Rank | Gene Set | Z-score |
---|---|---|
1 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 5.49564077 |
2 | protein localization to synapse (GO:0035418) | 5.46437933 |
3 | vocalization behavior (GO:0071625) | 5.41736505 |
4 | synaptic vesicle exocytosis (GO:0016079) | 5.38871648 |
5 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 5.34893476 |
6 | neuron cell-cell adhesion (GO:0007158) | 5.20151377 |
7 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 5.13843135 |
8 | synaptic vesicle maturation (GO:0016188) | 5.10982700 |
9 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 5.03521443 |
10 | glutamate secretion (GO:0014047) | 5.02142958 |
11 | regulation of synaptic vesicle exocytosis (GO:2000300) | 4.90750802 |
12 | locomotory exploration behavior (GO:0035641) | 4.85592015 |
13 | layer formation in cerebral cortex (GO:0021819) | 4.78527612 |
14 | pyrimidine nucleobase catabolic process (GO:0006208) | 4.74381017 |
15 | regulation of glutamate receptor signaling pathway (GO:1900449) | 4.70623321 |
16 | proline transport (GO:0015824) | 4.65735680 |
17 | negative regulation of microtubule polymerization (GO:0031115) | 4.41433503 |
18 | exploration behavior (GO:0035640) | 4.40662006 |
19 | synaptic vesicle docking involved in exocytosis (GO:0016081) | 4.33400593 |
20 | neurotransmitter secretion (GO:0007269) | 4.31458361 |
21 | regulation of synaptic vesicle transport (GO:1902803) | 4.22771981 |
22 | nucleobase catabolic process (GO:0046113) | 4.14428828 |
23 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339) | 4.11538730 |
24 | neuron recognition (GO:0008038) | 4.10999763 |
25 | ionotropic glutamate receptor signaling pathway (GO:0035235) | 4.04343825 |
26 | regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310) | 4.03266010 |
27 | regulation of synapse structural plasticity (GO:0051823) | 4.00463037 |
28 | regulation of long-term neuronal synaptic plasticity (GO:0048169) | 3.96793769 |
29 | cell migration in hindbrain (GO:0021535) | 3.95212120 |
30 | glutamate receptor signaling pathway (GO:0007215) | 3.82480594 |
31 | regulation of neuronal synaptic plasticity (GO:0048168) | 3.78289979 |
32 | postsynaptic membrane organization (GO:0001941) | 3.75887834 |
33 | synaptic transmission, glutamatergic (GO:0035249) | 3.72888238 |
34 | dendritic spine morphogenesis (GO:0060997) | 3.70728872 |
35 | positive regulation of synapse maturation (GO:0090129) | 3.69602624 |
36 | dendrite morphogenesis (GO:0048813) | 3.69176589 |
37 | nonmotile primary cilium assembly (GO:0035058) | 3.69118502 |
38 | neuron-neuron synaptic transmission (GO:0007270) | 3.68252112 |
39 | auditory behavior (GO:0031223) | 3.65465054 |
40 | negative regulation of synaptic transmission, GABAergic (GO:0032229) | 3.62203495 |
41 | neurotransmitter-gated ion channel clustering (GO:0072578) | 3.57277926 |
42 | gamma-aminobutyric acid transport (GO:0015812) | 3.55819651 |
43 | regulation of excitatory postsynaptic membrane potential (GO:0060079) | 3.53819410 |
44 | axonal fasciculation (GO:0007413) | 3.51855899 |
45 | positive regulation of potassium ion transmembrane transporter activity (GO:1901018) | 3.51453614 |
46 | neurotransmitter transport (GO:0006836) | 3.48048321 |
47 | positive regulation of membrane potential (GO:0045838) | 3.46685888 |
48 | activation of protein kinase A activity (GO:0034199) | 3.43629224 |
49 | organelle transport along microtubule (GO:0072384) | 3.35693973 |
50 | neuronal action potential propagation (GO:0019227) | 3.34619532 |
51 | establishment of mitochondrion localization (GO:0051654) | 3.33753354 |
52 | regulation of postsynaptic membrane potential (GO:0060078) | 3.33667804 |
53 | regulation of neurotransmitter secretion (GO:0046928) | 3.33250257 |
54 | establishment of mitochondrion localization, microtubule-mediated (GO:0034643) | 3.31495659 |
55 | mitochondrion transport along microtubule (GO:0047497) | 3.31495659 |
56 | synapse assembly (GO:0007416) | 3.29056872 |
57 | presynaptic membrane assembly (GO:0097105) | 3.28827554 |
58 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 3.28702560 |
59 | adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191) | 3.27653573 |
60 | regulation of vesicle fusion (GO:0031338) | 3.21297069 |
61 | synaptic vesicle endocytosis (GO:0048488) | 3.18806328 |
62 | dopamine receptor signaling pathway (GO:0007212) | 3.18650469 |
63 | gamma-aminobutyric acid signaling pathway (GO:0007214) | 3.18386255 |
64 | regulation of neurotransmitter levels (GO:0001505) | 3.16943680 |
65 | innervation (GO:0060384) | 3.14956116 |
66 | regulation of synaptic plasticity (GO:0048167) | 3.14879962 |
67 | regulation of inhibitory postsynaptic membrane potential (GO:0060080) | 3.14622510 |
68 | retinal ganglion cell axon guidance (GO:0031290) | 3.12881578 |
69 | clathrin coat assembly (GO:0048268) | 3.12206438 |
70 | transmission of nerve impulse (GO:0019226) | 3.10889945 |
71 | long-term memory (GO:0007616) | 3.10492963 |
72 | presynaptic membrane organization (GO:0097090) | 3.10259600 |
73 | regulation of dendritic spine morphogenesis (GO:0061001) | 3.10100673 |
74 | vesicle transport along microtubule (GO:0047496) | 3.09318991 |
75 | axon extension (GO:0048675) | 3.08799159 |
76 | * homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156) | 3.08632703 |
77 | cellular potassium ion homeostasis (GO:0030007) | 3.07491881 |
78 | central nervous system projection neuron axonogenesis (GO:0021952) | 3.06173309 |
79 | long-term synaptic potentiation (GO:0060291) | 3.01680796 |
80 | positive regulation of neurotransmitter secretion (GO:0001956) | 3.01391144 |
81 | regulation of neurotransmitter transport (GO:0051588) | 3.00313548 |
82 | membrane depolarization during action potential (GO:0086010) | 2.99469560 |
83 | regulation of synaptic transmission, glutamatergic (GO:0051966) | 2.98544486 |
84 | membrane depolarization (GO:0051899) | 2.98269910 |
85 | positive regulation of neurotransmitter transport (GO:0051590) | 2.97929233 |
86 | regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371) | 2.96793163 |
87 | dendritic spine organization (GO:0097061) | 2.94929794 |
88 | learning (GO:0007612) | 2.94865074 |
89 | regulation of cAMP-dependent protein kinase activity (GO:2000479) | 2.93988517 |
90 | cerebellar granule cell differentiation (GO:0021707) | 2.93981686 |
91 | regulation of glutamate secretion (GO:0014048) | 2.93814753 |
92 | axon cargo transport (GO:0008088) | 2.91455330 |
93 | synapse organization (GO:0050808) | 2.91020078 |
94 | positive regulation of synapse assembly (GO:0051965) | 2.88190815 |
95 | central nervous system neuron axonogenesis (GO:0021955) | 2.87917631 |
96 | response to pheromone (GO:0019236) | 2.87885374 |
97 | mechanosensory behavior (GO:0007638) | 2.87668945 |
98 | positive regulation of synaptic transmission, GABAergic (GO:0032230) | 2.87511502 |
99 | regulation of respiratory gaseous exchange by neurological system process (GO:0002087) | 2.87244850 |
100 | positive regulation of dendritic spine morphogenesis (GO:0061003) | 2.86131756 |
101 | G-protein coupled acetylcholine receptor signaling pathway (GO:0007213) | 2.85331311 |
102 | detection of calcium ion (GO:0005513) | 2.83747747 |
103 | synaptic transmission (GO:0007268) | 2.83685197 |
104 | positive regulation of dendritic spine development (GO:0060999) | 2.82141570 |
105 | behavioral response to ethanol (GO:0048149) | 2.81230825 |
106 | response to histamine (GO:0034776) | 2.80780601 |
107 | neuromuscular process controlling balance (GO:0050885) | 2.80546931 |
108 | establishment of synaptic vesicle localization (GO:0097480) | 2.80496960 |
109 | hippocampus development (GO:0021766) | 2.75236210 |
110 | regulation of synapse maturation (GO:0090128) | 2.72645119 |
111 | regulation of synapse assembly (GO:0051963) | 2.70577559 |
112 | response to auditory stimulus (GO:0010996) | 2.70322929 |
113 | neuronal ion channel clustering (GO:0045161) | 2.65320551 |
114 | forebrain neuron differentiation (GO:0021879) | 2.57308720 |
115 | negative regulation of synaptic transmission, glutamatergic (GO:0051967) | 2.56509640 |
116 | establishment of nucleus localization (GO:0040023) | 2.56042024 |
117 | * cell-cell adhesion (GO:0098609) | 2.49782956 |
118 | * cell-cell adhesion via plasma-membrane adhesion molecules (GO:0098742) | 2.49768968 |
119 | axonogenesis (GO:0007409) | 2.49579870 |
120 | spinal cord development (GO:0021510) | 2.48290487 |
121 | adult walking behavior (GO:0007628) | 2.48133596 |
122 | protein targeting to Golgi (GO:0000042) | 2.46539766 |
123 | cerebral cortex radially oriented cell migration (GO:0021799) | 2.45147971 |
124 | cerebellar Purkinje cell layer development (GO:0021680) | 2.42806633 |
125 | neuronal stem cell maintenance (GO:0097150) | 2.42778579 |
126 | dendrite development (GO:0016358) | 2.41870667 |
127 | inner ear receptor cell development (GO:0060119) | 2.41477077 |
128 | regulation of Arp2/3 complex-mediated actin nucleation (GO:0034315) | 2.39303211 |
129 | establishment of protein localization to Golgi (GO:0072600) | 2.37898437 |
130 | startle response (GO:0001964) | 2.36353223 |
131 | regulation of development, heterochronic (GO:0040034) | 2.36345989 |
132 | cranial nerve morphogenesis (GO:0021602) | 2.36312362 |
133 | regulation of synapse organization (GO:0050807) | 2.35943504 |
134 | neuron projection extension involved in neuron projection guidance (GO:1902284) | 2.35543833 |
135 | axon extension involved in axon guidance (GO:0048846) | 2.35543833 |
136 | ephrin receptor signaling pathway (GO:0048013) | 2.35112981 |
137 | adult behavior (GO:0030534) | 2.34101794 |
138 | neuromuscular synaptic transmission (GO:0007274) | 2.33257397 |
139 | spinal cord motor neuron differentiation (GO:0021522) | 2.32590654 |
140 | behavioral defense response (GO:0002209) | 2.30573820 |
141 | behavioral fear response (GO:0001662) | 2.30573820 |
142 | ectodermal placode formation (GO:0060788) | 2.29081297 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EZH2_22144423_ChIP-Seq_EOC_Human | 6.00296044 |
2 | GBX2_23144817_ChIP-Seq_PC3_Human | 4.03909907 |
3 | * SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 3.17975492 |
4 | * JARID2_20064375_ChIP-Seq_MESCs_Mouse | 3.03007453 |
5 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 2.99322750 |
6 | REST_21632747_ChIP-Seq_MESCs_Mouse | 2.86553416 |
7 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 2.62383825 |
8 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 2.62180627 |
9 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 2.60673931 |
10 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 2.60673931 |
11 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.60462317 |
12 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 2.58030860 |
13 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 2.50736874 |
14 | * SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 2.49205517 |
15 | * SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 2.49181294 |
16 | * MTF2_20144788_ChIP-Seq_MESCs_Mouse | 2.45430268 |
17 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 2.31311193 |
18 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 2.25427901 |
19 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 2.23731081 |
20 | * SUZ12_27294783_Chip-Seq_ESCs_Mouse | 2.18706952 |
21 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 2.16130594 |
22 | * EED_16625203_ChIP-ChIP_MESCs_Mouse | 2.15354208 |
23 | DROSHA_22980978_ChIP-Seq_HELA_Human | 2.12603475 |
24 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.12145990 |
25 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 2.10515453 |
26 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.06154062 |
27 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 2.04993147 |
28 | AR_21572438_ChIP-Seq_LNCaP_Human | 2.04760084 |
29 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 2.02109837 |
30 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.94660909 |
31 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.92752703 |
32 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.90226603 |
33 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.80583607 |
34 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.73237125 |
35 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.70143963 |
36 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.67762494 |
37 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.64803686 |
38 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.63584431 |
39 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.60966208 |
40 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.59924657 |
41 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 1.58577549 |
42 | P300_19829295_ChIP-Seq_ESCs_Human | 1.56895825 |
43 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.56647489 |
44 | * SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.54191754 |
45 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.48170128 |
46 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.47250422 |
47 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.46711563 |
48 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.42959575 |
49 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.42252972 |
50 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.39904564 |
51 | * SOX2_21211035_ChIP-Seq_LN229_Gbm | 1.38627139 |
52 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.36055117 |
53 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.35772394 |
54 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.32832176 |
55 | AR_25329375_ChIP-Seq_VCAP_Human | 1.32105639 |
56 | * RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.29866545 |
57 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.28833156 |
58 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.28819091 |
59 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.24832568 |
60 | * POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.23710038 |
61 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 1.23276977 |
62 | RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 1.21593848 |
63 | STAT3_23295773_ChIP-Seq_U87_Human | 1.20940614 |
64 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.20323663 |
65 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.19427592 |
66 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.16515234 |
67 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 1.16380510 |
68 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.15501917 |
69 | AR_19668381_ChIP-Seq_PC3_Human | 1.15395174 |
70 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.13987837 |
71 | EWS_26573619_Chip-Seq_HEK293_Human | 1.13916272 |
72 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.13723416 |
73 | RING1B_27294783_Chip-Seq_NPCs_Mouse | 1.13447596 |
74 | YAP1_20516196_ChIP-Seq_MESCs_Mouse | 1.12938320 |
75 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 1.12398666 |
76 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.11913811 |
77 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.11661687 |
78 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.11060215 |
79 | STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse | 1.11050776 |
80 | FUS_26573619_Chip-Seq_HEK293_Human | 1.11038447 |
81 | SOX9_26525672_Chip-Seq_HEART_Mouse | 1.10462060 |
82 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.09665707 |
83 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 1.09615612 |
84 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.09413411 |
85 | TCF4_23295773_ChIP-Seq_U87_Human | 1.08487703 |
86 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.07631373 |
87 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.07342009 |
88 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.07342009 |
89 | JUN_21703547_ChIP-Seq_K562_Human | 1.05931331 |
90 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 1.05791981 |
91 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 1.05671967 |
92 | VDR_22108803_ChIP-Seq_LS180_Human | 1.05053291 |
93 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 1.04895082 |
94 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.04715611 |
95 | TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 1.04311758 |
96 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 1.03764780 |
97 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.03522809 |
98 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.03512775 |
99 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.03464306 |
100 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.03438702 |
101 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.03432422 |
102 | MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 1.03038839 |
103 | WT1_25993318_ChIP-Seq_PODOCYTE_Human | 1.03014584 |
104 | LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.02609770 |
105 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 1.01836070 |
106 | TAL1_26923725_Chip-Seq_HPCs_Mouse | 1.01761474 |
107 | SMAD3_21741376_ChIP-Seq_ESCs_Human | 1.01041724 |
108 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 1.00277576 |
109 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 0.99645146 |
110 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.99645146 |
111 | OLIG2_26023283_ChIP-Seq_AINV15_Mouse | 0.99554463 |
112 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.98320794 |
113 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 0.97711623 |
114 | EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 0.96899066 |
115 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 0.95826902 |
116 | ER_23166858_ChIP-Seq_MCF-7_Human | 0.95521893 |
117 | ISL1_27105846_Chip-Seq_CPCs_Mouse | 0.95430778 |
118 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 0.94346424 |
119 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.94178098 |
120 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.93000383 |
121 | SMAD4_21741376_ChIP-Seq_HESCs_Human | 0.91897747 |
122 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.91874258 |
123 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 0.88475733 |
124 | EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 0.87681945 |
125 | TP53_18474530_ChIP-ChIP_U2OS_Human | 0.87669972 |
126 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 0.87307297 |
127 | KDM2B_26808549_Chip-Seq_K562_Human | 0.85655945 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0004859_abnormal_synaptic_plasticity | 5.87534852 |
2 | MP0004270_analgesia | 4.26424042 |
3 | MP0003880_abnormal_central_pattern | 4.21779456 |
4 | MP0003635_abnormal_synaptic_transmissio | 4.04871022 |
5 | MP0001968_abnormal_touch/_nociception | 3.59463116 |
6 | MP0002063_abnormal_learning/memory/cond | 3.30948072 |
7 | MP0009745_abnormal_behavioral_response | 3.22372026 |
8 | MP0002735_abnormal_chemical_nociception | 3.14242716 |
9 | MP0002734_abnormal_mechanical_nocicepti | 3.09993537 |
10 | MP0002064_seizures | 2.85667743 |
11 | MP0002736_abnormal_nociception_after | 2.85489925 |
12 | MP0002572_abnormal_emotion/affect_behav | 2.73847304 |
13 | MP0009046_muscle_twitch | 2.71854614 |
14 | MP0005423_abnormal_somatic_nervous | 2.69444498 |
15 | MP0002733_abnormal_thermal_nociception | 2.55796315 |
16 | MP0002272_abnormal_nervous_system | 2.44126453 |
17 | MP0006276_abnormal_autonomic_nervous | 2.37731624 |
18 | MP0000778_abnormal_nervous_system | 2.36274573 |
19 | MP0002822_catalepsy | 2.36199634 |
20 | MP0001440_abnormal_grooming_behavior | 2.29751819 |
21 | MP0004858_abnormal_nervous_system | 2.27516340 |
22 | MP0001970_abnormal_pain_threshold | 2.25553934 |
23 | MP0002184_abnormal_innervation | 2.24348257 |
24 | MP0003329_amyloid_beta_deposits | 2.20322667 |
25 | MP0001486_abnormal_startle_reflex | 2.19253403 |
26 | MP0001501_abnormal_sleep_pattern | 2.16312759 |
27 | MP0005248_abnormal_Harderian_gland | 2.11719639 |
28 | MP0002067_abnormal_sensory_capabilities | 2.01029350 |
29 | MP0004811_abnormal_neuron_physiology | 1.94521286 |
30 | MP0002653_abnormal_ependyma_morphology | 1.91078733 |
31 | MP0005386_behavior/neurological_phenoty | 1.88098738 |
32 | MP0004924_abnormal_behavior | 1.88098738 |
33 | MP0002557_abnormal_social/conspecific_i | 1.81794226 |
34 | MP0009780_abnormal_chondrocyte_physiolo | 1.81458479 |
35 | MP0001984_abnormal_olfaction | 1.79641870 |
36 | MP0000955_abnormal_spinal_cord | 1.70959606 |
37 | MP0002909_abnormal_adrenal_gland | 1.62128006 |
38 | MP0003119_abnormal_digestive_system | 1.53763327 |
39 | MP0002882_abnormal_neuron_morphology | 1.51739113 |
40 | MP0003890_abnormal_embryonic-extraembry | 1.51695701 |
41 | MP0008569_lethality_at_weaning | 1.51274543 |
42 | MP0004133_heterotaxia | 1.50883131 |
43 | MP0008995_early_reproductive_senescence | 1.50800655 |
44 | MP0002837_dystrophic_cardiac_calcinosis | 1.42110552 |
45 | MP0002066_abnormal_motor_capabilities/c | 1.41893747 |
46 | MP0003787_abnormal_imprinting | 1.41733337 |
47 | MP0003879_abnormal_hair_cell | 1.40925337 |
48 | MP0008877_abnormal_DNA_methylation | 1.39903217 |
49 | MP0001529_abnormal_vocalization | 1.36068927 |
50 | MP0001905_abnormal_dopamine_level | 1.34168744 |
51 | MP0003121_genomic_imprinting | 1.32422578 |
52 | MP0000566_synostosis | 1.24657442 |
53 | MP0002152_abnormal_brain_morphology | 1.19703338 |
54 | MP0003633_abnormal_nervous_system | 1.18424872 |
55 | MP0005645_abnormal_hypothalamus_physiol | 1.18264906 |
56 | MP0003567_abnormal_fetal_cardiomyocyte | 1.17036118 |
57 | MP0004885_abnormal_endolymph | 1.16458831 |
58 | MP0001346_abnormal_lacrimal_gland | 1.15143921 |
59 | MP0005499_abnormal_olfactory_system | 1.14972585 |
60 | MP0005394_taste/olfaction_phenotype | 1.14972585 |
61 | MP0000604_amyloidosis | 1.14367438 |
62 | MP0001188_hyperpigmentation | 1.13437561 |
63 | MP0000751_myopathy | 1.12139846 |
64 | MP0002233_abnormal_nose_morphology | 1.12048656 |
65 | MP0000647_abnormal_sebaceous_gland | 1.11611454 |
66 | MP0003283_abnormal_digestive_organ | 1.10626914 |
67 | MP0000049_abnormal_middle_ear | 1.10439693 |
68 | MP0002234_abnormal_pharynx_morphology | 1.09657390 |
69 | MP0003122_maternal_imprinting | 1.08393499 |
70 | MP0003631_nervous_system_phenotype | 1.07928311 |
71 | MP0003937_abnormal_limbs/digits/tail_de | 1.05662204 |
72 | MP0001502_abnormal_circadian_rhythm | 1.05029389 |
73 | MP0001293_anophthalmia | 1.03654253 |
74 | MP0000026_abnormal_inner_ear | 1.03575377 |
75 | MP0002254_reproductive_system_inflammat | 1.01007081 |
76 | MP0002697_abnormal_eye_size | 1.00777701 |
77 | MP0000537_abnormal_urethra_morphology | 1.00775377 |
78 | MP0005253_abnormal_eye_physiology | 1.00369036 |
79 | MP0001348_abnormal_lacrimal_gland | 1.00368885 |
80 | MP0010386_abnormal_urinary_bladder | 0.99017567 |
81 | MP0003755_abnormal_palate_morphology | 0.96292312 |
82 | MP0008872_abnormal_physiological_respon | 0.95632078 |
83 | MP0002069_abnormal_eating/drinking_beha | 0.95329534 |
84 | MP0002229_neurodegeneration | 0.93969599 |
85 | MP0000569_abnormal_digit_pigmentation | 0.92269717 |
86 | MP0005187_abnormal_penis_morphology | 0.90377531 |
87 | MP0004085_abnormal_heartbeat | 0.90126746 |
88 | MP0003634_abnormal_glial_cell | 0.90100550 |
89 | MP0004142_abnormal_muscle_tone | 0.90006944 |
90 | MP0002752_abnormal_somatic_nervous | 0.88847043 |
91 | MP0008789_abnormal_olfactory_epithelium | 0.87696216 |
92 | MP0002081_perinatal_lethality | 0.84702309 |
93 | MP0000427_abnormal_hair_cycle | 0.84285211 |
94 | MP0005646_abnormal_pituitary_gland | 0.84087701 |
95 | MP0004742_abnormal_vestibular_system | 0.83717823 |
96 | MP0003385_abnormal_body_wall | 0.82356864 |
97 | MP0003632_abnormal_nervous_system | 0.82019584 |
98 | MP0001485_abnormal_pinna_reflex | 0.81588305 |
99 | MP0005551_abnormal_eye_electrophysiolog | 0.79962312 |
100 | MP0002090_abnormal_vision | 0.79595786 |
101 | MP0006292_abnormal_olfactory_placode | 0.78887380 |
102 | MP0010030_abnormal_orbit_morphology | 0.78783166 |
103 | MP0000383_abnormal_hair_follicle | 0.77755963 |
104 | MP0000631_abnormal_neuroendocrine_gland | 0.77162350 |
105 | MP0008874_decreased_physiological_sensi | 0.76872845 |
106 | MP0000579_abnormal_nail_morphology | 0.76264866 |
107 | MP0000428_abnormal_craniofacial_morphol | 0.76188934 |
108 | MP0002116_abnormal_craniofacial_bone | 0.75902019 |
109 | MP0005391_vision/eye_phenotype | 0.75561823 |
110 | MP0003861_abnormal_nervous_system | 0.74062927 |
111 | MP0003011_delayed_dark_adaptation | 0.74003846 |
112 | MP0001286_abnormal_eye_development | 0.73707926 |
113 | MP0005535_abnormal_body_temperature | 0.73039966 |
114 | MP0001963_abnormal_hearing_physiology | 0.72851147 |
115 | MP0002751_abnormal_autonomic_nervous | 0.72298812 |
116 | MP0002638_abnormal_pupillary_reflex | 0.72070927 |
117 | MP0004484_altered_response_of | 0.71742664 |
118 | MP0002876_abnormal_thyroid_physiology | 0.70957219 |
119 | MP0004233_abnormal_muscle_weight | 0.69505216 |
120 | MP0000013_abnormal_adipose_tissue | 0.68806354 |
121 | MP0005623_abnormal_meninges_morphology | 0.67070133 |
122 | MP0004215_abnormal_myocardial_fiber | 0.66289748 |
123 | MP0001177_atelectasis | 0.65314449 |
124 | MP0001299_abnormal_eye_distance/ | 0.64280725 |
125 | MP0009379_abnormal_foot_pigmentation | 0.61276633 |
126 | MP0001943_abnormal_respiration | 0.59007988 |
127 | MP0010234_abnormal_vibrissa_follicle | 0.56327096 |
128 | MP0001664_abnormal_digestion | 0.56236500 |
129 | MP0010770_preweaning_lethality | 0.54935356 |
130 | MP0002082_postnatal_lethality | 0.54935356 |
131 | MP0010769_abnormal_survival | 0.54112737 |
132 | MP0004145_abnormal_muscle_electrophysio | 0.54103894 |
133 | MP0003956_abnormal_body_size | 0.53105352 |
134 | MP0002102_abnormal_ear_morphology | 0.51142280 |
135 | MP0010768_mortality/aging | 0.50754404 |
136 | MP0003137_abnormal_impulse_conducting | 0.50680777 |
137 | MP0006072_abnormal_retinal_apoptosis | 0.50049589 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Myokymia (HP:0002411) | 5.97089102 |
2 | Focal motor seizures (HP:0011153) | 5.89773386 |
3 | Visual hallucinations (HP:0002367) | 5.23770889 |
4 | Focal seizures (HP:0007359) | 5.09546040 |
5 | Epileptic encephalopathy (HP:0200134) | 4.58151474 |
6 | Atonic seizures (HP:0010819) | 4.28243288 |
7 | Mutism (HP:0002300) | 4.07363147 |
8 | Absence seizures (HP:0002121) | 3.99873525 |
9 | Progressive cerebellar ataxia (HP:0002073) | 3.92135809 |
10 | Supranuclear gaze palsy (HP:0000605) | 3.87725703 |
11 | Limb dystonia (HP:0002451) | 3.64853748 |
12 | Febrile seizures (HP:0002373) | 3.60959093 |
13 | Termporal pattern (HP:0011008) | 3.59585540 |
14 | Insidious onset (HP:0003587) | 3.59585540 |
15 | Cerebral inclusion bodies (HP:0100314) | 3.57084472 |
16 | Dialeptic seizures (HP:0011146) | 3.49537575 |
17 | Generalized tonic-clonic seizures (HP:0002069) | 3.49123958 |
18 | Abnormality of the corticospinal tract (HP:0002492) | 3.48805224 |
19 | Papilledema (HP:0001085) | 3.31326253 |
20 | Amblyopia (HP:0000646) | 3.27058867 |
21 | Amyotrophic lateral sclerosis (HP:0007354) | 3.25657006 |
22 | Ankle clonus (HP:0011448) | 3.25280382 |
23 | Neurofibrillary tangles (HP:0002185) | 3.24362577 |
24 | Hyperventilation (HP:0002883) | 3.22915860 |
25 | Congenital primary aphakia (HP:0007707) | 3.20882244 |
26 | Action tremor (HP:0002345) | 3.20338697 |
27 | Drooling (HP:0002307) | 3.18944756 |
28 | Excessive salivation (HP:0003781) | 3.18944756 |
29 | Nephrogenic diabetes insipidus (HP:0009806) | 3.18900346 |
30 | Broad-based gait (HP:0002136) | 3.18824684 |
31 | Poor eye contact (HP:0000817) | 3.14674334 |
32 | Progressive inability to walk (HP:0002505) | 3.09647438 |
33 | Urinary bladder sphincter dysfunction (HP:0002839) | 3.07169505 |
34 | Polyphagia (HP:0002591) | 2.98227514 |
35 | Diplopia (HP:0000651) | 2.96710830 |
36 | Abnormality of binocular vision (HP:0011514) | 2.96710830 |
37 | Medial flaring of the eyebrow (HP:0010747) | 2.96434177 |
38 | Abnormal social behavior (HP:0012433) | 2.94458545 |
39 | Impaired social interactions (HP:0000735) | 2.94458545 |
40 | Pheochromocytoma (HP:0002666) | 2.92322133 |
41 | Truncal ataxia (HP:0002078) | 2.88489086 |
42 | Urinary urgency (HP:0000012) | 2.82776363 |
43 | Impaired vibration sensation in the lower limbs (HP:0002166) | 2.80897092 |
44 | Epileptiform EEG discharges (HP:0011182) | 2.77091773 |
45 | EEG with generalized epileptiform discharges (HP:0011198) | 2.73285089 |
46 | Depression (HP:0000716) | 2.69348830 |
47 | Abnormal eating behavior (HP:0100738) | 2.69152264 |
48 | Torticollis (HP:0000473) | 2.65855324 |
49 | Neuroendocrine neoplasm (HP:0100634) | 2.65267932 |
50 | Anxiety (HP:0000739) | 2.64664795 |
51 | Vaginal atresia (HP:0000148) | 2.63777019 |
52 | Spastic gait (HP:0002064) | 2.62676869 |
53 | Hypsarrhythmia (HP:0002521) | 2.62229097 |
54 | Poor coordination (HP:0002370) | 2.61943210 |
55 | Inappropriate behavior (HP:0000719) | 2.59334930 |
56 | Genital tract atresia (HP:0001827) | 2.58449661 |
57 | Hemiparesis (HP:0001269) | 2.54995768 |
58 | Akinesia (HP:0002304) | 2.54550111 |
59 | Cortical dysplasia (HP:0002539) | 2.54449196 |
60 | Apathy (HP:0000741) | 2.54186012 |
61 | Inability to walk (HP:0002540) | 2.53104864 |
62 | Hepatoblastoma (HP:0002884) | 2.51599586 |
63 | Nuclear cataract (HP:0100018) | 2.50931286 |
64 | Genetic anticipation (HP:0003743) | 2.46819171 |
65 | Focal dystonia (HP:0004373) | 2.44579290 |
66 | Agitation (HP:0000713) | 2.43782022 |
67 | Morphological abnormality of the pyramidal tract (HP:0002062) | 2.43037967 |
68 | Hypoplasia of the brainstem (HP:0002365) | 2.41288858 |
69 | Aplasia/Hypoplasia of the brainstem (HP:0007362) | 2.41288858 |
70 | Dysmetria (HP:0001310) | 2.36484474 |
71 | Intestinal atresia (HP:0011100) | 2.34866522 |
72 | Craniofacial dystonia (HP:0012179) | 2.34687381 |
73 | Lower limb muscle weakness (HP:0007340) | 2.34440610 |
74 | Gaze-evoked nystagmus (HP:0000640) | 2.34071201 |
75 | Abnormality of the lower motor neuron (HP:0002366) | 2.33446240 |
76 | Dysdiadochokinesis (HP:0002075) | 2.31124865 |
77 | Medulloblastoma (HP:0002885) | 2.30980035 |
78 | Nephronophthisis (HP:0000090) | 2.29177553 |
79 | Diminished motivation (HP:0000745) | 2.28991709 |
80 | Gait imbalance (HP:0002141) | 2.25763100 |
81 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 2.23704298 |
82 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 2.23704298 |
83 | Oligodactyly (hands) (HP:0001180) | 2.22095866 |
84 | Fetal akinesia sequence (HP:0001989) | 2.20870149 |
85 | Stereotypic behavior (HP:0000733) | 2.20469664 |
86 | Bradykinesia (HP:0002067) | 2.20385691 |
87 | Double outlet right ventricle (HP:0001719) | 2.19593756 |
88 | Congenital malformation of the right heart (HP:0011723) | 2.19593756 |
89 | Septo-optic dysplasia (HP:0100842) | 2.19263532 |
90 | Delusions (HP:0000746) | 2.15811981 |
91 | Hyperthyroidism (HP:0000836) | 2.15663702 |
92 | Optic nerve hypoplasia (HP:0000609) | 2.12679320 |
93 | Abnormality of salivation (HP:0100755) | 2.11179962 |
94 | Scanning speech (HP:0002168) | 2.11077993 |
95 | Absent speech (HP:0001344) | 2.10991862 |
96 | Megalencephaly (HP:0001355) | 2.10888065 |
97 | Impaired smooth pursuit (HP:0007772) | 2.08887537 |
98 | Postural instability (HP:0002172) | 2.08643713 |
99 | Generalized myoclonic seizures (HP:0002123) | 2.07785953 |
100 | Impaired pain sensation (HP:0007328) | 2.04723096 |
101 | Abnormality of pain sensation (HP:0010832) | 2.04723096 |
102 | Failure to thrive in infancy (HP:0001531) | 2.02413650 |
103 | Decreased number of large peripheral myelinated nerve fibers (HP:0003387) | 2.02161314 |
104 | Broad foot (HP:0001769) | 2.01982507 |
105 | Split foot (HP:0001839) | 2.01659706 |
106 | Lissencephaly (HP:0001339) | 2.00710271 |
107 | Hypoventilation (HP:0002791) | 1.99444066 |
108 | True hermaphroditism (HP:0010459) | 1.97445509 |
109 | Abnormality of the pubic bones (HP:0003172) | 1.97184020 |
110 | Lower limb amyotrophy (HP:0007210) | 1.96823110 |
111 | Thyroid-stimulating hormone excess (HP:0002925) | 1.96434492 |
112 | Postaxial hand polydactyly (HP:0001162) | 1.95222442 |
113 | Aqueductal stenosis (HP:0002410) | 1.94683068 |
114 | Exotropia (HP:0000577) | 1.91895575 |
115 | Oligodactyly (HP:0012165) | 1.91834737 |
116 | Neuronal loss in central nervous system (HP:0002529) | 1.91633729 |
117 | Chronic hepatic failure (HP:0100626) | 1.91410845 |
118 | Hypoplasia of the corpus callosum (HP:0002079) | 1.89794517 |
119 | Neoplasm of the peripheral nervous system (HP:0100007) | 1.89317110 |
120 | Rapidly progressive (HP:0003678) | 1.88635297 |
121 | Abnormality of the labia minora (HP:0012880) | 1.85564755 |
122 | Renal dysplasia (HP:0000110) | 1.85563171 |
123 | Protruding tongue (HP:0010808) | 1.85019508 |
124 | Aplasia/Hypoplasia of the pubic bone (HP:0009104) | 1.84651203 |
125 | Pachygyria (HP:0001302) | 1.84152266 |
126 | Specific learning disability (HP:0001328) | 1.83990385 |
127 | Psychosis (HP:0000709) | 1.82546524 |
128 | Sporadic (HP:0003745) | 1.81587262 |
129 | Blue irides (HP:0000635) | 1.80989510 |
130 | Pancreatic fibrosis (HP:0100732) | 1.80300248 |
131 | Abnormality of the renal medulla (HP:0100957) | 1.79759173 |
132 | Sleep apnea (HP:0010535) | 1.78971387 |
133 | Vitreoretinal degeneration (HP:0000655) | 1.77605401 |
134 | Aplasia/Hypoplasia of the lens (HP:0008063) | 1.74513257 |
135 | Micropenis (HP:0000054) | 1.74197186 |
136 | Decreased lacrimation (HP:0000633) | 1.74080306 |
137 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 1.73379696 |
138 | Abnormality of the aortic arch (HP:0012303) | 1.73273892 |
139 | Decreased testicular size (HP:0008734) | 1.73238985 |
140 | Broad alveolar ridges (HP:0000187) | 1.70699734 |
141 | Papillary thyroid carcinoma (HP:0002895) | 1.70134156 |
142 | Occipital encephalocele (HP:0002085) | 1.69760571 |
143 | Labial hypoplasia (HP:0000066) | 1.68201081 |
144 | Abnormality of the ischium (HP:0003174) | 1.66992830 |
145 | Mixed hearing impairment (HP:0000410) | 1.64937797 |
146 | Spastic tetraplegia (HP:0002510) | 1.63817487 |
147 | Alacrima (HP:0000522) | 1.62251285 |
148 | Abnormality of midbrain morphology (HP:0002418) | 1.59054284 |
149 | Molar tooth sign on MRI (HP:0002419) | 1.59054284 |
150 | Spastic paraplegia (HP:0001258) | 1.58558066 |
151 | Intellectual disability, moderate (HP:0002342) | 1.57599591 |
152 | High anterior hairline (HP:0009890) | 1.57421615 |
153 | Paraplegia (HP:0010550) | 1.56970542 |
154 | Dental crowding (HP:0000678) | 1.56560983 |
155 | Unilateral renal agenesis (HP:0000122) | 1.56060828 |
156 | Postaxial foot polydactyly (HP:0001830) | 1.55926416 |
157 | Hypoplastic ischia (HP:0003175) | 1.54731794 |
158 | Neonatal respiratory distress (HP:0002643) | 1.54299344 |
159 | Chorioretinal coloboma (HP:0000567) | 1.53981103 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MARK1 | 5.78700223 |
2 | MAP3K9 | 3.96040853 |
3 | NTRK3 | 3.58306674 |
4 | MAP3K12 | 3.11984000 |
5 | MAP3K4 | 3.07570499 |
6 | EPHA3 | 3.02687215 |
7 | MINK1 | 2.84130725 |
8 | MAP2K7 | 2.73445487 |
9 | NTRK2 | 2.41748053 |
10 | EPHA4 | 2.26490353 |
11 | CASK | 2.14938725 |
12 | DAPK2 | 2.13672742 |
13 | NTRK1 | 2.06839150 |
14 | MAP2K4 | 2.00868396 |
15 | MAPK13 | 2.00813815 |
16 | PHKG1 | 1.98789013 |
17 | PHKG2 | 1.98789013 |
18 | PNCK | 1.86804258 |
19 | PLK2 | 1.73229358 |
20 | KSR2 | 1.71002603 |
21 | PAK6 | 1.70058273 |
22 | DAPK1 | 1.69320398 |
23 | DYRK2 | 1.62691074 |
24 | GRK5 | 1.62062982 |
25 | KSR1 | 1.59915071 |
26 | LATS2 | 1.54213317 |
27 | STK38L | 1.53744884 |
28 | TRIM28 | 1.53695596 |
29 | DYRK3 | 1.51587247 |
30 | CDK5 | 1.42761726 |
31 | EPHB2 | 1.35781501 |
32 | MAP4K2 | 1.30047443 |
33 | ARAF | 1.29168551 |
34 | CAMKK1 | 1.28945129 |
35 | RIPK4 | 1.25436152 |
36 | TESK1 | 1.24739883 |
37 | NME1 | 1.23704125 |
38 | CSNK1G2 | 1.20312635 |
39 | UHMK1 | 1.16856438 |
40 | MKNK1 | 1.15883472 |
41 | PINK1 | 1.15686093 |
42 | ERBB3 | 1.13813592 |
43 | PRKCG | 1.12285924 |
44 | MAP3K2 | 1.12134805 |
45 | TNIK | 1.11460224 |
46 | MKNK2 | 1.07409439 |
47 | CAMKK2 | 1.06246644 |
48 | EPHB1 | 1.04955221 |
49 | SGK2 | 0.98875000 |
50 | CDK14 | 0.94210048 |
51 | RET | 0.92078994 |
52 | CAMK2A | 0.91663278 |
53 | SIK2 | 0.90391611 |
54 | CDK19 | 0.90390663 |
55 | DYRK1B | 0.88848635 |
56 | CDK18 | 0.88087769 |
57 | CDK15 | 0.85524539 |
58 | BRD4 | 0.82279681 |
59 | LIMK1 | 0.81004672 |
60 | CSNK1G3 | 0.79562002 |
61 | PAK3 | 0.78773090 |
62 | CDK11A | 0.75455410 |
63 | PDK4 | 0.75290792 |
64 | PDK3 | 0.75290792 |
65 | ERBB2 | 0.74741298 |
66 | GRK7 | 0.74610957 |
67 | TAOK1 | 0.72594894 |
68 | PRKCE | 0.72546515 |
69 | MARK2 | 0.71865287 |
70 | PRKD3 | 0.71529754 |
71 | PKN2 | 0.69950299 |
72 | DYRK1A | 0.69839814 |
73 | PRPF4B | 0.69133732 |
74 | STK11 | 0.68709069 |
75 | FES | 0.66792415 |
76 | MAP3K6 | 0.66599070 |
77 | SCYL2 | 0.66073614 |
78 | CAMK2B | 0.65803468 |
79 | INSRR | 0.63811659 |
80 | FGFR2 | 0.63620796 |
81 | SIK3 | 0.63341600 |
82 | PTK2B | 0.62573879 |
83 | SRPK1 | 0.62053439 |
84 | MAPK12 | 0.61821044 |
85 | CSNK1A1L | 0.61186544 |
86 | TYRO3 | 0.60979246 |
87 | TSSK6 | 0.60784615 |
88 | PKN1 | 0.59229331 |
89 | PASK | 0.59039491 |
90 | MET | 0.58282590 |
91 | RAF1 | 0.57956599 |
92 | CAMK1G | 0.57404971 |
93 | RPS6KA2 | 0.55851960 |
94 | FRK | 0.55566526 |
95 | ALK | 0.55308798 |
96 | PRKCZ | 0.55004150 |
97 | STK38 | 0.54593541 |
98 | PDGFRA | 0.54373030 |
99 | ADRBK1 | 0.54168732 |
100 | FGR | 0.54042924 |
101 | NEK1 | 0.53749169 |
102 | FER | 0.52110746 |
103 | NEK6 | 0.50470803 |
104 | SGK3 | 0.49720143 |
105 | WNK3 | 0.49350546 |
106 | SGK494 | 0.48370237 |
107 | SGK223 | 0.48370237 |
108 | CSNK1E | 0.48112348 |
109 | MAP2K6 | 0.48063092 |
110 | CSNK1D | 0.47775811 |
111 | SGK1 | 0.45948355 |
112 | CSNK1A1 | 0.45614983 |
113 | CAMK1 | 0.45465008 |
114 | BCR | 0.44517101 |
115 | MAP2K1 | 0.44316499 |
116 | PRKAA1 | 0.43535781 |
117 | RPS6KA4 | 0.42796966 |
118 | CAMK1D | 0.42664870 |
119 | FYN | 0.42564082 |
120 | AKT3 | 0.42181061 |
121 | MAPK9 | 0.40742885 |
122 | DAPK3 | 0.40435833 |
123 | DDR2 | 0.40243239 |
124 | CSNK1G1 | 0.39581543 |
125 | CAMK4 | 0.39408255 |
126 | PRKACB | 0.39391740 |
127 | RIPK1 | 0.39231946 |
128 | OXSR1 | 0.38746476 |
129 | BCKDK | 0.38161347 |
130 | PRKCH | 0.37356284 |
131 | CCNB1 | 0.37033065 |
132 | LMTK2 | 0.35066003 |
133 | BMPR1B | 0.34302279 |
134 | MAP3K13 | 0.33684391 |
135 | RPS6KA3 | 0.32333329 |
136 | CAMK2D | 0.30716772 |
137 | PRKCB | 0.29444841 |
138 | PDK1 | 0.28687998 |
139 | MAP3K1 | 0.27067769 |
140 | ROCK2 | 0.26210788 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 3.51579142 |
2 | Nicotine addiction_Homo sapiens_hsa05033 | 3.46713605 |
3 | Olfactory transduction_Homo sapiens_hsa04740 | 2.68202005 |
4 | Long-term potentiation_Homo sapiens_hsa04720 | 2.54643209 |
5 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 2.53949177 |
6 | Circadian entrainment_Homo sapiens_hsa04713 | 2.53865959 |
7 | GABAergic synapse_Homo sapiens_hsa04727 | 2.49784347 |
8 | Dopaminergic synapse_Homo sapiens_hsa04728 | 2.26484051 |
9 | Glutamatergic synapse_Homo sapiens_hsa04724 | 2.26001835 |
10 | Morphine addiction_Homo sapiens_hsa05032 | 2.25345926 |
11 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 2.19962255 |
12 | Amphetamine addiction_Homo sapiens_hsa05031 | 2.16259651 |
13 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 2.07001800 |
14 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.93999569 |
15 | Salivary secretion_Homo sapiens_hsa04970 | 1.93665491 |
16 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 1.87947733 |
17 | Renin secretion_Homo sapiens_hsa04924 | 1.84968612 |
18 | Insulin secretion_Homo sapiens_hsa04911 | 1.76251186 |
19 | Taste transduction_Homo sapiens_hsa04742 | 1.72414224 |
20 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.71463916 |
21 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.70377906 |
22 | Gastric acid secretion_Homo sapiens_hsa04971 | 1.68798882 |
23 | Long-term depression_Homo sapiens_hsa04730 | 1.68592335 |
24 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.61252319 |
25 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.56100939 |
26 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 1.51802001 |
27 | Protein export_Homo sapiens_hsa03060 | 1.50903956 |
28 | Hippo signaling pathway_Homo sapiens_hsa04390 | 1.42545970 |
29 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 1.41596613 |
30 | Gap junction_Homo sapiens_hsa04540 | 1.41198076 |
31 | GnRH signaling pathway_Homo sapiens_hsa04912 | 1.40629842 |
32 | Axon guidance_Homo sapiens_hsa04360 | 1.39980572 |
33 | Cocaine addiction_Homo sapiens_hsa05030 | 1.38143005 |
34 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.37113556 |
35 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 1.33219709 |
36 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.32938518 |
37 | Basal cell carcinoma_Homo sapiens_hsa05217 | 1.32616569 |
38 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 1.30264418 |
39 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.25916643 |
40 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 1.20251716 |
41 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 1.19893955 |
42 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.17542149 |
43 | Glioma_Homo sapiens_hsa05214 | 1.16783698 |
44 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.16103054 |
45 | Basal transcription factors_Homo sapiens_hsa03022 | 1.13237607 |
46 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 1.13043917 |
47 | Alzheimers disease_Homo sapiens_hsa05010 | 1.11616097 |
48 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 1.11531796 |
49 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 1.10563373 |
50 | Phototransduction_Homo sapiens_hsa04744 | 1.08878623 |
51 | cAMP signaling pathway_Homo sapiens_hsa04024 | 1.04482174 |
52 | Melanogenesis_Homo sapiens_hsa04916 | 1.03276158 |
53 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 1.03070031 |
54 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.02948631 |
55 | ErbB signaling pathway_Homo sapiens_hsa04012 | 1.02038888 |
56 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 1.00364633 |
57 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.99130689 |
58 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.96703553 |
59 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.94129909 |
60 | Parkinsons disease_Homo sapiens_hsa05012 | 0.93916258 |
61 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.93432492 |
62 | Circadian rhythm_Homo sapiens_hsa04710 | 0.92990097 |
63 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.92903485 |
64 | Tight junction_Homo sapiens_hsa04530 | 0.90195147 |
65 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.90028425 |
66 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.89271090 |
67 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.88818186 |
68 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.86753511 |
69 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.86696011 |
70 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.83498018 |
71 | Lysine degradation_Homo sapiens_hsa00310 | 0.82408327 |
72 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.80845660 |
73 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.77961742 |
74 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.70861092 |
75 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.70710569 |
76 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.69157377 |
77 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.68859112 |
78 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.68454732 |
79 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.68391623 |
80 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.67685316 |
81 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.67663616 |
82 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.67269906 |
83 | Endometrial cancer_Homo sapiens_hsa05213 | 0.66302368 |
84 | Alcoholism_Homo sapiens_hsa05034 | 0.65590105 |
85 | Huntingtons disease_Homo sapiens_hsa05016 | 0.64884485 |
86 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.64046231 |
87 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.62222728 |
88 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.61713639 |
89 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.61113974 |
90 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.59972372 |
91 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.59578807 |
92 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.59092491 |
93 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.58815671 |
94 | Prion diseases_Homo sapiens_hsa05020 | 0.58315592 |
95 | Colorectal cancer_Homo sapiens_hsa05210 | 0.57263738 |
96 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.57214862 |
97 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.56577023 |
98 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.55107964 |
99 | Adherens junction_Homo sapiens_hsa04520 | 0.54839619 |
100 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.54350246 |
101 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.53265529 |
102 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.53200851 |
103 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.52680113 |
104 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.52356530 |
105 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.51437484 |
106 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.50647950 |
107 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.50362939 |
108 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.49759021 |
109 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.48833304 |
110 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.47605775 |
111 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.46355859 |
112 | Phagosome_Homo sapiens_hsa04145 | 0.45566614 |
113 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.45494857 |
114 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.45449838 |
115 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.44810106 |
116 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.43989587 |
117 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.42805371 |
118 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.42009683 |
119 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.41557871 |
120 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.38493044 |
121 | ABC transporters_Homo sapiens_hsa02010 | 0.37058112 |
122 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.36421168 |
123 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.36380394 |
124 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.35901074 |
125 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.35770229 |
126 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.35692791 |
127 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.35405342 |
128 | Bile secretion_Homo sapiens_hsa04976 | 0.35037918 |
129 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.34521500 |
130 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.34496564 |
131 | Endocytosis_Homo sapiens_hsa04144 | 0.34259691 |
132 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.32297243 |
133 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.30676021 |
134 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.29076215 |