Rank | Gene Set | Z-score |
---|---|---|
1 | protein neddylation (GO:0045116) | 5.59420922 |
2 | central nervous system myelination (GO:0022010) | 4.66703988 |
3 | axon ensheathment in central nervous system (GO:0032291) | 4.66703988 |
4 | neutrophil activation involved in immune response (GO:0002283) | 4.66244379 |
5 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.46792872 |
6 | CENP-A containing nucleosome assembly (GO:0034080) | 4.33087096 |
7 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.32980424 |
8 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.27396727 |
9 | ATP synthesis coupled proton transport (GO:0015986) | 4.27396727 |
10 | rRNA modification (GO:0000154) | 4.24982914 |
11 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 4.17973851 |
12 | chromatin remodeling at centromere (GO:0031055) | 4.11350606 |
13 | rRNA methylation (GO:0031167) | 4.05937716 |
14 | long-chain fatty acid biosynthetic process (GO:0042759) | 3.97912763 |
15 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.87713688 |
16 | ribosome assembly (GO:0042255) | 3.82135524 |
17 | fatty acid elongation (GO:0030497) | 3.79608159 |
18 | purine nucleobase biosynthetic process (GO:0009113) | 3.72117391 |
19 | establishment of integrated proviral latency (GO:0075713) | 3.66759228 |
20 | DNA double-strand break processing (GO:0000729) | 3.66320126 |
21 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.63069238 |
22 | respiratory electron transport chain (GO:0022904) | 3.62514946 |
23 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 3.58633999 |
24 | histone exchange (GO:0043486) | 3.57144139 |
25 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.55471518 |
26 | positive regulation of monocyte chemotaxis (GO:0090026) | 3.53719974 |
27 | electron transport chain (GO:0022900) | 3.52746259 |
28 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.49151724 |
29 | NADH dehydrogenase complex assembly (GO:0010257) | 3.49151724 |
30 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.49151724 |
31 | positive regulation of ligase activity (GO:0051351) | 3.48227357 |
32 | mitotic metaphase plate congression (GO:0007080) | 3.42748019 |
33 | DNA catabolic process, exonucleolytic (GO:0000738) | 3.39850454 |
34 | DNA deamination (GO:0045006) | 3.38523709 |
35 | protein complex biogenesis (GO:0070271) | 3.37685457 |
36 | regulation of metalloenzyme activity (GO:0048552) | 3.34547745 |
37 | regulation of ubiquitin-protein transferase activity (GO:0051438) | 3.24304502 |
38 | histone mRNA metabolic process (GO:0008334) | 3.22215636 |
39 | maturation of 5.8S rRNA (GO:0000460) | 3.21670183 |
40 | chaperone-mediated protein transport (GO:0072321) | 3.21310987 |
41 | metaphase plate congression (GO:0051310) | 3.20422553 |
42 | DNA replication checkpoint (GO:0000076) | 3.19021250 |
43 | regulation of ligase activity (GO:0051340) | 3.17058175 |
44 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 3.16062962 |
45 | isotype switching (GO:0045190) | 3.16062962 |
46 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 3.16062962 |
47 | DNA replication-independent nucleosome assembly (GO:0006336) | 3.15736330 |
48 | DNA replication-independent nucleosome organization (GO:0034724) | 3.15736330 |
49 | nucleobase biosynthetic process (GO:0046112) | 3.15363099 |
50 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 3.07083988 |
51 | proteasome assembly (GO:0043248) | 3.06179660 |
52 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 3.04946531 |
53 | regulation of mitotic spindle checkpoint (GO:1903504) | 3.04946531 |
54 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 3.04629598 |
55 | pseudouridine synthesis (GO:0001522) | 3.02441597 |
56 | phagosome maturation (GO:0090382) | 3.02126225 |
57 | protein K6-linked ubiquitination (GO:0085020) | 3.01918020 |
58 | signal peptide processing (GO:0006465) | 3.00785659 |
59 | telomere maintenance via semi-conservative replication (GO:0032201) | 3.00236018 |
60 | regulation of activation of Janus kinase activity (GO:0010533) | 2.98963775 |
61 | purine-containing compound salvage (GO:0043101) | 2.98474049 |
62 | neutrophil activation (GO:0042119) | 2.96521632 |
63 | lactate metabolic process (GO:0006089) | 2.95880335 |
64 | G1/S transition of mitotic cell cycle (GO:0000082) | 2.90023797 |
65 | cell cycle G1/S phase transition (GO:0044843) | 2.90023797 |
66 | IMP biosynthetic process (GO:0006188) | 2.89839739 |
67 | mitotic G2/M transition checkpoint (GO:0044818) | 2.89354064 |
68 | regulation of centriole replication (GO:0046599) | 2.89240148 |
69 | regulation of memory T cell differentiation (GO:0043380) | 2.88772037 |
70 | mannosylation (GO:0097502) | 2.88734882 |
71 | DNA strand elongation involved in DNA replication (GO:0006271) | 2.86479771 |
72 | mitochondrial respiratory chain complex assembly (GO:0033108) | 2.86315828 |
73 | GPI anchor biosynthetic process (GO:0006506) | 2.86257402 |
74 | negative regulation of protein ubiquitination (GO:0031397) | 2.84458313 |
75 | platelet dense granule organization (GO:0060155) | 2.83898980 |
76 | protein targeting to mitochondrion (GO:0006626) | 2.83759275 |
77 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.83185302 |
78 | termination of RNA polymerase III transcription (GO:0006386) | 2.83185302 |
79 | regulation of cellular amine metabolic process (GO:0033238) | 2.81989230 |
80 | DNA damage response, signal transduction by p53 class mediator (GO:0030330) | 2.81373126 |
81 | respiratory burst (GO:0045730) | 2.80968677 |
82 | DNA ligation (GO:0006266) | 2.80720346 |
83 | pyrimidine deoxyribonucleotide metabolic process (GO:0009219) | 2.80287194 |
84 | protein K11-linked ubiquitination (GO:0070979) | 2.79061545 |
85 | granulocyte activation (GO:0036230) | 2.77946925 |
86 | isoprenoid biosynthetic process (GO:0008299) | 2.77158543 |
87 | preassembly of GPI anchor in ER membrane (GO:0016254) | 2.75422633 |
88 | kinetochore organization (GO:0051383) | 2.74660847 |
89 | positive regulation of interleukin-17 production (GO:0032740) | 2.74582553 |
90 | regulation of cellular amino acid metabolic process (GO:0006521) | 2.74533652 |
91 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 2.74135883 |
92 | establishment of chromosome localization (GO:0051303) | 2.71489790 |
93 | cholesterol biosynthetic process (GO:0006695) | 2.71256664 |
94 | protein localization to mitochondrion (GO:0070585) | 2.71174524 |
95 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 2.70831402 |
96 | cullin deneddylation (GO:0010388) | 2.70720989 |
97 | DNA strand elongation (GO:0022616) | 2.70687608 |
98 | RNA capping (GO:0036260) | 2.70549993 |
99 | 7-methylguanosine RNA capping (GO:0009452) | 2.70549993 |
100 | telomere maintenance via recombination (GO:0000722) | 2.70227367 |
101 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 2.70170055 |
102 | negative regulation of neurotransmitter transport (GO:0051589) | 2.68861584 |
103 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.68485424 |
104 | mitotic G2 DNA damage checkpoint (GO:0007095) | 2.67294141 |
105 | positive regulation of cell cycle arrest (GO:0071158) | 2.67011504 |
106 | protein localization to kinetochore (GO:0034501) | 2.66815406 |
107 | 7-methylguanosine mRNA capping (GO:0006370) | 2.66812402 |
108 | positive regulation of transcription elongation from RNA polymerase II promoter (GO:0032968) | 2.66648262 |
109 | transcription elongation from RNA polymerase I promoter (GO:0006362) | 2.66299360 |
110 | eosinophil chemotaxis (GO:0048245) | 2.65026890 |
111 | negative regulation of neurotransmitter secretion (GO:0046929) | 2.64482252 |
112 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 2.63745652 |
113 | regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645) | 2.61767216 |
114 | ribosomal small subunit biogenesis (GO:0042274) | 2.60161032 |
115 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.59469444 |
116 | positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725) | 2.57724258 |
117 | leukocyte degranulation (GO:0043299) | 2.55435532 |
118 | antigen processing and presentation of peptide antigen via MHC class I (GO:0002474) | 2.55019099 |
119 | substantia nigra development (GO:0021762) | 2.54601737 |
120 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 2.54114134 |
121 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.51902096 |
122 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 2.51902096 |
123 | negative regulation of ligase activity (GO:0051352) | 2.49662736 |
124 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 2.49662736 |
125 | autophagic vacuole fusion (GO:0000046) | 2.49210914 |
126 | energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988) | 2.48155536 |
127 | ATP hydrolysis coupled proton transport (GO:0015991) | 2.48155536 |
128 | superoxide anion generation (GO:0042554) | 2.47526254 |
129 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.47427770 |
130 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.47427770 |
131 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 2.47427770 |
132 | GPI anchor metabolic process (GO:0006505) | 2.45999706 |
133 | hydrogen ion transmembrane transport (GO:1902600) | 2.45212196 |
134 | sterol biosynthetic process (GO:0016126) | 2.45037503 |
135 | cellular response to interferon-beta (GO:0035458) | 2.44666983 |
136 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 2.43704227 |
137 | cytochrome complex assembly (GO:0017004) | 2.42814684 |
138 | regulation of interleukin-17 production (GO:0032660) | 2.42381331 |
139 | establishment of viral latency (GO:0019043) | 2.42194252 |
140 | mast cell activation (GO:0045576) | 2.42166964 |
141 | respiratory chain complex IV assembly (GO:0008535) | 2.41699312 |
142 | proton transport (GO:0015992) | 2.41174451 |
143 | amyloid precursor protein metabolic process (GO:0042982) | 2.39783737 |
144 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.38718078 |
145 | GTP biosynthetic process (GO:0006183) | 2.38121741 |
146 | positive regulation of T-helper 1 type immune response (GO:0002827) | 2.37135011 |
147 | regulation of monocyte chemotaxis (GO:0090025) | 2.36300843 |
148 | eosinophil migration (GO:0072677) | 2.35368870 |
149 | protein deneddylation (GO:0000338) | 2.35335615 |
150 | intracellular pH reduction (GO:0051452) | 2.34420873 |
151 | Rap protein signal transduction (GO:0032486) | 2.33961894 |
152 | hydrogen transport (GO:0006818) | 2.32904796 |
153 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 2.32182258 |
154 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 2.32182258 |
155 | regulation of nitric-oxide synthase biosynthetic process (GO:0051769) | 2.32173012 |
156 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 2.30033415 |
157 | response to redox state (GO:0051775) | 2.28038158 |
158 | presynaptic membrane assembly (GO:0097105) | 2.27959595 |
159 | sequestering of actin monomers (GO:0042989) | 2.27436088 |
160 | transferrin transport (GO:0033572) | 2.27173308 |
161 | regulation of T cell migration (GO:2000404) | 2.26390799 |
162 | cotranslational protein targeting to membrane (GO:0006613) | 2.24495513 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 4.32006063 |
2 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 4.08434163 |
3 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.51610121 |
4 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 3.50748615 |
5 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 3.46210388 |
6 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.37778856 |
7 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 3.23012891 |
8 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 3.09970960 |
9 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 2.91538034 |
10 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.90034474 |
11 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.81959599 |
12 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.67609305 |
13 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.51297136 |
14 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 2.42712582 |
15 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.42472330 |
16 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.38158994 |
17 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.36592736 |
18 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.32700670 |
19 | VDR_22108803_ChIP-Seq_LS180_Human | 2.30294644 |
20 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 2.25316074 |
21 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.25041246 |
22 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.20977681 |
23 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.20684993 |
24 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.18350337 |
25 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 2.17456307 |
26 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.13942608 |
27 | * PADI4_21655091_ChIP-ChIP_MCF-7_Human | 2.10544703 |
28 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 2.03389367 |
29 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.03105394 |
30 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.99915217 |
31 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.98055262 |
32 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.95241150 |
33 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.92619984 |
34 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.92554161 |
35 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.88601780 |
36 | FUS_26573619_Chip-Seq_HEK293_Human | 1.81951756 |
37 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.81384557 |
38 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.81048112 |
39 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.76804215 |
40 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.74544285 |
41 | * PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.73567927 |
42 | * SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.68229972 |
43 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.66174309 |
44 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.66055361 |
45 | * E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.61266838 |
46 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.61043074 |
47 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.60937954 |
48 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.59948243 |
49 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 1.58229616 |
50 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.58178389 |
51 | P300_19829295_ChIP-Seq_ESCs_Human | 1.55712550 |
52 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.54878434 |
53 | * ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.53497322 |
54 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.52151522 |
55 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.51167176 |
56 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.47590739 |
57 | EWS_26573619_Chip-Seq_HEK293_Human | 1.47208769 |
58 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.44935604 |
59 | * KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.43377175 |
60 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.42542792 |
61 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.40266494 |
62 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.40047059 |
63 | * THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.39696284 |
64 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.36427105 |
65 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.35588633 |
66 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 1.35239667 |
67 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.34401781 |
68 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.34355262 |
69 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.34040372 |
70 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.34025113 |
71 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.31000582 |
72 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.30985754 |
73 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.28696553 |
74 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.28696536 |
75 | GATA1_22025678_ChIP-Seq_K562_Human | 1.27944722 |
76 | * SUZ12_18555785_Chip-Seq_ESCs_Mouse | 1.27806419 |
77 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.27637118 |
78 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 1.27477142 |
79 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 1.26785469 |
80 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.26765205 |
81 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.26729983 |
82 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.26243684 |
83 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 1.25051438 |
84 | * BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.24585625 |
85 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.24373813 |
86 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 1.23196184 |
87 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.23003000 |
88 | EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse | 1.20514142 |
89 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.19982038 |
90 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 1.19687271 |
91 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.18793936 |
92 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 1.17400378 |
93 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 1.17400378 |
94 | P300_18555785_Chip-Seq_ESCs_Mouse | 1.16966998 |
95 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 1.16675264 |
96 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.15968377 |
97 | * CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 1.14420987 |
98 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.13612508 |
99 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.13056715 |
100 | * FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 1.12539053 |
101 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.12433014 |
102 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.11659553 |
103 | NMYC_18555785_Chip-Seq_ESCs_Mouse | 1.11531852 |
104 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.11378492 |
105 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.10946374 |
106 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.09602744 |
107 | RUNX1_27457419_Chip-Seq_LIVER_Mouse | 1.09037912 |
108 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.08538860 |
109 | TAL1_26923725_Chip-Seq_HPCs_Mouse | 1.08235222 |
110 | SALL4_22934838_ChIP-ChIP_CD34+_Human | 1.08135586 |
111 | SOX2_18555785_Chip-Seq_ESCs_Mouse | 1.07873083 |
112 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 1.07782245 |
113 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.06370951 |
114 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.06024300 |
115 | JUN_21703547_ChIP-Seq_K562_Human | 1.05597326 |
116 | SMAD1_18555785_Chip-Seq_ESCs_Mouse | 1.05477260 |
117 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.04506806 |
118 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.03941141 |
119 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.03676704 |
120 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.03023819 |
121 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.02933022 |
122 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.01548800 |
123 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.99961784 |
124 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 0.99878680 |
125 | TFEB_21752829_ChIP-Seq_HELA_Human | 0.99847341 |
126 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 0.99158206 |
127 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.96986719 |
128 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.96253082 |
129 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.96253082 |
130 | * SPI1_23547873_ChIP-Seq_NB4_Human | 0.96231102 |
131 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 0.95056972 |
132 | KLF4_18555785_Chip-Seq_ESCs_Mouse | 0.93672425 |
133 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 0.93383794 |
134 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.92783447 |
135 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.92584033 |
136 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.92402500 |
137 | OCT4_18555785_Chip-Seq_ESCs_Mouse | 0.92286689 |
138 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.91297526 |
139 | ELF5_23300383_ChIP-Seq_T47D_Human | 0.91277088 |
140 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 0.91268076 |
141 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.90557845 |
142 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 0.89158436 |
143 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.86369629 |
144 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 0.85763237 |
145 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.84721997 |
146 | XRN2_22483619_ChIP-Seq_HELA_Human | 0.83343548 |
147 | KDM5A_27292631_Chip-Seq_BREAST_Human | 0.82165782 |
148 | ZNF274_21170338_ChIP-Seq_K562_Hela | 0.80258388 |
149 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 0.79559483 |
150 | * ZFX_18555785_ChIP-Seq_MESCs_Mouse | 0.79012542 |
151 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.78800642 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0004957_abnormal_blastocyst_morpholog | 3.81091202 |
2 | MP0008058_abnormal_DNA_repair | 3.65598873 |
3 | MP0010094_abnormal_chromosome_stability | 3.52467912 |
4 | MP0003880_abnormal_central_pattern | 3.33565163 |
5 | MP0003806_abnormal_nucleotide_metabolis | 3.31863392 |
6 | MP0003693_abnormal_embryo_hatching | 3.21974092 |
7 | MP0002148_abnormal_hypersensitivity_rea | 3.06234814 |
8 | MP0009785_altered_susceptibility_to | 2.99385310 |
9 | MP0005464_abnormal_platelet_physiology | 2.97773518 |
10 | MP0001835_abnormal_antigen_presentation | 2.88379073 |
11 | MP0001529_abnormal_vocalization | 2.69809024 |
12 | MP0005671_abnormal_response_to | 2.62841015 |
13 | MP0000920_abnormal_myelination | 2.59799309 |
14 | MP0008877_abnormal_DNA_methylation | 2.59355378 |
15 | MP0003950_abnormal_plasma_membrane | 2.53674582 |
16 | MP0001986_abnormal_taste_sensitivity | 2.49879615 |
17 | MP0003111_abnormal_nucleus_morphology | 2.49257459 |
18 | MP0003077_abnormal_cell_cycle | 2.42218983 |
19 | MP0006036_abnormal_mitochondrial_physio | 2.40663238 |
20 | MP0003724_increased_susceptibility_to | 2.37566331 |
21 | MP0005000_abnormal_immune_tolerance | 2.32904154 |
22 | MP0001905_abnormal_dopamine_level | 2.32723181 |
23 | MP0005171_absent_coat_pigmentation | 2.26458864 |
24 | MP0008932_abnormal_embryonic_tissue | 2.26298307 |
25 | MP0006082_CNS_inflammation | 2.18510167 |
26 | MP0001790_abnormal_immune_system | 2.14285046 |
27 | MP0005387_immune_system_phenotype | 2.14285046 |
28 | MP0002163_abnormal_gland_morphology | 2.10937529 |
29 | MP0003786_premature_aging | 2.07870515 |
30 | MP0003941_abnormal_skin_development | 2.05910221 |
31 | MP0006035_abnormal_mitochondrial_morpho | 2.01930639 |
32 | MP0003136_yellow_coat_color | 2.00310238 |
33 | MP0005025_abnormal_response_to | 1.98581275 |
34 | MP0008007_abnormal_cellular_replicative | 1.96205933 |
35 | MP0005084_abnormal_gallbladder_morpholo | 1.94957193 |
36 | MP0002419_abnormal_innate_immunity | 1.89643295 |
37 | MP0009379_abnormal_foot_pigmentation | 1.87026640 |
38 | MP0000372_irregular_coat_pigmentation | 1.86223128 |
39 | MP0002723_abnormal_immune_serum | 1.83924060 |
40 | MP0006054_spinal_hemorrhage | 1.75033408 |
41 | MP0002452_abnormal_antigen_presenting | 1.73077761 |
42 | MP0001800_abnormal_humoral_immune | 1.71167183 |
43 | MP0002009_preneoplasia | 1.68329928 |
44 | MP0001819_abnormal_immune_cell | 1.65963293 |
45 | MP0002420_abnormal_adaptive_immunity | 1.65837618 |
46 | MP0002277_abnormal_respiratory_mucosa | 1.63662600 |
47 | MP0003436_decreased_susceptibility_to | 1.63405233 |
48 | MP0004381_abnormal_hair_follicle | 1.61459476 |
49 | MP0004742_abnormal_vestibular_system | 1.58369267 |
50 | MP0008004_abnormal_stomach_pH | 1.55409080 |
51 | MP0008057_abnormal_DNA_replication | 1.54248476 |
52 | MP0005310_abnormal_salivary_gland | 1.53137798 |
53 | MP0003890_abnormal_embryonic-extraembry | 1.50297191 |
54 | MP0009333_abnormal_splenocyte_physiolog | 1.48302644 |
55 | MP0005379_endocrine/exocrine_gland_phen | 1.47246750 |
56 | MP0002876_abnormal_thyroid_physiology | 1.46914731 |
57 | MP0001188_hyperpigmentation | 1.46887885 |
58 | MP0005408_hypopigmentation | 1.46729534 |
59 | MP0001853_heart_inflammation | 1.44596018 |
60 | MP0000685_abnormal_immune_system | 1.44129488 |
61 | MP0004142_abnormal_muscle_tone | 1.43527100 |
62 | MP0002102_abnormal_ear_morphology | 1.42616696 |
63 | MP0000358_abnormal_cell_content/ | 1.42227985 |
64 | MP0002736_abnormal_nociception_after | 1.41437729 |
65 | MP0002735_abnormal_chemical_nociception | 1.40328728 |
66 | MP0001542_abnormal_bone_strength | 1.39685540 |
67 | MP0003656_abnormal_erythrocyte_physiolo | 1.38128795 |
68 | MP0010386_abnormal_urinary_bladder | 1.37850958 |
69 | MP0004147_increased_porphyrin_level | 1.37110250 |
70 | MP0008260_abnormal_autophagy | 1.33896950 |
71 | MP0006276_abnormal_autonomic_nervous | 1.31594278 |
72 | MP0001968_abnormal_touch/_nociception | 1.27142052 |
73 | MP0005409_darkened_coat_color | 1.26101190 |
74 | MP0001730_embryonic_growth_arrest | 1.25874738 |
75 | MP0008872_abnormal_physiological_respon | 1.24350621 |
76 | MP0003186_abnormal_redox_activity | 1.24284537 |
77 | MP0003195_calcinosis | 1.23485029 |
78 | MP0010234_abnormal_vibrissa_follicle | 1.23222411 |
79 | MP0001697_abnormal_embryo_size | 1.19225225 |
80 | MP0006072_abnormal_retinal_apoptosis | 1.18077012 |
81 | MP0002272_abnormal_nervous_system | 1.17809716 |
82 | MP0000015_abnormal_ear_pigmentation | 1.16638169 |
83 | MP0002405_respiratory_system_inflammati | 1.16062524 |
84 | MP0009697_abnormal_copulation | 1.15500657 |
85 | MP0003718_maternal_effect | 1.13686726 |
86 | MP0001533_abnormal_skeleton_physiology | 1.13057539 |
87 | MP0002734_abnormal_mechanical_nocicepti | 1.13011112 |
88 | MP0004215_abnormal_myocardial_fiber | 1.12447631 |
89 | MP0010307_abnormal_tumor_latency | 1.11015830 |
90 | MP0010352_gastrointestinal_tract_polyps | 1.10409532 |
91 | MP0000716_abnormal_immune_system | 1.09885853 |
92 | MP0000350_abnormal_cell_proliferation | 1.09518533 |
93 | MP0002006_tumorigenesis | 1.09466643 |
94 | MP0002019_abnormal_tumor_incidence | 1.07653205 |
95 | MP0002064_seizures | 1.05029718 |
96 | MP0000313_abnormal_cell_death | 1.03300440 |
97 | MP0001970_abnormal_pain_threshold | 1.03123652 |
98 | MP0002638_abnormal_pupillary_reflex | 1.01983804 |
99 | MP0001845_abnormal_inflammatory_respons | 1.01590592 |
100 | MP0005636_abnormal_mineral_homeostasis | 1.00540396 |
101 | MP0003763_abnormal_thymus_physiology | 0.99657901 |
102 | MP0005164_abnormal_response_to | 0.99257975 |
103 | MP0001727_abnormal_embryo_implantation | 0.96924344 |
104 | MP0003690_abnormal_glial_cell | 0.96704386 |
105 | MP0004270_analgesia | 0.95711101 |
106 | MP0002933_joint_inflammation | 0.94921075 |
107 | MP0005058_abnormal_lysosome_morphology | 0.94883626 |
108 | MP0002837_dystrophic_cardiac_calcinosis | 0.94281074 |
109 | MP0001440_abnormal_grooming_behavior | 0.93694412 |
110 | MP0009046_muscle_twitch | 0.93582924 |
111 | MP0002398_abnormal_bone_marrow | 0.93474229 |
112 | MP0001919_abnormal_reproductive_system | 0.93273713 |
113 | MP0004782_abnormal_surfactant_physiolog | 0.92534226 |
114 | MP0005451_abnormal_body_composition | 0.92355853 |
115 | MP0001929_abnormal_gametogenesis | 0.92212757 |
116 | MP0005410_abnormal_fertilization | 0.91388209 |
117 | MP0005075_abnormal_melanosome_morpholog | 0.90855444 |
118 | MP0000647_abnormal_sebaceous_gland | 0.89928897 |
119 | MP0002210_abnormal_sex_determination | 0.87970899 |
120 | MP0005501_abnormal_skin_physiology | 0.87881304 |
121 | MP0004510_myositis | 0.87814648 |
122 | MP0008995_early_reproductive_senescence | 0.85344164 |
123 | MP0003866_abnormal_defecation | 0.85146647 |
124 | MP0005083_abnormal_biliary_tract | 0.85068039 |
125 | MP0002396_abnormal_hematopoietic_system | 0.84426675 |
126 | MP0005389_reproductive_system_phenotype | 0.84360257 |
127 | MP0003567_abnormal_fetal_cardiomyocyte | 0.83873831 |
128 | MP0000490_abnormal_crypts_of | 0.83693048 |
129 | MP0010678_abnormal_skin_adnexa | 0.82492201 |
130 | MP0001346_abnormal_lacrimal_gland | 0.82490993 |
131 | MP0008775_abnormal_heart_ventricle | 0.82408727 |
132 | MP0000343_altered_response_to | 0.81987969 |
133 | MP0002722_abnormal_immune_system | 0.81658839 |
134 | MP0000681_abnormal_thyroid_gland | 0.81305321 |
135 | MP0010155_abnormal_intestine_physiology | 0.80849590 |
136 | MP0001486_abnormal_startle_reflex | 0.80844303 |
137 | MP0000465_gastrointestinal_hemorrhage | 0.80621796 |
138 | MP0002429_abnormal_blood_cell | 0.80409860 |
139 | MP0001851_eye_inflammation | 0.80299079 |
140 | MP0002080_prenatal_lethality | 0.79330500 |
141 | MP0008469_abnormal_protein_level | 0.79094667 |
142 | MP0009745_abnormal_behavioral_response | 0.78925233 |
143 | MP0001485_abnormal_pinna_reflex | 0.78284009 |
144 | MP0000653_abnormal_sex_gland | 0.77961841 |
145 | MP0005395_other_phenotype | 0.76767430 |
146 | MP0001881_abnormal_mammary_gland | 0.76469382 |
147 | MP0000604_amyloidosis | 0.75800343 |
148 | MP0004134_abnormal_chest_morphology | 0.75501409 |
149 | MP0001764_abnormal_homeostasis | 0.75454539 |
150 | MP0002166_altered_tumor_susceptibility | 0.75435654 |
151 | MP0003448_altered_tumor_morphology | 0.74541750 |
152 | MP0001963_abnormal_hearing_physiology | 0.74234985 |
153 | MP0000689_abnormal_spleen_morphology | 0.73709160 |
154 | MP0008873_increased_physiological_sensi | 0.73505124 |
155 | MP0008875_abnormal_xenobiotic_pharmacok | 0.72974663 |
156 | MP0001672_abnormal_embryogenesis/_devel | 0.72818605 |
157 | MP0005380_embryogenesis_phenotype | 0.72818605 |
158 | MP0001145_abnormal_male_reproductive | 0.72633175 |
159 | MP0003011_delayed_dark_adaptation | 0.72586028 |
160 | MP0002132_abnormal_respiratory_system | 0.71580446 |
161 | MP0003634_abnormal_glial_cell | 0.71426647 |
162 | MP0003183_abnormal_peptide_metabolism | 0.71353957 |
163 | MP0002938_white_spotting | 0.69926949 |
164 | MP0009763_increased_sensitivity_to | 0.69524159 |
165 | MP0002095_abnormal_skin_pigmentation | 0.69416568 |
166 | MP0001119_abnormal_female_reproductive | 0.69400980 |
167 | MP0002796_impaired_skin_barrier | 0.69227291 |
168 | MP0005174_abnormal_tail_pigmentation | 0.68755440 |
169 | MP0000427_abnormal_hair_cycle | 0.68410839 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Acute necrotizing encephalopathy (HP:0006965) | 5.15403391 |
2 | Parakeratosis (HP:0001036) | 4.75786503 |
3 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 4.43616889 |
4 | Progressive macrocephaly (HP:0004481) | 4.41337263 |
5 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.38220606 |
6 | Mitochondrial inheritance (HP:0001427) | 4.29897780 |
7 | Acute encephalopathy (HP:0006846) | 3.84029036 |
8 | Increased CSF lactate (HP:0002490) | 3.40321937 |
9 | Hepatocellular necrosis (HP:0001404) | 3.34845444 |
10 | Abnormality of glycolysis (HP:0004366) | 3.28735961 |
11 | Increased serum pyruvate (HP:0003542) | 3.28735961 |
12 | Recurrent abscess formation (HP:0002722) | 3.28665883 |
13 | Increased hepatocellular lipid droplets (HP:0006565) | 3.27482805 |
14 | Renal Fanconi syndrome (HP:0001994) | 3.24477371 |
15 | Congenital ichthyosiform erythroderma (HP:0007431) | 3.19732029 |
16 | 3-Methylglutaconic aciduria (HP:0003535) | 3.17750599 |
17 | Abnormality of methionine metabolism (HP:0010901) | 3.17224623 |
18 | Leukodystrophy (HP:0002415) | 3.12949979 |
19 | Irregular epiphyses (HP:0010582) | 3.01985664 |
20 | Aplastic anemia (HP:0001915) | 2.94322473 |
21 | Recurrent bacterial skin infections (HP:0005406) | 2.90186806 |
22 | Oral leukoplakia (HP:0002745) | 2.86650250 |
23 | Abnormal hair whorl (HP:0010721) | 2.82734680 |
24 | Increased IgM level (HP:0003496) | 2.80044507 |
25 | Sensory axonal neuropathy (HP:0003390) | 2.76783801 |
26 | Optic disc pallor (HP:0000543) | 2.71834606 |
27 | Hepatic necrosis (HP:0002605) | 2.70293185 |
28 | Lipid accumulation in hepatocytes (HP:0006561) | 2.69462960 |
29 | Prolonged bleeding time (HP:0003010) | 2.67712549 |
30 | Abnormality of chromosome stability (HP:0003220) | 2.66861084 |
31 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.64809074 |
32 | Exertional dyspnea (HP:0002875) | 2.63981365 |
33 | Methylmalonic acidemia (HP:0002912) | 2.62660860 |
34 | Increased mean platelet volume (HP:0011877) | 2.59563427 |
35 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.58874697 |
36 | Hepatosplenomegaly (HP:0001433) | 2.55669916 |
37 | Degeneration of anterior horn cells (HP:0002398) | 2.53215083 |
38 | Abnormality of the anterior horn cell (HP:0006802) | 2.53215083 |
39 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.52260034 |
40 | Hypothermia (HP:0002045) | 2.51094534 |
41 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.49550980 |
42 | Vacuolated lymphocytes (HP:0001922) | 2.48663715 |
43 | Respiratory failure (HP:0002878) | 2.44181135 |
44 | Abnormality of macrophages (HP:0004311) | 2.43941678 |
45 | Cerebral hypomyelination (HP:0006808) | 2.42554440 |
46 | Chromsome breakage (HP:0040012) | 2.42277515 |
47 | Hypoglycemic coma (HP:0001325) | 2.40580205 |
48 | Dyschromatopsia (HP:0007641) | 2.39587207 |
49 | Chronic obstructive pulmonary disease (HP:0006510) | 2.38276170 |
50 | Obstructive lung disease (HP:0006536) | 2.38276170 |
51 | Neuroendocrine neoplasm (HP:0100634) | 2.32147330 |
52 | Stomatitis (HP:0010280) | 2.31674253 |
53 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 2.30956011 |
54 | Abnormality of the preputium (HP:0100587) | 2.29958775 |
55 | Abnormal platelet volume (HP:0011876) | 2.29938543 |
56 | Autoamputation (HP:0001218) | 2.29259315 |
57 | Acanthocytosis (HP:0001927) | 2.25299755 |
58 | Eczematoid dermatitis (HP:0000976) | 2.25102675 |
59 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 2.23413610 |
60 | Patchy hypopigmentation of hair (HP:0011365) | 2.22966517 |
61 | Cerebral edema (HP:0002181) | 2.22260866 |
62 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 2.21909581 |
63 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 2.21909581 |
64 | Methylmalonic aciduria (HP:0012120) | 2.20773936 |
65 | Nausea (HP:0002018) | 2.19894763 |
66 | Abnormality of renal resorption (HP:0011038) | 2.18199735 |
67 | Lethargy (HP:0001254) | 2.17247984 |
68 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.15282674 |
69 | Abnormality of T cell number (HP:0011839) | 2.14901403 |
70 | Exercise intolerance (HP:0003546) | 2.14794649 |
71 | Pancytopenia (HP:0001876) | 2.14461873 |
72 | Abnormality of alanine metabolism (HP:0010916) | 2.13501403 |
73 | Hyperalaninemia (HP:0003348) | 2.13501403 |
74 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.13501403 |
75 | Xerostomia (HP:0000217) | 2.11683525 |
76 | Meckel diverticulum (HP:0002245) | 2.11437971 |
77 | Pancreatic islet-cell hyperplasia (HP:0004510) | 2.11356645 |
78 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.11175325 |
79 | Generalized aminoaciduria (HP:0002909) | 2.10311209 |
80 | Severe combined immunodeficiency (HP:0004430) | 2.09720412 |
81 | Medial flaring of the eyebrow (HP:0010747) | 2.09608556 |
82 | Recurrent skin infections (HP:0001581) | 2.09511958 |
83 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.09426970 |
84 | Poikilocytosis (HP:0004447) | 2.09393686 |
85 | Abnormal protein glycosylation (HP:0012346) | 2.07399023 |
86 | Abnormal glycosylation (HP:0012345) | 2.07399023 |
87 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.07399023 |
88 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.07399023 |
89 | Menorrhagia (HP:0000132) | 2.06377029 |
90 | Abnormality of serum amino acid levels (HP:0003112) | 2.05922272 |
91 | Palpitations (HP:0001962) | 2.05909095 |
92 | Metaphyseal dysplasia (HP:0100255) | 2.05350174 |
93 | Symptomatic seizures (HP:0011145) | 2.04572038 |
94 | Congenital, generalized hypertrichosis (HP:0004540) | 2.02312131 |
95 | Reduced antithrombin III activity (HP:0001976) | 2.02249455 |
96 | White forelock (HP:0002211) | 2.01364866 |
97 | Small epiphyses (HP:0010585) | 1.99244381 |
98 | Hypoglycemic seizures (HP:0002173) | 1.98920522 |
99 | Abnormality of the ileum (HP:0001549) | 1.98580928 |
100 | Respiratory difficulties (HP:0002880) | 1.97355752 |
101 | X-linked dominant inheritance (HP:0001423) | 1.96451984 |
102 | Hyperinsulinemic hypoglycemia (HP:0000825) | 1.96293090 |
103 | Biliary tract neoplasm (HP:0100574) | 1.96045663 |
104 | Short middle phalanx of the 5th finger (HP:0004220) | 1.95189652 |
105 | Myelodysplasia (HP:0002863) | 1.95016093 |
106 | Abnormal spermatogenesis (HP:0008669) | 1.94628455 |
107 | IgG deficiency (HP:0004315) | 1.94393988 |
108 | Recurrent pneumonia (HP:0006532) | 1.94140527 |
109 | Increased serum lactate (HP:0002151) | 1.94081124 |
110 | Retrobulbar optic neuritis (HP:0100654) | 1.93889841 |
111 | Optic neuritis (HP:0100653) | 1.93889841 |
112 | Vasculitis (HP:0002633) | 1.92062124 |
113 | T lymphocytopenia (HP:0005403) | 1.91574371 |
114 | Spastic paraparesis (HP:0002313) | 1.91333847 |
115 | Small intestinal stenosis (HP:0012848) | 1.90780791 |
116 | Duodenal stenosis (HP:0100867) | 1.90780791 |
117 | IgM deficiency (HP:0002850) | 1.90573558 |
118 | Neurofibrillary tangles (HP:0002185) | 1.89537712 |
119 | Abnormal number of erythroid precursors (HP:0012131) | 1.87741781 |
120 | Abnormality of urine glucose concentration (HP:0011016) | 1.87113370 |
121 | Glycosuria (HP:0003076) | 1.87113370 |
122 | Thyroiditis (HP:0100646) | 1.85181426 |
123 | Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003) | 1.85156510 |
124 | Absent epiphyses (HP:0010577) | 1.85156510 |
125 | Autoimmune hemolytic anemia (HP:0001890) | 1.85137489 |
126 | Sparse eyelashes (HP:0000653) | 1.84875821 |
127 | Lactic acidosis (HP:0003128) | 1.82526570 |
128 | Ovarian neoplasm (HP:0100615) | 1.82210937 |
129 | Erythroderma (HP:0001019) | 1.81861741 |
130 | Abnormality of the labia minora (HP:0012880) | 1.81756405 |
131 | Abnormality of vitamin B metabolism (HP:0004340) | 1.81753860 |
132 | Colon cancer (HP:0003003) | 1.81279492 |
133 | Neoplasm of the adrenal gland (HP:0100631) | 1.81122879 |
134 | Delayed epiphyseal ossification (HP:0002663) | 1.81084273 |
135 | Abnormality of incisor morphology (HP:0011063) | 1.80279081 |
136 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 1.80227687 |
137 | Abnormality of eosinophils (HP:0001879) | 1.79906078 |
138 | Thyroid carcinoma (HP:0002890) | 1.79797972 |
139 | Anhidrosis (HP:0000970) | 1.79116919 |
140 | Abnormal lung lobation (HP:0002101) | 1.78157292 |
141 | Megaloblastic anemia (HP:0001889) | 1.77611350 |
142 | Increased muscle lipid content (HP:0009058) | 1.77507959 |
143 | Epiphyseal dysplasia (HP:0002656) | 1.76219014 |
144 | Pheochromocytoma (HP:0002666) | 1.72924862 |
145 | Abnormality of sulfur amino acid metabolism (HP:0004339) | 1.72868267 |
146 | Agnosia (HP:0010524) | 1.72531709 |
147 | Hypomagnesemia (HP:0002917) | 1.71570930 |
148 | Stenosis of the external auditory canal (HP:0000402) | 1.71051238 |
149 | Increased intramyocellular lipid droplets (HP:0012240) | 1.70880279 |
150 | Prolonged neonatal jaundice (HP:0006579) | 1.70644442 |
151 | Barrel-shaped chest (HP:0001552) | 1.70260215 |
152 | Nephrogenic diabetes insipidus (HP:0009806) | 1.69659924 |
153 | Hypoplastic pelvis (HP:0008839) | 1.69095149 |
154 | Amniotic constriction ring (HP:0009775) | 1.66618959 |
155 | Abnormality of placental membranes (HP:0011409) | 1.66618959 |
156 | Hypokinesia (HP:0002375) | 1.66166533 |
157 | Hypergammaglobulinemia (HP:0010702) | 1.65712433 |
158 | Hypertensive crisis (HP:0100735) | 1.65360315 |
159 | Mediastinal lymphadenopathy (HP:0100721) | 1.64839505 |
160 | Combined immunodeficiency (HP:0005387) | 1.64565207 |
161 | Type I transferrin isoform profile (HP:0003642) | 1.64555011 |
162 | Peripheral hypomyelination (HP:0007182) | 1.64464699 |
163 | Congenital primary aphakia (HP:0007707) | 1.63659033 |
164 | Atonic seizures (HP:0010819) | 1.63219167 |
165 | Vaginal atresia (HP:0000148) | 1.62164990 |
166 | Petechiae (HP:0000967) | 1.60524039 |
167 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 1.59902221 |
Rank | Gene Set | Z-score |
---|---|---|
1 | PBK | 3.71582251 |
2 | STK39 | 2.92994924 |
3 | ZAK | 2.81970997 |
4 | BCR | 2.71355962 |
5 | VRK2 | 2.65637210 |
6 | TRIM28 | 2.41382187 |
7 | STK16 | 2.39624352 |
8 | CASK | 2.34782676 |
9 | OXSR1 | 2.31532565 |
10 | MAP3K12 | 2.28391729 |
11 | TXK | 2.28270809 |
12 | BMPR1B | 2.24777541 |
13 | MAP3K14 | 2.13629308 |
14 | NEK1 | 2.07867988 |
15 | CDC7 | 2.04856004 |
16 | BMPR2 | 2.00025506 |
17 | TTK | 1.95551049 |
18 | BUB1 | 1.94119666 |
19 | NUAK1 | 1.88102993 |
20 | ARAF | 1.87778815 |
21 | RIPK4 | 1.72633474 |
22 | TAF1 | 1.63235996 |
23 | VRK1 | 1.61182127 |
24 | EIF2AK1 | 1.58980986 |
25 | IRAK4 | 1.55317470 |
26 | WEE1 | 1.53446013 |
27 | NME1 | 1.48923800 |
28 | PIM2 | 1.48246403 |
29 | NME2 | 1.45247410 |
30 | TNIK | 1.42331817 |
31 | MAPKAPK5 | 1.37213265 |
32 | IRAK3 | 1.35936734 |
33 | STK3 | 1.35828034 |
34 | IKBKB | 1.33382335 |
35 | GRK7 | 1.33232490 |
36 | TEC | 1.30864126 |
37 | * MST4 | 1.30822197 |
38 | FRK | 1.29109248 |
39 | EIF2AK3 | 1.27644918 |
40 | EPHB1 | 1.26661555 |
41 | ADRBK2 | 1.23004014 |
42 | CDK19 | 1.22981412 |
43 | PKN1 | 1.21687913 |
44 | BLK | 1.19650033 |
45 | MAP4K2 | 1.19368500 |
46 | IKBKE | 1.19066271 |
47 | PLK1 | 1.16332150 |
48 | LIMK1 | 1.15875579 |
49 | NEK6 | 1.14531112 |
50 | PLK2 | 1.14506016 |
51 | YES1 | 1.12414682 |
52 | MKNK1 | 1.10769397 |
53 | DYRK3 | 1.06023618 |
54 | TBK1 | 1.05747539 |
55 | TAOK3 | 1.04439280 |
56 | PDK2 | 0.99146021 |
57 | MYLK | 0.97765208 |
58 | TSSK6 | 0.97553981 |
59 | MKNK2 | 0.97457566 |
60 | FGR | 0.96035404 |
61 | IRAK1 | 0.94157807 |
62 | WNK3 | 0.90834663 |
63 | PRPF4B | 0.90807108 |
64 | SCYL2 | 0.89431405 |
65 | STK10 | 0.87584881 |
66 | MUSK | 0.85285754 |
67 | PRKCQ | 0.83567004 |
68 | GRK5 | 0.82061315 |
69 | EIF2AK2 | 0.81884225 |
70 | CLK1 | 0.81510160 |
71 | DYRK2 | 0.81466926 |
72 | NLK | 0.77864606 |
73 | CSNK1G3 | 0.77065605 |
74 | CAMK2B | 0.76198795 |
75 | AURKB | 0.72553052 |
76 | AKT3 | 0.71892382 |
77 | LYN | 0.71602529 |
78 | ATR | 0.71024098 |
79 | RPS6KA5 | 0.70952057 |
80 | PRKCE | 0.70689048 |
81 | WNK4 | 0.70129061 |
82 | SYK | 0.70085680 |
83 | LCK | 0.69867053 |
84 | BRSK2 | 0.66331358 |
85 | ABL2 | 0.65855506 |
86 | MAP2K7 | 0.64495325 |
87 | ITK | 0.64120056 |
88 | ERBB3 | 0.63443158 |
89 | MAP4K1 | 0.61974227 |
90 | IRAK2 | 0.61729647 |
91 | ACVR1B | 0.59543070 |
92 | TRPM7 | 0.59367668 |
93 | ILK | 0.59041340 |
94 | PAK4 | 0.58306532 |
95 | CHEK2 | 0.56443145 |
96 | ROCK2 | 0.55283857 |
97 | CSNK1G1 | 0.53910079 |
98 | MAP3K13 | 0.53390513 |
99 | SRPK1 | 0.52606425 |
100 | DAPK1 | 0.51323026 |
101 | ATM | 0.51227327 |
102 | BMX | 0.51141300 |
103 | PNCK | 0.50407963 |
104 | BRSK1 | 0.50000112 |
105 | PRKCD | 0.49368765 |
106 | PLK3 | 0.48941283 |
107 | STK38L | 0.48059453 |
108 | CCNB1 | 0.47867898 |
109 | CAMK2D | 0.47532951 |
110 | CAMK2A | 0.47482963 |
111 | CSNK1A1L | 0.47463043 |
112 | ALK | 0.47143525 |
113 | CSNK2A2 | 0.46650162 |
114 | PIK3CG | 0.45802706 |
115 | MATK | 0.45595309 |
116 | RAF1 | 0.44832302 |
117 | MAP3K5 | 0.43147026 |
118 | PAK1 | 0.43135121 |
119 | BRAF | 0.42879275 |
120 | FER | 0.42663155 |
121 | GRK1 | 0.42520823 |
122 | TYK2 | 0.42423868 |
123 | TLK1 | 0.41749939 |
124 | KIT | 0.41518612 |
125 | FES | 0.40693876 |
126 | SIK3 | 0.40442004 |
127 | CSNK2A1 | 0.40212582 |
128 | CDK8 | 0.39977565 |
129 | CHEK1 | 0.39656944 |
130 | STK4 | 0.39333043 |
131 | JAK3 | 0.39252019 |
132 | CSK | 0.38856860 |
133 | RPS6KA4 | 0.38732655 |
134 | STK24 | 0.38425775 |
135 | BTK | 0.38185582 |
136 | ERBB4 | 0.38175289 |
137 | CAMK2G | 0.37729843 |
138 | PRKG1 | 0.35614463 |
139 | MAP3K8 | 0.35509903 |
140 | TGFBR1 | 0.35136758 |
141 | PLK4 | 0.35064343 |
142 | AURKA | 0.33341151 |
143 | PASK | 0.32981066 |
144 | PTK2B | 0.31425012 |
145 | FLT3 | 0.30023971 |
146 | MARK3 | 0.29908947 |
147 | DAPK3 | 0.29280141 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 4.06660311 |
2 | Proteasome_Homo sapiens_hsa03050 | 3.76990377 |
3 | Protein export_Homo sapiens_hsa03060 | 3.27053939 |
4 | Parkinsons disease_Homo sapiens_hsa05012 | 3.08709888 |
5 | Ribosome_Homo sapiens_hsa03010 | 2.71285503 |
6 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 2.62562164 |
7 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.54537290 |
8 | Alzheimers disease_Homo sapiens_hsa05010 | 2.45095465 |
9 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 2.33223819 |
10 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 2.32344139 |
11 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 2.27540479 |
12 | Allograft rejection_Homo sapiens_hsa05330 | 2.26343124 |
13 | RNA polymerase_Homo sapiens_hsa03020 | 2.21533194 |
14 | Steroid biosynthesis_Homo sapiens_hsa00100 | 2.18742365 |
15 | Huntingtons disease_Homo sapiens_hsa05016 | 2.11036314 |
16 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.93938911 |
17 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.91236459 |
18 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.80257880 |
19 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.78336465 |
20 | RNA transport_Homo sapiens_hsa03013 | 1.77871357 |
21 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.75278170 |
22 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.71748207 |
23 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.69153563 |
24 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.60534992 |
25 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.59832373 |
26 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 1.59591627 |
27 | Phagosome_Homo sapiens_hsa04145 | 1.52904454 |
28 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.52797349 |
29 | Base excision repair_Homo sapiens_hsa03410 | 1.45433330 |
30 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.41366143 |
31 | Cell cycle_Homo sapiens_hsa04110 | 1.40941184 |
32 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 1.39965770 |
33 | Asthma_Homo sapiens_hsa05310 | 1.37082643 |
34 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.36486840 |
35 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.25992689 |
36 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.25518006 |
37 | Basal transcription factors_Homo sapiens_hsa03022 | 1.24246947 |
38 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 1.22702510 |
39 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.21628287 |
40 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 1.17219278 |
41 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.16700800 |
42 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.08404526 |
43 | Malaria_Homo sapiens_hsa05144 | 1.08179519 |
44 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.05679841 |
45 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.03941751 |
46 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.03614804 |
47 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.00330659 |
48 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.99938645 |
49 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.99607122 |
50 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.99275898 |
51 | Pertussis_Homo sapiens_hsa05133 | 0.99003533 |
52 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.98298233 |
53 | Legionellosis_Homo sapiens_hsa05134 | 0.96389636 |
54 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.94693207 |
55 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.94078702 |
56 | Leishmaniasis_Homo sapiens_hsa05140 | 0.93737824 |
57 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.91824879 |
58 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.88749660 |
59 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.88141895 |
60 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.87334125 |
61 | Measles_Homo sapiens_hsa05162 | 0.85161451 |
62 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.83438265 |
63 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.82740745 |
64 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.80549234 |
65 | Salmonella infection_Homo sapiens_hsa05132 | 0.79991284 |
66 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.78961543 |
67 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.77606407 |
68 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.75436070 |
69 | Tuberculosis_Homo sapiens_hsa05152 | 0.74603179 |
70 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.73840450 |
71 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.73788616 |
72 | Shigellosis_Homo sapiens_hsa05131 | 0.72054276 |
73 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.70126592 |
74 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.67474822 |
75 | Homologous recombination_Homo sapiens_hsa03440 | 0.67472546 |
76 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.67196238 |
77 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.66474029 |
78 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.66014845 |
79 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.64105395 |
80 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.64012995 |
81 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.63271173 |
82 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.62858240 |
83 | Peroxisome_Homo sapiens_hsa04146 | 0.61979321 |
84 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.61561998 |
85 | Purine metabolism_Homo sapiens_hsa00230 | 0.59944940 |
86 | Lysosome_Homo sapiens_hsa04142 | 0.59830823 |
87 | Histidine metabolism_Homo sapiens_hsa00340 | 0.58463597 |
88 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.58179405 |
89 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.56936397 |
90 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.56403137 |
91 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.55796896 |
92 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.52903112 |
93 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.51945292 |
94 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.51769904 |
95 | Spliceosome_Homo sapiens_hsa03040 | 0.50566946 |
96 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.48581922 |
97 | Mineral absorption_Homo sapiens_hsa04978 | 0.46574041 |
98 | Phototransduction_Homo sapiens_hsa04744 | 0.45512784 |
99 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.44675233 |
100 | Carbon metabolism_Homo sapiens_hsa01200 | 0.44576807 |
101 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.43668363 |
102 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.43101813 |
103 | RNA degradation_Homo sapiens_hsa03018 | 0.41814027 |
104 | Platelet activation_Homo sapiens_hsa04611 | 0.41512463 |
105 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.41047058 |
106 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.40919111 |
107 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.40337637 |
108 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.40289045 |
109 | Mismatch repair_Homo sapiens_hsa03430 | 0.40269139 |
110 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.39633083 |
111 | Metabolic pathways_Homo sapiens_hsa01100 | 0.38238572 |
112 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.37495894 |
113 | Nicotine addiction_Homo sapiens_hsa05033 | 0.36358740 |
114 | Taste transduction_Homo sapiens_hsa04742 | 0.35340396 |
115 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.35266374 |
116 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.35043675 |
117 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.34608981 |
118 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.34496718 |
119 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.33220162 |
120 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.32886297 |
121 | Viral myocarditis_Homo sapiens_hsa05416 | 0.32008619 |
122 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.31838176 |
123 | Influenza A_Homo sapiens_hsa05164 | 0.31507185 |
124 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.31181971 |
125 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.30930509 |
126 | Other glycan degradation_Homo sapiens_hsa00511 | 0.30916859 |
127 | Alcoholism_Homo sapiens_hsa05034 | 0.30849666 |
128 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.30420854 |
129 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.30303691 |
130 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.30134642 |
131 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.29965109 |
132 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.29938301 |
133 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.28907298 |
134 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.28103656 |
135 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.27963122 |
136 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.27913605 |
137 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.27849807 |
138 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.26875855 |
139 | Hepatitis C_Homo sapiens_hsa05160 | 0.26692479 |
140 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.26091223 |
141 | DNA replication_Homo sapiens_hsa03030 | 0.24103279 |
142 | Morphine addiction_Homo sapiens_hsa05032 | 0.23061095 |
143 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.21736522 |