PCNA

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA unwinding involved in DNA replication (GO:0006268)6.12976927
2* DNA strand elongation involved in DNA replication (GO:0006271)5.90514219
3DNA replication initiation (GO:0006270)5.62383536
4* DNA strand elongation (GO:0022616)5.60104935
5* telomere maintenance via semi-conservative replication (GO:0032201)5.42458748
6* telomere maintenance via recombination (GO:0000722)4.86313877
7DNA replication checkpoint (GO:0000076)4.76556411
8* mitotic recombination (GO:0006312)4.72915505
9protein localization to kinetochore (GO:0034501)4.69169422
10ribosomal small subunit assembly (GO:0000028)4.33836225
11DNA replication-dependent nucleosome assembly (GO:0006335)4.22359148
12DNA replication-dependent nucleosome organization (GO:0034723)4.22359148
13CENP-A containing nucleosome assembly (GO:0034080)4.18084730
14chromatin remodeling at centromere (GO:0031055)4.13674577
15* telomere maintenance via telomere lengthening (GO:0010833)4.12853564
16protein localization to chromosome, centromeric region (GO:0071459)4.10105762
17* nucleotide-excision repair, DNA gap filling (GO:0006297)4.09589529
18* regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)4.03955990
19viral transcription (GO:0019083)3.99860186
20translational termination (GO:0006415)3.93996485
21folic acid-containing compound biosynthetic process (GO:0009396)3.92771113
22DNA replication-independent nucleosome organization (GO:0034724)3.92581059
23DNA replication-independent nucleosome assembly (GO:0006336)3.92581059
24mitotic chromosome condensation (GO:0007076)3.91816157
25kinetochore organization (GO:0051383)3.74272444
26maturation of SSU-rRNA (GO:0030490)3.70217018
27mitotic nuclear envelope disassembly (GO:0007077)3.69435417
28nucleobase biosynthetic process (GO:0046112)3.64864467
29chromosome condensation (GO:0030261)3.64510609
30DNA duplex unwinding (GO:0032508)3.62272044
31DNA geometric change (GO:0032392)3.62228315
32IMP biosynthetic process (GO:0006188)3.60177743
33attachment of spindle microtubules to kinetochore (GO:0008608)3.58978058
34nuclear pore organization (GO:0006999)3.58422605
35deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.56980144
36DNA ligation (GO:0006266)3.55993705
37translational elongation (GO:0006414)3.54867172
38formation of translation preinitiation complex (GO:0001731)3.53463516
39mitotic metaphase plate congression (GO:0007080)3.52714316
40regulation of chromosome segregation (GO:0051983)3.49765887
41ribosomal small subunit biogenesis (GO:0042274)3.48554222
42pore complex assembly (GO:0046931)3.46054211
43DNA deamination (GO:0045006)3.42388217
44histone exchange (GO:0043486)3.42335907
45nuclear pore complex assembly (GO:0051292)3.42308901
46mitotic sister chromatid cohesion (GO:0007064)3.42095521
47mitotic sister chromatid segregation (GO:0000070)3.41773245
48membrane disassembly (GO:0030397)3.41501783
49nuclear envelope disassembly (GO:0051081)3.41501783
50establishment of viral latency (GO:0019043)3.40521924
51nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.38344682
52translational initiation (GO:0006413)3.38331743
53sister chromatid segregation (GO:0000819)3.35764815
54anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.33559734
55ribosome assembly (GO:0042255)3.32300180
56SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.32021068
57regulation of sister chromatid cohesion (GO:0007063)3.31976684
58negative regulation of chromosome segregation (GO:0051985)3.31781406
59regulation of centriole replication (GO:0046599)3.31421822
60positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.30777792
61positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.30777792
62positive regulation of mitotic sister chromatid separation (GO:1901970)3.30777792
63chromatin assembly or disassembly (GO:0006333)3.30479805
64purine nucleobase biosynthetic process (GO:0009113)3.29996812
65double-strand break repair via nonhomologous end joining (GO:0006303)3.29773680
66non-recombinational repair (GO:0000726)3.29773680
67regulation of spindle organization (GO:0090224)3.28550911
68negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.28453913
69regulation of mitotic metaphase/anaphase transition (GO:0030071)3.27732400
70regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.27732400
71spindle checkpoint (GO:0031577)3.27704988
72negative regulation of RNA splicing (GO:0033119)3.27472823
73establishment of integrated proviral latency (GO:0075713)3.27205762
74IMP metabolic process (GO:0046040)3.26845015
75DNA packaging (GO:0006323)3.26706844
76cotranslational protein targeting to membrane (GO:0006613)3.23460179
77protein targeting to ER (GO:0045047)3.23024184
78* telomere maintenance (GO:0000723)3.21711674
79* telomere organization (GO:0032200)3.21040509
80negative regulation of mitotic sister chromatid separation (GO:2000816)3.19885630
81negative regulation of sister chromatid segregation (GO:0033046)3.19885630
82negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.19885630
83negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.19885630
84negative regulation of mitotic sister chromatid segregation (GO:0033048)3.19885630
85metaphase plate congression (GO:0051310)3.19718794
86ribosomal large subunit biogenesis (GO:0042273)3.17638081
87regulation of mitotic sister chromatid separation (GO:0010965)3.17126748
88regulation of mitotic sister chromatid segregation (GO:0033047)3.17126748
89regulation of sister chromatid segregation (GO:0033045)3.17126748
90synapsis (GO:0007129)3.16630171
91proteasome assembly (GO:0043248)3.15927183
92meiotic chromosome segregation (GO:0045132)3.15401805
93mitotic spindle checkpoint (GO:0071174)3.12745128
94regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.12288095
95regulation of centrosome cycle (GO:0046605)3.11190080
96cellular protein complex disassembly (GO:0043624)3.10152127
97kinetochore assembly (GO:0051382)3.09579123
98viral life cycle (GO:0019058)3.08620637
99DNA conformation change (GO:0071103)3.08053783
100DNA topological change (GO:0006265)3.07669463
101establishment of protein localization to endoplasmic reticulum (GO:0072599)3.07012625
102regulation of double-strand break repair via homologous recombination (GO:0010569)3.06150522
103establishment of chromosome localization (GO:0051303)3.04121381
104mitotic G2/M transition checkpoint (GO:0044818)3.03387991
105regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.03334472
106protein localization to endoplasmic reticulum (GO:0070972)3.00390105
107regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.98805113
108ribonucleoprotein complex biogenesis (GO:0022613)2.97048470
109deoxyribonucleotide biosynthetic process (GO:0009263)2.96036173
110* cell cycle G1/S phase transition (GO:0044843)2.94861928
111* G1/S transition of mitotic cell cycle (GO:0000082)2.94861928
112maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.94452243
113regulation of histone H3-K9 methylation (GO:0051570)2.94121096
114ATP-dependent chromatin remodeling (GO:0043044)2.94024008
115somatic hypermutation of immunoglobulin genes (GO:0016446)2.92706899
116somatic diversification of immune receptors via somatic mutation (GO:0002566)2.92706899
117negative regulation of mRNA processing (GO:0050686)2.90751229
118DNA replication (GO:0006260)2.89296670
119positive regulation of chromosome segregation (GO:0051984)2.89181305
120protein complex disassembly (GO:0043241)2.86933651
121protein localization to chromosome (GO:0034502)2.86443091
122spliceosomal snRNP assembly (GO:0000387)2.85795841
123* transcription-coupled nucleotide-excision repair (GO:0006283)2.85062129
124DNA synthesis involved in DNA repair (GO:0000731)2.84979207
125* translesion synthesis (GO:0019985)2.84911904
126mRNA splicing, via spliceosome (GO:0000398)2.84425613
127RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)2.84425613
128* mitotic cell cycle (GO:0000278)2.83869737
129regulation of DNA endoreduplication (GO:0032875)2.83703316
130RNA splicing, via transesterification reactions (GO:0000375)2.83309758
131chromosome segregation (GO:0007059)2.81795869
132termination of RNA polymerase II transcription (GO:0006369)2.81627307
133rRNA processing (GO:0006364)2.81358827
134nuclear-transcribed mRNA catabolic process (GO:0000956)2.80957169

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXM1_23109430_ChIP-Seq_U2OS_Human4.43711944
2* E2F4_17652178_ChIP-ChIP_JURKAT_Human4.13027710
3* MYC_18555785_ChIP-Seq_MESCs_Mouse3.87285704
4EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.66229486
5* FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.24314924
6* MYC_19079543_ChIP-ChIP_MESCs_Mouse2.63426420
7* KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.60986326
8* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.54255505
9EST1_17652178_ChIP-ChIP_JURKAT_Human2.52794898
10* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.48045089
11EGR1_19374776_ChIP-ChIP_THP-1_Human2.39714888
12AR_21909140_ChIP-Seq_LNCAP_Human2.35985785
13GABP_17652178_ChIP-ChIP_JURKAT_Human2.34565787
14* E2F1_21310950_ChIP-Seq_MCF-7_Human2.28406105
15ETS1_20019798_ChIP-Seq_JURKAT_Human2.26066149
16* CREB1_15753290_ChIP-ChIP_HEK293T_Human2.24182346
17XRN2_22483619_ChIP-Seq_HELA_Human2.19778503
18SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.18499117
19* NELFA_20434984_ChIP-Seq_ESCs_Mouse2.17395736
20* JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.07396554
21VDR_23849224_ChIP-Seq_CD4+_Human2.05151421
22HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.04308192
23MYC_22102868_ChIP-Seq_BL_Human2.02193513
24* E2F7_22180533_ChIP-Seq_HELA_Human10.6954975
25ELF1_17652178_ChIP-ChIP_JURKAT_Human1.96392427
26* CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.93823109
27* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.92549912
28MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.87038315
29FOXP3_21729870_ChIP-Seq_TREG_Human1.83960714
30DCP1A_22483619_ChIP-Seq_HELA_Human1.80330792
31* TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.77179544
32* MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.76449601
33* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.74666103
34TTF2_22483619_ChIP-Seq_HELA_Human1.71111765
35NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.70022463
36* MYCN_18555785_ChIP-Seq_MESCs_Mouse1.68130012
37GABP_19822575_ChIP-Seq_HepG2_Human1.62237948
38ELK1_19687146_ChIP-ChIP_HELA_Human1.58051476
39HOXB4_20404135_ChIP-ChIP_EML_Mouse1.56995107
40PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.56847590
41CIITA_25753668_ChIP-Seq_RAJI_Human1.55135119
42ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.50606711
43VDR_21846776_ChIP-Seq_THP-1_Human1.50376474
44KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.50082151
45FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.48700016
46THAP11_20581084_ChIP-Seq_MESCs_Mouse1.46771412
47* SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.46501796
48ZFX_18555785_ChIP-Seq_MESCs_Mouse1.46290291
49POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.45918225
50MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.45477863
51ERG_20887958_ChIP-Seq_HPC-7_Mouse1.40653117
52SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.39154003
53* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.38399230
54KDM5A_27292631_Chip-Seq_BREAST_Human1.36003293
55NANOG_18555785_ChIP-Seq_MESCs_Mouse1.34649140
56PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.29356613
57YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.29041198
58* FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.28690763
59E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.26554471
60ESR1_15608294_ChIP-ChIP_MCF-7_Human1.23186829
61* CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.23049057
62ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.21271678
63SPI1_23547873_ChIP-Seq_NB4_Human1.18764999
64TFEB_21752829_ChIP-Seq_HELA_Human1.16797817
65FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.16434568
66IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.13180082
67* KLF4_18555785_ChIP-Seq_MESCs_Mouse1.09018579
68PADI4_21655091_ChIP-ChIP_MCF-7_Human1.08544062
69GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.08206091
70YY1_21170310_ChIP-Seq_MESCs_Mouse1.07845684
71MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.07072287
72SRF_21415370_ChIP-Seq_HL-1_Mouse1.06174813
73DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.04587096
74CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.03294169
75CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.01563713
76MYB_21317192_ChIP-Seq_ERMYB_Mouse1.00210597
77POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.98775659
78ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.96505873
79TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse0.96262584
80TP63_19390658_ChIP-ChIP_HaCaT_Human0.96128368
81STAT3_1855785_ChIP-Seq_MESCs_Mouse0.96116996
82MYB_26560356_Chip-Seq_TH2_Human0.95910982
83MYC_18940864_ChIP-ChIP_HL60_Human0.95747282
84SALL1_21062744_ChIP-ChIP_HESCs_Human0.95334064
85CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.91328805
86SCL_19346495_ChIP-Seq_HPC-7_Human0.90999182
87SOX17_20123909_ChIP-Seq_XEN_Mouse0.90484379
88* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.90160091
89NOTCH1_21737748_ChIP-Seq_TLL_Human0.90016797
90* KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.89903214
91SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.89403736
92SOX2_18555785_ChIP-Seq_MESCs_Mouse0.89086180
93TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.88984599
94* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.88613120
95MAF_26560356_Chip-Seq_TH1_Human0.88457579
96* POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.87454635
97HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.87338088
98MYB_26560356_Chip-Seq_TH1_Human0.87183561
99* NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.86893907
100KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.86765698
101KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.86765698
102KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.86765698
103UTX_26944678_Chip-Seq_JUKART_Human0.86611542
104E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse0.85814955
105SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.85595581
106* STAT4_19710469_ChIP-ChIP_TH1__Mouse0.85332297
107HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.83656556
108IRF8_21731497_ChIP-ChIP_J774_Mouse0.82458681
109ZNF263_19887448_ChIP-Seq_K562_Human0.81559997
110RUNX1_22412390_ChIP-Seq_EML_Mouse0.81252236
111* PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.80965212
112GATA1_22383799_ChIP-Seq_G1ME_Mouse0.80748138
113HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.80587398
114* NANOG_16153702_ChIP-ChIP_HESCs_Human0.80330089
115* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.78813383
116BRD4_27068464_Chip-Seq_AML-cells_Mouse0.78758537
117TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.78270165
118CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.78096599
119DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.76964653
120* BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.72635776
121CHD1_26751641_Chip-Seq_LNCaP_Human0.71024691

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010094_abnormal_chromosome_stability5.00107522
2MP0003693_abnormal_embryo_hatching4.68621031
3MP0008057_abnormal_DNA_replication4.14309623
4MP0003111_abnormal_nucleus_morphology4.12851671
5MP0004957_abnormal_blastocyst_morpholog3.99372269
6MP0003077_abnormal_cell_cycle3.84494980
7MP0008058_abnormal_DNA_repair2.97728752
8MP0002396_abnormal_hematopoietic_system2.91922750
9MP0008007_abnormal_cellular_replicative2.69789832
10MP0008932_abnormal_embryonic_tissue2.43374641
11MP0010307_abnormal_tumor_latency2.36130684
12MP0010352_gastrointestinal_tract_polyps2.33176780
13MP0000350_abnormal_cell_proliferation2.18584427
14MP0001730_embryonic_growth_arrest2.10529755
15MP0006292_abnormal_olfactory_placode2.08557034
16MP0000490_abnormal_crypts_of2.07507623
17MP0004808_abnormal_hematopoietic_stem2.05048404
18MP0009697_abnormal_copulation2.03385544
19MP0008877_abnormal_DNA_methylation1.94452253
20MP0003941_abnormal_skin_development1.86350999
21MP0001545_abnormal_hematopoietic_system1.81195442
22MP0005397_hematopoietic_system_phenotyp1.81195442
23MP0009333_abnormal_splenocyte_physiolog1.78195154
24MP0003763_abnormal_thymus_physiology1.77185282
25* MP0002398_abnormal_bone_marrow1.68724209
26MP0002019_abnormal_tumor_incidence1.66600473
27MP0003123_paternal_imprinting1.62698992
28MP0006054_spinal_hemorrhage1.61889721
29MP0000703_abnormal_thymus_morphology1.59384334
30MP0010234_abnormal_vibrissa_follicle1.55888814
31MP0003786_premature_aging1.54131745
32MP0003806_abnormal_nucleotide_metabolis1.52238119
33MP0000313_abnormal_cell_death1.49921643
34MP0001697_abnormal_embryo_size1.49617082
35MP0002722_abnormal_immune_system1.49439602
36MP0000689_abnormal_spleen_morphology1.46929892
37MP0009379_abnormal_foot_pigmentation1.45790824
38MP0001835_abnormal_antigen_presentation1.42530756
39MP0009278_abnormal_bone_marrow1.41795893
40MP0001672_abnormal_embryogenesis/_devel1.41509331
41MP0005380_embryogenesis_phenotype1.41509331
42* MP0002080_prenatal_lethality1.41291094
43MP0005076_abnormal_cell_differentiation1.39364764
44MP0009672_abnormal_birth_weight1.30253256
45* MP0002429_abnormal_blood_cell1.30165701
46MP0003984_embryonic_growth_retardation1.29170194
47MP0001800_abnormal_humoral_immune1.28770780
48MP0008789_abnormal_olfactory_epithelium1.26254259
49MP0002088_abnormal_embryonic_growth/wei1.25881287
50MP0000685_abnormal_immune_system1.24699394
51MP0002085_abnormal_embryonic_tissue1.23535121
52* MP0000716_abnormal_immune_system1.22384423
53MP0004197_abnormal_fetal_growth/weight/1.21317227
54MP0002086_abnormal_extraembryonic_tissu1.19375678
55MP0005501_abnormal_skin_physiology1.17549699
56MP0001346_abnormal_lacrimal_gland1.16141051
57* MP0002452_abnormal_antigen_presenting1.14923606
58* MP0002420_abnormal_adaptive_immunity1.14894258
59* MP0001819_abnormal_immune_cell1.13295471
60MP0005671_abnormal_response_to1.12585687
61MP0002084_abnormal_developmental_patter1.12218359
62MP0003699_abnormal_female_reproductive1.10849648
63MP0003567_abnormal_fetal_cardiomyocyte1.08986472
64MP0000858_altered_metastatic_potential1.07519531
65MP0005395_other_phenotype1.06956509
66MP0003656_abnormal_erythrocyte_physiolo1.06578301
67MP0002723_abnormal_immune_serum1.04034821
68MP0003436_decreased_susceptibility_to1.03776631
69MP0005394_taste/olfaction_phenotype1.02816675
70MP0005499_abnormal_olfactory_system1.02816675
71MP0006035_abnormal_mitochondrial_morpho1.02605776
72MP0002405_respiratory_system_inflammati1.01978360
73MP0003121_genomic_imprinting1.01775979
74MP0001853_heart_inflammation1.01596982
75MP0005000_abnormal_immune_tolerance1.01121324
76MP0004185_abnormal_adipocyte_glucose0.99203300
77MP0002166_altered_tumor_susceptibility0.98403257
78MP0002796_impaired_skin_barrier0.96241590
79MP0002006_tumorigenesis0.95971080
80MP0000465_gastrointestinal_hemorrhage0.95345471
81* MP0002210_abnormal_sex_determination0.92318627
82MP0002163_abnormal_gland_morphology0.91960517
83MP0004147_increased_porphyrin_level0.91622701
84MP0002697_abnormal_eye_size0.91178800
85MP0005025_abnormal_response_to0.91159883
86MP0001286_abnormal_eye_development0.90384081
87MP0003937_abnormal_limbs/digits/tail_de0.90153990
88MP0009785_altered_susceptibility_to0.89236659
89MP0000566_synostosis0.88275205
90MP0001293_anophthalmia0.87355598
91MP0005174_abnormal_tail_pigmentation0.86321925
92MP0002095_abnormal_skin_pigmentation0.85701432
93MP0003303_peritoneal_inflammation0.85576736
94MP0003448_altered_tumor_morphology0.85263464
95* MP0002161_abnormal_fertility/fecundity0.84729863
96* MP0001145_abnormal_male_reproductive0.81886696
97MP0006036_abnormal_mitochondrial_physio0.80312669
98MP0002233_abnormal_nose_morphology0.79683496
99MP0010155_abnormal_intestine_physiology0.77977224
100MP0001529_abnormal_vocalization0.77104042
101MP0002234_abnormal_pharynx_morphology0.77043866
102MP0000537_abnormal_urethra_morphology0.76502988
103MP0002111_abnormal_tail_morphology0.75999133
104MP0001915_intracranial_hemorrhage0.75671918
105MP0003698_abnormal_male_reproductive0.75098414
106MP0000477_abnormal_intestine_morphology0.73405378
107MP0003315_abnormal_perineum_morphology0.72275380
108MP0005384_cellular_phenotype0.71856255
109MP0003890_abnormal_embryonic-extraembry0.71571244
110MP0005621_abnormal_cell_physiology0.71075735
111MP0005464_abnormal_platelet_physiology0.71065124
112MP0000358_abnormal_cell_content/0.70596190
113MP0003221_abnormal_cardiomyocyte_apopto0.70391803
114MP0001881_abnormal_mammary_gland0.70221318
115MP0003186_abnormal_redox_activity0.69598759
116MP0002419_abnormal_innate_immunity0.68860037
117* MP0001929_abnormal_gametogenesis0.68560990
118MP0005387_immune_system_phenotype0.67902380
119MP0001790_abnormal_immune_system0.67902380
120MP0001873_stomach_inflammation0.67765587
121MP0003718_maternal_effect0.66691178
122MP0005389_reproductive_system_phenotype0.66029651
123* MP0000653_abnormal_sex_gland0.65826145
124MP0002148_abnormal_hypersensitivity_rea0.64119306
125MP0005023_abnormal_wound_healing0.63627038
126MP0000762_abnormal_tongue_morphology0.63397411
127MP0001119_abnormal_female_reproductive0.62913453
128MP0000428_abnormal_craniofacial_morphol0.62245352
129MP0005408_hypopigmentation0.61130639
130MP0002160_abnormal_reproductive_system0.60247141
131MP0002092_abnormal_eye_morphology0.60214471
132MP0003300_gastrointestinal_ulcer0.60082551
133MP0010030_abnormal_orbit_morphology0.59856549
134MP0002938_white_spotting0.59769057
135MP0000627_abnormal_mammary_gland0.59522602
136MP0002877_abnormal_melanocyte_morpholog0.58968822
137MP0003119_abnormal_digestive_system0.57761092
138MP0009703_decreased_birth_body0.57634351
139MP0002075_abnormal_coat/hair_pigmentati0.57377042
140MP0003861_abnormal_nervous_system0.57288479
141MP0003705_abnormal_hypodermis_morpholog0.56172874
142MP0002009_preneoplasia0.53569340
143MP0001661_extended_life_span0.53488709
144MP0000372_irregular_coat_pigmentation0.52048473
145MP0000049_abnormal_middle_ear0.49408846
146MP0003943_abnormal_hepatobiliary_system0.47122417
147MP0003950_abnormal_plasma_membrane0.45620391

Predicted human phenotypes

RankGene SetZ-score
1Birth length less than 3rd percentile (HP:0003561)5.41626840
2Reticulocytopenia (HP:0001896)4.84929900
3Abnormality of cells of the erythroid lineage (HP:0012130)4.59603660
4Abnormal number of erythroid precursors (HP:0012131)4.46906660
5Chromsome breakage (HP:0040012)4.02478503
6Chromosomal breakage induced by crosslinking agents (HP:0003221)3.75518386
7Abnormality of chromosome stability (HP:0003220)3.47619229
8Breast hypoplasia (HP:0003187)3.38734609
9Pallor (HP:0000980)3.30145700
10Agnosia (HP:0010524)3.28234077
11Colon cancer (HP:0003003)3.21759209
12Oral leukoplakia (HP:0002745)3.18691333
13Microvesicular hepatic steatosis (HP:0001414)3.10805057
14Aplastic anemia (HP:0001915)3.10595971
15Nephroblastoma (Wilms tumor) (HP:0002667)3.07337367
16Multiple enchondromatosis (HP:0005701)3.07229725
17Medulloblastoma (HP:0002885)2.99476937
18Patellar aplasia (HP:0006443)2.98216625
19Abnormality of the preputium (HP:0100587)2.97676819
20Selective tooth agenesis (HP:0001592)2.96408701
21Macrocytic anemia (HP:0001972)2.93023895
22Myelodysplasia (HP:0002863)2.92565117
23Meckel diverticulum (HP:0002245)2.91571625
24Embryonal renal neoplasm (HP:0011794)2.87143503
25Abnormality of the ileum (HP:0001549)2.79651342
26Aplasia/Hypoplasia of the patella (HP:0006498)2.75468189
27Aplasia/Hypoplasia of the uvula (HP:0010293)2.71740133
28Abnormality of the labia minora (HP:0012880)2.65782428
29IgM deficiency (HP:0002850)2.64076462
30Ependymoma (HP:0002888)2.63474881
31Thrombocytosis (HP:0001894)2.61372532
32Abnormality of the anterior horn cell (HP:0006802)2.57660784
33Degeneration of anterior horn cells (HP:0002398)2.57660784
34Duodenal stenosis (HP:0100867)2.57576959
35Small intestinal stenosis (HP:0012848)2.57576959
36Absent thumb (HP:0009777)2.56878258
37Basal cell carcinoma (HP:0002671)2.52800957
38Lymphoma (HP:0002665)2.51996260
39Bone marrow hypocellularity (HP:0005528)2.49844006
40Premature graying of hair (HP:0002216)2.44756064
41Increased nuchal translucency (HP:0010880)2.42727952
42Rhabdomyosarcoma (HP:0002859)2.40672417
43Rough bone trabeculation (HP:0100670)2.38876142
44Volvulus (HP:0002580)2.38156231
45Abnormality of the heme biosynthetic pathway (HP:0010472)2.37332905
46Microretrognathia (HP:0000308)2.36067326
47Ectopic kidney (HP:0000086)2.33085183
48Carpal bone hypoplasia (HP:0001498)2.31037522
49Atresia of the external auditory canal (HP:0000413)2.29885653
50Neoplasm of the pancreas (HP:0002894)2.28812915
51Slender long bone (HP:0003100)2.28738670
52Hypoplasia of the capital femoral epiphysis (HP:0003090)2.28623823
53Abnormality of cochlea (HP:0000375)2.27932904
54Abnormal number of incisors (HP:0011064)2.27489681
55Duplication of thumb phalanx (HP:0009942)2.26482133
56High pitched voice (HP:0001620)2.25953043
57Duplicated collecting system (HP:0000081)2.25790840
58Sloping forehead (HP:0000340)2.25636402
59Proximal placement of thumb (HP:0009623)2.23338662
60Abnormality of reticulocytes (HP:0004312)2.22809949
61Recurrent viral infections (HP:0004429)2.22731263
62Choanal atresia (HP:0000453)2.20876787
63Premature ovarian failure (HP:0008209)2.20501861
64T lymphocytopenia (HP:0005403)2.19819803
6511 pairs of ribs (HP:0000878)2.18873953
66B lymphocytopenia (HP:0010976)2.17313442
67Abnormality of B cell number (HP:0010975)2.17313442
68Facial cleft (HP:0002006)2.15622780
69Abnormality of the carotid arteries (HP:0005344)2.14380148
70Progressive external ophthalmoplegia (HP:0000590)2.14146752
71Supernumerary spleens (HP:0009799)2.12973126
72Abnormality of T cells (HP:0002843)2.12457765
73Amaurosis fugax (HP:0100576)2.12288239
74Cellular immunodeficiency (HP:0005374)2.11749329
75Microglossia (HP:0000171)2.11233650
76Tracheoesophageal fistula (HP:0002575)2.09981999
77Abnormality of glycolysis (HP:0004366)2.08543601
78Deviation of the thumb (HP:0009603)2.08483160
79Megaloblastic anemia (HP:0001889)2.08389962
80Squamous cell carcinoma (HP:0002860)2.06952696
81Progressive muscle weakness (HP:0003323)2.05157233
82Cafe-au-lait spot (HP:0000957)2.05100206
83Abnormality of the duodenum (HP:0002246)2.03957890
84Arteriovenous malformation (HP:0100026)2.03814260
85Pancytopenia (HP:0001876)2.03238929
86Prominent nose (HP:0000448)2.02897847
87Increased hepatocellular lipid droplets (HP:0006565)2.02877937
88Abnormality of the renal collecting system (HP:0004742)2.02517255
89Abnormal gallbladder physiology (HP:0012438)2.02362259
90Cholecystitis (HP:0001082)2.02362259
91Abnormality of T cell number (HP:0011839)1.99582472
92Absent radius (HP:0003974)1.99291182
93Embryonal neoplasm (HP:0002898)1.98551027
94Clubbing of toes (HP:0100760)1.97440924
95Neoplasm of the colon (HP:0100273)1.96363713
96Increased serum pyruvate (HP:0003542)1.94779632
97Abnormality of DNA repair (HP:0003254)1.94346327
98Cleft eyelid (HP:0000625)1.93987503
99Impulsivity (HP:0100710)1.93563819
100Triphalangeal thumb (HP:0001199)1.91599634
101Aplasia/Hypoplasia of the thymus (HP:0010515)1.91128431
102Aplasia/Hypoplasia of the sacrum (HP:0008517)1.90699215
103Abnormality of abdominal situs (HP:0011620)1.89564420
104Abdominal situs inversus (HP:0003363)1.89564420
105Poikiloderma (HP:0001029)1.87747419
106Abnormal lung lobation (HP:0002101)1.86315484
107Poor head control (HP:0002421)1.83845856
108Cellulitis (HP:0100658)1.82831110
109Absent forearm bone (HP:0003953)1.82529401
110Aplasia involving forearm bones (HP:0009822)1.82529401
111Abnormality of T cell physiology (HP:0011840)1.82391996
112IgG deficiency (HP:0004315)1.81672380
113Horseshoe kidney (HP:0000085)1.81519701
114Overlapping toe (HP:0001845)1.81458500
115Chronic otitis media (HP:0000389)1.81271037
116Short 4th metacarpal (HP:0010044)1.80432560
117Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.80432560
118Facial hemangioma (HP:0000329)1.79651650
119Abnormality of chromosome segregation (HP:0002916)1.79421988
120Asplenia (HP:0001746)1.78711923
121Short thumb (HP:0009778)1.78618134
122Secondary amenorrhea (HP:0000869)1.78282568
123Abnormality of methionine metabolism (HP:0010901)1.78130061
124Petechiae (HP:0000967)1.77474976
125Combined immunodeficiency (HP:0005387)1.77433085
126Neoplasm of striated muscle (HP:0009728)1.77210411
127Capillary hemangiomas (HP:0005306)1.76916245
128Acute myeloid leukemia (HP:0004808)1.75960509
129Leukopenia (HP:0001882)1.75913674
130Trismus (HP:0000211)1.75025495
131Lipid accumulation in hepatocytes (HP:0006561)1.74407940
132Abnormality of the septum pellucidum (HP:0007375)1.74085642
133Cortical dysplasia (HP:0002539)1.73017865
134Absent septum pellucidum (HP:0001331)1.72171936
135Sparse eyelashes (HP:0000653)1.70115901
136Septate vagina (HP:0001153)1.69965955
137Morphological abnormality of the inner ear (HP:0011390)1.63684641

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDC75.29417076
2WEE14.09667079
3BUB13.36239199
4VRK23.05761051
5NEK22.84594898
6EIF2AK12.66564220
7NME22.56190641
8ACVR1B2.28446968
9SMG12.11254700
10SRPK11.97986139
11VRK11.94138065
12TESK21.88173922
13TTK1.87323166
14PASK1.87256893
15EEF2K1.86074757
16TAF11.83801071
17BRSK21.83274308
18TLK11.82789306
19ATR1.82621543
20CCNB11.77747509
21RPS6KA41.75134663
22CDK71.73649120
23MAP4K11.70541366
24AURKB1.69371332
25MKNK11.69294296
26PLK11.66423401
27NEK11.65150562
28SCYL21.64912198
29MAP3K101.60979024
30TSSK61.60943071
31STK101.60935471
32DYRK31.60836733
33CDK41.60735874
34EIF2AK31.55768669
35STK41.52372100
36ARAF1.49972905
37RPS6KB21.49352870
38CDK121.47245257
39MAP3K81.43129683
40PLK41.42800491
41MAP3K91.34660245
42BRAF1.33268120
43TGFBR11.29393833
44CHEK21.23788947
45BRSK11.20227206
46STK161.13317693
47CHEK11.12325115
48LRRK21.10832930
49PIM11.10445445
50MKNK21.08310650
51PKN21.07814614
52CDK61.06647104
53CLK11.04530220
54NME11.00029598
55PLK30.98145072
56CDK80.97856766
57PIM20.97726494
58PAK40.96853953
59AURKA0.96748225
60MAP3K130.92743743
61PBK0.92326930
62BTK0.90124490
63STK240.89979736
64TRIM280.88030234
65ATM0.84761456
66NUAK10.83553287
67CDK20.78372393
68BRD40.74310198
69KIT0.73968844
70MST40.72977426
71GRK60.72798741
72FLT30.72614409
73MAP2K30.71667163
74CSF1R0.70930248
75RPS6KA50.69033997
76TEC0.68751818
77ZAP700.68732772
78MELK0.67149331
79KDR0.64657497
80PNCK0.64235557
81CSNK2A10.60710406
82CSNK2A20.60670228
83RAF10.60443766
84TESK10.60421513
85JAK30.59048429
86TYK20.56999347
87CDK10.56546438
88MAP3K110.53124370
89NEK90.51786980
90PAK10.51425121
91ALK0.51312034
92DAPK10.50458927
93STK30.48234259
94ZAK0.47305380
95BLK0.46877388
96CDK11A0.46723476
97SYK0.46066815
98PRKCI0.44953244
99CDK150.44909658
100ERBB40.43509280
101LYN0.43375520
102EIF2AK20.43287528
103CDK180.43208559
104YES10.42083160
105CDK140.41206516
106CSNK1G30.41020267
107TRIB30.40843413
108CSNK1G10.39906905
109CSNK1E0.39394889
110LATS20.39279591
111IRAK40.39270779
112CDK90.39125559
113KSR20.39008977
114MET0.38532603
115ITK0.38281616
116LCK0.35794645
117NEK60.35474674
118LATS10.33456960
119TXK0.32279376
120CDK30.32049980
121TBK10.29648467
122PRKDC0.29634886
123MAPKAPK50.29561458
124ILK0.29520647
125CDK190.29022540
126DYRK1B0.28636579
127FGFR10.28479668
128MAPKAPK20.27751363
129CSNK1A1L0.27484860
130IKBKB0.25455636
131AKT20.25036678
132RPS6KA60.23391840
133MAPK110.22363691
134MST1R0.22121587

Predicted pathways (KEGG)

RankGene SetZ-score
1* DNA replication_Homo sapiens_hsa030306.00455693
2* Mismatch repair_Homo sapiens_hsa034304.40087809
3Ribosome_Homo sapiens_hsa030103.29140561
4Homologous recombination_Homo sapiens_hsa034403.24600632
5Spliceosome_Homo sapiens_hsa030403.17423563
6* Base excision repair_Homo sapiens_hsa034103.07216246
7* Cell cycle_Homo sapiens_hsa041102.89324644
8Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.81568348
9* Nucleotide excision repair_Homo sapiens_hsa034202.80946235
10One carbon pool by folate_Homo sapiens_hsa006702.63931109
11RNA transport_Homo sapiens_hsa030132.62143553
12Proteasome_Homo sapiens_hsa030502.48764675
13Pyrimidine metabolism_Homo sapiens_hsa002402.33198727
14Non-homologous end-joining_Homo sapiens_hsa034502.31809058
15RNA polymerase_Homo sapiens_hsa030202.29923574
16Fanconi anemia pathway_Homo sapiens_hsa034602.23897642
17Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.88647257
18RNA degradation_Homo sapiens_hsa030181.66399273
19Systemic lupus erythematosus_Homo sapiens_hsa053221.64079265
20p53 signaling pathway_Homo sapiens_hsa041151.62780503
21Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.50374594
22Basal transcription factors_Homo sapiens_hsa030221.49982080
23mRNA surveillance pathway_Homo sapiens_hsa030151.46470519
24Antigen processing and presentation_Homo sapiens_hsa046121.26333889
25Herpes simplex infection_Homo sapiens_hsa051681.21003661
26Viral carcinogenesis_Homo sapiens_hsa052031.20811194
27Epstein-Barr virus infection_Homo sapiens_hsa051691.18859156
282-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.17910954
29Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.15126900
30Primary immunodeficiency_Homo sapiens_hsa053401.13631722
31Purine metabolism_Homo sapiens_hsa002301.09825744
32Pyruvate metabolism_Homo sapiens_hsa006201.09290175
33Vitamin B6 metabolism_Homo sapiens_hsa007501.07045316
34Parkinsons disease_Homo sapiens_hsa050121.04064736
35Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.02280154
36Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.92235860
37Legionellosis_Homo sapiens_hsa051340.88911190
38* HTLV-I infection_Homo sapiens_hsa051660.87837811
39Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.87409554
40Oxidative phosphorylation_Homo sapiens_hsa001900.86509115
41Fatty acid elongation_Homo sapiens_hsa000620.85635259
42Measles_Homo sapiens_hsa051620.81431389
43Small cell lung cancer_Homo sapiens_hsa052220.80964309
44Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.80575219
45Oocyte meiosis_Homo sapiens_hsa041140.76982214
46NF-kappa B signaling pathway_Homo sapiens_hsa040640.74447153
47Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.73914725
48Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.73365743
49Folate biosynthesis_Homo sapiens_hsa007900.72049963
50Apoptosis_Homo sapiens_hsa042100.71636333
51Transcriptional misregulation in cancer_Homo sapiens_hsa052020.71270144
52MicroRNAs in cancer_Homo sapiens_hsa052060.71095572
53Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.71041440
54Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.69137195
55Pentose phosphate pathway_Homo sapiens_hsa000300.68841761
56Chronic myeloid leukemia_Homo sapiens_hsa052200.67937065
57Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.66463978
58Shigellosis_Homo sapiens_hsa051310.66204994
59* Hepatitis B_Homo sapiens_hsa051610.65827018
60Hematopoietic cell lineage_Homo sapiens_hsa046400.63712727
61Steroid biosynthesis_Homo sapiens_hsa001000.63672587
62Alcoholism_Homo sapiens_hsa050340.62340728
63Leishmaniasis_Homo sapiens_hsa051400.59402243
64Thyroid cancer_Homo sapiens_hsa052160.59351411
65Protein export_Homo sapiens_hsa030600.58095310
66Cyanoamino acid metabolism_Homo sapiens_hsa004600.57665951
67Propanoate metabolism_Homo sapiens_hsa006400.57432501
68Colorectal cancer_Homo sapiens_hsa052100.54337591
69B cell receptor signaling pathway_Homo sapiens_hsa046620.53854529
70N-Glycan biosynthesis_Homo sapiens_hsa005100.53042514
71Cysteine and methionine metabolism_Homo sapiens_hsa002700.51957827
72Intestinal immune network for IgA production_Homo sapiens_hsa046720.51543890
73Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.50288165
74NOD-like receptor signaling pathway_Homo sapiens_hsa046210.48977660
75Sulfur relay system_Homo sapiens_hsa041220.47027803
76Biosynthesis of amino acids_Homo sapiens_hsa012300.46961109
77Selenocompound metabolism_Homo sapiens_hsa004500.46844370
78Influenza A_Homo sapiens_hsa051640.45461046
79Drug metabolism - other enzymes_Homo sapiens_hsa009830.45063991
80Viral myocarditis_Homo sapiens_hsa054160.45062991
81Pancreatic cancer_Homo sapiens_hsa052120.44195287
82Lysine degradation_Homo sapiens_hsa003100.43926325
83Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.43655946
84Alzheimers disease_Homo sapiens_hsa050100.43030266
85RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.42434464
86Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.40767397
87Central carbon metabolism in cancer_Homo sapiens_hsa052300.38044006
88Acute myeloid leukemia_Homo sapiens_hsa052210.37987803
89Bladder cancer_Homo sapiens_hsa052190.37827221
90Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.36780810
91Non-small cell lung cancer_Homo sapiens_hsa052230.36526643
92Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.36259332
93Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.36090044
94T cell receptor signaling pathway_Homo sapiens_hsa046600.36011259
95Metabolic pathways_Homo sapiens_hsa011000.35714777
96Asthma_Homo sapiens_hsa053100.35113698
97Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.34790111
98Glutathione metabolism_Homo sapiens_hsa004800.33972896
99Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.33562440
100Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.30762491
101Notch signaling pathway_Homo sapiens_hsa043300.30721614
102Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.30258061
103Prostate cancer_Homo sapiens_hsa052150.29469218
104Hippo signaling pathway_Homo sapiens_hsa043900.29138503
105Osteoclast differentiation_Homo sapiens_hsa043800.28934965
106Jak-STAT signaling pathway_Homo sapiens_hsa046300.28759221
107Allograft rejection_Homo sapiens_hsa053300.28709338
108Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.28045641
109Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.27010641
110Toxoplasmosis_Homo sapiens_hsa051450.26569617
111Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.26500761
112Pathways in cancer_Homo sapiens_hsa052000.25432082
113Toll-like receptor signaling pathway_Homo sapiens_hsa046200.25235608
114TGF-beta signaling pathway_Homo sapiens_hsa043500.24692669
115Wnt signaling pathway_Homo sapiens_hsa043100.24531036
116Leukocyte transendothelial migration_Homo sapiens_hsa046700.24470763
117Pertussis_Homo sapiens_hsa051330.23677202
118Fructose and mannose metabolism_Homo sapiens_hsa000510.23430638
119HIF-1 signaling pathway_Homo sapiens_hsa040660.22653841
120Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.22353432
121Malaria_Homo sapiens_hsa051440.21838382
122Basal cell carcinoma_Homo sapiens_hsa052170.20243810
123Renin-angiotensin system_Homo sapiens_hsa046140.19330075
124Graft-versus-host disease_Homo sapiens_hsa053320.19126784
125Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.18618706
126Arginine and proline metabolism_Homo sapiens_hsa003300.17861078
127Adherens junction_Homo sapiens_hsa045200.17766056
128Tuberculosis_Homo sapiens_hsa051520.17327736
129Melanoma_Homo sapiens_hsa052180.16005149
130Galactose metabolism_Homo sapiens_hsa000520.15418142
131Huntingtons disease_Homo sapiens_hsa050160.14635800
132TNF signaling pathway_Homo sapiens_hsa046680.14536351
133Vitamin digestion and absorption_Homo sapiens_hsa049770.14315879
134Fatty acid metabolism_Homo sapiens_hsa012120.14232555
135Carbon metabolism_Homo sapiens_hsa012000.13063687
136Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.08713578
137Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.08670479
138Pentose and glucuronate interconversions_Homo sapiens_hsa000400.06961976

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »