PCNX3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1positive regulation of histone deacetylation (GO:0031065)4.63070720
2activation of Rac GTPase activity (GO:0032863)4.00278208
3pre-miRNA processing (GO:0031054)3.73427436
4regulation of gamma-delta T cell differentiation (GO:0045586)3.64022016
5positive regulation of Cdc42 GTPase activity (GO:0043089)3.56965297
6antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.54876651
7antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.54876651
8positive thymic T cell selection (GO:0045059)3.50326358
9semaphorin-plexin signaling pathway (GO:0071526)3.49987604
10cytoplasmic mRNA processing body assembly (GO:0033962)3.38527855
11positive regulation of gamma-delta T cell activation (GO:0046645)3.29572310
12negative regulation of cell size (GO:0045792)3.27224389
13regulation of histone H3-K27 methylation (GO:0061085)3.26628807
14antigen processing and presentation of endogenous antigen (GO:0019883)3.25887237
15desmosome organization (GO:0002934)3.22632925
16hemidesmosome assembly (GO:0031581)3.19965339
17retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)3.19912027
18regulation of cholesterol homeostasis (GO:2000188)3.19896039
19regulation of glucose import in response to insulin stimulus (GO:2001273)3.17243574
20regulation of translational fidelity (GO:0006450)3.15333483
21cytoskeletal anchoring at plasma membrane (GO:0007016)3.15232699
22insulin-like growth factor receptor signaling pathway (GO:0048009)3.15122358
23apoptotic cell clearance (GO:0043277)3.14751634
24regulation of gamma-delta T cell activation (GO:0046643)3.14359097
25basement membrane organization (GO:0071711)3.13796221
26protein retention in ER lumen (GO:0006621)3.09977964
27positive regulation of protein deacetylation (GO:0090312)3.07924576
28glucocorticoid receptor signaling pathway (GO:0042921)3.07015859
29peptidyl-lysine dimethylation (GO:0018027)3.04951760
30peptidyl-tyrosine autophosphorylation (GO:0038083)3.04756679
31regulation of NFAT protein import into nucleus (GO:0051532)3.03610174
32negative regulation of erythrocyte differentiation (GO:0045647)3.03569106
33maintenance of protein localization in endoplasmic reticulum (GO:0035437)3.02944275
34embryonic process involved in female pregnancy (GO:0060136)3.00721432
35regulation of fatty acid beta-oxidation (GO:0031998)2.96663198
36negative regulation of viral release from host cell (GO:1902187)2.96483261
37mannose metabolic process (GO:0006013)2.96221056
38positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.95866411
39regulation of early endosome to late endosome transport (GO:2000641)2.94293698
40thymic T cell selection (GO:0045061)2.92236859
41endothelial cell chemotaxis (GO:0035767)2.91884482
42regulation of mammary gland epithelial cell proliferation (GO:0033599)2.87921407
43adherens junction assembly (GO:0034333)2.84824455
44response to laminar fluid shear stress (GO:0034616)2.83894669
45regulation of extracellular matrix disassembly (GO:0010715)2.83388438
46maternal placenta development (GO:0001893)2.83251719
47cortical actin cytoskeleton organization (GO:0030866)2.82737250
48NLS-bearing protein import into nucleus (GO:0006607)2.81960771
49negative regulation of cell killing (GO:0031342)2.81735300
50negative regulation of leukocyte mediated cytotoxicity (GO:0001911)2.81735300
51epithelial cell-cell adhesion (GO:0090136)2.79713512
52activation of signaling protein activity involved in unfolded protein response (GO:0006987)2.79084417
53intracellular estrogen receptor signaling pathway (GO:0030520)2.78493607
54branching involved in mammary gland duct morphogenesis (GO:0060444)2.76997977
55epithelial cell differentiation involved in prostate gland development (GO:0060742)2.76267654
56positive regulation of blood vessel endothelial cell migration (GO:0043536)2.76129885
57regulation of chromatin binding (GO:0035561)2.74785888
58heterochromatin organization (GO:0070828)2.74052648
59negative regulation of fatty acid transport (GO:2000192)2.72852273
60cell-substrate junction assembly (GO:0007044)2.72721368
61embryonic eye morphogenesis (GO:0048048)2.72043443
62proline biosynthetic process (GO:0006561)2.70905380
63positive regulation of nuclease activity (GO:0032075)2.69066111
64cell-cell junction maintenance (GO:0045217)2.67833340
65regulation of cholesterol biosynthetic process (GO:0045540)2.63594124
66regulation of vascular endothelial growth factor signaling pathway (GO:1900746)2.63375186
67regulation of interleukin-12 biosynthetic process (GO:0045075)2.63240289
68positive regulation of transcription from RNA polymerase III promoter (GO:0045945)2.62686663
69spliceosomal tri-snRNP complex assembly (GO:0000244)2.62108888
70growth hormone receptor signaling pathway (GO:0060396)2.60886834
71glucose catabolic process (GO:0006007)2.60627592
72mRNA stabilization (GO:0048255)2.60392351
73RNA stabilization (GO:0043489)2.60392351
74regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)2.59472583
75atrioventricular valve morphogenesis (GO:0003181)2.59369692
76activation of JUN kinase activity (GO:0007257)2.58065429
77Golgi transport vesicle coating (GO:0048200)2.57216779
78COPI coating of Golgi vesicle (GO:0048205)2.57216779
79positive regulation of glycogen biosynthetic process (GO:0045725)2.56450451
80cell-substrate adherens junction assembly (GO:0007045)2.55604912
81focal adhesion assembly (GO:0048041)2.55604912
82positive regulation of gene expression, epigenetic (GO:0045815)2.54722593
83positive T cell selection (GO:0043368)2.54671818
84regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.54304580
85positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:003602.54265014
86protein localization to endosome (GO:0036010)2.54223242
87corticosteroid receptor signaling pathway (GO:0031958)2.53982079
883-UTR-mediated mRNA stabilization (GO:0070935)2.53397081
89regulation of ARF GTPase activity (GO:0032312)2.52535844
90modulation by symbiont of host cellular process (GO:0044068)2.52337921
91positive regulation of receptor recycling (GO:0001921)2.52143984
92negative regulation of histone methylation (GO:0031061)2.50374666
93planar cell polarity pathway involved in neural tube closure (GO:0090179)2.50071722
94positive regulation of fatty acid beta-oxidation (GO:0032000)2.49788192
95pentose-phosphate shunt (GO:0006098)2.49571777
96modulation by virus of host morphology or physiology (GO:0019048)2.49297832
97natural killer cell differentiation (GO:0001779)2.48887987
98cellular response to epidermal growth factor stimulus (GO:0071364)2.48883250
99JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)2.47704462
100regulation of histone deacetylation (GO:0031063)2.47046274
101cellular response to virus (GO:0098586)2.46888662
102T cell selection (GO:0045058)2.46764106
103stress fiber assembly (GO:0043149)2.45801744
104embryonic camera-type eye morphogenesis (GO:0048596)2.44858019
105glucose 6-phosphate metabolic process (GO:0051156)2.44424060
106negative thymic T cell selection (GO:0045060)2.42275699
107receptor catabolic process (GO:0032801)2.41459880
108regulation of nuclease activity (GO:0032069)2.41240570
109regulation of ARF protein signal transduction (GO:0032012)2.41150230
110regulation of integrin activation (GO:0033623)2.40433706
111negative regulation of lipid transport (GO:0032369)2.39916209
112L-alpha-amino acid transmembrane transport (GO:1902475)2.39222280
113positive regulation of keratinocyte differentiation (GO:0045618)2.39073575
114modulation by virus of host process (GO:0019054)2.38310507
115regulation of cholesterol storage (GO:0010885)2.37507231
116response to fluid shear stress (GO:0034405)2.36829803
117NIK/NF-kappaB signaling (GO:0038061)2.36028341
118response to peptidoglycan (GO:0032494)2.34007188
119cellular response to growth hormone stimulus (GO:0071378)2.33706961
120negative T cell selection (GO:0043383)2.32577152
121pinocytosis (GO:0006907)2.31011453
122snRNA metabolic process (GO:0016073)2.30791803
123regulation of hippo signaling (GO:0035330)2.30497527
124apoptotic process involved in morphogenesis (GO:0060561)2.30426472
125antigen processing and presentation via MHC class Ib (GO:0002475)2.29548480
126regulation of type I interferon-mediated signaling pathway (GO:0060338)2.28534811
127response to muramyl dipeptide (GO:0032495)2.28290986
128signal complex assembly (GO:0007172)2.28127555
129endoplasmic reticulum unfolded protein response (GO:0030968)2.28043135
130vascular endothelial growth factor receptor signaling pathway (GO:0048010)2.27426912
131histone H3-K9 demethylation (GO:0033169)2.27124655
132ear development (GO:0043583)2.26818620
133apoptotic process involved in development (GO:1902742)2.24773611
134ER-nucleus signaling pathway (GO:0006984)2.24675980
135positive regulation of p38MAPK cascade (GO:1900745)2.24511475
136positive regulation of triglyceride biosynthetic process (GO:0010867)2.24088361
137negative regulation of phosphatidylinositol 3-kinase signaling (GO:0014067)2.23183362
138barbed-end actin filament capping (GO:0051016)2.23090072
139cortical cytoskeleton organization (GO:0030865)2.21781641
140regulation of nucleobase-containing compound transport (GO:0032239)2.21207158
141germ cell migration (GO:0008354)2.21056635
142regulation of polysaccharide biosynthetic process (GO:0032885)2.20704131
143activation of MAPKKK activity (GO:0000185)2.19635627
144protein heterotrimerization (GO:0070208)2.19628611
145membrane protein ectodomain proteolysis (GO:0006509)2.19592924
146positive regulation of Rap GTPase activity (GO:0032854)2.19300501
147negative regulation of cardiac muscle tissue growth (GO:0055022)2.18979080
148negative regulation of heart growth (GO:0061117)2.18979080
149embryonic retina morphogenesis in camera-type eye (GO:0060059)2.18523521
150vascular endothelial growth factor signaling pathway (GO:0038084)2.18265236
151morphogenesis of an endothelium (GO:0003159)2.18127655
152endothelial tube morphogenesis (GO:0061154)2.18127655
153positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr2.17979801
154negative regulation of granulocyte differentiation (GO:0030853)2.17652768
155blood vessel endothelial cell migration (GO:0043534)2.17442665
156histone H3-K36 demethylation (GO:0070544)2.17063671
157stress granule assembly (GO:0034063)2.16928988
158polarized epithelial cell differentiation (GO:0030859)2.16623103
159positive regulation of SMAD protein import into nucleus (GO:0060391)2.16514670
160regulation of p38MAPK cascade (GO:1900744)2.14973159
161histone H3-K4 methylation (GO:0051568)2.14284066

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse3.91048473
2MYC_22102868_ChIP-Seq_BL_Human3.69200052
3EGR1_19374776_ChIP-ChIP_THP-1_Human3.26587976
4VDR_21846776_ChIP-Seq_THP-1_Human2.76292608
5TCF7_22412390_ChIP-Seq_EML_Mouse2.71943992
6KDM2B_26808549_Chip-Seq_DND41_Human2.66726970
7KDM2B_26808549_Chip-Seq_SUP-B15_Human2.63880158
8KDM2B_26808549_Chip-Seq_SIL-ALL_Human2.47294842
9KDM2B_26808549_Chip-Seq_HPB-ALL_Human2.46714533
10STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.38407197
11ELK3_25401928_ChIP-Seq_HUVEC_Human2.33219738
12TP63_17297297_ChIP-ChIP_HaCaT_Human2.28523778
13STAT6_21828071_ChIP-Seq_BEAS2B_Human2.20317261
14LXR_22292898_ChIP-Seq_THP-1_Human2.10766625
15FOXM1_23109430_ChIP-Seq_U2OS_Human2.10630924
16EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.02645427
17STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.99334017
18MAF_26560356_Chip-Seq_TH1_Human1.90248465
19UTX_26944678_Chip-Seq_JUKART_Human1.88806278
20TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.87021355
21KDM2B_26808549_Chip-Seq_JURKAT_Human1.85733398
22ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.82113623
23E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.80949780
24KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.79775591
25CLOCK_20551151_ChIP-Seq_293T_Human1.75473870
26KDM2B_26808549_Chip-Seq_K562_Human1.71859235
27RACK7_27058665_Chip-Seq_MCF-7_Human1.70297947
28ZFP281_27345836_Chip-Seq_ESCs_Mouse1.70211301
29ZFP281_18757296_ChIP-ChIP_E14_Mouse1.69708144
30P300_27058665_Chip-Seq_ZR-75-30cells_Human1.69268426
31PPARA_22158963_ChIP-Seq_LIVER_Mouse1.64874052
32VDR_24763502_ChIP-Seq_THP-1_Human1.64729196
33DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.63682947
34ZNF263_19887448_ChIP-Seq_K562_Human1.61647488
35THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.58029244
36WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.54401327
37RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.54342447
38SCL_19346495_ChIP-Seq_HPC-7_Human1.53985824
39RARG_19884340_ChIP-ChIP_MEFs_Mouse1.53234042
40FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.53077449
41DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.52762689
42BRD4_27068464_Chip-Seq_AML-cells_Mouse1.49625930
43KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.45547414
44RXR_22158963_ChIP-Seq_LIVER_Mouse1.44989317
45SMC4_20622854_ChIP-Seq_HELA_Human1.44148620
46NCOR1_26117541_ChIP-Seq_K562_Human1.42870592
47SPI1_23127762_ChIP-Seq_K562_Human1.42661269
48TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.41878069
49TET1_21451524_ChIP-Seq_MESCs_Mouse1.38496843
50ESR2_21235772_ChIP-Seq_MCF-7_Human1.38368385
51IRF8_22096565_ChIP-ChIP_GC-B_Human1.38350857
52FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.37460575
53TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.37449405
54NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.37203971
55TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.36314495
56SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.34001985
57CREB1_26743006_Chip-Seq_LNCaP_Human1.32515503
58EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.32152321
59ATF3_27146783_Chip-Seq_COLON_Human1.31858598
60MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.30574671
61ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.30334821
62MYB_26560356_Chip-Seq_TH1_Human1.29931930
63LXR_22158963_ChIP-Seq_LIVER_Mouse1.28204213
64PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.27746525
65NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.27476945
66ERG_21242973_ChIP-ChIP_JURKAT_Human1.26959351
67FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human1.26948358
68GATA1_19941826_ChIP-Seq_K562_Human1.26466362
69RUNX1_27514584_Chip-Seq_MCF-7_Human1.26026675
70E2F7_22180533_ChIP-Seq_HELA_Human1.25317627
71NFIB_24661679_ChIP-Seq_LUNG_Mouse1.25097893
72KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.24892748
73TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.24692079
74RUNX_20019798_ChIP-Seq_JUKART_Human1.24623389
75SREBP2_21459322_ChIP-Seq_LIVER_Mouse1.22844654
76NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.22651175
77EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.22249551
78ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.21668928
79TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.21623188
80MYB_26560356_Chip-Seq_TH2_Human1.21119389
81GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.20874617
82CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.20201715
83CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.19790771
84FOXO3_23340844_ChIP-Seq_DLD1_Human1.19719516
85MAF_26560356_Chip-Seq_TH2_Human1.18843643
86HIF1A_21447827_ChIP-Seq_MCF-7_Human1.18423818
87VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.17246119
88CIITA_25753668_ChIP-Seq_RAJI_Human1.16995235
89TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.15655817
90RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.14223289
91EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.14035237
92RUNX1_22412390_ChIP-Seq_EML_Mouse1.14011002
93P68_20966046_ChIP-Seq_HELA_Human1.12835786
94KLF4_18555785_ChIP-Seq_MESCs_Mouse1.12332742
95UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.12116747
96ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.11361517
97GATA1_19941827_ChIP-Seq_MEL_Mouse1.11319381
98SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.10909771
99TP53_22127205_ChIP-Seq_IMR90_Human1.10358506
100SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.09783211
101GATA1_22383799_ChIP-Seq_G1ME_Mouse1.07532343
102CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.07384056
103TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.06968458
104MYB_21317192_ChIP-Seq_ERMYB_Mouse1.06738846
105STAT3_1855785_ChIP-Seq_MESCs_Mouse1.06473268
106PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.04517336
107ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.04290954
108CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.04088504
109TBX20_22080862_ChIP-Seq_HEART_Mouse1.03963616
110TBX20_22328084_ChIP-Seq_HEART_Mouse1.03963616
111SOX2_27498859_Chip-Seq_STOMACH_Mouse1.03716805
112CTCF_27219007_Chip-Seq_ERYTHROID_Human1.03352000
113BCOR_27268052_Chip-Seq_Bcells_Human1.02067115
114GATA6_25053715_ChIP-Seq_YYC3_Human1.01926649
115SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.01250095
116SRY_22984422_ChIP-ChIP_TESTIS_Rat1.01037028
117UBF1/2_26484160_Chip-Seq_HMECs_Human1.00531723
118RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.00479973
119DNAJC2_21179169_ChIP-ChIP_NT2_Human0.98987607
120MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse0.98902981
121SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.98894829
122ELF1_20517297_ChIP-Seq_JURKAT_Human0.96874314
123TFAP2A_17053090_ChIP-ChIP_MCF-7_Human0.96685870
124ZIC3_20872845_ChIP-ChIP_MESCs_Mouse0.96375205
125CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.96309733
126CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.96281891
127ESR1_21235772_ChIP-Seq_MCF-7_Human0.96260125
128STAT3_20064451_ChIP-Seq_CD4+T_Mouse0.96128432
129SA1_27219007_Chip-Seq_ERYTHROID_Human0.95941606
130NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.95821633

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003705_abnormal_hypodermis_morpholog4.44135174
2MP0003300_gastrointestinal_ulcer3.21859786
3MP0005451_abnormal_body_composition3.13788300
4MP0005076_abnormal_cell_differentiation3.10215687
5MP0010352_gastrointestinal_tract_polyps2.77624206
6MP0009278_abnormal_bone_marrow2.62143152
7MP0008961_abnormal_basal_metabolism2.26416009
8MP0003303_peritoneal_inflammation2.24718112
9MP0003566_abnormal_cell_adhesion2.20870779
10MP0008260_abnormal_autophagy2.17747994
11MP0010234_abnormal_vibrissa_follicle2.04105048
12MP0005409_darkened_coat_color1.96934161
13MP0000569_abnormal_digit_pigmentation1.89296398
14MP0008438_abnormal_cutaneous_collagen1.84936234
15MP0002796_impaired_skin_barrier1.84287856
16MP0001849_ear_inflammation1.79801365
17MP0004185_abnormal_adipocyte_glucose1.63533111
18MP0004808_abnormal_hematopoietic_stem1.61236482
19MP0000685_abnormal_immune_system1.58139633
20MP0000733_abnormal_muscle_development1.57814105
21MP0005023_abnormal_wound_healing1.57608161
22MP0002166_altered_tumor_susceptibility1.52373886
23MP0000678_abnormal_parathyroid_gland1.51202231
24MP0003045_fibrosis1.51105328
25MP0004947_skin_inflammation1.50685622
26MP0002396_abnormal_hematopoietic_system1.49707546
27MP0003252_abnormal_bile_duct1.48110214
28MP0002009_preneoplasia1.48069432
29MP0003091_abnormal_cell_migration1.46762076
30MP0003283_abnormal_digestive_organ1.45077472
31MP0000858_altered_metastatic_potential1.43278009
32MP0009840_abnormal_foam_cell1.41948254
33MP0003191_abnormal_cellular_cholesterol1.39534746
34MP0005310_abnormal_salivary_gland1.35525210
35MP0010307_abnormal_tumor_latency1.34814446
36MP0004381_abnormal_hair_follicle1.34335510
37MP0003279_aneurysm1.34223218
38MP0005501_abnormal_skin_physiology1.32419380
39MP0006054_spinal_hemorrhage1.30832581
40MP0002249_abnormal_larynx_morphology1.30159161
41MP0005397_hematopoietic_system_phenotyp1.30038737
42MP0001545_abnormal_hematopoietic_system1.30038737
43MP0005360_urolithiasis1.27884702
44MP0002877_abnormal_melanocyte_morpholog1.23368110
45MP0004510_myositis1.22906534
46MP0005257_abnormal_intraocular_pressure1.22350701
47MP0004197_abnormal_fetal_growth/weight/1.21475758
48MP0005666_abnormal_adipose_tissue1.21313306
49MP0005375_adipose_tissue_phenotype1.21301017
50MP0001915_intracranial_hemorrhage1.20883369
51MP0003172_abnormal_lysosome_physiology1.18399324
52MP0005387_immune_system_phenotype1.17372076
53MP0001790_abnormal_immune_system1.17372076
54MP0003115_abnormal_respiratory_system1.16696649
55MP0005670_abnormal_white_adipose1.15879065
56MP0010368_abnormal_lymphatic_system1.14426935
57MP0001958_emphysema1.14197187
58MP0001800_abnormal_humoral_immune1.14145922
59MP0000003_abnormal_adipose_tissue1.13964894
60MP0001873_stomach_inflammation1.11318290
61MP0003763_abnormal_thymus_physiology1.09855360
62MP0005275_abnormal_skin_tensile1.09386414
63MP0010630_abnormal_cardiac_muscle1.08613911
64MP0000566_synostosis1.08227100
65MP0001216_abnormal_epidermal_layer1.08194561
66MP0004264_abnormal_extraembryonic_tissu1.06818541
67MP0002086_abnormal_extraembryonic_tissu1.06494118
68MP0000703_abnormal_thymus_morphology1.05773766
69MP0005621_abnormal_cell_physiology1.05008298
70MP0002398_abnormal_bone_marrow1.04111987
71MP0002925_abnormal_cardiovascular_devel1.03772801
72MP0005623_abnormal_meninges_morphology1.02607619
73MP0003436_decreased_susceptibility_to1.01581481
74MP0009053_abnormal_anal_canal1.01298765
75MP0003453_abnormal_keratinocyte_physiol1.00224303
76MP0000537_abnormal_urethra_morphology0.99382866
77MP0004272_abnormal_basement_membrane0.98958536
78MP0002998_abnormal_bone_remodeling0.98838170
79MP0009333_abnormal_splenocyte_physiolog0.98823851
80MP0000467_abnormal_esophagus_morphology0.98609260
81MP0000609_abnormal_liver_physiology0.98009941
82MP0002088_abnormal_embryonic_growth/wei0.96977073
83MP0003984_embryonic_growth_retardation0.96346323
84MP0005464_abnormal_platelet_physiology0.95812411
85MP0009672_abnormal_birth_weight0.95728067
86MP0000490_abnormal_crypts_of0.95561589
87MP0000767_abnormal_smooth_muscle0.95245177
88MP0002098_abnormal_vibrissa_morphology0.94807646
89MP0002928_abnormal_bile_duct0.93797494
90MP0004130_abnormal_muscle_cell0.92887263
91MP0000428_abnormal_craniofacial_morphol0.92481282
92MP0001730_embryonic_growth_arrest0.91988985
93MP0009931_abnormal_skin_appearance0.91083554
94MP0010155_abnormal_intestine_physiology0.90001225
95MP0002060_abnormal_skin_morphology0.89230178
96MP0002089_abnormal_postnatal_growth/wei0.87855106
97MP0002084_abnormal_developmental_patter0.87072665
98MP0002722_abnormal_immune_system0.87068817
99MP0002254_reproductive_system_inflammat0.86490516
100MP0001672_abnormal_embryogenesis/_devel0.85695815
101MP0005380_embryogenesis_phenotype0.85695815
102MP0004858_abnormal_nervous_system0.85565560
103MP0000689_abnormal_spleen_morphology0.85479514
104MP0001533_abnormal_skeleton_physiology0.84854577
105MP0002452_abnormal_antigen_presenting0.84124798
106MP0002006_tumorigenesis0.82978461
107MP0005058_abnormal_lysosome_morphology0.82787116
108MP0000477_abnormal_intestine_morphology0.80707311
109MP0000266_abnormal_heart_morphology0.80620527
110MP0001243_abnormal_dermal_layer0.80559679
111MP0005025_abnormal_response_to0.80423826
112MP0003866_abnormal_defecation0.80188396
113MP0009780_abnormal_chondrocyte_physiolo0.79274438
114MP0010329_abnormal_lipoprotein_level0.79163820
115MP0008770_decreased_survivor_rate0.79076104
116MP0002168_other_aberrant_phenotype0.78807979
117MP0009703_decreased_birth_body0.78414871
118MP0001348_abnormal_lacrimal_gland0.78085972
119MP0004233_abnormal_muscle_weight0.77772356
120MP0000716_abnormal_immune_system0.77601681
121MP0002128_abnormal_blood_circulation0.76656823
122MP0002092_abnormal_eye_morphology0.76647782
123MP0002419_abnormal_innate_immunity0.76400368
124MP0000350_abnormal_cell_proliferation0.76056005
125MP0004087_abnormal_muscle_fiber0.76009184
126MP0002896_abnormal_bone_mineralization0.75728803
127MP0000377_abnormal_hair_follicle0.73071634
128MP0002080_prenatal_lethality0.71041108
129MP0000579_abnormal_nail_morphology0.70723193
130MP0009384_cardiac_valve_regurgitation0.70092154
131MP0005000_abnormal_immune_tolerance0.69832106
132MP0002970_abnormal_white_adipose0.69328383
133MP0004782_abnormal_surfactant_physiolog0.65907694

Predicted human phenotypes

RankGene SetZ-score
1Cerebral aneurysm (HP:0004944)4.23400071
2Broad face (HP:0000283)4.05658016
3Hyperacusis (HP:0010780)3.34330367
4Shallow orbits (HP:0000586)3.11936379
5Abnormality of the fingertips (HP:0001211)3.08662129
6Protrusio acetabuli (HP:0003179)3.05377260
7Obstructive sleep apnea (HP:0002870)2.97850114
8Macroorchidism (HP:0000053)2.87077615
9Short 4th metacarpal (HP:0010044)2.83123241
10Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.83123241
11Aortic aneurysm (HP:0004942)2.81440704
12Mitral valve prolapse (HP:0001634)2.70400109
13Broad metatarsal (HP:0001783)2.63051449
14Aneurysm (HP:0002617)2.62173339
15Ulnar bowing (HP:0003031)2.60708677
16Upper limb amyotrophy (HP:0009129)2.56336091
17Distal upper limb amyotrophy (HP:0007149)2.56336091
18Abnormality of the distal phalanx of the thumb (HP:0009617)2.52658563
19Hand muscle atrophy (HP:0009130)2.49533453
20Ankle contracture (HP:0006466)2.49089629
21Abnormality of the distal phalanges of the toes (HP:0010182)2.46728272
22Hemorrhage of the eye (HP:0011885)2.46249768
23Long palpebral fissure (HP:0000637)2.41675905
24Distal lower limb amyotrophy (HP:0008944)2.40530043
25Dilatation of the ascending aorta (HP:0005111)2.34437737
26Sparse lateral eyebrow (HP:0005338)2.32438890
27Abnormality of the 4th metacarpal (HP:0010012)2.31749065
28Fragile skin (HP:0001030)2.30882764
29Achilles tendon contracture (HP:0001771)2.29063521
30Elfin facies (HP:0004428)2.26079256
31Asymmetry of the thorax (HP:0001555)2.25104524
32Renovascular hypertension (HP:0100817)2.24721505
33Vertebral compression fractures (HP:0002953)2.22547544
34Lymphangioma (HP:0100764)2.22241798
35Disproportionate tall stature (HP:0001519)2.21280403
36Genu recurvatum (HP:0002816)2.15673389
37J-shaped sella turcica (HP:0002680)2.13687768
38Advanced eruption of teeth (HP:0006288)2.12991825
39Heterotopia (HP:0002282)2.12451776
40Bowel diverticulosis (HP:0005222)2.12164517
41Renal duplication (HP:0000075)2.11843720
42Short nail (HP:0001799)2.11593146
43Abnormality of the Achilles tendon (HP:0005109)2.11523524
44Urethral obstruction (HP:0000796)2.10723202
45Bladder diverticulum (HP:0000015)2.10390835
46Narrow palate (HP:0000189)2.08058063
47Aortic dissection (HP:0002647)2.04806220
48Thin bony cortex (HP:0002753)2.03329321
49Abnormal ossification of hand bones (HP:0005921)2.02908381
50Abnormality of the thoracic spine (HP:0100711)2.02700486
51Enlarged penis (HP:0000040)2.02658538
52Hematochezia (HP:0002573)2.02610509
53Biconcave vertebral bodies (HP:0004586)2.00992214
54Eczematoid dermatitis (HP:0000976)2.00155344
55Long eyelashes (HP:0000527)1.99843572
56Turricephaly (HP:0000262)1.99229800
57Pseudobulbar signs (HP:0002200)1.99122846
58Increased density of long bones (HP:0006392)1.98067083
59Nasal polyposis (HP:0100582)1.97099616
60Colitis (HP:0002583)1.97004983
61Insomnia (HP:0100785)1.94339957
62Abnormality of the nasal mucosa (HP:0000433)1.94329634
63Stridor (HP:0010307)1.93712924
64Abnormality of carpal bone ossification (HP:0006257)1.92719833
65Premature skin wrinkling (HP:0100678)1.91990841
66Dislocated radial head (HP:0003083)1.91338130
67Long toe (HP:0010511)1.91171433
68Premature rupture of membranes (HP:0001788)1.87563769
69Ureteral stenosis (HP:0000071)1.86784263
70Striae distensae (HP:0001065)1.86212712
71Bowing of the arm (HP:0006488)1.85711414
72Bowed forearm bones (HP:0003956)1.85711414
73Autoimmune thrombocytopenia (HP:0001973)1.85627196
74Ankyloglossia (HP:0010296)1.85572426
75Distal lower limb muscle weakness (HP:0009053)1.84999811
76Myocardial infarction (HP:0001658)1.82125959
77Peritonitis (HP:0002586)1.81842462
78Deep venous thrombosis (HP:0002625)1.81043867
79Subacute progressive viral hepatitis (HP:0006572)1.81002581
80Deviation of the hallux (HP:0010051)1.80394539
81Abnormality of the radial head (HP:0003995)1.80184091
82Verrucae (HP:0200043)1.80080952
83Papilloma (HP:0012740)1.80080952
84Hallux valgus (HP:0001822)1.80031515
85Neoplasm of the heart (HP:0100544)1.79639620
86Dysostosis multiplex (HP:0000943)1.79150813
87Abnormal vertebral ossification (HP:0100569)1.77874819
88Radial bowing (HP:0002986)1.76757536
89Broad thumb (HP:0011304)1.76746984
90Gastrointestinal inflammation (HP:0004386)1.76643761
91Trigonocephaly (HP:0000243)1.76622579
92Mitral regurgitation (HP:0001653)1.76529367
93Natal tooth (HP:0000695)1.76143072
94Increased connective tissue (HP:0009025)1.73311782
95Cellulitis (HP:0100658)1.73302066
96Selective tooth agenesis (HP:0001592)1.73218148
97Ureteral obstruction (HP:0006000)1.72864163
98Bicuspid aortic valve (HP:0001647)1.72650290
99Overriding aorta (HP:0002623)1.72644815
100Osteolytic defects of the hand bones (HP:0009699)1.71760098
101Osteolytic defects of the phalanges of the hand (HP:0009771)1.71760098
102Pointed chin (HP:0000307)1.71271190
103Abnormality of the lower motor neuron (HP:0002366)1.70851862
104Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)1.70546149
105Vertebral arch anomaly (HP:0008438)1.70543477
106Dysmetric saccades (HP:0000641)1.69688370
107Patellar dislocation (HP:0002999)1.69598869
108Urinary glycosaminoglycan excretion (HP:0003541)1.69549723
109Mucopolysacchariduria (HP:0008155)1.69549723
110Abnormality of the phalanges of the hallux (HP:0010057)1.69432995
111Broad palm (HP:0001169)1.69393293
112High pitched voice (HP:0001620)1.69254551
113Abnormality of oral frenula (HP:0000190)1.69163169
114Persistence of primary teeth (HP:0006335)1.69128741
115Rectal prolapse (HP:0002035)1.68900601
116Septate vagina (HP:0001153)1.67934876
117Bronchomalacia (HP:0002780)1.67907986
118Germ cell neoplasia (HP:0100728)1.67344659
119Difficulty climbing stairs (HP:0003551)1.67084833
120Coxa vara (HP:0002812)1.66987802
121Micronodular cirrhosis (HP:0001413)1.66601421
122Wormian bones (HP:0002645)1.66522234
123Cervical subluxation (HP:0003308)1.66026031
124Flattened epiphyses (HP:0003071)1.64309896
125Abnormality of the peritoneum (HP:0002585)1.63911870
126Joint laxity (HP:0001388)1.63851186
127Blue sclerae (HP:0000592)1.63230791
128Trismus (HP:0000211)1.62789945
129Thoracic kyphosis (HP:0002942)1.62721979
130Spinal cord lesions (HP:0100561)1.62345544
131Syringomyelia (HP:0003396)1.62345544
132Atrophic scars (HP:0001075)1.62325370
133Skin tags (HP:0010609)1.62109632
134Metaphyseal cupping (HP:0003021)1.61205208
135Recurrent viral infections (HP:0004429)1.61102014
136Inflammation of the large intestine (HP:0002037)1.60924822
137Mitral stenosis (HP:0001718)1.59909144
138Mildly elevated creatine phosphokinase (HP:0008180)1.59599655
139Centrally nucleated skeletal muscle fibers (HP:0003687)1.59553693
140Camptodactyly of toe (HP:0001836)1.59390085
141Emphysema (HP:0002097)1.59316504
142Fatigue (HP:0012378)1.59282172
143Lower limb amyotrophy (HP:0007210)1.59280774
144Arnold-Chiari malformation (HP:0002308)1.58682874
145Back pain (HP:0003418)1.58423614
146Interstitial pulmonary disease (HP:0006530)1.58263986
147Cerebral inclusion bodies (HP:0100314)1.58122625
148Axonal loss (HP:0003447)1.57082982
149Deformed sella turcica (HP:0002681)1.56956629
150Abnormality of polysaccharide metabolism (HP:0011012)1.56861306
151Abnormality of glycosaminoglycan metabolism (HP:0004371)1.56861306
152Abnormality of mucopolysaccharide metabolism (HP:0011020)1.56861306
153Flat acetabular roof (HP:0003180)1.56377931
154Easy fatigability (HP:0003388)1.56372614
155Growth hormone excess (HP:0000845)1.56318914
156Absent frontal sinuses (HP:0002688)1.55840475
157Segmental peripheral demyelination/remyelination (HP:0003481)1.55656567
158Ectopia lentis (HP:0001083)1.55320836
159Bone pain (HP:0002653)1.54759967
160Hyperparathyroidism (HP:0000843)1.54728828
161Frequent falls (HP:0002359)1.53140401
162Polycythemia (HP:0001901)1.52732332
163Milia (HP:0001056)1.51853029
164Astrocytoma (HP:0009592)1.51657738
165Abnormality of the astrocytes (HP:0100707)1.51657738

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TRIB34.34162439
2MAP3K104.01355582
3SMG13.58493682
4EEF2K3.53497201
5PKN23.34591836
6CDK123.26447283
7ERN13.25403638
8PRPF4B2.77367503
9IRAK32.74120758
10MAP4K12.58498794
11SIK12.55666664
12EPHA22.46899653
13ICK2.12316302
14RIPK12.11397236
15PTK62.02298616
16MST1R1.93136289
17TTN1.92913269
18CAMK1D1.81025548
19CAMK1G1.79602856
20PDGFRA1.77290529
21FGFR41.71787843
22SIK21.70268287
23MTOR1.43478205
24TNK21.38005788
25LRRK21.35124675
26TAOK11.34314544
27STK101.32429561
28TGFBR21.30400676
29EPHB11.29252634
30MAP3K31.22378497
31TYK21.21768057
32JAK11.19387393
33LATS11.18532020
34GRK61.18521325
35RIPK41.18495626
36BMX1.18441340
37BRD41.15007014
38MAP3K71.14273365
39ALK1.11521745
40PAK41.10453937
41IRAK41.10365517
42TYRO31.09518771
43SCYL21.07386417
44FGFR31.04449946
45IRAK21.03210141
46CDK61.02896220
47NEK21.00878443
48PRKCH0.99947931
49JAK30.98422504
50ZAP700.97949895
51PDGFRB0.97126769
52NME20.96023604
53CSF1R0.94527571
54LMTK20.93597807
55MAP3K110.92012641
56TAOK20.91047135
57PAK20.90637157
58PRKD30.90379601
59PTK20.89940385
60CDK40.89621173
61DMPK0.87434434
62DDR20.86768150
63TESK20.84661773
64HCK0.80376969
65PDPK10.79454355
66TESK10.79280079
67RET0.79170521
68MET0.75759407
69MARK20.75479624
70MAP2K30.75019018
71PRKD20.74122255
72DYRK1B0.72231054
73SIK30.70116881
74HIPK20.69623266
75CSK0.69452830
76CDC42BPA0.68127507
77JAK20.68124766
78CHUK0.67966483
79CDK70.66988377
80RPS6KC10.66560705
81RPS6KL10.66560705
82MAP2K20.66513787
83FGFR20.66000901
84PIM20.65647789
85ITK0.63902091
86MAP3K140.63815800
87FGFR10.63207212
88FLT30.62759413
89RPS6KA40.61507503
90RPS6KB20.60298114
91TAOK30.58691624
92STK30.56921146
93CDK90.55871106
94PRKCI0.55478264
95SGK30.55079517
96TBK10.54679997
97BTK0.52334863
98MAP3K20.52175460
99MAP3K80.51536090
100ARAF0.51102006
101MAP3K60.50020873
102PRKD10.48984330
103KSR20.48801842
104CAMKK10.48246829
105RPS6KA20.47457553
106PRKG20.47204716
107RPS6KA60.45522731
108MAPKAPK30.43123076
109PIM10.42017545
110MARK30.41562859
111LATS20.41248954
112WNK10.41166163
113MELK0.41025688
114RPS6KA10.40256718
115KIT0.39082338
116EGFR0.38641692
117MAPK110.37411021
118LCK0.37038749
119PASK0.36599200
120MAPKAPK20.35370862
121NTRK10.35179070
122STK380.34925378
123PDK10.34395560
124FER0.34269586
125EPHA30.34175634
126ERBB20.34032813
127MAPK10.33851539
128CAMK40.32759809
129STK110.32732742
130SRC0.31604068
131KDR0.31100076
132MAP3K130.30572352
133TGFBR10.30471519
134MAP3K10.29529488
135EPHB20.29196058
136INSR0.29048754
137CLK10.29016576

Predicted pathways (KEGG)

RankGene SetZ-score
1Other glycan degradation_Homo sapiens_hsa005112.46429618
2Lysine degradation_Homo sapiens_hsa003102.18840987
3Chronic myeloid leukemia_Homo sapiens_hsa052201.96513026
4Nitrogen metabolism_Homo sapiens_hsa009101.94915232
5B cell receptor signaling pathway_Homo sapiens_hsa046621.78234495
6Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.72852749
7Fatty acid biosynthesis_Homo sapiens_hsa000611.65279929
8mTOR signaling pathway_Homo sapiens_hsa041501.55720821
9Notch signaling pathway_Homo sapiens_hsa043301.54790422
10Insulin resistance_Homo sapiens_hsa049311.51109369
11Small cell lung cancer_Homo sapiens_hsa052221.40046899
12Acute myeloid leukemia_Homo sapiens_hsa052211.39000773
13Proteoglycans in cancer_Homo sapiens_hsa052051.37815100
14Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.34904719
15Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.32972217
16Non-small cell lung cancer_Homo sapiens_hsa052231.31606853
17Focal adhesion_Homo sapiens_hsa045101.31485710
18Osteoclast differentiation_Homo sapiens_hsa043801.29291920
19AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.24955171
20Neurotrophin signaling pathway_Homo sapiens_hsa047221.24418744
21Type II diabetes mellitus_Homo sapiens_hsa049301.21864973
22Pancreatic cancer_Homo sapiens_hsa052121.20758286
23Adherens junction_Homo sapiens_hsa045201.19820666
24Hepatitis C_Homo sapiens_hsa051601.19533945
25Thyroid hormone signaling pathway_Homo sapiens_hsa049191.19349058
26Toxoplasmosis_Homo sapiens_hsa051451.18336875
27Endometrial cancer_Homo sapiens_hsa052131.17693063
28ErbB signaling pathway_Homo sapiens_hsa040121.17401461
29Primary immunodeficiency_Homo sapiens_hsa053401.14924564
30T cell receptor signaling pathway_Homo sapiens_hsa046601.12414577
31MicroRNAs in cancer_Homo sapiens_hsa052061.12206407
32Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.11150592
33Central carbon metabolism in cancer_Homo sapiens_hsa052301.09755579
34Leukocyte transendothelial migration_Homo sapiens_hsa046701.09297587
35Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.08941215
36VEGF signaling pathway_Homo sapiens_hsa043701.08804069
37Glioma_Homo sapiens_hsa052141.08712630
38Dorso-ventral axis formation_Homo sapiens_hsa043201.08704507
39Longevity regulating pathway - mammal_Homo sapiens_hsa042111.06740751
40Fructose and mannose metabolism_Homo sapiens_hsa000511.06507117
41Prion diseases_Homo sapiens_hsa050201.06009165
42Cyanoamino acid metabolism_Homo sapiens_hsa004601.05402571
43Adipocytokine signaling pathway_Homo sapiens_hsa049201.04517707
44Pentose phosphate pathway_Homo sapiens_hsa000301.04232067
45Viral myocarditis_Homo sapiens_hsa054161.04112776
46ECM-receptor interaction_Homo sapiens_hsa045121.03698119
47Platelet activation_Homo sapiens_hsa046111.02675287
48Amoebiasis_Homo sapiens_hsa051461.01643836
49Choline metabolism in cancer_Homo sapiens_hsa052311.01485297
50Carbohydrate digestion and absorption_Homo sapiens_hsa049731.00429966
51Inositol phosphate metabolism_Homo sapiens_hsa005621.00393509
52Insulin signaling pathway_Homo sapiens_hsa049100.99705568
53Colorectal cancer_Homo sapiens_hsa052100.98853289
54GnRH signaling pathway_Homo sapiens_hsa049120.95084309
55Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.94635094
56Basal cell carcinoma_Homo sapiens_hsa052170.93062925
57Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.92584523
58Estrogen signaling pathway_Homo sapiens_hsa049150.92277161
59HTLV-I infection_Homo sapiens_hsa051660.91472225
60Bladder cancer_Homo sapiens_hsa052190.91152493
61Leishmaniasis_Homo sapiens_hsa051400.90980549
62AMPK signaling pathway_Homo sapiens_hsa041520.89627689
63Bile secretion_Homo sapiens_hsa049760.89420219
64Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.86875525
65Antigen processing and presentation_Homo sapiens_hsa046120.86322784
66Prolactin signaling pathway_Homo sapiens_hsa049170.85384148
67Galactose metabolism_Homo sapiens_hsa000520.84513435
68Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.84406765
69Renal cell carcinoma_Homo sapiens_hsa052110.83387338
70Hepatitis B_Homo sapiens_hsa051610.81815777
71Staphylococcus aureus infection_Homo sapiens_hsa051500.81465019
72Prostate cancer_Homo sapiens_hsa052150.80257687
73ABC transporters_Homo sapiens_hsa020100.79900738
74N-Glycan biosynthesis_Homo sapiens_hsa005100.77602094
75Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.75947614
76Sphingolipid signaling pathway_Homo sapiens_hsa040710.75600396
77Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.75260116
78Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.74551886
79Regulation of actin cytoskeleton_Homo sapiens_hsa048100.74482480
80Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.73880147
81Lysosome_Homo sapiens_hsa041420.73719940
82Glycosaminoglycan degradation_Homo sapiens_hsa005310.73023532
83Apoptosis_Homo sapiens_hsa042100.71702331
84Glucagon signaling pathway_Homo sapiens_hsa049220.71561904
85Chemokine signaling pathway_Homo sapiens_hsa040620.71338886
86NF-kappa B signaling pathway_Homo sapiens_hsa040640.70446379
87Protein digestion and absorption_Homo sapiens_hsa049740.70160753
88Caffeine metabolism_Homo sapiens_hsa002320.70092197
89Hippo signaling pathway_Homo sapiens_hsa043900.69528848
90Phosphatidylinositol signaling system_Homo sapiens_hsa040700.69516265
91Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.68971679
92Rap1 signaling pathway_Homo sapiens_hsa040150.68665430
93TNF signaling pathway_Homo sapiens_hsa046680.68643993
94Aldosterone synthesis and secretion_Homo sapiens_hsa049250.68318199
95Transcriptional misregulation in cancer_Homo sapiens_hsa052020.67949826
96FoxO signaling pathway_Homo sapiens_hsa040680.67862118
97Phospholipase D signaling pathway_Homo sapiens_hsa040720.67589827
98Viral carcinogenesis_Homo sapiens_hsa052030.67419928
99Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.67369917
100Pathways in cancer_Homo sapiens_hsa052000.67230977
101PPAR signaling pathway_Homo sapiens_hsa033200.67175875
102Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.66671322
103Measles_Homo sapiens_hsa051620.66179300
104Jak-STAT signaling pathway_Homo sapiens_hsa046300.65758701
105Arginine biosynthesis_Homo sapiens_hsa002200.65578698
106Endocytosis_Homo sapiens_hsa041440.65487532
107Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.62785298
108Tuberculosis_Homo sapiens_hsa051520.62480948
109Shigellosis_Homo sapiens_hsa051310.61475198
110RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.61241636
111HIF-1 signaling pathway_Homo sapiens_hsa040660.59789852
112Salmonella infection_Homo sapiens_hsa051320.59673116
113Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.59586186
114Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.59477628
115Vibrio cholerae infection_Homo sapiens_hsa051100.58558303
116Influenza A_Homo sapiens_hsa051640.57452262
117Complement and coagulation cascades_Homo sapiens_hsa046100.56422619
118Selenocompound metabolism_Homo sapiens_hsa004500.55708096
119Toll-like receptor signaling pathway_Homo sapiens_hsa046200.55606974
120Renin-angiotensin system_Homo sapiens_hsa046140.53365071
121Thyroid cancer_Homo sapiens_hsa052160.52449088
122Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.50819257
123Herpes simplex infection_Homo sapiens_hsa051680.50248217
124Melanogenesis_Homo sapiens_hsa049160.50216591
125Long-term potentiation_Homo sapiens_hsa047200.48403466

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