abnormal_eye_electrophysiolog0.98719859
87MP0002653_abnormal_ependyma_morphology0.98446830
88MP0003935_abnormal_craniofacial_develop0.98440038
89MP0005084_abnormal_gallbladder_morpholo0.98367258
90MP0005646_abnormal_pituitary_gland0.97969544
91MP0005253_abnormal_eye_physiology0.97652944
92MP0002116_abnormal_craniofacial_bone0.96878949
93MP0001346_abnormal_lacrimal_gland0.96386433
94MP0003879_abnormal_hair_cell0.96053869
95* MP0002081_perinatal_lethality0.94749556
96MP0000026_abnormal_inner_ear0.93694844
97MP0000647_abnormal_sebaceous_gland0.93026525
98MP0003938_abnormal_ear_development0.92518775
99MP0002938_white_spotting0.91158930
100MP0009046_muscle_twitch0.90506437
101MP0001970_abnormal_pain_threshold0.90312517
102MP0001502_abnormal_circadian_rhythm0.89729591
103MP0002069_abnormal_eating/drinking_beha0.87395701
104MP0001177_atelectasis0.87257912
105MP0004085_abnormal_heartbeat0.86390187
106MP0004885_abnormal_endolymph0.85713271
107MP0005195_abnormal_posterior_eye0.85026348
108MP0001968_abnormal_touch/_nociception0.84658052
109MP0006292_abnormal_olfactory_placode0.84164770
110MP0009780_abnormal_chondrocyte_physiolo0.83697389
111MP0001293_anophthalmia0.83370397
112MP0004142_abnormal_muscle_tone0.82087996
113MP0003567_abnormal_fetal_cardiomyocyte0.80329453
114MP0004145_abnormal_muscle_electrophysio0.77168913
115MP0002163_abnormal_gland_morphology0.73375028
116MP0003221_abnormal_cardiomyocyte_apopto0.70451373
117MP0001963_abnormal_hearing_physiology0.68812928
118MP0008569_lethality_at_weaning0.67642980
119MP0003137_abnormal_impulse_conducting0.65884956
120MP0008995_early_reproductive_senescence0.64513351
121MP0002082_postnatal_lethality0.64166639
122MP0010770_preweaning_lethality0.64166639
123MP0003633_abnormal_nervous_system0.62530541

Predicted human phenotypes

RankGene SetZ-score
1Limb dystonia (HP:0002451)4.99477425
2Polyphagia (HP:0002591)4.55481581
3Abnormality of the corticospinal tract (HP:0002492)3.69238272
4Atonic seizures (HP:0010819)3.56481032
5Focal seizures (HP:0007359)3.44937220
6Degeneration of the lateral corticospinal tracts (HP:0002314)3.38482261
7Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)3.38482261
8Febrile seizures (HP:0002373)3.27291876
9Lissencephaly (HP:0001339)3.07977607
10Cortical dysplasia (HP:0002539)2.96587763
11Morphological abnormality of the middle ear (HP:0008609)2.89321224
12Dialeptic seizures (HP:0011146)2.84674049
13Abnormality of the labia minora (HP:0012880)2.84360756
14Nephrogenic diabetes insipidus (HP:0009806)2.80901862
15Pachygyria (HP:0001302)2.78284203
16Urinary urgency (HP:0000012)2.76935280
17Abnormality of the right ventricle (HP:0001707)2.76479619
18Bifid tongue (HP:0010297)2.75119176
19Focal motor seizures (HP:0011153)2.72463137
20Abnormal hair whorl (HP:0010721)2.71175882
21Absence seizures (HP:0002121)2.64933438
22Agitation (HP:0000713)2.64434704
23Volvulus (HP:0002580)2.62896140
24Progressive cerebellar ataxia (HP:0002073)2.62483672
25Hyperventilation (HP:0002883)2.57734274
26Aplasia/Hypoplasia of the brainstem (HP:0007362)2.56396843
27Hypoplasia of the brainstem (HP:0002365)2.56396843
28Esotropia (HP:0000565)2.47414578
29Hypoplastic labia majora (HP:0000059)2.46791102
30Cutaneous finger syndactyly (HP:0010554)2.45192609
31Abnormal eating behavior (HP:0100738)2.44821859
32EEG with generalized epileptiform discharges (HP:0011198)2.43434407
33Hypsarrhythmia (HP:0002521)2.43258093
34Morphological abnormality of the pyramidal tract (HP:0002062)2.40821578
35Epileptiform EEG discharges (HP:0011182)2.39366001
36Impaired vibration sensation in the lower limbs (HP:0002166)2.38857372
37Renal duplication (HP:0000075)2.38478530
38Nephronophthisis (HP:0000090)2.35297637
39Pancreatic fibrosis (HP:0100732)2.34723207
40Generalized tonic-clonic seizures (HP:0002069)2.33081226
41Spastic tetraplegia (HP:0002510)2.28946216
42Abnormality of the labia majora (HP:0012881)2.26981599
43Midline defect of the nose (HP:0004122)2.23624090
44Pancreatic cysts (HP:0001737)2.23166429
45Decreased circulating renin level (HP:0003351)2.22414613
46Symphalangism affecting the phalanges of the hand (HP:0009773)2.22259179
47Broad-based gait (HP:0002136)2.20731960
48Broad alveolar ridges (HP:0000187)2.20303367
49Abnormality of the lower motor neuron (HP:0002366)2.19996293
50Labial hypoplasia (HP:0000066)2.16950336
51Urinary bladder sphincter dysfunction (HP:0002839)2.16282826
52Epileptic encephalopathy (HP:0200134)2.14635155
53Ulnar claw (HP:0001178)2.14532896
54Exotropia (HP:0000577)2.11845707
55True hermaphroditism (HP:0010459)2.10687447
56Insidious onset (HP:0003587)2.07705008
57Termporal pattern (HP:0011008)2.07705008
58Excessive salivation (HP:0003781)2.06357922
59Drooling (HP:0002307)2.06357922
60Narrow nasal bridge (HP:0000446)2.06252884
61Short 4th metacarpal (HP:0010044)2.06022922
62Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.06022922
63Cutaneous syndactyly (HP:0012725)2.04748734
64Poor coordination (HP:0002370)2.04128470
65Increased number of teeth (HP:0011069)2.03171764
66Asymmetry of the thorax (HP:0001555)2.01899274
67Sacral dimple (HP:0000960)2.01050224
68Hip dysplasia (HP:0001385)2.00710040
69Broad nasal tip (HP:0000455)2.00351089
70Bronchomalacia (HP:0002780)1.98513113
71Specific learning disability (HP:0001328)1.98231358
72Tented upper lip vermilion (HP:0010804)1.97968918
73Absent eyebrow (HP:0002223)1.97611489
74Facial hemangioma (HP:0000329)1.97588029
75Macroorchidism (HP:0000053)1.96786789
76Intellectual disability, moderate (HP:0002342)1.96298810
77Retinal dysplasia (HP:0007973)1.95449803
78Optic nerve hypoplasia (HP:0000609)1.94794872
79Atrophy/Degeneration involving motor neurons (HP:0007373)1.94683923
80Poor suck (HP:0002033)1.94180237
81Broad foot (HP:0001769)1.92479794
82Protruding tongue (HP:0010808)1.92219713
83Amyotrophic lateral sclerosis (HP:0007354)1.91528058
84Gait imbalance (HP:0002141)1.90484098
85Papillary thyroid carcinoma (HP:0002895)1.89753474
86Paraplegia (HP:0010550)1.88132823
87Gastroesophageal reflux (HP:0002020)1.88003908
88Methylmalonic acidemia (HP:0002912)1.86840996
89Ankle clonus (HP:0011448)1.86631291
90Renal hypoplasia (HP:0000089)1.85944292
91Mutism (HP:0002300)1.84790716
92Hypoplastic female external genitalia (HP:0012815)1.84378788
93Central scotoma (HP:0000603)1.83320595
94Abnormality of the middle phalanx of the 5th finger (HP:0004219)1.83077768
95Pheochromocytoma (HP:0002666)1.82796219
96Inappropriate behavior (HP:0000719)1.82642624
97Genetic anticipation (HP:0003743)1.82496183
98Anencephaly (HP:0002323)1.82384744
99Septo-optic dysplasia (HP:0100842)1.81147513
100Failure to thrive in infancy (HP:0001531)1.80586237
101Chronic hepatic failure (HP:0100626)1.80538065
102Short philtrum (HP:0000322)1.80188135
103Abnormal number of incisors (HP:0011064)1.79926579
104Abnormality of the phalanges of the 5th finger (HP:0004213)1.79411403
105Shoulder girdle muscle weakness (HP:0003547)1.79212578
106Hypothermia (HP:0002045)1.79004441
107Postaxial hand polydactyly (HP:0001162)1.78029859
108Ankyloglossia (HP:0010296)1.77894604
109Myokymia (HP:0002411)1.77870549
110Abnormality of the renal medulla (HP:0100957)1.77608929
111Amblyopia (HP:0000646)1.77305530
112Spastic gait (HP:0002064)1.77103399
113Megalencephaly (HP:0001355)1.76743448
114Abnormal pancreas size (HP:0012094)1.76176558
115Oligodactyly (hands) (HP:0001180)1.76122754
116Elevated circulating parathyroid hormone (PTH) level (HP:0003165)1.75533879
117Myelomeningocele (HP:0002475)1.75513918
118Generalized myoclonic seizures (HP:0002123)1.75081051
119Tracheomalacia (HP:0002779)1.75030275
120Thin upper lip vermilion (HP:0000219)1.74940403
121Fetal akinesia sequence (HP:0001989)1.73652027
122Heterochromia iridis (HP:0001100)1.73589767
123Abnormality of the parathyroid morphology (HP:0011766)1.73365992
124Vaginal atresia (HP:0000148)1.73359526
125Hepatoblastoma (HP:0002884)1.72329598
126Narrow forehead (HP:0000341)1.72098442
127Genital tract atresia (HP:0001827)1.69313341
128Bicornuate uterus (HP:0000813)1.66937260
129Abnormality of the nasal septum (HP:0000419)1.65554144
130Intestinal atresia (HP:0011100)1.64953791
131Hypoventilation (HP:0002791)1.64808706
132Anophthalmia (HP:0000528)1.64690071
133Heterotopia (HP:0002282)1.64397568
134Sleep apnea (HP:0010535)1.60697484
135Medial flaring of the eyebrow (HP:0010747)1.59963344
136Abnormality of macular pigmentation (HP:0008002)1.59496602
137Buphthalmos (HP:0000557)1.58877830
138Patellar aplasia (HP:0006443)1.57066856
139Abnormality of the diencephalon (HP:0010662)1.55753862
140Visual hallucinations (HP:0002367)1.55292866
141Supernumerary spleens (HP:0009799)1.54251648
142Bony spicule pigmentary retinopathy (HP:0007737)1.53472708
143Atrioventricular canal defect (HP:0006695)1.53416830
144Micropenis (HP:0000054)1.53401252
145Abnormality of midbrain morphology (HP:0002418)1.53389865
146Molar tooth sign on MRI (HP:0002419)1.53389865
147Truncal ataxia (HP:0002078)1.53351957
148Aplasia/Hypoplasia of the lens (HP:0008063)1.52838965
149Abnormality of salivation (HP:0100755)1.52279355
150Scotoma (HP:0000575)1.52074526
151Congenital primary aphakia (HP:0007707)1.51265868
152Growth hormone deficiency (HP:0000824)1.51226179
153Hypoplasia of the maxilla (HP:0000327)1.51196642
154Absent speech (HP:0001344)1.50749442
155Aplasia/Hypoplasia of the patella (HP:0006498)1.50107311
156Increased nuchal translucency (HP:0010880)1.49847560
157Hydroureter (HP:0000072)1.49604397
158Shawl scrotum (HP:0000049)1.49528357
159Hamartoma (HP:0010566)1.49450364
160Pointed chin (HP:0000307)1.48691884
161Nasal speech (HP:0001611)1.48515839
162High anterior hairline (HP:0009890)1.48407512
163Increased corneal curvature (HP:0100692)1.48310573

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MARK15.42296080
2BMPR1B3.38731783
3MAPK132.96532482
4ERBB32.92498872
5UHMK12.41370297
6DYRK22.39028635
7NTRK22.36340593
8CASK2.10588556
9MKNK11.93551856
10MINK11.93136665
11MAP3K41.88038357
12MAP2K71.80961603
13CSNK1G31.76570199
14EPHB21.74276488
15NTRK31.71167140
16BCR1.71073022
17CSNK1G21.70349060
18PINK11.65538460
19SIK21.60481049
20TRIM281.58834784
21PLK21.53524256
22CDK191.51549780
23CSNK1A1L1.46091810
24EPHA41.45598047
25LATS21.42250421
26MKNK21.42143213
27SRPK11.36220751
28PNCK1.36011507
29CSNK1G11.35514869
30KSR11.34452239
31PRKD31.28232062
32MAP3K91.21252395
33PHKG11.17693389
34PHKG21.17693389
35PASK1.17349402
36CAMK1G1.14321312
37INSRR1.13579439
38ICK1.12915904
39RPS6KA21.08869343
40SIK31.01570245
41DYRK31.00999398
42HIPK21.00090147
43BRD40.98189134
44TAOK10.97520455
45MAP4K20.96020276
46PAK60.94733148
47PAK30.93505010
48CDK50.93333772
49SGK4940.90084863
50SGK2230.90084863
51STK160.89961773
52DYRK1A0.89124013
53LIMK10.85285872
54CDC42BPA0.81752518
55PKN10.81057685
56FGFR10.79428451
57MAP3K50.75745491
58DYRK1B0.74107414
59ADRBK20.73652960
60CDK140.72552346
61ALK0.72281147
62CDK180.72112479
63LATS10.69839652
64ROCK10.68816987
65SGK20.68689758
66PTK60.66880247
67ERBB20.64523225
68CDK150.62944215
69GRK70.61712230
70MAP2K40.61694022
71WNK30.60810964
72DAPK20.60666015
73AKT30.60546690
74PRKCE0.59876571
75RET0.59752004
76PLK30.59680525
77FGFR20.58922672
78ADRBK10.58310455
79CAMKK10.58232298
80MAPK90.57779172
81MARK20.56789327
82YES10.56666604
83STK110.56492356
84FRK0.56196816
85CDK11A0.54692694
86WNK10.53755175
87EPHA30.53616963
88CAMK40.52311081
89PRKCZ0.52122808
90FGFR30.52067789
91GRK10.51728495
92CAMK2B0.51590846
93PRKCG0.50830515
94CAMK2A0.49746801
95MAPKAPK50.49524836
96MAP3K20.49459081
97TYRO30.48571456
98BRAF0.48531769
99CSNK1E0.47897290
100IRAK20.45025214
101PRKD20.44986467
102PRKG10.44623896
103RPS6KL10.43647166
104RPS6KC10.43647166
105MAP3K60.43553584
106GSK3B0.43532941
107RIPK10.43531164
108PRKACB0.42727090
109CSNK1D0.42623439
110TNIK0.42410975
111AKT10.42204895
112CAMK1D0.41708036
113PRKACA0.40332106
114NTRK10.39916950
115CAMK2D0.37083562
116PRKAA10.36190091
117MAPK150.34041346
118CAMK10.30745552
119MAP3K120.28756711
120CAMKK20.28539877
121OBSCN0.28299198
122FLT30.28041632
123CSNK1A10.27826721
124PRKACG0.26552374
125TESK10.25490213
126SGK10.22990055
127RPS6KA30.22729224
128RPS6KA40.22682362
129TAOK30.21776859
130EGFR0.21707750

Predicted pathways (KEGG)

RankGene SetZ-score
1Phototransduction_Homo sapiens_hsa047442.62712508
2Cocaine addiction_Homo sapiens_hsa050302.43152253
3Olfactory transduction_Homo sapiens_hsa047402.28037943
4Dopaminergic synapse_Homo sapiens_hsa047282.23202542
5Steroid biosynthesis_Homo sapiens_hsa001002.03146603
6GABAergic synapse_Homo sapiens_hsa047272.00738968
7Cholinergic synapse_Homo sapiens_hsa047252.00735491
8Nicotine addiction_Homo sapiens_hsa050331.99442347
9Insulin secretion_Homo sapiens_hsa049111.95812559
10Axon guidance_Homo sapiens_hsa043601.93970256
11Amphetamine addiction_Homo sapiens_hsa050311.89887069
12Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.89720676
13Circadian entrainment_Homo sapiens_hsa047131.83468303
14Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.77343138
15Serotonergic synapse_Homo sapiens_hsa047261.76410739
16Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.76229339
17Morphine addiction_Homo sapiens_hsa050321.72515006
18Aldosterone synthesis and secretion_Homo sapiens_hsa049251.70948722
19Synaptic vesicle cycle_Homo sapiens_hsa047211.68538348
20Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.66136420
21Maturity onset diabetes of the young_Homo sapiens_hsa049501.62886992
22Collecting duct acid secretion_Homo sapiens_hsa049661.60425413
23Glutamatergic synapse_Homo sapiens_hsa047241.59368108
24Gap junction_Homo sapiens_hsa045401.47681193
25Oxidative phosphorylation_Homo sapiens_hsa001901.47531340
26Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.43957012
27Alcoholism_Homo sapiens_hsa050341.43816375
28Melanogenesis_Homo sapiens_hsa049161.42963043
29Taste transduction_Homo sapiens_hsa047421.42294443
30Hedgehog signaling pathway_Homo sapiens_hsa043401.41967216
31mRNA surveillance pathway_Homo sapiens_hsa030151.40129160
32Endometrial cancer_Homo sapiens_hsa052131.39681940
33Long-term potentiation_Homo sapiens_hsa047201.39234746
34Basal cell carcinoma_Homo sapiens_hsa052171.38396680
35Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.25197189
36Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.24627932
37Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.21708730
38Wnt signaling pathway_Homo sapiens_hsa043101.21472434
39Type II diabetes mellitus_Homo sapiens_hsa049301.16074519
40Colorectal cancer_Homo sapiens_hsa052101.14238597
41Oocyte meiosis_Homo sapiens_hsa041141.14048623
42Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.14041865
43Hippo signaling pathway_Homo sapiens_hsa043901.13553689
44Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.12666909
45Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.12158376
46Renin secretion_Homo sapiens_hsa049241.11591469
47GnRH signaling pathway_Homo sapiens_hsa049121.09971391
48Butanoate metabolism_Homo sapiens_hsa006501.06717646
49Long-term depression_Homo sapiens_hsa047301.05437151
50Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.05367119
51Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.04965416
52ErbB signaling pathway_Homo sapiens_hsa040121.04886777
53Renal cell carcinoma_Homo sapiens_hsa052111.04767268
54Estrogen signaling pathway_Homo sapiens_hsa049151.04436209
55Oxytocin signaling pathway_Homo sapiens_hsa049211.04049598
56Dilated cardiomyopathy_Homo sapiens_hsa054141.03822952
57Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.03135028
58Cardiac muscle contraction_Homo sapiens_hsa042600.95915053
59Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.94568399
60Vibrio cholerae infection_Homo sapiens_hsa051100.92469507
61Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.92132247
62Glioma_Homo sapiens_hsa052140.90664158
63Thyroid hormone signaling pathway_Homo sapiens_hsa049190.89960143
64Gastric acid secretion_Homo sapiens_hsa049710.89467069
65Rap1 signaling pathway_Homo sapiens_hsa040150.87302456
66Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.86152986
67Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.85262395
68Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.84795866
69Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.84641690
70Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.83377461
71cGMP-PKG signaling pathway_Homo sapiens_hsa040220.83344729
72Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.82847749
73cAMP signaling pathway_Homo sapiens_hsa040240.81962254
74Ovarian steroidogenesis_Homo sapiens_hsa049130.79892037
75Non-small cell lung cancer_Homo sapiens_hsa052230.79741943
76Tight junction_Homo sapiens_hsa045300.78965260
77Parkinsons disease_Homo sapiens_hsa050120.78769436
78MAPK signaling pathway_Homo sapiens_hsa040100.77803442
79mTOR signaling pathway_Homo sapiens_hsa041500.77720101
80Circadian rhythm_Homo sapiens_hsa047100.77716511
81Longevity regulating pathway - mammal_Homo sapiens_hsa042110.77381732
82Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.75649093
83Basal transcription factors_Homo sapiens_hsa030220.75604716
84Ras signaling pathway_Homo sapiens_hsa040140.74066345
85MicroRNAs in cancer_Homo sapiens_hsa052060.73521652
86Calcium signaling pathway_Homo sapiens_hsa040200.72868710
87Neurotrophin signaling pathway_Homo sapiens_hsa047220.72794795
88Salivary secretion_Homo sapiens_hsa049700.72728931
89Prostate cancer_Homo sapiens_hsa052150.69828273
90Melanoma_Homo sapiens_hsa052180.69385814
91Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.69132373
92Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.68262871
93Regulation of autophagy_Homo sapiens_hsa041400.67467124
94Notch signaling pathway_Homo sapiens_hsa043300.65262972
95Prolactin signaling pathway_Homo sapiens_hsa049170.64784375
96Protein export_Homo sapiens_hsa030600.64466905
97Vascular smooth muscle contraction_Homo sapiens_hsa042700.64040558
98Insulin signaling pathway_Homo sapiens_hsa049100.61371327
99Glucagon signaling pathway_Homo sapiens_hsa049220.60943334
100Adherens junction_Homo sapiens_hsa045200.60396529
101Pathways in cancer_Homo sapiens_hsa052000.58633489
102Chronic myeloid leukemia_Homo sapiens_hsa052200.57785591
103Pancreatic secretion_Homo sapiens_hsa049720.57709948
104Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.54699503
105Thyroid hormone synthesis_Homo sapiens_hsa049180.54015661
106Alzheimers disease_Homo sapiens_hsa050100.51956574
107AMPK signaling pathway_Homo sapiens_hsa041520.50681455
108Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.50602485
109Huntingtons disease_Homo sapiens_hsa050160.50356230
110Carbohydrate digestion and absorption_Homo sapiens_hsa049730.49993430
111Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.49947306
112Prion diseases_Homo sapiens_hsa050200.48947998
113Lysine degradation_Homo sapiens_hsa003100.48944646
114Spliceosome_Homo sapiens_hsa030400.48078070
115Dorso-ventral axis formation_Homo sapiens_hsa043200.46853015
116Thyroid cancer_Homo sapiens_hsa052160.45429270
117Cell cycle_Homo sapiens_hsa041100.45236735
118Ether lipid metabolism_Homo sapiens_hsa005650.45076242
119Phospholipase D signaling pathway_Homo sapiens_hsa040720.44886731
120Phagosome_Homo sapiens_hsa041450.39761270
121Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.39627744
122Peroxisome_Homo sapiens_hsa041460.38893428
123Salmonella infection_Homo sapiens_hsa051320.30288199
124Propanoate metabolism_Homo sapiens_hsa006400.29750627
125Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.27563107

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