PCTP

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1L-phenylalanine catabolic process (GO:0006559)7.30777618
2erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)7.30777618
3L-phenylalanine metabolic process (GO:0006558)7.06790703
4erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)7.06790703
5aromatic amino acid family catabolic process (GO:0009074)6.62750432
6triglyceride-rich lipoprotein particle remodeling (GO:0034370)6.37469272
7protoporphyrinogen IX biosynthetic process (GO:0006782)6.30702033
8N-acetylneuraminate metabolic process (GO:0006054)6.10975596
9protoporphyrinogen IX metabolic process (GO:0046501)6.03752623
10tryptophan catabolic process (GO:0006569)6.01263900
11indole-containing compound catabolic process (GO:0042436)6.01263900
12indolalkylamine catabolic process (GO:0046218)6.01263900
13kynurenine metabolic process (GO:0070189)5.81719809
14cellular extravasation (GO:0045123)5.77950973
15bile acid biosynthetic process (GO:0006699)5.76817970
16alpha-linolenic acid metabolic process (GO:0036109)5.75496505
17tryptophan metabolic process (GO:0006568)5.71512549
18glyoxylate metabolic process (GO:0046487)5.67575600
19high-density lipoprotein particle remodeling (GO:0034375)5.56829214
20urea metabolic process (GO:0019627)5.46664635
21urea cycle (GO:0000050)5.46664635
22negative regulation of fibrinolysis (GO:0051918)5.35485066
23sulfur amino acid catabolic process (GO:0000098)5.23875018
24cysteine metabolic process (GO:0006534)5.23306224
25protein carboxylation (GO:0018214)5.13585598
26peptidyl-glutamic acid carboxylation (GO:0017187)5.13585598
27regulation of fibrinolysis (GO:0051917)5.10815704
28serine family amino acid catabolic process (GO:0009071)5.10429971
29nitrogen cycle metabolic process (GO:0071941)5.04988243
30killing of cells in other organism involved in symbiotic interaction (GO:0051883)5.00995226
31disruption of cells of other organism involved in symbiotic interaction (GO:0051818)5.00995226
32regulation of cholesterol esterification (GO:0010872)4.98313259
33fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)4.96270523
34bile acid metabolic process (GO:0008206)4.94221783
35aromatic amino acid family metabolic process (GO:0009072)4.84182856
36reverse cholesterol transport (GO:0043691)4.84051210
37plasma lipoprotein particle remodeling (GO:0034369)4.79256267
38protein-lipid complex remodeling (GO:0034368)4.79256267
39macromolecular complex remodeling (GO:0034367)4.79256267
40regulation of triglyceride catabolic process (GO:0010896)4.77705237
41complement activation, alternative pathway (GO:0006957)4.77419632
42amino-acid betaine metabolic process (GO:0006577)4.72904871
43regulation of protein activation cascade (GO:2000257)4.72610140
44phospholipid efflux (GO:0033700)4.70167612
45tyrosine metabolic process (GO:0006570)4.64592888
46glycine metabolic process (GO:0006544)4.58371794
47negative regulation of sterol transport (GO:0032372)4.55647083
48negative regulation of cholesterol transport (GO:0032375)4.55647083
49homocysteine metabolic process (GO:0050667)4.55526954
50alpha-amino acid catabolic process (GO:1901606)4.52247686
51lysine metabolic process (GO:0006553)4.47185398
52lysine catabolic process (GO:0006554)4.47185398
53triglyceride homeostasis (GO:0070328)4.46445360
54acylglycerol homeostasis (GO:0055090)4.46445360
55plasma lipoprotein particle clearance (GO:0034381)4.40929394
56regulation of complement activation (GO:0030449)4.37380537
57aldehyde catabolic process (GO:0046185)4.37162478
58cellular ketone body metabolic process (GO:0046950)4.33925682
59indolalkylamine metabolic process (GO:0006586)4.28516324
60serine family amino acid metabolic process (GO:0009069)4.25602923
61imidazole-containing compound metabolic process (GO:0052803)4.25466565
62positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)4.25261720
63bile acid and bile salt transport (GO:0015721)4.24143912
64regulation of MHC class II biosynthetic process (GO:0045346)4.23541178
65amine catabolic process (GO:0009310)4.20811040
66cellular biogenic amine catabolic process (GO:0042402)4.20811040
67cholesterol efflux (GO:0033344)4.19668453
68serine family amino acid biosynthetic process (GO:0009070)4.15381874
69cellular amino acid catabolic process (GO:0009063)4.14657585
70coenzyme catabolic process (GO:0009109)4.13359642
71low-density lipoprotein particle remodeling (GO:0034374)4.10687979
72plasma lipoprotein particle assembly (GO:0034377)4.08760537
73benzene-containing compound metabolic process (GO:0042537)4.07024127
74neutrophil activation involved in immune response (GO:0002283)4.04093945
75ethanol oxidation (GO:0006069)4.01557289
76cellular glucuronidation (GO:0052695)4.00728018
77amino sugar catabolic process (GO:0046348)3.96377003
78blood coagulation, intrinsic pathway (GO:0007597)3.94693296
79cellular modified amino acid catabolic process (GO:0042219)3.93920085
80glutamate metabolic process (GO:0006536)3.91085897
81drug catabolic process (GO:0042737)3.89761319
82microglial cell activation (GO:0001774)3.87995031
83positive regulation of lipoprotein lipase activity (GO:0051006)3.86521571
84positive regulation of triglyceride lipase activity (GO:0061365)3.86521571
85arginine metabolic process (GO:0006525)3.86290430
86fibrinolysis (GO:0042730)3.81164068
87NAD biosynthetic process (GO:0009435)3.79955340
88cofactor catabolic process (GO:0051187)3.79749940
89epoxygenase P450 pathway (GO:0019373)3.78348983
90very-low-density lipoprotein particle assembly (GO:0034379)3.77045755
91ketone body metabolic process (GO:1902224)3.74515959
92pyridine nucleotide biosynthetic process (GO:0019363)3.72727588
93nicotinamide nucleotide biosynthetic process (GO:0019359)3.72727588
94carboxylic acid catabolic process (GO:0046395)3.72317740
95organic acid catabolic process (GO:0016054)3.72317740
96cholesterol homeostasis (GO:0042632)3.71873106
97dicarboxylic acid biosynthetic process (GO:0043650)3.71750819
98negative regulation of lipase activity (GO:0060192)3.70870908
99plasma lipoprotein particle organization (GO:0071827)3.69731795
100exogenous drug catabolic process (GO:0042738)3.67635382
101positive regulation of lipid catabolic process (GO:0050996)3.66286582
102phospholipid homeostasis (GO:0055091)3.65822888
103positive regulation of histone deacetylation (GO:0031065)3.65754404
104sterol homeostasis (GO:0055092)3.65528914
105short-chain fatty acid metabolic process (GO:0046459)3.65104397
106protein-lipid complex assembly (GO:0065005)3.61986070
107uronic acid metabolic process (GO:0006063)3.60059886
108glucuronate metabolic process (GO:0019585)3.60059886
109carnitine metabolic process (GO:0009437)3.58076049
110reactive oxygen species biosynthetic process (GO:1903409)3.54624159
111flavonoid metabolic process (GO:0009812)3.54095146
112protein activation cascade (GO:0072376)3.53853155
113response to nitrosative stress (GO:0051409)3.51011208
114modulation of growth of symbiont involved in interaction with host (GO:0044144)3.48365106
115regulation of growth of symbiont in host (GO:0044126)3.48365106
116negative regulation of growth of symbiont in host (GO:0044130)3.48365106
117negative regulation of growth of symbiont involved in interaction with host (GO:0044146)3.48365106
118monocarboxylic acid catabolic process (GO:0072329)3.47868889
119regulation of bile acid biosynthetic process (GO:0070857)3.46593565
120omega-hydroxylase P450 pathway (GO:0097267)3.44960579
121neutrophil mediated immunity (GO:0002446)3.26617682
122heme biosynthetic process (GO:0006783)3.22809091
123heme metabolic process (GO:0042168)3.12906984
124positive regulation of chemokine biosynthetic process (GO:0045080)3.06571233
125purine deoxyribonucleotide catabolic process (GO:0009155)3.06558459
126regulation of tumor necrosis factor biosynthetic process (GO:0042534)3.04455406
127positive regulation of hemostasis (GO:1900048)2.96058112
128positive regulation of blood coagulation (GO:0030194)2.96058112
129S-adenosylmethionine metabolic process (GO:0046500)2.95033900
130positive regulation of protein deacetylation (GO:0090312)2.93381978
131thrombin receptor signaling pathway (GO:0070493)2.92774541
132deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.91790580
133modulation by organism of defense response of other organism involved in symbiotic interaction (GO:02.90316640
134positive regulation by organism of defense response of other organism involved in symbiotic interact2.90316640
135modulation by symbiont of host immune response (GO:0052553)2.90316640
136positive regulation by symbiont of host defense response (GO:0052509)2.90316640
137modulation by symbiont of host defense response (GO:0052031)2.90316640
138modulation by organism of immune response of other organism involved in symbiotic interaction (GO:002.90316640
139regulation of chemokine biosynthetic process (GO:0045073)2.88943633
140positive regulation of gamma-delta T cell activation (GO:0046645)2.88269973
141negative regulation of fatty acid biosynthetic process (GO:0045717)2.87872725
142centriole replication (GO:0007099)2.87002986
143positive regulation of coagulation (GO:0050820)2.84879607
144positive regulation of interleukin-8 biosynthetic process (GO:0045416)2.83926242
145negative regulation of phagocytosis (GO:0050765)2.81077213
146negative regulation of protein activation cascade (GO:2000258)2.79276212
147porphyrin-containing compound metabolic process (GO:0006778)2.76430221
148disruption of cells of other organism (GO:0044364)2.76192472
149killing of cells of other organism (GO:0031640)2.76192472
150macrophage activation (GO:0042116)2.70181844
151leukocyte migration involved in inflammatory response (GO:0002523)2.64630391
152response to peptidoglycan (GO:0032494)2.62148457
153neutrophil activation (GO:0042119)2.59286243
154protein-lipid complex subunit organization (GO:0071825)2.58471638
155respiratory burst (GO:0045730)2.56030975
156porphyrin-containing compound biosynthetic process (GO:0006779)2.54754889
157negative regulation of hemostasis (GO:1900047)2.54378512
158negative regulation of blood coagulation (GO:0030195)2.54378512
159negative regulation of leukocyte mediated cytotoxicity (GO:0001911)2.50311149
160negative regulation of cell killing (GO:0031342)2.50311149
161base-excision repair, AP site formation (GO:0006285)2.49336424

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1* RXR_22158963_ChIP-Seq_LIVER_Mouse8.03639483
2* PPARA_22158963_ChIP-Seq_LIVER_Mouse6.97599898
3* EGR1_23403033_ChIP-Seq_LIVER_Mouse6.85072316
4* LXR_22158963_ChIP-Seq_LIVER_Mouse6.09434650
5CEBPA_23403033_ChIP-Seq_LIVER_Mouse5.20939117
6FOXO1_23066095_ChIP-Seq_LIVER_Mouse4.98364810
7PPARG_19300518_ChIP-PET_3T3-L1_Mouse4.92310163
8CEBPB_23403033_ChIP-Seq_LIVER_Mouse4.18846414
9NR1I2_20693526_ChIP-Seq_LIVER_Mouse3.52429380
10BP1_19119308_ChIP-ChIP_Hs578T_Human2.48268482
11HNF4A_19761587_ChIP-ChIP_CACO-2_Human2.15635012
12GATA1_19941826_ChIP-Seq_K562_Human2.15408528
13SPI1_23547873_ChIP-Seq_NB4_Human2.07049242
14SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.04099263
15TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse2.01483416
16* ESR1_17901129_ChIP-ChIP_LIVER_Mouse11.3914220
17IRF8_22096565_ChIP-ChIP_GC-B_Human1.97903038
18TCF7L2_21901280_ChIP-Seq_H4IIE_Rat1.96621089
19SPI1_23127762_ChIP-Seq_K562_Human1.91510486
20SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.90345700
21GATA1_22025678_ChIP-Seq_K562_Human1.75635840
22MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.68403325
23SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.58040841
24IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.55616564
25* NCOR1_26117541_ChIP-Seq_K562_Human1.51997015
26* STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.49492422
27CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.47888638
28VDR_24763502_ChIP-Seq_THP-1_Human1.45730974
29STAT4_19710469_ChIP-ChIP_TH1__Mouse1.42992245
30E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.42533347
31GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.40519031
32TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.39382171
33HTT_18923047_ChIP-ChIP_STHdh_Human1.39053223
34HOXB4_20404135_ChIP-ChIP_EML_Mouse1.37529642
35GATA2_21666600_ChIP-Seq_HMVEC_Human1.36377295
36RUNX1_22412390_ChIP-Seq_EML_Mouse1.35755666
37* HNF4A_19822575_ChIP-Seq_HepG2_Human1.30789053
38STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.30693876
39MYB_26560356_Chip-Seq_TH1_Human1.29102825
40SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.28265763
41SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.28228410
42MYB_26560356_Chip-Seq_TH2_Human1.26494439
43RXRA_24833708_ChIP-Seq_LIVER_Mouse1.25300885
44TFEB_21752829_ChIP-Seq_HELA_Human1.23654617
45* FOXA2_19822575_ChIP-Seq_HepG2_Human1.23416468
46VDR_21846776_ChIP-Seq_THP-1_Human1.22286483
47IRF1_19129219_ChIP-ChIP_H3396_Human1.21952335
48MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.21762120
49CLOCK_20551151_ChIP-Seq_293T_Human1.21663388
50MAF_26560356_Chip-Seq_TH1_Human1.20042495
51GATA3_26560356_Chip-Seq_TH2_Human1.13082274
52TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.12492779
53ESR1_20079471_ChIP-ChIP_T-47D_Human1.10925724
54PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.08990516
55THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.08514439
56NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.07920214
57EGR1_19374776_ChIP-ChIP_THP-1_Human1.04752328
58ELF1_20517297_ChIP-Seq_JURKAT_Human0.97514872
59FOXP3_17237761_ChIP-ChIP_TREG_Mouse0.96384404
60PU_27001747_Chip-Seq_BMDM_Mouse0.95745979
61TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse0.94849043
62RUNX_20019798_ChIP-Seq_JUKART_Human0.92579416
63GATA3_27048872_Chip-Seq_THYMUS_Human0.92331064
64* Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.91453533
65ERG_20887958_ChIP-Seq_HPC-7_Mouse0.90921995
66UTX_26944678_Chip-Seq_JUKART_Human0.90366551
67ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.89464286
68IRF8_21731497_ChIP-ChIP_J774_Mouse0.89381211
69RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.88256433
70PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.88107426
71YY1_22570637_ChIP-Seq_MALME-3M_Human0.87888380
72ESR1_15608294_ChIP-ChIP_MCF-7_Human0.87259154
73* RUNX1_20887958_ChIP-Seq_HPC-7_Mouse0.86977487
74IKZF1_21737484_ChIP-ChIP_HCT116_Human0.86877325
75ELF1_17652178_ChIP-ChIP_JURKAT_Human0.86623313
76SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.86288775
77IRF8_22096565_ChIP-ChIP_GC-B_Mouse0.86217513
78SOX2_27498859_Chip-Seq_STOMACH_Mouse0.84266497
79* GATA4_25053715_ChIP-Seq_YYC3_Human0.84071079
80KAP1_22055183_ChIP-Seq_ESCs_Mouse0.83610505
81SCL_19346495_ChIP-Seq_HPC-7_Human0.83470590
82* NANOG_20526341_ChIP-Seq_ESCs_Human0.83161863
83FOXP3_21729870_ChIP-Seq_TREG_Human0.82946883
84STAT3_20064451_ChIP-Seq_CD4+T_Mouse0.81364280
85RARA_24833708_ChIP-Seq_LIVER_Mouse0.81043794
86ETS1_22383799_ChIP-Seq_G1ME_Mouse0.80600711
87ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.80538341
88NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse0.80255983
89STAT3_1855785_ChIP-Seq_MESCs_Mouse0.78882745
90BRD4_27068464_Chip-Seq_AML-cells_Mouse0.76745396
91SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse0.75875998
92SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.75156549
93CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.71814637
94GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.71804555
95E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse0.71676890
96IRF8_27001747_Chip-Seq_BMDM_Mouse0.71298096
97EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse0.70867295
98BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.68884926
99* AUTS2_25519132_ChIP-Seq_293T-REX_Human0.68211486
100RARB_24833708_ChIP-Seq_LIVER_Mouse0.67123704
101RARG_19884340_ChIP-ChIP_MEFs_Mouse0.65064944
102GATA1_19941827_ChIP-Seq_MEL_Mouse0.63921398
103GATA1_22383799_ChIP-Seq_G1ME_Mouse0.63365240
104PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.63043897
105MYB_21317192_ChIP-Seq_ERMYB_Mouse0.62987815
106CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.62833282
107PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.62421453
108LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.62312171
109GATA2_22383799_ChIP-Seq_G1ME_Mouse0.62299683
110AR_20517297_ChIP-Seq_VCAP_Human0.61434964
111SRF_21415370_ChIP-Seq_HL-1_Mouse0.59445489
112* CEBPB_22108803_ChIP-Seq_LS180_Human0.59417457
113NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.59187177
114RAD21_21589869_ChIP-Seq_MESCs_Mouse0.58982709
115ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.57284615
116* LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.56678529
117PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.55788738
118EGR1_19032775_ChIP-ChIP_M12_Human0.55302990
119FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.53430617
120LXR_22292898_ChIP-Seq_THP-1_Human0.53052188
121PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.52966576
122CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.50160027
123ESET_19884257_ChIP-Seq_ESCs_Mouse0.49906823
124SALL4_18804426_ChIP-ChIP_XEN_Mouse0.49861574
125PPARG_20887899_ChIP-Seq_3T3-L1_Mouse0.48462683
126* FOXA1_26743006_Chip-Seq_LNCaP-abl_Human0.47857906
127FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.47838678
128CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse0.47440015
129P53_21459846_ChIP-Seq_SAOS-2_Human0.47313855
130GATA6_25053715_ChIP-Seq_YYC3_Human0.46555528
131STAT1_17558387_ChIP-Seq_HELA_Human0.46142772
132BCL6_27268052_Chip-Seq_Bcells_Human0.45311111
133* CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.45113689
134PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.44833159
135BCOR_27268052_Chip-Seq_Bcells_Human0.44730457
136SPI1_20517297_ChIP-Seq_HL60_Human0.43910198
137* SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.43854083
138AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.43854040
139CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.43613889
140GATA2_19941826_ChIP-Seq_K562_Human0.42178494
141P300_27268052_Chip-Seq_Bcells_Human0.42027103
142MECOM_23826213_ChIP-Seq_KASUMI_Mouse0.41996846
143TAF2_19829295_ChIP-Seq_ESCs_Human0.41900084
144MYC_19915707_ChIP-ChIP_AK7_Human0.41136560
145SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.40596215
146SPI1_26923725_Chip-Seq_HPCs_Mouse0.40497933

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002139_abnormal_hepatobiliary_system8.21846527
2MP0005360_urolithiasis7.16949200
3* MP0005085_abnormal_gallbladder_physiolo6.02482955
4* MP0005365_abnormal_bile_salt5.92825843
5MP0008875_abnormal_xenobiotic_pharmacok5.02134496
6MP0003806_abnormal_nucleotide_metabolis4.13012564
7* MP0003252_abnormal_bile_duct3.52684164
8MP0010329_abnormal_lipoprotein_level3.46152288
9MP0009840_abnormal_foam_cell3.40370721
10MP0003195_calcinosis2.70084633
11MP0005332_abnormal_amino_acid2.66978934
12MP0001666_abnormal_nutrient_absorption2.52612967
13MP0003191_abnormal_cellular_cholesterol2.46724237
14MP0003303_peritoneal_inflammation2.35226429
15* MP0005083_abnormal_biliary_tract2.27477179
16MP0002138_abnormal_hepatobiliary_system2.26815356
17MP0004019_abnormal_vitamin_homeostasis2.17654880
18MP0000609_abnormal_liver_physiology2.17511607
19* MP0002118_abnormal_lipid_homeostasis2.00651388
20MP0005319_abnormal_enzyme/_coenzyme1.89650234
21MP0003868_abnormal_feces_composition1.84319250
22MP0009697_abnormal_copulation1.81228760
23MP0005451_abnormal_body_composition1.78538856
24MP0001764_abnormal_homeostasis1.77572543
25MP0008004_abnormal_stomach_pH1.68625654
26MP0005167_abnormal_blood-brain_barrier1.66062930
27MP0000465_gastrointestinal_hemorrhage1.64434494
28MP0003186_abnormal_redox_activity1.59393331
29MP0005584_abnormal_enzyme/coenzyme_acti1.57488704
30MP0005000_abnormal_immune_tolerance1.44333557
31MP0003011_delayed_dark_adaptation1.43849889
32MP0005671_abnormal_response_to1.42285659
33MP0002148_abnormal_hypersensitivity_rea1.41605648
34MP0008058_abnormal_DNA_repair1.41188536
35* MP0002452_abnormal_antigen_presenting1.38240510
36MP0002723_abnormal_immune_serum1.37188576
37MP0003656_abnormal_erythrocyte_physiolo1.36275252
38MP0009643_abnormal_urine_homeostasis1.32760566
39MP0000343_altered_response_to1.30775987
40MP0009764_decreased_sensitivity_to1.30417910
41* MP0001819_abnormal_immune_cell1.30004503
42* MP0002420_abnormal_adaptive_immunity1.29342922
43* MP0000598_abnormal_liver_morphology1.25002424
44MP0001790_abnormal_immune_system1.24867756
45MP0005387_immune_system_phenotype1.24867756
46MP0003172_abnormal_lysosome_physiology1.21792016
47MP0008961_abnormal_basal_metabolism1.19785080
48MP0005397_hematopoietic_system_phenotyp1.16957238
49MP0001545_abnormal_hematopoietic_system1.16957238
50MP0008469_abnormal_protein_level1.12806608
51MP0009763_increased_sensitivity_to1.12376086
52MP0003828_pulmonary_edema1.11824669
53MP0009333_abnormal_splenocyte_physiolog1.10085154
54MP0005647_abnormal_sex_gland1.09665768
55MP0001533_abnormal_skeleton_physiology1.09497279
56MP0002398_abnormal_bone_marrow1.09489789
57MP0002722_abnormal_immune_system1.08424795
58MP0004147_increased_porphyrin_level1.03044588
59MP0005464_abnormal_platelet_physiology1.01127619
60MP0000716_abnormal_immune_system1.00913173
61MP0002429_abnormal_blood_cell1.00215182
62MP0004043_abnormal_pH_regulation1.00192078
63MP0002254_reproductive_system_inflammat0.98672643
64MP0006036_abnormal_mitochondrial_physio0.98109267
65MP0003436_decreased_susceptibility_to0.97571520
66MP0000604_amyloidosis0.96331537
67MP0005636_abnormal_mineral_homeostasis0.95046098
68MP0002405_respiratory_system_inflammati0.93067773
69MP0009642_abnormal_blood_homeostasis0.91170144
70MP0005408_hypopigmentation0.90647742
71MP0008260_abnormal_autophagy0.90182728
72MP0003724_increased_susceptibility_to0.86388567
73MP0009765_abnormal_xenobiotic_induced0.86045248
74MP0005310_abnormal_salivary_gland0.85949281
75MP0005084_abnormal_gallbladder_morpholo0.84337405
76MP0003221_abnormal_cardiomyocyte_apopto0.82262670
77MP0005376_homeostasis/metabolism_phenot0.81984954
78MP0006054_spinal_hemorrhage0.80731503
79MP0010368_abnormal_lymphatic_system0.80198505
80MP0005220_abnormal_exocrine_pancreas0.79263928
81MP0000015_abnormal_ear_pigmentation0.78220994
82MP0005164_abnormal_response_to0.77943597
83MP0003705_abnormal_hypodermis_morpholog0.75791571
84MP0002078_abnormal_glucose_homeostasis0.71053594
85MP0001663_abnormal_digestive_system0.69130060
86MP0005058_abnormal_lysosome_morphology0.68906324
87MP0005334_abnormal_fat_pad0.68087533
88MP0002876_abnormal_thyroid_physiology0.67830330
89MP0005266_abnormal_metabolism0.67279193
90MP0005670_abnormal_white_adipose0.64880748
91MP0009785_altered_susceptibility_to0.63417718
92MP0006035_abnormal_mitochondrial_morpho0.63168697
93MP0002971_abnormal_brown_adipose0.62914513
94MP0002928_abnormal_bile_duct0.61713840
95MP0004782_abnormal_surfactant_physiolog0.61585974
96MP0006082_CNS_inflammation0.61570318
97MP0001853_heart_inflammation0.61502305
98MP0001756_abnormal_urination0.59389541
99MP0002136_abnormal_kidney_physiology0.59015658
100MP0001845_abnormal_inflammatory_respons0.58487675
101MP0001835_abnormal_antigen_presentation0.56919705
102MP0005025_abnormal_response_to0.56415807
103MP0008873_increased_physiological_sensi0.54972302
104MP0005535_abnormal_body_temperature0.53751634
105MP0003638_abnormal_response/metabolism_0.53344151
106* MP0002419_abnormal_innate_immunity0.52945096
107MP0009053_abnormal_anal_canal0.51597303
108MP0004130_abnormal_muscle_cell0.51515164
109MP0000639_abnormal_adrenal_gland0.51132104
110MP0001661_extended_life_span0.50506882
111MP0005448_abnormal_energy_balance0.49165290
112MP0003718_maternal_effect0.48912276
113MP0000685_abnormal_immune_system0.48245035
114MP0005075_abnormal_melanosome_morpholog0.46560379
115MP0002132_abnormal_respiratory_system0.44193774
116MP0005395_other_phenotype0.43426501
117MP0003690_abnormal_glial_cell0.43295473
118MP0000249_abnormal_blood_vessel0.42051753
119MP0003075_altered_response_to0.41974057
120MP0008874_decreased_physiological_sensi0.41176843
121MP0009115_abnormal_fat_cell0.39808509
122MP0008872_abnormal_physiological_respon0.38840525
123MP0003300_gastrointestinal_ulcer0.37911627
124MP0004947_skin_inflammation0.36766611
125MP0005166_decreased_susceptibility_to0.36628831
126MP0004381_abnormal_hair_follicle0.36031707
127MP0001800_abnormal_humoral_immune0.35482534
128MP0010155_abnormal_intestine_physiology0.35463242
129MP0003953_abnormal_hormone_level0.34938094
130MP0009672_abnormal_birth_weight0.33451249
131MP0001243_abnormal_dermal_layer0.33013434
132MP0002970_abnormal_white_adipose0.32086367
133MP0002135_abnormal_kidney_morphology0.29145090
134MP0005666_abnormal_adipose_tissue0.27299508
135MP0000689_abnormal_spleen_morphology0.27218871
136MP0002796_impaired_skin_barrier0.27190381

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of aromatic amino acid family metabolism (HP:0004338)7.38702387
2Intrahepatic cholestasis (HP:0001406)6.89073101
3Deep venous thrombosis (HP:0002625)6.80286908
4Abnormality of monocarboxylic acid metabolism (HP:0010996)6.44808155
5Prolonged partial thromboplastin time (HP:0003645)6.22000413
6Hypobetalipoproteinemia (HP:0003563)6.17393851
7Xanthomatosis (HP:0000991)5.99003771
8Hyperlipoproteinemia (HP:0010980)5.30382361
9Joint hemorrhage (HP:0005261)4.89398260
10Hypolipoproteinemia (HP:0010981)4.55753480
11Hyperammonemia (HP:0001987)4.54097300
12Complement deficiency (HP:0004431)4.52066820
13Prolonged bleeding time (HP:0003010)4.39516792
14Epidermoid cyst (HP:0200040)4.31937987
15Abnormality of methionine metabolism (HP:0010901)4.19830173
16Abnormality of the level of lipoprotein cholesterol (HP:0010979)4.19654280
17Abnormality of the common coagulation pathway (HP:0010990)4.14083673
18Hyperglycinemia (HP:0002154)4.11847078
19Ketosis (HP:0001946)4.11217793
20Abnormality of sulfur amino acid metabolism (HP:0004339)4.10958001
21Abnormality of pyrimidine metabolism (HP:0004353)4.10169485
22Petechiae (HP:0000967)4.08603682
23Abnormality of aspartate family amino acid metabolism (HP:0010899)4.07170761
24Epistaxis (HP:0000421)4.05793318
25Abnormality of glutamine family amino acid metabolism (HP:0010902)4.01397281
26Hypoalphalipoproteinemia (HP:0003233)3.94491406
27Fat malabsorption (HP:0002630)3.92184038
28Hypoglycemic coma (HP:0001325)3.89768727
29Recurrent abscess formation (HP:0002722)3.84401776
30Purpura (HP:0000979)3.83892012
31Hyperglycinuria (HP:0003108)3.81695325
32Abnormality of glycine metabolism (HP:0010895)3.73175471
33Abnormality of serine family amino acid metabolism (HP:0010894)3.73175471
34Abnormal platelet volume (HP:0011876)3.64734073
35Abnormality of the intrinsic pathway (HP:0010989)3.63120642
36Hypercholesterolemia (HP:0003124)3.56931073
37Recurrent bacterial skin infections (HP:0005406)3.56284841
38Abnormality of fatty-acid metabolism (HP:0004359)3.47537713
39Obstructive lung disease (HP:0006536)3.47279816
40Chronic obstructive pulmonary disease (HP:0006510)3.47279816
41Conjugated hyperbilirubinemia (HP:0002908)3.45171485
42Hyperbilirubinemia (HP:0002904)3.43458479
43Abnormality of long-chain fatty-acid metabolism (HP:0010964)3.41518782
44Impaired platelet aggregation (HP:0003540)3.38617729
45Abnormal platelet function (HP:0011869)3.38617729
46Abnormality of complement system (HP:0005339)3.37457654
47Abnormality of nucleobase metabolism (HP:0010932)3.22289975
48Myositis (HP:0100614)3.13959319
49Eczematoid dermatitis (HP:0000976)3.13598108
50Abnormality of macrophages (HP:0004311)3.12405571
51Abnormality of serum amino acid levels (HP:0003112)3.02517037
52Steatorrhea (HP:0002570)3.02384599
53Delayed CNS myelination (HP:0002188)2.99937926
54Ketoacidosis (HP:0001993)2.90536410
55Hepatocellular carcinoma (HP:0001402)2.85576577
56Orchitis (HP:0100796)2.84092056
57Dicarboxylic aciduria (HP:0003215)2.82370275
58Abnormality of dicarboxylic acid metabolism (HP:0010995)2.82370275
59Metabolic acidosis (HP:0001942)2.81890814
60Abnormality of purine metabolism (HP:0004352)2.78350220
61Myocardial infarction (HP:0001658)2.76785689
62Optic neuritis (HP:0100653)2.74756379
63Retrobulbar optic neuritis (HP:0100654)2.74756379
64Vacuolated lymphocytes (HP:0001922)2.72662197
65Hypochromic microcytic anemia (HP:0004840)2.70250981
66Abnormality of the prostate (HP:0008775)2.70076274
67Systemic lupus erythematosus (HP:0002725)2.67844372
68Spontaneous hematomas (HP:0007420)2.66110133
69Spontaneous abortion (HP:0005268)2.63967148
70Lethargy (HP:0001254)2.62956264
71Hepatosplenomegaly (HP:0001433)2.61296732
72Abnormality of the heme biosynthetic pathway (HP:0010472)2.61102029
73Polycythemia (HP:0001901)2.59060866
74Gangrene (HP:0100758)2.58795835
75Arterial thrombosis (HP:0004420)2.57963459
76Glomerulonephritis (HP:0000099)2.56615051
77Generalized aminoaciduria (HP:0002909)2.52563131
78Recurrent gram-negative bacterial infections (HP:0005420)2.52055582
79Menorrhagia (HP:0000132)2.51211198
80Acanthocytosis (HP:0001927)2.50330296
81Skin nodule (HP:0200036)2.49864875
82Spastic diplegia (HP:0001264)2.45546348
83Vascular calcification (HP:0004934)2.43588888
84Anorexia (HP:0002039)2.43323630
85Gingival bleeding (HP:0000225)2.43239033
86Increased serum ferritin (HP:0003281)2.40049929
87Cerebral edema (HP:0002181)2.36357010
88Hypoglycemic seizures (HP:0002173)2.35088469
89Opisthotonus (HP:0002179)2.29338146
90Irritability (HP:0000737)2.27269554
91Abnormal gallbladder morphology (HP:0012437)2.26559503
92Pancreatitis (HP:0001733)2.24600326
93Chest pain (HP:0100749)2.24358551
94Gout (HP:0001997)2.22924460
95Amyloidosis (HP:0011034)2.21911076
96Stomatitis (HP:0010280)2.21027201
97Cutaneous photosensitivity (HP:0000992)2.20547450
98Cholelithiasis (HP:0001081)2.20547162
99Thrombophlebitis (HP:0004418)2.19765718
100Esophageal varix (HP:0002040)2.19224763
101Renal cortical cysts (HP:0000803)2.19003533
102Malnutrition (HP:0004395)2.18435933
103Meningitis (HP:0001287)2.16201140
104Recurrent skin infections (HP:0001581)2.15334615
105Neonatal onset (HP:0003623)2.14845045
106Joint swelling (HP:0001386)2.13845188
107Late onset (HP:0003584)2.12666159
108Vomiting (HP:0002013)2.12454708
109Abnormal gallbladder physiology (HP:0012438)2.12230435
110Cholecystitis (HP:0001082)2.12230435
111Poikilocytosis (HP:0004447)2.11796542
112Increased cerebral lipofuscin (HP:0011813)2.10246517
113Cardiovascular calcification (HP:0011915)2.09783016
114Brushfield spots (HP:0001088)2.09697689
115Nausea (HP:0002018)2.08561702
116Increased neuronal autofluorescent lipopigment (HP:0002074)2.07732737
117Hemoptysis (HP:0002105)2.07107937
118Mitral stenosis (HP:0001718)2.07049341
119Proximal tubulopathy (HP:0000114)2.01550642
120Urticaria (HP:0001025)2.00120724
121Reticulocytosis (HP:0001923)1.99586100
122Vasculitis (HP:0002633)1.99458146
123Abnormality of iron homeostasis (HP:0011031)1.99439142
124Episodic fever (HP:0001954)1.98725941
125Enlarged kidneys (HP:0000105)1.96779766
126Keratoconjunctivitis sicca (HP:0001097)1.96390275
127Abnormality of urine glucose concentration (HP:0011016)1.95589474
128Glycosuria (HP:0003076)1.95589474
129Elevated hepatic transaminases (HP:0002910)1.94961145
130Polyneuropathy (HP:0001271)1.94722478
131Abnormality of transition element cation homeostasis (HP:0011030)1.93704704
132Encephalitis (HP:0002383)1.91458781
133Sensorimotor neuropathy (HP:0007141)1.91248092
134Rickets (HP:0002748)1.89031384
135Abnormality of the gallbladder (HP:0005264)1.88528043
136Fair hair (HP:0002286)1.88217848
137Pulmonary infiltrates (HP:0002113)1.86765226
138Abnormality of the vasculature of the conjunctiva (HP:0008054)1.86601986
139Abnormal enzyme/coenzyme activity (HP:0012379)1.86468236
140Recurrent fungal infections (HP:0002841)1.84765039
141Hemorrhage of the eye (HP:0011885)1.84494485
142Abnormal cartilage morphology (HP:0002763)1.83981381
143Hydroxyprolinuria (HP:0003080)1.83688404
144Abnormality of proline metabolism (HP:0010907)1.83688404
145Hyperinsulinemic hypoglycemia (HP:0000825)1.82378007
146Increased mean platelet volume (HP:0011877)1.82301845
147Gastrointestinal infarctions (HP:0005244)1.82097461
148Keratoconjunctivitis (HP:0001096)1.81492343
149Generalized hyperpigmentation (HP:0007440)1.81429920
150Pulmonary embolism (HP:0002204)1.80003435
151Conjunctival telangiectasia (HP:0000524)1.77853431
152Paralysis (HP:0003470)1.77734297

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BCKDK6.74877505
2CCNB14.74178248
3ERN14.40105988
4NEK24.35800793
5SIK13.56115804
6FGFR43.53042258
7RIPK43.41479769
8TAOK33.34358616
9FLT32.78031998
10CAMKK22.52058485
11INSRR2.39859430
12PKN22.27967069
13TYK22.13375217
14TESK22.11931412
15SMG11.97318998
16MST1R1.80416304
17KDR1.78233382
18MAP2K31.76317772
19PIK3CG1.72904476
20MAPK111.69803008
21ERBB41.67658869
22NEK91.67504623
23TBK11.65486726
24IRAK31.63925611
25MAP3K141.63274279
26TAF11.55143057
27BLK1.50726838
28BMX1.46970115
29BMPR21.46251291
30ABL21.45960993
31VRK21.43723740
32MAP2K41.43141451
33CSF1R1.41330212
34FGR1.39105578
35MAP4K11.36550389
36TGFBR21.34492576
37MAP3K101.34424134
38FES1.33588150
39MAP4K21.22616847
40CAMK1G1.22545471
41KIT1.19322389
42PTK61.18711933
43FRK1.18549126
44MAP3K111.17323236
45GRK61.17240131
46JAK21.16124456
47MST41.15649984
48MAP2K61.14657216
49TNK21.09444230
50BTK1.06506143
51MAPK41.06356581
52TRIB31.04497616
53HCK1.03817734
54JAK31.03581168
55NUAK11.01998930
56IKBKE1.01714027
57NME21.01120078
58PTK2B0.95542332
59MAP3K30.90899734
60TIE10.90697942
61JAK10.90528761
62CLK10.90416871
63STK160.89098835
64PRPF4B0.88995202
65PRKAA20.88231387
66ACVR1B0.87045834
67CDK60.86945198
68TEC0.85603363
69CSK0.84717917
70CDK40.84527610
71GRK10.84023605
72TAOK20.83644013
73IRAK40.81127605
74MAP3K70.80059104
75ZAP700.79016573
76ARAF0.77087604
77YES10.73947688
78IKBKB0.73826837
79KSR20.72371068
80PAK40.70738173
81PINK10.69011024
82RAF10.67912119
83MAP3K10.67622035
84MAP3K20.66912004
85DYRK1B0.64415279
86MAPK150.62832319
87LYN0.61316784
88TGFBR10.60443230
89MAP3K60.59112114
90IRAK10.59096328
91ERBB20.58180871
92EIF2AK10.57600323
93PRKACG0.57444495
94MAP3K50.57054661
95MAPK120.56716995
96PDPK10.55534271
97MARK30.52442019
98WNK40.52400529
99ADRBK20.52216711
100DAPK20.52015153
101LATS10.51912745
102PRKCZ0.50741502
103STK100.49727792
104ICK0.49077662
105PIM10.46145753
106CHUK0.45473006
107PBK0.45192357
108RPS6KA40.44947714
109SYK0.44677217
110GSK3A0.44462162
111STK38L0.44450114
112GRK50.44343906
113STK40.44210787
114PIM20.44114706
115TLK10.43760015
116IGF1R0.43656880
117PDK10.42799711
118PRKCQ0.41728610
119CAMK1D0.41222075
120PDK20.39364347
121ITK0.38854619
122MAP2K20.37312483
123EIF2AK20.35755018
124ZAK0.35412211
125MATK0.35152878
126TXK0.34443368
127PRKG20.32229770
128EPHB10.32126730
129PRKAA10.32038021
130SRPK10.32021417
131EGFR0.30677992
132SGK30.29773288
133MAP3K130.29747277
134MET0.29541630
135FGFR30.28572751
136LRRK20.28493427
137BRAF0.28271829
138LCK0.28146557
139ABL10.27494647
140STK30.27307232
141MAP3K80.27186532
142PRKCD0.25710211
143MAPKAPK20.25309908

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary bile acid biosynthesis_Homo sapiens_hsa001204.34760270
2Ascorbate and aldarate metabolism_Homo sapiens_hsa000533.46065701
3Nitrogen metabolism_Homo sapiens_hsa009103.09654461
4Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004003.07022428
5Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010402.80923431
6Arginine biosynthesis_Homo sapiens_hsa002202.80831443
7Tryptophan metabolism_Homo sapiens_hsa003802.68951049
8Complement and coagulation cascades_Homo sapiens_hsa046102.58504621
9Fatty acid degradation_Homo sapiens_hsa000712.56601413
10Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006302.52861619
11Glycine, serine and threonine metabolism_Homo sapiens_hsa002602.46368077
12Pentose and glucuronate interconversions_Homo sapiens_hsa000402.46126413
13Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.39381531
14Peroxisome_Homo sapiens_hsa041462.16628613
15Drug metabolism - cytochrome P450_Homo sapiens_hsa009822.12357854
16Butanoate metabolism_Homo sapiens_hsa006502.05411617
17Histidine metabolism_Homo sapiens_hsa003401.97394605
18Chemical carcinogenesis_Homo sapiens_hsa052041.96116517
19Propanoate metabolism_Homo sapiens_hsa006401.94356232
20Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.94234617
21Fatty acid metabolism_Homo sapiens_hsa012121.89482576
22Drug metabolism - other enzymes_Homo sapiens_hsa009831.88103871
23Staphylococcus aureus infection_Homo sapiens_hsa051501.87709351
24Steroid hormone biosynthesis_Homo sapiens_hsa001401.85882975
25PPAR signaling pathway_Homo sapiens_hsa033201.83873062
26beta-Alanine metabolism_Homo sapiens_hsa004101.83194681
27Caffeine metabolism_Homo sapiens_hsa002321.74456152
28Retinol metabolism_Homo sapiens_hsa008301.71915101
29Selenocompound metabolism_Homo sapiens_hsa004501.68337387
30Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.66957307
31Folate biosynthesis_Homo sapiens_hsa007901.59925651
32Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.54488936
33Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.53304331
34Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.52076111
35Fatty acid elongation_Homo sapiens_hsa000621.49053871
36Phenylalanine metabolism_Homo sapiens_hsa003601.48619188
372-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.40954006
38Pyruvate metabolism_Homo sapiens_hsa006201.36979792
39Tyrosine metabolism_Homo sapiens_hsa003501.33914858
40Cysteine and methionine metabolism_Homo sapiens_hsa002701.32104240
41Bile secretion_Homo sapiens_hsa049761.31981001
42Starch and sucrose metabolism_Homo sapiens_hsa005001.29708253
43Steroid biosynthesis_Homo sapiens_hsa001001.29428577
44Sulfur relay system_Homo sapiens_hsa041221.25630083
45ABC transporters_Homo sapiens_hsa020101.21510366
46Sulfur metabolism_Homo sapiens_hsa009201.20339719
47Biosynthesis of amino acids_Homo sapiens_hsa012301.17643583
48Carbon metabolism_Homo sapiens_hsa012001.16192043
49Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.15017796
50Cyanoamino acid metabolism_Homo sapiens_hsa004601.11818340
51Fat digestion and absorption_Homo sapiens_hsa049751.11178791
52Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.07635532
53One carbon pool by folate_Homo sapiens_hsa006701.06656832
54Lysosome_Homo sapiens_hsa041421.05425789
55Arginine and proline metabolism_Homo sapiens_hsa003300.99184734
56Osteoclast differentiation_Homo sapiens_hsa043800.98584150
57Leishmaniasis_Homo sapiens_hsa051400.97135431
58Maturity onset diabetes of the young_Homo sapiens_hsa049500.96701904
59Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.93717533
60Vitamin digestion and absorption_Homo sapiens_hsa049770.91237525
61Platelet activation_Homo sapiens_hsa046110.88350376
62Lysine degradation_Homo sapiens_hsa003100.84961501
63Vitamin B6 metabolism_Homo sapiens_hsa007500.80907948
64NOD-like receptor signaling pathway_Homo sapiens_hsa046210.78555416
65Pentose phosphate pathway_Homo sapiens_hsa000300.76817741
66Glutathione metabolism_Homo sapiens_hsa004800.76358846
67Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.74197176
68SNARE interactions in vesicular transport_Homo sapiens_hsa041300.72320098
69Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.67510747
70Tuberculosis_Homo sapiens_hsa051520.66104553
71Hematopoietic cell lineage_Homo sapiens_hsa046400.65681472
72Glycerolipid metabolism_Homo sapiens_hsa005610.64175128
73Toll-like receptor signaling pathway_Homo sapiens_hsa046200.58509379
74Acute myeloid leukemia_Homo sapiens_hsa052210.57299060
75Phagosome_Homo sapiens_hsa041450.57146125
76Fatty acid biosynthesis_Homo sapiens_hsa000610.55144316
77Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.53358027
78Metabolic pathways_Homo sapiens_hsa011000.51489793
79NF-kappa B signaling pathway_Homo sapiens_hsa040640.51004918
80B cell receptor signaling pathway_Homo sapiens_hsa046620.50498646
81Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.47626619
82Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.47511319
83Measles_Homo sapiens_hsa051620.46784867
84Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.46776861
85Base excision repair_Homo sapiens_hsa034100.41713112
86Jak-STAT signaling pathway_Homo sapiens_hsa046300.40321752
87Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.40186850
88Galactose metabolism_Homo sapiens_hsa000520.35354123
89Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.33330404
90Influenza A_Homo sapiens_hsa051640.30961207
91Transcriptional misregulation in cancer_Homo sapiens_hsa052020.30205291
92Fructose and mannose metabolism_Homo sapiens_hsa000510.29528147
93Leukocyte transendothelial migration_Homo sapiens_hsa046700.29326061
94alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.28008729
95Linoleic acid metabolism_Homo sapiens_hsa005910.21653071
96Adipocytokine signaling pathway_Homo sapiens_hsa049200.18762668
97Insulin resistance_Homo sapiens_hsa049310.17943358
98Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.11519895
99Prion diseases_Homo sapiens_hsa050200.06901491
100Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.05577517
101Glycerophospholipid metabolism_Homo sapiens_hsa005640.05208002
102Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.03118680
103Glycosaminoglycan degradation_Homo sapiens_hsa005310.02598453
104Pyrimidine metabolism_Homo sapiens_hsa002400.02500544
105Malaria_Homo sapiens_hsa05144-0.1962862
106Insulin signaling pathway_Homo sapiens_hsa04910-0.1945960
107Regulation of autophagy_Homo sapiens_hsa04140-0.1940845
108Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014-0.1874339
109Ovarian steroidogenesis_Homo sapiens_hsa04913-0.1845031
110Intestinal immune network for IgA production_Homo sapiens_hsa04672-0.1733336
111Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604-0.1721510
112Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623-0.1563283
113Hepatitis C_Homo sapiens_hsa05160-0.1352946
114Systemic lupus erythematosus_Homo sapiens_hsa05322-0.1243267
115African trypanosomiasis_Homo sapiens_hsa05143-0.1143952
116Renin-angiotensin system_Homo sapiens_hsa04614-0.1113029
117Pertussis_Homo sapiens_hsa05133-0.1030975
118Other glycan degradation_Homo sapiens_hsa00511-0.0914475
119AMPK signaling pathway_Homo sapiens_hsa04152-0.0587269
120Legionellosis_Homo sapiens_hsa05134-0.0468264
121Arachidonic acid metabolism_Homo sapiens_hsa00590-0.0408663
122RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622-0.0323992
123Glucagon signaling pathway_Homo sapiens_hsa04922-0.0253789

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