PCGF5

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1antigen processing and presentation of endogenous peptide antigen (GO:0002483)4.58268627
2antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)4.58268627
3negative regulation of cell killing (GO:0031342)4.50011510
4negative regulation of leukocyte mediated cytotoxicity (GO:0001911)4.50011510
5antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G4.34122350
6antigen processing and presentation of endogenous antigen (GO:0019883)4.22875350
7regulation of RIG-I signaling pathway (GO:0039535)4.09956003
8NIK/NF-kappaB signaling (GO:0038061)3.81288483
9regulation of B cell receptor signaling pathway (GO:0050855)3.75868183
10ribosomal small subunit assembly (GO:0000028)3.75004187
11regulation of platelet aggregation (GO:0090330)3.44125284
12DNA deamination (GO:0045006)3.44050840
13positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.36906226
14regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway (GO:0039531)3.36183106
15regulation of T-helper 1 cell differentiation (GO:0045625)3.33339339
16type I interferon signaling pathway (GO:0060337)3.31595866
17cellular response to type I interferon (GO:0071357)3.31595866
18positive regulation of natural killer cell differentiation (GO:0032825)3.29254721
19natural killer cell mediated cytotoxicity (GO:0042267)3.28719196
20natural killer cell mediated immunity (GO:0002228)3.28719196
21response to type I interferon (GO:0034340)3.27666404
22positive regulation of granulocyte differentiation (GO:0030854)3.21795236
23modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.21282990
24modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.21282990
25positive regulation by organism of defense response of other organism involved in symbiotic interact3.21282990
26modulation by symbiont of host immune response (GO:0052553)3.21282990
27positive regulation by symbiont of host defense response (GO:0052509)3.21282990
28modulation by symbiont of host defense response (GO:0052031)3.21282990
29regulation of gamma-delta T cell activation (GO:0046643)3.20138165
30antigen processing and presentation via MHC class Ib (GO:0002475)3.15946274
31telomere maintenance via semi-conservative replication (GO:0032201)3.14207427
32DNA strand elongation involved in DNA replication (GO:0006271)3.11443330
33macrophage activation involved in immune response (GO:0002281)3.09957625
34immunoglobulin mediated immune response (GO:0016064)3.08640388
35response to interferon-alpha (GO:0035455)3.07155256
36DNA replication initiation (GO:0006270)3.04278115
37myeloid dendritic cell activation (GO:0001773)3.04079874
38neutrophil activation involved in immune response (GO:0002283)3.03117705
39negative regulation of viral genome replication (GO:0045071)3.00225998
40positive regulation of type I interferon-mediated signaling pathway (GO:0060340)3.00092275
41positive regulation of interferon-alpha production (GO:0032727)2.99426491
42response to interleukin-15 (GO:0070672)2.99282877
43myeloid dendritic cell differentiation (GO:0043011)2.98359742
44DNA strand elongation (GO:0022616)2.98154110
45telomere maintenance via recombination (GO:0000722)2.98079164
46DNA replication checkpoint (GO:0000076)2.97508933
47regulation of gamma-delta T cell differentiation (GO:0045586)2.96547601
48B cell receptor signaling pathway (GO:0050853)2.96232262
49positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)2.95982880
50response to interferon-beta (GO:0035456)2.95932714
51meiotic chromosome segregation (GO:0045132)2.95106344
52purine nucleobase biosynthetic process (GO:0009113)2.94594255
53detection of molecule of bacterial origin (GO:0032490)2.94485540
54negative regulation of T-helper cell differentiation (GO:0045623)2.88029876
55negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)2.88029876
56detection of other organism (GO:0098543)2.85749613
57positive regulation of mast cell activation (GO:0033005)2.84717218
58regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)2.84673794
59protein localization to kinetochore (GO:0034501)2.84661667
60positive regulation of cellular amide metabolic process (GO:0034250)2.81306250
61cellular response to interferon-beta (GO:0035458)2.80093379
62regulation of interferon-alpha production (GO:0032647)2.79570370
63hepatocyte apoptotic process (GO:0097284)2.79040025
64negative regulation of interleukin-12 production (GO:0032695)2.78950859
65negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)2.77663726
66negative T cell selection (GO:0043383)2.76047436
67nucleobase biosynthetic process (GO:0046112)2.75612023
68negative regulation of T cell mediated immunity (GO:0002710)2.74775563
69microglial cell activation (GO:0001774)2.74575105
70negative regulation of lymphocyte mediated immunity (GO:0002707)2.73712470
71cellular extravasation (GO:0045123)2.73499385
72mitotic recombination (GO:0006312)2.72685538
73B cell mediated immunity (GO:0019724)2.70860725
74negative thymic T cell selection (GO:0045060)2.70835916
75granulocyte activation (GO:0036230)2.70139793
76germinal center formation (GO:0002467)2.70098410
77regulation of T-helper 2 cell differentiation (GO:0045628)2.69867155
78regulation of response to interferon-gamma (GO:0060330)2.68627929
79T cell migration (GO:0072678)2.67756059
80positive regulation of protein import into nucleus, translocation (GO:0033160)2.67587067
81maturation of SSU-rRNA (GO:0030490)2.66502289
82protein localization to chromosome, centromeric region (GO:0071459)2.66097203
83detection of external biotic stimulus (GO:0098581)2.65454119
84necroptotic process (GO:0070266)2.65244686
85detection of bacterium (GO:0016045)2.64792551
86positive regulation of macrophage differentiation (GO:0045651)2.64633385
87positive regulation of gamma-delta T cell activation (GO:0046645)2.62485224
88regulation of regulatory T cell differentiation (GO:0045589)2.62282492
89mitotic metaphase plate congression (GO:0007080)2.60836565
90Arp2/3 complex-mediated actin nucleation (GO:0034314)2.59759162
91regulation of type I interferon-mediated signaling pathway (GO:0060338)2.59272626
92regulation of platelet activation (GO:0010543)2.58299497
93myeloid cell activation involved in immune response (GO:0002275)2.57937623
94negative regulation of erythrocyte differentiation (GO:0045647)2.57880667
95response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.57158280
96response to host immune response (GO:0052572)2.57158280
97cellular response to interleukin-15 (GO:0071350)2.57005281
98megakaryocyte development (GO:0035855)2.56444849
99endosome to pigment granule transport (GO:0043485)2.56043946
100endosome to melanosome transport (GO:0035646)2.56043946
101lipopolysaccharide-mediated signaling pathway (GO:0031663)2.55412012
102defense response to protozoan (GO:0042832)2.55118413
103cellular response to exogenous dsRNA (GO:0071360)2.54712208
104positive regulation of B cell differentiation (GO:0045579)2.54169527
105positive regulation of interferon-beta production (GO:0032728)2.53096577
106dendritic cell differentiation (GO:0097028)2.52457980
107deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.51839211
108regulation of interferon-beta biosynthetic process (GO:0045357)2.51367602
109CENP-A containing nucleosome assembly (GO:0034080)2.51261713
110leukocyte mediated cytotoxicity (GO:0001909)2.51017996
111regulation of interleukin-12 biosynthetic process (GO:0045075)2.49242068
112regulation of interferon-gamma-mediated signaling pathway (GO:0060334)2.47058947
113chromatin remodeling at centromere (GO:0031055)2.46420675
114response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.46329698
115response to host (GO:0075136)2.46329698
116response to host defenses (GO:0052200)2.46329698
117regulation of natural killer cell activation (GO:0032814)2.46313152
118interferon-gamma-mediated signaling pathway (GO:0060333)2.45643329
119regulation of natural killer cell differentiation (GO:0032823)2.45456440
120positive regulation of receptor recycling (GO:0001921)2.44924476
121positive regulation of natural killer cell activation (GO:0032816)2.44721694
122macrophage activation (GO:0042116)2.44095105
123regulation of natural killer cell mediated immunity (GO:0002715)2.43227628
124regulation of natural killer cell mediated cytotoxicity (GO:0042269)2.43227628
125positive regulation of defense response to virus by host (GO:0002230)2.42632330
126positive regulation of type 2 immune response (GO:0002830)2.41811849
127negative regulation of leukocyte mediated immunity (GO:0002704)2.41301446
128cellular response to zinc ion (GO:0071294)2.40577794
129T-helper 1 type immune response (GO:0042088)2.39722854
130antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)2.39418072
131regulation of defense response to virus by host (GO:0050691)2.39125550
132positive regulation of immunoglobulin mediated immune response (GO:0002891)2.38376511
133positive regulation of B cell mediated immunity (GO:0002714)2.38376511
134regulation of mast cell degranulation (GO:0043304)2.38335550
135DNA synthesis involved in DNA repair (GO:0000731)2.37359294
136positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.37192487
137metaphase plate congression (GO:0051310)2.37060289
138regulation of antigen processing and presentation of peptide antigen (GO:0002583)2.36992873
139protein K6-linked ubiquitination (GO:0085020)2.36902423
140thrombin receptor signaling pathway (GO:0070493)2.36894454
141attachment of spindle microtubules to kinetochore (GO:0008608)2.36812330
142positive regulation of alpha-beta T cell proliferation (GO:0046641)2.36744388
143tolerance induction (GO:0002507)2.34864448
144mitotic nuclear envelope disassembly (GO:0007077)2.34775726
145positive regulation of Rap GTPase activity (GO:0032854)2.34404414
146response to protozoan (GO:0001562)2.34097243
147regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.33938977
148neutrophil activation (GO:0042119)2.33847518
149antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:2.33674866
150chaperone mediated protein folding requiring cofactor (GO:0051085)2.33275714
151ribosome biogenesis (GO:0042254)2.32229257
152positive regulation of toll-like receptor signaling pathway (GO:0034123)2.31672594
153regulation of necroptotic process (GO:0060544)2.31483220
154negative regulation of interleukin-17 production (GO:0032700)2.31378901
155leukocyte migration involved in inflammatory response (GO:0002523)2.31198330
156regulation of T cell mediated cytotoxicity (GO:0001914)2.30895906
157positive regulation of antigen processing and presentation (GO:0002579)2.30415172
158regulation of double-strand break repair via homologous recombination (GO:0010569)2.30364804
159positive T cell selection (GO:0043368)2.30313722
160telomere maintenance via telomere lengthening (GO:0010833)2.30072509
161regulation of T cell tolerance induction (GO:0002664)2.29988839
162natural killer cell differentiation (GO:0001779)2.29446696
163T cell selection (GO:0045058)2.29403519
164response to peptidoglycan (GO:0032494)2.28952703
165DNA replication-independent nucleosome organization (GO:0034724)2.28701309
166DNA replication-independent nucleosome assembly (GO:0006336)2.28701309
167nucleotide-excision repair, DNA gap filling (GO:0006297)2.28195610
168cellular response to ethanol (GO:0071361)2.27873852
169positive thymic T cell selection (GO:0045059)2.27773048
170regulation of mast cell activation (GO:0033003)2.27474515
171regulation of antigen receptor-mediated signaling pathway (GO:0050854)2.27340860
172cellular response to thyroid hormone stimulus (GO:0097067)2.26501771
173regulation of alpha-beta T cell proliferation (GO:0046640)2.26188835
174piRNA metabolic process (GO:0034587)2.26043552
175T cell apoptotic process (GO:0070231)2.25273139
176formation of translation preinitiation complex (GO:0001731)2.24920068
177positive regulation of type I interferon production (GO:0032481)2.24901168
178negative regulation of adaptive immune response based on somatic recombination of immune receptors b2.23846096
179translesion synthesis (GO:0019985)2.23820726
180dendritic cell chemotaxis (GO:0002407)2.23735821
181positive regulation of blood coagulation (GO:0030194)2.23313860

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human6.74036385
2IRF8_22096565_ChIP-ChIP_GC-B_Human4.22045341
3SMAD_19615063_ChIP-ChIP_OVARY_Human3.30098906
4* IRF8_22096565_ChIP-ChIP_GC-B_Mouse3.23771747
5IRF8_21731497_ChIP-ChIP_J774_Mouse3.10400880
6EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.76990547
7* IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.73667055
8MYC_18555785_ChIP-Seq_MESCs_Mouse2.65595669
9RUNX_20019798_ChIP-Seq_JUKART_Human2.65459366
10Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse2.64335381
11E2F4_17652178_ChIP-ChIP_JURKAT_Human2.43608013
12SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.35676913
13EGR1_19374776_ChIP-ChIP_THP-1_Human2.33173315
14NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.28225567
15GABP_17652178_ChIP-ChIP_JURKAT_Human2.27196545
16SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.25441602
17FOXM1_23109430_ChIP-Seq_U2OS_Human2.11372947
18EST1_17652178_ChIP-ChIP_JURKAT_Human2.10683678
19MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.10462431
20KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.05305876
21VDR_23849224_ChIP-Seq_CD4+_Human2.03988521
22FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.02472717
23* MYB_21317192_ChIP-Seq_ERMYB_Mouse2.02449160
24GATA1_19941826_ChIP-Seq_K562_Human2.00808075
25CREB1_15753290_ChIP-ChIP_HEK293T_Human2.00411039
26SPI1_23127762_ChIP-Seq_K562_Human1.99985044
27ELF1_17652178_ChIP-ChIP_JURKAT_Human1.99338851
28E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.98300597
29JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.96897701
30SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.91826901
31* STAT4_19710469_ChIP-ChIP_TH1__Mouse1.91061967
32GATA2_21666600_ChIP-Seq_HMVEC_Human1.90929126
33FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.88647349
34SPI1_23547873_ChIP-Seq_NB4_Human1.85286785
35GATA1_22025678_ChIP-Seq_K562_Human1.85012429
36MYC_18358816_ChIP-ChIP_MESCs_Mouse1.84402642
37TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.83568942
38FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.80158772
39ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.79972055
40ETS1_20019798_ChIP-Seq_JURKAT_Human1.79656035
41MYC_19030024_ChIP-ChIP_MESCs_Mouse1.77530237
42SCL_19346495_ChIP-Seq_HPC-7_Human1.71169231
43GATA2_19941826_ChIP-Seq_K562_Human1.70961869
44HOXB4_20404135_ChIP-ChIP_EML_Mouse1.70535309
45LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.69526719
46TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.68600980
47FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.68522141
48GATA1_19941827_ChIP-Seq_MEL_Mouse1.68395208
49SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.67606752
50E2F1_21310950_ChIP-Seq_MCF-7_Human1.66709818
51* IRF8_27001747_Chip-Seq_BMDM_Mouse1.66260326
52MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.66196077
53CDX2_19796622_ChIP-Seq_MESCs_Mouse1.65399040
54DCP1A_22483619_ChIP-Seq_HELA_Human1.64979896
55AR_21909140_ChIP-Seq_LNCAP_Human1.64538856
56NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.62949309
57ERG_20887958_ChIP-Seq_HPC-7_Mouse1.62677711
58NELFA_20434984_ChIP-Seq_ESCs_Mouse1.60666201
59FOXP3_21729870_ChIP-Seq_TREG_Human1.60300183
60* GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.59849868
61MYC_22102868_ChIP-Seq_BL_Human1.59747962
62* NOTCH1_21737748_ChIP-Seq_TLL_Human1.58282897
63PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.57547003
64SRF_21415370_ChIP-Seq_HL-1_Mouse1.55848269
65STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.55520951
66MYB_26560356_Chip-Seq_TH2_Human1.55348133
67MYC_19079543_ChIP-ChIP_MESCs_Mouse1.54930600
68VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.50432740
69RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.50249479
70* E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.48452495
71VDR_24787735_ChIP-Seq_THP-1_Human1.46280616
72FOXO3_23340844_ChIP-Seq_DLD1_Human1.46217684
73ELK1_19687146_ChIP-ChIP_HELA_Human1.45495297
74XRN2_22483619_ChIP-Seq_HELA_Human1.45278915
75SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.42216467
76STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.41291786
77GABP_19822575_ChIP-Seq_HepG2_Human1.40825957
78E2F1_18555785_ChIP-Seq_MESCs_Mouse1.40786081
79MYB_26560356_Chip-Seq_TH1_Human1.39988902
80LXR_22158963_ChIP-Seq_LIVER_Mouse1.36821985
81CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.34929963
82PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.33641665
83VDR_21846776_ChIP-Seq_THP-1_Human1.33141546
84NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.33051710
85MAF_26560356_Chip-Seq_TH1_Human1.32872796
86PU_27001747_Chip-Seq_BMDM_Mouse1.30386837
87CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.29892570
88RXR_22158963_ChIP-Seq_LIVER_Mouse1.26418144
89* TCF7_22412390_ChIP-Seq_EML_Mouse1.25202685
90RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.22936027
91NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.22710729
92MYCN_18555785_ChIP-Seq_MESCs_Mouse1.21568177
93GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.21488041
94HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.20690176
95GATA2_22383799_ChIP-Seq_G1ME_Mouse1.20663285
96RUNX1_22412390_ChIP-Seq_EML_Mouse1.20038284
97NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.16693400
98MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.16360302
99BRD4_27068464_Chip-Seq_AML-cells_Mouse1.15848725
100GATA3_26560356_Chip-Seq_TH2_Human1.15507217
101FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.14990418
102BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.12754452
103SALL4_18804426_ChIP-ChIP_XEN_Mouse1.12710457
104ZFX_18555785_ChIP-Seq_MESCs_Mouse1.11715678
105GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.11571204
106HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.11213079
107* FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.11162648
108TFEB_21752829_ChIP-Seq_HELA_Human1.10869396
109STAT3_1855785_ChIP-Seq_MESCs_Mouse1.09333139
110* STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.09311397
111CIITA_25753668_ChIP-Seq_RAJI_Human1.08428877
112CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.07887450
113NANOG_18555785_ChIP-Seq_MESCs_Mouse1.07741223
114GATA1_22383799_ChIP-Seq_G1ME_Mouse1.07687635
115MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.07452670
116PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.05567408
117SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.04457213
118ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.04159506
119TTF2_22483619_ChIP-Seq_HELA_Human1.03500345
120GATA1_19941827_ChIP-Seq_MEL86_Mouse1.03262209
121POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.03125695
122VDR_24763502_ChIP-Seq_THP-1_Human1.03097443
123ESR1_20079471_ChIP-ChIP_T-47D_Human1.02846505
124PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.02023626
125CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.99702475
126* FOXA2_19822575_ChIP-Seq_HepG2_Human0.99231920
127LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.98536559
128PPARA_22158963_ChIP-Seq_LIVER_Mouse0.98507601
129MYBL2_22936984_ChIP-ChIP_MESCs_Mouse0.98398714
130NR1I2_20693526_ChIP-Seq_LIVER_Mouse0.97860835
131* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.97196053
132GATA3_27048872_Chip-Seq_THYMUS_Human0.96043445
133TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.95870397
134BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.94651398
135* KDM2B_26808549_Chip-Seq_SUP-B15_Human0.94224299
136PPAR_26484153_Chip-Seq_NCI-H1993_Human0.94045966
137KDM2B_26808549_Chip-Seq_HPB-ALL_Human0.93556220
138UTX_26944678_Chip-Seq_JUKART_Human0.93375390
139KDM5A_27292631_Chip-Seq_BREAST_Human0.93174201
140SOX2_27498859_Chip-Seq_STOMACH_Mouse0.92639462
141BP1_19119308_ChIP-ChIP_Hs578T_Human0.92376294
142STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.91372505
143MAF_26560356_Chip-Seq_TH2_Human0.90931401
144RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.90326480
145* PU.1_20513432_ChIP-Seq_Bcells_Mouse0.90043059
146CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.89950825
147EGR1_23403033_ChIP-Seq_LIVER_Mouse0.88259291
148NRF2_20460467_ChIP-Seq_MEFs_Mouse0.87779066
149NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.87779066
150ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.85954544
151ZNF217_24962896_ChIP-Seq_MCF-7_Human0.85741935
152KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse0.82142271
153SMRT_27268052_Chip-Seq_Bcells_Human0.80008829
154THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.79582155
155SOX2_20726797_ChIP-Seq_SW620_Human0.79415244
156TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse0.79337641
157* FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.78855335
158JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.78365484
159CTNNB1_20460455_ChIP-Seq_HCT116_Human0.77474304
160JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.77391731
161GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.76130616
162KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.75219862

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001835_abnormal_antigen_presentation4.00898394
2MP0009785_altered_susceptibility_to3.17436021
3MP0000685_abnormal_immune_system3.10213363
4MP0003693_abnormal_embryo_hatching2.97376485
5MP0005671_abnormal_response_to2.83794901
6MP0003300_gastrointestinal_ulcer2.81616126
7MP0002396_abnormal_hematopoietic_system2.70337683
8MP0010094_abnormal_chromosome_stability2.62826852
9MP0002148_abnormal_hypersensitivity_rea2.57297548
10MP0008057_abnormal_DNA_replication2.56394888
11MP0008004_abnormal_stomach_pH2.42475741
12MP0003436_decreased_susceptibility_to2.36051474
13MP0005025_abnormal_response_to2.30811117
14MP0005000_abnormal_immune_tolerance2.24832487
15MP0001800_abnormal_humoral_immune2.20974462
16MP0003763_abnormal_thymus_physiology2.20633776
17MP0003656_abnormal_erythrocyte_physiolo2.19772192
18MP0001790_abnormal_immune_system2.19186949
19MP0005387_immune_system_phenotype2.19186949
20MP0002166_altered_tumor_susceptibility2.17498657
21MP0004510_myositis2.12177029
22MP0002452_abnormal_antigen_presenting2.11095562
23MP0003077_abnormal_cell_cycle2.10124999
24MP0002723_abnormal_immune_serum2.09319425
25MP0004957_abnormal_blastocyst_morpholog2.02856195
26MP0002398_abnormal_bone_marrow2.02203833
27MP0001819_abnormal_immune_cell2.00963451
28MP0002420_abnormal_adaptive_immunity1.99228470
29MP0009333_abnormal_splenocyte_physiolog1.97333575
30MP0002006_tumorigenesis1.97126308
31MP0001853_heart_inflammation1.95310059
32MP0001545_abnormal_hematopoietic_system1.94283486
33MP0005397_hematopoietic_system_phenotyp1.94283486
34MP0008007_abnormal_cellular_replicative1.93078687
35MP0008058_abnormal_DNA_repair1.91134781
36MP0002419_abnormal_innate_immunity1.89788034
37MP0004808_abnormal_hematopoietic_stem1.88602137
38MP0003111_abnormal_nucleus_morphology1.87988232
39MP0003183_abnormal_peptide_metabolism1.84427852
40MP0000716_abnormal_immune_system1.81749799
41MP0008877_abnormal_DNA_methylation1.74161607
42MP0003724_increased_susceptibility_to1.67504988
43MP0002429_abnormal_blood_cell1.62102981
44MP0000689_abnormal_spleen_morphology1.61280344
45MP0010307_abnormal_tumor_latency1.58989760
46MP0002722_abnormal_immune_system1.57015956
47MP0002405_respiratory_system_inflammati1.56813541
48MP0005464_abnormal_platelet_physiology1.52608393
49MP0002139_abnormal_hepatobiliary_system1.51108310
50MP0010155_abnormal_intestine_physiology1.50513440
51MP0003646_muscle_fatigue1.49721811
52MP0002877_abnormal_melanocyte_morpholog1.44193487
53MP0003186_abnormal_redox_activity1.38276727
54MP0000490_abnormal_crypts_of1.38110898
55MP0001845_abnormal_inflammatory_respons1.37470911
56MP0006082_CNS_inflammation1.36796912
57MP0004947_skin_inflammation1.34175304
58MP0001851_eye_inflammation1.33279000
59MP0002998_abnormal_bone_remodeling1.32938813
60MP0005310_abnormal_salivary_gland1.31024719
61MP0003075_altered_response_to1.29014528
62MP0008469_abnormal_protein_level1.28795858
63MP0000858_altered_metastatic_potential1.27714270
64MP0003091_abnormal_cell_migration1.25962193
65MP0008260_abnormal_autophagy1.25954344
66MP0000703_abnormal_thymus_morphology1.25547258
67MP0002019_abnormal_tumor_incidence1.22328187
68MP0003690_abnormal_glial_cell1.22109073
69MP0003252_abnormal_bile_duct1.19474917
70MP0003045_fibrosis1.17844791
71MP0009840_abnormal_foam_cell1.15832454
72MP0004782_abnormal_surfactant_physiolog1.15263794
73MP0004484_altered_response_of1.12606755
74MP0005166_decreased_susceptibility_to1.10812368
75MP0004130_abnormal_muscle_cell1.10422390
76MP0004883_abnormal_blood_vessel1.09840943
77MP0003448_altered_tumor_morphology1.08321391
78MP0000313_abnormal_cell_death1.07431898
79MP0005174_abnormal_tail_pigmentation1.04263396
80MP0003221_abnormal_cardiomyocyte_apopto1.03685324
81MP0003786_premature_aging1.02068218
82MP0005164_abnormal_response_to1.01682835
83MP0000249_abnormal_blood_vessel1.00847013
84MP0002332_abnormal_exercise_endurance1.00521496
85MP0004036_abnormal_muscle_relaxation1.00509533
86MP0003566_abnormal_cell_adhesion0.99927595
87MP0010352_gastrointestinal_tract_polyps0.99821601
88MP0004381_abnormal_hair_follicle0.98920278
89MP0002138_abnormal_hepatobiliary_system0.98699444
90MP0001873_stomach_inflammation0.97453706
91MP0000350_abnormal_cell_proliferation0.96952443
92MP0001533_abnormal_skeleton_physiology0.95998417
93MP0009764_decreased_sensitivity_to0.95657524
94MP0005365_abnormal_bile_salt0.95072343
95MP0010329_abnormal_lipoprotein_level0.93921565
96MP0002163_abnormal_gland_morphology0.92956820
97MP0003172_abnormal_lysosome_physiology0.92890089
98MP0003866_abnormal_defecation0.92409742
99MP0004084_abnormal_cardiac_muscle0.91644554
100MP0005058_abnormal_lysosome_morphology0.88226034
101MP0001348_abnormal_lacrimal_gland0.88169089
102MP0000343_altered_response_to0.87889360
103MP0006054_spinal_hemorrhage0.87340073
104MP0005167_abnormal_blood-brain_barrier0.86563992
105MP0008874_decreased_physiological_sensi0.86178096
106MP0009278_abnormal_bone_marrow0.86016401
107MP0005165_increased_susceptibility_to0.85363126
108MP0003828_pulmonary_edema0.83514402
109MP0005085_abnormal_gallbladder_physiolo0.81852311
110MP0003453_abnormal_keratinocyte_physiol0.81391099
111MP0003303_peritoneal_inflammation0.81175682
112MP0000604_amyloidosis0.80871979
113MP0006036_abnormal_mitochondrial_physio0.79427862
114MP0009763_increased_sensitivity_to0.78467204
115MP0001765_abnormal_ion_homeostasis0.78211579
116MP0001764_abnormal_homeostasis0.76942338
117MP0000609_abnormal_liver_physiology0.75157898
118MP0001730_embryonic_growth_arrest0.74796425
119MP0002210_abnormal_sex_determination0.74434023
120MP0001663_abnormal_digestive_system0.74427375
121MP0001929_abnormal_gametogenesis0.74397941
122MP0002009_preneoplasia0.73734659
123MP0002277_abnormal_respiratory_mucosa0.73701689
124MP0008932_abnormal_embryonic_tissue0.72841915
125MP0003191_abnormal_cellular_cholesterol0.72481432
126MP0003879_abnormal_hair_cell0.71619172
127MP0005666_abnormal_adipose_tissue0.71385592
128MP0005023_abnormal_wound_healing0.70818801
129MP0002132_abnormal_respiratory_system0.69349409
130MP0000465_gastrointestinal_hemorrhage0.68383763
131MP0005451_abnormal_body_composition0.67710353
132MP0005075_abnormal_melanosome_morpholog0.66653287
133MP0003943_abnormal_hepatobiliary_system0.66220240
134MP0005621_abnormal_cell_physiology0.64732948
135MP0003984_embryonic_growth_retardation0.64350705
136MP0001119_abnormal_female_reproductive0.62147926
137MP0000358_abnormal_cell_content/0.61652842
138MP0002088_abnormal_embryonic_growth/wei0.60687057

Predicted human phenotypes

RankGene SetZ-score
1Prolonged bleeding time (HP:0003010)5.17090560
2Thrombocytosis (HP:0001894)4.46085143
3Gingival bleeding (HP:0000225)4.31545903
4Menorrhagia (HP:0000132)4.05645934
5Abnormal platelet volume (HP:0011876)3.99866791
6Purpura (HP:0000979)3.98771904
7Increased mean platelet volume (HP:0011877)3.89926132
8Chronic otitis media (HP:0000389)3.86557368
9Elevated erythrocyte sedimentation rate (HP:0003565)3.84901716
10Recurrent bacterial skin infections (HP:0005406)3.82174737
11Recurrent abscess formation (HP:0002722)3.79857551
12Spontaneous hematomas (HP:0007420)3.63622669
13Recurrent viral infections (HP:0004429)3.53366312
14Myositis (HP:0100614)3.52069670
15Eczematoid dermatitis (HP:0000976)3.46981502
16Recurrent fungal infections (HP:0002841)3.33739121
17Birth length less than 3rd percentile (HP:0003561)3.18110152
18Stomatitis (HP:0010280)3.14839138
19Aplastic anemia (HP:0001915)3.12201820
20Recurrent bronchitis (HP:0002837)3.08711813
21Increased IgM level (HP:0003496)3.03683869
22Nasal polyposis (HP:0100582)2.96184093
23Autoimmune thrombocytopenia (HP:0001973)2.91706431
24IgM deficiency (HP:0002850)2.81266436
25Abnormal number of erythroid precursors (HP:0012131)2.80182327
26Mediastinal lymphadenopathy (HP:0100721)2.79534651
27Abnormality of the common coagulation pathway (HP:0010990)2.77291344
28IgG deficiency (HP:0004315)2.77043700
29Abnormal spermatogenesis (HP:0008669)2.76989722
30Abnormality of macrophages (HP:0004311)2.75328269
31Acute myeloid leukemia (HP:0004808)2.75306754
32Abnormality of cells of the erythroid lineage (HP:0012130)2.70343912
33Acanthocytosis (HP:0001927)2.70019363
34Abnormality of T cell physiology (HP:0011840)2.69833010
35Hypergammaglobulinemia (HP:0010702)2.68865906
36Amaurosis fugax (HP:0100576)2.68167949
37Poikilocytosis (HP:0004447)2.66254212
38Petechiae (HP:0000967)2.63120422
39Abnormality of the nasal mucosa (HP:0000433)2.62957617
40Basal ganglia calcification (HP:0002135)2.62674462
41Recurrent skin infections (HP:0001581)2.60431787
42Chromsome breakage (HP:0040012)2.58883778
43Vasculitis (HP:0002633)2.57058707
44Reticulocytopenia (HP:0001896)2.56724810
45Joint swelling (HP:0001386)2.54794017
46Abnormality of T cells (HP:0002843)2.52330884
47Orchitis (HP:0100796)2.52172162
48Abnormal platelet function (HP:0011869)2.51322626
49Impaired platelet aggregation (HP:0003540)2.51322626
50Retrobulbar optic neuritis (HP:0100654)2.50510851
51Optic neuritis (HP:0100653)2.50510851
52Panhypogammaglobulinemia (HP:0003139)2.50430255
53Hyperlipoproteinemia (HP:0010980)2.50081816
54Granulocytopenia (HP:0001913)2.47989964
55Reduced antithrombin III activity (HP:0001976)2.46389365
56Eosinophilia (HP:0001880)2.46180507
57Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.45088939
58Abnormal delayed hypersensitivity skin test (HP:0002963)2.43958678
59B lymphocytopenia (HP:0010976)2.40280664
60Abnormality of B cell number (HP:0010975)2.40280664
61Chromosomal breakage induced by crosslinking agents (HP:0003221)2.37910560
62Arterial thrombosis (HP:0004420)2.37376149
63Gastrointestinal infarctions (HP:0005244)2.37328293
64Lymphoma (HP:0002665)2.37128541
65Type I transferrin isoform profile (HP:0003642)2.36727181
66Keratoconjunctivitis sicca (HP:0001097)2.36266038
67Abnormality of the prostate (HP:0008775)2.35824813
68Pulmonary infiltrates (HP:0002113)2.35616641
69Recurrent cutaneous fungal infections (HP:0011370)2.35188864
70Chronic mucocutaneous candidiasis (HP:0002728)2.35188864
71Hypoplasia of the thymus (HP:0000778)2.35068296
72Chest pain (HP:0100749)2.34948460
73Azoospermia (HP:0000027)2.33924415
74Episodic fever (HP:0001954)2.30656975
75Myelodysplasia (HP:0002863)2.30580659
76Polycythemia (HP:0001901)2.30210049
77Pulmonary embolism (HP:0002204)2.28367117
78Entropion (HP:0000621)2.27476184
79Inflammation of the large intestine (HP:0002037)2.27451008
80IgA deficiency (HP:0002720)2.26085180
81Poikiloderma (HP:0001029)2.23226297
82Dysostosis multiplex (HP:0000943)2.21904781
83Recurrent gram-negative bacterial infections (HP:0005420)2.21664301
84Abnormality of the anterior horn cell (HP:0006802)2.21572550
85Degeneration of anterior horn cells (HP:0002398)2.21572550
86Leukocytosis (HP:0001974)2.19636442
87Abnormality of eosinophils (HP:0001879)2.19579652
88Abnormality of T cell number (HP:0011839)2.17671289
89Oral leukoplakia (HP:0002745)2.17439830
90Gingivitis (HP:0000230)2.17046084
91Elevated circulating parathyroid hormone (PTH) level (HP:0003165)2.15891407
92Obstructive lung disease (HP:0006536)2.15850514
93Chronic obstructive pulmonary disease (HP:0006510)2.15850514
94Abnormality of chromosome stability (HP:0003220)2.15089979
95Autoimmune hemolytic anemia (HP:0001890)2.13983649
96Gastrointestinal inflammation (HP:0004386)2.13046433
97Abnormality of the vasculature of the conjunctiva (HP:0008054)2.12911716
98Periodontitis (HP:0000704)2.12697571
99Abnormality of the preputium (HP:0100587)2.12271059
100Colitis (HP:0002583)2.12122285
101Keratoconjunctivitis (HP:0001096)2.10523574
102Conjunctival telangiectasia (HP:0000524)2.10061959
103Meningitis (HP:0001287)2.09418323
104Encephalitis (HP:0002383)2.09391651
105Chronic diarrhea (HP:0002028)2.06733369
106Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.06544523
107Decreased activity of mitochondrial respiratory chain (HP:0008972)2.06544523
108Interstitial pulmonary disease (HP:0006530)2.05517565
109Papilledema (HP:0001085)2.04745561
110Exertional dyspnea (HP:0002875)2.04723870
111Osteomyelitis (HP:0002754)2.03875221
112Breast hypoplasia (HP:0003187)2.03415744
113Cellulitis (HP:0100658)2.03412676
114Abnormality of cells of the lymphoid lineage (HP:0012140)2.02885194
115Albinism (HP:0001022)2.02841815
116Pancytopenia (HP:0001876)2.02584844
117Neutropenia (HP:0001875)2.01919144
118T lymphocytopenia (HP:0005403)2.01273394
119Lymphopenia (HP:0001888)2.01104888
120Increased IgE level (HP:0003212)2.00569876
121Abnormality of liposaccharide metabolism (HP:0010968)2.00449024
122Abnormality of glycosphingolipid metabolism (HP:0004343)2.00449024
123Abnormality of glycolipid metabolism (HP:0010969)2.00449024
124Hemoptysis (HP:0002105)1.99894961
125Cleft eyelid (HP:0000625)1.98948737
126Slow saccadic eye movements (HP:0000514)1.98743033
127Abnormality of iron homeostasis (HP:0011031)1.98390117
128Pulmonary fibrosis (HP:0002206)1.97756239
129Acute hepatic failure (HP:0006554)1.97670955
130Muscle fiber atrophy (HP:0100295)1.97334253
131Bruising susceptibility (HP:0000978)1.96977796
132Hypochromic microcytic anemia (HP:0004840)1.95880935
133Gastrointestinal stroma tumor (HP:0100723)1.95497735
13411 pairs of ribs (HP:0000878)1.95120939
135Mitral stenosis (HP:0001718)1.94480265
136Joint hemorrhage (HP:0005261)1.93808295
137Epistaxis (HP:0000421)1.93232741
138Gangrene (HP:0100758)1.92542801
139Fatigue (HP:0012378)1.92280429
140Type 2 muscle fiber atrophy (HP:0003554)1.91551625
141Clubbing of toes (HP:0100760)1.91489983
142Papillary thyroid carcinoma (HP:0002895)1.91185907
143Myocardial infarction (HP:0001658)1.91076122
144Pustule (HP:0200039)1.91075436
145Poor head control (HP:0002421)1.90157193
146Pallor (HP:0000980)1.89602190
147Subaortic stenosis (HP:0001682)1.89488359
148Abnormality of the left ventricular outflow tract (HP:0011103)1.89488359
149Bone marrow hypocellularity (HP:0005528)1.89361885
150Bronchitis (HP:0012387)1.88310266
151Leukopenia (HP:0001882)1.85959419
152Urticaria (HP:0001025)1.84721418
153Microcytic anemia (HP:0001935)1.83382156
154Thrombophlebitis (HP:0004418)1.82915142
155Vertigo (HP:0002321)1.81644277
156Arthralgia (HP:0002829)1.79096506
157Hematochezia (HP:0002573)1.78568683
158Peritonitis (HP:0002586)1.78431177
159Glomerulopathy (HP:0100820)1.77233734
160Hyporeflexia of lower limbs (HP:0002600)1.77112023
161Testicular neoplasm (HP:0010788)1.77060629

Predicted kinase interactions (KEA)

RankGene SetZ-score
1WEE13.21829636
2JAK33.02780908
3ACVR1B2.95983298
4MAP3K142.81843754
5NME22.80865370
6TYK22.78616521
7BMPR22.70637291
8PRPF4B2.52808775
9KIT2.34105313
10PIM22.23792273
11MAP4K12.17491248
12NEK22.16825962
13TBK12.16372223
14FGFR32.15466187
15FLT32.05722531
16BRSK22.05283861
17IRAK42.05227727
18IKBKB1.97893633
19RPS6KA41.88677678
20NEK91.84434157
21IKBKE1.83932784
22IRAK31.71776125
23EIF2AK11.67832799
24CDC71.66094311
25CSK1.64218673
26PLK41.63234738
27PIK3CG1.62256380
28TEC1.59757901
29VRK11.55300936
30BUB11.52799180
31TXK1.52766779
32BTK1.48644151
33MAP3K21.48594448
34CHUK1.45735638
35STK41.42499081
36GRK61.41141755
37MAP3K31.36981652
38ERN11.36058014
39PIM11.33325531
40EIF2AK31.32839121
41FES1.32373612
42ZAP701.32246241
43KSR21.28279454
44PBK1.23558455
45PDK11.23183224
46MAP3K11.22256073
47CDK41.20416019
48JAK11.17983423
49NLK1.17530966
50FGR1.16139170
51DYRK31.14753316
52STK241.14683517
53SRPK11.13669116
54CSF1R1.11118893
55PDK41.08854363
56PDK31.08854363
57ATR1.08524550
58TAOK21.08195804
59IRAK11.07760639
60EIF2AK21.06171101
61MAP3K131.05862371
62MYLK1.05632812
63ZAK1.05465269
64TGFBR11.04969380
65PDPK11.04209534
66STK161.04072079
67MST41.01789208
68SGK31.00490262
69SYK1.00041149
70TSSK60.94805972
71PLK10.94733899
72STK30.94487393
73AURKB0.94255094
74BMX0.91871641
75SIK30.91490953
76EPHB10.89787140
77SCYL20.88714141
78CDK70.88292807
79PTK2B0.87369224
80RPS6KB20.86092423
81MAPK120.85879652
82WNK10.85830535
83TAOK10.85688658
84SGK20.85204742
85HIPK20.84784407
86BRSK10.82791748
87RAF10.82611929
88CCNB10.80369278
89RIPK10.78953746
90IRAK20.78864834
91CDC42BPA0.76963843
92TNK20.76371772
93CDK80.75122357
94STK380.74821534
95RET0.72022597
96EPHA30.71919495
97ABL20.70444514
98FGFR40.70297161
99YES10.70070540
100LRRK20.70011329
101MAP2K30.69477302
102BLK0.69222654
103LCK0.68160674
104STK100.67530066
105MAPK110.66847445
106MARK20.65951949
107TAOK30.65629878
108MUSK0.65459733
109TTN0.65187637
110CAMKK10.63570569
111OBSCN0.62439188
112CHEK20.61862158
113BCKDK0.61756199
114MAPK70.60033520
115TGFBR20.59639163
116PASK0.59175596
117LYN0.58511034
118PKN20.57797856
119TRPM70.56940946
120MAP3K120.56608738
121MAP3K110.56349870
122MAP3K70.55724764
123PRKCQ0.53622442
124KDR0.52774254
125MAP3K50.52723540
126RIPK40.51935349
127MARK30.51520028
128GRK70.50910726
129GRK50.50843509
130MELK0.50811882
131PDGFRB0.50788072
132CHEK10.50690793
133MAP3K80.50601885
134JAK20.48373884
135AKT30.48020086
136EEF2K0.47184800
137DAPK20.47051100
138HCK0.46556850
139NUAK10.45900482
140FYN0.45685286
141MKNK10.45600498
142MATK0.45203904
143CDK120.45136152
144FRK0.45027896
145RPS6KA50.44514456
146NEK10.44081733
147CAMKK20.44057353
148CDK60.43699382
149MKNK20.43562229
150PDK20.43408217
151ITK0.41166706
152ATM0.39632321
153MAPKAPK20.37743413
154ILK0.33589784

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030303.63567235
2Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.99554442
3Mismatch repair_Homo sapiens_hsa034302.64013701
4Allograft rejection_Homo sapiens_hsa053302.44607820
5Proteasome_Homo sapiens_hsa030502.36174060
6Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.33835306
7Base excision repair_Homo sapiens_hsa034102.33114098
8Homologous recombination_Homo sapiens_hsa034402.32960175
9RNA polymerase_Homo sapiens_hsa030202.24033136
10Intestinal immune network for IgA production_Homo sapiens_hsa046722.13452669
11Herpes simplex infection_Homo sapiens_hsa051682.08683059
12Ribosome_Homo sapiens_hsa030102.08378799
13Measles_Homo sapiens_hsa051622.07589105
14NF-kappa B signaling pathway_Homo sapiens_hsa040642.05238493
15RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.97776249
16Antigen processing and presentation_Homo sapiens_hsa046121.93357507
17Primary immunodeficiency_Homo sapiens_hsa053401.89745327
18Pyrimidine metabolism_Homo sapiens_hsa002401.86558548
19Leishmaniasis_Homo sapiens_hsa051401.82424240
20Nucleotide excision repair_Homo sapiens_hsa034201.81888557
21Cell cycle_Homo sapiens_hsa041101.76955231
22Legionellosis_Homo sapiens_hsa051341.71661453
23Graft-versus-host disease_Homo sapiens_hsa053321.67503248
24RNA transport_Homo sapiens_hsa030131.64139182
25Influenza A_Homo sapiens_hsa051641.59035729
26p53 signaling pathway_Homo sapiens_hsa041151.57115831
27Fanconi anemia pathway_Homo sapiens_hsa034601.55363917
28NOD-like receptor signaling pathway_Homo sapiens_hsa046211.54476394
29Spliceosome_Homo sapiens_hsa030401.50773294
30Basal transcription factors_Homo sapiens_hsa030221.46301815
31Toll-like receptor signaling pathway_Homo sapiens_hsa046201.44967342
32Type I diabetes mellitus_Homo sapiens_hsa049401.43398248
33One carbon pool by folate_Homo sapiens_hsa006701.39095600
34Non-small cell lung cancer_Homo sapiens_hsa052231.37950307
35Pentose phosphate pathway_Homo sapiens_hsa000301.34819690
36Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.31895541
37RNA degradation_Homo sapiens_hsa030181.29596741
38Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.28105561
39Pancreatic cancer_Homo sapiens_hsa052121.27422338
40Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.27386881
41Jak-STAT signaling pathway_Homo sapiens_hsa046301.27312205
42Non-homologous end-joining_Homo sapiens_hsa034501.26616698
43Autoimmune thyroid disease_Homo sapiens_hsa053201.25590289
44Asthma_Homo sapiens_hsa053101.23690655
45Epstein-Barr virus infection_Homo sapiens_hsa051691.21841719
46Phosphatidylinositol signaling system_Homo sapiens_hsa040701.11206538
47Toxoplasmosis_Homo sapiens_hsa051451.08879966
48Apoptosis_Homo sapiens_hsa042101.07346018
49Caffeine metabolism_Homo sapiens_hsa002321.00063281
50Osteoclast differentiation_Homo sapiens_hsa043800.99687863
51Chronic myeloid leukemia_Homo sapiens_hsa052200.98103457
52AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.97160507
53Renal cell carcinoma_Homo sapiens_hsa052110.96244957
54Viral myocarditis_Homo sapiens_hsa054160.95340143
55TNF signaling pathway_Homo sapiens_hsa046680.94324580
56VEGF signaling pathway_Homo sapiens_hsa043700.94305108
57Hepatitis B_Homo sapiens_hsa051610.94180995
58SNARE interactions in vesicular transport_Homo sapiens_hsa041300.94042105
59Purine metabolism_Homo sapiens_hsa002300.93540618
60Hematopoietic cell lineage_Homo sapiens_hsa046400.92484377
61Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.91341175
62Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.87808023
63Dorso-ventral axis formation_Homo sapiens_hsa043200.87753822
64Complement and coagulation cascades_Homo sapiens_hsa046100.87313727
65Endometrial cancer_Homo sapiens_hsa052130.87070052
66Inositol phosphate metabolism_Homo sapiens_hsa005620.86227339
67Shigellosis_Homo sapiens_hsa051310.85843990
68Insulin resistance_Homo sapiens_hsa049310.85352296
69Pertussis_Homo sapiens_hsa051330.85119128
70FoxO signaling pathway_Homo sapiens_hsa040680.84626433
71Acute myeloid leukemia_Homo sapiens_hsa052210.83945088
72Long-term potentiation_Homo sapiens_hsa047200.83618935
73Neurotrophin signaling pathway_Homo sapiens_hsa047220.81540165
74B cell receptor signaling pathway_Homo sapiens_hsa046620.81248980
75Viral carcinogenesis_Homo sapiens_hsa052030.81010406
76Carbohydrate digestion and absorption_Homo sapiens_hsa049730.80628538
77Protein export_Homo sapiens_hsa030600.79326559
78mTOR signaling pathway_Homo sapiens_hsa041500.78649695
79Sphingolipid signaling pathway_Homo sapiens_hsa040710.77918887
80Folate biosynthesis_Homo sapiens_hsa007900.77294290
81Tuberculosis_Homo sapiens_hsa051520.77177361
82Phagosome_Homo sapiens_hsa041450.75426999
83Glioma_Homo sapiens_hsa052140.74182835
84Choline metabolism in cancer_Homo sapiens_hsa052310.73868503
85Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.72792844
86Phospholipase D signaling pathway_Homo sapiens_hsa040720.72673454
87Small cell lung cancer_Homo sapiens_hsa052220.72619390
88Malaria_Homo sapiens_hsa051440.71131572
89Amoebiasis_Homo sapiens_hsa051460.69515166
90Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.68248169
91Type II diabetes mellitus_Homo sapiens_hsa049300.67640703
92Rheumatoid arthritis_Homo sapiens_hsa053230.67313186
93HTLV-I infection_Homo sapiens_hsa051660.66518765
94Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.65694877
95Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.65509305
96Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.65385338
97Endocytosis_Homo sapiens_hsa041440.65064222
98GnRH signaling pathway_Homo sapiens_hsa049120.64761924
99Lysosome_Homo sapiens_hsa041420.63380435
100Glycosaminoglycan degradation_Homo sapiens_hsa005310.63206227
101Vitamin B6 metabolism_Homo sapiens_hsa007500.62697687
102Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.62322159
103Transcriptional misregulation in cancer_Homo sapiens_hsa052020.61293681
104Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.60819647
105Vascular smooth muscle contraction_Homo sapiens_hsa042700.59293966
106Renin secretion_Homo sapiens_hsa049240.58957723
107Systemic lupus erythematosus_Homo sapiens_hsa053220.58091629
108Renin-angiotensin system_Homo sapiens_hsa046140.57535644
109Thyroid cancer_Homo sapiens_hsa052160.56708792
110Pancreatic secretion_Homo sapiens_hsa049720.55290473
111Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.54401187
112Cysteine and methionine metabolism_Homo sapiens_hsa002700.53892627
113Circadian rhythm_Homo sapiens_hsa047100.53503532
114Thyroid hormone signaling pathway_Homo sapiens_hsa049190.53276559
115Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.51549435
116Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.51321730
117Insulin signaling pathway_Homo sapiens_hsa049100.50467040
118Hepatitis C_Homo sapiens_hsa051600.50181524
119Prostate cancer_Homo sapiens_hsa052150.49721052
120Focal adhesion_Homo sapiens_hsa045100.49487095
121Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.49154435
122ErbB signaling pathway_Homo sapiens_hsa040120.48945287
123ABC transporters_Homo sapiens_hsa020100.48710675
124Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.48558501
125Drug metabolism - other enzymes_Homo sapiens_hsa009830.47109888
126Chemokine signaling pathway_Homo sapiens_hsa040620.46781256
127Regulation of actin cytoskeleton_Homo sapiens_hsa048100.45352149
128Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.43330855
129HIF-1 signaling pathway_Homo sapiens_hsa040660.42979020
130T cell receptor signaling pathway_Homo sapiens_hsa046600.42875521
131Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.42152070
132Salmonella infection_Homo sapiens_hsa051320.42014271
133Selenocompound metabolism_Homo sapiens_hsa004500.41691420
134Prolactin signaling pathway_Homo sapiens_hsa049170.40813109
135Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.40784299
136Galactose metabolism_Homo sapiens_hsa000520.40694661
137mRNA surveillance pathway_Homo sapiens_hsa030150.35922243
138African trypanosomiasis_Homo sapiens_hsa051430.33513123
139Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.32389520
140N-Glycan biosynthesis_Homo sapiens_hsa005100.31776562
141Other glycan degradation_Homo sapiens_hsa005110.31685518
142Fructose and mannose metabolism_Homo sapiens_hsa000510.31131815
143Adipocytokine signaling pathway_Homo sapiens_hsa049200.30838485
144Sulfur relay system_Homo sapiens_hsa041220.30630624
145Biosynthesis of amino acids_Homo sapiens_hsa012300.27590381
146Platelet activation_Homo sapiens_hsa046110.26999363
147Carbon metabolism_Homo sapiens_hsa012000.26978634
148Leukocyte transendothelial migration_Homo sapiens_hsa046700.24691551
149Staphylococcus aureus infection_Homo sapiens_hsa051500.24473020

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