

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | antigen processing and presentation of endogenous antigen (GO:0019883) | 9.19198232 |
| 2 | negative regulation of catenin import into nucleus (GO:0035414) | 8.83073609 |
| 3 | negative regulation of granulocyte differentiation (GO:0030853) | 8.64717424 |
| 4 | mitotic nuclear envelope reassembly (GO:0007084) | 7.85548802 |
| 5 | nuclear envelope reassembly (GO:0031468) | 7.85548802 |
| 6 | peptidyl-lysine dimethylation (GO:0018027) | 7.45380228 |
| 7 | proteasome assembly (GO:0043248) | 7.31516730 |
| 8 | regulation of antigen processing and presentation (GO:0002577) | 7.17594592 |
| 9 | negative regulation of bone resorption (GO:0045779) | 7.00283654 |
| 10 | positive regulation of B cell differentiation (GO:0045579) | 6.92252256 |
| 11 | adaptation of signaling pathway (GO:0023058) | 6.55741351 |
| 12 | positive regulation of protein export from nucleus (GO:0046827) | 6.04971726 |
| 13 | T cell migration (GO:0072678) | 5.95093012 |
| 14 | platelet dense granule organization (GO:0060155) | 5.93499544 |
| 15 | negative regulation of bone remodeling (GO:0046851) | 5.92992901 |
| 16 | determination of adult lifespan (GO:0008340) | 5.84675044 |
| 17 | positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic proc | 5.64158028 |
| 18 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 5.44852673 |
| 19 | leukocyte tethering or rolling (GO:0050901) | 5.41047775 |
| 20 | negative regulation of multicellular organism growth (GO:0040015) | 5.24367593 |
| 21 | immunoglobulin mediated immune response (GO:0016064) | 5.23349272 |
| 22 | regulation of synapse maturation (GO:0090128) | 5.23306094 |
| 23 | autophagic vacuole fusion (GO:0000046) | 5.11933817 |
| 24 | regulation of monocyte differentiation (GO:0045655) | 5.01008464 |
| 25 | negative regulation of tissue remodeling (GO:0034104) | 4.99809582 |
| 26 | cell proliferation in forebrain (GO:0021846) | 4.99559587 |
| 27 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 4.82344952 |
| 28 | modulation by symbiont of host immune response (GO:0052553) | 4.82344952 |
| 29 | positive regulation by symbiont of host defense response (GO:0052509) | 4.82344952 |
| 30 | modulation by symbiont of host defense response (GO:0052031) | 4.82344952 |
| 31 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 4.82344952 |
| 32 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 4.82344952 |
| 33 | regulation of interleukin-6 biosynthetic process (GO:0045408) | 4.79486766 |
| 34 | negative regulation of B cell proliferation (GO:0030889) | 4.70080765 |
| 35 | negative regulation of osteoclast differentiation (GO:0045671) | 4.67845469 |
| 36 | macrophage activation involved in immune response (GO:0002281) | 4.65538393 |
| 37 | cerebral cortex radially oriented cell migration (GO:0021799) | 4.55153665 |
| 38 | regulation of granulocyte differentiation (GO:0030852) | 4.39237537 |
| 39 | organelle membrane fusion (GO:0090174) | 4.28008795 |
| 40 | regulation of B cell differentiation (GO:0045577) | 4.23493864 |
| 41 | activation of transmembrane receptor protein tyrosine kinase activity (GO:0007171) | 4.11598918 |
| 42 | mitochondrial calcium ion homeostasis (GO:0051560) | 3.99084043 |
| 43 | B cell mediated immunity (GO:0019724) | 3.92520050 |
| 44 | neutrophil activation involved in immune response (GO:0002283) | 3.78118015 |
| 45 | microglial cell activation (GO:0001774) | 3.73510152 |
| 46 | coronary vasculature morphogenesis (GO:0060977) | 3.69165120 |
| 47 | regulation of interferon-beta biosynthetic process (GO:0045357) | 3.65331878 |
| 48 | adrenergic receptor signaling pathway (GO:0071875) | 3.59760011 |
| 49 | brown fat cell differentiation (GO:0050873) | 3.59616775 |
| 50 | peptidyl-lysine trimethylation (GO:0018023) | 3.58840365 |
| 51 | negative regulation of systemic arterial blood pressure (GO:0003085) | 3.56513312 |
| 52 | positive regulation of erythrocyte differentiation (GO:0045648) | 3.52119342 |
| 53 | peroxisome fission (GO:0016559) | 3.50541470 |
| 54 | heterotypic cell-cell adhesion (GO:0034113) | 3.50483592 |
| 55 | TOR signaling (GO:0031929) | 3.50041067 |
| 56 | oxygen transport (GO:0015671) | 3.49581099 |
| 57 | pericardium development (GO:0060039) | 3.49291841 |
| 58 | glycerol metabolic process (GO:0006071) | 3.42333678 |
| 59 | cellular response to exogenous dsRNA (GO:0071360) | 3.37217670 |
| 60 | regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process (GO:2 | 3.35643491 |
| 61 | negative regulation of smooth muscle contraction (GO:0045986) | 3.30499447 |
| 62 | peptidyl-lysine methylation (GO:0018022) | 3.27537148 |
| 63 | regulation of catenin import into nucleus (GO:0035412) | 3.22578269 |
| 64 | multi-organism intracellular transport (GO:1902583) | 3.17824804 |
| 65 | transport of virus (GO:0046794) | 3.17824804 |
| 66 | intracellular transport of virus (GO:0075733) | 3.17824804 |
| 67 | multi-organism transport (GO:0044766) | 3.17824804 |
| 68 | multi-organism localization (GO:1902579) | 3.17824804 |
| 69 | positive regulation of chemokine biosynthetic process (GO:0045080) | 3.16057786 |
| 70 | phosphatidylinositol dephosphorylation (GO:0046856) | 3.14618262 |
| 71 | response to host immune response (GO:0052572) | 3.09848605 |
| 72 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 3.09848605 |
| 73 | positive regulation of neuroblast proliferation (GO:0002052) | 3.07735455 |
| 74 | alditol metabolic process (GO:0019400) | 3.06714360 |
| 75 | thrombin receptor signaling pathway (GO:0070493) | 3.04258454 |
| 76 | lymphocyte migration (GO:0072676) | 2.98077831 |
| 77 | male meiosis I (GO:0007141) | 2.96667476 |
| 78 | negative regulation of interleukin-6 production (GO:0032715) | 2.94023766 |
| 79 | phospholipid dephosphorylation (GO:0046839) | 2.93895171 |
| 80 | regulation of protein export from nucleus (GO:0046825) | 2.91077557 |
| 81 | signal peptide processing (GO:0006465) | 2.87989917 |
| 82 | gas transport (GO:0015669) | 2.87173986 |
| 83 | positive regulation of toll-like receptor signaling pathway (GO:0034123) | 2.82248379 |
| 84 | anterograde synaptic vesicle transport (GO:0048490) | 2.69481688 |
| 85 | cellular response to interferon-beta (GO:0035458) | 2.63080142 |
| 86 | negative regulation of B cell activation (GO:0050869) | 2.62478001 |
| 87 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 2.62253032 |
| 88 | ATP synthesis coupled proton transport (GO:0015986) | 2.62253032 |
| 89 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 2.62028988 |
| 90 | response to host (GO:0075136) | 2.62028988 |
| 91 | response to host defenses (GO:0052200) | 2.62028988 |
| 92 | response to dietary excess (GO:0002021) | 2.59619133 |
| 93 | positive regulation of interferon-gamma biosynthetic process (GO:0045078) | 2.53727161 |
| 94 | secretory granule organization (GO:0033363) | 2.53714291 |
| 95 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 17.1176136 |
| 96 | DNA strand renaturation (GO:0000733) | 16.3442675 |
| 97 | antigen processing and presentation via MHC class Ib (GO:0002475) | 15.6864618 |
| 98 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 12.4665710 |
| 99 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 11.1223052 |
| 100 | positive regulation of antigen processing and presentation (GO:0002579) | 10.0652274 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E2F7_22180533_ChIP-Seq_HELA_Human | 9.79773019 |
| 2 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 5.36881280 |
| 3 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 5.22797613 |
| 4 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 5.11386815 |
| 5 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 4.03487115 |
| 6 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.65508016 |
| 7 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.42036323 |
| 8 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 3.32462457 |
| 9 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 3.32120001 |
| 10 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 2.62072087 |
| 11 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.08530128 |
| 12 | BMI1_19503595_ChIP-Seq_MEFsC_Mouse | 1.93026827 |
| 13 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 1.87830678 |
| 14 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.59931629 |
| 15 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 1.59517156 |
| 16 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.58645270 |
| 17 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.53630683 |
| 18 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.49206058 |
| 19 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.43037998 |
| 20 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.42144809 |
| 21 | ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.37734321 |
| 22 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.37336706 |
| 23 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.36937011 |
| 24 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.36855970 |
| 25 | VDR_22108803_ChIP-Seq_LS180_Human | 1.36402486 |
| 26 | ETV1_20927104_ChIP-Seq_GIST48_Human | 1.36312019 |
| 27 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.36176232 |
| 28 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.35973755 |
| 29 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 1.35515123 |
| 30 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.33877930 |
| 31 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.33077506 |
| 32 | SOX2_18555785_Chip-Seq_ESCs_Mouse | 1.32922069 |
| 33 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 1.31637147 |
| 34 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.30335344 |
| 35 | P300_19829295_ChIP-Seq_ESCs_Human | 1.29368384 |
| 36 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.27566501 |
| 37 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 1.26373175 |
| 38 | PHF8_20622853_ChIP-Seq_HELA_Human | 1.24771010 |
| 39 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 1.24211813 |
| 40 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.23278822 |
| 41 | CBX2_22325352_ChIP-Seq_293T-Rex_Human | 1.22012023 |
| 42 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.20231001 |
| 43 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.18777835 |
| 44 | PCGF4_22325352_ChIP-Seq_293T-Rex_Human | 1.17855240 |
| 45 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.17410961 |
| 46 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.17317537 |
| 47 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.17182362 |
| 48 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.17065719 |
| 49 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.15003092 |
| 50 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 1.14468353 |
| 51 | OCT4_21477851_ChIP-Seq_ESCs_Mouse | 1.14337151 |
| 52 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.12323810 |
| 53 | P300_18555785_Chip-Seq_ESCs_Mouse | 1.11747650 |
| 54 | ZFX_18555785_Chip-Seq_ESCs_Mouse | 1.10463722 |
| 55 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.10443555 |
| 56 | RBPJ_21746931_ChIP-Seq_IB4_Human | 1.10125893 |
| 57 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.09643570 |
| 58 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.09643570 |
| 59 | CDX2_21074721_ChIP-Seq_CACO-2_Mouse | 1.08940671 |
| 60 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.08670392 |
| 61 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 1.07481804 |
| 62 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.07083945 |
| 63 | KLF4_18555785_Chip-Seq_ESCs_Mouse | 1.06346848 |
| 64 | GATA1_22025678_ChIP-Seq_K562_Human | 1.06074265 |
| 65 | SUZ12_18555785_Chip-Seq_ESCs_Mouse | 1.05781198 |
| 66 | NMYC_18555785_Chip-Seq_ESCs_Mouse | 1.04857025 |
| 67 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.04262180 |
| 68 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 1.04068057 |
| 69 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.02349208 |
| 70 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.02257720 |
| 71 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.02257720 |
| 72 | NCOR_22424771_ChIP-Seq_293T_Human | 1.01942918 |
| 73 | RUNX1_26923725_Chip-Seq_HPCs_Mouse | 1.01312323 |
| 74 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 0.99490740 |
| 75 | TP53_22573176_ChIP-Seq_HFKS_Human | 0.99144136 |
| 76 | EWS_26573619_Chip-Seq_HEK293_Human | 0.98894247 |
| 77 | ESRRB_18555785_Chip-Seq_ESCs_Mouse | 0.98747442 |
| 78 | NFYA_21822215_ChIP-Seq_K562_Human | 0.98512200 |
| 79 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 0.97930712 |
| 80 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.96503775 |
| 81 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.96503775 |
| 82 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 0.96454862 |
| 83 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.95883186 |
| 84 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.95407154 |
| 85 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.95043383 |
| 86 | OCT4_18555785_Chip-Seq_ESCs_Mouse | 0.94643664 |
| 87 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 0.93577417 |
| 88 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 0.93000551 |
| 89 | CTCF_18555785_Chip-Seq_ESCs_Mouse | 0.92860730 |
| 90 | PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 0.92600044 |
| 91 | RNF2_27304074_Chip-Seq_NSC_Mouse | 0.92474353 |
| 92 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 0.91057515 |
| 93 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 0.90997056 |
| 94 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 0.89688899 |
| 95 | EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse | 0.88856867 |
| 96 | RUNX1_27457419_Chip-Seq_LIVER_Mouse | 0.88576590 |
| 97 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 0.87574274 |
| 98 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 0.87386634 |
| 99 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.87152277 |
| 100 | SMAD1_18555785_Chip-Seq_ESCs_Mouse | 0.86293536 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005377_hearing/vestibular/ear_phenot | 8.06769100 |
| 2 | MP0003878_abnormal_ear_physiology | 8.06769100 |
| 3 | MP0002102_abnormal_ear_morphology | 6.89201066 |
| 4 | MP0001835_abnormal_antigen_presentation | 6.23977736 |
| 5 | MP0002166_altered_tumor_susceptibility | 4.42250959 |
| 6 | MP0003879_abnormal_hair_cell | 4.29709868 |
| 7 | MP0000685_abnormal_immune_system | 3.76793817 |
| 8 | MP0005671_abnormal_response_to | 3.59508314 |
| 9 | MP0002006_tumorigenesis | 3.35584774 |
| 10 | MP0001485_abnormal_pinna_reflex | 2.92593876 |
| 11 | MP0004742_abnormal_vestibular_system | 2.44368206 |
| 12 | MP0005360_urolithiasis | 2.25194773 |
| 13 | MP0002933_joint_inflammation | 2.21996802 |
| 14 | MP0001486_abnormal_startle_reflex | 2.20928283 |
| 15 | MP0000372_irregular_coat_pigmentation | 1.75835554 |
| 16 | MP0003137_abnormal_impulse_conducting | 1.56763875 |
| 17 | MP0001545_abnormal_hematopoietic_system | 1.45979260 |
| 18 | MP0005397_hematopoietic_system_phenotyp | 1.45979260 |
| 19 | MP0005464_abnormal_platelet_physiology | 1.38118542 |
| 20 | MP0001440_abnormal_grooming_behavior | 1.38043636 |
| 21 | MP0003136_yellow_coat_color | 1.37336686 |
| 22 | MP0002396_abnormal_hematopoietic_system | 1.32429774 |
| 23 | MP0004885_abnormal_endolymph | 1.32329363 |
| 24 | MP0004142_abnormal_muscle_tone | 1.26843145 |
| 25 | MP0005075_abnormal_melanosome_morpholog | 1.26274001 |
| 26 | MP0003111_abnormal_nucleus_morphology | 1.24293147 |
| 27 | MP0005387_immune_system_phenotype | 1.20071544 |
| 28 | MP0001790_abnormal_immune_system | 1.20071544 |
| 29 | MP0002332_abnormal_exercise_endurance | 1.19079727 |
| 30 | MP0002163_abnormal_gland_morphology | 1.19031254 |
| 31 | MP0001188_hyperpigmentation | 1.12927464 |
| 32 | MP0001873_stomach_inflammation | 1.01584460 |
| 33 | MP0003866_abnormal_defecation | 1.00207786 |
| 34 | MP0009250_abnormal_appendicular_skeleto | 0.99039023 |
| 35 | MP0004381_abnormal_hair_follicle | 0.97940302 |
| 36 | MP0009764_decreased_sensitivity_to | 0.93585314 |
| 37 | MP0005025_abnormal_response_to | 0.93021325 |
| 38 | MP0001986_abnormal_taste_sensitivity | 0.92122277 |
| 39 | MP0002837_dystrophic_cardiac_calcinosis | 0.91274596 |
| 40 | MP0002822_catalepsy | 0.87413435 |
| 41 | MP0002419_abnormal_innate_immunity | 0.86701668 |
| 42 | MP0006082_CNS_inflammation | 0.85390913 |
| 43 | MP0002277_abnormal_respiratory_mucosa | 0.83906064 |
| 44 | MP0005187_abnormal_penis_morphology | 0.81084540 |
| 45 | MP0002138_abnormal_hepatobiliary_system | 0.80688771 |
| 46 | MP0005551_abnormal_eye_electrophysiolog | 0.80626390 |
| 47 | MP0009046_muscle_twitch | 0.76505760 |
| 48 | MP0005084_abnormal_gallbladder_morpholo | 0.75867584 |
| 49 | MP0001800_abnormal_humoral_immune | 0.74688261 |
| 50 | MP0002272_abnormal_nervous_system | 0.74047438 |
| 51 | MP0005379_endocrine/exocrine_gland_phen | 0.73702127 |
| 52 | MP0003252_abnormal_bile_duct | 0.73140263 |
| 53 | MP0005645_abnormal_hypothalamus_physiol | 0.72680951 |
| 54 | MP0003724_increased_susceptibility_to | 0.72330498 |
| 55 | MP0002420_abnormal_adaptive_immunity | 0.71675818 |
| 56 | MP0002452_abnormal_antigen_presenting | 0.71481508 |
| 57 | MP0001819_abnormal_immune_cell | 0.71153663 |
| 58 | MP0005220_abnormal_exocrine_pancreas | 0.69766973 |
| 59 | MP0005423_abnormal_somatic_nervous | 0.67010320 |
| 60 | MP0002998_abnormal_bone_remodeling | 0.66797482 |
| 61 | MP0005275_abnormal_skin_tensile | 0.64373990 |
| 62 | MP0001963_abnormal_hearing_physiology | 0.63357039 |
| 63 | MP0000716_abnormal_immune_system | 0.62371701 |
| 64 | MP0001968_abnormal_touch/_nociception | 0.61664328 |
| 65 | MP0006072_abnormal_retinal_apoptosis | 0.61411576 |
| 66 | MP0005000_abnormal_immune_tolerance | 0.59552137 |
| 67 | MP0004808_abnormal_hematopoietic_stem | 0.59361917 |
| 68 | MP0008872_abnormal_physiological_respon | 0.57889532 |
| 69 | MP0002148_abnormal_hypersensitivity_rea | 0.57745269 |
| 70 | MP0001119_abnormal_female_reproductive | 0.54600422 |
| 71 | MP0003638_abnormal_response/metabolism_ | 0.53835336 |
| 72 | MP0002139_abnormal_hepatobiliary_system | 0.53491077 |
| 73 | MP0002928_abnormal_bile_duct | 0.52594874 |
| 74 | MP0002693_abnormal_pancreas_physiology | 0.52514724 |
| 75 | MP0003195_calcinosis | 0.52201726 |
| 76 | MP0000026_abnormal_inner_ear | 0.51320880 |
| 77 | MP0001845_abnormal_inflammatory_respons | 0.50828376 |
| 78 | MP0003011_delayed_dark_adaptation | 0.50148597 |
| 79 | MP0002723_abnormal_immune_serum | 0.48130627 |
| 80 | MP0001853_heart_inflammation | 0.47557213 |
| 81 | MP0010155_abnormal_intestine_physiology | 0.47550591 |
| 82 | MP0002067_abnormal_sensory_capabilities | 0.42438067 |
| 83 | MP0002090_abnormal_vision | 0.42222613 |
| 84 | MP0002735_abnormal_chemical_nociception | 0.41847248 |
| 85 | MP0008995_early_reproductive_senescence | 0.41116728 |
| 86 | MP0004924_abnormal_behavior | 0.40802196 |
| 87 | MP0005386_behavior/neurological_phenoty | 0.40802196 |
| 88 | MP0002572_abnormal_emotion/affect_behav | 0.40463109 |
| 89 | MP0002429_abnormal_blood_cell | 0.39915422 |
| 90 | MP0005410_abnormal_fertilization | 0.39247215 |
| 91 | MP0000230_abnormal_systemic_arterial | 0.38924969 |
| 92 | MP0008569_lethality_at_weaning | 0.36604823 |
| 93 | MP0002009_preneoplasia | 0.35121472 |
| 94 | MP0003937_abnormal_limbs/digits/tail_de | 0.35066930 |
| 95 | MP0004085_abnormal_heartbeat | 0.34162352 |
| 96 | MP0004134_abnormal_chest_morphology | 0.33676830 |
| 97 | MP0009745_abnormal_behavioral_response | 0.32023242 |
| 98 | MP0004145_abnormal_muscle_electrophysio | 0.31309289 |
| 99 | MP0000343_altered_response_to | 0.30050874 |
| 100 | MP0003183_abnormal_peptide_metabolism | 0.29877135 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Nasal polyposis (HP:0100582) | 8.97817851 |
| 2 | Elevated erythrocyte sedimentation rate (HP:0003565) | 8.41465110 |
| 3 | Chronic sinusitis (HP:0011109) | 8.15340987 |
| 4 | Large eyes (HP:0001090) | 7.70641092 |
| 5 | Abnormality of the nasal mucosa (HP:0000433) | 7.61810558 |
| 6 | Muscle fiber atrophy (HP:0100295) | 7.37602627 |
| 7 | Recurrent bronchitis (HP:0002837) | 6.58111550 |
| 8 | Shawl scrotum (HP:0000049) | 6.05432981 |
| 9 | Abnormality of the fingertips (HP:0001211) | 5.98802461 |
| 10 | Achilles tendon contracture (HP:0001771) | 5.98477202 |
| 11 | Atrioventricular block (HP:0001678) | 5.77909150 |
| 12 | Flat capital femoral epiphysis (HP:0003370) | 5.60346677 |
| 13 | Abnormality of the Achilles tendon (HP:0005109) | 5.50868947 |
| 14 | Reduced subcutaneous adipose tissue (HP:0003758) | 5.40453787 |
| 15 | Esophageal atresia (HP:0002032) | 5.03410897 |
| 16 | Basal ganglia calcification (HP:0002135) | 4.30740660 |
| 17 | Bronchitis (HP:0012387) | 4.02516369 |
| 18 | Elbow flexion contracture (HP:0002987) | 3.84513320 |
| 19 | Large earlobe (HP:0009748) | 3.79155904 |
| 20 | Heart block (HP:0012722) | 3.67117433 |
| 21 | Flexion contracture of toe (HP:0005830) | 3.56568594 |
| 22 | Joint contractures involving the joints of the feet (HP:0100492) | 3.56568594 |
| 23 | Abnormality of macular pigmentation (HP:0008002) | 3.47315110 |
| 24 | Rib fusion (HP:0000902) | 3.46122267 |
| 25 | Respiratory difficulties (HP:0002880) | 3.45000776 |
| 26 | Microcytic anemia (HP:0001935) | 3.40128062 |
| 27 | Abnormal atrioventricular conduction (HP:0005150) | 3.37223494 |
| 28 | Large for gestational age (HP:0001520) | 3.36538779 |
| 29 | Ectopia lentis (HP:0001083) | 3.33020910 |
| 30 | Overlapping toe (HP:0001845) | 3.32547547 |
| 31 | Gastrointestinal atresia (HP:0002589) | 3.24887509 |
| 32 | Patchy hypopigmentation of hair (HP:0011365) | 3.17771706 |
| 33 | Trismus (HP:0000211) | 3.17388170 |
| 34 | Midline defect of the nose (HP:0004122) | 2.95837337 |
| 35 | Prominent nose (HP:0000448) | 2.85940059 |
| 36 | Agnosia (HP:0010524) | 2.78233612 |
| 37 | Emphysema (HP:0002097) | 2.74153642 |
| 38 | Hypergammaglobulinemia (HP:0010702) | 2.73469406 |
| 39 | Erythema (HP:0010783) | 2.73336528 |
| 40 | Beaking of vertebral bodies (HP:0004568) | 2.73216233 |
| 41 | Clubbing of toes (HP:0100760) | 2.65517279 |
| 42 | Long toe (HP:0010511) | 2.61961849 |
| 43 | Hypertriglyceridemia (HP:0002155) | 2.47858510 |
| 44 | Trigonocephaly (HP:0000243) | 2.47229069 |
| 45 | Bronchiectasis (HP:0002110) | 2.46040040 |
| 46 | Deep philtrum (HP:0002002) | 2.38355346 |
| 47 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.30904507 |
| 48 | Severe visual impairment (HP:0001141) | 2.25633384 |
| 49 | Hemiplegia (HP:0002301) | 2.21145647 |
| 50 | Abnormality of the basal ganglia (HP:0002134) | 2.19882019 |
| 51 | Primitive reflexes (palmomental, snout, glabellar) (HP:0002476) | 2.19105620 |
| 52 | Abolished electroretinogram (ERG) (HP:0000550) | 2.09182980 |
| 53 | Chronic otitis media (HP:0000389) | 12.8593071 |
| 54 | Patellar aplasia (HP:0006443) | 1.99115504 |
| 55 | Primary atrial arrhythmia (HP:0001692) | 1.96356275 |
| 56 | Growth hormone deficiency (HP:0000824) | 1.91567789 |
| 57 | Vacuolated lymphocytes (HP:0001922) | 1.91279896 |
| 58 | Abnormality of chromosome segregation (HP:0002916) | 1.91175959 |
| 59 | Abnormality of the antihelix (HP:0009738) | 1.89267250 |
| 60 | Macroglossia (HP:0000158) | 1.88527433 |
| 61 | Hypoproteinemia (HP:0003075) | 1.88129908 |
| 62 | Supraventricular tachycardia (HP:0004755) | 1.86137942 |
| 63 | Axonal loss (HP:0003447) | 1.84916698 |
| 64 | Aplasia/Hypoplasia of the patella (HP:0006498) | 1.83589957 |
| 65 | Supraventricular arrhythmia (HP:0005115) | 1.80314390 |
| 66 | Increased IgM level (HP:0003496) | 1.80211006 |
| 67 | Encephalitis (HP:0002383) | 1.75967489 |
| 68 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 1.73085116 |
| 69 | Septo-optic dysplasia (HP:0100842) | 1.73079241 |
| 70 | Arthrogryposis multiplex congenita (HP:0002804) | 1.70664976 |
| 71 | Decreased central vision (HP:0007663) | 1.68669171 |
| 72 | Bone pain (HP:0002653) | 1.65073403 |
| 73 | Proximal placement of thumb (HP:0009623) | 1.64802606 |
| 74 | Blepharitis (HP:0000498) | 1.62354599 |
| 75 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 1.61471331 |
| 76 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 1.61471331 |
| 77 | Wide intermamillary distance (HP:0006610) | 1.56494150 |
| 78 | Overfolded helix (HP:0000396) | 1.52839425 |
| 79 | Acute hepatic failure (HP:0006554) | 1.50624036 |
| 80 | Anxiety (HP:0000739) | 1.50566633 |
| 81 | Disinhibition (HP:0000734) | 1.48467237 |
| 82 | Waddling gait (HP:0002515) | 1.47865827 |
| 83 | Arachnodactyly (HP:0001166) | 1.47495557 |
| 84 | Childhood onset (HP:0011463) | 1.46680742 |
| 85 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 1.43587446 |
| 86 | Deviation of the thumb (HP:0009603) | 1.43278166 |
| 87 | Abnormal hemoglobin (HP:0011902) | 1.42464475 |
| 88 | Tetraplegia (HP:0002445) | 1.41924982 |
| 89 | Abnormality of the epiphysis of the femoral head (HP:0010574) | 1.40557194 |
| 90 | Renal cortical cysts (HP:0000803) | 1.37597892 |
| 91 | Hyponatremia (HP:0002902) | 1.35644488 |
| 92 | Camptodactyly of toe (HP:0001836) | 1.33847602 |
| 93 | Cardiomegaly (HP:0001640) | 1.32980718 |
| 94 | Abnormality of femoral epiphyses (HP:0006499) | 1.32306475 |
| 95 | Abnormality involving the epiphyses of the lower limbs (HP:0006500) | 1.32306475 |
| 96 | Abnormally folded helix (HP:0008544) | 1.30723608 |
| 97 | Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204) | 1.29264260 |
| 98 | Abnormality of the femoral head (HP:0003368) | 1.28610218 |
| 99 | Hypoplasia of the uterus (HP:0000013) | 1.26758863 |
| 100 | Hemivertebrae (HP:0002937) | 1.26575209 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | GRK7 | 7.31121153 |
| 2 | MOS | 6.63071777 |
| 3 | TGFBR2 | 6.51721899 |
| 4 | STK10 | 4.25695494 |
| 5 | GRK5 | 3.92107224 |
| 6 | MAP3K10 | 3.18299659 |
| 7 | INSRR | 2.81150475 |
| 8 | AKT3 | 2.70124905 |
| 9 | PTK2 | 2.38839076 |
| 10 | EIF2AK2 | 2.27222376 |
| 11 | NUAK1 | 2.23584174 |
| 12 | KIT | 2.06852693 |
| 13 | DMPK | 1.65349596 |
| 14 | LRRK2 | 1.47161594 |
| 15 | ADRBK1 | 1.46092333 |
| 16 | HCK | 1.25918965 |
| 17 | FRK | 1.17765835 |
| 18 | PINK1 | 1.09977349 |
| 19 | IRAK4 | 1.05606036 |
| 20 | CLK1 | 1.05486319 |
| 21 | MAP4K2 | 0.97421008 |
| 22 | MUSK | 0.93830471 |
| 23 | FLT3 | 0.93537543 |
| 24 | MAPK13 | 0.90330327 |
| 25 | AURKA | 0.84300257 |
| 26 | SYK | 0.82104735 |
| 27 | PRKCG | 0.79447365 |
| 28 | TNIK | 0.79171526 |
| 29 | STK16 | 0.77570051 |
| 30 | RAF1 | 0.73925850 |
| 31 | NME2 | 0.72620641 |
| 32 | PLK4 | 0.67461522 |
| 33 | TLK1 | 0.66624282 |
| 34 | WNK3 | 0.66581666 |
| 35 | BRAF | 0.65580952 |
| 36 | IRAK2 | 0.64173810 |
| 37 | LCK | 0.63762223 |
| 38 | PRKCD | 0.63367717 |
| 39 | ADRBK2 | 0.62484123 |
| 40 | CDK4 | 0.61510538 |
| 41 | ABL1 | 0.61048835 |
| 42 | PHKG2 | 0.61027663 |
| 43 | PHKG1 | 0.61027663 |
| 44 | MAP3K4 | 0.60137639 |
| 45 | MAPKAPK2 | 0.59681055 |
| 46 | FES | 0.57119489 |
| 47 | RPS6KA5 | 0.56474550 |
| 48 | PDK1 | 0.55768628 |
| 49 | PRKG1 | 0.53506032 |
| 50 | PIM1 | 0.52532820 |
| 51 | JAK2 | 0.52131036 |
| 52 | PAK1 | 0.51642460 |
| 53 | TEC | 0.48391459 |
| 54 | ILK | 0.46933344 |
| 55 | OXSR1 | 0.46200986 |
| 56 | TIE1 | 0.46059135 |
| 57 | BMPR1B | 0.45454237 |
| 58 | PRKACA | 0.45307051 |
| 59 | OBSCN | 0.44651734 |
| 60 | LYN | 0.42597959 |
| 61 | CSF1R | 0.41290930 |
| 62 | TSSK6 | 0.40951041 |
| 63 | IGF1R | 0.40481116 |
| 64 | ZAK | 0.38254569 |
| 65 | BLK | 0.37992707 |
| 66 | GRK1 | 0.37712850 |
| 67 | DYRK3 | 0.34812244 |
| 68 | KDR | 0.33241889 |
| 69 | DYRK2 | 0.31267140 |
| 70 | PRKCB | 0.30933186 |
| 71 | MATK | 0.30858876 |
| 72 | PRKCQ | 0.27518406 |
| 73 | IRAK1 | 0.26413922 |
| 74 | PRKCE | 0.26387860 |
| 75 | SGK1 | 0.23339369 |
| 76 | TXK | 0.23168203 |
| 77 | RPS6KA4 | 0.22197896 |
| 78 | TNK2 | 0.21775479 |
| 79 | VRK1 | 0.21473711 |
| 80 | JAK1 | 0.21016944 |
| 81 | PRKACB | 0.20626766 |
| 82 | ACVR1B | 0.19747828 |
| 83 | SGK223 | 0.19403137 |
| 84 | SGK494 | 0.19403137 |
| 85 | BMPR2 | 0.19119070 |
| 86 | PRKDC | 0.18726915 |
| 87 | MINK1 | 0.18561033 |
| 88 | INSR | 0.17493569 |
| 89 | SGK2 | 0.16954314 |
| 90 | SRC | 0.16479329 |
| 91 | MAPK12 | 0.16221927 |
| 92 | BMX | 0.16207650 |
| 93 | CSNK2A1 | 0.16077490 |
| 94 | MAP2K7 | 0.15924934 |
| 95 | ROCK1 | 0.15455480 |
| 96 | BRD4 | 0.13822053 |
| 97 | FER | 0.13042959 |
| 98 | PRKCA | 0.12895061 |
| 99 | MAP2K6 | 0.11857703 |
| 100 | PRKACG | 0.10015894 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Primary immunodeficiency_Homo sapiens_hsa05340 | 3.98205018 |
| 2 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 3.50322903 |
| 3 | ABC transporters_Homo sapiens_hsa02010 | 3.43637405 |
| 4 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 3.40522462 |
| 5 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 3.08056467 |
| 6 | Histidine metabolism_Homo sapiens_hsa00340 | 2.81258620 |
| 7 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 2.63842214 |
| 8 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 2.52585795 |
| 9 | Basal transcription factors_Homo sapiens_hsa03022 | 2.51729209 |
| 10 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 2.49566238 |
| 11 | Antigen processing and presentation_Homo sapiens_hsa04612 | 2.37042277 |
| 12 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 2.21735578 |
| 13 | Proteasome_Homo sapiens_hsa03050 | 2.11974054 |
| 14 | Ribosome_Homo sapiens_hsa03010 | 2.02018581 |
| 15 | Salivary secretion_Homo sapiens_hsa04970 | 1.92633836 |
| 16 | Asthma_Homo sapiens_hsa05310 | 1.88020403 |
| 17 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 1.81169335 |
| 18 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.75737691 |
| 19 | Allograft rejection_Homo sapiens_hsa05330 | 1.73432979 |
| 20 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.72053292 |
| 21 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.66638756 |
| 22 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.55237112 |
| 23 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.51618201 |
| 24 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 1.48509550 |
| 25 | Mineral absorption_Homo sapiens_hsa04978 | 1.41638153 |
| 26 | Viral myocarditis_Homo sapiens_hsa05416 | 1.35947226 |
| 27 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 1.34529335 |
| 28 | Protein digestion and absorption_Homo sapiens_hsa04974 | 1.27804635 |
| 29 | Retinol metabolism_Homo sapiens_hsa00830 | 1.26539702 |
| 30 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.23974861 |
| 31 | Protein export_Homo sapiens_hsa03060 | 1.22588576 |
| 32 | Phagosome_Homo sapiens_hsa04145 | 1.22168965 |
| 33 | Tyrosine metabolism_Homo sapiens_hsa00350 | 1.18925902 |
| 34 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 1.18053740 |
| 35 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 1.15170492 |
| 36 | Taste transduction_Homo sapiens_hsa04742 | 1.13702027 |
| 37 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.13491371 |
| 38 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 1.12558823 |
| 39 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.10676352 |
| 40 | Gastric acid secretion_Homo sapiens_hsa04971 | 1.06577029 |
| 41 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.04783936 |
| 42 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.03284075 |
| 43 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.97498066 |
| 44 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.96887016 |
| 45 | Olfactory transduction_Homo sapiens_hsa04740 | 0.96245709 |
| 46 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.95733644 |
| 47 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.94845393 |
| 48 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.93836985 |
| 49 | Bile secretion_Homo sapiens_hsa04976 | 0.93622606 |
| 50 | Phototransduction_Homo sapiens_hsa04744 | 0.91949573 |
| 51 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.89431804 |
| 52 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.85743486 |
| 53 | Parkinsons disease_Homo sapiens_hsa05012 | 0.85551042 |
| 54 | Huntingtons disease_Homo sapiens_hsa05016 | 0.82551886 |
| 55 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.79950358 |
| 56 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.77664288 |
| 57 | Insulin secretion_Homo sapiens_hsa04911 | 0.74940777 |
| 58 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.74574092 |
| 59 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.73372526 |
| 60 | Nicotine addiction_Homo sapiens_hsa05033 | 0.73009797 |
| 61 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.71135074 |
| 62 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.67020806 |
| 63 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.66547734 |
| 64 | Renin secretion_Homo sapiens_hsa04924 | 0.65679692 |
| 65 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.64633321 |
| 66 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.62432164 |
| 67 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.60045263 |
| 68 | Malaria_Homo sapiens_hsa05144 | 0.58687681 |
| 69 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.56455924 |
| 70 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.52849488 |
| 71 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.52348804 |
| 72 | Alzheimers disease_Homo sapiens_hsa05010 | 0.52275945 |
| 73 | Alcoholism_Homo sapiens_hsa05034 | 0.52180350 |
| 74 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.51551325 |
| 75 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.49726419 |
| 76 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.47377535 |
| 77 | RNA polymerase_Homo sapiens_hsa03020 | 0.45399177 |
| 78 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.44332698 |
| 79 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.39855491 |
| 80 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.38772714 |
| 81 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.37608946 |
| 82 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.37390459 |
| 83 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.36968258 |
| 84 | Leishmaniasis_Homo sapiens_hsa05140 | 0.36302166 |
| 85 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.35853201 |
| 86 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.35011568 |
| 87 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.34761695 |
| 88 | Peroxisome_Homo sapiens_hsa04146 | 0.34328039 |
| 89 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.32079048 |
| 90 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.31062597 |
| 91 | GABAergic synapse_Homo sapiens_hsa04727 | 0.30247640 |
| 92 | Tuberculosis_Homo sapiens_hsa05152 | 0.26960900 |
| 93 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.26885532 |
| 94 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.26749299 |
| 95 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.25419129 |
| 96 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.24430751 |
| 97 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.24110993 |
| 98 | Morphine addiction_Homo sapiens_hsa05032 | 0.18146401 |
| 99 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.17412065 |
| 100 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.16230139 |

