PCDH8

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The gene encodes an integral membrane protein that is thought to function in cell adhesion in a CNS-specific manner. Unlike classical cadherins, which are generally encoded by 15-17 exons, this gene includes only 3 exons. Notable is the large first exon encoding the extracellular region, including 6 cadherin domains and a transmembrane region. Alternative splicing yields isoforms with unique cytoplasmic tails. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of short-term neuronal synaptic plasticity (GO:0048172)6.30034819
2vocalization behavior (GO:0071625)6.07648176
3protein localization to synapse (GO:0035418)5.96213178
4positive regulation of excitatory postsynaptic membrane potential (GO:2000463)5.57602991
5ionotropic glutamate receptor signaling pathway (GO:0035235)5.48798631
6positive regulation of synapse maturation (GO:0090129)5.47895565
7regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act5.38526612
8synaptic vesicle exocytosis (GO:0016079)5.25137645
9neuron cell-cell adhesion (GO:0007158)5.20119864
10glutamate receptor signaling pathway (GO:0007215)5.17059348
11nucleobase catabolic process (GO:0046113)5.11396068
12dendritic spine morphogenesis (GO:0060997)4.79907372
13synaptic transmission, glutamatergic (GO:0035249)4.78714400
14regulation of glutamate receptor signaling pathway (GO:1900449)4.76480900
15locomotory exploration behavior (GO:0035641)4.73603399
16neuron recognition (GO:0008038)4.69191119
17regulation of neuronal synaptic plasticity (GO:0048168)4.55404499
18glutamate secretion (GO:0014047)4.54432247
19synaptic vesicle maturation (GO:0016188)4.46441843
20regulation of long-term neuronal synaptic plasticity (GO:0048169)4.40989362
21G-protein coupled glutamate receptor signaling pathway (GO:0007216)4.40973506
22central nervous system projection neuron axonogenesis (GO:0021952)4.40709813
23positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.37757625
24regulation of synapse maturation (GO:0090128)4.37258622
25layer formation in cerebral cortex (GO:0021819)4.36706870
26neurotransmitter-gated ion channel clustering (GO:0072578)4.32774561
27neuron projection extension involved in neuron projection guidance (GO:1902284)4.29793430
28axon extension involved in axon guidance (GO:0048846)4.29793430
29behavioral defense response (GO:0002209)4.26597671
30behavioral fear response (GO:0001662)4.26597671
31transmission of nerve impulse (GO:0019226)4.26075351
32axonal fasciculation (GO:0007413)4.22548379
33dendrite morphogenesis (GO:0048813)4.17138357
34dendritic spine organization (GO:0097061)4.15635630
35regulation of synaptic vesicle exocytosis (GO:2000300)4.15381262
36gamma-aminobutyric acid transport (GO:0015812)4.13691889
37regulation of synapse structural plasticity (GO:0051823)4.13117846
38neuron-neuron synaptic transmission (GO:0007270)4.12762428
39cerebral cortex radially oriented cell migration (GO:0021799)4.12711803
40gamma-aminobutyric acid signaling pathway (GO:0007214)4.05756731
41regulation of excitatory postsynaptic membrane potential (GO:0060079)4.02797471
42exploration behavior (GO:0035640)4.02209185
43establishment of nucleus localization (GO:0040023)3.99446909
44positive regulation of dendritic spine morphogenesis (GO:0061003)3.96498962
45startle response (GO:0001964)3.93912179
46regulation of synaptic plasticity (GO:0048167)3.87915483
47negative regulation of synaptic transmission, GABAergic (GO:0032229)3.87395627
48fear response (GO:0042596)3.86114007
49regulation of synaptic vesicle transport (GO:1902803)3.84233927
50inner ear receptor cell development (GO:0060119)3.83675201
51regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.83474564
52proline transport (GO:0015824)3.83440679
53axon extension (GO:0048675)3.80487262
54regulation of postsynaptic membrane potential (GO:0060078)3.79780786
55long-term memory (GO:0007616)3.78925195
56postsynaptic membrane organization (GO:0001941)3.74153905
57positive regulation of membrane potential (GO:0045838)3.72474346
58establishment of mitochondrion localization (GO:0051654)3.71490986
59regulation of dendritic spine morphogenesis (GO:0061001)3.69627304
60presynaptic membrane assembly (GO:0097105)3.69203331
61negative regulation of amino acid transport (GO:0051956)3.63770760
62regulation of vesicle fusion (GO:0031338)3.60395342
63positive regulation of dendritic spine development (GO:0060999)3.59817277
64presynaptic membrane organization (GO:0097090)3.59489219
65neurotransmitter secretion (GO:0007269)3.58552642
66dendrite development (GO:0016358)3.57763678
67cellular sodium ion homeostasis (GO:0006883)3.55382292
68auditory behavior (GO:0031223)3.52469061
69central nervous system neuron axonogenesis (GO:0021955)3.51948166
70ephrin receptor signaling pathway (GO:0048013)3.48417809
71regulation of axon extension involved in axon guidance (GO:0048841)3.47997568
72learning (GO:0007612)3.47390311
73neuronal action potential propagation (GO:0019227)3.47243401
74regulation of glutamate secretion (GO:0014048)3.45027747
75regulation of axon guidance (GO:1902667)3.44488020
76response to auditory stimulus (GO:0010996)3.41894455
77synaptic vesicle docking involved in exocytosis (GO:0016081)3.35968741
78dopamine biosynthetic process (GO:0042416)3.32690676
79cerebellar Purkinje cell layer development (GO:0021680)3.32589761
80innervation (GO:0060384)3.32257749
81pyrimidine nucleobase catabolic process (GO:0006208)3.29867301
82regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.25970142
83neuron projection extension (GO:1990138)3.24999768
84cell migration in hindbrain (GO:0021535)3.21899633
85negative regulation of axon extension involved in axon guidance (GO:0048843)3.21571755
86regulation of synaptic transmission, glutamatergic (GO:0051966)3.21361195
87negative regulation of axon guidance (GO:1902668)3.20952601
88positive regulation of synapse assembly (GO:0051965)3.19392734
89cellular potassium ion homeostasis (GO:0030007)3.18713946
90regulation of synapse organization (GO:0050807)3.18118984
91associative learning (GO:0008306)3.17590414
92regulation of dendritic spine development (GO:0060998)3.17430361
93activation of protein kinase A activity (GO:0034199)3.16915359
94positive regulation of fibroblast migration (GO:0010763)3.14937979
95synapse assembly (GO:0007416)3.14731378
96membrane depolarization (GO:0051899)3.13473787
97serotonin metabolic process (GO:0042428)3.12250528
98regulation of synaptic transmission (GO:0050804)3.10854398
99negative regulation of neurotransmitter transport (GO:0051589)3.07526186
100negative chemotaxis (GO:0050919)3.06827203
101retinal ganglion cell axon guidance (GO:0031290)3.06812723
102cochlea development (GO:0090102)3.06730947
103regulation of synapse assembly (GO:0051963)3.06379447
104positive regulation of synaptic transmission, GABAergic (GO:0032230)3.05688796
105cerebellar granule cell differentiation (GO:0021707)3.05162314
106neuronal stem cell maintenance (GO:0097150)3.04441832
107negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.03798361
108membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.03364908
109neuromuscular process controlling balance (GO:0050885)3.01964465
110neurotransmitter transport (GO:0006836)3.01377759
111positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.00083136
112negative regulation of calcium ion-dependent exocytosis (GO:0045955)2.98745704
113prepulse inhibition (GO:0060134)2.96867600
114adult walking behavior (GO:0007628)2.93601655
115synaptic vesicle endocytosis (GO:0048488)2.91671487
116negative regulation of microtubule polymerization (GO:0031115)2.91418300
117mitochondrion transport along microtubule (GO:0047497)2.88483699
118establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.88483699
119lateral sprouting from an epithelium (GO:0060601)2.87887647
120neuromuscular synaptic transmission (GO:0007274)2.85392035
121mechanosensory behavior (GO:0007638)2.82520746
122spinal cord development (GO:0021510)2.81825721
123axonogenesis (GO:0007409)2.81790009
124response to amphetamine (GO:0001975)2.80081010
125behavioral response to nicotine (GO:0035095)2.79451995
126limb bud formation (GO:0060174)2.79182141
127synapse organization (GO:0050808)2.77396330
128regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.74205487
129adult behavior (GO:0030534)2.72175533
130negative regulation of axonogenesis (GO:0050771)2.70650237
131neuron migration (GO:0001764)2.69689078
132behavioral response to ethanol (GO:0048149)2.69060900
133regulation of neurotransmitter levels (GO:0001505)2.68546036
134adult locomotory behavior (GO:0008344)2.64396933
135regulation of neurotransmitter secretion (GO:0046928)2.64339629
136myotube differentiation (GO:0014902)2.64205541
137regulation of neurotransmitter transport (GO:0051588)2.62844521
138amino acid import (GO:0043090)2.61859708
139establishment of synaptic vesicle localization (GO:0097480)2.61395907
140synaptic vesicle transport (GO:0048489)2.61395907

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human7.98852294
2GBX2_23144817_ChIP-Seq_PC3_Human3.75708959
3RBPJ_22232070_ChIP-Seq_NCS_Mouse3.39392070
4* JARID2_20064375_ChIP-Seq_MESCs_Mouse3.36372095
5* SUZ12_18555785_ChIP-Seq_MESCs_Mouse3.22529098
6* SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.20739925
7* JARID2_20075857_ChIP-Seq_MESCs_Mouse2.89198728
8* RNF2_18974828_ChIP-Seq_MESCs_Mouse2.86757905
9* EZH2_18974828_ChIP-Seq_MESCs_Mouse2.86757905
10* SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.79087288
11* EZH2_27304074_Chip-Seq_ESCs_Mouse2.75948074
12* SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.74149078
13* SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.66056115
14* EED_16625203_ChIP-ChIP_MESCs_Mouse2.64293233
15* MTF2_20144788_ChIP-Seq_MESCs_Mouse2.49512863
16* REST_21632747_ChIP-Seq_MESCs_Mouse2.45572863
17* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.40930547
18* EZH2_27294783_Chip-Seq_ESCs_Mouse2.39306164
19* SUZ12_27294783_Chip-Seq_ESCs_Mouse2.37149138
20* RNF2_27304074_Chip-Seq_ESCs_Mouse2.35090383
21DROSHA_22980978_ChIP-Seq_HELA_Human2.33194181
22RARB_27405468_Chip-Seq_BRAIN_Mouse2.15329777
23AR_21572438_ChIP-Seq_LNCaP_Human2.10982360
24CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.05621240
25ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.01632421
26* REST_18959480_ChIP-ChIP_MESCs_Mouse1.94245414
27CTBP1_25329375_ChIP-Seq_LNCAP_Human1.93658651
28IKZF1_21737484_ChIP-ChIP_HCT116_Human1.92221679
29CTBP2_25329375_ChIP-Seq_LNCAP_Human1.90023997
30NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.80135503
31* PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.78051685
32CBX2_27304074_Chip-Seq_ESCs_Mouse1.71901075
33TAF15_26573619_Chip-Seq_HEK293_Human1.71248683
34* RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.70344625
35HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.68252662
36PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.64757549
37GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.64701848
38SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.60143620
39SMAD4_21799915_ChIP-Seq_A2780_Human1.51691989
40TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.51067803
41EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.49908017
42MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.48164249
43SMAD3_21741376_ChIP-Seq_EPCs_Human1.47269983
44* RING1B_27294783_Chip-Seq_ESCs_Mouse1.43713825
45* BMI1_23680149_ChIP-Seq_NPCS_Mouse1.41327655
46ZNF274_21170338_ChIP-Seq_K562_Hela1.40506697
47SALL1_21062744_ChIP-ChIP_HESCs_Human1.36905839
48ZFP57_27257070_Chip-Seq_ESCs_Mouse1.36319536
49SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.34542237
50P300_19829295_ChIP-Seq_ESCs_Human1.34321271
51ERG_21242973_ChIP-ChIP_JURKAT_Human1.33715224
52RING1B_27294783_Chip-Seq_NPCs_Mouse1.32265804
53KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.32063611
54POU5F1_16153702_ChIP-ChIP_HESCs_Human1.30735110
55SOX2_21211035_ChIP-Seq_LN229_Gbm1.30147194
56RNF2_27304074_Chip-Seq_NSC_Mouse1.27576357
57TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.27165424
58AR_25329375_ChIP-Seq_VCAP_Human1.26678573
59* MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.25310347
60PIAS1_25552417_ChIP-Seq_VCAP_Human1.24309193
61TOP2B_26459242_ChIP-Seq_MCF-7_Human1.23383298
62EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.22985509
63IGF1R_20145208_ChIP-Seq_DFB_Human1.20721133
64ARNT_22903824_ChIP-Seq_MCF-7_Human1.17016268
65CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.16351780
66OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.16254841
67LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.16211346
68AR_19668381_ChIP-Seq_PC3_Human1.16184915
69AHR_22903824_ChIP-Seq_MCF-7_Human1.15720802
70TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.15610569
71POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.15610569
72OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.15063512
73STAT3_23295773_ChIP-Seq_U87_Human1.14045373
74SOX9_26525672_Chip-Seq_HEART_Mouse1.14029611
75GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.13719911
76SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.12249406
77FUS_26573619_Chip-Seq_HEK293_Human1.11834081
78YAP1_20516196_ChIP-Seq_MESCs_Mouse1.11498665
79ZNF217_24962896_ChIP-Seq_MCF-7_Human1.10177625
80* STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.09982820
81VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.09444557
82WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.09056110
83* RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.08832043
84JUN_21703547_ChIP-Seq_K562_Human1.07911052
85NANOG_18555785_Chip-Seq_ESCs_Mouse1.05790819
86EWS_26573619_Chip-Seq_HEK293_Human1.05730701
87TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.05301974
88DNAJC2_21179169_ChIP-ChIP_NT2_Human1.05087193
89WT1_25993318_ChIP-Seq_PODOCYTE_Human1.04725536
90TP53_18474530_ChIP-ChIP_U2OS_Human1.04211220
91TCF4_23295773_ChIP-Seq_U87_Human1.02754263
92PRDM14_20953172_ChIP-Seq_ESCs_Human1.02554649
93* TP53_20018659_ChIP-ChIP_R1E_Mouse1.00033098
94* TRIM28_17542650_ChIP-ChIP_NTERA2_Human0.98983227
95SMAD3_21741376_ChIP-Seq_HESCs_Human0.96887441
96NR3C1_21868756_ChIP-Seq_MCF10A_Human0.96724534
97RUNX2_22187159_ChIP-Seq_PCA_Human0.95957240
98KDM2B_26808549_Chip-Seq_K562_Human0.95903344
99BCAT_22108803_ChIP-Seq_LS180_Human0.95250859
100TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.95212195
101CDX2_19796622_ChIP-Seq_MESCs_Mouse0.95137864
102* POU5F1_18347094_ChIP-ChIP_MESCs_Mouse0.94366398
103ER_23166858_ChIP-Seq_MCF-7_Human0.94157468
104NR3C1_23031785_ChIP-Seq_PC12_Mouse0.93304102
105P53_22127205_ChIP-Seq_FIBROBLAST_Human0.93102012
106MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.92446830
107POU3F2_20337985_ChIP-ChIP_501MEL_Human0.92430229
108AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.92414456
109GATA1_26923725_Chip-Seq_HPCs_Mouse0.91423570
110CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.91171800
111UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.91067564
112KDM2B_26808549_Chip-Seq_REH_Human0.90801515
113MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.90569031
114VDR_22108803_ChIP-Seq_LS180_Human0.90508182
115* CTCF_27219007_Chip-Seq_Bcells_Human0.88670065
116FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.88573445
117TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.88130364
118SMAD4_21741376_ChIP-Seq_HESCs_Human0.87919619
119* ZFP281_18757296_ChIP-ChIP_E14_Mouse0.86217846
120CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.84756514
121RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.83927727

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity6.78479555
2MP0003880_abnormal_central_pattern5.07701268
3MP0003635_abnormal_synaptic_transmissio4.29290119
4MP0009745_abnormal_behavioral_response3.58266424
5MP0002063_abnormal_learning/memory/cond3.58162610
6MP0004270_analgesia3.16837627
7MP0005423_abnormal_somatic_nervous2.96352896
8MP0002064_seizures2.96131925
9MP0002572_abnormal_emotion/affect_behav2.78624781
10MP0002735_abnormal_chemical_nociception2.74916782
11MP0000778_abnormal_nervous_system2.65386008
12MP0001968_abnormal_touch/_nociception2.65125455
13MP0001440_abnormal_grooming_behavior2.53617941
14MP0009046_muscle_twitch2.36777867
15MP0002736_abnormal_nociception_after2.26981185
16MP0001486_abnormal_startle_reflex2.26689545
17MP0002272_abnormal_nervous_system2.19888622
18MP0002734_abnormal_mechanical_nocicepti2.15740983
19MP0001501_abnormal_sleep_pattern2.15716665
20MP0002184_abnormal_innervation2.10848456
21MP0003329_amyloid_beta_deposits2.04450520
22MP0002733_abnormal_thermal_nociception2.02619041
23MP0003136_yellow_coat_color1.95434864
24MP0002067_abnormal_sensory_capabilities1.93659022
25MP0001970_abnormal_pain_threshold1.90831312
26MP0004858_abnormal_nervous_system1.86258677
27MP0006276_abnormal_autonomic_nervous1.85253575
28MP0000569_abnormal_digit_pigmentation1.83791787
29MP0002557_abnormal_social/conspecific_i1.78899512
30MP0004885_abnormal_endolymph1.64907353
31MP0004811_abnormal_neuron_physiology1.63896333
32MP0000955_abnormal_spinal_cord1.61079262
33MP0008569_lethality_at_weaning1.56181514
34MP0002882_abnormal_neuron_morphology1.55037730
35MP0003879_abnormal_hair_cell1.51470903
36MP0003121_genomic_imprinting1.48708476
37MP0000566_synostosis1.46714767
38MP0004142_abnormal_muscle_tone1.46531669
39MP0005171_absent_coat_pigmentation1.42337461
40MP0008961_abnormal_basal_metabolism1.37155733
41MP0002066_abnormal_motor_capabilities/c1.35749064
42MP0005386_behavior/neurological_phenoty1.32671699
43MP0004924_abnormal_behavior1.32671699
44MP0002152_abnormal_brain_morphology1.32146699
45MP0009780_abnormal_chondrocyte_physiolo1.28239570
46MP0001502_abnormal_circadian_rhythm1.26474968
47MP0001905_abnormal_dopamine_level1.26421500
48MP0000049_abnormal_middle_ear1.22866557
49MP0003787_abnormal_imprinting1.22535739
50MP0002909_abnormal_adrenal_gland1.22462875
51MP0003938_abnormal_ear_development1.21715434
52MP0000751_myopathy1.20572932
53MP0001188_hyperpigmentation1.14911777
54MP0003122_maternal_imprinting1.14247916
55MP0003890_abnormal_embryonic-extraembry1.13454194
56MP0005187_abnormal_penis_morphology1.12646390
57MP0005645_abnormal_hypothalamus_physiol1.11815792
58MP0001984_abnormal_olfaction1.11676139
59MP0001177_atelectasis1.10167111
60MP0000537_abnormal_urethra_morphology1.09640593
61MP0002653_abnormal_ependyma_morphology1.07948371
62MP0001529_abnormal_vocalization1.05358667
63MP0003861_abnormal_nervous_system1.02115524
64MP0005248_abnormal_Harderian_gland1.01932543
65MP0002822_catalepsy1.01742008
66MP0004133_heterotaxia0.99936486
67MP0009379_abnormal_foot_pigmentation0.96390077
68MP0002752_abnormal_somatic_nervous0.94886105
69MP0003631_nervous_system_phenotype0.94658488
70MP0000026_abnormal_inner_ear0.93629769
71MP0002938_white_spotting0.93409932
72MP0003633_abnormal_nervous_system0.92710981
73MP0001963_abnormal_hearing_physiology0.91324214
74MP0003632_abnormal_nervous_system0.88573118
75MP0002069_abnormal_eating/drinking_beha0.87952397
76MP0001485_abnormal_pinna_reflex0.87646890
77MP0003878_abnormal_ear_physiology0.86110554
78MP0005377_hearing/vestibular/ear_phenot0.86110554
79MP0002233_abnormal_nose_morphology0.85998533
80MP0002751_abnormal_autonomic_nervous0.85140333
81MP0000604_amyloidosis0.84809166
82MP0006292_abnormal_olfactory_placode0.84494357
83MP0003634_abnormal_glial_cell0.83836459
84MP0003137_abnormal_impulse_conducting0.83727044
85MP0005646_abnormal_pituitary_gland0.83250476
86MP0005551_abnormal_eye_electrophysiolog0.82151745
87MP0002081_perinatal_lethality0.80453491
88MP0003937_abnormal_limbs/digits/tail_de0.78888362
89MP0004085_abnormal_heartbeat0.77660526
90MP0002638_abnormal_pupillary_reflex0.76780726
91MP0000631_abnormal_neuroendocrine_gland0.76061673
92MP0003942_abnormal_urinary_system0.75503313
93MP0001299_abnormal_eye_distance/0.75501927
94MP0001346_abnormal_lacrimal_gland0.74867162
95MP0002102_abnormal_ear_morphology0.74625136
96MP0003385_abnormal_body_wall0.72776688
97MP0002229_neurodegeneration0.72623081
98MP0005394_taste/olfaction_phenotype0.71791508
99MP0005499_abnormal_olfactory_system0.71791508
100MP0003690_abnormal_glial_cell0.71725894
101MP0002876_abnormal_thyroid_physiology0.70607313
102MP0002116_abnormal_craniofacial_bone0.70005782
103MP0005253_abnormal_eye_physiology0.69942631
104MP0004742_abnormal_vestibular_system0.68631444
105MP0001664_abnormal_digestion0.67977162
106MP0004145_abnormal_muscle_electrophysio0.67736135
107MP0002234_abnormal_pharynx_morphology0.65441789
108MP0003283_abnormal_digestive_organ0.64462467
109MP0001348_abnormal_lacrimal_gland0.63628379
110MP0004233_abnormal_muscle_weight0.63510831
111MP0002090_abnormal_vision0.63199489
112MP0003075_altered_response_to0.62181760
113MP0006072_abnormal_retinal_apoptosis0.61962818
114MP0003119_abnormal_digestive_system0.61709961
115MP0010769_abnormal_survival0.60832938
116MP0000462_abnormal_digestive_system0.59828920
117MP0010770_preweaning_lethality0.58461057
118MP0002082_postnatal_lethality0.58461057
119MP0010768_mortality/aging0.57644076

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)6.74177788
2Myokymia (HP:0002411)5.51229736
3Progressive cerebellar ataxia (HP:0002073)5.04825188
4Visual hallucinations (HP:0002367)4.86837352
5Focal seizures (HP:0007359)4.80352105
6Decreased circulating renin level (HP:0003351)4.45789739
7Genetic anticipation (HP:0003743)4.44678277
8Epileptic encephalopathy (HP:0200134)4.27127583
9Atonic seizures (HP:0010819)4.09748534
10Increased circulating renin level (HP:0000848)4.08963562
11Hyperactive renin-angiotensin system (HP:0000841)3.55546597
12Absence seizures (HP:0002121)3.51382409
13Febrile seizures (HP:0002373)3.50550752
14Dialeptic seizures (HP:0011146)3.50047249
15Abnormality of the lower motor neuron (HP:0002366)3.35184158
16Congenital sensorineural hearing impairment (HP:0008527)3.32555979
17Supranuclear gaze palsy (HP:0000605)3.29618577
18Scanning speech (HP:0002168)3.26223890
19Generalized tonic-clonic seizures (HP:0002069)3.20551036
20Hyperventilation (HP:0002883)3.10604535
21Amblyopia (HP:0000646)3.10446442
22Excessive salivation (HP:0003781)3.05950848
23Drooling (HP:0002307)3.05950848
24Broad-based gait (HP:0002136)3.00428567
25Cortical dysplasia (HP:0002539)2.98605647
26Dysmetria (HP:0001310)2.92970486
27Mutism (HP:0002300)2.92783192
28Ulnar claw (HP:0001178)2.92734436
29Epileptiform EEG discharges (HP:0011182)2.86761247
30Aqueductal stenosis (HP:0002410)2.76917730
31Retinal dysplasia (HP:0007973)2.75318594
32Cerebral inclusion bodies (HP:0100314)2.70413332
33Toxemia of pregnancy (HP:0100603)2.66869439
34Oligodactyly (HP:0012165)2.64836743
35Abnormality of the labia minora (HP:0012880)2.61300916
36Heterochromia iridis (HP:0001100)2.59882598
37Impaired smooth pursuit (HP:0007772)2.58094558
38Gaze-evoked nystagmus (HP:0000640)2.57562529
39Dysdiadochokinesis (HP:0002075)2.55100845
40Split foot (HP:0001839)2.54206259
41Protruding tongue (HP:0010808)2.53984982
42Ankle clonus (HP:0011448)2.52649760
43Absent speech (HP:0001344)2.52558944
44Hemiparesis (HP:0001269)2.52460161
45Poor eye contact (HP:0000817)2.48909309
46Bronchomalacia (HP:0002780)2.47849845
47Hyperkalemia (HP:0002153)2.47376707
48Hyperaldosteronism (HP:0000859)2.46707393
49Abnormal eating behavior (HP:0100738)2.45608658
50Truncal ataxia (HP:0002078)2.45507796
51Neurofibrillary tangles (HP:0002185)2.44865347
52Cutaneous finger syndactyly (HP:0010554)2.44832479
53Limb dystonia (HP:0002451)2.43542268
54Urinary bladder sphincter dysfunction (HP:0002839)2.42615618
55Pheochromocytoma (HP:0002666)2.41164128
56Megalencephaly (HP:0001355)2.41132809
57Supernumerary bones of the axial skeleton (HP:0009144)2.40159447
58Action tremor (HP:0002345)2.40056480
59Impaired vibration sensation in the lower limbs (HP:0002166)2.39649400
60Abnormal social behavior (HP:0012433)2.39133450
61Impaired social interactions (HP:0000735)2.39133450
62Diplopia (HP:0000651)2.38476654
63Abnormality of binocular vision (HP:0011514)2.38476654
64Peripheral hypomyelination (HP:0007182)2.37408913
65Sleep apnea (HP:0010535)2.35744751
66Specific learning disability (HP:0001328)2.34209095
67Turricephaly (HP:0000262)2.33839659
68Blue irides (HP:0000635)2.31592752
69Hepatoblastoma (HP:0002884)2.30989020
70Supernumerary ribs (HP:0005815)2.30405024
71Postural instability (HP:0002172)2.29998208
72Anosmia (HP:0000458)2.29283044
73Hemiplegia (HP:0002301)2.29214393
74Stereotypic behavior (HP:0000733)2.28229682
75Poor suck (HP:0002033)2.26619375
76Anxiety (HP:0000739)2.22698568
77Gait imbalance (HP:0002141)2.22445870
78EEG with generalized epileptiform discharges (HP:0011198)2.22443145
79Cutaneous syndactyly (HP:0012725)2.21420294
80Generalized myoclonic seizures (HP:0002123)2.21296723
81Progressive inability to walk (HP:0002505)2.20896503
82Depression (HP:0000716)2.19634569
83Aplasia involving bones of the upper limbs (HP:0009823)2.16880222
84Aplasia of the phalanges of the hand (HP:0009802)2.16880222
85Aplasia involving bones of the extremities (HP:0009825)2.16880222
86Abnormality of the diencephalon (HP:0010662)2.15386978
87Inability to walk (HP:0002540)2.13442131
88Decreased number of large peripheral myelinated nerve fibers (HP:0003387)2.13067838
89Synostosis involving the elbow (HP:0003938)2.12441138
90Humeroradial synostosis (HP:0003041)2.12441138
91Neuroendocrine neoplasm (HP:0100634)2.12142313
92Abnormality of renin-angiotensin system (HP:0000847)2.11168143
93Hypsarrhythmia (HP:0002521)2.10147272
94Urinary urgency (HP:0000012)2.10109357
95Papilledema (HP:0001085)2.08721049
96Hypoplasia of the brainstem (HP:0002365)2.06563387
97Aplasia/Hypoplasia of the brainstem (HP:0007362)2.06563387
98Agitation (HP:0000713)2.06520300
99Polyphagia (HP:0002591)2.05777890
100Optic nerve hypoplasia (HP:0000609)2.03954771
101Abnormality of sodium homeostasis (HP:0010931)2.03262711
102Methylmalonic acidemia (HP:0002912)2.02694487
103Gonadotropin excess (HP:0000837)2.01494048
104Spastic gait (HP:0002064)2.00472461
105Choroideremia (HP:0001139)2.00113621
106Amyotrophic lateral sclerosis (HP:0007354)1.99787259
107Abnormality of salivation (HP:0100755)1.99745630
108Abnormality of ocular smooth pursuit (HP:0000617)1.98075739
109Lower limb amyotrophy (HP:0007210)1.97312863
110Morphological abnormality of the middle ear (HP:0008609)1.95755969
111Narrow nasal bridge (HP:0000446)1.93882889
112Inappropriate behavior (HP:0000719)1.92571447
113Dyskinesia (HP:0100660)1.91849650
114Septo-optic dysplasia (HP:0100842)1.90543992
115Torticollis (HP:0000473)1.90512574
116Ankyloglossia (HP:0010296)1.88925668
117Lissencephaly (HP:0001339)1.88880735
118Incomplete penetrance (HP:0003829)1.88764429
119Ventricular fibrillation (HP:0001663)1.87803005
120Confusion (HP:0001289)1.87726704
121Truncus arteriosus (HP:0001660)1.86803025
122Oligodactyly (hands) (HP:0001180)1.86378021
123Pachygyria (HP:0001302)1.85976686
124Aplasia/Hypoplasia of the pubic bone (HP:0009104)1.83861927
125Enlarged penis (HP:0000040)1.83222312
126Buphthalmos (HP:0000557)1.81722913
127Coronal craniosynostosis (HP:0004440)1.80890532
128Hammertoe (HP:0001765)1.80873436
129Obstructive sleep apnea (HP:0002870)1.80683854
130Tracheomalacia (HP:0002779)1.80299789
131Vertebral arch anomaly (HP:0008438)1.79470019
132Upper limb muscle weakness (HP:0003484)1.78701296
133Autism (HP:0000717)1.77489978
134Short 4th metacarpal (HP:0010044)1.77168615
135Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.77168615
136Termporal pattern (HP:0011008)1.77161810
137Tented upper lip vermilion (HP:0010804)1.76169892
138Neonatal short-limb short stature (HP:0008921)1.73569315
139Aplasia/Hypoplasia of the sternum (HP:0006714)1.72735478
140Myelomeningocele (HP:0002475)1.71879781
141Abnormality of the corticospinal tract (HP:0002492)1.71365802
142Congenital primary aphakia (HP:0007707)1.70586812
143Esotropia (HP:0000565)1.69515090
144Partial duplication of thumb phalanx (HP:0009944)1.69060256
145Abnormality of the 4th metacarpal (HP:0010012)1.67190273
146Medial flaring of the eyebrow (HP:0010747)1.67008114
147Broad foot (HP:0001769)1.65917078
148Myotonia (HP:0002486)1.65013245
149Meningocele (HP:0002435)1.64951016
150Morphological abnormality of the pyramidal tract (HP:0002062)1.64408219
151Lower limb asymmetry (HP:0100559)1.63475250
152Focal dystonia (HP:0004373)1.63241122
153Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.63068641
154Decreased number of peripheral myelinated nerve fibers (HP:0003380)1.62595996
155True hermaphroditism (HP:0010459)1.62452960
156Absent septum pellucidum (HP:0001331)1.61172265

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NTRK35.04045888
2EPHA44.77304677
3MARK14.33205991
4NTRK23.14676227
5MAP3K92.85657824
6TRIM282.75502024
7MARK22.71185975
8TNIK2.58543486
9PLK22.40593323
10MINK12.38820659
11KSR12.28222330
12MAP3K42.14930192
13MAP2K72.13631690
14CSNK1G22.10892594
15MAPK132.00988686
16RPS6KA41.85389032
17CASK1.68192951
18SIK21.53486348
19NTRK11.52555071
20CAMK2B1.47233348
21PAK61.44608982
22CDK51.42532082
23DAPK21.41386193
24UHMK11.39365137
25LATS21.39221811
26FES1.38676140
27PNCK1.35283828
28MAPK151.33625579
29PRKCG1.31367567
30KSR21.26646730
31MKNK21.25901246
32CAMK2A1.22090751
33MAP3K121.17604895
34PHKG11.17593276
35PHKG21.17593276
36MAP2K41.17224986
37DAPK11.15252844
38GRK51.12697025
39CDK31.11297016
40DYRK1A1.11296711
41CAMK11.11292611
42SCYL20.98872046
43CDK180.97859390
44CDK150.94306122
45ADRBK20.90558209
46PRKD30.90365693
47CDK140.89911992
48CSNK1G10.89702136
49DMPK0.89147466
50BCKDK0.86348996
51WEE10.84791310
52TYRO30.84249234
53CDK11A0.82977899
54STK380.82712891
55PRKCE0.80018776
56SGK2230.79832467
57SGK4940.79832467
58MAP3K20.77429369
59SGK10.76386669
60ERBB20.76384202
61PRPF4B0.74664475
62BMX0.74219359
63EPHA30.72738393
64TSSK60.71760070
65CAMKK10.70210582
66EPHB20.67749223
67FGR0.66121135
68PAK30.65624279
69MAP3K70.62681489
70BCR0.62369610
71MAP3K130.61638619
72PRKAA20.61260196
73FER0.61245916
74ERBB30.60853182
75STK110.60417946
76SIK30.59410769
77ICK0.57969436
78PRKCZ0.56904242
79RAF10.54030451
80RIPK40.53959794
81DYRK20.53898117
82DYRK1B0.53643112
83PKN10.52876358
84FYN0.52347103
85CDK190.52334421
86MUSK0.51329257
87FGFR20.51038339
88MAP2K60.49711212
89CAMK2D0.48479281
90CSNK1G30.48447930
91TAOK20.48170827
92NEK60.47626473
93OXSR10.47235129
94PTK2B0.47221080
95PRKCI0.46805983
96ALK0.46772228
97DYRK30.45669964
98FGFR10.45286136
99CAMK2G0.45105192
100RPS6KA30.44811763
101CAMK1G0.44801507
102CSNK1A1L0.44531376
103SGK20.44494036
104MAP3K60.43610713
105ROCK20.43061807
106MOS0.42149604
107CDC42BPA0.41055918
108WNK30.40925833
109CSNK1A10.40830124
110RET0.40354733
111PRKACB0.39457724
112YES10.39275698
113CAMK40.38142448
114RPS6KA50.37767563
115CSNK1E0.36983488
116PRKG20.36773194
117CSNK1D0.36686969
118BRAF0.36126437
119WNK40.34364927
120MKNK10.34333382
121MAP3K100.34255849
122PRKG10.33489024
123PINK10.33460324
124ARAF0.33171540
125PRKCA0.32641547
126PRKACA0.32455391
127MAPK80.32400025
128MAP4K20.31481254
129STK38L0.30917351
130ROCK10.27364025
131MAPK90.26834636
132MAPK100.25687245
133STK390.25363776

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050334.69097141
2Circadian entrainment_Homo sapiens_hsa047133.16073925
3Synaptic vesicle cycle_Homo sapiens_hsa047213.01137193
4Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.99961614
5Glutamatergic synapse_Homo sapiens_hsa047242.94424690
6GABAergic synapse_Homo sapiens_hsa047272.93517275
7Morphine addiction_Homo sapiens_hsa050322.75457835
8Long-term potentiation_Homo sapiens_hsa047202.69524821
9Amphetamine addiction_Homo sapiens_hsa050312.55274331
10Olfactory transduction_Homo sapiens_hsa047402.53282337
11Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.22327554
12Salivary secretion_Homo sapiens_hsa049702.16800024
13Dopaminergic synapse_Homo sapiens_hsa047282.16079747
14Cholinergic synapse_Homo sapiens_hsa047251.90092712
15Taste transduction_Homo sapiens_hsa047421.86633500
16Cocaine addiction_Homo sapiens_hsa050301.86055122
17Axon guidance_Homo sapiens_hsa043601.83192660
18Insulin secretion_Homo sapiens_hsa049111.82206509
19Aldosterone synthesis and secretion_Homo sapiens_hsa049251.79236116
20Long-term depression_Homo sapiens_hsa047301.74672383
21Serotonergic synapse_Homo sapiens_hsa047261.72338382
22Calcium signaling pathway_Homo sapiens_hsa040201.71580076
23Gastric acid secretion_Homo sapiens_hsa049711.69940013
24Oxytocin signaling pathway_Homo sapiens_hsa049211.69358204
25Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.61918025
26Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.53743849
27Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.46750067
28Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.44193959
29cAMP signaling pathway_Homo sapiens_hsa040241.43376550
30Renin secretion_Homo sapiens_hsa049241.40330937
31Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.37436322
32GnRH signaling pathway_Homo sapiens_hsa049121.32153134
33Gap junction_Homo sapiens_hsa045401.23983079
34Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.19189026
35Melanogenesis_Homo sapiens_hsa049161.16619322
36Collecting duct acid secretion_Homo sapiens_hsa049661.16521839
37Steroid biosynthesis_Homo sapiens_hsa001001.13242166
38Estrogen signaling pathway_Homo sapiens_hsa049151.10234683
39Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.09549487
40Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.07785778
41Sulfur relay system_Homo sapiens_hsa041221.02739686
42Parkinsons disease_Homo sapiens_hsa050121.02558272
43Type II diabetes mellitus_Homo sapiens_hsa049301.01663280
44Vibrio cholerae infection_Homo sapiens_hsa051101.00814345
45Ether lipid metabolism_Homo sapiens_hsa005650.99884988
46cGMP-PKG signaling pathway_Homo sapiens_hsa040220.98703116
47Vascular smooth muscle contraction_Homo sapiens_hsa042700.97179496
48Glioma_Homo sapiens_hsa052140.97129608
49Cardiac muscle contraction_Homo sapiens_hsa042600.94549283
50Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.93788064
51Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.88463523
52Phosphatidylinositol signaling system_Homo sapiens_hsa040700.86243869
53ErbB signaling pathway_Homo sapiens_hsa040120.85939607
54Dilated cardiomyopathy_Homo sapiens_hsa054140.83091449
55Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.82789063
56Folate biosynthesis_Homo sapiens_hsa007900.81786019
57Oocyte meiosis_Homo sapiens_hsa041140.80412107
58Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.79542239
59Nitrogen metabolism_Homo sapiens_hsa009100.79261966
60Notch signaling pathway_Homo sapiens_hsa043300.79060313
61Oxidative phosphorylation_Homo sapiens_hsa001900.77187064
62Phospholipase D signaling pathway_Homo sapiens_hsa040720.76252743
63Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.75695403
64Phototransduction_Homo sapiens_hsa047440.74641595
65Dorso-ventral axis formation_Homo sapiens_hsa043200.74500927
66Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.72833304
67Thyroid hormone synthesis_Homo sapiens_hsa049180.71160872
68Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.68425733
69Pancreatic secretion_Homo sapiens_hsa049720.67614033
70Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.66077410
71Wnt signaling pathway_Homo sapiens_hsa043100.65893541
72Rap1 signaling pathway_Homo sapiens_hsa040150.65521007
73MAPK signaling pathway_Homo sapiens_hsa040100.63894119
74Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.61793805
75Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.61415148
76Choline metabolism in cancer_Homo sapiens_hsa052310.61272059
77Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.60746462
78Ras signaling pathway_Homo sapiens_hsa040140.59408008
79Huntingtons disease_Homo sapiens_hsa050160.57970297
80Alcoholism_Homo sapiens_hsa050340.56168079
81Ovarian steroidogenesis_Homo sapiens_hsa049130.55186849
82Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.54022567
83Type I diabetes mellitus_Homo sapiens_hsa049400.53819206
84Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.52495259
85Bile secretion_Homo sapiens_hsa049760.52400927
86Neurotrophin signaling pathway_Homo sapiens_hsa047220.51130972
87Primary bile acid biosynthesis_Homo sapiens_hsa001200.47401307
88Tight junction_Homo sapiens_hsa045300.46904864
89Circadian rhythm_Homo sapiens_hsa047100.46598500
90Inositol phosphate metabolism_Homo sapiens_hsa005620.45170981
91Prion diseases_Homo sapiens_hsa050200.42366342
92Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.42351263
93Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.41691735
94Regulation of actin cytoskeleton_Homo sapiens_hsa048100.41065049
95Maturity onset diabetes of the young_Homo sapiens_hsa049500.40966508
96Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.40716872
97Adherens junction_Homo sapiens_hsa045200.40308738
98Protein export_Homo sapiens_hsa030600.39086256
99Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.38599217
100Alzheimers disease_Homo sapiens_hsa050100.36377667
101Propanoate metabolism_Homo sapiens_hsa006400.36027078
102Glucagon signaling pathway_Homo sapiens_hsa049220.35595413
103Sphingolipid signaling pathway_Homo sapiens_hsa040710.35101907
104VEGF signaling pathway_Homo sapiens_hsa043700.34907569
105Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.34129987
106Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.33397625
107Basal transcription factors_Homo sapiens_hsa030220.30984815
108Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.30910237
109Vitamin B6 metabolism_Homo sapiens_hsa007500.30549982
110Carbohydrate digestion and absorption_Homo sapiens_hsa049730.30316210
111Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.30250828
112Thyroid hormone signaling pathway_Homo sapiens_hsa049190.29857971
113Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.29607927
114Renal cell carcinoma_Homo sapiens_hsa052110.29325020
115Butanoate metabolism_Homo sapiens_hsa006500.28196859
116Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.26411187
117Endocytosis_Homo sapiens_hsa041440.26213577
118Melanoma_Homo sapiens_hsa052180.22858682
119Hedgehog signaling pathway_Homo sapiens_hsa043400.22043127
120Endometrial cancer_Homo sapiens_hsa052130.20046402
121Longevity regulating pathway - mammal_Homo sapiens_hsa042110.19154455
122Basal cell carcinoma_Homo sapiens_hsa052170.18666343
123Colorectal cancer_Homo sapiens_hsa052100.18637830
124Hippo signaling pathway_Homo sapiens_hsa043900.17147062

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