PCDHA1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1synaptic vesicle exocytosis (GO:0016079)6.04582656
2pyrimidine nucleobase catabolic process (GO:0006208)5.84419070
3glutamate secretion (GO:0014047)5.82902263
4positive regulation of calcium ion-dependent exocytosis (GO:0045956)5.75402738
5synaptic vesicle maturation (GO:0016188)5.71652187
6vocalization behavior (GO:0071625)5.65825757
7regulation of short-term neuronal synaptic plasticity (GO:0048172)5.50667540
8synaptic vesicle docking involved in exocytosis (GO:0016081)5.41880585
9regulation of synaptic vesicle exocytosis (GO:2000300)5.19325884
10locomotory exploration behavior (GO:0035641)5.14431215
11protein localization to synapse (GO:0035418)5.07515169
12regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act5.01799324
13neuron cell-cell adhesion (GO:0007158)5.00376958
14layer formation in cerebral cortex (GO:0021819)5.00004053
15positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.96569591
16nucleobase catabolic process (GO:0046113)4.79605778
17regulation of glutamate receptor signaling pathway (GO:1900449)4.64159812
18substrate-independent telencephalic tangential interneuron migration (GO:0021843)4.63569003
19substrate-independent telencephalic tangential migration (GO:0021826)4.63569003
20neurotransmitter secretion (GO:0007269)4.58040947
21exploration behavior (GO:0035640)4.51832639
22gamma-aminobutyric acid transport (GO:0015812)4.45208430
23proline transport (GO:0015824)4.41820642
24cell migration in hindbrain (GO:0021535)4.36359958
25regulation of synaptic vesicle transport (GO:1902803)4.34084563
26neurofilament cytoskeleton organization (GO:0060052)4.23552769
27regulation of synapse structural plasticity (GO:0051823)4.22401490
28postsynaptic membrane organization (GO:0001941)4.17501373
29neuronal action potential propagation (GO:0019227)4.15353259
30regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.90718355
31activation of protein kinase A activity (GO:0034199)3.90233466
32neurotransmitter-gated ion channel clustering (GO:0072578)3.87110998
33dendrite morphogenesis (GO:0048813)3.84415837
34neuron recognition (GO:0008038)3.83960945
35dendritic spine morphogenesis (GO:0060997)3.78673161
36negative regulation of synaptic transmission, GABAergic (GO:0032229)3.78401189
37neuron-neuron synaptic transmission (GO:0007270)3.76425760
38regulation of long-term neuronal synaptic plasticity (GO:0048169)3.75735904
39ionotropic glutamate receptor signaling pathway (GO:0035235)3.75486123
40neuronal ion channel clustering (GO:0045161)3.71149416
41axon ensheathment in central nervous system (GO:0032291)3.68347110
42central nervous system myelination (GO:0022010)3.68347110
43adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)3.67802921
44membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.64218676
45positive regulation of synapse maturation (GO:0090129)3.62980207
46synaptic transmission, glutamatergic (GO:0035249)3.61319865
47regulation of neuronal synaptic plasticity (GO:0048168)3.59558597
48establishment of mitochondrion localization (GO:0051654)3.58650777
49gamma-aminobutyric acid signaling pathway (GO:0007214)3.54307994
50regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.53465582
51positive regulation of membrane potential (GO:0045838)3.49385929
52neurotransmitter transport (GO:0006836)3.49133835
53neuromuscular process controlling posture (GO:0050884)3.48607996
54positive regulation of potassium ion transmembrane transport (GO:1901381)3.47097030
55presynaptic membrane assembly (GO:0097105)3.47062752
56establishment of protein localization to mitochondrial membrane (GO:0090151)3.46998682
57establishment of mitochondrion localization, microtubule-mediated (GO:0034643)3.44455444
58mitochondrion transport along microtubule (GO:0047497)3.44455444
59glutamate receptor signaling pathway (GO:0007215)3.39211729
60clathrin coat assembly (GO:0048268)3.37320796
61response to auditory stimulus (GO:0010996)3.34416531
62axonal fasciculation (GO:0007413)3.32864103
63regulation of neurotransmitter secretion (GO:0046928)3.32539828
64negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.32236002
65regulation of potassium ion transmembrane transport (GO:1901379)3.32045735
66transmission of nerve impulse (GO:0019226)3.29582156
67long-term synaptic potentiation (GO:0060291)3.29530390
68regulation of potassium ion transmembrane transporter activity (GO:1901016)3.28832744
69mechanosensory behavior (GO:0007638)3.28356671
70organelle transport along microtubule (GO:0072384)3.27886090
71negative regulation of microtubule polymerization (GO:0031115)3.27316220
72adult walking behavior (GO:0007628)3.26750624
73synapse assembly (GO:0007416)3.25622175
74membrane repolarization (GO:0086009)3.25294444
75regulation of neurotransmitter levels (GO:0001505)3.23657961
76regulation of excitatory postsynaptic membrane potential (GO:0060079)3.23126103
77presynaptic membrane organization (GO:0097090)3.19927127
78regulation of cAMP-dependent protein kinase activity (GO:2000479)3.19879514
79regulation of postsynaptic membrane potential (GO:0060078)3.19412740
80axon extension (GO:0048675)3.19017394
81cerebral cortex radially oriented cell migration (GO:0021799)3.18670456
82regulation of dendritic spine morphogenesis (GO:0061001)3.16469835
83response to histamine (GO:0034776)3.16469459
84regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)3.16460935
85regulation of vesicle fusion (GO:0031338)3.16356639
86axon cargo transport (GO:0008088)3.15902086
87regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.15327716
88regulation of membrane repolarization (GO:0060306)3.14849855
89central nervous system projection neuron axonogenesis (GO:0021952)3.13150340
90synaptic vesicle endocytosis (GO:0048488)3.13034439
91negative regulation of axon extension (GO:0030517)3.10167459
92regulation of synaptic plasticity (GO:0048167)3.09466953
93response to pheromone (GO:0019236)3.08886387
94startle response (GO:0001964)3.06664401
95retinal ganglion cell axon guidance (GO:0031290)3.05864765
96auditory behavior (GO:0031223)3.05637818
97cerebellar Purkinje cell differentiation (GO:0021702)3.05465323
98behavioral response to cocaine (GO:0048148)3.03590269
99synaptic vesicle transport (GO:0048489)3.02921579
100establishment of synaptic vesicle localization (GO:0097480)3.02921579
101potassium ion homeostasis (GO:0055075)3.01765211
102regulation of neurotransmitter transport (GO:0051588)3.01297814
103membrane repolarization during cardiac muscle cell action potential (GO:0086013)2.98941846
104vesicle transport along microtubule (GO:0047496)2.97182578
105long-term memory (GO:0007616)2.96602648
106transferrin transport (GO:0033572)2.95981442
107membrane repolarization during action potential (GO:0086011)2.95803671
108calcium ion-dependent exocytosis (GO:0017156)2.95757306
109positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.95284506
110potassium ion import (GO:0010107)2.95201038
111sodium ion export (GO:0071436)2.94517750
112synapse organization (GO:0050808)2.92925719
113regulation of potassium ion transport (GO:0043266)2.92664615
114establishment of vesicle localization (GO:0051650)2.92649098
115negative regulation of cytosolic calcium ion concentration (GO:0051481)2.92580715
116positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.91624688
117ATP hydrolysis coupled proton transport (GO:0015991)2.91475158
118energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)2.91475158
119neuromuscular process controlling balance (GO:0050885)2.90067565
120positive regulation of axon extension (GO:0045773)2.89888111
121membrane depolarization during action potential (GO:0086010)2.89202743
122negative regulation of axonogenesis (GO:0050771)2.87930359
123positive regulation of synaptic transmission, glutamatergic (GO:0051968)2.86254670
124negative regulation of potassium ion transmembrane transporter activity (GO:1901017)2.85930833
125neuromuscular process (GO:0050905)2.85847623
126neuron projection extension (GO:1990138)2.85540669
127innervation (GO:0060384)2.85423505
128regulation of calcium ion-dependent exocytosis (GO:0017158)2.84491454
129membrane hyperpolarization (GO:0060081)2.84108077
130cellular potassium ion homeostasis (GO:0030007)2.83307406
131synaptic transmission (GO:0007268)2.83053912
132positive regulation of synapse assembly (GO:0051965)2.82839390
133prepulse inhibition (GO:0060134)2.82666335
134positive regulation of potassium ion transport (GO:0043268)2.80982216
135cell differentiation in hindbrain (GO:0021533)2.80928170
136negative regulation of oligodendrocyte differentiation (GO:0048715)2.80522531
137behavioral response to nicotine (GO:0035095)2.79821925
138negative regulation of neurotransmitter secretion (GO:0046929)2.69842596
139parturition (GO:0007567)2.65324996
140head development (GO:0060322)2.63114883
141regulation of synaptic transmission, glutamatergic (GO:0051966)2.63056528

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.44714742
2GBX2_23144817_ChIP-Seq_PC3_Human4.10951040
3SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.08935802
4REST_21632747_ChIP-Seq_MESCs_Mouse2.96962746
5SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.93407109
6GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.92460992
7* JARID2_20064375_ChIP-Seq_MESCs_Mouse2.91511715
8NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.87642160
9ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.76892806
10EZH2_27304074_Chip-Seq_ESCs_Mouse2.51241700
11JARID2_20075857_ChIP-Seq_MESCs_Mouse2.49889343
12* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.49448036
13EZH2_18974828_ChIP-Seq_MESCs_Mouse2.44165546
14RNF2_18974828_ChIP-Seq_MESCs_Mouse2.44165546
15* REST_18959480_ChIP-ChIP_MESCs_Mouse2.43933789
16SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.43448797
17* MTF2_20144788_ChIP-Seq_MESCs_Mouse2.42815263
18AR_21572438_ChIP-Seq_LNCaP_Human2.36390337
19RARB_27405468_Chip-Seq_BRAIN_Mouse2.33795361
20SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.31230037
21DROSHA_22980978_ChIP-Seq_HELA_Human2.30772115
22CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.29113049
23* EZH2_27294783_Chip-Seq_ESCs_Mouse2.24732315
24SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.23703264
25* SUZ12_27294783_Chip-Seq_ESCs_Mouse2.18919834
26CTBP2_25329375_ChIP-Seq_LNCAP_Human2.14454233
27RNF2_27304074_Chip-Seq_ESCs_Mouse2.09091995
28TAF15_26573619_Chip-Seq_HEK293_Human2.02879981
29CTBP1_25329375_ChIP-Seq_LNCAP_Human1.90147987
30EED_16625203_ChIP-ChIP_MESCs_Mouse1.88625746
31MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.86907252
32IKZF1_21737484_ChIP-ChIP_HCT116_Human1.76496811
33HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.73499894
34ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.70775489
35* ZFP57_27257070_Chip-Seq_ESCs_Mouse1.69887611
36* SMAD4_21799915_ChIP-Seq_A2780_Human1.67599248
37* ERG_21242973_ChIP-ChIP_JURKAT_Human1.65301297
38TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.65119477
39EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.62667966
40ZNF274_21170338_ChIP-Seq_K562_Hela1.60239199
41* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.56923767
42PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.54057563
43VDR_22108803_ChIP-Seq_LS180_Human1.52480988
44SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.49143396
45IGF1R_20145208_ChIP-Seq_DFB_Human1.48335270
46NR3C1_23031785_ChIP-Seq_PC12_Mouse1.48162969
47SOX2_21211035_ChIP-Seq_LN229_Gbm1.47836341
48P300_19829295_ChIP-Seq_ESCs_Human1.46395726
49TOP2B_26459242_ChIP-Seq_MCF-7_Human1.37230004
50AR_25329375_ChIP-Seq_VCAP_Human1.35649119
51KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.34046566
52SMAD3_21741376_ChIP-Seq_EPCs_Human1.33839329
53CBX2_27304074_Chip-Seq_ESCs_Mouse1.31592727
54OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.31346202
55RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.30697038
56RNF2_27304074_Chip-Seq_NSC_Mouse1.28111337
57TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.26266796
58SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.25145827
59BMI1_23680149_ChIP-Seq_NPCS_Mouse1.24759860
60PIAS1_25552417_ChIP-Seq_VCAP_Human1.24552190
61* RING1B_27294783_Chip-Seq_ESCs_Mouse1.23527756
62STAT3_23295773_ChIP-Seq_U87_Human1.22700339
63TP53_20018659_ChIP-ChIP_R1E_Mouse1.21500334
64CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.21458957
65TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.20294822
66POU3F2_20337985_ChIP-ChIP_501MEL_Human1.19198790
67AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.17571480
68AR_19668381_ChIP-Seq_PC3_Human1.14773559
69YAP1_20516196_ChIP-Seq_MESCs_Mouse1.13711662
70MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.13119865
71ARNT_22903824_ChIP-Seq_MCF-7_Human1.13068882
72FUS_26573619_Chip-Seq_HEK293_Human1.12496567
73FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.12402793
74CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.12266216
75DNAJC2_21179169_ChIP-ChIP_NT2_Human1.11997877
76GATA1_26923725_Chip-Seq_HPCs_Mouse1.11207928
77TCF4_23295773_ChIP-Seq_U87_Human1.11016677
78* MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.09966199
79AHR_22903824_ChIP-Seq_MCF-7_Human1.09865593
80RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.09511447
81ZFP281_18757296_ChIP-ChIP_E14_Mouse1.08257575
82PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.07296413
83ZNF217_24962896_ChIP-Seq_MCF-7_Human1.04839674
84TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.04623209
85JUN_21703547_ChIP-Seq_K562_Human1.04370748
86RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.04323354
87P53_22127205_ChIP-Seq_FIBROBLAST_Human1.03732029
88WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.03313504
89RUNX2_22187159_ChIP-Seq_PCA_Human1.01081194
90RING1B_27294783_Chip-Seq_NPCs_Mouse1.00012156
91WT1_25993318_ChIP-Seq_PODOCYTE_Human0.97702897
92STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse0.97387842
93CDX2_19796622_ChIP-Seq_MESCs_Mouse0.96915687
94OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.96021221
95PRDM14_20953172_ChIP-Seq_ESCs_Human0.95696464
96NANOG_18555785_Chip-Seq_ESCs_Mouse0.95003333
97LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.94529602
98TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.94167643
99POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.94167643
100UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.93364552
101RBPJ_22232070_ChIP-Seq_NCS_Mouse0.93235476
102TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.93160645
103SMAD3_21741376_ChIP-Seq_ESCs_Human0.92796135
104TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.92738563
105SMAD4_21741376_ChIP-Seq_HESCs_Human0.92609421
106TP53_18474530_ChIP-ChIP_U2OS_Human0.91877749
107TAL1_26923725_Chip-Seq_HPCs_Mouse0.90369277
108KDM2B_26808549_Chip-Seq_K562_Human0.90287969
109TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.89901411
110SMAD4_21741376_ChIP-Seq_EPCs_Human0.89130275
111P53_22387025_ChIP-Seq_ESCs_Mouse0.88590205
112SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.88118199
113STAT6_21828071_ChIP-Seq_BEAS2B_Human0.88046767
114ER_23166858_ChIP-Seq_MCF-7_Human0.87475747
115KDM2B_26808549_Chip-Seq_REH_Human0.87308030
116GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.86661079
117FLI1_21867929_ChIP-Seq_TH2_Mouse0.86565714
118EWS_26573619_Chip-Seq_HEK293_Human0.86540061
119NR3C1_21868756_ChIP-Seq_MCF10A_Human0.86289632
120TRIM28_17542650_ChIP-ChIP_NTERA2_Human0.83908146

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity5.97131829
2MP0004270_analgesia4.58023198
3MP0003635_abnormal_synaptic_transmissio4.06495834
4MP0003880_abnormal_central_pattern3.99578492
5MP0009046_muscle_twitch3.55388547
6MP0002063_abnormal_learning/memory/cond3.31150507
7MP0009780_abnormal_chondrocyte_physiolo3.30475812
8MP0003123_paternal_imprinting3.23579341
9MP0009745_abnormal_behavioral_response3.20181124
10MP0002064_seizures3.14050049
11MP0002734_abnormal_mechanical_nocicepti3.06275397
12MP0001968_abnormal_touch/_nociception3.02437127
13MP0002572_abnormal_emotion/affect_behav2.72246856
14MP0002735_abnormal_chemical_nociception2.63747469
15MP0005423_abnormal_somatic_nervous2.52623705
16MP0001486_abnormal_startle_reflex2.52249736
17MP0008877_abnormal_DNA_methylation2.49812121
18MP0002736_abnormal_nociception_after2.38474656
19MP0002272_abnormal_nervous_system2.37347052
20MP0001440_abnormal_grooming_behavior2.34575255
21MP0003121_genomic_imprinting2.31161946
22MP0002733_abnormal_thermal_nociception2.30076237
23MP0000778_abnormal_nervous_system2.19493506
24MP0003329_amyloid_beta_deposits2.14058133
25MP0002067_abnormal_sensory_capabilities2.04447828
26MP0001970_abnormal_pain_threshold2.03695702
27MP0002184_abnormal_innervation1.99747037
28MP0005386_behavior/neurological_phenoty1.96467608
29MP0004924_abnormal_behavior1.96467608
30MP0002653_abnormal_ependyma_morphology1.94077528
31MP0004811_abnormal_neuron_physiology1.90224502
32MP0002909_abnormal_adrenal_gland1.79880404
33MP0006276_abnormal_autonomic_nervous1.79092749
34MP0002557_abnormal_social/conspecific_i1.78210212
35MP0000955_abnormal_spinal_cord1.78133738
36MP0005646_abnormal_pituitary_gland1.77095507
37MP0001501_abnormal_sleep_pattern1.73124511
38MP0003879_abnormal_hair_cell1.67901183
39MP0004858_abnormal_nervous_system1.65608562
40MP0008569_lethality_at_weaning1.54034087
41MP0001529_abnormal_vocalization1.51068892
42MP0002837_dystrophic_cardiac_calcinosis1.50096093
43MP0002882_abnormal_neuron_morphology1.48748134
44MP0003890_abnormal_embryonic-extraembry1.48603437
45MP0002066_abnormal_motor_capabilities/c1.48510056
46MP0003787_abnormal_imprinting1.45191655
47MP0001984_abnormal_olfaction1.44738282
48MP0000569_abnormal_digit_pigmentation1.41065681
49MP0004142_abnormal_muscle_tone1.39985328
50MP0001348_abnormal_lacrimal_gland1.36279521
51MP0003122_maternal_imprinting1.34658227
52MP0006292_abnormal_olfactory_placode1.27645818
53MP0004885_abnormal_endolymph1.24994921
54MP0002163_abnormal_gland_morphology1.23255452
55MP0004133_heterotaxia1.22635195
56MP0002152_abnormal_brain_morphology1.20165963
57MP0008789_abnormal_olfactory_epithelium1.19436919
58MP0002822_catalepsy1.19184415
59MP0000751_myopathy1.16943000
60MP0001905_abnormal_dopamine_level1.15615667
61MP0004145_abnormal_muscle_electrophysio1.14029331
62MP0005379_endocrine/exocrine_gland_phen1.13137795
63MP0000604_amyloidosis1.12703936
64MP0002928_abnormal_bile_duct1.10658663
65MP0003938_abnormal_ear_development1.09052542
66MP0005248_abnormal_Harderian_gland1.08778336
67MP0004147_increased_porphyrin_level1.06164599
68MP0006072_abnormal_retinal_apoptosis1.01811333
69MP0003633_abnormal_nervous_system1.01670668
70MP0005645_abnormal_hypothalamus_physiol0.99476230
71MP0003631_nervous_system_phenotype0.96223912
72MP0002229_neurodegeneration0.96108257
73MP0002102_abnormal_ear_morphology0.95888889
74MP0000026_abnormal_inner_ear0.94954779
75MP0000631_abnormal_neuroendocrine_gland0.94414581
76MP0000013_abnormal_adipose_tissue0.93215395
77MP0003634_abnormal_glial_cell0.92274884
78MP0002876_abnormal_thyroid_physiology0.89342738
79MP0002069_abnormal_eating/drinking_beha0.88916694
80MP0001485_abnormal_pinna_reflex0.87244517
81MP0001188_hyperpigmentation0.86853146
82MP0002234_abnormal_pharynx_morphology0.85691850
83MP0003011_delayed_dark_adaptation0.85184022
84MP0001963_abnormal_hearing_physiology0.84447482
85MP0003119_abnormal_digestive_system0.83803195
86MP0004085_abnormal_heartbeat0.83505815
87MP0010386_abnormal_urinary_bladder0.82422821
88MP0004130_abnormal_muscle_cell0.81758809
89MP0003632_abnormal_nervous_system0.81158960
90MP0008872_abnormal_physiological_respon0.81114738
91MP0004215_abnormal_myocardial_fiber0.80673393
92MP0004233_abnormal_muscle_weight0.80555697
93MP0001346_abnormal_lacrimal_gland0.80396078
94MP0002752_abnormal_somatic_nervous0.79878374
95MP0001177_atelectasis0.79094838
96MP0003942_abnormal_urinary_system0.78563209
97MP0001502_abnormal_circadian_rhythm0.76999152
98MP0003646_muscle_fatigue0.76474006
99MP0005187_abnormal_penis_morphology0.75125677
100MP0003303_peritoneal_inflammation0.74789878
101MP0003137_abnormal_impulse_conducting0.74249286
102MP0000534_abnormal_ureter_morphology0.74083735
103MP0004484_altered_response_of0.73187932
104MP0009379_abnormal_foot_pigmentation0.72314613
105MP0005623_abnormal_meninges_morphology0.71893299
106MP0005551_abnormal_eye_electrophysiolog0.71572940
107MP0005195_abnormal_posterior_eye0.70660820
108MP0006035_abnormal_mitochondrial_morpho0.69435365
109MP0005394_taste/olfaction_phenotype0.68575314
110MP0005499_abnormal_olfactory_system0.68575314
111MP0008874_decreased_physiological_sensi0.68365787
112MP0005535_abnormal_body_temperature0.66681571
113MP0002090_abnormal_vision0.66497053
114MP0003861_abnormal_nervous_system0.65271813
115MP0004742_abnormal_vestibular_system0.65118605
116MP0005253_abnormal_eye_physiology0.64086405
117MP0001299_abnormal_eye_distance/0.63752196
118MP0002160_abnormal_reproductive_system0.63113845
119MP0001943_abnormal_respiration0.60161687
120MP0001986_abnormal_taste_sensitivity0.59875695
121MP0010770_preweaning_lethality0.59863686
122MP0002082_postnatal_lethality0.59863686
123MP0010769_abnormal_survival0.58499589
124MP0002638_abnormal_pupillary_reflex0.58325378
125MP0003283_abnormal_digestive_organ0.58294474
126MP0003690_abnormal_glial_cell0.57923357
127MP0000920_abnormal_myelination0.55417949
128MP0003956_abnormal_body_size0.55284239
129MP0008961_abnormal_basal_metabolism0.55205307

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)7.62737021
2Myokymia (HP:0002411)6.10114546
3Atonic seizures (HP:0010819)5.42189259
4Epileptic encephalopathy (HP:0200134)5.13999467
5Focal seizures (HP:0007359)5.09762027
6Febrile seizures (HP:0002373)4.98833461
7Visual hallucinations (HP:0002367)4.77006915
8Absence seizures (HP:0002121)4.36721667
9Mutism (HP:0002300)4.20775705
10Pheochromocytoma (HP:0002666)3.87735650
11Supranuclear gaze palsy (HP:0000605)3.75807076
12Dialeptic seizures (HP:0011146)3.71599177
13Generalized tonic-clonic seizures (HP:0002069)3.68693437
14Hyperventilation (HP:0002883)3.64256175
15Neuroendocrine neoplasm (HP:0100634)3.63516278
16Progressive cerebellar ataxia (HP:0002073)3.53703727
17Abnormality of binocular vision (HP:0011514)3.37687550
18Diplopia (HP:0000651)3.37687550
19Abnormal pancreas size (HP:0012094)3.30422753
20Poor eye contact (HP:0000817)3.30160302
21Amyotrophic lateral sclerosis (HP:0007354)3.29893097
22Papilledema (HP:0001085)3.26073720
23Progressive inability to walk (HP:0002505)3.25088809
24Action tremor (HP:0002345)3.23301705
25Polyphagia (HP:0002591)3.23078539
26Limb dystonia (HP:0002451)3.20241661
27Abnormality of the corticospinal tract (HP:0002492)3.18272100
28Impaired social interactions (HP:0000735)3.15835703
29Abnormal social behavior (HP:0012433)3.15835703
30Broad-based gait (HP:0002136)3.11525275
31Abnormal eating behavior (HP:0100738)3.04310168
32Ankle clonus (HP:0011448)3.03244478
33Akinesia (HP:0002304)2.95605028
34Impaired vibration sensation in the lower limbs (HP:0002166)2.91901512
35Cerebral inclusion bodies (HP:0100314)2.82162771
36Insidious onset (HP:0003587)2.80796664
37Termporal pattern (HP:0011008)2.80796664
38Epileptiform EEG discharges (HP:0011182)2.80179934
39Drooling (HP:0002307)2.80166753
40Excessive salivation (HP:0003781)2.80166753
41Neurofibrillary tangles (HP:0002185)2.78188283
42EEG with generalized epileptiform discharges (HP:0011198)2.72724004
43Abnormality of midbrain morphology (HP:0002418)2.71710900
44Molar tooth sign on MRI (HP:0002419)2.71710900
45Sleep apnea (HP:0010535)2.68007824
46Torticollis (HP:0000473)2.67344798
47Thyroid-stimulating hormone excess (HP:0002925)2.67248510
48Urinary bladder sphincter dysfunction (HP:0002839)2.67082143
49Hypsarrhythmia (HP:0002521)2.65975730
50Inability to walk (HP:0002540)2.64909146
51Medial flaring of the eyebrow (HP:0010747)2.63885285
52Depression (HP:0000716)2.63833091
53Anxiety (HP:0000739)2.58364132
54Gait imbalance (HP:0002141)2.51918210
55Gaze-evoked nystagmus (HP:0000640)2.51526634
56Congenital primary aphakia (HP:0007707)2.48783631
57Focal dystonia (HP:0004373)2.48397315
58Dysdiadochokinesis (HP:0002075)2.47880572
59Status epilepticus (HP:0002133)2.46627841
60Inappropriate behavior (HP:0000719)2.45779069
61Fetal akinesia sequence (HP:0001989)2.45700944
62Urinary urgency (HP:0000012)2.45681789
63Generalized myoclonic seizures (HP:0002123)2.44625871
64Truncal ataxia (HP:0002078)2.44396581
65Spastic gait (HP:0002064)2.43415508
66Neoplasm of the peripheral nervous system (HP:0100007)2.43260330
67Absent rod-and cone-mediated responses on ERG (HP:0007688)2.39232226
68Hemiparesis (HP:0001269)2.37929686
69Amblyopia (HP:0000646)2.37845259
70Craniofacial dystonia (HP:0012179)2.36714600
71Nephrogenic diabetes insipidus (HP:0009806)2.35327150
72Genetic anticipation (HP:0003743)2.33631021
73Nephronophthisis (HP:0000090)2.28796510
74Morphological abnormality of the pyramidal tract (HP:0002062)2.25557417
75Agitation (HP:0000713)2.24003749
76Neuronal loss in central nervous system (HP:0002529)2.22428939
77Neoplasm of the adrenal cortex (HP:0100641)2.20964938
78Bradykinesia (HP:0002067)2.18980935
79Dysmetria (HP:0001310)2.18171314
80Abnormality of the lower motor neuron (HP:0002366)2.17133481
81Hemiplegia (HP:0002301)2.14817450
82Anomalous pulmonary venous return (HP:0010772)2.12891801
83Pancreatic fibrosis (HP:0100732)2.12479292
84Osteomalacia (HP:0002749)2.11408735
85Restlessness (HP:0000711)2.10173336
86True hermaphroditism (HP:0010459)2.10092680
87Chronic hepatic failure (HP:0100626)2.09728565
88Hepatoblastoma (HP:0002884)2.08456562
89Intention tremor (HP:0002080)2.07860503
90Vaginal atresia (HP:0000148)2.06597805
91Postural instability (HP:0002172)2.06094152
92Poor suck (HP:0002033)2.05903996
93Progressive microcephaly (HP:0000253)2.05784711
94Genital tract atresia (HP:0001827)2.04861376
95Absent speech (HP:0001344)2.03374210
96Pachygyria (HP:0001302)2.02976389
97Metaphyseal dysplasia (HP:0100255)2.02537890
98Apathy (HP:0000741)2.00991889
99Aqueductal stenosis (HP:0002410)1.99077430
100Impaired smooth pursuit (HP:0007772)1.97542435
101Lissencephaly (HP:0001339)1.96626935
102Lower limb muscle weakness (HP:0007340)1.96266582
103Megalencephaly (HP:0001355)1.95352272
104Stereotypic behavior (HP:0000733)1.94665418
105Failure to thrive in infancy (HP:0001531)1.93846193
106Adrenal hypoplasia (HP:0000835)1.93703729
107Esotropia (HP:0000565)1.93437901
108Impaired vibratory sensation (HP:0002495)1.92490370
109Abnormal rod and cone electroretinograms (HP:0008323)1.90485201
110Specific learning disability (HP:0001328)1.89992495
111Hypomagnesemia (HP:0002917)1.89359817
112Abnormality of pain sensation (HP:0010832)1.87396376
113Impaired pain sensation (HP:0007328)1.87396376
114Spastic tetraplegia (HP:0002510)1.87033275
115Generalized hypotonia (HP:0001290)1.86224686
116Abnormal mitochondria in muscle tissue (HP:0008316)1.85387686
117Aplasia/Hypoplasia of the brainstem (HP:0007362)1.85306354
118Hypoplasia of the brainstem (HP:0002365)1.85306354
119Acute necrotizing encephalopathy (HP:0006965)1.84521042
120Myotonia (HP:0002486)1.82688798
121Cerebral hypomyelination (HP:0006808)1.82138807
122Abnormality of the labia minora (HP:0012880)1.82068830
123Abnormality of the renal medulla (HP:0100957)1.81400702
124Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.80003360
125Degeneration of the lateral corticospinal tracts (HP:0002314)1.80003360
126Hypoventilation (HP:0002791)1.79812772
127Incomplete penetrance (HP:0003829)1.78754230
128Poor coordination (HP:0002370)1.78313514
129Abnormality of the vocal cords (HP:0008777)1.77387514
130Abnormality of the pulmonary veins (HP:0011718)1.75808232
131Delusions (HP:0000746)1.75706466
132Hypoplasia of the corpus callosum (HP:0002079)1.75541399
133Abnormality of salivation (HP:0100755)1.75306615
134Abnormality of magnesium homeostasis (HP:0004921)1.74415070
135Deep palmar crease (HP:0006191)1.71022169
136Oligodactyly (hands) (HP:0001180)1.69844493
137Obstructive sleep apnea (HP:0002870)1.69375659
138Hyperthyroidism (HP:0000836)1.68492241
139Dyskinesia (HP:0100660)1.67560247

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MARK16.79993669
2STK164.56197245
3MAP3K93.94911536
4MAP3K43.47742504
5NTRK33.16107648
6MAP2K73.11917281
7MINK12.78148022
8PINK12.61121414
9CASK2.54921705
10MAP3K122.15074248
11NTRK22.15027417
12MAP2K42.13159891
13PHKG21.98694915
14PHKG11.98694915
15EPHA41.93936589
16DYRK21.85422450
17MAPK131.76511493
18DAPK21.73722444
19LATS21.68899089
20PDK31.58484080
21PDK41.58484080
22NTRK11.58180887
23DAPK11.52049166
24PAK61.50749981
25ERBB31.44745416
26CDK51.41540721
27PLK21.41032889
28CAMKK11.40590742
29ADRBK21.38715274
30CSNK1G21.35082059
31KSR11.27118701
32STK391.25686713
33PRKCG1.24001307
34SCYL21.22263127
35GRK51.19561741
36KSR21.14079595
37DMPK1.13279950
38CDK191.12913766
39CAMKK21.11674155
40NEK11.10053717
41UHMK11.03900465
42SIK20.98574262
43TAF10.97693319
44FRK0.95620964
45PNCK0.95043649
46RET0.94738294
47CDK180.94611482
48MAP3K20.92631697
49CSNK1G30.92505187
50PRKD30.91777076
51CDK140.91248450
52CDK150.90891132
53TAOK10.90154966
54PAK30.87450196
55STK110.83703214
56PDK20.81532491
57MARK20.79879654
58BRAF0.77962128
59CAMK2A0.77802210
60CDK11A0.77195071
61TRIM280.77028384
62CAMK1D0.73889758
63LIMK10.73341693
64DYRK1A0.73270228
65CCNB10.73247108
66PKN10.71872598
67RPS6KA20.68070972
68NME10.67827164
69CSNK1A1L0.66054265
70ALK0.65968421
71FES0.65263216
72MAPK120.65044082
73PRKCE0.63284361
74TYRO30.62536396
75TNIK0.62411063
76SIK30.61795010
77MAP3K60.61206013
78CAMK2B0.61162677
79LMTK20.61053925
80MAP4K20.60630932
81PRKCZ0.58359815
82CAMK2G0.58346409
83CAMK2D0.57464678
84CSNK1E0.56814567
85PRKACA0.56387406
86SGK2230.55822117
87SGK4940.55822117
88PRPF4B0.54396478
89BCR0.53352019
90FYN0.52984637
91OXSR10.51960401
92PIK3CA0.51599078
93PRKCH0.49489646
94ERBB40.48430002
95SGK10.48398289
96SGK30.48352429
97CSNK1G10.45157314
98CSNK1A10.43961901
99MAP2K60.43556204
100WNK30.42239231
101WNK10.42158671
102FGFR20.42035921
103BRSK10.40849948
104GRK10.39506984
105WNK40.38947546
106SGK20.37829027
107PRKCA0.37697910
108PRKG10.37673320
109RIPK40.37262337
110RPS6KA30.36958244
111PDK10.36897509
112PRKCI0.36560762
113CAMK10.35512909
114NEK20.33894664
115AKT30.32528050
116MAPK100.32169518
117CSNK1D0.31682823
118MAP3K10.30972243
119STK380.30652154
120PLK40.30542202
121CAMK1G0.30456741
122CAMK40.30162655
123FER0.30048587
124PRKAA10.29829159
125MAPK90.28912063
126ARAF0.28791067
127PRKCB0.28674290
128MAP2K20.27774529
129PDPK10.26761233
130PRKACG0.26334793

Predicted pathways (KEGG)

RankGene SetZ-score
1Synaptic vesicle cycle_Homo sapiens_hsa047213.86128901
2Nicotine addiction_Homo sapiens_hsa050333.42119719
3GABAergic synapse_Homo sapiens_hsa047272.64262153
4Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.55388223
5Circadian entrainment_Homo sapiens_hsa047132.42827035
6Morphine addiction_Homo sapiens_hsa050322.33086487
7Collecting duct acid secretion_Homo sapiens_hsa049662.32821031
8Olfactory transduction_Homo sapiens_hsa047402.28007696
9Long-term potentiation_Homo sapiens_hsa047202.24809159
10Dopaminergic synapse_Homo sapiens_hsa047282.16793338
11Glutamatergic synapse_Homo sapiens_hsa047242.14367285
12Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.11268296
13Amphetamine addiction_Homo sapiens_hsa050312.06518565
14Insulin secretion_Homo sapiens_hsa049111.85326238
15Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.76604332
16Cholinergic synapse_Homo sapiens_hsa047251.76135628
17Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.75431277
18Vibrio cholerae infection_Homo sapiens_hsa051101.71184226
19Salivary secretion_Homo sapiens_hsa049701.69130309
20Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.64167905
21Taste transduction_Homo sapiens_hsa047421.61267375
22Cocaine addiction_Homo sapiens_hsa050301.55931053
23Oxidative phosphorylation_Homo sapiens_hsa001901.53240402
24Gastric acid secretion_Homo sapiens_hsa049711.49635503
25Renin secretion_Homo sapiens_hsa049241.49284153
26Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.46640708
27Aldosterone synthesis and secretion_Homo sapiens_hsa049251.46257895
28Serotonergic synapse_Homo sapiens_hsa047261.41375702
29Axon guidance_Homo sapiens_hsa043601.38053614
30Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.34942599
31Oxytocin signaling pathway_Homo sapiens_hsa049211.34108647
32Long-term depression_Homo sapiens_hsa047301.31798399
33Alzheimers disease_Homo sapiens_hsa050101.23138258
34Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.22849088
35Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.22796981
36Parkinsons disease_Homo sapiens_hsa050121.22780554
37Gap junction_Homo sapiens_hsa045401.21173929
38GnRH signaling pathway_Homo sapiens_hsa049121.17130374
39Type II diabetes mellitus_Homo sapiens_hsa049301.16284132
40Estrogen signaling pathway_Homo sapiens_hsa049151.13559633
41Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.12655091
42Calcium signaling pathway_Homo sapiens_hsa040201.11451413
43Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.10567211
44Cardiac muscle contraction_Homo sapiens_hsa042601.06374238
45Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.02286159
462-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.95030408
47Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.94426084
48ErbB signaling pathway_Homo sapiens_hsa040120.93687126
49Butanoate metabolism_Homo sapiens_hsa006500.91653149
50Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.90856541
51cAMP signaling pathway_Homo sapiens_hsa040240.90108603
52Pyruvate metabolism_Homo sapiens_hsa006200.88959259
53Glioma_Homo sapiens_hsa052140.88941082
54Melanogenesis_Homo sapiens_hsa049160.87692326
55Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.83743334
56cGMP-PKG signaling pathway_Homo sapiens_hsa040220.81699036
57Oocyte meiosis_Homo sapiens_hsa041140.80768589
58Huntingtons disease_Homo sapiens_hsa050160.79342918
59Glucagon signaling pathway_Homo sapiens_hsa049220.75958638
60Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.74073980
61Phosphatidylinositol signaling system_Homo sapiens_hsa040700.71493676
62Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.70321016
63Phototransduction_Homo sapiens_hsa047440.66142054
64Ether lipid metabolism_Homo sapiens_hsa005650.65169445
65Dorso-ventral axis formation_Homo sapiens_hsa043200.62529816
66Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.62070321
67Hippo signaling pathway_Homo sapiens_hsa043900.61666110
68Type I diabetes mellitus_Homo sapiens_hsa049400.61653171
69Vascular smooth muscle contraction_Homo sapiens_hsa042700.60987838
70Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.59851985
71Fatty acid biosynthesis_Homo sapiens_hsa000610.59820441
72Vitamin B6 metabolism_Homo sapiens_hsa007500.59545415
73Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.59030585
74Endometrial cancer_Homo sapiens_hsa052130.58689261
75Neurotrophin signaling pathway_Homo sapiens_hsa047220.57547660
76Steroid biosynthesis_Homo sapiens_hsa001000.56942638
77Thyroid hormone synthesis_Homo sapiens_hsa049180.56669716
78Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.55745878
79MAPK signaling pathway_Homo sapiens_hsa040100.55623758
80Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.54639636
81Regulation of autophagy_Homo sapiens_hsa041400.53873905
82Phagosome_Homo sapiens_hsa041450.53697816
83Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.53626296
84Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.53108224
85Insulin signaling pathway_Homo sapiens_hsa049100.53101448
86Dilated cardiomyopathy_Homo sapiens_hsa054140.52125301
87Colorectal cancer_Homo sapiens_hsa052100.51463519
88Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.51352439
89Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.50953416
90Alcoholism_Homo sapiens_hsa050340.50703338
91Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.48207093
92Carbohydrate digestion and absorption_Homo sapiens_hsa049730.48067702
93Ras signaling pathway_Homo sapiens_hsa040140.47506999
94Protein export_Homo sapiens_hsa030600.47369890
95alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.45874097
96Renal cell carcinoma_Homo sapiens_hsa052110.44688267
97Bile secretion_Homo sapiens_hsa049760.44667051
98Rheumatoid arthritis_Homo sapiens_hsa053230.44591212
99Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.44190144
100Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.43681138
101Hedgehog signaling pathway_Homo sapiens_hsa043400.41834340
102Phospholipase D signaling pathway_Homo sapiens_hsa040720.41397258
103Peroxisome_Homo sapiens_hsa041460.41324829
104Prion diseases_Homo sapiens_hsa050200.41300441
105Pancreatic secretion_Homo sapiens_hsa049720.41154123
106Linoleic acid metabolism_Homo sapiens_hsa005910.41070501
107VEGF signaling pathway_Homo sapiens_hsa043700.39383679
108Fatty acid metabolism_Homo sapiens_hsa012120.39378681
109Sphingolipid signaling pathway_Homo sapiens_hsa040710.39297134
110Choline metabolism in cancer_Homo sapiens_hsa052310.38235951
111SNARE interactions in vesicular transport_Homo sapiens_hsa041300.37816573
112AMPK signaling pathway_Homo sapiens_hsa041520.37787840
113Thyroid hormone signaling pathway_Homo sapiens_hsa049190.37698478
114Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.37202100
115Wnt signaling pathway_Homo sapiens_hsa043100.36493555
116Nitrogen metabolism_Homo sapiens_hsa009100.35762484
117Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.35652984
118beta-Alanine metabolism_Homo sapiens_hsa004100.33895657
119Rap1 signaling pathway_Homo sapiens_hsa040150.33655130
120Endocytosis_Homo sapiens_hsa041440.33367201
121Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.33153657
122Ovarian steroidogenesis_Homo sapiens_hsa049130.32772137
123Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.30178240
124Basal cell carcinoma_Homo sapiens_hsa052170.27088929

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