PCDH20

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. This gene encodes a protein which contains 6 extracellular cadherin domains, a transmembrane domain and a cytoplasmic tail differing from those of the classical cadherins. Although its specific function is undetermined, the cadherin-related neuronal receptor is thought to play a role in the establishment and function of specific cell-cell connections in the brain. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of short-term neuronal synaptic plasticity (GO:0048172)6.18199928
2vocalization behavior (GO:0071625)5.74345851
3regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act5.66615703
4ionotropic glutamate receptor signaling pathway (GO:0035235)5.58633114
5positive regulation of excitatory postsynaptic membrane potential (GO:2000463)5.55816666
6neuron cell-cell adhesion (GO:0007158)5.55311795
7regulation of glutamate receptor signaling pathway (GO:1900449)5.28630967
8locomotory exploration behavior (GO:0035641)5.20607374
9protein localization to synapse (GO:0035418)5.14967261
10glutamate receptor signaling pathway (GO:0007215)5.05593078
11synaptic vesicle exocytosis (GO:0016079)5.01268930
12regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)4.96975811
13neurotransmitter-gated ion channel clustering (GO:0072578)4.84646778
14positive regulation of synapse maturation (GO:0090129)4.84150965
15pyrimidine nucleobase catabolic process (GO:0006208)4.72145485
16exploration behavior (GO:0035640)4.70193158
17synaptic vesicle maturation (GO:0016188)4.67584684
18glutamate secretion (GO:0014047)4.63608485
19synaptic transmission, glutamatergic (GO:0035249)4.55222275
20regulation of neuronal synaptic plasticity (GO:0048168)4.54452355
21regulation of long-term neuronal synaptic plasticity (GO:0048169)4.44139985
22neuronal action potential propagation (GO:0019227)4.44054615
23neuron-neuron synaptic transmission (GO:0007270)4.37689253
24positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.32229596
25nucleobase catabolic process (GO:0046113)4.31054091
26gamma-aminobutyric acid signaling pathway (GO:0007214)4.26753806
27regulation of excitatory postsynaptic membrane potential (GO:0060079)4.26567422
28long-term memory (GO:0007616)4.22420812
29neuron recognition (GO:0008038)4.21595116
30response to histamine (GO:0034776)4.18080996
31synaptic vesicle docking involved in exocytosis (GO:0016081)4.16920322
32long-term synaptic potentiation (GO:0060291)4.15564422
33behavioral defense response (GO:0002209)4.12649860
34behavioral fear response (GO:0001662)4.12649860
35presynaptic membrane assembly (GO:0097105)4.12104486
36postsynaptic membrane organization (GO:0001941)4.10407478
37regulation of synaptic vesicle exocytosis (GO:2000300)4.06619562
38regulation of postsynaptic membrane potential (GO:0060078)4.00332479
39cellular potassium ion homeostasis (GO:0030007)3.98823997
40regulation of synaptic plasticity (GO:0048167)3.96166974
41axonal fasciculation (GO:0007413)3.93055991
42negative regulation of synaptic transmission, GABAergic (GO:0032229)3.91062491
43negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.79842859
44regulation of synapse maturation (GO:0090128)3.79648451
45fear response (GO:0042596)3.79228412
46neurotransmitter secretion (GO:0007269)3.78645753
47regulation of synaptic transmission, glutamatergic (GO:0051966)3.78621269
48regulation of synaptic vesicle transport (GO:1902803)3.78266213
49proline transport (GO:0015824)3.76416131
50startle response (GO:0001964)3.75725160
51presynaptic membrane organization (GO:0097090)3.70347200
52positive regulation of membrane potential (GO:0045838)3.65213409
53G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.63227541
54regulation of synapse structural plasticity (GO:0051823)3.59366180
55regulation of dendritic spine morphogenesis (GO:0061001)3.54843359
56membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.50610044
57G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)3.48863553
58transmission of nerve impulse (GO:0019226)3.48072638
59positive regulation of dendritic spine morphogenesis (GO:0061003)3.46323669
60gamma-aminobutyric acid transport (GO:0015812)3.45549860
61innervation (GO:0060384)3.38130446
62positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.35044851
63synaptic vesicle endocytosis (GO:0048488)3.34708926
64dendritic spine morphogenesis (GO:0060997)3.33868929
65sodium ion export (GO:0071436)3.32805983
66neuronal ion channel clustering (GO:0045161)3.32447102
67positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.29394149
68regulation of female receptivity (GO:0045924)3.28091202
69cerebellar granule cell differentiation (GO:0021707)3.26718544
70cell communication by electrical coupling (GO:0010644)3.25330721
71cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.25073886
72learning (GO:0007612)3.23507563
73regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.23259595
74positive regulation of dendritic spine development (GO:0060999)3.22863367
75regulation of inositol phosphate biosynthetic process (GO:0010919)3.20962045
76membrane depolarization (GO:0051899)3.20834709
77regulation of synaptic transmission (GO:0050804)3.19449236
78cerebellar Purkinje cell differentiation (GO:0021702)3.18359450
79cochlea development (GO:0090102)3.17857856
80layer formation in cerebral cortex (GO:0021819)3.17608482
81neurotransmitter transport (GO:0006836)3.15527655
82regulation of vesicle fusion (GO:0031338)3.15386819
83regulation of dendritic spine development (GO:0060998)3.14838316
84protein localization to cilium (GO:0061512)3.11943827
85detection of calcium ion (GO:0005513)3.10369634
86positive regulation of synaptic transmission (GO:0050806)3.08414009
87female mating behavior (GO:0060180)3.05955792
88central nervous system projection neuron axonogenesis (GO:0021952)3.03289718
89synaptic transmission (GO:0007268)3.02766946
90regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.02568246
91positive regulation of synaptic transmission, GABAergic (GO:0032230)3.02338500
92cellular sodium ion homeostasis (GO:0006883)3.02121688
93positive regulation of synapse assembly (GO:0051965)3.01581450
94serotonin receptor signaling pathway (GO:0007210)3.01326726
95long term synaptic depression (GO:0060292)2.99878552
96regulation of neurotransmitter secretion (GO:0046928)2.99591853
97dendritic spine organization (GO:0097061)2.99522563
98positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.99361056
99cell communication involved in cardiac conduction (GO:0086065)2.98641497
100glycosphingolipid biosynthetic process (GO:0006688)2.97905785
101regulation of voltage-gated calcium channel activity (GO:1901385)2.97081509
102vesicle transport along microtubule (GO:0047496)2.96687696
103membrane hyperpolarization (GO:0060081)2.94947321
104negative regulation of amyloid precursor protein catabolic process (GO:1902992)2.93944940
105regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.92184832
106neuromuscular process controlling posture (GO:0050884)2.91858067
107positive regulation of neurotransmitter secretion (GO:0001956)2.91593890
108regulation of neurotransmitter levels (GO:0001505)2.89621775
109dendrite morphogenesis (GO:0048813)2.88682950
110negative regulation of dendrite development (GO:2000171)2.85078493
111establishment of mitochondrion localization (GO:0051654)2.77026500
112atrial cardiac muscle cell action potential (GO:0086014)2.75078251
113apical protein localization (GO:0045176)2.71649497
114negative regulation of cytosolic calcium ion concentration (GO:0051481)2.69099418
115negative regulation of hormone biosynthetic process (GO:0032353)2.65475421
116positive regulation of neurotransmitter transport (GO:0051590)2.62229942
117cell migration in hindbrain (GO:0021535)2.60655119
118retinal cone cell development (GO:0046549)2.59015906
119cardiac conduction (GO:0061337)2.56404721
120gonadal mesoderm development (GO:0007506)2.55096423
121regulation of heart rate by cardiac conduction (GO:0086091)2.51241948
122regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)2.47490815
123negative regulation of heart rate (GO:0010459)2.45302864
124membrane depolarization during action potential (GO:0086010)2.44972039
125mitochondrion distribution (GO:0048311)2.43647880
126regulation of cell communication by electrical coupling (GO:0010649)2.43542054
127regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO2.40971354
128multicellular organismal signaling (GO:0035637)2.39468230
129regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314)2.38752579
130behavioral response to ethanol (GO:0048149)2.38446023
131mitochondrion transport along microtubule (GO:0047497)2.38315094
132establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.38315094
133establishment of nucleus localization (GO:0040023)2.37672189
134cardiac muscle hypertrophy in response to stress (GO:0014898)2.35498736
135muscle hypertrophy in response to stress (GO:0003299)2.35498736
136cardiac muscle adaptation (GO:0014887)2.35498736
137cardiac muscle cell development (GO:0055013)2.35111358
138behavioral response to cocaine (GO:0048148)2.35030239
139retinal ganglion cell axon guidance (GO:0031290)2.35012979
140adult walking behavior (GO:0007628)2.33935800
141regulation of cardioblast differentiation (GO:0051890)2.33602127
142regulation of membrane repolarization (GO:0060306)2.33516349

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.69716760
2GBX2_23144817_ChIP-Seq_PC3_Human4.12792557
3SUZ12_18555785_ChIP-Seq_MESCs_Mouse3.25698461
4SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.25115158
5JARID2_20064375_ChIP-Seq_MESCs_Mouse3.18744642
6SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.85994661
7SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.70759363
8EZH2_18974828_ChIP-Seq_MESCs_Mouse2.70190942
9RNF2_18974828_ChIP-Seq_MESCs_Mouse2.70190942
10JARID2_20075857_ChIP-Seq_MESCs_Mouse2.68100535
11EZH2_27304074_Chip-Seq_ESCs_Mouse2.56560849
12SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.55871738
13MTF2_20144788_ChIP-Seq_MESCs_Mouse2.50699380
14REST_21632747_ChIP-Seq_MESCs_Mouse2.49173532
15EED_16625203_ChIP-ChIP_MESCs_Mouse2.46462293
16* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.42135381
17ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.36473849
18RARB_27405468_Chip-Seq_BRAIN_Mouse2.18691017
19RNF2_27304074_Chip-Seq_ESCs_Mouse2.17515777
20EZH2_27294783_Chip-Seq_ESCs_Mouse2.17217910
21* SUZ12_27294783_Chip-Seq_ESCs_Mouse2.16428666
22IKZF1_21737484_ChIP-ChIP_HCT116_Human2.14156625
23* CTBP1_25329375_ChIP-Seq_LNCAP_Human2.13264393
24* CTBP2_25329375_ChIP-Seq_LNCAP_Human2.10317359
25DROSHA_22980978_ChIP-Seq_HELA_Human2.06350822
26REST_18959480_ChIP-ChIP_MESCs_Mouse2.02138565
27TAF15_26573619_Chip-Seq_HEK293_Human1.98841649
28* ZFP57_27257070_Chip-Seq_ESCs_Mouse1.90506680
29SMAD4_21799915_ChIP-Seq_A2780_Human1.86547200
30AR_21572438_ChIP-Seq_LNCaP_Human1.85421724
31CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.84477026
32* P300_19829295_ChIP-Seq_ESCs_Human1.73626970
33SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.73240515
34GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.70377627
35MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.62965037
36* PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.61376882
37PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.59548529
38GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.55673995
39PIAS1_25552417_ChIP-Seq_VCAP_Human1.52934261
40RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.52864836
41* AR_25329375_ChIP-Seq_VCAP_Human1.50952268
42* CBX2_27304074_Chip-Seq_ESCs_Mouse1.49180732
43* FUS_26573619_Chip-Seq_HEK293_Human1.47363750
44TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.44889426
45* SMAD3_21741376_ChIP-Seq_EPCs_Human1.44004479
46TOP2B_26459242_ChIP-Seq_MCF-7_Human1.43984474
47NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.43973425
48POU3F2_20337985_ChIP-ChIP_501MEL_Human1.43828820
49TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.43195578
50* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.41151660
51EP300_21415370_ChIP-Seq_HL-1_Mouse1.39000638
52* SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.38883804
53* ZNF274_21170338_ChIP-Seq_K562_Hela1.37545869
54SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.36719030
55ERG_21242973_ChIP-ChIP_JURKAT_Human1.35850569
56NR3C1_23031785_ChIP-Seq_PC12_Mouse1.34736466
57SMAD_19615063_ChIP-ChIP_OVARY_Human1.34416810
58SOX2_21211035_ChIP-Seq_LN229_Gbm1.33873652
59VDR_22108803_ChIP-Seq_LS180_Human1.29953282
60RING1B_27294783_Chip-Seq_ESCs_Mouse1.29701217
61BMI1_23680149_ChIP-Seq_NPCS_Mouse1.29066943
62TP53_18474530_ChIP-ChIP_U2OS_Human1.26025881
63LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.25281713
64ARNT_22903824_ChIP-Seq_MCF-7_Human1.23241165
65SALL1_21062744_ChIP-ChIP_HESCs_Human1.22798523
66STAT3_23295773_ChIP-Seq_U87_Human1.22217996
67* TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.22207302
68UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.20246541
69SMAD3_21741376_ChIP-Seq_HESCs_Human1.19607035
70AR_19668381_ChIP-Seq_PC3_Human1.16437684
71* AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.16396591
72EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.15593247
73EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.15478261
74ZNF217_24962896_ChIP-Seq_MCF-7_Human1.14445488
75KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.13674442
76TCF4_23295773_ChIP-Seq_U87_Human1.13154048
77RNF2_27304074_Chip-Seq_NSC_Mouse1.12744136
78STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.12140410
79SMAD4_21741376_ChIP-Seq_HESCs_Human1.11659740
80AHR_22903824_ChIP-Seq_MCF-7_Human1.11559998
81TP53_16413492_ChIP-PET_HCT116_Human1.11431945
82HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.10305555
83E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.10046122
84P53_22387025_ChIP-Seq_ESCs_Mouse1.09204322
85* EWS_26573619_Chip-Seq_HEK293_Human1.07752442
86WT1_19549856_ChIP-ChIP_CCG9911_Human1.07426116
87RING1B_27294783_Chip-Seq_NPCs_Mouse1.07033714
88IGF1R_20145208_ChIP-Seq_DFB_Human1.06778846
89* PRDM14_20953172_ChIP-Seq_ESCs_Human1.06583738
90* TAL1_26923725_Chip-Seq_HPCs_Mouse1.06335318
91CDX2_19796622_ChIP-Seq_MESCs_Mouse1.06320117
92E2F1_18555785_Chip-Seq_ESCs_Mouse1.05489588
93* RUNX2_22187159_ChIP-Seq_PCA_Human1.05195390
94* FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.05144272
95NR3C1_21868756_ChIP-Seq_MCF10A_Human1.04107032
96* ER_23166858_ChIP-Seq_MCF-7_Human1.03848624
97* YAP1_20516196_ChIP-Seq_MESCs_Mouse1.02907156
98WT1_25993318_ChIP-Seq_PODOCYTE_Human1.02010299
99* JUN_21703547_ChIP-Seq_K562_Human1.01821826
100TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.01475397
101* KDM2B_26808549_Chip-Seq_REH_Human1.01259174
102CMYC_18555785_Chip-Seq_ESCs_Mouse1.01234056
103* KLF5_20875108_ChIP-Seq_MESCs_Mouse1.01109960
104RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.01064006
105BCAT_22108803_ChIP-Seq_LS180_Human1.00058824
106CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.98566377
107NANOG_18555785_Chip-Seq_ESCs_Mouse0.98507261
108MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.97873591
109RXR_22108803_ChIP-Seq_LS180_Human0.95603333
110RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.95343536
111P53_22127205_ChIP-Seq_FIBROBLAST_Human0.95178354
112* CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.93695841
113POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.91162766
114TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.91162766
115TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.90303938
116MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.89932384
117PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.88739549
118MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.88549547
119WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.88268784
120IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.87598033
121CBP_20019798_ChIP-Seq_JUKART_Human0.87598033

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity6.94507663
2MP0003880_abnormal_central_pattern5.82163740
3MP0003635_abnormal_synaptic_transmissio4.23829362
4MP0009745_abnormal_behavioral_response3.67991111
5MP0002063_abnormal_learning/memory/cond3.49861945
6MP0002822_catalepsy3.34199041
7MP0002064_seizures3.29944023
8MP0004270_analgesia3.20914301
9MP0002572_abnormal_emotion/affect_behav2.97143230
10MP0001968_abnormal_touch/_nociception2.81512178
11MP0009046_muscle_twitch2.66046629
12MP0002735_abnormal_chemical_nociception2.64080915
13MP0001501_abnormal_sleep_pattern2.55328717
14MP0002272_abnormal_nervous_system2.54690442
15MP0001486_abnormal_startle_reflex2.49849723
16MP0002736_abnormal_nociception_after2.42824250
17MP0005423_abnormal_somatic_nervous2.37113015
18MP0009780_abnormal_chondrocyte_physiolo2.28386900
19MP0003329_amyloid_beta_deposits2.22510909
20MP0001440_abnormal_grooming_behavior2.20307364
21MP0002734_abnormal_mechanical_nocicepti2.11978257
22MP0003879_abnormal_hair_cell2.11731960
23MP0000566_synostosis1.97704902
24MP0002067_abnormal_sensory_capabilities1.95275026
25MP0005187_abnormal_penis_morphology1.83902792
26MP0000778_abnormal_nervous_system1.81446380
27MP0002184_abnormal_innervation1.79302353
28MP0002733_abnormal_thermal_nociception1.76576239
29MP0004858_abnormal_nervous_system1.74231289
30MP0001970_abnormal_pain_threshold1.62973731
31MP0005499_abnormal_olfactory_system1.62364567
32MP0005394_taste/olfaction_phenotype1.62364567
33MP0003787_abnormal_imprinting1.61785850
34MP0002557_abnormal_social/conspecific_i1.59860988
35MP0006276_abnormal_autonomic_nervous1.59021214
36MP0002638_abnormal_pupillary_reflex1.58661092
37MP0004811_abnormal_neuron_physiology1.58022653
38MP0002653_abnormal_ependyma_morphology1.57967566
39MP0008569_lethality_at_weaning1.57219429
40MP0005646_abnormal_pituitary_gland1.55291272
41MP0003283_abnormal_digestive_organ1.53404559
42MP0002163_abnormal_gland_morphology1.52202639
43MP0004043_abnormal_pH_regulation1.46048586
44MP0005386_behavior/neurological_phenoty1.44033970
45MP0004924_abnormal_behavior1.44033970
46MP0004885_abnormal_endolymph1.40484102
47MP0003890_abnormal_embryonic-extraembry1.39329741
48MP0002882_abnormal_neuron_morphology1.39198403
49MP0002909_abnormal_adrenal_gland1.36459302
50MP0000955_abnormal_spinal_cord1.35176511
51MP0002066_abnormal_motor_capabilities/c1.32876761
52MP0001502_abnormal_circadian_rhythm1.32393325
53MP0002837_dystrophic_cardiac_calcinosis1.28886515
54MP0005171_absent_coat_pigmentation1.26833121
55MP0001905_abnormal_dopamine_level1.25887723
56MP0005248_abnormal_Harderian_gland1.23287623
57MP0005379_endocrine/exocrine_gland_phen1.20262553
58MP0001984_abnormal_olfaction1.19262506
59MP0002233_abnormal_nose_morphology1.18992869
60MP0003633_abnormal_nervous_system1.18082505
61MP0004142_abnormal_muscle_tone1.17707151
62MP0001529_abnormal_vocalization1.17082388
63MP0003631_nervous_system_phenotype1.11664344
64MP0000604_amyloidosis1.10525743
65MP0001963_abnormal_hearing_physiology1.09055984
66MP0008789_abnormal_olfactory_epithelium1.08867107
67MP0000751_myopathy1.07125160
68MP0005645_abnormal_hypothalamus_physiol1.06481895
69MP0000462_abnormal_digestive_system1.06231133
70MP0003121_genomic_imprinting1.05950843
71MP0003122_maternal_imprinting1.05755399
72MP0002152_abnormal_brain_morphology1.04677489
73MP0004133_heterotaxia1.04375932
74MP0002876_abnormal_thyroid_physiology1.04134071
75MP0004782_abnormal_surfactant_physiolog1.03975777
76MP0004742_abnormal_vestibular_system1.02995888
77MP0003136_yellow_coat_color1.02011980
78MP0001188_hyperpigmentation1.01949482
79MP0000569_abnormal_digit_pigmentation1.00496047
80MP0001299_abnormal_eye_distance/0.99554102
81MP0002234_abnormal_pharynx_morphology0.98706871
82MP0003632_abnormal_nervous_system0.98477838
83MP0010386_abnormal_urinary_bladder0.97918792
84MP0001485_abnormal_pinna_reflex0.93736009
85MP0000537_abnormal_urethra_morphology0.93183641
86MP0002069_abnormal_eating/drinking_beha0.91752789
87MP0004215_abnormal_myocardial_fiber0.91380536
88MP0004484_altered_response_of0.90922267
89MP0005551_abnormal_eye_electrophysiolog0.90696385
90MP0005253_abnormal_eye_physiology0.90528953
91MP0003075_altered_response_to0.89999610
92MP0004084_abnormal_cardiac_muscle0.89302299
93MP0004085_abnormal_heartbeat0.85535339
94MP0000026_abnormal_inner_ear0.83748999
95MP0002229_neurodegeneration0.83194376
96MP0008775_abnormal_heart_ventricle0.81895402
97MP0002938_white_spotting0.81757434
98MP0001177_atelectasis0.81463787
99MP0004145_abnormal_muscle_electrophysio0.80306438
100MP0002752_abnormal_somatic_nervous0.79134314
101MP0003690_abnormal_glial_cell0.76722131
102MP0003937_abnormal_limbs/digits/tail_de0.76150299
103MP0003119_abnormal_digestive_system0.75756379
104MP0003634_abnormal_glial_cell0.75325612
105MP0005220_abnormal_exocrine_pancreas0.73696841
106MP0008874_decreased_physiological_sensi0.73298956
107MP0003567_abnormal_fetal_cardiomyocyte0.72026727
108MP0000534_abnormal_ureter_morphology0.70397826
109MP0010234_abnormal_vibrissa_follicle0.69754459
110MP0001664_abnormal_digestion0.66081996
111MP0000013_abnormal_adipose_tissue0.65979304
112MP0005595_abnormal_vascular_smooth0.65568525
113MP0003938_abnormal_ear_development0.63691680
114MP0003123_paternal_imprinting0.61673420
115MP0006292_abnormal_olfactory_placode0.61513339
116MP0005535_abnormal_body_temperature0.61484539
117MP0008872_abnormal_physiological_respon0.61446210
118MP0005623_abnormal_meninges_morphology0.60820919
119MP0000631_abnormal_neuroendocrine_gland0.59286831
120MP0003137_abnormal_impulse_conducting0.58840489
121MP0000920_abnormal_myelination0.56111603
122MP0008877_abnormal_DNA_methylation0.54881348
123MP0003861_abnormal_nervous_system0.54820537
124MP0002090_abnormal_vision0.54571015
125MP0001943_abnormal_respiration0.51942330
126MP0003172_abnormal_lysosome_physiology0.51546544
127MP0004510_myositis0.50621116
128MP0005409_darkened_coat_color0.47401721
129MP0010769_abnormal_survival0.46160374
130MP0010770_preweaning_lethality0.46089164
131MP0002082_postnatal_lethality0.46089164
132MP0001765_abnormal_ion_homeostasis0.44643235

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)9.20386957
2Focal seizures (HP:0007359)5.88301356
3Myokymia (HP:0002411)5.87995610
4Atonic seizures (HP:0010819)5.49491140
5Epileptic encephalopathy (HP:0200134)5.41220076
6Hyperventilation (HP:0002883)5.26882917
7Visual hallucinations (HP:0002367)5.14297330
8Febrile seizures (HP:0002373)4.94256569
9Absence seizures (HP:0002121)4.86955488
10Dialeptic seizures (HP:0011146)4.71536599
11Progressive cerebellar ataxia (HP:0002073)4.31916205
12Generalized tonic-clonic seizures (HP:0002069)4.09990788
13Broad-based gait (HP:0002136)3.64138518
14Action tremor (HP:0002345)3.54712949
15Excessive salivation (HP:0003781)3.53264556
16Drooling (HP:0002307)3.53264556
17Cerebral inclusion bodies (HP:0100314)3.41154397
18Dysdiadochokinesis (HP:0002075)3.30540394
19Amblyopia (HP:0000646)3.22687482
20Gaze-evoked nystagmus (HP:0000640)3.18063896
21Limb dystonia (HP:0002451)3.13162237
22Poor eye contact (HP:0000817)3.07718722
23Dysmetria (HP:0001310)3.05605740
24Neurofibrillary tangles (HP:0002185)3.05252768
25Impaired vibration sensation in the lower limbs (HP:0002166)3.01067386
26Truncal ataxia (HP:0002078)3.00304534
27Absent speech (HP:0001344)2.98791137
28Abnormality of the lower motor neuron (HP:0002366)2.88677899
29Supranuclear gaze palsy (HP:0000605)2.88022108
30Epileptiform EEG discharges (HP:0011182)2.87178998
31Congenital malformation of the right heart (HP:0011723)2.83470859
32Double outlet right ventricle (HP:0001719)2.83470859
33Abnormal social behavior (HP:0012433)2.82263382
34Impaired social interactions (HP:0000735)2.82263382
35Abnormal eating behavior (HP:0100738)2.81691135
36Depression (HP:0000716)2.81008141
37Anxiety (HP:0000739)2.73503442
38Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.71758202
39Fetal akinesia sequence (HP:0001989)2.69346677
40Postural instability (HP:0002172)2.64816135
41Syncope (HP:0001279)2.60941432
42Mutism (HP:0002300)2.59922494
43Sleep apnea (HP:0010535)2.58220421
44Abnormal pancreas size (HP:0012094)2.57457015
45Failure to thrive in infancy (HP:0001531)2.56022856
46Hemiparesis (HP:0001269)2.53398683
47EEG with generalized epileptiform discharges (HP:0011198)2.52544972
48Abnormal respiratory motile cilium physiology (HP:0012261)2.51500759
49Protruding tongue (HP:0010808)2.51415816
50Stereotypic behavior (HP:0000733)2.50040041
51Abnormal ciliary motility (HP:0012262)2.49769956
52Congenital sensorineural hearing impairment (HP:0008527)2.49353449
53Abnormality of binocular vision (HP:0011514)2.47979897
54Diplopia (HP:0000651)2.47979897
55Progressive inability to walk (HP:0002505)2.45203945
56Nephrogenic diabetes insipidus (HP:0009806)2.44960236
57Abnormal respiratory motile cilium morphology (HP:0005938)2.42775580
58Abnormal respiratory epithelium morphology (HP:0012253)2.42775580
59Dynein arm defect of respiratory motile cilia (HP:0012255)2.42237709
60Absent/shortened dynein arms (HP:0200106)2.42237709
61Vaginal atresia (HP:0000148)2.42132377
62Hemiplegia (HP:0002301)2.40690100
63Abnormality of salivation (HP:0100755)2.39298701
64Thickened helices (HP:0000391)2.37619345
65Generalized myoclonic seizures (HP:0002123)2.37341585
66Scanning speech (HP:0002168)2.34343899
67Inability to walk (HP:0002540)2.32432989
68Urinary bladder sphincter dysfunction (HP:0002839)2.32039200
69Genital tract atresia (HP:0001827)2.31995691
70Rhinitis (HP:0012384)2.31450367
71Blue irides (HP:0000635)2.29861494
72Hypsarrhythmia (HP:0002521)2.28880021
73Shawl scrotum (HP:0000049)2.26951552
74Specific learning disability (HP:0001328)2.25481752
75Abnormality of the aortic arch (HP:0012303)2.25058604
76Atrial fibrillation (HP:0005110)2.24540489
77Primary atrial arrhythmia (HP:0001692)2.20491950
78Impaired smooth pursuit (HP:0007772)2.20392503
79Cortical dysplasia (HP:0002539)2.19273379
80Bradykinesia (HP:0002067)2.18898949
81Status epilepticus (HP:0002133)2.16856268
82Genetic anticipation (HP:0003743)2.15129481
83Polyphagia (HP:0002591)2.14283236
84Rib fusion (HP:0000902)2.14029530
85Widely spaced teeth (HP:0000687)2.10260564
86Intention tremor (HP:0002080)2.09575408
87Dysmetric saccades (HP:0000641)2.09093283
88Akinesia (HP:0002304)2.06810927
89Supraventricular tachycardia (HP:0004755)2.06747061
90Poor coordination (HP:0002370)2.06529086
91Delusions (HP:0000746)2.05710885
92Left ventricular hypertrophy (HP:0001712)2.04897112
93Gait imbalance (HP:0002141)2.04441836
94Torticollis (HP:0000473)2.04391941
95Impaired vibratory sensation (HP:0002495)2.02875093
96Fair hair (HP:0002286)2.01807668
97Decreased number of large peripheral myelinated nerve fibers (HP:0003387)2.00569022
98Focal dystonia (HP:0004373)2.00307435
99Supraventricular arrhythmia (HP:0005115)2.00007950
100Termporal pattern (HP:0011008)1.99545060
101Insidious onset (HP:0003587)1.99545060
102Abnormal EKG (HP:0003115)1.99341456
103Gait ataxia (HP:0002066)1.98090315
104Abnormality of ocular smooth pursuit (HP:0000617)1.96647001
105Incomplete penetrance (HP:0003829)1.95324638
106Spastic gait (HP:0002064)1.94785974
107Sudden death (HP:0001699)1.94637631
108Prolonged QT interval (HP:0001657)1.94198209
109Abnormality of the corticospinal tract (HP:0002492)1.91329815
110Megalencephaly (HP:0001355)1.89975042
111Urinary urgency (HP:0000012)1.87249981
112Hyperthyroidism (HP:0000836)1.87238604
113Amyotrophic lateral sclerosis (HP:0007354)1.87128524
114Obstructive sleep apnea (HP:0002870)1.86355267
115Increased circulating renin level (HP:0000848)1.86189437
116Nephronophthisis (HP:0000090)1.84413527
117Inappropriate behavior (HP:0000719)1.83590252
118Retinal dysplasia (HP:0007973)1.83127168
119Decreased circulating renin level (HP:0003351)1.83114249
120Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.81762656
121Degeneration of the lateral corticospinal tracts (HP:0002314)1.81762656
122Generalized hypopigmentation of hair (HP:0011358)1.80969184
123Type II lissencephaly (HP:0007260)1.79874204
124Cutaneous finger syndactyly (HP:0010554)1.79520704
125Bundle branch block (HP:0011710)1.78783224
126Intestinal atresia (HP:0011100)1.77877676
127Spastic tetraplegia (HP:0002510)1.77720661
128Agitation (HP:0000713)1.77463036
129Rapidly progressive (HP:0003678)1.76933204
130Clumsiness (HP:0002312)1.76405198
131Ankle clonus (HP:0011448)1.75910764
132Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026)1.74006738
133Short 1st metacarpal (HP:0010034)1.74006738
134Psychosis (HP:0000709)1.73758664
135Esotropia (HP:0000565)1.73490546
136Lower limb asymmetry (HP:0100559)1.72879328
137Congenital primary aphakia (HP:0007707)1.72076434
138Lower limb muscle weakness (HP:0007340)1.71275599
139Postaxial hand polydactyly (HP:0001162)1.70024799
140Hypoventilation (HP:0002791)1.69820509
141Labial hypoplasia (HP:0000066)1.67883393
142Occipital encephalocele (HP:0002085)1.67712821
143Athetosis (HP:0002305)1.67011343
144Medial flaring of the eyebrow (HP:0010747)1.65285953
145Gastroesophageal reflux (HP:0002020)1.65270082
146Turricephaly (HP:0000262)1.64329676
147Craniofacial dystonia (HP:0012179)1.63678189
148Muscular hypotonia of the trunk (HP:0008936)1.63408804
149Male infertility (HP:0003251)1.60564525
150Chronic bronchitis (HP:0004469)1.59948706
151Aplasia involving bones of the upper limbs (HP:0009823)1.57616121
152Aplasia of the phalanges of the hand (HP:0009802)1.57616121
153Aplasia involving bones of the extremities (HP:0009825)1.57616121
154Tubulointerstitial nephritis (HP:0001970)1.56150716
155True hermaphroditism (HP:0010459)1.55790020
156Abnormality of the 1st metacarpal (HP:0010009)1.55559138
157Hand muscle atrophy (HP:0009130)1.55313967

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NTRK35.39867850
2EPHA45.38180256
3CASK3.60451390
4MAP3K93.37160338
5EPHA33.26135074
6MAP3K42.47695018
7TRIM282.39454050
8MAP2K72.30975009
9PLK22.30965261
10MINK12.29060687
11MARK12.25564455
12TNIK2.20613784
13RIPK42.12290533
14PRPF4B2.08641040
15KSR21.97634540
16DAPK21.90668125
17NTRK21.90662396
18MAP3K121.90578093
19KSR11.84117152
20DYRK21.75963344
21MAP4K21.73380312
22FRK1.72906978
23DAPK11.68036493
24MAP3K131.67158263
25MAP2K41.62988305
26PAK61.60773368
27ARAF1.58429866
28PTK2B1.55542508
29PNCK1.52451929
30GRK51.48252885
31BCR1.46594783
32PRKCG1.43884212
33CDK51.40024390
34LATS11.37004126
35NTRK11.32199445
36CAMK2A1.30724180
37CAMK2B1.27746220
38SIK21.27729795
39TAOK11.27584585
40STK38L1.26122847
41CAMKK11.25996166
42FES1.20746119
43PRKD31.18093123
44MAPK131.16737798
45CSNK1G31.15624188
46CAMK11.14359365
47CSNK1G11.13957019
48NME11.13565500
49CAMKK21.10018390
50CSNK1A1L1.09618745
51FGFR21.08360804
52WNK31.05625796
53BMPR21.04648761
54RAF11.02676434
55CCNB11.01845502
56STK380.99860474
57PHKG10.95476647
58PHKG20.95476647
59FGR0.94128113
60LIMK10.91672580
61EPHB10.86813615
62LMTK20.78955244
63SGK4940.78782163
64SGK2230.78782163
65BMPR1B0.78515276
66SIK30.78293702
67DYRK1A0.77618424
68CDK180.77453054
69CDK140.74916000
70SGK20.74549800
71FER0.73612622
72CDK150.73558950
73CDK190.72751064
74STK30.72695422
75PRKCH0.71969138
76MAP3K20.71510614
77PRKCE0.71461649
78UHMK10.70961969
79SGK10.69504144
80PAK30.68739173
81EIF2AK10.68489334
82ACVR1B0.68118338
83GRK10.64583679
84OBSCN0.63106304
85AKT30.62843989
86PRKAA10.62829493
87CAMK2D0.62442055
88CDK11A0.62154508
89ADRBK10.62139863
90MST40.62009078
91MAP3K70.59910888
92PIK3CA0.59290807
93MKNK20.54903580
94CDK30.54687688
95CAMK1G0.54680550
96LATS20.54447656
97TYRO30.53939528
98BRAF0.53928867
99DMPK0.53570682
100CSNK1A10.53053188
101OXSR10.51857483
102MARK20.51672147
103GRK60.50963717
104MYLK0.50521728
105PRKG10.49559842
106CAMK2G0.48209279
107PDK10.48102313
108STK110.47260760
109BRSK10.45948266
110SGK30.45737392
111MAP2K10.45406342
112MAP3K10.44457244
113BRSK20.44215583
114PDPK10.44123995
115NEK10.43952289
116CSNK1G20.43702111
117ROCK10.43211799
118ROCK20.43163153
119MAPK120.42146463
120RPS6KA30.41115460
121FYN0.40942408
122PRKCZ0.40772528
123CAMK40.39779633
124MAP3K60.39519086
125RET0.39377578
126MOS0.38308875
127PKN10.38209765
128PRKG20.37886693
129MUSK0.36898711
130BCKDK0.36209225
131PRKCA0.35688730
132PRKACA0.34546298
133MAPK100.34456177
134PINK10.33661073
135ERBB30.31910953
136PRKCB0.31555956

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050334.63626727
2Retrograde endocannabinoid signaling_Homo sapiens_hsa047233.08035227
3Long-term potentiation_Homo sapiens_hsa047202.96803689
4Synaptic vesicle cycle_Homo sapiens_hsa047212.96328769
5Circadian entrainment_Homo sapiens_hsa047132.87871667
6GABAergic synapse_Homo sapiens_hsa047272.75073045
7Glutamatergic synapse_Homo sapiens_hsa047242.73425884
8Amphetamine addiction_Homo sapiens_hsa050312.53340583
9Morphine addiction_Homo sapiens_hsa050322.51830747
10Olfactory transduction_Homo sapiens_hsa047402.36839102
11Salivary secretion_Homo sapiens_hsa049702.32132610
12Dopaminergic synapse_Homo sapiens_hsa047282.13534554
13Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.03284120
14Collecting duct acid secretion_Homo sapiens_hsa049662.01489398
15Taste transduction_Homo sapiens_hsa047422.00347830
16Long-term depression_Homo sapiens_hsa047301.92892173
17Serotonergic synapse_Homo sapiens_hsa047261.92446208
18Insulin secretion_Homo sapiens_hsa049111.88089685
19Calcium signaling pathway_Homo sapiens_hsa040201.86376345
20Gastric acid secretion_Homo sapiens_hsa049711.82379250
21Cholinergic synapse_Homo sapiens_hsa047251.76061543
22Maturity onset diabetes of the young_Homo sapiens_hsa049501.70188098
23Aldosterone synthesis and secretion_Homo sapiens_hsa049251.69603917
24Oxytocin signaling pathway_Homo sapiens_hsa049211.68129374
25Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.65032477
26Renin secretion_Homo sapiens_hsa049241.61186637
27Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.58372640
28Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.47053365
29Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.42949493
30GnRH signaling pathway_Homo sapiens_hsa049121.37175160
31Cocaine addiction_Homo sapiens_hsa050301.30537511
32cAMP signaling pathway_Homo sapiens_hsa040241.30509168
33Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.27909919
34Vibrio cholerae infection_Homo sapiens_hsa051101.26390014
35Axon guidance_Homo sapiens_hsa043601.24978523
36Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.20512549
37Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.18800984
38Gap junction_Homo sapiens_hsa045401.18708698
39Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.15625193
40Glioma_Homo sapiens_hsa052141.12758468
41Tight junction_Homo sapiens_hsa045301.12357231
42Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.08982809
43Estrogen signaling pathway_Homo sapiens_hsa049151.08782906
44Cardiac muscle contraction_Homo sapiens_hsa042601.08223792
45cGMP-PKG signaling pathway_Homo sapiens_hsa040221.07920266
46Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.07900228
47Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.05267203
48Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.04889988
49Melanogenesis_Homo sapiens_hsa049161.02983346
50Phosphatidylinositol signaling system_Homo sapiens_hsa040700.98548595
51ErbB signaling pathway_Homo sapiens_hsa040120.96321542
52Vascular smooth muscle contraction_Homo sapiens_hsa042700.93185402
53Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.90891726
54Hippo signaling pathway_Homo sapiens_hsa043900.90680717
55Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.89866371
56Butanoate metabolism_Homo sapiens_hsa006500.88691435
57Protein export_Homo sapiens_hsa030600.88134750
58Pancreatic secretion_Homo sapiens_hsa049720.87566845
59Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.87441740
60Type II diabetes mellitus_Homo sapiens_hsa049300.85122704
61Choline metabolism in cancer_Homo sapiens_hsa052310.81936940
62Dilated cardiomyopathy_Homo sapiens_hsa054140.80048609
63Fatty acid metabolism_Homo sapiens_hsa012120.78979148
64Phospholipase D signaling pathway_Homo sapiens_hsa040720.76858494
65Propanoate metabolism_Homo sapiens_hsa006400.75156088
66Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.74735349
67Oocyte meiosis_Homo sapiens_hsa041140.74688777
68Dorso-ventral axis formation_Homo sapiens_hsa043200.74421215
69Steroid biosynthesis_Homo sapiens_hsa001000.72082400
70Thyroid hormone synthesis_Homo sapiens_hsa049180.71840030
71Fatty acid elongation_Homo sapiens_hsa000620.67083290
72Vitamin B6 metabolism_Homo sapiens_hsa007500.66907151
73Phototransduction_Homo sapiens_hsa047440.66822775
74Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.66197081
75Alzheimers disease_Homo sapiens_hsa050100.64073354
76Sulfur metabolism_Homo sapiens_hsa009200.63882494
77Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.63295696
78Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.63244190
79MAPK signaling pathway_Homo sapiens_hsa040100.62923796
80Sphingolipid metabolism_Homo sapiens_hsa006000.62414009
81Selenocompound metabolism_Homo sapiens_hsa004500.62295753
82Histidine metabolism_Homo sapiens_hsa003400.61768738
83Hedgehog signaling pathway_Homo sapiens_hsa043400.61571672
84ABC transporters_Homo sapiens_hsa020100.61565205
85Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.59936842
86Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.59704030
87Glucagon signaling pathway_Homo sapiens_hsa049220.57603657
88Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.57526643
89Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.57448630
90African trypanosomiasis_Homo sapiens_hsa051430.56309638
91Oxidative phosphorylation_Homo sapiens_hsa001900.56030188
92Rap1 signaling pathway_Homo sapiens_hsa040150.55100724
93Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.54937158
94Ras signaling pathway_Homo sapiens_hsa040140.54862583
95Carbohydrate digestion and absorption_Homo sapiens_hsa049730.54097488
96VEGF signaling pathway_Homo sapiens_hsa043700.54064569
97Fatty acid degradation_Homo sapiens_hsa000710.53765573
98Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.53122673
99Type I diabetes mellitus_Homo sapiens_hsa049400.52750051
100Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.51278611
101Huntingtons disease_Homo sapiens_hsa050160.46646118
102Pyruvate metabolism_Homo sapiens_hsa006200.46559856
103Rheumatoid arthritis_Homo sapiens_hsa053230.46463332
104Regulation of autophagy_Homo sapiens_hsa041400.46305734
105Wnt signaling pathway_Homo sapiens_hsa043100.46204000
106Primary bile acid biosynthesis_Homo sapiens_hsa001200.46079057
107Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.46047574
108Ether lipid metabolism_Homo sapiens_hsa005650.45479328
109Arginine and proline metabolism_Homo sapiens_hsa003300.44368688
110beta-Alanine metabolism_Homo sapiens_hsa004100.42901365
111Adherens junction_Homo sapiens_hsa045200.42839427
112Neurotrophin signaling pathway_Homo sapiens_hsa047220.42832231
113Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.42179393
114Bile secretion_Homo sapiens_hsa049760.38270452
115Prion diseases_Homo sapiens_hsa050200.36933390
116Circadian rhythm_Homo sapiens_hsa047100.35936443
117Nitrogen metabolism_Homo sapiens_hsa009100.35566085
118Sphingolipid signaling pathway_Homo sapiens_hsa040710.35333403
119Thyroid hormone signaling pathway_Homo sapiens_hsa049190.35013780
120Alcoholism_Homo sapiens_hsa050340.33639361
121Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.27981477
122Inositol phosphate metabolism_Homo sapiens_hsa005620.26833978
123Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.25199278
124Ovarian steroidogenesis_Homo sapiens_hsa049130.24753286
125Mineral absorption_Homo sapiens_hsa049780.23583396
126Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.22826291
127Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.22754253
128Fatty acid biosynthesis_Homo sapiens_hsa000610.21169439
129Regulation of actin cytoskeleton_Homo sapiens_hsa048100.20959941
130Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.20526524
131Non-small cell lung cancer_Homo sapiens_hsa052230.19960260
132Phagosome_Homo sapiens_hsa041450.19820021
133Endocytosis_Homo sapiens_hsa041440.19494129
134Renal cell carcinoma_Homo sapiens_hsa052110.18984660
135Insulin signaling pathway_Homo sapiens_hsa049100.17256680

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