

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | otic vesicle formation (GO:0030916) | 9.62453683 |
| 2 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 6.47660084 |
| 3 | limb bud formation (GO:0060174) | 6.01942401 |
| 4 | chaperone-mediated protein transport (GO:0072321) | 5.80509446 |
| 5 | maturation of SSU-rRNA (GO:0030490) | 5.77784823 |
| 6 | prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis (GO:006052 | 5.54754259 |
| 7 | viral transcription (GO:0019083) | 5.54491634 |
| 8 | ribosomal small subunit biogenesis (GO:0042274) | 5.28082721 |
| 9 | translational termination (GO:0006415) | 5.23807908 |
| 10 | regulation of branching involved in prostate gland morphogenesis (GO:0060687) | 5.08192041 |
| 11 | ribosomal small subunit assembly (GO:0000028) | 5.00924274 |
| 12 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.88685639 |
| 13 | ATP synthesis coupled proton transport (GO:0015986) | 4.79696182 |
| 14 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.79696182 |
| 15 | lens fiber cell development (GO:0070307) | 4.76370732 |
| 16 | central nervous system myelination (GO:0022010) | 4.53303353 |
| 17 | axon ensheathment in central nervous system (GO:0032291) | 4.53303353 |
| 18 | translational elongation (GO:0006414) | 4.44096741 |
| 19 | cysteine metabolic process (GO:0006534) | 4.41796138 |
| 20 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 4.34964295 |
| 21 | protein targeting to ER (GO:0045047) | 4.30489501 |
| 22 | cotranslational protein targeting to membrane (GO:0006613) | 4.29516628 |
| 23 | behavioral response to nicotine (GO:0035095) | 4.24527060 |
| 24 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 4.12098394 |
| 25 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 4.08731203 |
| 26 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 4.08731203 |
| 27 | NADH dehydrogenase complex assembly (GO:0010257) | 4.08731203 |
| 28 | protein localization to endoplasmic reticulum (GO:0070972) | 4.01936972 |
| 29 | viral life cycle (GO:0019058) | 4.01414130 |
| 30 | protein complex biogenesis (GO:0070271) | 3.98101547 |
| 31 | pattern specification involved in kidney development (GO:0061004) | 3.97486323 |
| 32 | protein neddylation (GO:0045116) | 3.91091277 |
| 33 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.89171368 |
| 34 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.89171368 |
| 35 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.89112771 |
| 36 | GTP biosynthetic process (GO:0006183) | 3.86977130 |
| 37 | lung-associated mesenchyme development (GO:0060484) | 3.86262596 |
| 38 | lateral sprouting from an epithelium (GO:0060601) | 3.80470823 |
| 39 | cellular protein complex disassembly (GO:0043624) | 3.77300431 |
| 40 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.74632772 |
| 41 | heart valve formation (GO:0003188) | 3.74513077 |
| 42 | epithelial to mesenchymal transition involved in endocardial cushion formation (GO:0003198) | 3.61569637 |
| 43 | translational initiation (GO:0006413) | 3.59803053 |
| 44 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.54063978 |
| 45 | respiratory electron transport chain (GO:0022904) | 3.53903055 |
| 46 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.52244832 |
| 47 | digestive tract morphogenesis (GO:0048546) | 3.49928300 |
| 48 | electron transport chain (GO:0022900) | 3.49910461 |
| 49 | positive regulation of mitochondrial membrane permeability involved in apoptotic process (GO:1902110 | 3.47694054 |
| 50 | mitochondrial outer membrane permeabilization involved in programmed cell death (GO:1902686) | 3.47694054 |
| 51 | cellular component biogenesis (GO:0044085) | 3.45964311 |
| 52 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.45653119 |
| 53 | homocysteine metabolic process (GO:0050667) | 3.42388442 |
| 54 | forebrain neuron development (GO:0021884) | 3.32456556 |
| 55 | lung lobe morphogenesis (GO:0060463) | 3.30159809 |
| 56 | intracellular protein transmembrane import (GO:0044743) | 3.27351667 |
| 57 | UTP biosynthetic process (GO:0006228) | 3.22948653 |
| 58 | ribosomal large subunit biogenesis (GO:0042273) | 3.15660952 |
| 59 | branching involved in salivary gland morphogenesis (GO:0060445) | 3.14180521 |
| 60 | presynaptic membrane assembly (GO:0097105) | 3.13346062 |
| 61 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 3.12534570 |
| 62 | prostate gland growth (GO:0060736) | 3.12364417 |
| 63 | cochlea development (GO:0090102) | 3.12189448 |
| 64 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 3.11593333 |
| 65 | pseudouridine synthesis (GO:0001522) | 3.11554006 |
| 66 | photoreceptor cell differentiation (GO:0046530) | 3.08468776 |
| 67 | eye photoreceptor cell differentiation (GO:0001754) | 3.08468776 |
| 68 | signal peptide processing (GO:0006465) | 3.07674177 |
| 69 | protein complex disassembly (GO:0043241) | 3.07590626 |
| 70 | cranial suture morphogenesis (GO:0060363) | 3.05887898 |
| 71 | guanosine-containing compound biosynthetic process (GO:1901070) | 3.05783894 |
| 72 | appendage development (GO:0048736) | 3.03456658 |
| 73 | limb development (GO:0060173) | 3.03456658 |
| 74 | translation (GO:0006412) | 3.01773536 |
| 75 | ribosome biogenesis (GO:0042254) | 3.00595202 |
| 76 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 2.99529556 |
| 77 | negative regulation of astrocyte differentiation (GO:0048712) | 2.98754765 |
| 78 | macromolecular complex disassembly (GO:0032984) | 2.89995287 |
| 79 | ATP biosynthetic process (GO:0006754) | 2.89026394 |
| 80 | protein targeting to membrane (GO:0006612) | 2.88940181 |
| 81 | CTP metabolic process (GO:0046036) | 2.87625140 |
| 82 | CTP biosynthetic process (GO:0006241) | 2.87625140 |
| 83 | neuronal stem cell maintenance (GO:0097150) | 2.86936175 |
| 84 | purine nucleotide salvage (GO:0032261) | 2.83619724 |
| 85 | nephron tubule formation (GO:0072079) | 2.83043569 |
| 86 | UTP metabolic process (GO:0046051) | 2.82046915 |
| 87 | central nervous system neuron development (GO:0021954) | 2.81534373 |
| 88 | branching involved in prostate gland morphogenesis (GO:0060442) | 2.78558253 |
| 89 | regulation of mitochondrial translation (GO:0070129) | 2.78244536 |
| 90 | rRNA processing (GO:0006364) | 2.77647454 |
| 91 | male meiosis I (GO:0007141) | 2.76585940 |
| 92 | chaperone-mediated protein complex assembly (GO:0051131) | 2.75517466 |
| 93 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 2.75486380 |
| 94 | positive regulation of RNA splicing (GO:0033120) | 2.75428509 |
| 95 | negative regulation of membrane potential (GO:0045837) | 2.74511681 |
| 96 | presynaptic membrane organization (GO:0097090) | 2.72165185 |
| 97 | rRNA metabolic process (GO:0016072) | 2.70990103 |
| 98 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 2.70619814 |
| 99 | tongue development (GO:0043586) | 2.69425901 |
| 100 | cell proliferation in forebrain (GO:0021846) | 2.67867618 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EZH2_22144423_ChIP-Seq_EOC_Human | 5.43074925 |
| 2 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.30560906 |
| 3 | VDR_22108803_ChIP-Seq_LS180_Human | 3.12900347 |
| 4 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.88250968 |
| 5 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 2.81036253 |
| 6 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.78657144 |
| 7 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.77855685 |
| 8 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 2.72643692 |
| 9 | FUS_26573619_Chip-Seq_HEK293_Human | 2.52927256 |
| 10 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 2.38424728 |
| 11 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.33678225 |
| 12 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 2.33421720 |
| 13 | RNF2_27304074_Chip-Seq_NSC_Mouse | 2.30138052 |
| 14 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 2.27953294 |
| 15 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.27742745 |
| 16 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.23182552 |
| 17 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.16576459 |
| 18 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 2.16071303 |
| 19 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.12527025 |
| 20 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 2.12279151 |
| 21 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.10477337 |
| 22 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 2.08884930 |
| 23 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 2.08752973 |
| 24 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.94087412 |
| 25 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.91457347 |
| 26 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.91457347 |
| 27 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.90698507 |
| 28 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.87998146 |
| 29 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.84521803 |
| 30 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.82537399 |
| 31 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.81882938 |
| 32 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.80405569 |
| 33 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.77837213 |
| 34 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.77386258 |
| 35 | EWS_26573619_Chip-Seq_HEK293_Human | 1.77261095 |
| 36 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.76283066 |
| 37 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.69355070 |
| 38 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.62371598 |
| 39 | P300_19829295_ChIP-Seq_ESCs_Human | 1.61239455 |
| 40 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.57645860 |
| 41 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.55678252 |
| 42 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.54352461 |
| 43 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.53397609 |
| 44 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 1.53326926 |
| 45 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.47287339 |
| 46 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.46795400 |
| 47 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.46679205 |
| 48 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.35809830 |
| 49 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.29020229 |
| 50 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.28616985 |
| 51 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.28386256 |
| 52 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.26527819 |
| 53 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.25645680 |
| 54 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.24328854 |
| 55 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.24148303 |
| 56 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.23839064 |
| 57 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.23379310 |
| 58 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.22243581 |
| 59 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.21529039 |
| 60 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.20364724 |
| 61 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.18793639 |
| 62 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.16871149 |
| 63 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.14287664 |
| 64 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 1.14192169 |
| 65 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.13921049 |
| 66 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.13655206 |
| 67 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.10776119 |
| 68 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.10609632 |
| 69 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.10102191 |
| 70 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.09851798 |
| 71 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.09851798 |
| 72 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.09060155 |
| 73 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.09060155 |
| 74 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.08527501 |
| 75 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.07677250 |
| 76 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.06424865 |
| 77 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.03635628 |
| 78 | NCOR_22424771_ChIP-Seq_293T_Human | 1.01755194 |
| 79 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 0.98301344 |
| 80 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.97864274 |
| 81 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 0.97162194 |
| 82 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 0.96169077 |
| 83 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.95724461 |
| 84 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 0.95326889 |
| 85 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.94640166 |
| 86 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 0.94261722 |
| 87 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 0.93495233 |
| 88 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.93169076 |
| 89 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.92986661 |
| 90 | MYC_18940864_ChIP-ChIP_HL60_Human | 0.92804842 |
| 91 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 0.92290021 |
| 92 | CEBPB_26923725_Chip-Seq_MESODERM_Mouse | 0.91646164 |
| 93 | ER_23166858_ChIP-Seq_MCF-7_Human | 0.90474354 |
| 94 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 0.89814537 |
| 95 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 0.89321718 |
| 96 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.87546920 |
| 97 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.87546920 |
| 98 | TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse | 0.87387916 |
| 99 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 0.86215900 |
| 100 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 0.85640802 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0000566_synostosis | 8.21173723 |
| 2 | MP0003136_yellow_coat_color | 5.02668203 |
| 3 | MP0006292_abnormal_olfactory_placode | 3.53288056 |
| 4 | MP0005670_abnormal_white_adipose | 3.34720090 |
| 5 | MP0000537_abnormal_urethra_morphology | 3.04947103 |
| 6 | MP0010030_abnormal_orbit_morphology | 2.58654453 |
| 7 | MP0002282_abnormal_trachea_morphology | 2.24696415 |
| 8 | MP0009379_abnormal_foot_pigmentation | 2.18367244 |
| 9 | MP0001346_abnormal_lacrimal_gland | 2.09357829 |
| 10 | MP0002249_abnormal_larynx_morphology | 1.97783904 |
| 11 | MP0002089_abnormal_postnatal_growth/wei | 1.92591607 |
| 12 | MP0002638_abnormal_pupillary_reflex | 1.91578457 |
| 13 | MP0004885_abnormal_endolymph | 1.89629051 |
| 14 | MP0004142_abnormal_muscle_tone | 1.84210334 |
| 15 | MP0009780_abnormal_chondrocyte_physiolo | 1.79095010 |
| 16 | MP0000631_abnormal_neuroendocrine_gland | 1.76292049 |
| 17 | MP0000049_abnormal_middle_ear | 1.75074040 |
| 18 | MP0001299_abnormal_eye_distance/ | 1.68468325 |
| 19 | MP0003122_maternal_imprinting | 1.57063784 |
| 20 | MP0002837_dystrophic_cardiac_calcinosis | 1.54835727 |
| 21 | MP0002160_abnormal_reproductive_system | 1.54518159 |
| 22 | MP0005083_abnormal_biliary_tract | 1.52995544 |
| 23 | MP0000762_abnormal_tongue_morphology | 1.52576842 |
| 24 | MP0009250_abnormal_appendicular_skeleto | 1.51444214 |
| 25 | MP0002736_abnormal_nociception_after | 1.51415275 |
| 26 | MP0002938_white_spotting | 1.51064311 |
| 27 | MP0000647_abnormal_sebaceous_gland | 1.50745302 |
| 28 | MP0005646_abnormal_pituitary_gland | 1.46862700 |
| 29 | MP0003938_abnormal_ear_development | 1.44365392 |
| 30 | MP0001293_anophthalmia | 1.37901400 |
| 31 | MP0004134_abnormal_chest_morphology | 1.35350787 |
| 32 | MP0001440_abnormal_grooming_behavior | 1.32022139 |
| 33 | MP0002108_abnormal_muscle_morphology | 1.25624453 |
| 34 | MP0000428_abnormal_craniofacial_morphol | 1.23987827 |
| 35 | MP0004145_abnormal_muscle_electrophysio | 1.23868592 |
| 36 | MP0008877_abnormal_DNA_methylation | 1.23239593 |
| 37 | MP0000383_abnormal_hair_follicle | 1.22222159 |
| 38 | MP0002163_abnormal_gland_morphology | 1.21229038 |
| 39 | MP0003646_muscle_fatigue | 1.20756430 |
| 40 | MP0002653_abnormal_ependyma_morphology | 1.20600260 |
| 41 | MP0008995_early_reproductive_senescence | 1.20154303 |
| 42 | MP0000026_abnormal_inner_ear | 1.19099607 |
| 43 | MP0005377_hearing/vestibular/ear_phenot | 1.17566488 |
| 44 | MP0003878_abnormal_ear_physiology | 1.17566488 |
| 45 | MP0009053_abnormal_anal_canal | 1.16820712 |
| 46 | MP0001968_abnormal_touch/_nociception | 1.15349786 |
| 47 | MP0002277_abnormal_respiratory_mucosa | 1.14680603 |
| 48 | MP0003937_abnormal_limbs/digits/tail_de | 1.13759503 |
| 49 | MP0000579_abnormal_nail_morphology | 1.12797758 |
| 50 | MP0003755_abnormal_palate_morphology | 1.12511991 |
| 51 | MP0000778_abnormal_nervous_system | 1.08667901 |
| 52 | MP0005503_abnormal_tendon_morphology | 1.06784556 |
| 53 | MP0005379_endocrine/exocrine_gland_phen | 1.06590224 |
| 54 | MP0002095_abnormal_skin_pigmentation | 1.05540837 |
| 55 | MP0005187_abnormal_penis_morphology | 1.05444252 |
| 56 | MP0000534_abnormal_ureter_morphology | 1.04996099 |
| 57 | MP0005389_reproductive_system_phenotype | 1.02334077 |
| 58 | MP0003890_abnormal_embryonic-extraembry | 0.94546206 |
| 59 | MP0002735_abnormal_chemical_nociception | 0.93598011 |
| 60 | MP0005171_absent_coat_pigmentation | 0.93457863 |
| 61 | MP0001958_emphysema | 0.92944103 |
| 62 | MP0003186_abnormal_redox_activity | 0.91730825 |
| 63 | MP0002233_abnormal_nose_morphology | 0.91380040 |
| 64 | MP0000427_abnormal_hair_cycle | 0.87815777 |
| 65 | MP0001286_abnormal_eye_development | 0.87620821 |
| 66 | MP0001485_abnormal_pinna_reflex | 0.87264750 |
| 67 | MP0003942_abnormal_urinary_system | 0.86358364 |
| 68 | MP0002210_abnormal_sex_determination | 0.86225067 |
| 69 | MP0001963_abnormal_hearing_physiology | 0.82358134 |
| 70 | MP0006276_abnormal_autonomic_nervous | 0.80690753 |
| 71 | MP0000955_abnormal_spinal_cord | 0.77124261 |
| 72 | MP0003936_abnormal_reproductive_system | 0.77057621 |
| 73 | MP0003121_genomic_imprinting | 0.76262871 |
| 74 | MP0002184_abnormal_innervation | 0.75566804 |
| 75 | MP0002295_abnormal_pulmonary_circulatio | 0.74613782 |
| 76 | MP0005423_abnormal_somatic_nervous | 0.74321416 |
| 77 | MP0009745_abnormal_behavioral_response | 0.73500352 |
| 78 | MP0003567_abnormal_fetal_cardiomyocyte | 0.73202447 |
| 79 | MP0001986_abnormal_taste_sensitivity | 0.71971249 |
| 80 | MP0005084_abnormal_gallbladder_morpholo | 0.71684880 |
| 81 | MP0000462_abnormal_digestive_system | 0.71305934 |
| 82 | MP0003252_abnormal_bile_duct | 0.70779675 |
| 83 | MP0000613_abnormal_salivary_gland | 0.70438026 |
| 84 | MP0001905_abnormal_dopamine_level | 0.67824472 |
| 85 | MP0003115_abnormal_respiratory_system | 0.67788063 |
| 86 | MP0000747_muscle_weakness | 0.67208619 |
| 87 | MP0004742_abnormal_vestibular_system | 0.64563183 |
| 88 | MP0000653_abnormal_sex_gland | 0.64086273 |
| 89 | MP0001145_abnormal_male_reproductive | 0.63376386 |
| 90 | MP0002752_abnormal_somatic_nervous | 0.62994623 |
| 91 | MP0002067_abnormal_sensory_capabilities | 0.62196202 |
| 92 | MP0001486_abnormal_startle_reflex | 0.62132291 |
| 93 | MP0001529_abnormal_vocalization | 0.61552221 |
| 94 | MP0002733_abnormal_thermal_nociception | 0.61371039 |
| 95 | MP0002876_abnormal_thyroid_physiology | 0.61320946 |
| 96 | MP0003283_abnormal_digestive_organ | 0.61072076 |
| 97 | MP0005551_abnormal_eye_electrophysiolog | 0.60906874 |
| 98 | MP0002272_abnormal_nervous_system | 0.59967635 |
| 99 | MP0002697_abnormal_eye_size | 0.58341199 |
| 100 | MP0002109_abnormal_limb_morphology | 0.58010780 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Partial duplication of thumb phalanx (HP:0009944) | 5.60504932 |
| 2 | Aplasia involving bones of the extremities (HP:0009825) | 5.09719546 |
| 3 | Aplasia involving bones of the upper limbs (HP:0009823) | 5.09719546 |
| 4 | Aplasia of the phalanges of the hand (HP:0009802) | 5.09719546 |
| 5 | Partial duplication of the phalanx of hand (HP:0009999) | 5.02486641 |
| 6 | Abnormality of the middle phalanges of the toes (HP:0010183) | 4.67884847 |
| 7 | Esophageal atresia (HP:0002032) | 4.45779189 |
| 8 | Abnormality of the parietal bone (HP:0002696) | 4.41918028 |
| 9 | Aplasia/Hypoplasia of the phalanges of the thumb (HP:0009658) | 4.13479756 |
| 10 | Coronal craniosynostosis (HP:0004440) | 3.98827644 |
| 11 | Stenosis of the external auditory canal (HP:0000402) | 3.95018206 |
| 12 | Megalencephaly (HP:0001355) | 3.94367809 |
| 13 | Neonatal short-limb short stature (HP:0008921) | 3.59318768 |
| 14 | Abnormality of the labia minora (HP:0012880) | 3.58625002 |
| 15 | Septo-optic dysplasia (HP:0100842) | 3.42756311 |
| 16 | Gastrointestinal atresia (HP:0002589) | 3.41726309 |
| 17 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 3.30172271 |
| 18 | Broad distal phalanx of finger (HP:0009836) | 3.21958147 |
| 19 | Abnormality of the 4th metacarpal (HP:0010012) | 3.21515227 |
| 20 | Duplication of thumb phalanx (HP:0009942) | 3.19390537 |
| 21 | Abnormality of incisor morphology (HP:0011063) | 3.15337382 |
| 22 | Nasolacrimal duct obstruction (HP:0000579) | 3.03042337 |
| 23 | Recurrent corneal erosions (HP:0000495) | 3.02110549 |
| 24 | Bronchomalacia (HP:0002780) | 3.00890433 |
| 25 | Down-sloping shoulders (HP:0200021) | 2.99311109 |
| 26 | Absent septum pellucidum (HP:0001331) | 2.97252325 |
| 27 | Conical tooth (HP:0000698) | 2.91683600 |
| 28 | Short 4th metacarpal (HP:0010044) | 2.85484570 |
| 29 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 2.85484570 |
| 30 | Chronic otitis media (HP:0000389) | 2.84226279 |
| 31 | Supernumerary ribs (HP:0005815) | 2.83165172 |
| 32 | Abnormality of the distal phalanx of the thumb (HP:0009617) | 2.79601268 |
| 33 | Supernumerary bones of the axial skeleton (HP:0009144) | 2.71903371 |
| 34 | Alacrima (HP:0000522) | 2.68095608 |
| 35 | Abnormality of the 2nd finger (HP:0004100) | 2.65350805 |
| 36 | Abnormality of the lacrimal duct (HP:0011481) | 2.63022263 |
| 37 | Maternal diabetes (HP:0009800) | 2.59841968 |
| 38 | 3-Methylglutaconic aciduria (HP:0003535) | 2.55103118 |
| 39 | Broad metatarsal (HP:0001783) | 2.51573136 |
| 40 | Split foot (HP:0001839) | 2.49512051 |
| 41 | Aqueductal stenosis (HP:0002410) | 2.48276608 |
| 42 | Abnormality of permanent molar morphology (HP:0011071) | 2.41260866 |
| 43 | Abnormality of the dental root (HP:0006486) | 2.41260866 |
| 44 | Taurodontia (HP:0000679) | 2.41260866 |
| 45 | Thickened helices (HP:0000391) | 2.41215321 |
| 46 | Abnormality of the septum pellucidum (HP:0007375) | 2.40374213 |
| 47 | Bifid scrotum (HP:0000048) | 2.38720133 |
| 48 | Hypoplasia of the radius (HP:0002984) | 2.35950702 |
| 49 | Reticulocytopenia (HP:0001896) | 2.35193435 |
| 50 | Abnormality of alanine metabolism (HP:0010916) | 2.34064702 |
| 51 | Hyperalaninemia (HP:0003348) | 2.34064702 |
| 52 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.34064702 |
| 53 | Visceral angiomatosis (HP:0100761) | 2.31544396 |
| 54 | Humeroradial synostosis (HP:0003041) | 2.29107722 |
| 55 | Synostosis involving the elbow (HP:0003938) | 2.29107722 |
| 56 | Abnormality of the incisor (HP:0000676) | 2.28668015 |
| 57 | Respiratory distress (HP:0002098) | 2.27478325 |
| 58 | Synostosis of carpal bones (HP:0005048) | 2.27457986 |
| 59 | Symphalangism affecting the phalanges of the hand (HP:0009773) | 2.26626039 |
| 60 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.26181342 |
| 61 | Mixed hearing impairment (HP:0000410) | 2.25961885 |
| 62 | Sleep apnea (HP:0010535) | 2.25636149 |
| 63 | Hypoplasia of the ulna (HP:0003022) | 2.25522230 |
| 64 | Abnormality of molar morphology (HP:0011070) | 2.25305337 |
| 65 | Abnormality of molar (HP:0011077) | 2.25305337 |
| 66 | Preaxial foot polydactyly (HP:0001841) | 2.23266068 |
| 67 | Vertebral fusion (HP:0002948) | 2.21964976 |
| 68 | Abnormality of the nasolacrimal system (HP:0000614) | 2.20861915 |
| 69 | Abnormal number of erythroid precursors (HP:0012131) | 2.20637642 |
| 70 | Abnormality of the dental pulp (HP:0006479) | 2.18104684 |
| 71 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.17215294 |
| 72 | Absent radius (HP:0003974) | 2.16228092 |
| 73 | Cutaneous finger syndactyly (HP:0010554) | 2.13792518 |
| 74 | Absent forearm bone (HP:0003953) | 2.12174031 |
| 75 | Aplasia involving forearm bones (HP:0009822) | 2.12174031 |
| 76 | True hermaphroditism (HP:0010459) | 2.10122184 |
| 77 | Acute necrotizing encephalopathy (HP:0006965) | 2.09363947 |
| 78 | Macrocytic anemia (HP:0001972) | 2.08742429 |
| 79 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.08295543 |
| 80 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.08295543 |
| 81 | Neoplasm of the heart (HP:0100544) | 2.06051487 |
| 82 | Hemangiomatosis (HP:0007461) | 2.04736432 |
| 83 | Rib fusion (HP:0000902) | 2.04484275 |
| 84 | Decreased lacrimation (HP:0000633) | 2.03162534 |
| 85 | Hemivertebrae (HP:0002937) | 2.02326205 |
| 86 | Constricted visual fields (HP:0001133) | 1.92895736 |
| 87 | Short phalanx of the thumb (HP:0009660) | 1.92778618 |
| 88 | Increased serum pyruvate (HP:0003542) | 1.91951488 |
| 89 | Vaginal atresia (HP:0000148) | 1.91253683 |
| 90 | Broad hallux (HP:0010055) | 1.88798043 |
| 91 | Hamartoma (HP:0010566) | 1.84980795 |
| 92 | Aplasia/Hypoplasia of the ulna (HP:0006495) | 1.84511536 |
| 93 | Short middle phalanx of finger (HP:0005819) | 1.83906793 |
| 94 | Abnormality of the salivary glands (HP:0010286) | 1.83380132 |
| 95 | 11 pairs of ribs (HP:0000878) | 1.83208374 |
| 96 | Birth length less than 3rd percentile (HP:0003561) | 1.82865588 |
| 97 | Xerostomia (HP:0000217) | 1.82691190 |
| 98 | Abnormal mitochondria in muscle tissue (HP:0008316) | 1.82606683 |
| 99 | Genital tract atresia (HP:0001827) | 1.81408666 |
| 100 | 2-3 toe syndactyly (HP:0004691) | 1.80624061 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | FGFR2 | 6.22872346 |
| 2 | PINK1 | 4.97026355 |
| 3 | WNK4 | 4.47746552 |
| 4 | STK39 | 3.02659728 |
| 5 | CASK | 2.55037885 |
| 6 | MAP2K3 | 2.32762087 |
| 7 | NME2 | 2.13727117 |
| 8 | PNCK | 2.04833057 |
| 9 | FGFR1 | 2.02840580 |
| 10 | NME1 | 1.88512887 |
| 11 | NTRK2 | 1.78668741 |
| 12 | BUB1 | 1.77691504 |
| 13 | MAP3K6 | 1.72882286 |
| 14 | FGFR3 | 1.70829413 |
| 15 | NUAK1 | 1.69086505 |
| 16 | DYRK2 | 1.65442740 |
| 17 | OXSR1 | 1.62843379 |
| 18 | TLK1 | 1.60665098 |
| 19 | ADRBK2 | 1.43157390 |
| 20 | WNK3 | 1.36265323 |
| 21 | PHKG1 | 1.35823895 |
| 22 | PHKG2 | 1.35823895 |
| 23 | LATS1 | 1.35000704 |
| 24 | STK38L | 1.32484014 |
| 25 | PIK3CA | 1.31353675 |
| 26 | PDK2 | 1.29555065 |
| 27 | WNK1 | 1.27542481 |
| 28 | ADRBK1 | 1.18450856 |
| 29 | STK16 | 1.18398607 |
| 30 | MAP2K7 | 1.14877668 |
| 31 | GRK7 | 1.11089718 |
| 32 | ACVR1B | 1.10795929 |
| 33 | GRK1 | 1.08472682 |
| 34 | ABL2 | 1.06826560 |
| 35 | CDK19 | 1.03876532 |
| 36 | TIE1 | 1.03700796 |
| 37 | EPHB2 | 1.02120578 |
| 38 | HIPK2 | 1.01602992 |
| 39 | EPHA4 | 1.00901983 |
| 40 | MAP2K6 | 0.97913286 |
| 41 | DYRK3 | 0.96136949 |
| 42 | OBSCN | 0.94620862 |
| 43 | FRK | 0.93678219 |
| 44 | BMPR1B | 0.93163349 |
| 45 | MINK1 | 0.90826783 |
| 46 | MAP2K4 | 0.87488396 |
| 47 | BCKDK | 0.85813573 |
| 48 | AURKA | 0.78526362 |
| 49 | VRK2 | 0.76075769 |
| 50 | MAP4K2 | 0.73812685 |
| 51 | DYRK1B | 0.69775783 |
| 52 | WEE1 | 0.68761393 |
| 53 | MAP3K3 | 0.66636790 |
| 54 | INSRR | 0.62062033 |
| 55 | TYRO3 | 0.60910533 |
| 56 | PRKCG | 0.58611386 |
| 57 | MAP3K11 | 0.56820770 |
| 58 | TESK2 | 0.53132488 |
| 59 | ZAK | 0.52994234 |
| 60 | CSNK1G3 | 0.51351508 |
| 61 | STK38 | 0.49801259 |
| 62 | MAPK13 | 0.48225149 |
| 63 | PLK1 | 0.47614898 |
| 64 | PLK2 | 0.47035174 |
| 65 | CSNK1G2 | 0.45784444 |
| 66 | PRKACA | 0.43975195 |
| 67 | PIM1 | 0.43361402 |
| 68 | TNIK | 0.42431464 |
| 69 | CSNK2A1 | 0.41996846 |
| 70 | CDK3 | 0.41039901 |
| 71 | VRK1 | 0.40201820 |
| 72 | PRKCE | 0.40105397 |
| 73 | TAOK3 | 0.39732357 |
| 74 | CSNK1G1 | 0.39231433 |
| 75 | CSNK1E | 0.39118325 |
| 76 | AKT2 | 0.37977022 |
| 77 | CSNK2A2 | 0.37709235 |
| 78 | IKBKB | 0.37507647 |
| 79 | MAP3K5 | 0.37208902 |
| 80 | CAMK1 | 0.35368669 |
| 81 | MAP3K7 | 0.35326906 |
| 82 | CSNK1A1L | 0.34824567 |
| 83 | UHMK1 | 0.34624316 |
| 84 | CAMK1G | 0.33513523 |
| 85 | CDK5 | 0.31074452 |
| 86 | MST4 | 0.31039416 |
| 87 | RPS6KA5 | 0.29881009 |
| 88 | MAP3K4 | 0.28621255 |
| 89 | SGK494 | 0.28591741 |
| 90 | SGK223 | 0.28591741 |
| 91 | GRK5 | 0.28327865 |
| 92 | RPS6KA6 | 0.27578080 |
| 93 | CDK9 | 0.26546266 |
| 94 | ERBB2 | 0.26387509 |
| 95 | PASK | 0.24908411 |
| 96 | PRKD3 | 0.24769042 |
| 97 | FGR | 0.24658109 |
| 98 | SGK1 | 0.24565537 |
| 99 | CAMK2A | 0.24175109 |
| 100 | JAK3 | 0.23535156 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 6.00258449 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 4.55114747 |
| 3 | Parkinsons disease_Homo sapiens_hsa05012 | 3.81245318 |
| 4 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.90209567 |
| 5 | Huntingtons disease_Homo sapiens_hsa05016 | 2.75656472 |
| 6 | Alzheimers disease_Homo sapiens_hsa05010 | 2.65771814 |
| 7 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 2.44615995 |
| 8 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.41158232 |
| 9 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.29835440 |
| 10 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.01120908 |
| 11 | Proteasome_Homo sapiens_hsa03050 | 1.87239719 |
| 12 | Asthma_Homo sapiens_hsa05310 | 1.75224343 |
| 13 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.68098892 |
| 14 | Homologous recombination_Homo sapiens_hsa03440 | 1.64927057 |
| 15 | Protein export_Homo sapiens_hsa03060 | 1.60272280 |
| 16 | Nicotine addiction_Homo sapiens_hsa05033 | 1.55368486 |
| 17 | RNA polymerase_Homo sapiens_hsa03020 | 1.50942811 |
| 18 | Sulfur relay system_Homo sapiens_hsa04122 | 1.48468145 |
| 19 | Olfactory transduction_Homo sapiens_hsa04740 | 1.46454184 |
| 20 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.45825208 |
| 21 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 1.37639792 |
| 22 | Spliceosome_Homo sapiens_hsa03040 | 1.36350019 |
| 23 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.34229488 |
| 24 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.33874387 |
| 25 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.29403527 |
| 26 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.26160544 |
| 27 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.23300966 |
| 28 | Basal cell carcinoma_Homo sapiens_hsa05217 | 1.21162286 |
| 29 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.20945858 |
| 30 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.20132312 |
| 31 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.20007018 |
| 32 | DNA replication_Homo sapiens_hsa03030 | 1.15184611 |
| 33 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 1.14577612 |
| 34 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.11503037 |
| 35 | RNA degradation_Homo sapiens_hsa03018 | 1.08606600 |
| 36 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.08062330 |
| 37 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 1.07357561 |
| 38 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.01269701 |
| 39 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.97859558 |
| 40 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.97180968 |
| 41 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.96080927 |
| 42 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.95153140 |
| 43 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.94530571 |
| 44 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.91387462 |
| 45 | Morphine addiction_Homo sapiens_hsa05032 | 0.90447107 |
| 46 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.90301345 |
| 47 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.88297914 |
| 48 | Allograft rejection_Homo sapiens_hsa05330 | 0.87781650 |
| 49 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.87766763 |
| 50 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.86936613 |
| 51 | RNA transport_Homo sapiens_hsa03013 | 0.84773176 |
| 52 | Taste transduction_Homo sapiens_hsa04742 | 0.84310722 |
| 53 | Purine metabolism_Homo sapiens_hsa00230 | 0.83365856 |
| 54 | Basal transcription factors_Homo sapiens_hsa03022 | 0.81101942 |
| 55 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.80474518 |
| 56 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.79583518 |
| 57 | GABAergic synapse_Homo sapiens_hsa04727 | 0.78575929 |
| 58 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.75622110 |
| 59 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.74745519 |
| 60 | Metabolic pathways_Homo sapiens_hsa01100 | 0.72450563 |
| 61 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.66283495 |
| 62 | Peroxisome_Homo sapiens_hsa04146 | 0.65864144 |
| 63 | Retinol metabolism_Homo sapiens_hsa00830 | 0.64904503 |
| 64 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.62384349 |
| 65 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.61924904 |
| 66 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.61084044 |
| 67 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.60956455 |
| 68 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.59850410 |
| 69 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.59307676 |
| 70 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.59201689 |
| 71 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.55935341 |
| 72 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.52834295 |
| 73 | Phototransduction_Homo sapiens_hsa04744 | 0.51676262 |
| 74 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.51042814 |
| 75 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.49654381 |
| 76 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.48947144 |
| 77 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.47129732 |
| 78 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.46529737 |
| 79 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.44964259 |
| 80 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.44055832 |
| 81 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.39906881 |
| 82 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.39418155 |
| 83 | Circadian entrainment_Homo sapiens_hsa04713 | 0.39138213 |
| 84 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.36962333 |
| 85 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.36121634 |
| 86 | Mineral absorption_Homo sapiens_hsa04978 | 0.34907897 |
| 87 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.33496855 |
| 88 | Mismatch repair_Homo sapiens_hsa03430 | 0.33495811 |
| 89 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.33403950 |
| 90 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.30863350 |
| 91 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.30860892 |
| 92 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.30176058 |
| 93 | Alcoholism_Homo sapiens_hsa05034 | 0.29959131 |
| 94 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.29818401 |
| 95 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.25941827 |
| 96 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.23753218 |
| 97 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.23741986 |
| 98 | Insulin secretion_Homo sapiens_hsa04911 | 0.22852576 |
| 99 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.18292908 |
| 100 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.18115937 |

