PCF11

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene binds to CLP1 to form pre-mRNA cleavage factor IIm. The encoded protein is necessary for efficient Pol II transcription termination and may be involved in degradation of the 3' product of polyA site cleavage. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1negative regulation of cAMP-mediated signaling (GO:0043951)4.45366149
2antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G4.34193247
3positive regulation of gamma-delta T cell activation (GO:0046645)4.18253387
4mitotic sister chromatid cohesion (GO:0007064)4.17147368
5regulation of histone H3-K27 methylation (GO:0061085)4.07921646
6nuclear pore complex assembly (GO:0051292)3.82901936
7positive regulation of granulocyte differentiation (GO:0030854)3.66676674
8regulation of DNA endoreduplication (GO:0032875)3.57859822
9regulation of interleukin-12 biosynthetic process (GO:0045075)3.47878772
10histone H3-K36 demethylation (GO:0070544)3.44746531
11negative regulation of translation involved in gene silencing by miRNA (GO:0035278)3.39537073
12negative regulation of translation, ncRNA-mediated (GO:0040033)3.39537073
13regulation of translation, ncRNA-mediated (GO:0045974)3.39537073
14cellular response to ethanol (GO:0071361)3.34033618
15cytoplasmic mRNA processing body assembly (GO:0033962)3.33209565
16positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO3.33202446
17regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:1900151)3.33202446
18histone H3-K4 trimethylation (GO:0080182)3.31138127
19hepatocyte apoptotic process (GO:0097284)3.31061307
20regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060211)3.25746651
21positive regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060213)3.25746651
22regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.24696854
23positive regulation of mRNA catabolic process (GO:0061014)3.21746169
24pore complex assembly (GO:0046931)3.13026185
25nuclear pore organization (GO:0006999)3.12445948
26negative regulation of T-helper cell differentiation (GO:0045623)3.11986199
27negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)3.11986199
28regulation of fibroblast apoptotic process (GO:2000269)3.07389150
29positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.07205404
30establishment of protein localization to Golgi (GO:0072600)3.05838705
31regulation of gamma-delta T cell activation (GO:0046643)3.04784109
32regulation of interferon-beta biosynthetic process (GO:0045357)3.04208502
33regulation of mRNA catabolic process (GO:0061013)3.03494473
34positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)3.01869533
35positive regulation of mitotic sister chromatid separation (GO:1901970)3.01176770
36positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.01176770
37positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.01176770
38regulation of gamma-delta T cell differentiation (GO:0045586)3.00609025
39definitive hemopoiesis (GO:0060216)3.00138667
40macrophage activation involved in immune response (GO:0002281)2.98178127
41negative regulation of glycoprotein biosynthetic process (GO:0010561)2.95528989
42interferon-gamma production (GO:0032609)2.94207584
43peptidyl-lysine methylation (GO:0018022)2.94116348
44positive T cell selection (GO:0043368)2.93616630
45monoubiquitinated protein deubiquitination (GO:0035520)2.93287724
46N-terminal protein amino acid acetylation (GO:0006474)2.89020795
47detection of molecule of bacterial origin (GO:0032490)2.87622735
48negative regulation of cytosolic calcium ion concentration (GO:0051481)2.85757601
49negative regulation of leukocyte mediated cytotoxicity (GO:0001911)2.84718343
50negative regulation of cell killing (GO:0031342)2.84718343
51negative regulation of lymphocyte mediated immunity (GO:0002707)2.83983662
52histone H3-K4 methylation (GO:0051568)2.83928487
53positive regulation of B cell differentiation (GO:0045579)2.80863762
54histone mRNA catabolic process (GO:0071044)2.79094434
55negative regulation of calcium ion-dependent exocytosis (GO:0045955)2.77970019
56retrograde transport, vesicle recycling within Golgi (GO:0000301)2.77915379
57positive thymic T cell selection (GO:0045059)2.76128487
58germinal center formation (GO:0002467)2.76104885
59regulation of granulocyte differentiation (GO:0030852)2.75984012
60regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition 2.75627541
61peptidyl-lysine trimethylation (GO:0018023)2.74766815
62protein targeting to Golgi (GO:0000042)2.73777720
63antigen processing and presentation of endogenous peptide antigen (GO:0002483)2.73756327
64negative regulation of T cell mediated immunity (GO:0002710)2.72922496
65NIK/NF-kappaB signaling (GO:0038061)2.72896502
66regulation of histone H3-K9 methylation (GO:0051570)2.69572156
67negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)2.69376685
68regulation of RNA export from nucleus (GO:0046831)2.68726245
69protein demethylation (GO:0006482)2.68049527
70protein dealkylation (GO:0008214)2.68049527
71positive regulation of interferon-alpha production (GO:0032727)2.67203364
72B cell homeostasis (GO:0001782)2.66632039
73negative regulation of B cell proliferation (GO:0030889)2.65669338
74regulation of protein polyubiquitination (GO:1902914)2.64021851
75thymic T cell selection (GO:0045061)2.63330796
76protein K48-linked deubiquitination (GO:0071108)2.60941710
77microglial cell activation (GO:0001774)2.60132727
78regulation of B cell differentiation (GO:0045577)2.59182860
79negative regulation of immunoglobulin mediated immune response (GO:0002890)2.59124692
80negative regulation of B cell mediated immunity (GO:0002713)2.59124692
81negative regulation of adaptive immune response based on somatic recombination of immune receptors b2.58978122
82NLS-bearing protein import into nucleus (GO:0006607)2.58837094
83interkinetic nuclear migration (GO:0022027)2.56672650
84response to peptidoglycan (GO:0032494)2.56305152
85histone H4-K16 acetylation (GO:0043984)2.54654502
86myeloid dendritic cell activation (GO:0001773)2.54403134
87positive regulation of alpha-beta T cell proliferation (GO:0046641)2.54312231
88response to interleukin-15 (GO:0070672)2.52742579
89negative regulation of granulocyte differentiation (GO:0030853)2.52027320
90negative regulation of phagocytosis (GO:0050765)2.51416714
91regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.51076916
92response to muramyl dipeptide (GO:0032495)2.50495633
93pyrimidine dimer repair (GO:0006290)2.49332798
94regulation of establishment of cell polarity (GO:2000114)2.48986400
95regulation of B cell receptor signaling pathway (GO:0050855)2.47831020
96neutrophil activation (GO:0042119)2.47723214
97regulation of protein glycosylation (GO:0060049)2.47272657
98negative T cell selection (GO:0043383)2.47195339
99negative regulation of erythrocyte differentiation (GO:0045647)2.47175403
100dendritic cell chemotaxis (GO:0002407)2.47031101
101positive regulation by symbiont of host defense response (GO:0052509)2.46950537
102modulation by symbiont of host defense response (GO:0052031)2.46950537
103modulation by organism of immune response of other organism involved in symbiotic interaction (GO:002.46950537
104modulation by organism of defense response of other organism involved in symbiotic interaction (GO:02.46950537
105positive regulation by organism of defense response of other organism involved in symbiotic interact2.46950537
106modulation by symbiont of host immune response (GO:0052553)2.46950537
107CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294)2.46590593
108T-helper cell differentiation (GO:0042093)2.46590593
109histone lysine demethylation (GO:0070076)2.45824131
110regulation of interferon-alpha production (GO:0032647)2.45629517
111antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)2.45554066
112histone H3-K9 demethylation (GO:0033169)2.45247317
113negative regulation of adaptive immune response (GO:0002820)2.44520150
114regulation of T cell tolerance induction (GO:0002664)2.44439187
115positive regulation of interferon-beta production (GO:0032728)2.43657671
116macrophage activation (GO:0042116)2.43308909
117phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)2.42569342
118embryonic hemopoiesis (GO:0035162)2.42006876
119negative regulation of histone methylation (GO:0031061)2.40177035
120regulation of alpha-beta T cell proliferation (GO:0046640)2.39763324
121cellular extravasation (GO:0045123)2.39136336
122histone demethylation (GO:0016577)2.36486233
123sister chromatid cohesion (GO:0007062)2.36177731
124histone H3-K9 methylation (GO:0051567)2.35582855
125megakaryocyte development (GO:0035855)2.35034383
126positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.34460416
127neutrophil activation involved in immune response (GO:0002283)2.33689358
128regulation of nucleobase-containing compound transport (GO:0032239)2.32770273
129negative thymic T cell selection (GO:0045060)2.32594472
130modulation by symbiont of host cellular process (GO:0044068)2.31353995
131leukocyte aggregation (GO:0070486)2.30929054
132T cell selection (GO:0045058)2.30875270
133granulocyte activation (GO:0036230)2.30372578
134histone lysine methylation (GO:0034968)2.28857753
135dendritic cell migration (GO:0036336)2.28317444
136antigen processing and presentation of endogenous antigen (GO:0019883)2.28033725
137positive regulation of protein import into nucleus, translocation (GO:0033160)2.27006638
138RNA stabilization (GO:0043489)2.26676455
139mRNA stabilization (GO:0048255)2.26676455
140negative regulation of DNA-dependent DNA replication (GO:2000104)2.26448577
141B cell receptor signaling pathway (GO:0050853)2.26365713
142histone H3-K9 modification (GO:0061647)2.22988611
143B cell proliferation (GO:0042100)2.22851148
144positive regulation of histone deacetylation (GO:0031065)2.22781923
145myeloid dendritic cell differentiation (GO:0043011)2.22719931
146embryonic camera-type eye morphogenesis (GO:0048596)2.19837550
147T cell migration (GO:0072678)2.19658659
148lymphocyte homeostasis (GO:0002260)2.16447827
149negative regulation of fibroblast apoptotic process (GO:2000270)2.16284925
150positive regulation of interleukin-2 production (GO:0032743)2.15709615

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXP3_17237761_ChIP-ChIP_TREG_Mouse4.96998076
2E2F7_22180533_ChIP-Seq_HELA_Human4.36777690
3EGR1_19374776_ChIP-ChIP_THP-1_Human4.19804883
4STAT6_20620947_ChIP-Seq_CD4_POS_T_Human3.83806739
5IRF8_22096565_ChIP-ChIP_GC-B_Human3.74470933
6FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse3.24041749
7STAT3_20064451_ChIP-Seq_CD4+T_Mouse3.11122971
8SALL1_21062744_ChIP-ChIP_HESCs_Human2.97152955
9NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.83361024
10FOXM1_23109430_ChIP-Seq_U2OS_Human2.74114729
11BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.71276347
12IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.45360356
13* SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.42427255
14FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse2.37110823
15IRF8_27001747_Chip-Seq_BMDM_Mouse2.27580853
16RUNX_20019798_ChIP-Seq_JUKART_Human2.26428029
17BP1_19119308_ChIP-ChIP_Hs578T_Human2.24122409
18GATA1_22025678_ChIP-Seq_K562_Human2.19895183
19MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.18316595
20CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.16031962
21NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.13058192
22SCL_19346495_ChIP-Seq_HPC-7_Human2.11189119
23Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse2.06047169
24IRF8_21731497_ChIP-ChIP_J774_Mouse2.05633074
25SMAD_19615063_ChIP-ChIP_OVARY_Human1.93044567
26MYB_26560356_Chip-Seq_TH2_Human1.91392378
27MYB_21317192_ChIP-Seq_ERMYB_Mouse1.91364512
28ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.88769564
29MYB_26560356_Chip-Seq_TH1_Human1.86055011
30STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.85252487
31IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.83948897
32PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.79351005
33* KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.76615315
34VDR_21846776_ChIP-Seq_THP-1_Human1.68347461
35E2F4_17652178_ChIP-ChIP_JURKAT_Human1.65259357
36SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.64983882
37TCF7_22412390_ChIP-Seq_EML_Mouse1.61190226
38STAT4_19710469_ChIP-ChIP_TH1__Mouse1.58455417
39TP63_19390658_ChIP-ChIP_HaCaT_Human1.58269133
40MYC_22102868_ChIP-Seq_BL_Human1.57924124
41SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.56343352
42* CIITA_25753668_ChIP-Seq_RAJI_Human1.55249750
43NOTCH1_21737748_ChIP-Seq_TLL_Human1.52708033
44E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.45921879
45BRD4_27068464_Chip-Seq_AML-cells_Mouse1.43896384
46PU_27001747_Chip-Seq_BMDM_Mouse1.41885957
47FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.38447176
48HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.37420771
49MAF_26560356_Chip-Seq_TH1_Human1.36584065
50GATA2_21666600_ChIP-Seq_HMVEC_Human1.32219648
51VDR_24787735_ChIP-Seq_THP-1_Human1.32016224
52AHR_22903824_ChIP-Seq_MCF-7_Human1.28405687
53ESR1_20079471_ChIP-ChIP_T-47D_Human1.28110270
54PKCTHETA_26484144_Chip-Seq_BREAST_Human1.27625159
55RUNX1_22412390_ChIP-Seq_EML_Mouse1.26453133
56* GATA3_27048872_Chip-Seq_THYMUS_Human1.25259930
57RBPJ_22232070_ChIP-Seq_NCS_Mouse1.23766156
58TAF15_26573619_Chip-Seq_HEK293_Human1.23593239
59PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.23061487
60RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.22075494
61VDR_24763502_ChIP-Seq_THP-1_Human1.21624365
62FLI1_27457419_Chip-Seq_LIVER_Mouse1.18923289
63ZNF217_24962896_ChIP-Seq_MCF-7_Human1.18882637
64CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.18474543
65MAF_26560356_Chip-Seq_TH2_Human1.18173873
66GATA1_19941826_ChIP-Seq_K562_Human1.18001348
67VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.17806572
68ER_23166858_ChIP-Seq_MCF-7_Human1.17370292
69POU3F2_20337985_ChIP-ChIP_501MEL_Human1.17027611
70RXR_22108803_ChIP-Seq_LS180_Human1.15950731
71RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.15863963
72KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.14707217
73SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.14401063
74SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.14401063
75GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.14310785
76BRD4_25478319_ChIP-Seq_HGPS_Human1.14174359
77FOXO3_23340844_ChIP-Seq_DLD1_Human1.14095188
78FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.13621530
79* SPI1_23547873_ChIP-Seq_NB4_Human1.12639171
80RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.11094832
81VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.09614516
82KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.09386475
83FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.06752244
84ARNT_22903824_ChIP-Seq_MCF-7_Human1.05752310
85NFIB_24661679_ChIP-Seq_LUNG_Mouse1.05331004
86E2F1_21310950_ChIP-Seq_MCF-7_Human1.04728468
87TCF4_18268006_ChIP-ChIP_LS174T_Human1.03930941
88UTX_26944678_Chip-Seq_JUKART_Human1.03905198
89AR_21572438_ChIP-Seq_LNCaP_Human1.01505932
90GATA2_19941826_ChIP-Seq_K562_Human1.00767985
91FUS_26573619_Chip-Seq_HEK293_Human0.99330644
92* SPI1_23127762_ChIP-Seq_K562_Human0.99152922
93KDM2B_26808549_Chip-Seq_DND41_Human0.98008441
94PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.97240383
95PCGF2_27294783_Chip-Seq_ESCs_Mouse0.95286065
96GATA1_19941827_ChIP-Seq_MEL86_Mouse0.92126114
97KDM2B_26808549_Chip-Seq_SUP-B15_Human0.90995199
98AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.90902598
99STAT3_23295773_ChIP-Seq_U87_Human0.90389481
100* STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.88253622
101TP53_16413492_ChIP-PET_HCT116_Human0.86806024
102GATA3_26560356_Chip-Seq_TH2_Human0.86332825
103DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.85640170
104GATA2_22383799_ChIP-Seq_G1ME_Mouse0.85438765
105POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.83644382
106TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.83644382
107TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.82985809
108BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.82755065
109SMRT_27268052_Chip-Seq_Bcells_Human0.82160484
110GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.80789478
111FOXM1_26456572_ChIP-Seq_MCF-7_Human0.80295718
112EZH2_27294783_Chip-Seq_NPCs_Mouse0.80158000
113NFE2_27457419_Chip-Seq_LIVER_Mouse0.80029986
114TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.79860123
115* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.79836501
116FOXA1_26743006_Chip-Seq_LNCaP-abl_Human0.79778866
117PCGF2_27294783_Chip-Seq_NPCs_Mouse0.79706777
118NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.79447028
119CJUN_26792858_Chip-Seq_BT549_Human0.79150827
120CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.78888225
121EWS_26573619_Chip-Seq_HEK293_Human0.78712186
122NANOG_18555785_Chip-Seq_ESCs_Mouse0.78586562
123GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.78243925
124* ETS1_22383799_ChIP-Seq_G1ME_Mouse0.77757900
125* FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human0.77681005
126CTNNB1_20460455_ChIP-Seq_HCT116_Human0.77294095
127SUZ12_27294783_Chip-Seq_NPCs_Mouse0.77128937
128CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.76393206

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000569_abnormal_digit_pigmentation4.06899017
2MP0001835_abnormal_antigen_presentation2.95760955
3MP0002166_altered_tumor_susceptibility2.63754482
4MP0002396_abnormal_hematopoietic_system2.48635594
5MP0002009_preneoplasia2.47698444
6MP0002006_tumorigenesis2.31598679
7MP0008057_abnormal_DNA_replication2.31286169
8MP0003300_gastrointestinal_ulcer2.31026375
9MP0003763_abnormal_thymus_physiology2.23073902
10MP0002877_abnormal_melanocyte_morpholog2.22851568
11MP0010352_gastrointestinal_tract_polyps2.22047849
12MP0004381_abnormal_hair_follicle2.18231035
13MP0001800_abnormal_humoral_immune2.10075838
14MP0004808_abnormal_hematopoietic_stem2.07731698
15MP0005671_abnormal_response_to2.03466192
16MP0009278_abnormal_bone_marrow2.03379078
17MP0003787_abnormal_imprinting2.01819265
18MP0001790_abnormal_immune_system1.95175898
19MP0005387_immune_system_phenotype1.95175898
20MP0002452_abnormal_antigen_presenting1.89205621
21MP0010307_abnormal_tumor_latency1.85683704
22MP0005076_abnormal_cell_differentiation1.82147870
23MP0000685_abnormal_immune_system1.76297746
24MP0005000_abnormal_immune_tolerance1.73384712
25MP0002398_abnormal_bone_marrow1.72931311
26MP0002420_abnormal_adaptive_immunity1.69901406
27MP0003436_decreased_susceptibility_to1.69857913
28MP0002723_abnormal_immune_serum1.69553677
29MP0001819_abnormal_immune_cell1.68319255
30MP0003656_abnormal_erythrocyte_physiolo1.65441135
31MP0001545_abnormal_hematopoietic_system1.65103799
32MP0005397_hematopoietic_system_phenotyp1.65103799
33MP0005174_abnormal_tail_pigmentation1.63802397
34MP0002419_abnormal_innate_immunity1.61001150
35MP0003303_peritoneal_inflammation1.58886843
36MP0002138_abnormal_hepatobiliary_system1.53145948
37MP0008877_abnormal_DNA_methylation1.53088633
38MP0008961_abnormal_basal_metabolism1.51544942
39MP0000703_abnormal_thymus_morphology1.50965525
40MP0002405_respiratory_system_inflammati1.50437052
41MP0004264_abnormal_extraembryonic_tissu1.47777950
42MP0000716_abnormal_immune_system1.46288847
43MP0001853_heart_inflammation1.43887448
44MP0002254_reproductive_system_inflammat1.42951794
45MP0010155_abnormal_intestine_physiology1.41715682
46MP0008007_abnormal_cellular_replicative1.40073703
47MP0001879_abnormal_lymphatic_vessel1.38191817
48MP0010094_abnormal_chromosome_stability1.37448972
49MP0003943_abnormal_hepatobiliary_system1.36467148
50MP0005025_abnormal_response_to1.35774733
51MP0004947_skin_inflammation1.33355450
52MP0002148_abnormal_hypersensitivity_rea1.27778588
53MP0000689_abnormal_spleen_morphology1.27731779
54MP0009785_altered_susceptibility_to1.27284859
55MP0002722_abnormal_immune_system1.27117973
56MP0008058_abnormal_DNA_repair1.25221805
57MP0005464_abnormal_platelet_physiology1.25079687
58MP0001873_stomach_inflammation1.21669662
59MP0003045_fibrosis1.21060618
60MP0000015_abnormal_ear_pigmentation1.20951819
61MP0002429_abnormal_blood_cell1.18197287
62MP0003828_pulmonary_edema1.17360391
63MP0000371_diluted_coat_color1.15998253
64MP0004130_abnormal_muscle_cell1.14843479
65MP0003448_altered_tumor_morphology1.12261908
66MP0002928_abnormal_bile_duct1.11720382
67MP0001845_abnormal_inflammatory_respons1.06949345
68MP0002132_abnormal_respiratory_system1.06766900
69MP0003077_abnormal_cell_cycle1.04565675
70MP0010234_abnormal_vibrissa_follicle1.04324730
71MP0001986_abnormal_taste_sensitivity1.02693595
72MP0006082_CNS_inflammation1.01819807
73MP0003183_abnormal_peptide_metabolism1.01404006
74MP0003091_abnormal_cell_migration1.00709313
75MP0003690_abnormal_glial_cell1.00297233
76MP0003221_abnormal_cardiomyocyte_apopto1.00151020
77MP0009764_decreased_sensitivity_to0.99125737
78MP0003111_abnormal_nucleus_morphology0.98765550
79MP0005310_abnormal_salivary_gland0.96829739
80MP0003724_increased_susceptibility_to0.96265977
81MP0000858_altered_metastatic_potential0.95412318
82MP0002095_abnormal_skin_pigmentation0.94879914
83MP0010678_abnormal_skin_adnexa0.94570479
84MP0003566_abnormal_cell_adhesion0.94459855
85MP0002998_abnormal_bone_remodeling0.94417045
86MP0009333_abnormal_splenocyte_physiolog0.94323134
87MP0001851_eye_inflammation0.92890487
88MP0005409_darkened_coat_color0.90502661
89MP0000465_gastrointestinal_hemorrhage0.90134663
90MP0002971_abnormal_brown_adipose0.89834736
91MP0003172_abnormal_lysosome_physiology0.88609390
92MP0004883_abnormal_blood_vessel0.87913221
93MP0000383_abnormal_hair_follicle0.86874931
94MP0000490_abnormal_crypts_of0.86478945
95MP0006054_spinal_hemorrhage0.84352973
96MP0005647_abnormal_sex_gland0.81387129
97MP0003866_abnormal_defecation0.81346162
98MP0002933_joint_inflammation0.81262590
99MP0002796_impaired_skin_barrier0.81039646
100MP0001533_abnormal_skeleton_physiology0.80892433
101MP0004510_myositis0.80224683
102MP0002277_abnormal_respiratory_mucosa0.79267851
103MP0001191_abnormal_skin_condition0.77544742
104MP0005367_renal/urinary_system_phenotyp0.77375720
105MP0000516_abnormal_urinary_system0.77375720
106MP0002075_abnormal_coat/hair_pigmentati0.76529565
107MP0002086_abnormal_extraembryonic_tissu0.75215277
108MP0000733_abnormal_muscle_development0.74315454
109MP0003453_abnormal_keratinocyte_physiol0.73485166
110MP0000350_abnormal_cell_proliferation0.72718185
111MP0005075_abnormal_melanosome_morpholog0.72032129
112MP0000627_abnormal_mammary_gland0.71784457
113MP0001915_intracranial_hemorrhage0.71211126
114MP0002925_abnormal_cardiovascular_devel0.71195230
115MP0002019_abnormal_tumor_incidence0.70552971
116MP0003795_abnormal_bone_structure0.70240530
117MP0005621_abnormal_cell_physiology0.70160938
118MP0004197_abnormal_fetal_growth/weight/0.69674199
119MP0005334_abnormal_fat_pad0.68894792
120MP0004185_abnormal_adipocyte_glucose0.68708501
121MP0009703_decreased_birth_body0.67465720
122MP0005083_abnormal_biliary_tract0.67404711
123MP0001784_abnormal_fluid_regulation0.66980199
124MP0009115_abnormal_fat_cell0.66716238
125MP0002876_abnormal_thyroid_physiology0.65302939
126MP0003984_embryonic_growth_retardation0.62712887
127MP0002088_abnormal_embryonic_growth/wei0.62543784

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of the fingertips (HP:0001211)4.29049506
2Volvulus (HP:0002580)3.41714022
3Prostate neoplasm (HP:0100787)3.34598739
4Thyroid-stimulating hormone excess (HP:0002925)3.05494067
5Eczematoid dermatitis (HP:0000976)2.97909174
6Hematochezia (HP:0002573)2.90534723
7Acute myeloid leukemia (HP:0004808)2.87813036
8Absent frontal sinuses (HP:0002688)2.84637556
9Recurrent fungal infections (HP:0002841)2.82677781
10Thyroiditis (HP:0100646)2.81720267
11Recurrent viral infections (HP:0004429)2.75077886
12Abnormality of the nasal septum (HP:0000419)2.72181841
13Elevated erythrocyte sedimentation rate (HP:0003565)2.70243791
14T lymphocytopenia (HP:0005403)2.68434435
15Autoimmune hemolytic anemia (HP:0001890)2.64535016
16Abnormality of T cell number (HP:0011839)2.62223865
17Recurrent abscess formation (HP:0002722)2.60482052
18Curly hair (HP:0002212)2.59356545
19Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.57026349
20Abnormality of the columella (HP:0009929)2.55018001
21Recurrent bacterial skin infections (HP:0005406)2.52351962
22Gastrointestinal infarctions (HP:0005244)2.50389511
23Recurrent cutaneous fungal infections (HP:0011370)2.47765303
24Chronic mucocutaneous candidiasis (HP:0002728)2.47765303
25Stomach cancer (HP:0012126)2.47152009
26Urethral obstruction (HP:0000796)2.40085936
27Chromsome breakage (HP:0040012)2.39488503
28Gaze-evoked nystagmus (HP:0000640)2.34119989
29Lip pit (HP:0100267)2.31575576
30Genetic anticipation (HP:0003743)2.30725809
31Thickened helices (HP:0000391)2.28727498
32Tented upper lip vermilion (HP:0010804)2.26985976
33Basal cell carcinoma (HP:0002671)2.25450844
34Chronic diarrhea (HP:0002028)2.24443551
35Chromosomal breakage induced by crosslinking agents (HP:0003221)2.24260995
36Agammaglobulinemia (HP:0004432)2.22275528
37Optic neuritis (HP:0100653)2.21409739
38Retrobulbar optic neuritis (HP:0100654)2.21409739
39Abnormality of the prostate (HP:0008775)2.21140136
40Macroorchidism (HP:0000053)2.20816704
41Panhypogammaglobulinemia (HP:0003139)2.20494277
42Mediastinal lymphadenopathy (HP:0100721)2.18105802
43Ectopic kidney (HP:0000086)2.18073011
44Cystic hygroma (HP:0000476)2.15859028
45Protruding tongue (HP:0010808)2.14275241
46Periodontitis (HP:0000704)2.14030221
47Spontaneous hematomas (HP:0007420)2.13953302
48Neonatal hypoglycemia (HP:0001998)2.13333013
49Neoplasm of the adrenal cortex (HP:0100641)2.13009077
50Abnormal delayed hypersensitivity skin test (HP:0002963)2.12170933
51Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)2.10640856
52Dysmetric saccades (HP:0000641)2.09338455
53Short chin (HP:0000331)2.08833295
54Nephroblastoma (Wilms tumor) (HP:0002667)2.06307252
55Abnormality of the frontal sinuses (HP:0002687)2.05050471
56Long clavicles (HP:0000890)2.04452206
57Sandal gap (HP:0001852)2.03492389
58Long eyelashes (HP:0000527)2.03085950
59Chest pain (HP:0100749)2.01248317
60Narrow palate (HP:0000189)1.98762747
61Syringomyelia (HP:0003396)1.98028114
62Spinal cord lesions (HP:0100561)1.98028114
63Hamartoma (HP:0010566)1.97810845
64Myositis (HP:0100614)1.96278479
65Abnormality of incisor morphology (HP:0011063)1.95355937
66Abnormality of T cell physiology (HP:0011840)1.95324966
67Stomatitis (HP:0010280)1.94871634
68Truncal obesity (HP:0001956)1.94698308
69Deep philtrum (HP:0002002)1.94550874
70Arterial thrombosis (HP:0004420)1.94312375
71Pustule (HP:0200039)1.94216366
72Papillary thyroid carcinoma (HP:0002895)1.93686963
73Short 4th metacarpal (HP:0010044)1.93252034
74Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.93252034
75Leukocytosis (HP:0001974)1.93016449
76Recurrent bronchitis (HP:0002837)1.91285008
77Cellulitis (HP:0100658)1.89781361
78Encephalitis (HP:0002383)1.89745744
79Embryonal renal neoplasm (HP:0011794)1.89266550
80Depressed nasal tip (HP:0000437)1.89134309
81Colitis (HP:0002583)1.88907251
82Hypochromic anemia (HP:0001931)1.88470385
83Orchitis (HP:0100796)1.88241090
84IgA deficiency (HP:0002720)1.86957822
85Fair hair (HP:0002286)1.86944484
86Eosinophilia (HP:0001880)1.86386281
87Neoplasm of the tracheobronchial system (HP:0100552)1.85877275
88Poikiloderma (HP:0001029)1.85617343
89Recurrent skin infections (HP:0001581)1.82676028
90Broad alveolar ridges (HP:0000187)1.82372867
91Gingivitis (HP:0000230)1.81198766
92Attenuation of retinal blood vessels (HP:0007843)1.80517253
93Vasculitis (HP:0002633)1.80511849
94B lymphocytopenia (HP:0010976)1.79802389
95Abnormality of B cell number (HP:0010975)1.79802389
96Oligodontia (HP:0000677)1.79056612
97Autoimmune thrombocytopenia (HP:0001973)1.78949592
98Hypoplastic labia majora (HP:0000059)1.78703398
99Prominent nose (HP:0000448)1.78624342
100Lymphopenia (HP:0001888)1.78445835
101Inflammation of the large intestine (HP:0002037)1.77126268
102Thick nail (HP:0001805)1.76862940
103IgM deficiency (HP:0002850)1.76363462
104Alveolar cell carcinoma (HP:0006519)1.76338363
105Abnormality of the axillary hair (HP:0100134)1.75934008
106Abnormality of secondary sexual hair (HP:0009888)1.75934008
107Meningitis (HP:0001287)1.75887725
108Granulocytopenia (HP:0001913)1.75856762
109Hypoplasia of the thymus (HP:0000778)1.75622863
110Slow saccadic eye movements (HP:0000514)1.75161650
111Abnormality of T cells (HP:0002843)1.75056235
112Osteomyelitis (HP:0002754)1.75046659
113Intestinal atresia (HP:0011100)1.74746982
114Increased IgE level (HP:0003212)1.74023463
115Acute lymphatic leukemia (HP:0006721)1.73827549
116Abnormality of cells of the lymphoid lineage (HP:0012140)1.73780735
117Transitional cell carcinoma of the bladder (HP:0006740)1.73266804
118Heterotopia (HP:0002282)1.73165651
119Severe combined immunodeficiency (HP:0004430)1.72910888
120Viral hepatitis (HP:0006562)1.71280072
121Subacute progressive viral hepatitis (HP:0006572)1.71278869
122Hemoptysis (HP:0002105)1.70886482
123Gastrointestinal stroma tumor (HP:0100723)1.70466385
124Facial hemangioma (HP:0000329)1.68050974
125Pulmonary infiltrates (HP:0002113)1.67544197
126Persistence of primary teeth (HP:0006335)1.65070832
127Abnormality of eosinophils (HP:0001879)1.64335930
128Aortic aneurysm (HP:0004942)1.64311372
129Cutis marmorata (HP:0000965)1.64092370
130Asymmetry of the thorax (HP:0001555)1.63646327
131Lymphoma (HP:0002665)1.63550959
132Keratoconjunctivitis sicca (HP:0001097)1.62971665
133Agnosia (HP:0010524)1.62631288
134Clubbing of toes (HP:0100760)1.62380188
135Dislocated radial head (HP:0003083)1.62328950
136Supernumerary ribs (HP:0005815)1.61521514
137Abnormality of chromosome stability (HP:0003220)1.61123498
138Keratoconjunctivitis (HP:0001096)1.60679807
139Hypoplastic ischia (HP:0003175)1.58692071
140Limited elbow extension (HP:0001377)1.58585515
141Gastrointestinal inflammation (HP:0004386)1.58188307
142Abnormal foot bone ossification (HP:0010675)1.57685263
143Aplasia/Hypoplasia involving the sinuses (HP:0009120)1.57627982

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDK123.44726132
2MAP3K143.42534238
3FRK2.77950547
4TXK2.46657355
5FGFR32.33190784
6BLK2.30786196
7INSRR2.23159687
8MAP4K12.22872951
9NUAK12.19247327
10MAP3K102.02469732
11BRD41.96371830
12ACVR1B1.91354782
13IRAK41.88326247
14CHUK1.75787902
15JAK31.70953389
16FGFR21.67172750
17TGFBR21.66694033
18ERN11.65606828
19ZAK1.54633666
20TEC1.54077824
21EPHA31.52141529
22ITK1.51456696
23CAMK1D1.49642658
24ADRBK21.47036237
25CAMK1G1.40092576
26CDK61.39669206
27STK101.39577834
28ERBB31.37026050
29JAK11.36332696
30IKBKE1.35683535
31IKBKB1.35086056
32TAOK31.33399281
33RPS6KA41.32161280
34LATS11.30809184
35MAP3K131.30604886
36TYK21.27255826
37SGK21.23180429
38PIK3CG1.21945963
39CDK91.20987914
40STK31.19917321
41PIM11.19651434
42PRPF4B1.17481185
43TNK21.16382886
44MAP3K31.15698113
45SGK31.13593899
46BRSK21.12250384
47STK41.10695216
48BMPR21.09417688
49KIT1.05488068
50NLK1.05000498
51ZAP701.04720559
52IRAK31.03487322
53BTK1.03381071
54YES11.01460386
55MKNK20.99719062
56FES0.97444179
57MAPK110.95692079
58EEF2K0.95262375
59RIPK10.93389828
60ATR0.92499253
61HIPK20.92134738
62RIPK40.91132417
63MAPK70.90703382
64PDGFRB0.90065209
65GRK60.89683199
66HCK0.87513284
67STK240.87055383
68MARK20.86271940
69RAF10.85921263
70MST40.85510419
71CLK10.85389291
72MAPK150.85325470
73TBK10.85015185
74MAP3K70.84582242
75TYRO30.82726874
76CSF1R0.82420197
77PNCK0.82292564
78NEK90.81660520
79LCK0.81634719
80ATM0.79960034
81FGFR40.79221673
82AKT30.78789231
83PTK60.78424086
84RPS6KB20.74407040
85PDK10.72947575
86CDK30.72679316
87TRPM70.71653597
88KSR20.69526620
89CSK0.69512955
90CDC70.68955078
91WNK10.68500435
92MAPK120.68306216
93SYK0.66589010
94PASK0.65989850
95MAP2K30.64566104
96IRAK20.64407932
97STK110.64335322
98SGK10.62729087
99CHEK10.62620704
100CAMKK20.62258496
101NEK20.60907628
102TRIB30.59339480
103JAK20.59217811
104MTOR0.58367983
105MKNK10.57493197
106SIK30.57407219
107PDK20.56790745
108MARK30.55497338
109MAP3K20.55025735
110FLT30.54823727
111EIF2AK30.54780355
112MELK0.54675798
113RPS6KB10.53318009
114IRAK10.52635586
115FGR0.52365963
116SGK4940.52183146
117SGK2230.52183146
118EPHB10.50100556
119CDK40.49304475
120LYN0.46802509
121PRKAA20.46755236
122KSR10.46293381
123DYRK30.45485756
124MAPK10.45097844
125MAPK80.44985995
126SRPK10.44765202
127MAPK100.44078491
128RPS6KA50.43251141
129SIK20.42833641
130MAPKAPK20.41874587
131CHEK20.41827289
132RPS6KA60.41754630
133EIF2AK20.41079325
134CAMK40.40944961
135NEK60.40832262

Predicted pathways (KEGG)

RankGene SetZ-score
1NF-kappa B signaling pathway_Homo sapiens_hsa040642.41218834
2Osteoclast differentiation_Homo sapiens_hsa043802.05497124
3Primary immunodeficiency_Homo sapiens_hsa053402.01324139
4B cell receptor signaling pathway_Homo sapiens_hsa046621.92524798
5NOD-like receptor signaling pathway_Homo sapiens_hsa046211.87203412
6Leishmaniasis_Homo sapiens_hsa051401.85672257
7Measles_Homo sapiens_hsa051621.80708832
8Intestinal immune network for IgA production_Homo sapiens_hsa046721.62812247
9Toll-like receptor signaling pathway_Homo sapiens_hsa046201.59991808
10Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.59509651
11Transcriptional misregulation in cancer_Homo sapiens_hsa052021.58364534
12Hematopoietic cell lineage_Homo sapiens_hsa046401.53755735
13Toxoplasmosis_Homo sapiens_hsa051451.52992557
14TNF signaling pathway_Homo sapiens_hsa046681.51742542
15Antigen processing and presentation_Homo sapiens_hsa046121.50817010
16Herpes simplex infection_Homo sapiens_hsa051681.50685020
17Chronic myeloid leukemia_Homo sapiens_hsa052201.48625075
18T cell receptor signaling pathway_Homo sapiens_hsa046601.46841562
19Influenza A_Homo sapiens_hsa051641.45681401
20Graft-versus-host disease_Homo sapiens_hsa053321.40766087
21RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.40224668
22Small cell lung cancer_Homo sapiens_hsa052221.37420965
23Jak-STAT signaling pathway_Homo sapiens_hsa046301.36867714
24Hepatitis B_Homo sapiens_hsa051611.32018217
25Prostate cancer_Homo sapiens_hsa052151.28574147
26Acute myeloid leukemia_Homo sapiens_hsa052211.25981503
27Legionellosis_Homo sapiens_hsa051341.23840239
28Pancreatic cancer_Homo sapiens_hsa052121.19043452
29Lysine degradation_Homo sapiens_hsa003101.18385918
30Apoptosis_Homo sapiens_hsa042101.16566667
31Renal cell carcinoma_Homo sapiens_hsa052111.14949671
32MicroRNAs in cancer_Homo sapiens_hsa052061.13836990
33Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.13490999
34Viral carcinogenesis_Homo sapiens_hsa052031.12559967
35Allograft rejection_Homo sapiens_hsa053301.11036204
36Non-homologous end-joining_Homo sapiens_hsa034501.09367448
37Malaria_Homo sapiens_hsa051441.08235695
38Tuberculosis_Homo sapiens_hsa051521.04684043
39HTLV-I infection_Homo sapiens_hsa051661.04614234
40Chemokine signaling pathway_Homo sapiens_hsa040621.04112224
41FoxO signaling pathway_Homo sapiens_hsa040681.03706390
42Fanconi anemia pathway_Homo sapiens_hsa034601.03615786
43AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.03280741
44Choline metabolism in cancer_Homo sapiens_hsa052311.02232304
45Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.99826211
46Type II diabetes mellitus_Homo sapiens_hsa049300.99038878
47ErbB signaling pathway_Homo sapiens_hsa040120.97801565
48Pertussis_Homo sapiens_hsa051330.96259784
49Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.96238126
50Systemic lupus erythematosus_Homo sapiens_hsa053220.95682165
51VEGF signaling pathway_Homo sapiens_hsa043700.95018583
52Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.94538987
53Adherens junction_Homo sapiens_hsa045200.94182387
54Leukocyte transendothelial migration_Homo sapiens_hsa046700.93887976
55Phosphatidylinositol signaling system_Homo sapiens_hsa040700.93292828
56Prolactin signaling pathway_Homo sapiens_hsa049170.91192920
57Insulin resistance_Homo sapiens_hsa049310.90441162
58Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.89550693
59Colorectal cancer_Homo sapiens_hsa052100.88915558
60Hepatitis C_Homo sapiens_hsa051600.88156773
61Dorso-ventral axis formation_Homo sapiens_hsa043200.87950071
62Estrogen signaling pathway_Homo sapiens_hsa049150.87012562
63Inositol phosphate metabolism_Homo sapiens_hsa005620.86500456
64Viral myocarditis_Homo sapiens_hsa054160.85050481
65Non-small cell lung cancer_Homo sapiens_hsa052230.83846539
66Endometrial cancer_Homo sapiens_hsa052130.83540144
67Platelet activation_Homo sapiens_hsa046110.83233471
68Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.82290756
69* mRNA surveillance pathway_Homo sapiens_hsa030150.81447560
70Thyroid hormone signaling pathway_Homo sapiens_hsa049190.81206289
71Sphingolipid signaling pathway_Homo sapiens_hsa040710.79412043
72Type I diabetes mellitus_Homo sapiens_hsa049400.79090694
73Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.78610964
74Carbohydrate digestion and absorption_Homo sapiens_hsa049730.77807090
75mTOR signaling pathway_Homo sapiens_hsa041500.77257706
76Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.77191823
77Neurotrophin signaling pathway_Homo sapiens_hsa047220.76002059
78Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.75066204
79Phospholipase D signaling pathway_Homo sapiens_hsa040720.74411889
80Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.72176279
81African trypanosomiasis_Homo sapiens_hsa051430.71570841
82Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.71304884
83Asthma_Homo sapiens_hsa053100.70331382
84Proteoglycans in cancer_Homo sapiens_hsa052050.70249818
85Epstein-Barr virus infection_Homo sapiens_hsa051690.69897062
86Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.69784686
87Staphylococcus aureus infection_Homo sapiens_hsa051500.69627035
88Notch signaling pathway_Homo sapiens_hsa043300.69336154
89GnRH signaling pathway_Homo sapiens_hsa049120.69019137
90ABC transporters_Homo sapiens_hsa020100.68483051
91TGF-beta signaling pathway_Homo sapiens_hsa043500.67932206
92RNA degradation_Homo sapiens_hsa030180.67419623
93Autoimmune thyroid disease_Homo sapiens_hsa053200.67034847
94Adipocytokine signaling pathway_Homo sapiens_hsa049200.66568712
95Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.65251777
96Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.65227030
97Focal adhesion_Homo sapiens_hsa045100.64007157
98p53 signaling pathway_Homo sapiens_hsa041150.63852489
99Pathways in cancer_Homo sapiens_hsa052000.63792314
100Long-term potentiation_Homo sapiens_hsa047200.63469579
101Cell cycle_Homo sapiens_hsa041100.62624980
102Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.60961799
103MAPK signaling pathway_Homo sapiens_hsa040100.60457884
104Thyroid cancer_Homo sapiens_hsa052160.60200346
105Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.60027407
106Alcoholism_Homo sapiens_hsa050340.58233629
107Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.57101922
108Rheumatoid arthritis_Homo sapiens_hsa053230.56497469
109Salmonella infection_Homo sapiens_hsa051320.56202775
110Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.55658172
111Longevity regulating pathway - mammal_Homo sapiens_hsa042110.52854096
112Shigellosis_Homo sapiens_hsa051310.52704447
113PI3K-Akt signaling pathway_Homo sapiens_hsa041510.49531016
114Glioma_Homo sapiens_hsa052140.49425658
115Circadian rhythm_Homo sapiens_hsa047100.48983567
116Amoebiasis_Homo sapiens_hsa051460.48432716
117Long-term depression_Homo sapiens_hsa047300.47658304
118Melanoma_Homo sapiens_hsa052180.47607211
119Taste transduction_Homo sapiens_hsa047420.45927927
120Sphingolipid metabolism_Homo sapiens_hsa006000.45314392
121Insulin signaling pathway_Homo sapiens_hsa049100.44056966

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