PCP2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1cellular potassium ion homeostasis (GO:0030007)8.03222958
2response to pheromone (GO:0019236)7.95554127
3G-protein coupled glutamate receptor signaling pathway (GO:0007216)7.91707397
4fructose metabolic process (GO:0006000)7.20119687
5positive regulation of synapse maturation (GO:0090129)7.10819923
6cerebellar Purkinje cell layer development (GO:0021680)7.05842207
7cerebellar granule cell differentiation (GO:0021707)6.96449857
8protein heterotetramerization (GO:0051290)6.82490821
9metanephric tubule development (GO:0072170)6.69480910
10metanephric nephron tubule development (GO:0072234)6.69480910
11positive regulation of synaptic transmission, GABAergic (GO:0032230)6.34622333
12gamma-aminobutyric acid signaling pathway (GO:0007214)6.32436118
13metanephric nephron epithelium development (GO:0072243)6.21441653
14collecting duct development (GO:0072044)6.12220470
15positive regulation of phosphoprotein phosphatase activity (GO:0032516)5.94078448
16neurofilament cytoskeleton organization (GO:0060052)5.92619660
17multicellular organismal movement (GO:0050879)5.91193320
18musculoskeletal movement (GO:0050881)5.91193320
19detection of light stimulus involved in visual perception (GO:0050908)5.82862339
20detection of light stimulus involved in sensory perception (GO:0050962)5.82862339
21potassium ion homeostasis (GO:0055075)5.80788282
22synaptic vesicle exocytosis (GO:0016079)5.75989456
23cerebellar Purkinje cell differentiation (GO:0021702)5.71429257
24sodium ion export (GO:0071436)5.70626039
25metanephric epithelium development (GO:0072207)5.69867403
26positive regulation of muscle hypertrophy (GO:0014742)5.63430250
27positive regulation of cardiac muscle hypertrophy (GO:0010613)5.63430250
28negative regulation of cytosolic calcium ion concentration (GO:0051481)5.61967244
29regulation of synapse maturation (GO:0090128)5.60483837
30aggressive behavior (GO:0002118)5.47906792
31inositol phosphate-mediated signaling (GO:0048016)5.37605513
32retinal rod cell development (GO:0046548)5.19634601
33cell differentiation in hindbrain (GO:0021533)5.12421232
34neurotransmitter-gated ion channel clustering (GO:0072578)5.11929059
35glutamate receptor signaling pathway (GO:0007215)5.09632176
36positive regulation of calcium ion-dependent exocytosis (GO:0045956)5.09041839
37retina layer formation (GO:0010842)5.08809336
38relaxation of smooth muscle (GO:0044557)5.05740090
39positive regulation of dendritic spine morphogenesis (GO:0061003)4.92860369
40positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.92043513
41negative regulation of norepinephrine secretion (GO:0010700)4.86669166
42regulation of short-term neuronal synaptic plasticity (GO:0048172)4.86590985
43locomotory exploration behavior (GO:0035641)4.74177890
44behavioral response to nicotine (GO:0035095)4.70958975
45synaptic vesicle endocytosis (GO:0048488)4.67932669
46negative regulation of heart rate (GO:0010459)4.66072331
47synaptic vesicle maturation (GO:0016188)4.64186771
48positive regulation of glomerulus development (GO:0090193)4.59693701
49peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan (GO:0019800)4.55985469
50cell communication by electrical coupling involved in cardiac conduction (GO:0086064)4.52926482
51regulation of synaptic vesicle exocytosis (GO:2000300)4.46179675
52layer formation in cerebral cortex (GO:0021819)4.44246439
53vocalization behavior (GO:0071625)4.38456727
54regulation of voltage-gated calcium channel activity (GO:1901385)4.28997612
55protein localization to synapse (GO:0035418)4.28760370
56neurotransmitter secretion (GO:0007269)4.22152591
57prepulse inhibition (GO:0060134)4.07771057
58positive regulation of amino acid transport (GO:0051957)4.02161322
59regulation of potassium ion transmembrane transporter activity (GO:1901016)4.00936665
60endoplasmic reticulum calcium ion homeostasis (GO:0032469)3.97426323
61urinary tract smooth muscle contraction (GO:0014848)3.92827367
62chemosensory behavior (GO:0007635)3.92448601
63neuron-neuron synaptic transmission (GO:0007270)3.89659919
64positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.89143582
65innervation (GO:0060384)3.88943897
66ionotropic glutamate receptor signaling pathway (GO:0035235)3.88369075
67nephron tubule development (GO:0072080)3.87347107
68glutamate secretion (GO:0014047)3.86036936
69relaxation of cardiac muscle (GO:0055119)3.85672344
70regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.85099043
71positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)3.85056049
72cell communication by electrical coupling (GO:0010644)3.84967540
73synaptic transmission, glutamatergic (GO:0035249)3.84537565
74regulation of synaptic vesicle transport (GO:1902803)3.83031765
75long-term memory (GO:0007616)3.81394404
76neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976)3.78872392
77regulation of synapse structural plasticity (GO:0051823)3.77158385
78negative regulation of fatty acid transport (GO:2000192)3.76490668
79relaxation of muscle (GO:0090075)3.76064533
80cellular sodium ion homeostasis (GO:0006883)3.74789845
81behavioral response to ethanol (GO:0048149)3.73960635
82response to water (GO:0009415)3.70926209
83auditory receptor cell stereocilium organization (GO:0060088)3.68948823
84dopamine biosynthetic process (GO:0042416)3.66802642
85potassium ion import (GO:0010107)3.66668463
86neuronal action potential propagation (GO:0019227)3.65717568
87regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.64651279
88regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)3.62238813
89membrane depolarization during action potential (GO:0086010)3.61039156
90regulation of synaptic transmission, glutamatergic (GO:0051966)3.58095704
91regulation of potassium ion transmembrane transport (GO:1901379)3.57864091
92neurotransmitter transport (GO:0006836)3.56709637
93parturition (GO:0007567)3.55460009
94mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.54486578
95negative regulation of synaptic transmission, GABAergic (GO:0032229)3.52413569
96positive regulation of potassium ion transmembrane transport (GO:1901381)3.51368017
97cGMP metabolic process (GO:0046068)3.50553758
98G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:00071993.50058943
99membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.49554692
100activation of transmembrane receptor protein tyrosine kinase activity (GO:0007171)3.49539229
101membrane repolarization (GO:0086009)3.47141855
102adult walking behavior (GO:0007628)3.44789183
103regulation of neurotransmitter secretion (GO:0046928)3.44675522
104synaptic vesicle docking involved in exocytosis (GO:0016081)3.44617481
105regulation of vesicle fusion (GO:0031338)3.43780861
106regulation of neurotransmitter transport (GO:0051588)3.42139585
107gamma-aminobutyric acid transport (GO:0015812)3.40697246
108renal tubule development (GO:0061326)3.40506407
109righting reflex (GO:0060013)3.40470125
110detection of temperature stimulus involved in sensory perception of pain (GO:0050965)3.40435254
111detection of temperature stimulus involved in sensory perception (GO:0050961)3.40435254
112striatum development (GO:0021756)3.40229483
113negative regulation of catecholamine secretion (GO:0033604)3.36061361
114membrane hyperpolarization (GO:0060081)3.33068718
115establishment of synaptic vesicle localization (GO:0097480)3.32789657
116synaptic vesicle transport (GO:0048489)3.32789657
117retinal cone cell development (GO:0046549)3.32015197
118serotonin metabolic process (GO:0042428)3.29117497
119positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.28888216
120synapse assembly (GO:0007416)3.28246271
121potassium ion export (GO:0071435)3.26619952
122response to histamine (GO:0034776)3.26477620
123mating behavior (GO:0007617)3.25764240
124regulation of dopamine secretion (GO:0014059)3.25009075
125positive regulation of CREB transcription factor activity (GO:0032793)3.24476526
126endocrine hormone secretion (GO:0060986)3.23063363
127acidic amino acid transport (GO:0015800)3.22716767
128regulation of amine transport (GO:0051952)3.21660332
129behavioral response to cocaine (GO:0048148)3.19909857
130transmission of nerve impulse (GO:0019226)3.19780803
131positive regulation of membrane potential (GO:0045838)3.19695270
132response to ammonium ion (GO:0060359)3.19055906
133nitric oxide biosynthetic process (GO:0006809)3.18108671
134regulation of neurotransmitter uptake (GO:0051580)3.17544779
135positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.17187578
136nephron epithelium development (GO:0072009)3.15545553
137auditory behavior (GO:0031223)3.14171669
138axon cargo transport (GO:0008088)3.12458453
139negative regulation of homotypic cell-cell adhesion (GO:0034111)3.11648572
140positive regulation of dendritic spine development (GO:0060999)3.10650093
141cellular response to ammonium ion (GO:0071242)3.09932576
142response to auditory stimulus (GO:0010996)3.09550876
143negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.09538455
144C4-dicarboxylate transport (GO:0015740)3.08179129
145negative regulation of heart contraction (GO:0045822)3.07331545
146regulation of systemic arterial blood pressure by renin-angiotensin (GO:0003081)3.06333928
147photoreceptor cell development (GO:0042461)3.05923310
148calcium ion import (GO:0070509)3.05069313
149filopodium assembly (GO:0046847)3.04774505
150regulation of neurotransmitter levels (GO:0001505)3.03289336
151sodium ion homeostasis (GO:0055078)3.02294176
152long term synaptic depression (GO:0060292)3.00382683
153primary amino compound metabolic process (GO:1901160)3.00267836
154regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.99087243
155regulation of centriole replication (GO:0046599)2.98853266
156L-glutamate transport (GO:0015813)2.98815044
157regulation of excitatory postsynaptic membrane potential (GO:0060079)2.98279556
158long-term synaptic potentiation (GO:0060291)2.97339042
159one-carbon metabolic process (GO:0006730)2.96738180
160eye photoreceptor cell development (GO:0042462)2.95681422
161sensory perception of taste (GO:0050909)2.94957753
162neuron cell-cell adhesion (GO:0007158)2.94209152
163regulation of axon regeneration (GO:0048679)2.92802090
164regulation of neuron projection regeneration (GO:0070570)2.92802090
165regulation of glutamate receptor signaling pathway (GO:1900449)2.92581858
166regulation of postsynaptic membrane potential (GO:0060078)2.91482721
167detection of temperature stimulus (GO:0016048)2.89130883
168synaptic transmission (GO:0007268)2.86468284
169regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.86099178
170short-term memory (GO:0007614)10.9722809

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human5.28938827
2EZH2_22144423_ChIP-Seq_EOC_Human4.24192753
3GBX2_23144817_ChIP-Seq_PC3_Human3.63964241
4SUZ12_18555785_ChIP-Seq_MESCs_Mouse3.13453200
5GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.99546150
6SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.91668987
7JARID2_20064375_ChIP-Seq_MESCs_Mouse2.79403451
8REST_21632747_ChIP-Seq_MESCs_Mouse2.76669921
9ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.72014069
10RNF2_18974828_ChIP-Seq_MESCs_Mouse2.71635220
11EZH2_18974828_ChIP-Seq_MESCs_Mouse2.71635220
12JARID2_20075857_ChIP-Seq_MESCs_Mouse2.71045710
13EZH2_27294783_Chip-Seq_ESCs_Mouse2.70878895
14IKZF1_21737484_ChIP-ChIP_HCT116_Human2.63362755
15DROSHA_22980978_ChIP-Seq_HELA_Human2.62817603
16SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.58908654
17SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.55879267
18MTF2_20144788_ChIP-Seq_MESCs_Mouse2.53486887
19RBPJ_22232070_ChIP-Seq_NCS_Mouse2.49934036
20SRY_22984422_ChIP-ChIP_TESTIS_Rat2.42756021
21EED_16625203_ChIP-ChIP_MESCs_Mouse2.40073996
22SUZ12_27294783_Chip-Seq_ESCs_Mouse2.35865118
23FUS_26573619_Chip-Seq_HEK293_Human2.32195003
24SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.24536638
25RNF2_27304074_Chip-Seq_ESCs_Mouse2.23587773
26GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.22653503
27TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.19240417
28EZH2_27304074_Chip-Seq_ESCs_Mouse2.17992119
29REST_18959480_ChIP-ChIP_MESCs_Mouse2.16834433
30SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.11871771
31FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.01054008
32PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.99020306
33SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.93322131
34RARB_27405468_Chip-Seq_BRAIN_Mouse1.88674519
35CDX2_19796622_ChIP-Seq_MESCs_Mouse1.85873915
36EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.79556444
37VDR_22108803_ChIP-Seq_LS180_Human1.76323914
38AR_21572438_ChIP-Seq_LNCaP_Human1.74106863
39CTBP1_25329375_ChIP-Seq_LNCAP_Human1.71659091
40SMAD4_21799915_ChIP-Seq_A2780_Human1.65116275
41CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.61207542
42CTBP2_25329375_ChIP-Seq_LNCAP_Human1.57616852
43ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.56284418
44AR_25329375_ChIP-Seq_VCAP_Human1.51240401
45PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.50465611
46BMI1_23680149_ChIP-Seq_NPCS_Mouse1.49553461
47HTT_18923047_ChIP-ChIP_STHdh_Human1.48022476
48P53_22127205_ChIP-Seq_FIBROBLAST_Human1.47449375
49PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.47108691
50TAF15_26573619_Chip-Seq_HEK293_Human1.42528620
51ZNF274_21170338_ChIP-Seq_K562_Hela1.39460121
52UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.38791532
53ELK4_26923725_Chip-Seq_MESODERM_Mouse1.37365218
54PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.36749702
55PIAS1_25552417_ChIP-Seq_VCAP_Human1.36195801
56ZFP57_27257070_Chip-Seq_ESCs_Mouse1.35581394
57RING1B_27294783_Chip-Seq_ESCs_Mouse1.29944870
58CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.29779861
59RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.29779523
60RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.29101097
61STAT3_23295773_ChIP-Seq_U87_Human1.28963732
62MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.25652864
63P300_19829295_ChIP-Seq_ESCs_Human1.25288560
64RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.24713094
65SMAD3_21741376_ChIP-Seq_EPCs_Human1.24207931
66AR_19668381_ChIP-Seq_PC3_Human1.24094205
67CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.22308690
68SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.21501900
69NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.20928592
70SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.20883336
71ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.20281369
72CBX2_27304074_Chip-Seq_ESCs_Mouse1.20072069
73SMAD3_21741376_ChIP-Seq_HESCs_Human1.18825365
74TCF4_23295773_ChIP-Seq_U87_Human1.18787699
75THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.16480381
76OCT1_27270436_Chip-Seq_PROSTATE_Human1.14178154
77DNAJC2_21179169_ChIP-ChIP_NT2_Human1.11332218
78TOP2B_26459242_ChIP-Seq_MCF-7_Human1.10238306
79SALL4_22934838_ChIP-ChIP_CD34+_Human1.10203568
80TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.10102211
81KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.09449778
82TP53_18474530_ChIP-ChIP_U2OS_Human1.09262361
83SMAD4_21741376_ChIP-Seq_HESCs_Human1.09244489
84SMAD4_21741376_ChIP-Seq_EPCs_Human1.08779598
85POU3F2_20337985_ChIP-ChIP_501MEL_Human1.08694325
86FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.08321705
87SREBP1_19666523_ChIP-Seq_LIVER_Mouse1.06518168
88LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.06430021
89KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse1.04399312
90SMAD_19615063_ChIP-ChIP_OVARY_Human1.03547236
91TAF2_19829295_ChIP-Seq_ESCs_Human1.02909722
92WT1_25993318_ChIP-Seq_PODOCYTE_Human1.02758733
93SOX2_21211035_ChIP-Seq_LN229_Gbm1.02630512
94ERG_21242973_ChIP-ChIP_JURKAT_Human1.01276492
95NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.00795829
96BCAT_22108803_ChIP-Seq_LS180_Human0.99718248
97EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.99689710
98TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.99075553
99POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.99075553
100TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.98495355
101RNF2_27304074_Chip-Seq_NSC_Mouse0.97879794
102SMAD3_21741376_ChIP-Seq_ESCs_Human0.97485788
103KDM2B_26808549_Chip-Seq_K562_Human0.96810938
104NR3C1_23031785_ChIP-Seq_PC12_Mouse0.96129986
105TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.95595859
106GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.95060615
107TAL1_26923725_Chip-Seq_HPCs_Mouse0.94911820
108AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.94809099
109YAP1_20516196_ChIP-Seq_MESCs_Mouse0.94335390
110RING1B_27294783_Chip-Seq_NPCs_Mouse0.94254160
111VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.93228065
112ER_23166858_ChIP-Seq_MCF-7_Human0.93083081
113EWS_26573619_Chip-Seq_HEK293_Human0.91771707
114NR3C1_21868756_ChIP-Seq_MCF10A_Human0.91701575
115TBL1_22424771_ChIP-Seq_293T_Human0.91510949
116FOXO1_23066095_ChIP-Seq_LIVER_Mouse0.91508571
117ZNF217_24962896_ChIP-Seq_MCF-7_Human0.91222230
118TCF4_22108803_ChIP-Seq_LS180_Human0.90802074
119IGF1R_20145208_ChIP-Seq_DFB_Human0.90650372
120SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.89314014
121FLI1_21867929_ChIP-Seq_TH2_Mouse0.89293119
122MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.88220733
123KLF5_20875108_ChIP-Seq_MESCs_Mouse0.86339209
124OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.86259325
125NEUROD2_26341353_ChIP-Seq_CORTEX_Mouse0.85607272
126OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.85309531
127TRIM28_17542650_ChIP-ChIP_NTERA2_Human0.82751104
128ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.82131867
129CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.82114452
130RUNX2_22187159_ChIP-Seq_PCA_Human0.81428547
131CTCF_27219007_Chip-Seq_Bcells_Human0.81415941
132TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.80027230

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001984_abnormal_olfaction5.18709711
2MP0009046_muscle_twitch4.51775004
3MP0005551_abnormal_eye_electrophysiolog4.48143339
4MP0003635_abnormal_synaptic_transmissio3.21653755
5MP0004859_abnormal_synaptic_plasticity3.16358179
6MP0006072_abnormal_retinal_apoptosis3.05443017
7MP0008569_lethality_at_weaning3.04801929
8MP0002272_abnormal_nervous_system2.99233057
9MP0002090_abnormal_vision2.98211789
10MP0001188_hyperpigmentation2.90432953
11MP0003880_abnormal_central_pattern2.76633997
12MP0008875_abnormal_xenobiotic_pharmacok2.76416557
13MP0002067_abnormal_sensory_capabilities2.54456853
14MP0002064_seizures2.50161976
15MP0005410_abnormal_fertilization2.49021067
16MP0006292_abnormal_olfactory_placode2.47217353
17MP0005423_abnormal_somatic_nervous2.47172146
18MP0002734_abnormal_mechanical_nocicepti2.43065317
19MP0009745_abnormal_behavioral_response2.39726095
20MP0002184_abnormal_innervation2.36759683
21MP0010386_abnormal_urinary_bladder2.32719518
22MP0008874_decreased_physiological_sensi2.28297942
23MP0001502_abnormal_circadian_rhythm2.25484222
24MP0001486_abnormal_startle_reflex2.25031835
25MP0004742_abnormal_vestibular_system2.23069270
26MP0002063_abnormal_learning/memory/cond2.21237993
27MP0003787_abnormal_imprinting2.10939380
28MP0005253_abnormal_eye_physiology2.08520156
29MP0004142_abnormal_muscle_tone2.06541771
30MP0001968_abnormal_touch/_nociception2.05396370
31MP0004145_abnormal_muscle_electrophysio2.01253278
32MP0001501_abnormal_sleep_pattern1.95344873
33MP0002572_abnormal_emotion/affect_behav1.93740750
34MP0004215_abnormal_myocardial_fiber1.90649345
35MP0002909_abnormal_adrenal_gland1.85697823
36MP0003879_abnormal_hair_cell1.85433731
37MP0001440_abnormal_grooming_behavior1.79854683
38MP0004484_altered_response_of1.76596481
39MP0000013_abnormal_adipose_tissue1.70249642
40MP0008004_abnormal_stomach_pH1.66973102
41MP0002638_abnormal_pupillary_reflex1.66570534
42MP0004036_abnormal_muscle_relaxation1.63773803
43MP0006276_abnormal_autonomic_nervous1.61525332
44MP0002229_neurodegeneration1.59855157
45MP0002822_catalepsy1.59232850
46MP0004233_abnormal_muscle_weight1.58600132
47MP0002736_abnormal_nociception_after1.56724919
48MP0004270_analgesia1.48697518
49MP0005195_abnormal_posterior_eye1.47339611
50MP0004924_abnormal_behavior1.43865509
51MP0005386_behavior/neurological_phenoty1.43865509
52MP0002557_abnormal_social/conspecific_i1.43151414
53MP0004084_abnormal_cardiac_muscle1.40426539
54MP0002882_abnormal_neuron_morphology1.39853396
55MP0000358_abnormal_cell_content/1.35975610
56MP0003950_abnormal_plasma_membrane1.34666927
57MP0000955_abnormal_spinal_cord1.29170173
58MP0004885_abnormal_endolymph1.29094415
59MP0002735_abnormal_chemical_nociception1.23144666
60MP0001970_abnormal_pain_threshold1.22925127
61MP0000566_synostosis1.22439674
62MP0002066_abnormal_motor_capabilities/c1.21000505
63MP0005248_abnormal_Harderian_gland1.18505216
64MP0002752_abnormal_somatic_nervous1.18275442
65MP0008877_abnormal_DNA_methylation1.17220599
66MP0005499_abnormal_olfactory_system1.16508949
67MP0005394_taste/olfaction_phenotype1.16508949
68MP0000003_abnormal_adipose_tissue1.11098846
69MP0001346_abnormal_lacrimal_gland1.09253940
70MP0004811_abnormal_neuron_physiology1.07993585
71MP0005409_darkened_coat_color1.06405219
72MP0003633_abnormal_nervous_system1.06235606
73MP0009697_abnormal_copulation1.01614681
74MP0003632_abnormal_nervous_system0.95696708
75MP0008872_abnormal_physiological_respon0.95645223
76MP0004043_abnormal_pH_regulation0.94591625
77MP0003631_nervous_system_phenotype0.94248665
78MP0001529_abnormal_vocalization0.92970817
79MP0001485_abnormal_pinna_reflex0.92273729
80MP0004147_increased_porphyrin_level0.89485228
81MP0000569_abnormal_digit_pigmentation0.89484640
82MP0005646_abnormal_pituitary_gland0.86629576
83MP0000343_altered_response_to0.86206890
84MP0003329_amyloid_beta_deposits0.84971393
85MP0002089_abnormal_postnatal_growth/wei0.83733214
86MP0000751_myopathy0.82938674
87MP0002152_abnormal_brain_morphology0.81665316
88MP0001765_abnormal_ion_homeostasis0.80523379
89MP0003868_abnormal_feces_composition0.78938748
90MP0002277_abnormal_respiratory_mucosa0.78468520
91MP0003122_maternal_imprinting0.77243573
92MP0000778_abnormal_nervous_system0.77194233
93MP0001324_abnormal_eye_pigmentation0.77148221
94MP0003137_abnormal_impulse_conducting0.76430460
95MP0002733_abnormal_thermal_nociception0.75808708
96MP0005595_abnormal_vascular_smooth0.75678275
97MP0001963_abnormal_hearing_physiology0.75618665
98MP0006035_abnormal_mitochondrial_morpho0.75611581
99MP0000631_abnormal_neuroendocrine_gland0.75278722
100MP0000230_abnormal_systemic_arterial0.75144241
101MP0005623_abnormal_meninges_morphology0.73704003
102MP0008789_abnormal_olfactory_epithelium0.73603376
103MP0003011_delayed_dark_adaptation0.72779086
104MP0003698_abnormal_male_reproductive0.71012566
105MP0005171_absent_coat_pigmentation0.69963497
106MP0005391_vision/eye_phenotype0.69381376
107MP0003634_abnormal_glial_cell0.67127979
108MP0004085_abnormal_heartbeat0.66175103
109MP0002234_abnormal_pharynx_morphology0.65629348
110MP0003866_abnormal_defecation0.65324506
111MP0009379_abnormal_foot_pigmentation0.65133585
112MP0000534_abnormal_ureter_morphology0.63074033
113MP0002069_abnormal_eating/drinking_beha0.62428048
114MP0010329_abnormal_lipoprotein_level0.61958251
115MP0005187_abnormal_penis_morphology0.59562106
116MP0008775_abnormal_heart_ventricle0.59029167
117MP0000538_abnormal_urinary_bladder0.58429344
118MP0002332_abnormal_exercise_endurance0.58203198
119MP0000015_abnormal_ear_pigmentation0.57794529
120MP0005535_abnormal_body_temperature0.56295187
121MP0005464_abnormal_platelet_physiology0.56092307
122MP0000920_abnormal_myelination0.55827065
123MP0005174_abnormal_tail_pigmentation0.53938076
124MP0005620_abnormal_muscle_contractility0.53815048
125MP0000749_muscle_degeneration0.44989855
126MP0001986_abnormal_taste_sensitivity0.44989332
127MP0002083_premature_death0.44632221
128MP0002972_abnormal_cardiac_muscle0.44044577
129MP0001756_abnormal_urination0.43020384
130MP0002161_abnormal_fertility/fecundity0.41198594
131MP0003956_abnormal_body_size0.40124527
132MP0003638_abnormal_response/metabolism_0.39644493
133MP0001299_abnormal_eye_distance/0.38978775

Predicted human phenotypes

RankGene SetZ-score
1Progressive cerebellar ataxia (HP:0002073)7.75556062
2Action tremor (HP:0002345)5.99708892
3Absence seizures (HP:0002121)5.91543470
4Febrile seizures (HP:0002373)5.81255236
5Abnormality of macular pigmentation (HP:0008002)5.71299586
6Epileptic encephalopathy (HP:0200134)5.46186905
7Myokymia (HP:0002411)5.35977372
8Central scotoma (HP:0000603)5.23547903
9Dysdiadochokinesis (HP:0002075)5.08033898
10Focal motor seizures (HP:0011153)4.85129405
11Dialeptic seizures (HP:0011146)4.68423715
12Gaze-evoked nystagmus (HP:0000640)4.55134750
13Atonic seizures (HP:0010819)4.47978134
14Decreased central vision (HP:0007663)4.44288071
15Visual hallucinations (HP:0002367)4.08759827
16Scanning speech (HP:0002168)4.00856619
17Severe visual impairment (HP:0001141)3.90708623
18Cholecystitis (HP:0001082)3.85178815
19Abnormal gallbladder physiology (HP:0012438)3.85178815
20Focal seizures (HP:0007359)3.83050065
21Dysmetric saccades (HP:0000641)3.77208412
22Degeneration of the lateral corticospinal tracts (HP:0002314)3.69528948
23Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)3.69528948
24Dysmetria (HP:0001310)3.68529665
25Increased corneal curvature (HP:0100692)3.67985715
26Keratoconus (HP:0000563)3.67985715
27Generalized tonic-clonic seizures (HP:0002069)3.64179493
28Acute necrotizing encephalopathy (HP:0006965)3.62466967
29Scotoma (HP:0000575)3.41258137
30Horizontal nystagmus (HP:0000666)3.41241684
31Depression (HP:0000716)3.37761880
32Hemiparesis (HP:0001269)3.33419914
33Hemiplegia (HP:0002301)3.28899576
34Septo-optic dysplasia (HP:0100842)3.28653356
35Hyperlipoproteinemia (HP:0010980)3.26474639
36Abnormal mitochondria in muscle tissue (HP:0008316)3.26125715
37Truncal ataxia (HP:0002078)3.11517757
38Abnormality of ocular smooth pursuit (HP:0000617)3.06585899
39Progressive macrocephaly (HP:0004481)3.04694587
40Abnormal rod and cone electroretinograms (HP:0008323)3.03034298
41Impaired smooth pursuit (HP:0007772)2.98463540
42Acute encephalopathy (HP:0006846)2.87216832
43Anxiety (HP:0000739)2.86497446
44Diplopia (HP:0000651)2.86324363
45Abnormality of binocular vision (HP:0011514)2.86324363
46Impaired vibratory sensation (HP:0002495)2.85649747
47Abnormality of the corticospinal tract (HP:0002492)2.85643808
48EEG with generalized epileptiform discharges (HP:0011198)2.80558885
49Ventricular fibrillation (HP:0001663)2.77112928
50Dyschromatopsia (HP:0007641)2.73445585
51Intention tremor (HP:0002080)2.73182958
52Genetic anticipation (HP:0003743)2.72636344
53Epileptiform EEG discharges (HP:0011182)2.72252182
54Mitochondrial inheritance (HP:0001427)2.69442690
55Limb ataxia (HP:0002070)2.50437608
56Broad-based gait (HP:0002136)2.50084170
57Status epilepticus (HP:0002133)2.46160589
58Bony spicule pigmentary retinopathy (HP:0007737)2.38302955
59Autoamputation (HP:0001218)2.37707577
60Mutism (HP:0002300)2.36438543
61Incomplete penetrance (HP:0003829)2.34680522
62Abnormal pupillary function (HP:0007686)2.30490482
63Renal Fanconi syndrome (HP:0001994)2.27666287
64Abnormal eating behavior (HP:0100738)2.23567687
65Prolonged QT interval (HP:0001657)2.22055669
66Insidious onset (HP:0003587)2.21783852
67Termporal pattern (HP:0011008)2.21783852
68Increased hepatocellular lipid droplets (HP:0006565)2.20418092
69Postural tremor (HP:0002174)2.18810922
70Optic nerve hypoplasia (HP:0000609)2.17392722
71Tetraplegia (HP:0002445)2.15266576
72Cerebellar atrophy (HP:0001272)2.15143978
73Abnormality of alanine metabolism (HP:0010916)2.11077793
74Hyperalaninemia (HP:0003348)2.11077793
75Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.11077793
76Abnormality of saccadic eye movements (HP:0000570)2.08898779
77Cerebral edema (HP:0002181)2.07258507
78Hypoplasia of the fovea (HP:0007750)2.07152822
79Aplasia/Hypoplasia of the fovea (HP:0008060)2.07152822
80Amblyopia (HP:0000646)2.05662721
81Slow progression (HP:0003677)2.05220630
82Choroideremia (HP:0001139)2.03327215
83Increased CSF lactate (HP:0002490)2.02234511
84Congenital stationary night blindness (HP:0007642)10.1116904
85Abolished electroretinogram (ERG) (HP:0000550)1.96664494
86Increased serum pyruvate (HP:0003542)1.96247480
87Pendular nystagmus (HP:0012043)1.93550180
88Abnormality of the anterior horn cell (HP:0006802)1.93110770
89Degeneration of anterior horn cells (HP:0002398)1.93110770
90Gait ataxia (HP:0002066)1.92260187
91Torticollis (HP:0000473)1.90811828
92Focal dystonia (HP:0004373)1.90779777
93Oligodactyly (hands) (HP:0001180)1.88448003
94Retinal dysplasia (HP:0007973)1.87578333
95Exercise-induced myalgia (HP:0003738)1.86509173
96Hyperventilation (HP:0002883)1.86058097
97Dysarthria (HP:0001260)1.84558767
98Syncope (HP:0001279)1.83613324
99Impaired social interactions (HP:0000735)1.83450177
100Abnormal social behavior (HP:0012433)1.83450177
101Athetosis (HP:0002305)1.82087115
102Impaired vibration sensation in the lower limbs (HP:0002166)1.81824452
103Abnormal EKG (HP:0003115)1.81629517
104Attenuation of retinal blood vessels (HP:0007843)1.81472254
105Lipid accumulation in hepatocytes (HP:0006561)1.80699005
106Supranuclear gaze palsy (HP:0000605)1.79399730
107Aplasia/Hypoplasia affecting the fundus (HP:0008057)1.78529924
108Abnormality of the fovea (HP:0000493)1.78397101
109Hypsarrhythmia (HP:0002521)1.78284117
110Neoplasm of the heart (HP:0100544)1.73551627
111Esotropia (HP:0000565)1.72714537
112Polyphagia (HP:0002591)1.72234699
113Absent rod-and cone-mediated responses on ERG (HP:0007688)1.71823335
114Poor eye contact (HP:0000817)1.70933530
115Hypoplastic nipples (HP:0002557)1.68972927
116Atrial fibrillation (HP:0005110)1.67512283
117Abnormality of glycolysis (HP:0004366)1.67011777
118Absent septum pellucidum (HP:0001331)1.66703208
119Abnormality of the lower motor neuron (HP:0002366)1.65647369
120Photophobia (HP:0000613)1.64972201
121Narrow nasal bridge (HP:0000446)1.64859219
122Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.64752546
123Cholelithiasis (HP:0001081)1.64737427
124Generalized myoclonic seizures (HP:0002123)1.63183770
125Ankle clonus (HP:0011448)1.62445905
126Aplasia/Hypoplasia of the macula (HP:0008059)1.61785173
127Increased intramyocellular lipid droplets (HP:0012240)1.60871797
128Abnormality of the septum pellucidum (HP:0007375)1.59446471
129Optic disc pallor (HP:0000543)1.59422408
130Annular pancreas (HP:0001734)1.58243824
131Intellectual disability, mild (HP:0001256)1.53358292
132Leukodystrophy (HP:0002415)1.53068318
133Exertional dyspnea (HP:0002875)1.52088660
134Epidermoid cyst (HP:0200040)1.51404365
135Distal lower limb amyotrophy (HP:0008944)1.44876107
136Skin nodule (HP:0200036)1.42640905
137Morphological abnormality of the pyramidal tract (HP:0002062)1.41817328
138Muscle abnormality related to mitochondrial dysfunction (HP:0003800)1.40648591
139Congenital onset (HP:0003577)1.40442584
140X-linked dominant inheritance (HP:0001423)1.35781548
141Prolonged bleeding time (HP:0003010)1.35055544
142Exercise intolerance (HP:0003546)1.35026975
143Heterochromia iridis (HP:0001100)1.34316557
144Abnormality of renal resorption (HP:0011038)1.32571164
145Urinary urgency (HP:0000012)1.29065989
146Aplasia involving bones of the upper limbs (HP:0009823)1.28646129
147Aplasia of the phalanges of the hand (HP:0009802)1.28646129
148Aplasia involving bones of the extremities (HP:0009825)1.28646129
149Progressive inability to walk (HP:0002505)1.27577358
150Respiratory failure (HP:0002878)1.25817743
151Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.25581917
152Decreased activity of mitochondrial respiratory chain (HP:0008972)1.25581917
153Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)1.25242168
154Increased muscle lipid content (HP:0009058)1.24265213
155Abnormality of lateral ventricle (HP:0030047)1.17305546
156Inability to walk (HP:0002540)1.15138436
157Xanthomatosis (HP:0000991)1.14009271
158Abnormality of the level of lipoprotein cholesterol (HP:0010979)1.13830231

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP3K128.34585528
2PBK4.62882782
3RIPK14.51641121
4NME13.66930392
5MYLK3.57381705
6PAK63.03007132
7PRPF4B2.96347071
8CAMKK22.73452415
9TAOK22.56379730
10ARAF2.56063127
11CSNK1G32.41144633
12MINK12.40943541
13NEK12.40724230
14STK382.40714904
15TTK2.38988265
16CSNK1G22.37486870
17PINK12.32307842
18CSNK1A1L2.30361503
19TESK12.26180071
20MAP3K42.24698224
21CDK32.12253889
22MAP2K71.99162722
23MARK11.91505604
24CSNK1G11.86862350
25PHKG21.71005880
26PHKG11.71005880
27CAMKK11.68361955
28DYRK1A1.64136770
29WNK11.56057418
30TNIK1.55858112
31PAK41.53597769
32IRAK11.50925929
33NTRK31.48965152
34PNCK1.46074982
35MAP3K131.44307945
36MAP3K91.42043021
37PRKCG1.34392599
38CLK11.33373282
39CAMK2D1.30078344
40DAPK21.25618024
41CAMK1G1.24554303
42NTRK21.20901003
43TNK21.20413122
44FES1.18663102
45STK38L1.17456427
46MAP2K41.16813681
47BRAF1.15610161
48MAPK71.14186602
49CAMK11.13648238
50DAPK11.13631150
51ILK1.08008090
52MAP4K21.06242989
53INSRR0.99473455
54SGK4940.98746064
55SGK2230.98746064
56PRKG10.97285094
57EIF2AK10.97116988
58CDK140.95562646
59CAMK1D0.91482371
60SIK20.91138196
61ERBB30.88404049
62MAP3K70.88370309
63CDK150.87706874
64PRKAA10.86213590
65CDK50.84603338
66MAP3K110.84444496
67CDK180.83058178
68CDK190.81585697
69PTK60.79937411
70CAMK2A0.79609243
71RIPK40.78785537
72PRKCH0.77737493
73EPHA40.77622431
74CDK11A0.75871985
75SIK30.74279643
76GRK50.74170422
77CSNK1A10.72927155
78CAMK2G0.71152354
79CAMK40.70293519
80TAF10.70145887
81PRKCA0.69267157
82DAPK30.68633323
83PRKG20.66936808
84ITK0.66625213
85MAPK130.66098739
86CASK0.65880450
87TRIM280.64874303
88UHMK10.64861535
89PRKACA0.63546750
90AKT30.62486310
91LIMK10.61534323
92PRKCZ0.60154913
93DYRK1B0.58195540
94FER0.57819184
95PRKCE0.56774763
96ROCK20.56655678
97PDK10.53204630
98WNK40.51452527
99CSNK1D0.50841331
100PRKDC0.50573266
101BMPR20.50402476
102KSR10.49827745
103MARK20.49522666
104STK110.49486226
105IRAK20.49101948
106MAPK120.49010836
107SGK20.48606327
108CDC42BPA0.48404563
109RPS6KA30.47199133
110PRKCB0.47157310
111MOS0.44026277
112KSR20.43795928
113CAMK2B0.43004553
114SIK10.42164463
115PLK40.41302885
116SRC0.41216314
117PKN10.40984626
118SCYL20.40811194
119PLK20.40346713
120MAPK100.39803054
121CHEK20.39670479
122STK160.39390656
123YES10.38798686
124OXSR10.38342034
125GRK10.37068108
126GSK3B0.36719827
127MST40.35513068
128RAF10.34066490
129FYN0.33779087
130PRKACG0.32506086
131PAK30.32495503
132MAPK80.31960210
133MAP3K10.31641138
134ALK0.31310095
135CSNK1E0.30717412
136MAPK10.30675872
137STK390.29640258
138BCR0.24293175
139CSF1R0.23411452
140BMPR1B0.22157745
141TSSK60.21600159
142LCK0.21115930
143FGR0.20563971
144RPS6KB10.20472431
145SGK10.19131922
146CCNB10.19109502
147ROCK10.19026536
148BTK0.18668328
149PRKCD0.18659467
150SYK0.17466911

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050334.96829916
2GABAergic synapse_Homo sapiens_hsa047274.07311277
3Retrograde endocannabinoid signaling_Homo sapiens_hsa047233.72594322
4Synaptic vesicle cycle_Homo sapiens_hsa047213.65873262
5Morphine addiction_Homo sapiens_hsa050323.59743271
6Taste transduction_Homo sapiens_hsa047423.10486522
7Glutamatergic synapse_Homo sapiens_hsa047243.00170686
8Circadian entrainment_Homo sapiens_hsa047132.98927246
9Olfactory transduction_Homo sapiens_hsa047402.42048861
10Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049642.32781498
11Long-term depression_Homo sapiens_hsa047302.31900523
12Salivary secretion_Homo sapiens_hsa049702.14094320
13Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.02931510
14Insulin secretion_Homo sapiens_hsa049111.96188778
15Circadian rhythm_Homo sapiens_hsa047101.95283999
16Dopaminergic synapse_Homo sapiens_hsa047281.91542329
17Parkinsons disease_Homo sapiens_hsa050121.88637286
18Cholinergic synapse_Homo sapiens_hsa047251.87339249
19Long-term potentiation_Homo sapiens_hsa047201.81451303
20Serotonergic synapse_Homo sapiens_hsa047261.75644967
21Renin secretion_Homo sapiens_hsa049241.53091193
22Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.52342830
23Aldosterone synthesis and secretion_Homo sapiens_hsa049251.51595055
24Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.47482418
25Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.45005302
26Cardiac muscle contraction_Homo sapiens_hsa042601.44206646
27Collecting duct acid secretion_Homo sapiens_hsa049661.39584945
28Huntingtons disease_Homo sapiens_hsa050161.38954554
29Phototransduction_Homo sapiens_hsa047441.36374568
30Oxytocin signaling pathway_Homo sapiens_hsa049211.36198169
31Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.30795818
32Calcium signaling pathway_Homo sapiens_hsa040201.30363635
33Gastric acid secretion_Homo sapiens_hsa049711.28930732
34Phosphatidylinositol signaling system_Homo sapiens_hsa040701.26236520
35Amphetamine addiction_Homo sapiens_hsa050311.21372444
36Type II diabetes mellitus_Homo sapiens_hsa049301.19078362
37Fructose and mannose metabolism_Homo sapiens_hsa000511.18221846
38Pancreatic secretion_Homo sapiens_hsa049721.13783615
39Renin-angiotensin system_Homo sapiens_hsa046141.11449576
40Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.09190957
41Gap junction_Homo sapiens_hsa045401.05473731
42Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.02158100
43cGMP-PKG signaling pathway_Homo sapiens_hsa040220.99800819
44Inositol phosphate metabolism_Homo sapiens_hsa005620.96909321
45Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.91136836
46Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.90631991
47Dilated cardiomyopathy_Homo sapiens_hsa054140.88201019
48Carbohydrate digestion and absorption_Homo sapiens_hsa049730.86934084
49Glycerolipid metabolism_Homo sapiens_hsa005610.84187689
50GnRH signaling pathway_Homo sapiens_hsa049120.79859659
51cAMP signaling pathway_Homo sapiens_hsa040240.79764482
52Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.77574697
53Thyroid hormone synthesis_Homo sapiens_hsa049180.74931321
54Mineral absorption_Homo sapiens_hsa049780.72836852
55Vascular smooth muscle contraction_Homo sapiens_hsa042700.72056096
56Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.64602853
57Biosynthesis of amino acids_Homo sapiens_hsa012300.63888569
58Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.60467899
59Phospholipase D signaling pathway_Homo sapiens_hsa040720.60338032
60Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.58123955
61Estrogen signaling pathway_Homo sapiens_hsa049150.57296355
62Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.56651557
63Alcoholism_Homo sapiens_hsa050340.55501609
64Cocaine addiction_Homo sapiens_hsa050300.55413770
65Fatty acid biosynthesis_Homo sapiens_hsa000610.52990516
66Platelet activation_Homo sapiens_hsa046110.52289173
67Bile secretion_Homo sapiens_hsa049760.50651377
68Central carbon metabolism in cancer_Homo sapiens_hsa052300.49073230
69Vibrio cholerae infection_Homo sapiens_hsa051100.48789663
70Pyruvate metabolism_Homo sapiens_hsa006200.46531055
71mTOR signaling pathway_Homo sapiens_hsa041500.46406264
72Fatty acid elongation_Homo sapiens_hsa000620.46152960
73MAPK signaling pathway_Homo sapiens_hsa040100.43457354
74Choline metabolism in cancer_Homo sapiens_hsa052310.43204660
75Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.41136618
76African trypanosomiasis_Homo sapiens_hsa051430.40637094
77Thyroid hormone signaling pathway_Homo sapiens_hsa049190.39956158
78Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.37880570
79Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.36909951
80Alzheimers disease_Homo sapiens_hsa050100.36546371
81Regulation of autophagy_Homo sapiens_hsa041400.35110876
82Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.34597098
83Glioma_Homo sapiens_hsa052140.33871568
84ErbB signaling pathway_Homo sapiens_hsa040120.33614528
85Sphingolipid signaling pathway_Homo sapiens_hsa040710.33303907
86Arginine biosynthesis_Homo sapiens_hsa002200.32764604
87Protein export_Homo sapiens_hsa030600.32019209
88Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.31851723
89Melanogenesis_Homo sapiens_hsa049160.31147232
90Sphingolipid metabolism_Homo sapiens_hsa006000.30974795
91Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.29736406
92Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.28839228
93Rheumatoid arthritis_Homo sapiens_hsa053230.28686112
94Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.27399229
95Chemokine signaling pathway_Homo sapiens_hsa040620.27179603
96Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.26295699
97Glucagon signaling pathway_Homo sapiens_hsa049220.26082620
98Ras signaling pathway_Homo sapiens_hsa040140.23648713
99HIF-1 signaling pathway_Homo sapiens_hsa040660.20639178
100Prion diseases_Homo sapiens_hsa050200.20532247
101Axon guidance_Homo sapiens_hsa043600.19406014
102Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.19250587
103Pentose phosphate pathway_Homo sapiens_hsa000300.19149558
104Nitrogen metabolism_Homo sapiens_hsa009100.18798164
105Oxidative phosphorylation_Homo sapiens_hsa001900.17638829
106Oocyte meiosis_Homo sapiens_hsa041140.17597575
107Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.16580365
108Wnt signaling pathway_Homo sapiens_hsa043100.16436321
109Renal cell carcinoma_Homo sapiens_hsa052110.14054368
110VEGF signaling pathway_Homo sapiens_hsa043700.13713866
111Endocytosis_Homo sapiens_hsa041440.13525717
112Non-small cell lung cancer_Homo sapiens_hsa052230.13354761
113Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.13231089
114Rap1 signaling pathway_Homo sapiens_hsa040150.12169243
115Glycerophospholipid metabolism_Homo sapiens_hsa005640.12066472
116Carbon metabolism_Homo sapiens_hsa012000.12031147
117Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.07544908
118ABC transporters_Homo sapiens_hsa020100.07486406
119Dorso-ventral axis formation_Homo sapiens_hsa043200.07407492
120Leukocyte transendothelial migration_Homo sapiens_hsa046700.06164782
121Retinol metabolism_Homo sapiens_hsa008300.02926945
122Primary bile acid biosynthesis_Homo sapiens_hsa001200.02417863
123Fatty acid metabolism_Homo sapiens_hsa012120.02297532
124Metabolic pathways_Homo sapiens_hsa011000.00563833
125PPAR signaling pathway_Homo sapiens_hsa033200.00464600
126Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072-0.0185849
127Butanoate metabolism_Homo sapiens_hsa00650-0.0108483
128Phenylalanine metabolism_Homo sapiens_hsa00360-0.0093243

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