Rank | Gene Set | Z-score |
---|---|---|
1 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 5.84280889 |
2 | pyrimidine nucleobase catabolic process (GO:0006208) | 5.80529865 |
3 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 5.80038420 |
4 | vocalization behavior (GO:0071625) | 5.78364035 |
5 | neuron cell-cell adhesion (GO:0007158) | 5.53316853 |
6 | protein localization to synapse (GO:0035418) | 5.36404440 |
7 | synaptic vesicle exocytosis (GO:0016079) | 5.34253424 |
8 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 5.32495219 |
9 | synaptic vesicle maturation (GO:0016188) | 5.27948798 |
10 | regulation of glutamate receptor signaling pathway (GO:1900449) | 5.10957038 |
11 | auditory behavior (GO:0031223) | 4.93905649 |
12 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 4.93468866 |
13 | locomotory exploration behavior (GO:0035641) | 4.91746383 |
14 | neurotransmitter-gated ion channel clustering (GO:0072578) | 4.83804784 |
15 | nucleobase catabolic process (GO:0046113) | 4.82064311 |
16 | glutamate secretion (GO:0014047) | 4.75515780 |
17 | regulation of synaptic vesicle exocytosis (GO:2000300) | 4.75127699 |
18 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339) | 4.66706954 |
19 | layer formation in cerebral cortex (GO:0021819) | 4.65997460 |
20 | synaptic vesicle docking involved in exocytosis (GO:0016081) | 4.53186754 |
21 | regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310) | 4.48795064 |
22 | response to auditory stimulus (GO:0010996) | 4.37660783 |
23 | positive regulation of mitochondrial fission (GO:0090141) | 4.36634913 |
24 | postsynaptic membrane organization (GO:0001941) | 4.34662680 |
25 | exploration behavior (GO:0035640) | 4.31788448 |
26 | ionotropic glutamate receptor signaling pathway (GO:0035235) | 4.29077422 |
27 | cell migration in hindbrain (GO:0021535) | 4.25870714 |
28 | regulation of synaptic vesicle transport (GO:1902803) | 4.22109345 |
29 | neurotransmitter secretion (GO:0007269) | 4.18703187 |
30 | positive regulation of synapse maturation (GO:0090129) | 4.14733017 |
31 | mechanosensory behavior (GO:0007638) | 4.02742736 |
32 | presynaptic membrane assembly (GO:0097105) | 4.02241335 |
33 | synaptic transmission, glutamatergic (GO:0035249) | 3.98327113 |
34 | regulation of synapse structural plasticity (GO:0051823) | 3.97632077 |
35 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 3.92871897 |
36 | neuron recognition (GO:0008038) | 3.89489077 |
37 | dendritic spine morphogenesis (GO:0060997) | 3.89478107 |
38 | regulation of neuronal synaptic plasticity (GO:0048168) | 3.87720053 |
39 | regulation of long-term neuronal synaptic plasticity (GO:0048169) | 3.86427335 |
40 | positive regulation of synaptic transmission, dopaminergic (GO:0032226) | 3.78475739 |
41 | neuron-neuron synaptic transmission (GO:0007270) | 3.77179791 |
42 | glutamate receptor signaling pathway (GO:0007215) | 3.74453416 |
43 | proline transport (GO:0015824) | 3.74146687 |
44 | mitochondrial outer membrane permeabilization involved in programmed cell death (GO:1902686) | 3.72222472 |
45 | positive regulation of mitochondrial membrane permeability involved in apoptotic process (GO:1902110 | 3.72222472 |
46 | dendrite morphogenesis (GO:0048813) | 3.70382314 |
47 | regulation of inhibitory postsynaptic membrane potential (GO:0060080) | 3.68733747 |
48 | presynaptic membrane organization (GO:0097090) | 3.65601134 |
49 | retinal ganglion cell axon guidance (GO:0031290) | 3.63005278 |
50 | axonal fasciculation (GO:0007413) | 3.62814231 |
51 | righting reflex (GO:0060013) | 3.59643505 |
52 | regulation of excitatory postsynaptic membrane potential (GO:0060079) | 3.59525674 |
53 | positive regulation of membrane potential (GO:0045838) | 3.58874106 |
54 | negative regulation of microtubule polymerization (GO:0031115) | 3.53727759 |
55 | gamma-aminobutyric acid transport (GO:0015812) | 3.52386400 |
56 | nonmotile primary cilium assembly (GO:0035058) | 3.51581100 |
57 | central nervous system projection neuron axonogenesis (GO:0021952) | 3.50707939 |
58 | neuronal action potential propagation (GO:0019227) | 3.49124389 |
59 | regulation of postsynaptic membrane potential (GO:0060078) | 3.46681279 |
60 | positive regulation of potassium ion transmembrane transporter activity (GO:1901018) | 3.38841281 |
61 | neurotransmitter transport (GO:0006836) | 3.37762462 |
62 | positive regulation of synaptic transmission, glutamatergic (GO:0051968) | 3.36027348 |
63 | long-term memory (GO:0007616) | 3.34888197 |
64 | synapse assembly (GO:0007416) | 3.32161818 |
65 | C4-dicarboxylate transport (GO:0015740) | 3.30747344 |
66 | regulation of dendritic spine morphogenesis (GO:0061001) | 3.30201330 |
67 | positive regulation of dendritic spine morphogenesis (GO:0061003) | 3.29317523 |
68 | activation of protein kinase A activity (GO:0034199) | 3.28116917 |
69 | * homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156) | 3.27734083 |
70 | gamma-aminobutyric acid signaling pathway (GO:0007214) | 3.21347264 |
71 | regulation of respiratory gaseous exchange by neurological system process (GO:0002087) | 3.20000285 |
72 | cerebellar Purkinje cell differentiation (GO:0021702) | 3.19686674 |
73 | regulation of synaptic transmission, glutamatergic (GO:0051966) | 3.19588644 |
74 | behavioral response to nicotine (GO:0035095) | 3.19347036 |
75 | positive regulation of synaptic transmission, GABAergic (GO:0032230) | 3.18682166 |
76 | sodium ion export (GO:0071436) | 3.18524037 |
77 | cellular potassium ion homeostasis (GO:0030007) | 3.18068837 |
78 | regulation of neurotransmitter secretion (GO:0046928) | 3.17314357 |
79 | regulation of synapse maturation (GO:0090128) | 3.16849914 |
80 | cell communication by electrical coupling (GO:0010644) | 3.16816730 |
81 | glycosphingolipid biosynthetic process (GO:0006688) | 3.15016307 |
82 | social behavior (GO:0035176) | 3.13633565 |
83 | intraspecies interaction between organisms (GO:0051703) | 3.13633565 |
84 | positive regulation of dendritic spine development (GO:0060999) | 3.13026378 |
85 | learning (GO:0007612) | 3.12780909 |
86 | membrane depolarization (GO:0051899) | 3.11458403 |
87 | cerebellar granule cell differentiation (GO:0021707) | 3.09092882 |
88 | establishment of mitochondrion localization (GO:0051654) | 3.08652472 |
89 | mitochondrion transport along microtubule (GO:0047497) | 3.07883170 |
90 | establishment of mitochondrion localization, microtubule-mediated (GO:0034643) | 3.07883170 |
91 | regulation of synaptic plasticity (GO:0048167) | 3.07714570 |
92 | negative regulation of synaptic transmission, glutamatergic (GO:0051967) | 3.07583104 |
93 | clathrin coat assembly (GO:0048268) | 3.05385510 |
94 | pyrimidine dimer repair (GO:0006290) | 3.05247738 |
95 | membrane depolarization during action potential (GO:0086010) | 3.05019484 |
96 | response to pheromone (GO:0019236) | 3.04092568 |
97 | regulation of neurotransmitter levels (GO:0001505) | 3.03738178 |
98 | long-term synaptic potentiation (GO:0060291) | 3.03427810 |
99 | neuromuscular process controlling balance (GO:0050885) | 3.03046028 |
100 | regulation of vesicle fusion (GO:0031338) | 3.02903617 |
101 | regulation of synapse assembly (GO:0051963) | 3.01788016 |
102 | innervation (GO:0060384) | 3.00911723 |
103 | regulation of mitochondrial fission (GO:0090140) | 2.99352316 |
104 | negative regulation of oligodendrocyte differentiation (GO:0048715) | 2.98877850 |
105 | acidic amino acid transport (GO:0015800) | 2.98720694 |
106 | transmission of nerve impulse (GO:0019226) | 2.98543806 |
107 | synaptic vesicle endocytosis (GO:0048488) | 2.98247551 |
108 | cell communication by electrical coupling involved in cardiac conduction (GO:0086064) | 2.98204793 |
109 | positive regulation of synapse assembly (GO:0051965) | 2.98193790 |
110 | hippocampus development (GO:0021766) | 2.97600340 |
111 | negative regulation of synaptic transmission, GABAergic (GO:0032229) | 2.97529329 |
112 | regulation of dendritic spine development (GO:0060998) | 2.97130568 |
113 | short-term memory (GO:0007614) | 2.96631167 |
114 | cerebellum development (GO:0021549) | 2.96257321 |
115 | dendritic spine organization (GO:0097061) | 2.94479836 |
116 | regulation of development, heterochronic (GO:0040034) | 2.93844430 |
117 | synapse organization (GO:0050808) | 2.93446104 |
118 | neuromuscular synaptic transmission (GO:0007274) | 2.93445917 |
119 | regulation of Arp2/3 complex-mediated actin nucleation (GO:0034315) | 2.93283367 |
120 | membrane hyperpolarization (GO:0060081) | 2.92279260 |
121 | adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191) | 2.86768997 |
122 | neuronal ion channel clustering (GO:0045161) | 2.79621946 |
123 | response to dietary excess (GO:0002021) | 2.74968765 |
124 | behavioral response to cocaine (GO:0048148) | 2.66483492 |
125 | neuronal stem cell maintenance (GO:0097150) | 2.63038603 |
126 | behavioral response to ethanol (GO:0048149) | 2.62958337 |
127 | G-protein coupled glutamate receptor signaling pathway (GO:0007216) | 2.62620589 |
128 | * cell-cell adhesion (GO:0098609) | 2.61336288 |
129 | L-glutamate transport (GO:0015813) | 2.61111985 |
130 | * cell-cell adhesion via plasma-membrane adhesion molecules (GO:0098742) | 2.60157817 |
131 | cerebral cortex neuron differentiation (GO:0021895) | 2.58629214 |
132 | establishment of synaptic vesicle localization (GO:0097480) | 2.58530195 |
133 | synaptic vesicle transport (GO:0048489) | 2.58530195 |
134 | establishment of vesicle localization (GO:0051650) | 2.57399814 |
135 | positive regulation of action potential (GO:0045760) | 2.57228584 |
136 | central nervous system neuron axonogenesis (GO:0021955) | 2.56896333 |
137 | * nervous system development (GO:0007399) | 2.55366110 |
138 | protein localization to cilium (GO:0061512) | 2.54880054 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EZH2_22144423_ChIP-Seq_EOC_Human | 5.88393316 |
2 | GBX2_23144817_ChIP-Seq_PC3_Human | 4.03211932 |
3 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 3.13224077 |
4 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 2.98522019 |
5 | * JARID2_20064375_ChIP-Seq_MESCs_Mouse | 2.94130604 |
6 | REST_21632747_ChIP-Seq_MESCs_Mouse | 2.84499780 |
7 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 2.69564844 |
8 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.68669469 |
9 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 2.61218169 |
10 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 2.60687059 |
11 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 2.60687059 |
12 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 2.56182506 |
13 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 2.50507390 |
14 | * SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 2.49869998 |
15 | * SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 2.48022586 |
16 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 2.42168406 |
17 | * MTF2_20144788_ChIP-Seq_MESCs_Mouse | 2.40284968 |
18 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 2.35940470 |
19 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 2.35673706 |
20 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 2.31873535 |
21 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 2.29614843 |
22 | DROSHA_22980978_ChIP-Seq_HELA_Human | 2.27781813 |
23 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 2.25146249 |
24 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.24155970 |
25 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 2.19837561 |
26 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.18110383 |
27 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 2.14853261 |
28 | AR_21572438_ChIP-Seq_LNCaP_Human | 2.08081906 |
29 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 2.02457395 |
30 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.00123032 |
31 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.97484808 |
32 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.83724550 |
33 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.74900030 |
34 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.70617762 |
35 | * SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.62846633 |
36 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.61436653 |
37 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.60811479 |
38 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.60709387 |
39 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.54315621 |
40 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.53984483 |
41 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.51025290 |
42 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.50359501 |
43 | P300_19829295_ChIP-Seq_ESCs_Human | 1.47602837 |
44 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.43117575 |
45 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.42572676 |
46 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.42058733 |
47 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 1.41592625 |
48 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 1.41092635 |
49 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.40774880 |
50 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.39145675 |
51 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 1.38042488 |
52 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.36714103 |
53 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.35098276 |
54 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.34717000 |
55 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.34147050 |
56 | AR_25329375_ChIP-Seq_VCAP_Human | 1.33132740 |
57 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.31445970 |
58 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.30500300 |
59 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.30415816 |
60 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.29996340 |
61 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 1.29126150 |
62 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 1.27583687 |
63 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.26509975 |
64 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.26220872 |
65 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.26083420 |
66 | RING1B_27294783_Chip-Seq_NPCs_Mouse | 1.25559648 |
67 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.25177802 |
68 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 1.24206935 |
69 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.23639389 |
70 | RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 1.22568327 |
71 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.22123482 |
72 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.20833968 |
73 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.20833968 |
74 | AR_19668381_ChIP-Seq_PC3_Human | 1.20671866 |
75 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.20465874 |
76 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.19083092 |
77 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.18485117 |
78 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.18027458 |
79 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 1.17991854 |
80 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.16164928 |
81 | EWS_26573619_Chip-Seq_HEK293_Human | 1.15978802 |
82 | STAT3_23295773_ChIP-Seq_U87_Human | 1.15655316 |
83 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 1.15407714 |
84 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.14863501 |
85 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.14199437 |
86 | VDR_22108803_ChIP-Seq_LS180_Human | 1.13262549 |
87 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.12721055 |
88 | YAP1_20516196_ChIP-Seq_MESCs_Mouse | 1.12192663 |
89 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.11894330 |
90 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 1.08417412 |
91 | SOX9_26525672_Chip-Seq_HEART_Mouse | 1.06159185 |
92 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.06156344 |
93 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.05305834 |
94 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.05145687 |
95 | WT1_25993318_ChIP-Seq_PODOCYTE_Human | 1.04244636 |
96 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 1.03642296 |
97 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 1.03296134 |
98 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 1.02504924 |
99 | TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 1.01559085 |
100 | TCF4_23295773_ChIP-Seq_U87_Human | 1.00820901 |
101 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.00583262 |
102 | KDM2B_26808549_Chip-Seq_K562_Human | 1.00152109 |
103 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.00142691 |
104 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 0.98990476 |
105 | MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 0.96509014 |
106 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 0.96389778 |
107 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.96070816 |
108 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 0.96070816 |
109 | RUNX2_22187159_ChIP-Seq_PCA_Human | 0.95576461 |
110 | JUN_21703547_ChIP-Seq_K562_Human | 0.94542318 |
111 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 0.94160707 |
112 | EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 0.93986839 |
113 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 0.93453320 |
114 | SMAD3_21741376_ChIP-Seq_ESCs_Human | 0.93381843 |
115 | SMAD4_21741376_ChIP-Seq_HESCs_Human | 0.93052259 |
116 | SOX2_18358816_ChIP-ChIP_MESCs_Mouse | 0.92684179 |
117 | KDM2B_26808549_Chip-Seq_REH_Human | 0.92004257 |
118 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 0.91565020 |
119 | OLIG2_26023283_ChIP-Seq_AINV15_Mouse | 0.90909145 |
120 | TBX3_20139965_ChIP-Seq_MESCs_Mouse | 0.90738939 |
121 | TBX3_20139965_ChIP-Seq_ESCs_Mouse | 0.90471187 |
122 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.90304053 |
123 | ER_23166858_ChIP-Seq_MCF-7_Human | 0.90154769 |
124 | CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse | 0.89587189 |
125 | REST_19997604_ChIP-ChIP_NEURONS_Mouse | 0.89116446 |
126 | FUS_26573619_Chip-Seq_HEK293_Human | 0.88813457 |
127 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.87061015 |
128 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.86638128 |
129 | TAL1_26923725_Chip-Seq_HPCs_Mouse | 0.85825413 |
130 | POU5F1_18347094_ChIP-ChIP_MESCs_Mouse | 0.85087043 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0004859_abnormal_synaptic_plasticity | 6.11123975 |
2 | MP0003880_abnormal_central_pattern | 4.48018119 |
3 | MP0003635_abnormal_synaptic_transmissio | 3.96253331 |
4 | MP0004270_analgesia | 3.77615109 |
5 | MP0002063_abnormal_learning/memory/cond | 3.31747894 |
6 | MP0009745_abnormal_behavioral_response | 3.07869510 |
7 | MP0001968_abnormal_touch/_nociception | 3.03406968 |
8 | MP0005423_abnormal_somatic_nervous | 2.98428713 |
9 | MP0002064_seizures | 2.82482234 |
10 | MP0002572_abnormal_emotion/affect_behav | 2.78768440 |
11 | MP0009046_muscle_twitch | 2.73659946 |
12 | MP0002734_abnormal_mechanical_nocicepti | 2.73184658 |
13 | MP0001529_abnormal_vocalization | 2.65877651 |
14 | MP0002735_abnormal_chemical_nociception | 2.54806994 |
15 | MP0001486_abnormal_startle_reflex | 2.47037628 |
16 | MP0002822_catalepsy | 2.44126805 |
17 | MP0002736_abnormal_nociception_after | 2.36756239 |
18 | MP0006276_abnormal_autonomic_nervous | 2.34581673 |
19 | MP0000778_abnormal_nervous_system | 2.29219198 |
20 | MP0002272_abnormal_nervous_system | 2.23604627 |
21 | MP0002733_abnormal_thermal_nociception | 2.19695467 |
22 | MP0002184_abnormal_innervation | 2.18756013 |
23 | MP0001440_abnormal_grooming_behavior | 2.16229883 |
24 | MP0009780_abnormal_chondrocyte_physiolo | 2.07800048 |
25 | MP0002067_abnormal_sensory_capabilities | 2.03594617 |
26 | MP0001970_abnormal_pain_threshold | 2.02285728 |
27 | MP0004811_abnormal_neuron_physiology | 1.96773659 |
28 | MP0010386_abnormal_urinary_bladder | 1.95402740 |
29 | MP0004924_abnormal_behavior | 1.88703590 |
30 | MP0005386_behavior/neurological_phenoty | 1.88703590 |
31 | MP0008569_lethality_at_weaning | 1.87572397 |
32 | MP0002557_abnormal_social/conspecific_i | 1.86679015 |
33 | MP0004858_abnormal_nervous_system | 1.84826539 |
34 | MP0001501_abnormal_sleep_pattern | 1.83755399 |
35 | MP0000569_abnormal_digit_pigmentation | 1.82446014 |
36 | MP0003329_amyloid_beta_deposits | 1.75831580 |
37 | MP0008789_abnormal_olfactory_epithelium | 1.59538458 |
38 | MP0002909_abnormal_adrenal_gland | 1.59054250 |
39 | MP0003879_abnormal_hair_cell | 1.58730310 |
40 | MP0001984_abnormal_olfaction | 1.58477890 |
41 | MP0001905_abnormal_dopamine_level | 1.58222461 |
42 | MP0000955_abnormal_spinal_cord | 1.58161665 |
43 | MP0002638_abnormal_pupillary_reflex | 1.57381860 |
44 | MP0002102_abnormal_ear_morphology | 1.55709108 |
45 | MP0002882_abnormal_neuron_morphology | 1.51736453 |
46 | MP0005367_renal/urinary_system_phenotyp | 1.49044349 |
47 | MP0000516_abnormal_urinary_system | 1.49044349 |
48 | MP0003890_abnormal_embryonic-extraembry | 1.42736484 |
49 | MP0002066_abnormal_motor_capabilities/c | 1.37178376 |
50 | MP0001502_abnormal_circadian_rhythm | 1.32268010 |
51 | MP0005646_abnormal_pituitary_gland | 1.31328569 |
52 | MP0005248_abnormal_Harderian_gland | 1.30752089 |
53 | MP0003121_genomic_imprinting | 1.30417440 |
54 | MP0001188_hyperpigmentation | 1.29834460 |
55 | MP0000049_abnormal_middle_ear | 1.28812922 |
56 | MP0002152_abnormal_brain_morphology | 1.23919832 |
57 | MP0002653_abnormal_ependyma_morphology | 1.21901823 |
58 | MP0008961_abnormal_basal_metabolism | 1.20648327 |
59 | MP0002837_dystrophic_cardiac_calcinosis | 1.18663154 |
60 | MP0003221_abnormal_cardiomyocyte_apopto | 1.17153846 |
61 | MP0000751_myopathy | 1.15995882 |
62 | MP0004885_abnormal_endolymph | 1.14929853 |
63 | MP0003787_abnormal_imprinting | 1.14076208 |
64 | MP0003122_maternal_imprinting | 1.12499539 |
65 | MP0003137_abnormal_impulse_conducting | 1.12370364 |
66 | MP0005253_abnormal_eye_physiology | 1.08115395 |
67 | MP0001986_abnormal_taste_sensitivity | 1.06955744 |
68 | MP0003633_abnormal_nervous_system | 1.05733893 |
69 | MP0003938_abnormal_ear_development | 1.05306055 |
70 | MP0003119_abnormal_digestive_system | 1.05028315 |
71 | MP0004142_abnormal_muscle_tone | 1.04470419 |
72 | MP0003011_delayed_dark_adaptation | 1.04395169 |
73 | MP0004742_abnormal_vestibular_system | 1.00221641 |
74 | MP0002234_abnormal_pharynx_morphology | 0.99068286 |
75 | MP0000534_abnormal_ureter_morphology | 0.96619973 |
76 | MP0005645_abnormal_hypothalamus_physiol | 0.96596939 |
77 | MP0002229_neurodegeneration | 0.96496153 |
78 | MP0004145_abnormal_muscle_electrophysio | 0.95656169 |
79 | MP0006292_abnormal_olfactory_placode | 0.94284322 |
80 | MP0005551_abnormal_eye_electrophysiolog | 0.94237422 |
81 | MP0003631_nervous_system_phenotype | 0.93478369 |
82 | MP0004085_abnormal_heartbeat | 0.91678300 |
83 | MP0004233_abnormal_muscle_weight | 0.91606523 |
84 | MP0000026_abnormal_inner_ear | 0.91426800 |
85 | MP0002069_abnormal_eating/drinking_beha | 0.91143190 |
86 | MP0004215_abnormal_myocardial_fiber | 0.90222713 |
87 | MP0000566_synostosis | 0.89810955 |
88 | MP0002233_abnormal_nose_morphology | 0.88342213 |
89 | MP0000631_abnormal_neuroendocrine_gland | 0.87976504 |
90 | MP0002752_abnormal_somatic_nervous | 0.86625749 |
91 | MP0001485_abnormal_pinna_reflex | 0.84181014 |
92 | MP0008872_abnormal_physiological_respon | 0.83739021 |
93 | MP0002751_abnormal_autonomic_nervous | 0.82765101 |
94 | MP0004130_abnormal_muscle_cell | 0.82415351 |
95 | MP0003861_abnormal_nervous_system | 0.82313177 |
96 | MP0003634_abnormal_glial_cell | 0.82109794 |
97 | MP0005187_abnormal_penis_morphology | 0.79232412 |
98 | MP0001293_anophthalmia | 0.77997690 |
99 | MP0001963_abnormal_hearing_physiology | 0.77062030 |
100 | MP0001348_abnormal_lacrimal_gland | 0.76243634 |
101 | MP0002938_white_spotting | 0.73459822 |
102 | MP0000604_amyloidosis | 0.72755160 |
103 | MP0002249_abnormal_larynx_morphology | 0.72555612 |
104 | MP0001299_abnormal_eye_distance/ | 0.72232633 |
105 | MP0000013_abnormal_adipose_tissue | 0.71929768 |
106 | MP0002090_abnormal_vision | 0.71262350 |
107 | MP0005391_vision/eye_phenotype | 0.70179881 |
108 | MP0002081_perinatal_lethality | 0.69751542 |
109 | MP0008877_abnormal_DNA_methylation | 0.69536479 |
110 | MP0002876_abnormal_thyroid_physiology | 0.69146324 |
111 | MP0001664_abnormal_digestion | 0.68502002 |
112 | MP0003385_abnormal_body_wall | 0.67700528 |
113 | MP0003183_abnormal_peptide_metabolism | 0.66389450 |
114 | MP0003632_abnormal_nervous_system | 0.64473418 |
115 | MP0008874_decreased_physiological_sensi | 0.64371343 |
116 | MP0005394_taste/olfaction_phenotype | 0.62958080 |
117 | MP0005499_abnormal_olfactory_system | 0.62958080 |
118 | MP0010770_preweaning_lethality | 0.60307035 |
119 | MP0002082_postnatal_lethality | 0.60307035 |
120 | MP0001943_abnormal_respiration | 0.60023185 |
121 | MP0006072_abnormal_retinal_apoptosis | 0.59949826 |
122 | MP0005535_abnormal_body_temperature | 0.59828779 |
123 | MP0010769_abnormal_survival | 0.58501953 |
124 | MP0000538_abnormal_urinary_bladder | 0.57412865 |
125 | MP0004133_heterotaxia | 0.57193030 |
126 | MP0001177_atelectasis | 0.55014503 |
127 | MP0010768_mortality/aging | 0.54600196 |
128 | MP0003956_abnormal_body_size | 0.49978309 |
129 | MP0002089_abnormal_postnatal_growth/wei | 0.49958658 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Focal motor seizures (HP:0011153) | 6.55518941 |
2 | Myokymia (HP:0002411) | 6.19196803 |
3 | Epileptic encephalopathy (HP:0200134) | 5.31264966 |
4 | Focal seizures (HP:0007359) | 5.06220801 |
5 | Visual hallucinations (HP:0002367) | 4.57131114 |
6 | Febrile seizures (HP:0002373) | 4.29085799 |
7 | Atonic seizures (HP:0010819) | 4.23182569 |
8 | Absence seizures (HP:0002121) | 3.91477235 |
9 | Progressive cerebellar ataxia (HP:0002073) | 3.74699966 |
10 | Action tremor (HP:0002345) | 3.69976179 |
11 | Mutism (HP:0002300) | 3.67870387 |
12 | Papilledema (HP:0001085) | 3.57664338 |
13 | Supranuclear gaze palsy (HP:0000605) | 3.57207901 |
14 | Dialeptic seizures (HP:0011146) | 3.57167603 |
15 | Generalized tonic-clonic seizures (HP:0002069) | 3.56065202 |
16 | Broad-based gait (HP:0002136) | 3.51042776 |
17 | Hyperventilation (HP:0002883) | 3.46885886 |
18 | Poor eye contact (HP:0000817) | 3.40555734 |
19 | Limb dystonia (HP:0002451) | 3.38629563 |
20 | Excessive salivation (HP:0003781) | 3.25415300 |
21 | Drooling (HP:0002307) | 3.25415300 |
22 | Amblyopia (HP:0000646) | 3.24775872 |
23 | Ankle clonus (HP:0011448) | 3.23388605 |
24 | Split foot (HP:0001839) | 3.20909680 |
25 | Nephrogenic diabetes insipidus (HP:0009806) | 3.20601113 |
26 | Congenital primary aphakia (HP:0007707) | 3.19541818 |
27 | Cortical dysplasia (HP:0002539) | 3.18063723 |
28 | Truncal ataxia (HP:0002078) | 3.17906008 |
29 | Abnormality of the corticospinal tract (HP:0002492) | 3.14634196 |
30 | Abnormality of the lower motor neuron (HP:0002366) | 3.11872815 |
31 | Urinary urgency (HP:0000012) | 3.07322321 |
32 | Impaired social interactions (HP:0000735) | 3.06265277 |
33 | Abnormal social behavior (HP:0012433) | 3.06265277 |
34 | Amyotrophic lateral sclerosis (HP:0007354) | 3.03093511 |
35 | Insidious onset (HP:0003587) | 3.00576927 |
36 | Termporal pattern (HP:0011008) | 3.00576927 |
37 | Medial flaring of the eyebrow (HP:0010747) | 2.95529251 |
38 | Abnormal eating behavior (HP:0100738) | 2.88147020 |
39 | Impaired vibration sensation in the lower limbs (HP:0002166) | 2.87705585 |
40 | Progressive inability to walk (HP:0002505) | 2.85731984 |
41 | Polyphagia (HP:0002591) | 2.85282339 |
42 | Urinary bladder sphincter dysfunction (HP:0002839) | 2.84655756 |
43 | Epileptiform EEG discharges (HP:0011182) | 2.78471774 |
44 | Depression (HP:0000716) | 2.75293413 |
45 | Spastic gait (HP:0002064) | 2.72563003 |
46 | Pheochromocytoma (HP:0002666) | 2.69810937 |
47 | Neonatal respiratory distress (HP:0002643) | 2.69449499 |
48 | EEG with generalized epileptiform discharges (HP:0011198) | 2.68526531 |
49 | Torticollis (HP:0000473) | 2.65262923 |
50 | Inability to walk (HP:0002540) | 2.64260452 |
51 | Vaginal atresia (HP:0000148) | 2.62962041 |
52 | Genital tract atresia (HP:0001827) | 2.55784080 |
53 | Cerebral inclusion bodies (HP:0100314) | 2.55672994 |
54 | Hypsarrhythmia (HP:0002521) | 2.55504915 |
55 | Gaze-evoked nystagmus (HP:0000640) | 2.55279263 |
56 | Retinal dysplasia (HP:0007973) | 2.49753024 |
57 | Anxiety (HP:0000739) | 2.49351496 |
58 | Hyperglycinemia (HP:0002154) | 2.48024382 |
59 | Hemiparesis (HP:0001269) | 2.46860683 |
60 | Dysdiadochokinesis (HP:0002075) | 2.46447551 |
61 | Abnormality of the musculature of the pelvis (HP:0001469) | 2.44585900 |
62 | Abnormality of the hip-girdle musculature (HP:0001445) | 2.44585900 |
63 | Neurofibrillary tangles (HP:0002185) | 2.43391189 |
64 | Gait imbalance (HP:0002141) | 2.42046489 |
65 | Akinesia (HP:0002304) | 2.38824379 |
66 | Neuroendocrine neoplasm (HP:0100634) | 2.38738629 |
67 | Pachygyria (HP:0001302) | 2.38405411 |
68 | Impaired smooth pursuit (HP:0007772) | 2.36704853 |
69 | Dysmetria (HP:0001310) | 2.36279380 |
70 | Focal dystonia (HP:0004373) | 2.31257742 |
71 | Postural instability (HP:0002172) | 2.28041996 |
72 | Poor coordination (HP:0002370) | 2.27734237 |
73 | Genetic anticipation (HP:0003743) | 2.27171852 |
74 | Lower limb muscle weakness (HP:0007340) | 2.25338566 |
75 | Agitation (HP:0000713) | 2.25238403 |
76 | Craniofacial dystonia (HP:0012179) | 2.24555258 |
77 | Diplopia (HP:0000651) | 2.22329247 |
78 | Abnormality of binocular vision (HP:0011514) | 2.22329247 |
79 | Morphological abnormality of the pyramidal tract (HP:0002062) | 2.21984649 |
80 | Hypoplastic pelvis (HP:0008839) | 2.21162697 |
81 | High anterior hairline (HP:0009890) | 2.20252907 |
82 | Bradykinesia (HP:0002067) | 2.18849549 |
83 | Hypoplasia of the corpus callosum (HP:0002079) | 2.17684796 |
84 | Scanning speech (HP:0002168) | 2.17299829 |
85 | Aplasia/Hypoplasia of the brainstem (HP:0007362) | 2.16209787 |
86 | Hypoplasia of the brainstem (HP:0002365) | 2.16209787 |
87 | Megalencephaly (HP:0001355) | 2.15418317 |
88 | Stereotypic behavior (HP:0000733) | 2.13397507 |
89 | Specific learning disability (HP:0001328) | 2.13368796 |
90 | Protruding tongue (HP:0010808) | 2.11051094 |
91 | Hyperthyroidism (HP:0000836) | 2.10046588 |
92 | Abnormality of salivation (HP:0100755) | 2.09846092 |
93 | Thyroid-stimulating hormone excess (HP:0002925) | 2.09786412 |
94 | Inappropriate behavior (HP:0000719) | 2.09367863 |
95 | Absent speech (HP:0001344) | 2.07846175 |
96 | Renal hypoplasia (HP:0000089) | 2.05671429 |
97 | Abnormality of ocular smooth pursuit (HP:0000617) | 2.04276948 |
98 | Morphological abnormality of the middle ear (HP:0008609) | 2.04095401 |
99 | Atrophy/Degeneration involving motor neurons (HP:0007373) | 2.03179861 |
100 | Exotropia (HP:0000577) | 2.02295558 |
101 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 2.01832345 |
102 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 2.01832345 |
103 | Hypoventilation (HP:0002791) | 2.01306106 |
104 | Decreased testicular size (HP:0008734) | 2.00686423 |
105 | Colon cancer (HP:0003003) | 1.99955276 |
106 | Fetal akinesia sequence (HP:0001989) | 1.99830034 |
107 | Apathy (HP:0000741) | 1.99721057 |
108 | Obstructive sleep apnea (HP:0002870) | 1.99078743 |
109 | Tubulointerstitial nephritis (HP:0001970) | 1.98490829 |
110 | Insomnia (HP:0100785) | 1.97087499 |
111 | Lissencephaly (HP:0001339) | 1.96960805 |
112 | Failure to thrive in infancy (HP:0001531) | 1.95689831 |
113 | Abnormal hair whorl (HP:0010721) | 1.94673731 |
114 | Lower limb amyotrophy (HP:0007210) | 1.94194750 |
115 | Rib fusion (HP:0000902) | 1.93452418 |
116 | Abnormality of the astrocytes (HP:0100707) | 1.92898309 |
117 | Astrocytoma (HP:0009592) | 1.92898309 |
118 | Restlessness (HP:0000711) | 1.92460004 |
119 | Shoulder girdle muscle weakness (HP:0003547) | 1.92219824 |
120 | Narrow forehead (HP:0000341) | 1.91564965 |
121 | Esotropia (HP:0000565) | 1.89873523 |
122 | Poor suck (HP:0002033) | 1.87805801 |
123 | Intention tremor (HP:0002080) | 1.87648501 |
124 | Delusions (HP:0000746) | 1.87584853 |
125 | Ependymoma (HP:0002888) | 1.87234767 |
126 | Broad foot (HP:0001769) | 1.86540069 |
127 | Spastic tetraplegia (HP:0002510) | 1.86195400 |
128 | Polymicrogyria (HP:0002126) | 1.85874762 |
129 | Diminished motivation (HP:0000745) | 1.82629071 |
130 | Gastroesophageal reflux (HP:0002020) | 1.81544483 |
131 | Intestinal atresia (HP:0011100) | 1.81091850 |
132 | Pelvic girdle muscle weakness (HP:0003749) | 1.81025422 |
133 | Sleep apnea (HP:0010535) | 1.80372120 |
134 | Hepatoblastoma (HP:0002884) | 1.79356206 |
135 | Generalized myoclonic seizures (HP:0002123) | 1.78899747 |
136 | Heterochromia iridis (HP:0001100) | 1.78838165 |
137 | Methylmalonic acidemia (HP:0002912) | 1.78584890 |
138 | Papillary thyroid carcinoma (HP:0002895) | 1.78254446 |
139 | Muscular hypotonia of the trunk (HP:0008936) | 1.78072076 |
140 | Pointed chin (HP:0000307) | 1.74939072 |
141 | Pendular nystagmus (HP:0012043) | 1.74881943 |
142 | Medulloblastoma (HP:0002885) | 1.74389429 |
143 | Decreased number of large peripheral myelinated nerve fibers (HP:0003387) | 1.73727940 |
144 | Neoplasm of the peripheral nervous system (HP:0100007) | 1.72748191 |
145 | True hermaphroditism (HP:0010459) | 1.71285647 |
146 | Optic nerve hypoplasia (HP:0000609) | 1.70998144 |
147 | Postaxial hand polydactyly (HP:0001162) | 1.69123622 |
148 | Postnatal microcephaly (HP:0005484) | 1.67000812 |
149 | Dyskinesia (HP:0100660) | 1.64213924 |
150 | Cerebral hypomyelination (HP:0006808) | 1.62370134 |
151 | Aplasia/Hypoplasia of the lens (HP:0008063) | 1.62273549 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MARK1 | 5.52652481 |
2 | MAP3K9 | 4.14062873 |
3 | CASK | 3.52938647 |
4 | NTRK3 | 3.29998047 |
5 | MAP3K4 | 3.29943549 |
6 | MINK1 | 3.07849767 |
7 | MAP2K7 | 2.94675085 |
8 | NTRK2 | 2.75091012 |
9 | TRIM28 | 2.71134685 |
10 | EPHA4 | 2.30176897 |
11 | DAPK2 | 2.23591307 |
12 | DYRK2 | 2.21295955 |
13 | MAP2K4 | 1.95918730 |
14 | MAPK13 | 1.91633472 |
15 | KSR1 | 1.76093672 |
16 | SRPK1 | 1.73269285 |
17 | MAP3K12 | 1.73098520 |
18 | PHKG2 | 1.69572439 |
19 | PHKG1 | 1.69572439 |
20 | PAK6 | 1.68293890 |
21 | SIK3 | 1.63142985 |
22 | CDK5 | 1.54523725 |
23 | NTRK1 | 1.46113575 |
24 | ERBB3 | 1.44443152 |
25 | SIK2 | 1.39389458 |
26 | CAMKK1 | 1.39239073 |
27 | BCKDK | 1.33347079 |
28 | CSNK1G1 | 1.32064045 |
29 | LATS2 | 1.31759944 |
30 | CDK19 | 1.29780037 |
31 | PLK2 | 1.29741917 |
32 | KSR2 | 1.29611329 |
33 | RPS6KA4 | 1.29451863 |
34 | MAP4K2 | 1.28889521 |
35 | DAPK1 | 1.27872141 |
36 | STK38L | 1.27464735 |
37 | GRK5 | 1.20044410 |
38 | TNIK | 1.18657786 |
39 | CAMKK2 | 1.13886333 |
40 | CCNB1 | 1.13813395 |
41 | PRKCG | 1.11509795 |
42 | UHMK1 | 1.11303035 |
43 | TYRO3 | 1.10917612 |
44 | TAF1 | 1.09179806 |
45 | PKN2 | 1.05912008 |
46 | RET | 1.05123612 |
47 | CDK18 | 1.03805579 |
48 | BCR | 1.02745379 |
49 | MAP3K2 | 1.02212201 |
50 | EPHA3 | 1.00246012 |
51 | TESK1 | 0.98932453 |
52 | PRPF4B | 0.96892075 |
53 | CDK15 | 0.95287267 |
54 | EPHB2 | 0.94930917 |
55 | CDK14 | 0.94372692 |
56 | CSNK1G2 | 0.93126867 |
57 | PNCK | 0.90740498 |
58 | PRKD3 | 0.90572464 |
59 | FGFR2 | 0.86638639 |
60 | CAMK2A | 0.85772238 |
61 | MARK2 | 0.83909002 |
62 | CDK11A | 0.82986396 |
63 | EEF2K | 0.78525472 |
64 | SGK494 | 0.78434255 |
65 | SGK223 | 0.78434255 |
66 | STK38 | 0.74763306 |
67 | LIMK1 | 0.74163258 |
68 | DYRK1B | 0.73718736 |
69 | DYRK1A | 0.73564687 |
70 | PRKCZ | 0.72419802 |
71 | PINK1 | 0.69105604 |
72 | PAK3 | 0.69053637 |
73 | ARAF | 0.66736718 |
74 | TESK2 | 0.66613512 |
75 | FGFR3 | 0.66433374 |
76 | PRKCE | 0.63477666 |
77 | CAMK2B | 0.61714333 |
78 | RIPK4 | 0.61477236 |
79 | SCYL2 | 0.60320412 |
80 | LMTK2 | 0.57472666 |
81 | STK11 | 0.57412905 |
82 | MAP3K6 | 0.57381258 |
83 | MAPKAPK3 | 0.57175856 |
84 | RPS6KA2 | 0.55523674 |
85 | FYN | 0.55446278 |
86 | OXSR1 | 0.53835943 |
87 | CAMK2D | 0.52309781 |
88 | CAMK2G | 0.52033871 |
89 | CSNK1G3 | 0.51746140 |
90 | NEK1 | 0.51019618 |
91 | FGR | 0.51006141 |
92 | FES | 0.49534142 |
93 | EPHB1 | 0.49186301 |
94 | MAPK12 | 0.49161144 |
95 | FER | 0.47996954 |
96 | NME1 | 0.47205668 |
97 | PKN1 | 0.46624334 |
98 | PRKACB | 0.45529317 |
99 | PTK2B | 0.44383355 |
100 | CSNK1E | 0.44177263 |
101 | CAMK1 | 0.43786571 |
102 | SGK1 | 0.43669265 |
103 | CSNK1D | 0.43477057 |
104 | RPS6KB1 | 0.42334300 |
105 | PRKCH | 0.41502842 |
106 | ICK | 0.40626950 |
107 | INSRR | 0.40189470 |
108 | WNK3 | 0.39717923 |
109 | RPS6KA3 | 0.39060329 |
110 | RAF1 | 0.38801148 |
111 | MAP3K5 | 0.38130155 |
112 | MAPK9 | 0.36174224 |
113 | TSSK6 | 0.36127684 |
114 | CSNK1A1L | 0.35160003 |
115 | BMPR1B | 0.35153687 |
116 | ALK | 0.35026094 |
117 | MAPKAPK5 | 0.34440850 |
118 | CAMK1G | 0.33069153 |
119 | PDGFRA | 0.33007655 |
120 | MST1R | 0.32605838 |
121 | BRAF | 0.32414009 |
122 | AKT3 | 0.31494513 |
123 | PRKACA | 0.31481555 |
124 | ERBB2 | 0.31132384 |
125 | DYRK3 | 0.30949057 |
126 | CDK3 | 0.30923146 |
127 | MKNK2 | 0.30912442 |
128 | CSNK1A1 | 0.30513567 |
129 | MAPK10 | 0.30347818 |
130 | MAP2K1 | 0.30089246 |
131 | SGK2 | 0.29846473 |
132 | CDC42BPA | 0.29644980 |
133 | ADRBK1 | 0.29020946 |
134 | TNK2 | 0.27994403 |
135 | CAMK4 | 0.27983064 |
136 | PDK1 | 0.27458827 |
137 | PRKCB | 0.27397955 |
138 | MKNK1 | 0.27220113 |
139 | PRKAA1 | 0.26701657 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Nicotine addiction_Homo sapiens_hsa05033 | 4.02260687 |
2 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 3.48526163 |
3 | Olfactory transduction_Homo sapiens_hsa04740 | 2.67484987 |
4 | GABAergic synapse_Homo sapiens_hsa04727 | 2.63994231 |
5 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 2.63399663 |
6 | Circadian entrainment_Homo sapiens_hsa04713 | 2.62148194 |
7 | Morphine addiction_Homo sapiens_hsa05032 | 2.41274930 |
8 | Glutamatergic synapse_Homo sapiens_hsa04724 | 2.37586869 |
9 | Long-term potentiation_Homo sapiens_hsa04720 | 2.34102446 |
10 | Amphetamine addiction_Homo sapiens_hsa05031 | 2.27261649 |
11 | Dopaminergic synapse_Homo sapiens_hsa04728 | 2.24400962 |
12 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 2.23794001 |
13 | Cholinergic synapse_Homo sapiens_hsa04725 | 2.06217390 |
14 | Steroid biosynthesis_Homo sapiens_hsa00100 | 2.02899871 |
15 | Salivary secretion_Homo sapiens_hsa04970 | 1.91759129 |
16 | Insulin secretion_Homo sapiens_hsa04911 | 1.83308668 |
17 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.82902584 |
18 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 1.80564027 |
19 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.71642833 |
20 | Cocaine addiction_Homo sapiens_hsa05030 | 1.68624858 |
21 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.63786709 |
22 | Renin secretion_Homo sapiens_hsa04924 | 1.63234727 |
23 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.62929090 |
24 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.60956891 |
25 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.57919305 |
26 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 1.57904856 |
27 | Taste transduction_Homo sapiens_hsa04742 | 1.57263536 |
28 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 1.56765442 |
29 | Gap junction_Homo sapiens_hsa04540 | 1.52842077 |
30 | Axon guidance_Homo sapiens_hsa04360 | 1.51688590 |
31 | Gastric acid secretion_Homo sapiens_hsa04971 | 1.50797921 |
32 | Long-term depression_Homo sapiens_hsa04730 | 1.49995477 |
33 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.37185829 |
34 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.32518495 |
35 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.32448164 |
36 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 1.30317121 |
37 | GnRH signaling pathway_Homo sapiens_hsa04912 | 1.27107920 |
38 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 1.23264784 |
39 | Protein export_Homo sapiens_hsa03060 | 1.16686398 |
40 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 1.13277900 |
41 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 1.12510756 |
42 | ErbB signaling pathway_Homo sapiens_hsa04012 | 1.12308150 |
43 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 1.11929462 |
44 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 1.11650988 |
45 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.11584587 |
46 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 1.11088364 |
47 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.09777507 |
48 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 1.07094099 |
49 | Glioma_Homo sapiens_hsa05214 | 1.06690106 |
50 | cAMP signaling pathway_Homo sapiens_hsa04024 | 1.06199556 |
51 | Phototransduction_Homo sapiens_hsa04744 | 1.05390596 |
52 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.02103609 |
53 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.97682426 |
54 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.97449708 |
55 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.94835824 |
56 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.94123429 |
57 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.93877849 |
58 | Melanogenesis_Homo sapiens_hsa04916 | 0.93304373 |
59 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.92125474 |
60 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.89609330 |
61 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.88411254 |
62 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.87314096 |
63 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.85472779 |
64 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.83221291 |
65 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.82936149 |
66 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.82652136 |
67 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.80292754 |
68 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.80144046 |
69 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.76555591 |
70 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.75413407 |
71 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.75389335 |
72 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.72606959 |
73 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.72445127 |
74 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.72285505 |
75 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.72199611 |
76 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.71479630 |
77 | Alcoholism_Homo sapiens_hsa05034 | 0.70652879 |
78 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.70627489 |
79 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.70453801 |
80 | Endometrial cancer_Homo sapiens_hsa05213 | 0.69465357 |
81 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.69149023 |
82 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.67093962 |
83 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.66581561 |
84 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.66152135 |
85 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.65274798 |
86 | Circadian rhythm_Homo sapiens_hsa04710 | 0.63853448 |
87 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.63609806 |
88 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.63258656 |
89 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.62468782 |
90 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.62034361 |
91 | Colorectal cancer_Homo sapiens_hsa05210 | 0.61918776 |
92 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.60617895 |
93 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.59103706 |
94 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.58760006 |
95 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.58667391 |
96 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.57891145 |
97 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.57614014 |
98 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.57316431 |
99 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.56933741 |
100 | Alzheimers disease_Homo sapiens_hsa05010 | 0.56500077 |
101 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.56142038 |
102 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.55635593 |
103 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.55061099 |
104 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.54511549 |
105 | Basal transcription factors_Homo sapiens_hsa03022 | 0.54057048 |
106 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.53174914 |
107 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.52440412 |
108 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.52421369 |
109 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.50700202 |
110 | Prion diseases_Homo sapiens_hsa05020 | 0.47156376 |
111 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.46734221 |
112 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.46526621 |
113 | Tight junction_Homo sapiens_hsa04530 | 0.46221125 |
114 | Peroxisome_Homo sapiens_hsa04146 | 0.46022742 |
115 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.45884383 |
116 | Huntingtons disease_Homo sapiens_hsa05016 | 0.45585079 |
117 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.45291629 |
118 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.44991578 |
119 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.44785357 |
120 | Endocytosis_Homo sapiens_hsa04144 | 0.44696554 |
121 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.44509678 |
122 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.44381029 |
123 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.41620996 |
124 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.41454354 |
125 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.39804203 |
126 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.39745423 |
127 | Bile secretion_Homo sapiens_hsa04976 | 0.39016568 |
128 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.38783204 |
129 | Carbon metabolism_Homo sapiens_hsa01200 | 0.38445962 |
130 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.36602676 |
131 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.36415576 |
132 | Phagosome_Homo sapiens_hsa04145 | 0.35198343 |
133 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.34562498 |
134 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.34148086 |
135 | Parkinsons disease_Homo sapiens_hsa05012 | 0.33315460 |
136 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.33181132 |
137 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.32751069 |
138 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.29973806 |