Rank | Gene Set | Z-score |
---|---|---|
1 | nuclear pore complex assembly (GO:0051292) | 5.80690828 |
2 | nuclear pore organization (GO:0006999) | 5.72968121 |
3 | folic acid-containing compound biosynthetic process (GO:0009396) | 4.79588433 |
4 | DNA unwinding involved in DNA replication (GO:0006268) | 4.71896831 |
5 | pre-miRNA processing (GO:0031054) | 4.55458467 |
6 | protein localization to kinetochore (GO:0034501) | 4.53944516 |
7 | regulation of posttranscriptional gene silencing (GO:0060147) | 4.41260269 |
8 | regulation of gene silencing by miRNA (GO:0060964) | 4.41260269 |
9 | regulation of gene silencing by RNA (GO:0060966) | 4.41260269 |
10 | pore complex assembly (GO:0046931) | 4.34582419 |
11 | mitotic nuclear envelope disassembly (GO:0007077) | 4.26715692 |
12 | regulation of translational fidelity (GO:0006450) | 4.23138893 |
13 | IMP biosynthetic process (GO:0006188) | 4.09578635 |
14 | heterochromatin organization (GO:0070828) | 4.05774151 |
15 | nuclear envelope disassembly (GO:0051081) | 3.97509369 |
16 | membrane disassembly (GO:0030397) | 3.97509369 |
17 | establishment of integrated proviral latency (GO:0075713) | 3.92580120 |
18 | DNA duplex unwinding (GO:0032508) | 3.88194269 |
19 | DNA geometric change (GO:0032392) | 3.86282774 |
20 | negative regulation of histone methylation (GO:0031061) | 3.79061598 |
21 | DNA replication-dependent nucleosome assembly (GO:0006335) | 3.74827910 |
22 | DNA replication-dependent nucleosome organization (GO:0034723) | 3.74827910 |
23 | proline biosynthetic process (GO:0006561) | 3.69593988 |
24 | formation of translation preinitiation complex (GO:0001731) | 3.69557932 |
25 | regulation of histone H3-K9 methylation (GO:0051570) | 3.69361882 |
26 | chromatin assembly (GO:0031497) | 3.68808393 |
27 | protein complex localization (GO:0031503) | 3.68073365 |
28 | nucleobase biosynthetic process (GO:0046112) | 3.66021811 |
29 | protein localization to chromosome, centromeric region (GO:0071459) | 3.65974183 |
30 | mitotic sister chromatid segregation (GO:0000070) | 3.58196996 |
31 | DNA replication initiation (GO:0006270) | 3.57440975 |
32 | maturation of SSU-rRNA (GO:0030490) | 3.56688286 |
33 | sister chromatid segregation (GO:0000819) | 3.52992422 |
34 | regulation of RNA export from nucleus (GO:0046831) | 3.48256307 |
35 | spliceosomal tri-snRNP complex assembly (GO:0000244) | 3.47941026 |
36 | IMP metabolic process (GO:0046040) | 3.47427513 |
37 | DNA topological change (GO:0006265) | 3.44465015 |
38 | negative regulation of mRNA splicing, via spliceosome (GO:0048025) | 3.43537327 |
39 | DNA strand elongation involved in DNA replication (GO:0006271) | 3.38890122 |
40 | non-recombinational repair (GO:0000726) | 3.36544852 |
41 | double-strand break repair via nonhomologous end joining (GO:0006303) | 3.36544852 |
42 | telomere maintenance via recombination (GO:0000722) | 3.36502833 |
43 | chromosome condensation (GO:0030261) | 3.35104090 |
44 | cellular protein complex localization (GO:0034629) | 3.34843031 |
45 | mitotic chromosome condensation (GO:0007076) | 3.31226882 |
46 | mitotic sister chromatid cohesion (GO:0007064) | 3.27917397 |
47 | dosage compensation (GO:0007549) | 3.27764242 |
48 | regulation of translational termination (GO:0006449) | 3.26434378 |
49 | ribosome assembly (GO:0042255) | 3.24403198 |
50 | DNA strand elongation (GO:0022616) | 3.21709644 |
51 | mitotic recombination (GO:0006312) | 3.20845989 |
52 | ribosome biogenesis (GO:0042254) | 3.19842085 |
53 | mitotic metaphase plate congression (GO:0007080) | 3.19385101 |
54 | positive regulation of chromosome segregation (GO:0051984) | 3.18143324 |
55 | nuclear envelope organization (GO:0006998) | 3.16916278 |
56 | regulation of spindle organization (GO:0090224) | 3.11289378 |
57 | negative regulation of DNA repair (GO:0045738) | 3.10720350 |
58 | regulation of mitotic spindle organization (GO:0060236) | 3.10559169 |
59 | negative regulation of mRNA processing (GO:0050686) | 3.08106197 |
60 | rRNA transcription (GO:0009303) | 3.06962235 |
61 | regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083) | 3.06851997 |
62 | tRNA aminoacylation for protein translation (GO:0006418) | 3.05818701 |
63 | negative regulation of RNA splicing (GO:0033119) | 3.05490554 |
64 | viral transcription (GO:0019083) | 3.05027884 |
65 | DNA synthesis involved in DNA repair (GO:0000731) | 3.04593472 |
66 | ribosomal large subunit biogenesis (GO:0042273) | 3.03701464 |
67 | histone H2A monoubiquitination (GO:0035518) | 3.02175720 |
68 | translational termination (GO:0006415) | 3.01890702 |
69 | paraxial mesoderm development (GO:0048339) | 3.01629430 |
70 | regulation of sister chromatid cohesion (GO:0007063) | 3.01620711 |
71 | amino acid activation (GO:0043038) | 3.00845984 |
72 | tRNA aminoacylation (GO:0043039) | 3.00845984 |
73 | DNA packaging (GO:0006323) | 3.00782097 |
74 | regulation of attachment of spindle microtubules to kinetochore (GO:0051988) | 3.00730310 |
75 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.00724066 |
76 | RNA stabilization (GO:0043489) | 2.99284059 |
77 | mRNA stabilization (GO:0048255) | 2.99284059 |
78 | ribosomal small subunit assembly (GO:0000028) | 2.99119841 |
79 | DNA conformation change (GO:0071103) | 2.99090810 |
80 | protein export from nucleus (GO:0006611) | 2.98696527 |
81 | negative regulation of mRNA metabolic process (GO:1903312) | 2.96135422 |
82 | mRNA transport (GO:0051028) | 2.95915284 |
83 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 2.94875330 |
84 | maturation of 5.8S rRNA (GO:0000460) | 2.93932978 |
85 | mitotic G1 DNA damage checkpoint (GO:0031571) | 2.93487193 |
86 | translational initiation (GO:0006413) | 2.93028170 |
87 | protein-DNA complex disassembly (GO:0032986) | 2.92887309 |
88 | nucleosome disassembly (GO:0006337) | 2.92887309 |
89 | viral mRNA export from host cell nucleus (GO:0046784) | 2.92425199 |
90 | chromatin assembly or disassembly (GO:0006333) | 2.91877156 |
91 | establishment of viral latency (GO:0019043) | 2.90888735 |
92 | histone H4-K12 acetylation (GO:0043983) | 2.90025591 |
93 | positive regulation of cell cycle checkpoint (GO:1901978) | 2.89525316 |
94 | regulation of translational elongation (GO:0006448) | 2.89432464 |
95 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 2.87727338 |
96 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 2.87727338 |
97 | telomere maintenance via semi-conservative replication (GO:0032201) | 2.87601804 |
98 | purine nucleobase biosynthetic process (GO:0009113) | 2.86972885 |
99 | regulation of gene silencing (GO:0060968) | 2.86693868 |
100 | regulation of helicase activity (GO:0051095) | 2.85230386 |
101 | metaphase plate congression (GO:0051310) | 2.84807155 |
102 | tetrahydrofolate metabolic process (GO:0046653) | 2.83819297 |
103 | * rRNA metabolic process (GO:0016072) | 2.83676346 |
104 | regulation of hippo signaling (GO:0035330) | 2.82793523 |
105 | snRNA metabolic process (GO:0016073) | 2.82736902 |
106 | DNA replication checkpoint (GO:0000076) | 2.82266152 |
107 | peptidyl-arginine omega-N-methylation (GO:0035247) | 2.82062807 |
108 | termination of RNA polymerase II transcription (GO:0006369) | 2.80949579 |
109 | histone arginine methylation (GO:0034969) | 2.79704766 |
110 | snRNA processing (GO:0016180) | 2.78707845 |
111 | regulation of centriole replication (GO:0046599) | 2.77888533 |
112 | mitochondrial RNA metabolic process (GO:0000959) | 2.76386417 |
113 | telomere maintenance via telomere lengthening (GO:0010833) | 2.75989182 |
114 | nucleobase-containing small molecule interconversion (GO:0015949) | 2.73379138 |
115 | RNA splicing, via transesterification reactions (GO:0000375) | 2.72730530 |
116 | RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377) | 2.72657155 |
117 | mRNA splicing, via spliceosome (GO:0000398) | 2.72657155 |
118 | translational elongation (GO:0006414) | 2.72342929 |
119 | spliceosomal snRNP assembly (GO:0000387) | 2.71356010 |
120 | negative regulation of chromosome segregation (GO:0051985) | 2.71164115 |
121 | establishment of apical/basal cell polarity (GO:0035089) | 2.70169334 |
122 | alternative mRNA splicing, via spliceosome (GO:0000380) | 2.69850729 |
123 | nucleic acid transport (GO:0050657) | 2.69793418 |
124 | RNA transport (GO:0050658) | 2.69793418 |
125 | establishment of RNA localization (GO:0051236) | 2.69793418 |
126 | regulation of chromosome segregation (GO:0051983) | 2.69784832 |
127 | * rRNA processing (GO:0006364) | 2.69568744 |
128 | trophectodermal cell differentiation (GO:0001829) | 2.69312251 |
129 | ribosomal small subunit biogenesis (GO:0042274) | 2.69174533 |
130 | nuclear-transcribed mRNA poly(A) tail shortening (GO:0000289) | 2.69021808 |
131 | protein localization to chromosome (GO:0034502) | 2.68990626 |
132 | positive regulation of SMAD protein import into nucleus (GO:0060391) | 2.68846979 |
133 | regulation of nucleobase-containing compound transport (GO:0032239) | 2.67986708 |
134 | mitotic G1/S transition checkpoint (GO:0044819) | 2.67831265 |
135 | positive regulation of mitotic metaphase/anaphase transition (GO:0045842) | 2.66400564 |
136 | positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101) | 2.66400564 |
137 | positive regulation of mitotic sister chromatid separation (GO:1901970) | 2.66400564 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 8.78541686 |
2 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 4.63234436 |
3 | * MYC_18555785_ChIP-Seq_MESCs_Mouse | 3.88212032 |
4 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 3.44480159 |
5 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 3.01926200 |
6 | * EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 2.92832053 |
7 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 2.91491777 |
8 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.87869995 |
9 | MYC_22102868_ChIP-Seq_BL_Human | 2.68428710 |
10 | * MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.46201379 |
11 | * KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 2.28746678 |
12 | * MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.09668638 |
13 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 2.06759519 |
14 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 2.04798195 |
15 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.98840188 |
16 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.96866384 |
17 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.92935551 |
18 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 1.90557449 |
19 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 1.90557449 |
20 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 1.90557449 |
21 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.81753027 |
22 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.80809303 |
23 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.77826372 |
24 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.74529314 |
25 | * MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.74337662 |
26 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.68321440 |
27 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.68088753 |
28 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.67941705 |
29 | * ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.67231956 |
30 | * KDM5A_27292631_Chip-Seq_BREAST_Human | 1.60187331 |
31 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.59090532 |
32 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.58602838 |
33 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.56329469 |
34 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.55924087 |
35 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.54217225 |
36 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.50771774 |
37 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.49697064 |
38 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.41099855 |
39 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.41051584 |
40 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.40431722 |
41 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 1.38953798 |
42 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.38394658 |
43 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.38053939 |
44 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.37514698 |
45 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.36638261 |
46 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.36375938 |
47 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.35837925 |
48 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 1.35538797 |
49 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 1.32700480 |
50 | TCF3_18692474_ChIP-Seq_MEFs_Mouse | 1.31890163 |
51 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.31448799 |
52 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 1.30974547 |
53 | * DCP1A_22483619_ChIP-Seq_HELA_Human | 1.30854399 |
54 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.30485254 |
55 | * JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.29611916 |
56 | ZIC3_20872845_ChIP-ChIP_MESCs_Mouse | 1.26947730 |
57 | * TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.26107455 |
58 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.26106711 |
59 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.24980125 |
60 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.24411793 |
61 | * FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.24206126 |
62 | * ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.22548485 |
63 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 1.21963804 |
64 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.21529210 |
65 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 1.20780436 |
66 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.19395271 |
67 | SALL4_18804426_ChIP-ChIP_MESCs_Mouse | 1.17697612 |
68 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 1.17595100 |
69 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.17228552 |
70 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.16833192 |
71 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 1.16541317 |
72 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 1.15972044 |
73 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.15896478 |
74 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.15792552 |
75 | NANOG_21062744_ChIP-ChIP_HESCs_Human | 1.15618101 |
76 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.14739371 |
77 | * GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.14554073 |
78 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.14063724 |
79 | TCF3_18692474_ChIP-Seq_MESCs_Mouse | 1.14055740 |
80 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.13779779 |
81 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.13635841 |
82 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.13260962 |
83 | NACC1_18358816_ChIP-ChIP_MESCs_Mouse | 1.12296386 |
84 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.10648771 |
85 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.10526214 |
86 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 1.10420327 |
87 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.10411890 |
88 | * PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.10325021 |
89 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.08284212 |
90 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 1.08101733 |
91 | * CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.04873302 |
92 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.04584674 |
93 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.03340798 |
94 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.03240600 |
95 | SOX2_18358816_ChIP-ChIP_MESCs_Mouse | 1.01652402 |
96 | CHD1_26751641_Chip-Seq_LNCaP_Human | 1.01056194 |
97 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 0.99900835 |
98 | UTX_26944678_Chip-Seq_JUKART_Human | 0.99453187 |
99 | KDM2B_26808549_Chip-Seq_DND41_Human | 0.99263440 |
100 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 0.98042335 |
101 | * CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.97672466 |
102 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 0.97476713 |
103 | TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 0.97354129 |
104 | ATF3_27146783_Chip-Seq_COLON_Human | 0.96625438 |
105 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 0.95715043 |
106 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 0.95687645 |
107 | POU5F1_16518401_ChIP-PET_MESCs_Mouse | 0.94804455 |
108 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.94770522 |
109 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 0.94184689 |
110 | SREBP1_19666523_ChIP-Seq_LIVER_Mouse | 0.93867830 |
111 | * SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.92947976 |
112 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 0.91631763 |
113 | NCOR1_26117541_ChIP-Seq_K562_Human | 0.90676012 |
114 | SOX17_20123909_ChIP-Seq_XEN_Mouse | 0.90474985 |
115 | MAF_26560356_Chip-Seq_TH1_Human | 0.89748851 |
116 | NANOG_18347094_ChIP-ChIP_MESCs_Mouse | 0.89085210 |
117 | * BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 0.88941798 |
118 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 0.88480163 |
119 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 0.85160527 |
120 | NKX2-5_21415370_ChIP-Seq_HL-1_Mouse | 0.83813063 |
121 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 0.80889357 |
122 | CLOCK_20551151_ChIP-Seq_293T_Human | 0.79398906 |
123 | TBX5_21415370_ChIP-Seq_HL-1_Mouse | 0.79223331 |
124 | * SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 0.78288941 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003111_abnormal_nucleus_morphology | 3.67425179 |
2 | MP0003693_abnormal_embryo_hatching | 3.59612440 |
3 | MP0004957_abnormal_blastocyst_morpholog | 3.56617974 |
4 | MP0008057_abnormal_DNA_replication | 3.54083456 |
5 | MP0010094_abnormal_chromosome_stability | 3.47955655 |
6 | MP0003077_abnormal_cell_cycle | 3.13181682 |
7 | MP0010352_gastrointestinal_tract_polyps | 3.11752949 |
8 | MP0003705_abnormal_hypodermis_morpholog | 2.79569670 |
9 | MP0001730_embryonic_growth_arrest | 2.49033085 |
10 | MP0005076_abnormal_cell_differentiation | 2.35712108 |
11 | MP0010307_abnormal_tumor_latency | 2.25317495 |
12 | MP0000350_abnormal_cell_proliferation | 2.23855617 |
13 | MP0001672_abnormal_embryogenesis/_devel | 2.07316381 |
14 | MP0005380_embryogenesis_phenotype | 2.07316381 |
15 | MP0008007_abnormal_cellular_replicative | 2.06042019 |
16 | MP0008058_abnormal_DNA_repair | 2.02555813 |
17 | MP0004197_abnormal_fetal_growth/weight/ | 2.00712580 |
18 | MP0002084_abnormal_developmental_patter | 2.00276251 |
19 | MP0008932_abnormal_embryonic_tissue | 1.95337432 |
20 | MP0003984_embryonic_growth_retardation | 1.93249046 |
21 | MP0002088_abnormal_embryonic_growth/wei | 1.90653144 |
22 | MP0002396_abnormal_hematopoietic_system | 1.88933678 |
23 | MP0002085_abnormal_embryonic_tissue | 1.86916659 |
24 | MP0002086_abnormal_extraembryonic_tissu | 1.86899782 |
25 | MP0010030_abnormal_orbit_morphology | 1.85843833 |
26 | MP0001697_abnormal_embryo_size | 1.81858704 |
27 | MP0009697_abnormal_copulation | 1.79745865 |
28 | MP0008877_abnormal_DNA_methylation | 1.74329198 |
29 | MP0003123_paternal_imprinting | 1.71526770 |
30 | MP0003890_abnormal_embryonic-extraembry | 1.71415831 |
31 | MP0002080_prenatal_lethality | 1.66058119 |
32 | MP0005451_abnormal_body_composition | 1.51696292 |
33 | MP0003786_premature_aging | 1.48280310 |
34 | MP0001661_extended_life_span | 1.48237034 |
35 | MP0003566_abnormal_cell_adhesion | 1.47118914 |
36 | MP0001293_anophthalmia | 1.42121212 |
37 | MP0002009_preneoplasia | 1.41822014 |
38 | MP0009278_abnormal_bone_marrow | 1.39136091 |
39 | MP0001849_ear_inflammation | 1.38803697 |
40 | MP0004808_abnormal_hematopoietic_stem | 1.38756797 |
41 | MP0003567_abnormal_fetal_cardiomyocyte | 1.38525171 |
42 | MP0003315_abnormal_perineum_morphology | 1.37439125 |
43 | MP0009053_abnormal_anal_canal | 1.35507448 |
44 | MP0000537_abnormal_urethra_morphology | 1.34092560 |
45 | MP0000490_abnormal_crypts_of | 1.34050102 |
46 | MP0002796_impaired_skin_barrier | 1.30641957 |
47 | MP0003121_genomic_imprinting | 1.30331706 |
48 | MP0000579_abnormal_nail_morphology | 1.30302931 |
49 | MP0003119_abnormal_digestive_system | 1.28528488 |
50 | MP0004185_abnormal_adipocyte_glucose | 1.27026344 |
51 | MP0005023_abnormal_wound_healing | 1.26334903 |
52 | MP0002877_abnormal_melanocyte_morpholog | 1.23807717 |
53 | MP0000733_abnormal_muscle_development | 1.19957892 |
54 | MP0000313_abnormal_cell_death | 1.19419352 |
55 | MP0003718_maternal_effect | 1.16984286 |
56 | MP0002019_abnormal_tumor_incidence | 1.16532765 |
57 | MP0002697_abnormal_eye_size | 1.13229504 |
58 | MP0001915_intracranial_hemorrhage | 1.10448574 |
59 | MP0000428_abnormal_craniofacial_morphol | 1.10311060 |
60 | MP0000703_abnormal_thymus_morphology | 1.09248080 |
61 | MP0009672_abnormal_birth_weight | 1.09106439 |
62 | MP0000358_abnormal_cell_content/ | 1.09079303 |
63 | MP0002092_abnormal_eye_morphology | 1.08536366 |
64 | MP0006035_abnormal_mitochondrial_morpho | 1.06605055 |
65 | MP0003385_abnormal_body_wall | 1.06576793 |
66 | MP0004264_abnormal_extraembryonic_tissu | 1.06368817 |
67 | MP0004133_heterotaxia | 1.04003494 |
68 | MP0002111_abnormal_tail_morphology | 1.03373671 |
69 | MP0003221_abnormal_cardiomyocyte_apopto | 1.01841329 |
70 | MP0003937_abnormal_limbs/digits/tail_de | 1.01704364 |
71 | MP0009703_decreased_birth_body | 0.99632743 |
72 | MP0003763_abnormal_thymus_physiology | 0.98621595 |
73 | MP0002060_abnormal_skin_morphology | 0.98474243 |
74 | MP0003300_gastrointestinal_ulcer | 0.97133979 |
75 | MP0009333_abnormal_splenocyte_physiolog | 0.93870874 |
76 | MP0000432_abnormal_head_morphology | 0.93418544 |
77 | MP0002925_abnormal_cardiovascular_devel | 0.92369786 |
78 | MP0003115_abnormal_respiratory_system | 0.92222889 |
79 | MP0001348_abnormal_lacrimal_gland | 0.91900104 |
80 | MP0010234_abnormal_vibrissa_follicle | 0.90149041 |
81 | MP0000762_abnormal_tongue_morphology | 0.90108441 |
82 | MP0003935_abnormal_craniofacial_develop | 0.88927050 |
83 | MP0003283_abnormal_digestive_organ | 0.88457146 |
84 | MP0005623_abnormal_meninges_morphology | 0.88234253 |
85 | MP0004272_abnormal_basement_membrane | 0.88220885 |
86 | MP0001216_abnormal_epidermal_layer | 0.85304055 |
87 | MP0001545_abnormal_hematopoietic_system | 0.84751152 |
88 | MP0005397_hematopoietic_system_phenotyp | 0.84751152 |
89 | MP0002089_abnormal_postnatal_growth/wei | 0.82941970 |
90 | MP0002398_abnormal_bone_marrow | 0.82752862 |
91 | MP0002722_abnormal_immune_system | 0.81491025 |
92 | MP0003806_abnormal_nucleotide_metabolis | 0.80085420 |
93 | MP0000371_diluted_coat_color | 0.78623731 |
94 | MP0005621_abnormal_cell_physiology | 0.77525553 |
95 | MP0000477_abnormal_intestine_morphology | 0.76247084 |
96 | MP0002210_abnormal_sex_determination | 0.76187156 |
97 | MP0003091_abnormal_cell_migration | 0.76051215 |
98 | MP0000689_abnormal_spleen_morphology | 0.75266693 |
99 | MP0001346_abnormal_lacrimal_gland | 0.74383864 |
100 | MP0002249_abnormal_larynx_morphology | 0.74339515 |
101 | MP0003943_abnormal_hepatobiliary_system | 0.74034988 |
102 | MP0002653_abnormal_ependyma_morphology | 0.73980125 |
103 | MP0008770_decreased_survivor_rate | 0.73963395 |
104 | MP0000627_abnormal_mammary_gland | 0.73825643 |
105 | MP0000467_abnormal_esophagus_morphology | 0.73618773 |
106 | MP0001145_abnormal_male_reproductive | 0.73218500 |
107 | MP0004233_abnormal_muscle_weight | 0.73195788 |
108 | MP0005257_abnormal_intraocular_pressure | 0.72250277 |
109 | MP0008260_abnormal_autophagy | 0.72093567 |
110 | MP0003942_abnormal_urinary_system | 0.71860261 |
111 | MP0000678_abnormal_parathyroid_gland | 0.71663909 |
112 | MP0003941_abnormal_skin_development | 0.70375563 |
113 | MP0006292_abnormal_olfactory_placode | 0.69967786 |
114 | MP0002233_abnormal_nose_morphology | 0.69569542 |
115 | MP0001286_abnormal_eye_development | 0.69446561 |
116 | MP0005384_cellular_phenotype | 0.69346219 |
117 | MP0000566_synostosis | 0.68780115 |
118 | MP0000266_abnormal_heart_morphology | 0.68230032 |
119 | MP0002098_abnormal_vibrissa_morphology | 0.68205173 |
120 | MP0001873_stomach_inflammation | 0.68043710 |
121 | MP0000377_abnormal_hair_follicle | 0.66423345 |
122 | MP0003453_abnormal_keratinocyte_physiol | 0.65388120 |
123 | MP0002932_abnormal_joint_morphology | 0.65087935 |
124 | MP0008995_early_reproductive_senescence | 0.62115395 |
125 | MP0010630_abnormal_cardiac_muscle | 0.62092245 |
126 | MP0003861_abnormal_nervous_system | 0.61452807 |
127 | MP0005666_abnormal_adipose_tissue | 0.60635510 |
128 | MP0003755_abnormal_palate_morphology | 0.60424843 |
129 | MP0002075_abnormal_coat/hair_pigmentati | 0.58866269 |
130 | MP0001784_abnormal_fluid_regulation | 0.57938273 |
131 | MP0002429_abnormal_blood_cell | 0.57063809 |
132 | MP0005501_abnormal_skin_physiology | 0.56310847 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Ependymoma (HP:0002888) | 4.31362874 |
2 | Microvesicular hepatic steatosis (HP:0001414) | 3.39648894 |
3 | Progressive muscle weakness (HP:0003323) | 3.36210847 |
4 | Selective tooth agenesis (HP:0001592) | 3.33668655 |
5 | Astrocytoma (HP:0009592) | 3.30237763 |
6 | Abnormality of the astrocytes (HP:0100707) | 3.30237763 |
7 | Multiple enchondromatosis (HP:0005701) | 3.08736229 |
8 | Medulloblastoma (HP:0002885) | 3.06906608 |
9 | Progressive external ophthalmoplegia (HP:0000590) | 2.92851801 |
10 | Deviation of the thumb (HP:0009603) | 2.83743836 |
11 | Proximal placement of thumb (HP:0009623) | 2.75891930 |
12 | Basal cell carcinoma (HP:0002671) | 2.71673564 |
13 | Rhabdomyosarcoma (HP:0002859) | 2.70621650 |
14 | Missing ribs (HP:0000921) | 2.68964767 |
15 | Insomnia (HP:0100785) | 2.68517161 |
16 | Overlapping toe (HP:0001845) | 2.67595666 |
17 | Abnormality of the labia minora (HP:0012880) | 2.63735419 |
18 | Chromsome breakage (HP:0040012) | 2.60609975 |
19 | Glioma (HP:0009733) | 2.60313340 |
20 | Reticulocytopenia (HP:0001896) | 2.59414622 |
21 | Abnormal number of incisors (HP:0011064) | 2.56488230 |
22 | Neoplasm of the oral cavity (HP:0100649) | 2.50846222 |
23 | Neoplasm of striated muscle (HP:0009728) | 2.50548629 |
24 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 2.46168186 |
25 | Colon cancer (HP:0003003) | 2.42993372 |
26 | Abnormality of the preputium (HP:0100587) | 2.42580020 |
27 | Dysmetric saccades (HP:0000641) | 2.39401608 |
28 | Overriding aorta (HP:0002623) | 2.38422372 |
29 | Ulnar bowing (HP:0003031) | 2.37808161 |
30 | Absent thumb (HP:0009777) | 2.37124792 |
31 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.37050687 |
32 | Rib fusion (HP:0000902) | 2.37025504 |
33 | Absent radius (HP:0003974) | 2.30324140 |
34 | Aplasia/hypoplasia of the humerus (HP:0006507) | 2.28550486 |
35 | Impulsivity (HP:0100710) | 2.28280554 |
36 | Increased nuchal translucency (HP:0010880) | 2.25781103 |
37 | Pseudobulbar signs (HP:0002200) | 2.25442422 |
38 | Volvulus (HP:0002580) | 2.25379772 |
39 | Birth length less than 3rd percentile (HP:0003561) | 2.24429545 |
40 | Short humerus (HP:0005792) | 2.24243890 |
41 | Elfin facies (HP:0004428) | 2.22782699 |
42 | Facial cleft (HP:0002006) | 2.21614364 |
43 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 2.17698185 |
44 | Short 4th metacarpal (HP:0010044) | 2.17698185 |
45 | Squamous cell carcinoma (HP:0002860) | 2.17536544 |
46 | Patellar aplasia (HP:0006443) | 2.16102121 |
47 | Nephroblastoma (Wilms tumor) (HP:0002667) | 2.14599235 |
48 | Skin tags (HP:0010609) | 2.13864580 |
49 | Ectopic kidney (HP:0000086) | 2.13852231 |
50 | Aplasia involving forearm bones (HP:0009822) | 2.11630079 |
51 | Absent forearm bone (HP:0003953) | 2.11630079 |
52 | Ankyloglossia (HP:0010296) | 2.11572343 |
53 | 11 pairs of ribs (HP:0000878) | 2.11217739 |
54 | Long eyelashes (HP:0000527) | 2.10657757 |
55 | Urethral obstruction (HP:0000796) | 2.09043743 |
56 | Prominent nose (HP:0000448) | 2.08658835 |
57 | Facial hemangioma (HP:0000329) | 2.07798074 |
58 | Increased density of long bones (HP:0006392) | 2.06002411 |
59 | Preauricular skin tag (HP:0000384) | 2.05862940 |
60 | Heterotopia (HP:0002282) | 2.05089220 |
61 | Abnormality of oral frenula (HP:0000190) | 2.04332797 |
62 | Premature ovarian failure (HP:0008209) | 2.02616646 |
63 | Cerebral aneurysm (HP:0004944) | 2.00186443 |
64 | Hyperacusis (HP:0010780) | 1.99984856 |
65 | Supernumerary ribs (HP:0005815) | 1.99620388 |
66 | Myelodysplasia (HP:0002863) | 1.98892971 |
67 | Biliary tract neoplasm (HP:0100574) | 1.98695438 |
68 | Sandal gap (HP:0001852) | 1.98267773 |
69 | Atresia of the external auditory canal (HP:0000413) | 1.97964582 |
70 | Abnormality of cells of the erythroid lineage (HP:0012130) | 1.97404170 |
71 | Abnormality of chromosome stability (HP:0003220) | 1.97083279 |
72 | Ankle contracture (HP:0006466) | 1.96404820 |
73 | Aplasia/Hypoplasia of the patella (HP:0006498) | 1.95942866 |
74 | Embryonal renal neoplasm (HP:0011794) | 1.95506334 |
75 | Glossoptosis (HP:0000162) | 1.94463752 |
76 | Trismus (HP:0000211) | 1.94388965 |
77 | Renovascular hypertension (HP:0100817) | 1.94290296 |
78 | Spinal muscular atrophy (HP:0007269) | 1.93300248 |
79 | Gastrointestinal carcinoma (HP:0002672) | 1.93231722 |
80 | Malignant gastrointestinal tract tumors (HP:0006749) | 1.93231722 |
81 | Agnosia (HP:0010524) | 1.92962398 |
82 | Abnormality of the fingertips (HP:0001211) | 1.92191519 |
83 | Sparse lateral eyebrow (HP:0005338) | 1.91715975 |
84 | Supernumerary bones of the axial skeleton (HP:0009144) | 1.91672534 |
85 | Cafe-au-lait spot (HP:0000957) | 1.89904496 |
86 | Abnormal number of erythroid precursors (HP:0012131) | 1.89822302 |
87 | Amaurosis fugax (HP:0100576) | 1.89469724 |
88 | Choanal atresia (HP:0000453) | 1.87666119 |
89 | Vertebral arch anomaly (HP:0008438) | 1.87201614 |
90 | Horseshoe kidney (HP:0000085) | 1.86693187 |
91 | Anal stenosis (HP:0002025) | 1.86542210 |
92 | Ragged-red muscle fibers (HP:0003200) | 1.85270642 |
93 | Broad thumb (HP:0011304) | 1.85063646 |
94 | Abnormality of the carotid arteries (HP:0005344) | 1.84562724 |
95 | Breast hypoplasia (HP:0003187) | 1.82923615 |
96 | Esophageal atresia (HP:0002032) | 1.82566623 |
97 | Skull defect (HP:0001362) | 1.82098717 |
98 | Progressive hearing impairment (HP:0001730) | 1.81927994 |
99 | High anterior hairline (HP:0009890) | 1.81854355 |
100 | Cortical dysplasia (HP:0002539) | 1.81358719 |
101 | Renal duplication (HP:0000075) | 1.80525210 |
102 | Abnormality of the umbilical cord (HP:0010881) | 1.80096681 |
103 | Back pain (HP:0003418) | 1.79824752 |
104 | High pitched voice (HP:0001620) | 1.79366870 |
105 | Small intestinal stenosis (HP:0012848) | 1.79104023 |
106 | Duodenal stenosis (HP:0100867) | 1.79104023 |
107 | Meckel diverticulum (HP:0002245) | 1.75827608 |
108 | Long palpebral fissure (HP:0000637) | 1.75764213 |
109 | Vertebral fusion (HP:0002948) | 1.75345011 |
110 | Patellar dislocation (HP:0002999) | 1.75159576 |
111 | Abnormality of the calcaneus (HP:0008364) | 1.75065061 |
112 | Abnormality of the anterior horn cell (HP:0006802) | 1.73899321 |
113 | Degeneration of anterior horn cells (HP:0002398) | 1.73899321 |
114 | Hypopigmentation of the fundus (HP:0007894) | 1.73710114 |
115 | Abnormality of the ileum (HP:0001549) | 1.73438330 |
116 | Neoplasm of the pancreas (HP:0002894) | 1.72514586 |
117 | Abnormality of the antihelix (HP:0009738) | 1.72507831 |
118 | Diastasis recti (HP:0001540) | 1.71907655 |
119 | Termporal pattern (HP:0011008) | 1.69609838 |
120 | Insidious onset (HP:0003587) | 1.69609838 |
121 | Natal tooth (HP:0000695) | 1.69516968 |
122 | Poikiloderma (HP:0001029) | 1.69302464 |
123 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.69112295 |
124 | Intestinal fistula (HP:0100819) | 1.68458281 |
125 | Rough bone trabeculation (HP:0100670) | 1.67119395 |
126 | Abnormality of cochlea (HP:0000375) | 1.66335170 |
127 | Asymmetry of the thorax (HP:0001555) | 1.65424985 |
128 | Neoplasm of the adrenal cortex (HP:0100641) | 1.65201634 |
129 | Aplasia/Hypoplasia of the sternum (HP:0006714) | 1.64581337 |
130 | Shallow orbits (HP:0000586) | 1.64579632 |
131 | Deep palmar crease (HP:0006191) | 1.64256554 |
132 | IgA deficiency (HP:0002720) | 1.63714798 |
133 | Vertebral clefting (HP:0008428) | 1.62859652 |
134 | Protrusio acetabuli (HP:0003179) | 1.61847274 |
135 | Cutaneous melanoma (HP:0012056) | 1.60896031 |
136 | Metaphyseal cupping (HP:0003021) | 1.60198384 |
137 | Deep philtrum (HP:0002002) | 1.60084757 |
138 | Acute myeloid leukemia (HP:0004808) | 1.59985129 |
139 | Calcaneovalgus deformity (HP:0001848) | 1.59830154 |
140 | Genu recurvatum (HP:0002816) | 1.59616701 |
141 | Abnormality of the salivary glands (HP:0010286) | 1.59205092 |
142 | Short thumb (HP:0009778) | 1.59072685 |
143 | Trigonocephaly (HP:0000243) | 1.58692985 |
144 | Abnormality of the lower motor neuron (HP:0002366) | 1.58596010 |
145 | Duplication of thumb phalanx (HP:0009942) | 1.58540137 |
146 | Spastic diplegia (HP:0001264) | 1.58488812 |
147 | Flat cornea (HP:0007720) | 1.57803546 |
148 | Abnormality of the distal phalanx of the thumb (HP:0009617) | 1.57691672 |
149 | Arnold-Chiari malformation (HP:0002308) | 1.57051509 |
150 | Entropion (HP:0000621) | 1.56637544 |
151 | Hypoplasia of the capital femoral epiphysis (HP:0003090) | 1.55911863 |
152 | Obsessive-compulsive behavior (HP:0000722) | 1.55788273 |
153 | Abnormality of the fetal cardiovascular system (HP:0010948) | 1.55302051 |
154 | Abnormal umbilical cord blood vessels (HP:0011403) | 1.55302051 |
155 | Single umbilical artery (HP:0001195) | 1.55302051 |
Rank | Gene Set | Z-score |
---|---|---|
1 | CDK12 | 4.91610549 |
2 | SMG1 | 3.76242616 |
3 | CDC7 | 3.68457214 |
4 | EEF2K | 3.29484044 |
5 | MAP3K10 | 2.48679345 |
6 | NEK2 | 2.47706683 |
7 | WEE1 | 2.30592966 |
8 | RPS6KB2 | 2.19074760 |
9 | BUB1 | 2.14128531 |
10 | BRD4 | 2.10014845 |
11 | PKN2 | 2.09911992 |
12 | EPHA2 | 2.09686100 |
13 | PBK | 2.05964013 |
14 | TTK | 1.98551691 |
15 | TSSK6 | 1.88748402 |
16 | ALK | 1.82836619 |
17 | CDK7 | 1.80897314 |
18 | VRK2 | 1.79477137 |
19 | PASK | 1.78722115 |
20 | CDK4 | 1.75792651 |
21 | MST1R | 1.69066458 |
22 | TAF1 | 1.67578934 |
23 | STK10 | 1.67213049 |
24 | LATS1 | 1.63688797 |
25 | TRIB3 | 1.60299636 |
26 | ICK | 1.58263533 |
27 | IRAK3 | 1.51996943 |
28 | MTOR | 1.49848590 |
29 | TTN | 1.48393162 |
30 | ATR | 1.45644143 |
31 | PLK1 | 1.44797396 |
32 | CHEK1 | 1.43610840 |
33 | MAP4K1 | 1.38350346 |
34 | NME1 | 1.38331483 |
35 | AURKB | 1.35801129 |
36 | MKNK2 | 1.35305010 |
37 | MKNK1 | 1.34762118 |
38 | SRPK1 | 1.33050389 |
39 | MAP3K8 | 1.29654467 |
40 | CDK6 | 1.22953379 |
41 | CHEK2 | 1.18242691 |
42 | PRPF4B | 1.17761525 |
43 | ZAK | 1.15322452 |
44 | PAK4 | 1.14816171 |
45 | PDGFRA | 1.12639154 |
46 | STK3 | 1.11049195 |
47 | NEK1 | 1.10453506 |
48 | PIM1 | 1.10323352 |
49 | BMX | 1.08707311 |
50 | EIF2AK1 | 1.08588883 |
51 | SCYL2 | 1.07609926 |
52 | CDK8 | 1.06539517 |
53 | CDK2 | 1.05401963 |
54 | PAK2 | 1.05279389 |
55 | ATM | 1.05254880 |
56 | RPS6KA4 | 0.96218305 |
57 | FLT3 | 0.94931885 |
58 | PTK6 | 0.93794381 |
59 | LATS2 | 0.92838913 |
60 | LRRK2 | 0.92368798 |
61 | BRSK2 | 0.92078626 |
62 | RIPK1 | 0.90161228 |
63 | TLK1 | 0.89018734 |
64 | TGFBR1 | 0.89000517 |
65 | STK4 | 0.86014711 |
66 | CAMK1D | 0.84333778 |
67 | TYRO3 | 0.84196254 |
68 | PLK3 | 0.82747343 |
69 | ACVR1B | 0.82356165 |
70 | CLK1 | 0.80362145 |
71 | MAP2K3 | 0.80214651 |
72 | MELK | 0.77516964 |
73 | ERBB4 | 0.77151739 |
74 | PNCK | 0.76569769 |
75 | SIK1 | 0.75658166 |
76 | EIF2AK3 | 0.73984490 |
77 | DDR2 | 0.72775749 |
78 | FGFR1 | 0.72549932 |
79 | CDK1 | 0.72173498 |
80 | CSNK1E | 0.71469474 |
81 | MST4 | 0.71314918 |
82 | AKT2 | 0.69091524 |
83 | GRK6 | 0.68329548 |
84 | DYRK3 | 0.67294069 |
85 | TAOK2 | 0.66916580 |
86 | CSNK1D | 0.66082985 |
87 | STK38L | 0.65696152 |
88 | NME2 | 0.65359145 |
89 | AURKA | 0.64727546 |
90 | CHUK | 0.63800012 |
91 | CSNK2A2 | 0.62526343 |
92 | CDK9 | 0.61706660 |
93 | BRSK1 | 0.59719566 |
94 | JAK3 | 0.58207118 |
95 | TESK2 | 0.57844063 |
96 | MAP3K9 | 0.57542713 |
97 | PLK4 | 0.57068247 |
98 | EIF2AK2 | 0.57043159 |
99 | PDGFRB | 0.56433081 |
100 | PRKDC | 0.56059827 |
101 | VRK1 | 0.55300292 |
102 | MAPK14 | 0.51424741 |
103 | MAP3K3 | 0.51419178 |
104 | MAP3K11 | 0.49382149 |
105 | BRAF | 0.46573569 |
106 | PRKCI | 0.46241709 |
107 | PTK2 | 0.46099217 |
108 | PAK1 | 0.45906617 |
109 | MAPK1 | 0.44223870 |
110 | CAMK1G | 0.43903414 |
111 | CSK | 0.43224286 |
112 | MAPK11 | 0.43062014 |
113 | PDK2 | 0.43058092 |
114 | AKT1 | 0.42528959 |
115 | RPS6KA1 | 0.41417397 |
116 | CCNB1 | 0.39530090 |
117 | GSK3B | 0.38210447 |
118 | CSF1R | 0.37199719 |
119 | PIM2 | 0.35337565 |
120 | RAF1 | 0.35138818 |
121 | NTRK1 | 0.34927290 |
122 | FGFR4 | 0.33408318 |
123 | MET | 0.33267693 |
124 | STK16 | 0.32733597 |
125 | ZAP70 | 0.31695168 |
126 | SIK2 | 0.31219648 |
127 | RPS6KB1 | 0.30043464 |
128 | MARK3 | 0.30042389 |
129 | MAP3K14 | 0.27892440 |
130 | KSR2 | 0.27715091 |
131 | CSNK2A1 | 0.27519046 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 3.86543518 |
2 | DNA replication_Homo sapiens_hsa03030 | 3.74673605 |
3 | Mismatch repair_Homo sapiens_hsa03430 | 3.56305659 |
4 | One carbon pool by folate_Homo sapiens_hsa00670 | 3.49989958 |
5 | RNA transport_Homo sapiens_hsa03013 | 3.32710286 |
6 | Spliceosome_Homo sapiens_hsa03040 | 3.13872549 |
7 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 2.74963528 |
8 | Cell cycle_Homo sapiens_hsa04110 | 2.41123872 |
9 | Base excision repair_Homo sapiens_hsa03410 | 2.35989415 |
10 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.28015607 |
11 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 2.27204422 |
12 | Ribosome_Homo sapiens_hsa03010 | 2.23230887 |
13 | Homologous recombination_Homo sapiens_hsa03440 | 2.05714320 |
14 | RNA polymerase_Homo sapiens_hsa03020 | 2.00647947 |
15 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.86034682 |
16 | RNA degradation_Homo sapiens_hsa03018 | 1.72359633 |
17 | Lysine degradation_Homo sapiens_hsa00310 | 1.58876410 |
18 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.56282996 |
19 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.48889915 |
20 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.46914437 |
21 | Viral carcinogenesis_Homo sapiens_hsa05203 | 1.43148347 |
22 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 1.40532556 |
23 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.36712764 |
24 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.33915474 |
25 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.28869826 |
26 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.27988392 |
27 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 1.27417373 |
28 | Small cell lung cancer_Homo sapiens_hsa05222 | 1.25959152 |
29 | Basal transcription factors_Homo sapiens_hsa03022 | 1.18991796 |
30 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.16126161 |
31 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 1.15673684 |
32 | Notch signaling pathway_Homo sapiens_hsa04330 | 1.14798370 |
33 | HTLV-I infection_Homo sapiens_hsa05166 | 1.12630495 |
34 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.11075635 |
35 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 1.09968320 |
36 | Basal cell carcinoma_Homo sapiens_hsa05217 | 1.08631099 |
37 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.06487907 |
38 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.05635020 |
39 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.04210012 |
40 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.98807997 |
41 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.98802170 |
42 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.94255013 |
43 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.93435611 |
44 | Adherens junction_Homo sapiens_hsa04520 | 0.90771103 |
45 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.87878378 |
46 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.87446092 |
47 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.82521768 |
48 | Thyroid cancer_Homo sapiens_hsa05216 | 0.81011146 |
49 | Bladder cancer_Homo sapiens_hsa05219 | 0.77626360 |
50 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.77164902 |
51 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.77052081 |
52 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.76792405 |
53 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.73905674 |
54 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.72693344 |
55 | Colorectal cancer_Homo sapiens_hsa05210 | 0.71859409 |
56 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.71022094 |
57 | Viral myocarditis_Homo sapiens_hsa05416 | 0.69470077 |
58 | Prostate cancer_Homo sapiens_hsa05215 | 0.69215248 |
59 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.68099736 |
60 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.67709234 |
61 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.66911429 |
62 | Proteasome_Homo sapiens_hsa03050 | 0.66057910 |
63 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.65270610 |
64 | Pathways in cancer_Homo sapiens_hsa05200 | 0.62431992 |
65 | Apoptosis_Homo sapiens_hsa04210 | 0.61969130 |
66 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.58304931 |
67 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.58068099 |
68 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.57438335 |
69 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.57350433 |
70 | Hepatitis B_Homo sapiens_hsa05161 | 0.55504168 |
71 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.53888888 |
72 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.52558440 |
73 | Sulfur relay system_Homo sapiens_hsa04122 | 0.52401164 |
74 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.50972124 |
75 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.50764754 |
76 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.50727337 |
77 | Focal adhesion_Homo sapiens_hsa04510 | 0.49239744 |
78 | Measles_Homo sapiens_hsa05162 | 0.49236560 |
79 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.48260266 |
80 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.48066665 |
81 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.47626710 |
82 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.47580557 |
83 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.47549664 |
84 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.47349824 |
85 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.46878628 |
86 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.46374209 |
87 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.44130553 |
88 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.43907092 |
89 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.43897961 |
90 | Tight junction_Homo sapiens_hsa04530 | 0.43811035 |
91 | Glioma_Homo sapiens_hsa05214 | 0.43754915 |
92 | Endometrial cancer_Homo sapiens_hsa05213 | 0.42841589 |
93 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.42261804 |
94 | Purine metabolism_Homo sapiens_hsa00230 | 0.40645038 |
95 | Galactose metabolism_Homo sapiens_hsa00052 | 0.40625112 |
96 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.39496434 |
97 | Legionellosis_Homo sapiens_hsa05134 | 0.38716479 |
98 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.37516258 |
99 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.37093703 |
100 | Shigellosis_Homo sapiens_hsa05131 | 0.36727559 |
101 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.35765551 |
102 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.35435661 |
103 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.34568093 |
104 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.34143512 |
105 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.31917848 |
106 | Melanoma_Homo sapiens_hsa05218 | 0.31441595 |
107 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.31377842 |
108 | Alcoholism_Homo sapiens_hsa05034 | 0.31322160 |
109 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.30226604 |
110 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.29462652 |
111 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.29229970 |
112 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.28884424 |
113 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.27735739 |
114 | Influenza A_Homo sapiens_hsa05164 | 0.27253837 |
115 | Carbon metabolism_Homo sapiens_hsa01200 | 0.26819167 |
116 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.26302788 |
117 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.25868128 |
118 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.25813337 |
119 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.25327483 |