PDCD11

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: PDCD11 is a NF-kappa-B (NFKB1; 164011)-binding protein that colocalizes with U3 RNA (MIM 180710) in the nucleolus and is required for rRNA maturation and generation of 18S rRNA (Sweet et al., 2003 [PubMed 14624448]; Sweet et al., 2008 [PubMed 17654514]). NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1nuclear pore complex assembly (GO:0051292)5.80690828
2nuclear pore organization (GO:0006999)5.72968121
3folic acid-containing compound biosynthetic process (GO:0009396)4.79588433
4DNA unwinding involved in DNA replication (GO:0006268)4.71896831
5pre-miRNA processing (GO:0031054)4.55458467
6protein localization to kinetochore (GO:0034501)4.53944516
7regulation of gene silencing by RNA (GO:0060966)4.41260269
8regulation of posttranscriptional gene silencing (GO:0060147)4.41260269
9regulation of gene silencing by miRNA (GO:0060964)4.41260269
10pore complex assembly (GO:0046931)4.34582419
11mitotic nuclear envelope disassembly (GO:0007077)4.26715692
12regulation of translational fidelity (GO:0006450)4.23138893
13IMP biosynthetic process (GO:0006188)4.09578635
14heterochromatin organization (GO:0070828)4.05774151
15membrane disassembly (GO:0030397)3.97509369
16nuclear envelope disassembly (GO:0051081)3.97509369
17establishment of integrated proviral latency (GO:0075713)3.92580120
18DNA duplex unwinding (GO:0032508)3.88194269
19DNA geometric change (GO:0032392)3.86282774
20negative regulation of histone methylation (GO:0031061)3.79061598
21DNA replication-dependent nucleosome organization (GO:0034723)3.74827910
22DNA replication-dependent nucleosome assembly (GO:0006335)3.74827910
23proline biosynthetic process (GO:0006561)3.69593988
24formation of translation preinitiation complex (GO:0001731)3.69557932
25regulation of histone H3-K9 methylation (GO:0051570)3.69361882
26chromatin assembly (GO:0031497)3.68808393
27protein complex localization (GO:0031503)3.68073365
28nucleobase biosynthetic process (GO:0046112)3.66021811
29protein localization to chromosome, centromeric region (GO:0071459)3.65974183
30mitotic sister chromatid segregation (GO:0000070)3.58196996
31DNA replication initiation (GO:0006270)3.57440975
32maturation of SSU-rRNA (GO:0030490)3.56688286
33sister chromatid segregation (GO:0000819)3.52992422
34regulation of RNA export from nucleus (GO:0046831)3.48256307
35spliceosomal tri-snRNP complex assembly (GO:0000244)3.47941026
36IMP metabolic process (GO:0046040)3.47427513
37DNA topological change (GO:0006265)3.44465015
38negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.43537327
39DNA strand elongation involved in DNA replication (GO:0006271)3.38890122
40double-strand break repair via nonhomologous end joining (GO:0006303)3.36544852
41non-recombinational repair (GO:0000726)3.36544852
42telomere maintenance via recombination (GO:0000722)3.36502833
43chromosome condensation (GO:0030261)3.35104090
44cellular protein complex localization (GO:0034629)3.34843031
45mitotic chromosome condensation (GO:0007076)3.31226882
46mitotic sister chromatid cohesion (GO:0007064)3.27917397
47dosage compensation (GO:0007549)3.27764242
48regulation of translational termination (GO:0006449)3.26434378
49ribosome assembly (GO:0042255)3.24403198
50DNA strand elongation (GO:0022616)3.21709644
51mitotic recombination (GO:0006312)3.20845989
52ribosome biogenesis (GO:0042254)3.19842085
53mitotic metaphase plate congression (GO:0007080)3.19385101
54positive regulation of chromosome segregation (GO:0051984)3.18143324
55nuclear envelope organization (GO:0006998)3.16916278
56regulation of spindle organization (GO:0090224)3.11289378
57negative regulation of DNA repair (GO:0045738)3.10720350
58regulation of mitotic spindle organization (GO:0060236)3.10559169
59negative regulation of mRNA processing (GO:0050686)3.08106197
60rRNA transcription (GO:0009303)3.06962235
61regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.06851997
62tRNA aminoacylation for protein translation (GO:0006418)3.05818701
63negative regulation of RNA splicing (GO:0033119)3.05490554
64viral transcription (GO:0019083)3.05027884
65DNA synthesis involved in DNA repair (GO:0000731)3.04593472
66ribosomal large subunit biogenesis (GO:0042273)3.03701464
67histone H2A monoubiquitination (GO:0035518)3.02175720
68translational termination (GO:0006415)3.01890702
69paraxial mesoderm development (GO:0048339)3.01629430
70regulation of sister chromatid cohesion (GO:0007063)3.01620711
71tRNA aminoacylation (GO:0043039)3.00845984
72amino acid activation (GO:0043038)3.00845984
73DNA packaging (GO:0006323)3.00782097
74regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.00730310
75ribonucleoprotein complex biogenesis (GO:0022613)3.00724066
76mRNA stabilization (GO:0048255)2.99284059
77RNA stabilization (GO:0043489)2.99284059
78ribosomal small subunit assembly (GO:0000028)2.99119841
79DNA conformation change (GO:0071103)2.99090810
80protein export from nucleus (GO:0006611)2.98696527
81negative regulation of mRNA metabolic process (GO:1903312)2.96135422
82mRNA transport (GO:0051028)2.95915284
83nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.94875330
84maturation of 5.8S rRNA (GO:0000460)2.93932978
85mitotic G1 DNA damage checkpoint (GO:0031571)2.93487193
86translational initiation (GO:0006413)2.93028170
87nucleosome disassembly (GO:0006337)2.92887309
88protein-DNA complex disassembly (GO:0032986)2.92887309
89viral mRNA export from host cell nucleus (GO:0046784)2.92425199
90chromatin assembly or disassembly (GO:0006333)2.91877156
91establishment of viral latency (GO:0019043)2.90888735
92histone H4-K12 acetylation (GO:0043983)2.90025591
93positive regulation of cell cycle checkpoint (GO:1901978)2.89525316
94regulation of translational elongation (GO:0006448)2.89432464
95somatic hypermutation of immunoglobulin genes (GO:0016446)2.87727338
96somatic diversification of immune receptors via somatic mutation (GO:0002566)2.87727338
97telomere maintenance via semi-conservative replication (GO:0032201)2.87601804
98purine nucleobase biosynthetic process (GO:0009113)2.86972885
99regulation of gene silencing (GO:0060968)2.86693868
100regulation of helicase activity (GO:0051095)2.85230386
101metaphase plate congression (GO:0051310)2.84807155
102tetrahydrofolate metabolic process (GO:0046653)2.83819297
103* rRNA metabolic process (GO:0016072)2.83676346
104regulation of hippo signaling (GO:0035330)2.82793523
105snRNA metabolic process (GO:0016073)2.82736902
106DNA replication checkpoint (GO:0000076)2.82266152
107peptidyl-arginine omega-N-methylation (GO:0035247)2.82062807
108termination of RNA polymerase II transcription (GO:0006369)2.80949579
109histone arginine methylation (GO:0034969)2.79704766
110snRNA processing (GO:0016180)2.78707845
111regulation of centriole replication (GO:0046599)2.77888533
112mitochondrial RNA metabolic process (GO:0000959)2.76386417
113telomere maintenance via telomere lengthening (GO:0010833)2.75989182
114nucleobase-containing small molecule interconversion (GO:0015949)2.73379138
115RNA splicing, via transesterification reactions (GO:0000375)2.72730530
116mRNA splicing, via spliceosome (GO:0000398)2.72657155
117RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)2.72657155
118translational elongation (GO:0006414)2.72342929
119spliceosomal snRNP assembly (GO:0000387)2.71356010
120negative regulation of chromosome segregation (GO:0051985)2.71164115
121establishment of apical/basal cell polarity (GO:0035089)2.70169334
122alternative mRNA splicing, via spliceosome (GO:0000380)2.69850729
123RNA transport (GO:0050658)2.69793418
124establishment of RNA localization (GO:0051236)2.69793418
125nucleic acid transport (GO:0050657)2.69793418
126regulation of chromosome segregation (GO:0051983)2.69784832
127* rRNA processing (GO:0006364)2.69568744
128trophectodermal cell differentiation (GO:0001829)2.69312251
129ribosomal small subunit biogenesis (GO:0042274)2.69174533
130nuclear-transcribed mRNA poly(A) tail shortening (GO:0000289)2.69021808
131protein localization to chromosome (GO:0034502)2.68990626
132positive regulation of SMAD protein import into nucleus (GO:0060391)2.68846979
133regulation of nucleobase-containing compound transport (GO:0032239)2.67986708
134mitotic G1/S transition checkpoint (GO:0044819)2.67831265
135positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.66400564
136positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.66400564
137positive regulation of mitotic sister chromatid separation (GO:1901970)2.66400564

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human8.78541686
2FOXM1_23109430_ChIP-Seq_U2OS_Human4.63234436
3* MYC_18555785_ChIP-Seq_MESCs_Mouse3.88212032
4E2F4_17652178_ChIP-ChIP_JURKAT_Human3.44480159
5MYC_19079543_ChIP-ChIP_MESCs_Mouse3.01926200
6* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.92832053
7EGR1_19374776_ChIP-ChIP_THP-1_Human2.91491777
8FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.87869995
9MYC_22102868_ChIP-Seq_BL_Human2.68428710
10* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.46201379
11* KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.28746678
12* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.09668638
13NELFA_20434984_ChIP-Seq_ESCs_Mouse2.06759519
14SMAD1_18555785_ChIP-Seq_MESCs_Mouse2.04798195
15XRN2_22483619_ChIP-Seq_HELA_Human1.98840188
16E2F1_21310950_ChIP-Seq_MCF-7_Human1.96866384
17NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.92935551
18KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.90557449
19KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.90557449
20KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.90557449
21AR_21909140_ChIP-Seq_LNCAP_Human1.81753027
22POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.80809303
23POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.77826372
24MYCN_18555785_ChIP-Seq_MESCs_Mouse1.74529314
25* MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.74337662
26STAT3_1855785_ChIP-Seq_MESCs_Mouse1.68321440
27NANOG_18555785_ChIP-Seq_MESCs_Mouse1.68088753
28EST1_17652178_ChIP-ChIP_JURKAT_Human1.67941705
29* ETS1_20019798_ChIP-Seq_JURKAT_Human1.67231956
30* KDM5A_27292631_Chip-Seq_BREAST_Human1.60187331
31CIITA_25753668_ChIP-Seq_RAJI_Human1.59090532
32SALL1_21062744_ChIP-ChIP_HESCs_Human1.58602838
33CREB1_15753290_ChIP-ChIP_HEK293T_Human1.56329469
34TP63_19390658_ChIP-ChIP_HaCaT_Human1.55924087
35MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.54217225
36VDR_21846776_ChIP-Seq_THP-1_Human1.50771774
37CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.49697064
38FOXP3_21729870_ChIP-Seq_TREG_Human1.41099855
39VDR_23849224_ChIP-Seq_CD4+_Human1.41051584
40TTF2_22483619_ChIP-Seq_HELA_Human1.40431722
41ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.38953798
42FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.38394658
43ZFX_18555785_ChIP-Seq_MESCs_Mouse1.38053939
44DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.37514698
45E2F1_18555785_ChIP-Seq_MESCs_Mouse1.36638261
46HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.36375938
47YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.35837925
48ESR1_15608294_ChIP-ChIP_MCF-7_Human1.35538797
49KLF4_18555785_ChIP-Seq_MESCs_Mouse1.32700480
50TCF3_18692474_ChIP-Seq_MEFs_Mouse1.31890163
51ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.31448799
52CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.30974547
53* DCP1A_22483619_ChIP-Seq_HELA_Human1.30854399
54TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.30485254
55* JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.29611916
56ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.26947730
57* TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.26107455
58GABP_19822575_ChIP-Seq_HepG2_Human1.26106711
59SOX2_18555785_ChIP-Seq_MESCs_Mouse1.24980125
60YY1_21170310_ChIP-Seq_MESCs_Mouse1.24411793
61* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.24206126
62* ERG_20887958_ChIP-Seq_HPC-7_Mouse1.22548485
63CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.21963804
64ELF1_17652178_ChIP-ChIP_JURKAT_Human1.21529210
65KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.20780436
66TFEB_21752829_ChIP-Seq_HELA_Human1.19395271
67SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.17697612
68NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.17595100
69HOXB4_20404135_ChIP-ChIP_EML_Mouse1.17228552
70CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.16833192
71HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.16541317
72DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.15972044
73THAP11_20581084_ChIP-Seq_MESCs_Mouse1.15896478
74NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.15792552
75NANOG_21062744_ChIP-ChIP_HESCs_Human1.15618101
76SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.14739371
77* GABP_17652178_ChIP-ChIP_JURKAT_Human1.14554073
78KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.14063724
79TCF3_18692474_ChIP-Seq_MESCs_Mouse1.14055740
80STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.13779779
81TCF7_22412390_ChIP-Seq_EML_Mouse1.13635841
82POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.13260962
83NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.12296386
84KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.10648771
85PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.10526214
86PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.10420327
87NOTCH1_21737748_ChIP-Seq_TLL_Human1.10411890
88* PADI4_21655091_ChIP-ChIP_MCF-7_Human1.10325021
89KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.08284212
90SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.08101733
91* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.04873302
92ZNF263_19887448_ChIP-Seq_K562_Human1.04584674
93ELK1_19687146_ChIP-ChIP_HELA_Human1.03340798
94KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.03240600
95SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.01652402
96CHD1_26751641_Chip-Seq_LNCaP_Human1.01056194
97ZFP42_18358816_ChIP-ChIP_MESCs_Mouse0.99900835
98UTX_26944678_Chip-Seq_JUKART_Human0.99453187
99KDM2B_26808549_Chip-Seq_DND41_Human0.99263440
100MYCN_21190229_ChIP-Seq_SHEP-21N_Human0.98042335
101* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.97672466
102HIF1A_21447827_ChIP-Seq_MCF-7_Human0.97476713
103TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.97354129
104ATF3_27146783_Chip-Seq_COLON_Human0.96625438
105ELK3_25401928_ChIP-Seq_HUVEC_Human0.95715043
106E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.95687645
107POU5F1_16518401_ChIP-PET_MESCs_Mouse0.94804455
108KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.94770522
109TP63_17297297_ChIP-ChIP_HaCaT_Human0.94184689
110SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.93867830
111* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.92947976
112GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.91631763
113NCOR1_26117541_ChIP-Seq_K562_Human0.90676012
114SOX17_20123909_ChIP-Seq_XEN_Mouse0.90474985
115MAF_26560356_Chip-Seq_TH1_Human0.89748851
116NANOG_18347094_ChIP-ChIP_MESCs_Mouse0.89085210
117* BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.88941798
118PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.88480163
119SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.85160527
120NKX2-5_21415370_ChIP-Seq_HL-1_Mouse0.83813063
121RBPJ_22232070_ChIP-Seq_NCS_Mouse0.80889357
122CLOCK_20551151_ChIP-Seq_293T_Human0.79398906
123TBX5_21415370_ChIP-Seq_HL-1_Mouse0.79223331
124* SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.78288941

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003111_abnormal_nucleus_morphology3.67425179
2MP0003693_abnormal_embryo_hatching3.59612440
3MP0004957_abnormal_blastocyst_morpholog3.56617974
4MP0008057_abnormal_DNA_replication3.54083456
5MP0010094_abnormal_chromosome_stability3.47955655
6MP0003077_abnormal_cell_cycle3.13181682
7MP0010352_gastrointestinal_tract_polyps3.11752949
8MP0003705_abnormal_hypodermis_morpholog2.79569670
9MP0001730_embryonic_growth_arrest2.49033085
10MP0005076_abnormal_cell_differentiation2.35712108
11MP0010307_abnormal_tumor_latency2.25317495
12MP0000350_abnormal_cell_proliferation2.23855617
13MP0005380_embryogenesis_phenotype2.07316381
14MP0001672_abnormal_embryogenesis/_devel2.07316381
15MP0008007_abnormal_cellular_replicative2.06042019
16MP0008058_abnormal_DNA_repair2.02555813
17MP0004197_abnormal_fetal_growth/weight/2.00712580
18MP0002084_abnormal_developmental_patter2.00276251
19MP0008932_abnormal_embryonic_tissue1.95337432
20MP0003984_embryonic_growth_retardation1.93249046
21MP0002088_abnormal_embryonic_growth/wei1.90653144
22MP0002396_abnormal_hematopoietic_system1.88933678
23MP0002085_abnormal_embryonic_tissue1.86916659
24MP0002086_abnormal_extraembryonic_tissu1.86899782
25MP0010030_abnormal_orbit_morphology1.85843833
26MP0001697_abnormal_embryo_size1.81858704
27MP0009697_abnormal_copulation1.79745865
28MP0008877_abnormal_DNA_methylation1.74329198
29MP0003123_paternal_imprinting1.71526770
30MP0003890_abnormal_embryonic-extraembry1.71415831
31MP0002080_prenatal_lethality1.66058119
32MP0005451_abnormal_body_composition1.51696292
33MP0003786_premature_aging1.48280310
34MP0001661_extended_life_span1.48237034
35MP0003566_abnormal_cell_adhesion1.47118914
36MP0001293_anophthalmia1.42121212
37MP0002009_preneoplasia1.41822014
38MP0009278_abnormal_bone_marrow1.39136091
39MP0001849_ear_inflammation1.38803697
40MP0004808_abnormal_hematopoietic_stem1.38756797
41MP0003567_abnormal_fetal_cardiomyocyte1.38525171
42MP0003315_abnormal_perineum_morphology1.37439125
43MP0009053_abnormal_anal_canal1.35507448
44MP0000537_abnormal_urethra_morphology1.34092560
45MP0000490_abnormal_crypts_of1.34050102
46MP0002796_impaired_skin_barrier1.30641957
47MP0003121_genomic_imprinting1.30331706
48MP0000579_abnormal_nail_morphology1.30302931
49MP0003119_abnormal_digestive_system1.28528488
50MP0004185_abnormal_adipocyte_glucose1.27026344
51MP0005023_abnormal_wound_healing1.26334903
52MP0002877_abnormal_melanocyte_morpholog1.23807717
53MP0000733_abnormal_muscle_development1.19957892
54MP0000313_abnormal_cell_death1.19419352
55MP0003718_maternal_effect1.16984286
56MP0002019_abnormal_tumor_incidence1.16532765
57MP0002697_abnormal_eye_size1.13229504
58MP0001915_intracranial_hemorrhage1.10448574
59MP0000428_abnormal_craniofacial_morphol1.10311060
60MP0000703_abnormal_thymus_morphology1.09248080
61MP0009672_abnormal_birth_weight1.09106439
62MP0000358_abnormal_cell_content/1.09079303
63MP0002092_abnormal_eye_morphology1.08536366
64MP0006035_abnormal_mitochondrial_morpho1.06605055
65MP0003385_abnormal_body_wall1.06576793
66MP0004264_abnormal_extraembryonic_tissu1.06368817
67MP0004133_heterotaxia1.04003494
68MP0002111_abnormal_tail_morphology1.03373671
69MP0003221_abnormal_cardiomyocyte_apopto1.01841329
70MP0003937_abnormal_limbs/digits/tail_de1.01704364
71MP0009703_decreased_birth_body0.99632743
72MP0003763_abnormal_thymus_physiology0.98621595
73MP0002060_abnormal_skin_morphology0.98474243
74MP0003300_gastrointestinal_ulcer0.97133979
75MP0009333_abnormal_splenocyte_physiolog0.93870874
76MP0000432_abnormal_head_morphology0.93418544
77MP0002925_abnormal_cardiovascular_devel0.92369786
78MP0003115_abnormal_respiratory_system0.92222889
79MP0001348_abnormal_lacrimal_gland0.91900104
80MP0010234_abnormal_vibrissa_follicle0.90149041
81MP0000762_abnormal_tongue_morphology0.90108441
82MP0003935_abnormal_craniofacial_develop0.88927050
83MP0003283_abnormal_digestive_organ0.88457146
84MP0005623_abnormal_meninges_morphology0.88234253
85MP0004272_abnormal_basement_membrane0.88220885
86MP0001216_abnormal_epidermal_layer0.85304055
87MP0005397_hematopoietic_system_phenotyp0.84751152
88MP0001545_abnormal_hematopoietic_system0.84751152
89MP0002089_abnormal_postnatal_growth/wei0.82941970
90MP0002398_abnormal_bone_marrow0.82752862
91MP0002722_abnormal_immune_system0.81491025
92MP0003806_abnormal_nucleotide_metabolis0.80085420
93MP0000371_diluted_coat_color0.78623731
94MP0005621_abnormal_cell_physiology0.77525553
95MP0000477_abnormal_intestine_morphology0.76247084
96MP0002210_abnormal_sex_determination0.76187156
97MP0003091_abnormal_cell_migration0.76051215
98MP0000689_abnormal_spleen_morphology0.75266693
99MP0001346_abnormal_lacrimal_gland0.74383864
100MP0002249_abnormal_larynx_morphology0.74339515
101MP0003943_abnormal_hepatobiliary_system0.74034988
102MP0002653_abnormal_ependyma_morphology0.73980125
103MP0008770_decreased_survivor_rate0.73963395
104MP0000627_abnormal_mammary_gland0.73825643
105MP0000467_abnormal_esophagus_morphology0.73618773
106MP0001145_abnormal_male_reproductive0.73218500
107MP0004233_abnormal_muscle_weight0.73195788
108MP0005257_abnormal_intraocular_pressure0.72250277
109MP0008260_abnormal_autophagy0.72093567
110MP0003942_abnormal_urinary_system0.71860261
111MP0000678_abnormal_parathyroid_gland0.71663909
112MP0003941_abnormal_skin_development0.70375563
113MP0006292_abnormal_olfactory_placode0.69967786
114MP0002233_abnormal_nose_morphology0.69569542
115MP0001286_abnormal_eye_development0.69446561
116MP0005384_cellular_phenotype0.69346219
117MP0000566_synostosis0.68780115
118MP0000266_abnormal_heart_morphology0.68230032
119MP0002098_abnormal_vibrissa_morphology0.68205173
120MP0001873_stomach_inflammation0.68043710
121MP0000377_abnormal_hair_follicle0.66423345
122MP0003453_abnormal_keratinocyte_physiol0.65388120
123MP0002932_abnormal_joint_morphology0.65087935
124MP0008995_early_reproductive_senescence0.62115395
125MP0010630_abnormal_cardiac_muscle0.62092245
126MP0003861_abnormal_nervous_system0.61452807
127MP0005666_abnormal_adipose_tissue0.60635510
128MP0003755_abnormal_palate_morphology0.60424843
129MP0002075_abnormal_coat/hair_pigmentati0.58866269
130MP0001784_abnormal_fluid_regulation0.57938273
131MP0002429_abnormal_blood_cell0.57063809
132MP0005501_abnormal_skin_physiology0.56310847

Predicted human phenotypes

RankGene SetZ-score
1Ependymoma (HP:0002888)4.31362874
2Microvesicular hepatic steatosis (HP:0001414)3.39648894
3Progressive muscle weakness (HP:0003323)3.36210847
4Selective tooth agenesis (HP:0001592)3.33668655
5Astrocytoma (HP:0009592)3.30237763
6Abnormality of the astrocytes (HP:0100707)3.30237763
7Multiple enchondromatosis (HP:0005701)3.08736229
8Medulloblastoma (HP:0002885)3.06906608
9Progressive external ophthalmoplegia (HP:0000590)2.92851801
10Deviation of the thumb (HP:0009603)2.83743836
11Proximal placement of thumb (HP:0009623)2.75891930
12Basal cell carcinoma (HP:0002671)2.71673564
13Rhabdomyosarcoma (HP:0002859)2.70621650
14Missing ribs (HP:0000921)2.68964767
15Insomnia (HP:0100785)2.68517161
16Overlapping toe (HP:0001845)2.67595666
17Abnormality of the labia minora (HP:0012880)2.63735419
18Chromsome breakage (HP:0040012)2.60609975
19Glioma (HP:0009733)2.60313340
20Reticulocytopenia (HP:0001896)2.59414622
21Abnormal number of incisors (HP:0011064)2.56488230
22Neoplasm of the oral cavity (HP:0100649)2.50846222
23Neoplasm of striated muscle (HP:0009728)2.50548629
24Chromosomal breakage induced by crosslinking agents (HP:0003221)2.46168186
25Colon cancer (HP:0003003)2.42993372
26Abnormality of the preputium (HP:0100587)2.42580020
27Dysmetric saccades (HP:0000641)2.39401608
28Overriding aorta (HP:0002623)2.38422372
29Ulnar bowing (HP:0003031)2.37808161
30Absent thumb (HP:0009777)2.37124792
31Aplasia/Hypoplasia of the sacrum (HP:0008517)2.37050687
32Rib fusion (HP:0000902)2.37025504
33Absent radius (HP:0003974)2.30324140
34Aplasia/hypoplasia of the humerus (HP:0006507)2.28550486
35Impulsivity (HP:0100710)2.28280554
36Increased nuchal translucency (HP:0010880)2.25781103
37Pseudobulbar signs (HP:0002200)2.25442422
38Volvulus (HP:0002580)2.25379772
39Birth length less than 3rd percentile (HP:0003561)2.24429545
40Short humerus (HP:0005792)2.24243890
41Elfin facies (HP:0004428)2.22782699
42Facial cleft (HP:0002006)2.21614364
43Short 4th metacarpal (HP:0010044)2.17698185
44Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.17698185
45Squamous cell carcinoma (HP:0002860)2.17536544
46Patellar aplasia (HP:0006443)2.16102121
47Nephroblastoma (Wilms tumor) (HP:0002667)2.14599235
48Skin tags (HP:0010609)2.13864580
49Ectopic kidney (HP:0000086)2.13852231
50Absent forearm bone (HP:0003953)2.11630079
51Aplasia involving forearm bones (HP:0009822)2.11630079
52Ankyloglossia (HP:0010296)2.11572343
5311 pairs of ribs (HP:0000878)2.11217739
54Long eyelashes (HP:0000527)2.10657757
55Urethral obstruction (HP:0000796)2.09043743
56Prominent nose (HP:0000448)2.08658835
57Facial hemangioma (HP:0000329)2.07798074
58Increased density of long bones (HP:0006392)2.06002411
59Preauricular skin tag (HP:0000384)2.05862940
60Heterotopia (HP:0002282)2.05089220
61Abnormality of oral frenula (HP:0000190)2.04332797
62Premature ovarian failure (HP:0008209)2.02616646
63Cerebral aneurysm (HP:0004944)2.00186443
64Hyperacusis (HP:0010780)1.99984856
65Supernumerary ribs (HP:0005815)1.99620388
66Myelodysplasia (HP:0002863)1.98892971
67Biliary tract neoplasm (HP:0100574)1.98695438
68Sandal gap (HP:0001852)1.98267773
69Atresia of the external auditory canal (HP:0000413)1.97964582
70Abnormality of cells of the erythroid lineage (HP:0012130)1.97404170
71Abnormality of chromosome stability (HP:0003220)1.97083279
72Ankle contracture (HP:0006466)1.96404820
73Aplasia/Hypoplasia of the patella (HP:0006498)1.95942866
74Embryonal renal neoplasm (HP:0011794)1.95506334
75Glossoptosis (HP:0000162)1.94463752
76Trismus (HP:0000211)1.94388965
77Renovascular hypertension (HP:0100817)1.94290296
78Spinal muscular atrophy (HP:0007269)1.93300248
79Malignant gastrointestinal tract tumors (HP:0006749)1.93231722
80Gastrointestinal carcinoma (HP:0002672)1.93231722
81Agnosia (HP:0010524)1.92962398
82Abnormality of the fingertips (HP:0001211)1.92191519
83Sparse lateral eyebrow (HP:0005338)1.91715975
84Supernumerary bones of the axial skeleton (HP:0009144)1.91672534
85Cafe-au-lait spot (HP:0000957)1.89904496
86Abnormal number of erythroid precursors (HP:0012131)1.89822302
87Amaurosis fugax (HP:0100576)1.89469724
88Choanal atresia (HP:0000453)1.87666119
89Vertebral arch anomaly (HP:0008438)1.87201614
90Horseshoe kidney (HP:0000085)1.86693187
91Anal stenosis (HP:0002025)1.86542210
92Ragged-red muscle fibers (HP:0003200)1.85270642
93Broad thumb (HP:0011304)1.85063646
94Abnormality of the carotid arteries (HP:0005344)1.84562724
95Breast hypoplasia (HP:0003187)1.82923615
96Esophageal atresia (HP:0002032)1.82566623
97Skull defect (HP:0001362)1.82098717
98Progressive hearing impairment (HP:0001730)1.81927994
99High anterior hairline (HP:0009890)1.81854355
100Cortical dysplasia (HP:0002539)1.81358719
101Renal duplication (HP:0000075)1.80525210
102Abnormality of the umbilical cord (HP:0010881)1.80096681
103Back pain (HP:0003418)1.79824752
104High pitched voice (HP:0001620)1.79366870
105Small intestinal stenosis (HP:0012848)1.79104023
106Duodenal stenosis (HP:0100867)1.79104023
107Meckel diverticulum (HP:0002245)1.75827608
108Long palpebral fissure (HP:0000637)1.75764213
109Vertebral fusion (HP:0002948)1.75345011
110Patellar dislocation (HP:0002999)1.75159576
111Abnormality of the calcaneus (HP:0008364)1.75065061
112Degeneration of anterior horn cells (HP:0002398)1.73899321
113Abnormality of the anterior horn cell (HP:0006802)1.73899321
114Hypopigmentation of the fundus (HP:0007894)1.73710114
115Abnormality of the ileum (HP:0001549)1.73438330
116Neoplasm of the pancreas (HP:0002894)1.72514586
117Abnormality of the antihelix (HP:0009738)1.72507831
118Diastasis recti (HP:0001540)1.71907655
119Insidious onset (HP:0003587)1.69609838
120Termporal pattern (HP:0011008)1.69609838
121Natal tooth (HP:0000695)1.69516968
122Poikiloderma (HP:0001029)1.69302464
123Aplasia/Hypoplasia of the uvula (HP:0010293)1.69112295
124Intestinal fistula (HP:0100819)1.68458281
125Rough bone trabeculation (HP:0100670)1.67119395
126Abnormality of cochlea (HP:0000375)1.66335170
127Asymmetry of the thorax (HP:0001555)1.65424985
128Neoplasm of the adrenal cortex (HP:0100641)1.65201634
129Aplasia/Hypoplasia of the sternum (HP:0006714)1.64581337
130Shallow orbits (HP:0000586)1.64579632
131Deep palmar crease (HP:0006191)1.64256554
132IgA deficiency (HP:0002720)1.63714798
133Vertebral clefting (HP:0008428)1.62859652
134Protrusio acetabuli (HP:0003179)1.61847274
135Cutaneous melanoma (HP:0012056)1.60896031
136Metaphyseal cupping (HP:0003021)1.60198384
137Deep philtrum (HP:0002002)1.60084757
138Acute myeloid leukemia (HP:0004808)1.59985129
139Calcaneovalgus deformity (HP:0001848)1.59830154
140Genu recurvatum (HP:0002816)1.59616701
141Abnormality of the salivary glands (HP:0010286)1.59205092
142Short thumb (HP:0009778)1.59072685
143Trigonocephaly (HP:0000243)1.58692985
144Abnormality of the lower motor neuron (HP:0002366)1.58596010
145Duplication of thumb phalanx (HP:0009942)1.58540137
146Spastic diplegia (HP:0001264)1.58488812
147Flat cornea (HP:0007720)1.57803546
148Abnormality of the distal phalanx of the thumb (HP:0009617)1.57691672
149Arnold-Chiari malformation (HP:0002308)1.57051509
150Entropion (HP:0000621)1.56637544
151Hypoplasia of the capital femoral epiphysis (HP:0003090)1.55911863
152Obsessive-compulsive behavior (HP:0000722)1.55788273
153Abnormal umbilical cord blood vessels (HP:0011403)1.55302051
154Single umbilical artery (HP:0001195)1.55302051
155Abnormality of the fetal cardiovascular system (HP:0010948)1.55302051

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDK124.91610549
2SMG13.76242616
3CDC73.68457214
4EEF2K3.29484044
5MAP3K102.48679345
6NEK22.47706683
7WEE12.30592966
8RPS6KB22.19074760
9BUB12.14128531
10BRD42.10014845
11PKN22.09911992
12EPHA22.09686100
13PBK2.05964013
14TTK1.98551691
15TSSK61.88748402
16ALK1.82836619
17CDK71.80897314
18VRK21.79477137
19PASK1.78722115
20CDK41.75792651
21MST1R1.69066458
22TAF11.67578934
23STK101.67213049
24LATS11.63688797
25TRIB31.60299636
26ICK1.58263533
27IRAK31.51996943
28MTOR1.49848590
29TTN1.48393162
30ATR1.45644143
31PLK11.44797396
32CHEK11.43610840
33MAP4K11.38350346
34NME11.38331483
35AURKB1.35801129
36MKNK21.35305010
37MKNK11.34762118
38SRPK11.33050389
39MAP3K81.29654467
40CDK61.22953379
41CHEK21.18242691
42PRPF4B1.17761525
43ZAK1.15322452
44PAK41.14816171
45PDGFRA1.12639154
46STK31.11049195
47NEK11.10453506
48PIM11.10323352
49BMX1.08707311
50EIF2AK11.08588883
51SCYL21.07609926
52CDK81.06539517
53CDK21.05401963
54PAK21.05279389
55ATM1.05254880
56RPS6KA40.96218305
57FLT30.94931885
58PTK60.93794381
59LATS20.92838913
60LRRK20.92368798
61BRSK20.92078626
62RIPK10.90161228
63TLK10.89018734
64TGFBR10.89000517
65STK40.86014711
66CAMK1D0.84333778
67TYRO30.84196254
68PLK30.82747343
69ACVR1B0.82356165
70CLK10.80362145
71MAP2K30.80214651
72MELK0.77516964
73ERBB40.77151739
74PNCK0.76569769
75SIK10.75658166
76EIF2AK30.73984490
77DDR20.72775749
78FGFR10.72549932
79CDK10.72173498
80CSNK1E0.71469474
81MST40.71314918
82AKT20.69091524
83GRK60.68329548
84DYRK30.67294069
85TAOK20.66916580
86CSNK1D0.66082985
87STK38L0.65696152
88NME20.65359145
89AURKA0.64727546
90CHUK0.63800012
91CSNK2A20.62526343
92CDK90.61706660
93BRSK10.59719566
94JAK30.58207118
95TESK20.57844063
96MAP3K90.57542713
97PLK40.57068247
98EIF2AK20.57043159
99PDGFRB0.56433081
100PRKDC0.56059827
101VRK10.55300292
102MAPK140.51424741
103MAP3K30.51419178
104MAP3K110.49382149
105BRAF0.46573569
106PRKCI0.46241709
107PTK20.46099217
108PAK10.45906617
109MAPK10.44223870
110CAMK1G0.43903414
111CSK0.43224286
112MAPK110.43062014
113PDK20.43058092
114AKT10.42528959
115RPS6KA10.41417397
116CCNB10.39530090
117GSK3B0.38210447
118CSF1R0.37199719
119PIM20.35337565
120RAF10.35138818
121NTRK10.34927290
122FGFR40.33408318
123MET0.33267693
124STK160.32733597
125ZAP700.31695168
126SIK20.31219648
127RPS6KB10.30043464
128MARK30.30042389
129MAP3K140.27892440
130KSR20.27715091
131CSNK2A10.27519046

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.86543518
2DNA replication_Homo sapiens_hsa030303.74673605
3Mismatch repair_Homo sapiens_hsa034303.56305659
4One carbon pool by folate_Homo sapiens_hsa006703.49989958
5RNA transport_Homo sapiens_hsa030133.32710286
6Spliceosome_Homo sapiens_hsa030403.13872549
7Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.74963528
8Cell cycle_Homo sapiens_hsa041102.41123872
9Base excision repair_Homo sapiens_hsa034102.35989415
10Nucleotide excision repair_Homo sapiens_hsa034202.28015607
11mRNA surveillance pathway_Homo sapiens_hsa030152.27204422
12Ribosome_Homo sapiens_hsa030102.23230887
13Homologous recombination_Homo sapiens_hsa034402.05714320
14RNA polymerase_Homo sapiens_hsa030202.00647947
15Fanconi anemia pathway_Homo sapiens_hsa034601.86034682
16RNA degradation_Homo sapiens_hsa030181.72359633
17Lysine degradation_Homo sapiens_hsa003101.58876410
18Non-homologous end-joining_Homo sapiens_hsa034501.56282996
19Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.48889915
20p53 signaling pathway_Homo sapiens_hsa041151.46914437
21Viral carcinogenesis_Homo sapiens_hsa052031.43148347
22MicroRNAs in cancer_Homo sapiens_hsa052061.40532556
23Pyrimidine metabolism_Homo sapiens_hsa002401.36712764
24Systemic lupus erythematosus_Homo sapiens_hsa053221.33915474
25Selenocompound metabolism_Homo sapiens_hsa004501.28869826
26Vitamin B6 metabolism_Homo sapiens_hsa007501.27988392
27Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.27417373
28Small cell lung cancer_Homo sapiens_hsa052221.25959152
29Basal transcription factors_Homo sapiens_hsa030221.18991796
30Cyanoamino acid metabolism_Homo sapiens_hsa004601.16126161
31Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.15673684
32Notch signaling pathway_Homo sapiens_hsa043301.14798370
33HTLV-I infection_Homo sapiens_hsa051661.12630495
34Chronic myeloid leukemia_Homo sapiens_hsa052201.11075635
35Epstein-Barr virus infection_Homo sapiens_hsa051691.09968320
36Basal cell carcinoma_Homo sapiens_hsa052171.08631099
37Biosynthesis of amino acids_Homo sapiens_hsa012301.06487907
38Antigen processing and presentation_Homo sapiens_hsa046121.05635020
39Herpes simplex infection_Homo sapiens_hsa051681.04210012
40Transcriptional misregulation in cancer_Homo sapiens_hsa052020.98807997
41mTOR signaling pathway_Homo sapiens_hsa041500.98802170
42Central carbon metabolism in cancer_Homo sapiens_hsa052300.94255013
43Hippo signaling pathway_Homo sapiens_hsa043900.93435611
44Adherens junction_Homo sapiens_hsa045200.90771103
45Acute myeloid leukemia_Homo sapiens_hsa052210.87878378
46N-Glycan biosynthesis_Homo sapiens_hsa005100.87446092
47TGF-beta signaling pathway_Homo sapiens_hsa043500.82521768
48Thyroid cancer_Homo sapiens_hsa052160.81011146
49Bladder cancer_Homo sapiens_hsa052190.77626360
50Proteoglycans in cancer_Homo sapiens_hsa052050.77164902
51Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.77052081
52Pyruvate metabolism_Homo sapiens_hsa006200.76792405
53NF-kappa B signaling pathway_Homo sapiens_hsa040640.73905674
54Cysteine and methionine metabolism_Homo sapiens_hsa002700.72693344
55Colorectal cancer_Homo sapiens_hsa052100.71859409
56Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.71022094
57Viral myocarditis_Homo sapiens_hsa054160.69470077
58Prostate cancer_Homo sapiens_hsa052150.69215248
59Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.68099736
60Primary immunodeficiency_Homo sapiens_hsa053400.67709234
61Fructose and mannose metabolism_Homo sapiens_hsa000510.66911429
62Proteasome_Homo sapiens_hsa030500.66057910
63Hedgehog signaling pathway_Homo sapiens_hsa043400.65270610
64Pathways in cancer_Homo sapiens_hsa052000.62431992
65Apoptosis_Homo sapiens_hsa042100.61969130
66Thyroid hormone signaling pathway_Homo sapiens_hsa049190.58304931
67Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.58068099
68Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.57438335
69Non-small cell lung cancer_Homo sapiens_hsa052230.57350433
70Hepatitis B_Homo sapiens_hsa051610.55504168
71Oocyte meiosis_Homo sapiens_hsa041140.53888888
72HIF-1 signaling pathway_Homo sapiens_hsa040660.52558440
73Sulfur relay system_Homo sapiens_hsa041220.52401164
74B cell receptor signaling pathway_Homo sapiens_hsa046620.50972124
75Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.50764754
76Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.50727337
77Focal adhesion_Homo sapiens_hsa045100.49239744
78Measles_Homo sapiens_hsa051620.49236560
79T cell receptor signaling pathway_Homo sapiens_hsa046600.48260266
80Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.48066665
81Pentose phosphate pathway_Homo sapiens_hsa000300.47626710
82Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.47580557
83Drug metabolism - other enzymes_Homo sapiens_hsa009830.47549664
84Steroid biosynthesis_Homo sapiens_hsa001000.47349824
85Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.46878628
86Wnt signaling pathway_Homo sapiens_hsa043100.46374209
87Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.44130553
88AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.43907092
89Pancreatic cancer_Homo sapiens_hsa052120.43897961
90Tight junction_Homo sapiens_hsa045300.43811035
91Glioma_Homo sapiens_hsa052140.43754915
92Endometrial cancer_Homo sapiens_hsa052130.42841589
93ErbB signaling pathway_Homo sapiens_hsa040120.42261804
94Purine metabolism_Homo sapiens_hsa002300.40645038
95Galactose metabolism_Homo sapiens_hsa000520.40625112
96PI3K-Akt signaling pathway_Homo sapiens_hsa041510.39496434
97Legionellosis_Homo sapiens_hsa051340.38716479
98Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.37516258
99Insulin signaling pathway_Homo sapiens_hsa049100.37093703
100Shigellosis_Homo sapiens_hsa051310.36727559
101ECM-receptor interaction_Homo sapiens_hsa045120.35765551
102Regulation of actin cytoskeleton_Homo sapiens_hsa048100.35435661
103Leukocyte transendothelial migration_Homo sapiens_hsa046700.34568093
104Folate biosynthesis_Homo sapiens_hsa007900.34143512
105Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.31917848
106Melanoma_Homo sapiens_hsa052180.31441595
1072-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.31377842
108Alcoholism_Homo sapiens_hsa050340.31322160
109Jak-STAT signaling pathway_Homo sapiens_hsa046300.30226604
110Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.29462652
111Longevity regulating pathway - mammal_Homo sapiens_hsa042110.29229970
112Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.28884424
113AMPK signaling pathway_Homo sapiens_hsa041520.27735739
114Influenza A_Homo sapiens_hsa051640.27253837
115Carbon metabolism_Homo sapiens_hsa012000.26819167
116Toxoplasmosis_Homo sapiens_hsa051450.26302788
117VEGF signaling pathway_Homo sapiens_hsa043700.25868128
118Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.25813337
119Renal cell carcinoma_Homo sapiens_hsa052110.25327483

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