Rank | Gene Set | Z-score |
---|---|---|
1 | Golgi transport vesicle coating (GO:0048200) | 4.22911755 |
2 | COPI coating of Golgi vesicle (GO:0048205) | 4.22911755 |
3 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 3.95944029 |
4 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 3.95944029 |
5 | hypotonic response (GO:0006971) | 3.92538792 |
6 | nuclear pore complex assembly (GO:0051292) | 3.75927286 |
7 | barbed-end actin filament capping (GO:0051016) | 3.62487506 |
8 | desmosome organization (GO:0002934) | 3.61189688 |
9 | embryonic process involved in female pregnancy (GO:0060136) | 3.49163044 |
10 | antigen processing and presentation of endogenous antigen (GO:0019883) | 3.45534291 |
11 | iron ion import (GO:0097286) | 3.41922987 |
12 | negative regulation of fatty acid transport (GO:2000192) | 3.39736533 |
13 | nuclear pore organization (GO:0006999) | 3.29316024 |
14 | low-density lipoprotein particle clearance (GO:0034383) | 3.29168064 |
15 | negative regulation of protein localization to plasma membrane (GO:1903077) | 3.23763044 |
16 | regulation of cholesterol homeostasis (GO:2000188) | 3.20669560 |
17 | apoptotic cell clearance (GO:0043277) | 3.19179525 |
18 | growth hormone receptor signaling pathway (GO:0060396) | 3.17641704 |
19 | cell adhesion mediated by integrin (GO:0033627) | 3.16619241 |
20 | positive regulation of histone deacetylation (GO:0031065) | 3.07261286 |
21 | cytoskeletal anchoring at plasma membrane (GO:0007016) | 3.07075867 |
22 | protein localization to endosome (GO:0036010) | 3.05612143 |
23 | glycosphingolipid catabolic process (GO:0046479) | 3.05507185 |
24 | skin morphogenesis (GO:0043589) | 3.03607173 |
25 | hemidesmosome assembly (GO:0031581) | 3.03441421 |
26 | response to laminar fluid shear stress (GO:0034616) | 2.98189878 |
27 | activation of signaling protein activity involved in unfolded protein response (GO:0006987) | 2.81704059 |
28 | glycolipid catabolic process (GO:0019377) | 2.80757857 |
29 | regulation of vascular endothelial growth factor signaling pathway (GO:1900746) | 2.79116234 |
30 | cellular response to growth hormone stimulus (GO:0071378) | 2.78746355 |
31 | regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547) | 2.78425806 |
32 | pore complex assembly (GO:0046931) | 2.78361744 |
33 | maintenance of protein localization in endoplasmic reticulum (GO:0035437) | 2.74425468 |
34 | positive regulation of nuclease activity (GO:0032075) | 2.72106661 |
35 | regulation of cholesterol storage (GO:0010885) | 2.70461736 |
36 | peptide catabolic process (GO:0043171) | 2.69444221 |
37 | response to thyroid hormone (GO:0097066) | 2.67827573 |
38 | membrane raft organization (GO:0031579) | 2.64796502 |
39 | positive regulation of membrane protein ectodomain proteolysis (GO:0051044) | 2.64249624 |
40 | cell-substrate junction assembly (GO:0007044) | 2.63964436 |
41 | endodermal cell differentiation (GO:0035987) | 2.62034149 |
42 | JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397) | 2.60431898 |
43 | cellular response to thyroid hormone stimulus (GO:0097067) | 2.58957295 |
44 | hepatocyte apoptotic process (GO:0097284) | 2.55917174 |
45 | endoplasmic reticulum unfolded protein response (GO:0030968) | 2.55859993 |
46 | positive regulation of syncytium formation by plasma membrane fusion (GO:0060143) | 2.55634401 |
47 | membrane protein ectodomain proteolysis (GO:0006509) | 2.54043708 |
48 | protein retention in ER lumen (GO:0006621) | 2.52947771 |
49 | positive regulation of p38MAPK cascade (GO:1900745) | 2.52499121 |
50 | COPII vesicle coating (GO:0048208) | 2.50673220 |
51 | surfactant homeostasis (GO:0043129) | 2.50615848 |
52 | regulation of nuclease activity (GO:0032069) | 2.48441067 |
53 | regulation of gamma-delta T cell differentiation (GO:0045586) | 2.47755015 |
54 | regulation of membrane protein ectodomain proteolysis (GO:0051043) | 2.47628764 |
55 | focal adhesion assembly (GO:0048041) | 2.47053815 |
56 | cell-substrate adherens junction assembly (GO:0007045) | 2.47053815 |
57 | negative regulation of erythrocyte differentiation (GO:0045647) | 2.46862363 |
58 | oligosaccharide catabolic process (GO:0009313) | 2.45685494 |
59 | retrograde vesicle-mediated transport, Golgi to ER (GO:0006890) | 2.45117088 |
60 | positive regulation of Cdc42 GTPase activity (GO:0043089) | 2.43865209 |
61 | regulation of histone H3-K27 methylation (GO:0061085) | 2.43561440 |
62 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 2.43262705 |
63 | bundle of His cell to Purkinje myocyte communication (GO:0086069) | 2.42835376 |
64 | negative regulation of anoikis (GO:2000811) | 2.42747339 |
65 | regulation of interleukin-12 biosynthetic process (GO:0045075) | 2.42627784 |
66 | cellular response to unfolded protein (GO:0034620) | 2.41285731 |
67 | positive regulation of receptor recycling (GO:0001921) | 2.41034772 |
68 | negative regulation of lipid transport (GO:0032369) | 2.40456743 |
69 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 2.40073291 |
70 | positive regulation of natural killer cell differentiation (GO:0032825) | 2.39658451 |
71 | negative regulation of establishment of protein localization to plasma membrane (GO:0090005) | 2.39468656 |
72 | positive regulation of interferon-alpha production (GO:0032727) | 2.38813103 |
73 | 4-hydroxyproline metabolic process (GO:0019471) | 2.37050126 |
74 | regulation of protein heterodimerization activity (GO:0043497) | 2.36882373 |
75 | positive regulation of cellular amide metabolic process (GO:0034250) | 2.34766254 |
76 | regulation of protein localization to plasma membrane (GO:1903076) | 2.34357378 |
77 | pentose-phosphate shunt (GO:0006098) | 2.34343487 |
78 | ER-nucleus signaling pathway (GO:0006984) | 2.33981669 |
79 | gland morphogenesis (GO:0022612) | 2.33658435 |
80 | maternal placenta development (GO:0001893) | 2.31748226 |
81 | ceramide catabolic process (GO:0046514) | 2.31621502 |
82 | regulation of nucleobase-containing compound transport (GO:0032239) | 2.31081582 |
83 | positive regulation of endothelial cell apoptotic process (GO:2000353) | 2.29607675 |
84 | antigen processing and presentation via MHC class Ib (GO:0002475) | 2.29540030 |
85 | alpha-linolenic acid metabolic process (GO:0036109) | 2.28815797 |
86 | regulation of interferon-alpha production (GO:0032647) | 2.28489795 |
87 | response to peptidoglycan (GO:0032494) | 2.26849649 |
88 | regulation of RNA export from nucleus (GO:0046831) | 2.26743102 |
89 | positive regulation of gamma-delta T cell activation (GO:0046645) | 2.26367839 |
90 | protein hydroxylation (GO:0018126) | 2.26247280 |
91 | basement membrane organization (GO:0071711) | 2.25742224 |
92 | activation of Rac GTPase activity (GO:0032863) | 2.24662172 |
93 | regulation of transforming growth factor beta1 production (GO:0032908) | 2.23611919 |
94 | hyaluronan catabolic process (GO:0030214) | 2.23401756 |
95 | mammary gland epithelial cell proliferation (GO:0033598) | 2.23167151 |
96 | proline biosynthetic process (GO:0006561) | 2.22496026 |
97 | cortical actin cytoskeleton organization (GO:0030866) | 2.21689747 |
98 | peptidyl-glutamic acid carboxylation (GO:0017187) | 2.21561257 |
99 | protein carboxylation (GO:0018214) | 2.21561257 |
100 | establishment of endothelial barrier (GO:0061028) | 2.20807356 |
101 | negative regulation of fibrinolysis (GO:0051918) | 2.20054966 |
102 | epithelial cell differentiation involved in prostate gland development (GO:0060742) | 2.19998203 |
103 | negative regulation of epidermal growth factor-activated receptor activity (GO:0007175) | 2.19659868 |
104 | positive regulation of extracellular matrix organization (GO:1903055) | 2.19122142 |
105 | positive regulation of leukocyte degranulation (GO:0043302) | 2.19035553 |
106 | lipopolysaccharide-mediated signaling pathway (GO:0031663) | 2.18971295 |
107 | cellular response to topologically incorrect protein (GO:0035967) | 2.18834100 |
108 | regulation of water loss via skin (GO:0033561) | 2.18188577 |
109 | fibril organization (GO:0097435) | 2.18118085 |
110 | positive regulation of protein deacetylation (GO:0090312) | 2.18054480 |
111 | regulation of extracellular matrix disassembly (GO:0010715) | 2.18019612 |
112 | mannose metabolic process (GO:0006013) | 2.17822735 |
113 | mesodermal cell differentiation (GO:0048333) | 2.17781789 |
114 | regulation of fatty acid beta-oxidation (GO:0031998) | 2.17645220 |
115 | epithelial cell-cell adhesion (GO:0090136) | 2.17111932 |
116 | adhesion of symbiont to host (GO:0044406) | 2.16857788 |
117 | positive regulation of lamellipodium assembly (GO:0010592) | 2.16538039 |
118 | regulation of anoikis (GO:2000209) | 2.14912854 |
119 | substrate adhesion-dependent cell spreading (GO:0034446) | 2.14684293 |
120 | cellular response to vitamin (GO:0071295) | 2.14319043 |
121 | regulation of leukocyte degranulation (GO:0043300) | 2.14100480 |
122 | localization within membrane (GO:0051668) | 2.13738559 |
123 | dichotomous subdivision of an epithelial terminal unit (GO:0060600) | 2.13061128 |
124 | regulation of necrotic cell death (GO:0010939) | 2.12822515 |
125 | positive regulation of bone resorption (GO:0045780) | 2.12722033 |
126 | positive regulation of bone remodeling (GO:0046852) | 2.12722033 |
127 | positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:00360 | 2.12629978 |
128 | wound healing, spreading of epidermal cells (GO:0035313) | 2.12188484 |
129 | positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr | 2.12020172 |
130 | cellular copper ion homeostasis (GO:0006878) | 2.11981097 |
131 | positive regulation of fatty acid beta-oxidation (GO:0032000) | 2.11335096 |
132 | negative regulation of toll-like receptor 4 signaling pathway (GO:0034144) | 2.11263144 |
133 | regulation of interferon-beta biosynthetic process (GO:0045357) | 2.11037159 |
134 | integrin-mediated signaling pathway (GO:0007229) | 2.10812525 |
135 | peptidyl-proline hydroxylation (GO:0019511) | 2.10782111 |
136 | cellular response to vitamin D (GO:0071305) | 2.10622983 |
137 | intestinal cholesterol absorption (GO:0030299) | 2.10562159 |
138 | vascular endothelial growth factor signaling pathway (GO:0038084) | 2.09760292 |
139 | regulation of early endosome to late endosome transport (GO:2000641) | 2.09460994 |
140 | response to fluid shear stress (GO:0034405) | 2.09111323 |
141 | NADPH regeneration (GO:0006740) | 2.08586731 |
142 | regulation of gamma-delta T cell activation (GO:0046643) | 2.08150608 |
143 | pinocytosis (GO:0006907) | 2.07998880 |
144 | receptor catabolic process (GO:0032801) | 2.07880910 |
145 | germ cell migration (GO:0008354) | 2.07345220 |
146 | regulation of necroptotic process (GO:0060544) | 2.07129064 |
147 | plasma lipoprotein particle clearance (GO:0034381) | 2.06965983 |
148 | stress fiber assembly (GO:0043149) | 2.06959016 |
149 | positive regulation of blood vessel endothelial cell migration (GO:0043536) | 2.06838792 |
150 | virion attachment to host cell (GO:0019062) | 2.06353505 |
151 | adhesion of symbiont to host cell (GO:0044650) | 2.06353505 |
152 | vesicle coating (GO:0006901) | 2.06200406 |
153 | regulation of vitamin metabolic process (GO:0030656) | 2.04815869 |
154 | definitive hemopoiesis (GO:0060216) | 2.04086177 |
155 | positive regulation of triglyceride biosynthetic process (GO:0010867) | 2.02707547 |
156 | regulation of glucose import in response to insulin stimulus (GO:2001273) | 2.01384530 |
157 | response to muramyl dipeptide (GO:0032495) | 2.00741755 |
158 | response to growth hormone (GO:0060416) | 2.00232691 |
159 | sequestering of metal ion (GO:0051238) | 1.99809435 |
160 | adherens junction assembly (GO:0034333) | 1.99537981 |
161 | response to endoplasmic reticulum stress (GO:0034976) | 1.98634130 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 4.62028115 |
2 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 3.68919349 |
3 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 3.22802182 |
4 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 3.21433545 |
5 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 2.72978272 |
6 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.53460213 |
7 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 2.49376990 |
8 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 2.48623177 |
9 | * CLOCK_20551151_ChIP-Seq_293T_Human | 2.45488168 |
10 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 2.44552767 |
11 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 2.44506116 |
12 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 2.36530170 |
13 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 2.30542001 |
14 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 2.30309064 |
15 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 2.28454105 |
16 | MYC_22102868_ChIP-Seq_BL_Human | 2.15493597 |
17 | LXR_22158963_ChIP-Seq_LIVER_Mouse | 2.11756953 |
18 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 2.04217740 |
19 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.96812467 |
20 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.96162830 |
21 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.93124134 |
22 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.91030926 |
23 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.89869607 |
24 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.85248153 |
25 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.79461415 |
26 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.77872969 |
27 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.77325891 |
28 | MAF_26560356_Chip-Seq_TH1_Human | 1.70772544 |
29 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.70611362 |
30 | * MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 1.69904096 |
31 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 1.68611506 |
32 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.66852146 |
33 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 1.65677094 |
34 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.65599945 |
35 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 1.64976178 |
36 | E2F7_22180533_ChIP-Seq_HELA_Human | 1.63362593 |
37 | SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 1.63254006 |
38 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.61562243 |
39 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.61312188 |
40 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.61014534 |
41 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.59114172 |
42 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.58785400 |
43 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.58681699 |
44 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 1.57363979 |
45 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.57136754 |
46 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 1.54173586 |
47 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.54133423 |
48 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 1.52738260 |
49 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.51865454 |
50 | UTX_26944678_Chip-Seq_JUKART_Human | 1.50667816 |
51 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 1.50327953 |
52 | ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.49476605 |
53 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 1.49031780 |
54 | SOX2_27498859_Chip-Seq_STOMACH_Mouse | 1.47112612 |
55 | MYB_26560356_Chip-Seq_TH2_Human | 1.47020587 |
56 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 1.46667747 |
57 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.46221254 |
58 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.46088751 |
59 | ATF3_27146783_Chip-Seq_COLON_Human | 1.44993454 |
60 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 1.40497615 |
61 | P300_27058665_Chip-Seq_ZR-75-30cells_Human | 1.40348234 |
62 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.38261333 |
63 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.37925165 |
64 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 1.37028859 |
65 | SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 1.36489332 |
66 | SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 1.36489332 |
67 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.36261279 |
68 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.35572700 |
69 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.33798116 |
70 | * TFEB_21752829_ChIP-Seq_HELA_Human | 1.33313335 |
71 | * TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.32899755 |
72 | GATA6_25053715_ChIP-Seq_YYC3_Human | 1.30415473 |
73 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.29951934 |
74 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.29323073 |
75 | MYB_26560356_Chip-Seq_TH1_Human | 1.29146980 |
76 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 1.26588143 |
77 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.23775738 |
78 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.23382151 |
79 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.20586015 |
80 | FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human | 1.19799767 |
81 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 1.19497504 |
82 | * GATA1_19941826_ChIP-Seq_K562_Human | 1.19451748 |
83 | * RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.19446409 |
84 | EOMES_20176728_ChIP-ChIP_TSCs_Mouse | 1.19351521 |
85 | FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.18025152 |
86 | SPI1_23127762_ChIP-Seq_K562_Human | 1.15906068 |
87 | GATA4_25053715_ChIP-Seq_YYC3_Human | 1.14920382 |
88 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 1.14621491 |
89 | * NCOR1_26117541_ChIP-Seq_K562_Human | 1.14345460 |
90 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.14105325 |
91 | * WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 1.13896385 |
92 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.13139925 |
93 | SOX2_20726797_ChIP-Seq_SW620_Human | 1.12998488 |
94 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.12888179 |
95 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.12371475 |
96 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.11983268 |
97 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.10117421 |
98 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.09384988 |
99 | * BRD4_25478319_ChIP-Seq_HGPS_Human | 1.09001621 |
100 | * CHD1_26751641_Chip-Seq_LNCaP_Human | 1.08310723 |
101 | P63_26484246_Chip-Seq_KERATINOCYTES_Human | 1.08033606 |
102 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.07852873 |
103 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.07661371 |
104 | TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 1.07050266 |
105 | * UBF1/2_26484160_Chip-Seq_HMECs_Human | 1.05997019 |
106 | NKX2-5_21415370_ChIP-Seq_HL-1_Mouse | 1.05862989 |
107 | SOX9_24532713_ChIP-Seq_HFSC_Mouse | 1.05516142 |
108 | CDX2_20551321_ChIP-Seq_CACO-2_Human | 1.05014161 |
109 | * GATA2_19941826_ChIP-Seq_K562_Human | 1.03586884 |
110 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 1.03268413 |
111 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.02545504 |
112 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.02124246 |
113 | RUNX1_27514584_Chip-Seq_MCF-7_Human | 1.01606249 |
114 | TBX20_22328084_ChIP-Seq_HEART_Mouse | 1.01315727 |
115 | TBX20_22080862_ChIP-Seq_HEART_Mouse | 1.01315727 |
116 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.00625743 |
117 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 0.99590908 |
118 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 0.98818826 |
119 | JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.98735815 |
120 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 0.98626474 |
121 | GATA1_22025678_ChIP-Seq_K562_Human | 0.98466195 |
122 | NFIB_24661679_ChIP-Seq_LUNG_Mouse | 0.98459994 |
123 | SALL4_18804426_ChIP-ChIP_XEN_Mouse | 0.98415566 |
124 | PU_27001747_Chip-Seq_BMDM_Mouse | 0.98000416 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003705_abnormal_hypodermis_morpholog | 3.37920396 |
2 | MP0003300_gastrointestinal_ulcer | 3.24924254 |
3 | MP0008438_abnormal_cutaneous_collagen | 2.68389854 |
4 | MP0010352_gastrointestinal_tract_polyps | 2.41423947 |
5 | MP0003566_abnormal_cell_adhesion | 2.32496104 |
6 | MP0009840_abnormal_foam_cell | 2.07442067 |
7 | MP0006054_spinal_hemorrhage | 1.97644995 |
8 | MP0005360_urolithiasis | 1.95969778 |
9 | MP0005275_abnormal_skin_tensile | 1.93129355 |
10 | MP0010234_abnormal_vibrissa_follicle | 1.90921113 |
11 | MP0005451_abnormal_body_composition | 1.90141362 |
12 | MP0005023_abnormal_wound_healing | 1.85546099 |
13 | MP0003303_peritoneal_inflammation | 1.84100805 |
14 | MP0002877_abnormal_melanocyte_morpholog | 1.79848643 |
15 | MP0004947_skin_inflammation | 1.79611162 |
16 | MP0003436_decreased_susceptibility_to | 1.71352236 |
17 | MP0002139_abnormal_hepatobiliary_system | 1.70090572 |
18 | MP0005409_darkened_coat_color | 1.68602024 |
19 | MP0005076_abnormal_cell_differentiation | 1.66607946 |
20 | MP0002009_preneoplasia | 1.66586454 |
21 | MP0005058_abnormal_lysosome_morphology | 1.57746117 |
22 | MP0003828_pulmonary_edema | 1.56535849 |
23 | MP0000685_abnormal_immune_system | 1.55995862 |
24 | MP0003656_abnormal_erythrocyte_physiolo | 1.55748864 |
25 | MP0003279_aneurysm | 1.49651086 |
26 | MP0002933_joint_inflammation | 1.46960220 |
27 | MP0008260_abnormal_autophagy | 1.45493896 |
28 | MP0004782_abnormal_surfactant_physiolog | 1.42085112 |
29 | MP0003453_abnormal_keratinocyte_physiol | 1.40429791 |
30 | MP0002166_altered_tumor_susceptibility | 1.40225113 |
31 | MP0005501_abnormal_skin_physiology | 1.39277047 |
32 | MP0009278_abnormal_bone_marrow | 1.37642326 |
33 | MP0003252_abnormal_bile_duct | 1.37352594 |
34 | MP0003091_abnormal_cell_migration | 1.37243738 |
35 | MP0003191_abnormal_cellular_cholesterol | 1.36036879 |
36 | MP0009384_cardiac_valve_regurgitation | 1.34567437 |
37 | MP0003950_abnormal_plasma_membrane | 1.33761761 |
38 | MP0001958_emphysema | 1.33133367 |
39 | MP0001533_abnormal_skeleton_physiology | 1.31387353 |
40 | MP0004272_abnormal_basement_membrane | 1.30132258 |
41 | MP0010155_abnormal_intestine_physiology | 1.28691653 |
42 | MP0004233_abnormal_muscle_weight | 1.28582835 |
43 | MP0002060_abnormal_skin_morphology | 1.27213806 |
44 | MP0001849_ear_inflammation | 1.26507389 |
45 | MP0005083_abnormal_biliary_tract | 1.25931361 |
46 | MP0001790_abnormal_immune_system | 1.25874869 |
47 | MP0005387_immune_system_phenotype | 1.25874869 |
48 | MP0001348_abnormal_lacrimal_gland | 1.23128355 |
49 | MP0005365_abnormal_bile_salt | 1.20791257 |
50 | MP0003045_fibrosis | 1.20014853 |
51 | MP0010368_abnormal_lymphatic_system | 1.19172051 |
52 | MP0003941_abnormal_skin_development | 1.18469904 |
53 | MP0005464_abnormal_platelet_physiology | 1.18460100 |
54 | MP0004185_abnormal_adipocyte_glucose | 1.16172897 |
55 | MP0001666_abnormal_nutrient_absorption | 1.14092421 |
56 | MP0009333_abnormal_splenocyte_physiolog | 1.13450917 |
57 | MP0006082_CNS_inflammation | 1.12767010 |
58 | MP0004264_abnormal_extraembryonic_tissu | 1.12631176 |
59 | MP0002138_abnormal_hepatobiliary_system | 1.07939785 |
60 | MP0005621_abnormal_cell_physiology | 1.06998664 |
61 | MP0000609_abnormal_liver_physiology | 1.06994132 |
62 | MP0001873_stomach_inflammation | 1.06564957 |
63 | MP0001915_intracranial_hemorrhage | 1.06289231 |
64 | MP0002998_abnormal_bone_remodeling | 1.05391177 |
65 | MP0005165_increased_susceptibility_to | 1.04895330 |
66 | MP0000733_abnormal_muscle_development | 1.04638328 |
67 | MP0002419_abnormal_innate_immunity | 1.03696548 |
68 | MP0010678_abnormal_skin_adnexa | 1.03253296 |
69 | MP0000858_altered_metastatic_potential | 1.03138129 |
70 | MP0001835_abnormal_antigen_presentation | 1.01808528 |
71 | MP0003448_altered_tumor_morphology | 1.01119336 |
72 | MP0002168_other_aberrant_phenotype | 1.00978265 |
73 | MP0001243_abnormal_dermal_layer | 0.99719290 |
74 | MP0002405_respiratory_system_inflammati | 0.98481234 |
75 | MP0005000_abnormal_immune_tolerance | 0.98108616 |
76 | MP0003724_increased_susceptibility_to | 0.97308571 |
77 | MP0002254_reproductive_system_inflammat | 0.97212542 |
78 | MP0002452_abnormal_antigen_presenting | 0.97001933 |
79 | MP0005085_abnormal_gallbladder_physiolo | 0.95773468 |
80 | MP0005025_abnormal_response_to | 0.95709830 |
81 | MP0010329_abnormal_lipoprotein_level | 0.95668720 |
82 | MP0009643_abnormal_urine_homeostasis | 0.95411673 |
83 | MP0001800_abnormal_humoral_immune | 0.95186607 |
84 | MP0003221_abnormal_cardiomyocyte_apopto | 0.95123397 |
85 | MP0005257_abnormal_intraocular_pressure | 0.94973050 |
86 | MP0001845_abnormal_inflammatory_respons | 0.94644329 |
87 | MP0000465_gastrointestinal_hemorrhage | 0.94511915 |
88 | MP0005164_abnormal_response_to | 0.94320788 |
89 | MP0009785_altered_susceptibility_to | 0.93488197 |
90 | MP0002896_abnormal_bone_mineralization | 0.92180877 |
91 | MP0002006_tumorigenesis | 0.92028913 |
92 | MP0002796_impaired_skin_barrier | 0.90712080 |
93 | MP0001216_abnormal_epidermal_layer | 0.90308232 |
94 | MP0001853_heart_inflammation | 0.90251064 |
95 | MP0001545_abnormal_hematopoietic_system | 0.90211246 |
96 | MP0005397_hematopoietic_system_phenotyp | 0.90211246 |
97 | MP0003866_abnormal_defecation | 0.88841558 |
98 | MP0000003_abnormal_adipose_tissue | 0.88568188 |
99 | MP0003763_abnormal_thymus_physiology | 0.87001116 |
100 | MP0004808_abnormal_hematopoietic_stem | 0.86257805 |
101 | MP0003172_abnormal_lysosome_physiology | 0.85378494 |
102 | MP0005375_adipose_tissue_phenotype | 0.85024744 |
103 | MP0008875_abnormal_xenobiotic_pharmacok | 0.84987480 |
104 | MP0003795_abnormal_bone_structure | 0.84716721 |
105 | MP0002723_abnormal_immune_serum | 0.84324199 |
106 | MP0010307_abnormal_tumor_latency | 0.83913927 |
107 | MP0000767_abnormal_smooth_muscle | 0.83802719 |
108 | MP0003183_abnormal_peptide_metabolism | 0.82819994 |
109 | MP0001851_eye_inflammation | 0.82783319 |
110 | MP0001730_embryonic_growth_arrest | 0.82278681 |
111 | MP0002086_abnormal_extraembryonic_tissu | 0.82227195 |
112 | MP0000343_altered_response_to | 0.81350175 |
113 | MP0001819_abnormal_immune_cell | 0.80755149 |
114 | MP0002420_abnormal_adaptive_immunity | 0.80612658 |
115 | MP0000598_abnormal_liver_morphology | 0.80190091 |
116 | MP0000377_abnormal_hair_follicle | 0.79821341 |
117 | MP0000490_abnormal_crypts_of | 0.79736456 |
118 | MP0005666_abnormal_adipose_tissue | 0.79561942 |
119 | MP0008004_abnormal_stomach_pH | 0.79413499 |
120 | MP0005390_skeleton_phenotype | 0.78774780 |
121 | MP0004510_myositis | 0.78316161 |
122 | MP0003868_abnormal_feces_composition | 0.77336520 |
123 | MP0005671_abnormal_response_to | 0.76708569 |
124 | MP0002396_abnormal_hematopoietic_system | 0.76430762 |
125 | MP0005623_abnormal_meninges_morphology | 0.75849551 |
126 | MP0005166_decreased_susceptibility_to | 0.74907203 |
127 | MP0003075_altered_response_to | 0.74083785 |
128 | MP0009931_abnormal_skin_appearance | 0.73576281 |
129 | MP0000604_amyloidosis | 0.72373289 |
130 | MP0000681_abnormal_thyroid_gland | 0.72161978 |
131 | MP0004883_abnormal_blood_vessel | 0.71551897 |
132 | MP0003806_abnormal_nucleotide_metabolis | 0.70785088 |
133 | MP0000627_abnormal_mammary_gland | 0.70656518 |
134 | MP0000249_abnormal_blood_vessel | 0.70254653 |
135 | MP0009780_abnormal_chondrocyte_physiolo | 0.69518703 |
136 | MP0005384_cellular_phenotype | 0.68952183 |
137 | MP0002098_abnormal_vibrissa_morphology | 0.68574591 |
138 | MP0003984_embryonic_growth_retardation | 0.68251955 |
139 | MP0001191_abnormal_skin_condition | 0.67326838 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Protrusio acetabuli (HP:0003179) | 3.97744169 |
2 | Premature rupture of membranes (HP:0001788) | 3.40978181 |
3 | Cerebral aneurysm (HP:0004944) | 3.16162240 |
4 | Aortic aneurysm (HP:0004942) | 2.96616280 |
5 | Peritonitis (HP:0002586) | 2.95108004 |
6 | Cervical subluxation (HP:0003308) | 2.85321117 |
7 | Osteolytic defects of the hand bones (HP:0009699) | 2.73813142 |
8 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 2.73813142 |
9 | Atrophic scars (HP:0001075) | 2.72241702 |
10 | Myocardial infarction (HP:0001658) | 2.62731497 |
11 | Aortic dissection (HP:0002647) | 2.60751879 |
12 | Abnormality of liposaccharide metabolism (HP:0010968) | 2.56115548 |
13 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 2.56115548 |
14 | Abnormality of glycolipid metabolism (HP:0010969) | 2.56115548 |
15 | Ankyloglossia (HP:0010296) | 2.54059115 |
16 | Deep venous thrombosis (HP:0002625) | 2.48276849 |
17 | Shallow orbits (HP:0000586) | 2.47911107 |
18 | Mucopolysacchariduria (HP:0008155) | 2.45617503 |
19 | Urinary glycosaminoglycan excretion (HP:0003541) | 2.45617503 |
20 | Spinal cord lesions (HP:0100561) | 2.45370498 |
21 | Syringomyelia (HP:0003396) | 2.45370498 |
22 | Interstitial pulmonary disease (HP:0006530) | 2.45234191 |
23 | Right ventricular cardiomyopathy (HP:0011663) | 2.44996012 |
24 | Eczematoid dermatitis (HP:0000976) | 2.44359835 |
25 | Ankle contracture (HP:0006466) | 2.42847259 |
26 | Xanthomatosis (HP:0000991) | 2.40695914 |
27 | Aneurysm (HP:0002617) | 2.29910610 |
28 | Dysostosis multiplex (HP:0000943) | 2.28337463 |
29 | Mitral valve prolapse (HP:0001634) | 2.26963731 |
30 | Dilatation of the ascending aorta (HP:0005111) | 2.25841881 |
31 | Thin bony cortex (HP:0002753) | 2.25652316 |
32 | Abnormality of polysaccharide metabolism (HP:0011012) | 2.24241339 |
33 | Abnormality of glycosaminoglycan metabolism (HP:0004371) | 2.24241339 |
34 | Abnormality of mucopolysaccharide metabolism (HP:0011020) | 2.24241339 |
35 | Abnormality of oral frenula (HP:0000190) | 2.23811878 |
36 | Flat acetabular roof (HP:0003180) | 2.23063788 |
37 | Esophageal varix (HP:0002040) | 2.22881403 |
38 | Vertebral compression fractures (HP:0002953) | 2.22701272 |
39 | Distal lower limb amyotrophy (HP:0008944) | 2.21619698 |
40 | Increased density of long bones (HP:0006392) | 2.19523949 |
41 | Insidious onset (HP:0003587) | 2.18626173 |
42 | Termporal pattern (HP:0011008) | 2.18626173 |
43 | Ulnar bowing (HP:0003031) | 2.15778128 |
44 | Absent frontal sinuses (HP:0002688) | 2.15551521 |
45 | Increased mean platelet volume (HP:0011877) | 2.14152502 |
46 | Broad metatarsal (HP:0001783) | 2.11467305 |
47 | Increased cerebral lipofuscin (HP:0011813) | 2.09713621 |
48 | Broad face (HP:0000283) | 2.09071143 |
49 | Abnormal platelet volume (HP:0011876) | 2.08182434 |
50 | Fragile skin (HP:0001030) | 2.06498546 |
51 | Distal upper limb amyotrophy (HP:0007149) | 2.06055268 |
52 | Upper limb amyotrophy (HP:0009129) | 2.06055268 |
53 | Vacuolated lymphocytes (HP:0001922) | 2.03543492 |
54 | Hematochezia (HP:0002573) | 2.00884755 |
55 | Blue sclerae (HP:0000592) | 2.00211947 |
56 | Aplasia/Hypoplasia of the frontal sinuses (HP:0009119) | 1.99099548 |
57 | Abnormality of the common coagulation pathway (HP:0010990) | 1.98197835 |
58 | Abnormality of the peritoneum (HP:0002585) | 1.95097485 |
59 | Distal lower limb muscle weakness (HP:0009053) | 1.93880812 |
60 | Persistence of primary teeth (HP:0006335) | 1.91127111 |
61 | Spontaneous hematomas (HP:0007420) | 1.89606388 |
62 | Disproportionate tall stature (HP:0001519) | 1.89586274 |
63 | Centrally nucleated skeletal muscle fibers (HP:0003687) | 1.88839964 |
64 | Mitral stenosis (HP:0001718) | 1.88807385 |
65 | Spondylolisthesis (HP:0003302) | 1.88590296 |
66 | Increased connective tissue (HP:0009025) | 1.87241449 |
67 | Cone-shaped epiphyses of the phalanges of the hand (HP:0010230) | 1.87147088 |
68 | Wormian bones (HP:0002645) | 1.86313803 |
69 | Coarse hair (HP:0002208) | 1.83700497 |
70 | Hand muscle atrophy (HP:0009130) | 1.83686738 |
71 | Abnormality of nail color (HP:0100643) | 1.82425701 |
72 | Vascular tortuosity (HP:0004948) | 1.81763556 |
73 | Spinal rigidity (HP:0003306) | 1.81465123 |
74 | Autoimmune thrombocytopenia (HP:0001973) | 1.81386588 |
75 | Aplasia/Hypoplasia involving the sinuses (HP:0009120) | 1.79220775 |
76 | Abnormality of the acetabulum (HP:0003170) | 1.78811562 |
77 | Arterial tortuosity (HP:0005116) | 1.77937610 |
78 | Pustule (HP:0200039) | 1.77596254 |
79 | Radial bowing (HP:0002986) | 1.77312302 |
80 | Polycythemia (HP:0001901) | 1.77201102 |
81 | Ectopia lentis (HP:0001083) | 1.76832861 |
82 | Bowing of the arm (HP:0006488) | 1.76528113 |
83 | Bowed forearm bones (HP:0003956) | 1.76528113 |
84 | Abnormality of monocarboxylic acid metabolism (HP:0010996) | 1.76324333 |
85 | Subacute progressive viral hepatitis (HP:0006572) | 1.76242743 |
86 | Axonal loss (HP:0003447) | 1.75934121 |
87 | Cardiovascular calcification (HP:0011915) | 1.75734823 |
88 | Abnormality of the distal phalanges of the toes (HP:0010182) | 1.75321173 |
89 | Asymmetry of the thorax (HP:0001555) | 1.74793102 |
90 | Abdominal distention (HP:0003270) | 1.74530187 |
91 | Glucose intolerance (HP:0000833) | 1.73167078 |
92 | Abnormal foot bone ossification (HP:0010675) | 1.72193862 |
93 | Papillary thyroid carcinoma (HP:0002895) | 1.71037844 |
94 | Natal tooth (HP:0000695) | 1.70783533 |
95 | Hypoglycemic coma (HP:0001325) | 1.70704255 |
96 | Focal segmental glomerulosclerosis (HP:0000097) | 1.69935994 |
97 | Hyperacusis (HP:0010780) | 1.69899726 |
98 | Protuberant abdomen (HP:0001538) | 1.69724055 |
99 | Abnormality of glutamine family amino acid metabolism (HP:0010902) | 1.69659354 |
100 | Bone pain (HP:0002653) | 1.69580132 |
101 | Colitis (HP:0002583) | 1.68836945 |
102 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 1.68624036 |
103 | Relative macrocephaly (HP:0004482) | 1.68616917 |
104 | Abnormal platelet function (HP:0011869) | 1.68251549 |
105 | Impaired platelet aggregation (HP:0003540) | 1.68251549 |
106 | Fatigue (HP:0012378) | 1.68178505 |
107 | Cellulitis (HP:0100658) | 1.68046734 |
108 | Milia (HP:0001056) | 1.68003967 |
109 | Genu recurvatum (HP:0002816) | 1.67981475 |
110 | Tetraparesis (HP:0002273) | 1.67851443 |
111 | Thoracolumbar scoliosis (HP:0002944) | 1.67460812 |
112 | Loss of speech (HP:0002371) | 1.67373612 |
113 | Hydroxyprolinuria (HP:0003080) | 1.67210807 |
114 | Abnormality of proline metabolism (HP:0010907) | 1.67210807 |
115 | Back pain (HP:0003418) | 1.67150513 |
116 | Intrahepatic cholestasis (HP:0001406) | 1.66878049 |
117 | Increased IgE level (HP:0003212) | 1.66302636 |
118 | Curly hair (HP:0002212) | 1.65710280 |
119 | Advanced eruption of teeth (HP:0006288) | 1.65661629 |
120 | Cupped ribs (HP:0000887) | 1.65373732 |
121 | Myositis (HP:0100614) | 1.64966021 |
122 | Malnutrition (HP:0004395) | 1.64790855 |
123 | Abnormality of skull ossification (HP:0002703) | 1.64574733 |
124 | Achilles tendon contracture (HP:0001771) | 1.64077794 |
125 | Mildly elevated creatine phosphokinase (HP:0008180) | 1.62851854 |
126 | Gingivitis (HP:0000230) | 1.62468024 |
127 | Complement deficiency (HP:0004431) | 1.61922815 |
128 | Beaking of vertebral bodies (HP:0004568) | 1.61794623 |
129 | Abnormality of the nasal mucosa (HP:0000433) | 1.61509517 |
130 | Short nail (HP:0001799) | 1.61202429 |
131 | Abnormality of the distal phalanx of the thumb (HP:0009617) | 1.61040613 |
132 | Abnormality of macrophages (HP:0004311) | 1.61005489 |
133 | Hyporeflexia of lower limbs (HP:0002600) | 1.60978783 |
134 | Rectal prolapse (HP:0002035) | 1.60869830 |
135 | Striae distensae (HP:0001065) | 1.59834179 |
136 | Nonimmune hydrops fetalis (HP:0001790) | 1.59473348 |
137 | Joint laxity (HP:0001388) | 1.59193423 |
138 | Deep philtrum (HP:0002002) | 1.58640264 |
139 | Chronic otitis media (HP:0000389) | 1.58457097 |
140 | Nephritis (HP:0000123) | 1.58391846 |
141 | Severe short stature (HP:0003510) | 1.58216512 |
142 | Asymmetric septal hypertrophy (HP:0001670) | 1.58077501 |
143 | Ovoid vertebral bodies (HP:0003300) | 1.57986813 |
144 | Bladder diverticulum (HP:0000015) | 1.56293652 |
145 | Periodontitis (HP:0000704) | 1.55368889 |
146 | Orthostatic hypotension (HP:0001278) | 1.54164895 |
147 | Abnormal glucose tolerance (HP:0001952) | 1.52618679 |
148 | Increased variability in muscle fiber diameter (HP:0003557) | 1.52602605 |
149 | Spinal cord compression (HP:0002176) | 1.52507168 |
150 | Acute myeloid leukemia (HP:0004808) | 1.52437451 |
151 | Abnormality of skeletal muscle fiber size (HP:0012084) | 1.49246622 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TRIB3 | 3.93278017 |
2 | ERN1 | 3.69966373 |
3 | PKN2 | 2.80051749 |
4 | PRPF4B | 2.61682507 |
5 | EPHB1 | 2.46830715 |
6 | EEF2K | 2.38355891 |
7 | IRAK3 | 2.17820617 |
8 | STK10 | 2.16005390 |
9 | SIK1 | 2.15034166 |
10 | PTK6 | 2.12417608 |
11 | TTN | 2.08097208 |
12 | MAP4K1 | 2.01821724 |
13 | ICK | 1.97059903 |
14 | LRRK2 | 1.95605831 |
15 | MAP3K10 | 1.94584784 |
16 | FGFR4 | 1.94036918 |
17 | KSR2 | 1.76143222 |
18 | SMG1 | 1.68605621 |
19 | RIPK1 | 1.68597780 |
20 | TAOK3 | 1.67932486 |
21 | RIPK4 | 1.65990821 |
22 | LATS1 | 1.61912565 |
23 | MAP3K13 | 1.54302821 |
24 | JAK3 | 1.51541672 |
25 | TGFBR2 | 1.46901782 |
26 | TYK2 | 1.45875127 |
27 | PDGFRA | 1.45208304 |
28 | CDK12 | 1.42617699 |
29 | MAP3K6 | 1.41834265 |
30 | PTK2 | 1.39963344 |
31 | RPS6KA4 | 1.36065695 |
32 | ZAP70 | 1.35724275 |
33 | TBK1 | 1.33674154 |
34 | CDK6 | 1.30417663 |
35 | BMPR2 | 1.30353808 |
36 | JAK1 | 1.28337677 |
37 | SCYL2 | 1.27804885 |
38 | BMX | 1.26501983 |
39 | LMTK2 | 1.26441124 |
40 | EPHA3 | 1.23215163 |
41 | YES1 | 1.22983093 |
42 | EIF2AK1 | 1.21485211 |
43 | EPHA2 | 1.21130926 |
44 | FLT3 | 1.19408062 |
45 | LATS2 | 1.18204345 |
46 | ITK | 1.16117612 |
47 | NEK9 | 1.14875685 |
48 | KDR | 1.08966703 |
49 | MAP3K3 | 1.07675872 |
50 | CSK | 1.05875321 |
51 | MAP2K3 | 1.05809658 |
52 | PAK4 | 1.05634964 |
53 | TESK1 | 1.04309562 |
54 | TRPM7 | 1.03269980 |
55 | MET | 1.01880403 |
56 | DMPK | 0.99945803 |
57 | PAK2 | 0.99786495 |
58 | CAMK1D | 0.99756909 |
59 | STK3 | 0.99716099 |
60 | NME2 | 0.98195687 |
61 | TESK2 | 0.97227243 |
62 | FGFR3 | 0.94152788 |
63 | DDR2 | 0.93412896 |
64 | PDGFRB | 0.90822805 |
65 | FRK | 0.89652218 |
66 | MTOR | 0.87995814 |
67 | DYRK1B | 0.85461446 |
68 | MST4 | 0.85245028 |
69 | CDC42BPA | 0.85088934 |
70 | BTK | 0.84550425 |
71 | CLK1 | 0.84334244 |
72 | EIF2AK3 | 0.83234478 |
73 | TAOK1 | 0.81231386 |
74 | MYLK | 0.80820806 |
75 | MAP2K2 | 0.79503319 |
76 | MAP3K8 | 0.79232777 |
77 | MAP3K2 | 0.79127691 |
78 | JAK2 | 0.78493994 |
79 | MST1R | 0.78281136 |
80 | STK24 | 0.77822165 |
81 | HCK | 0.76671741 |
82 | BLK | 0.75338710 |
83 | BRD4 | 0.74538192 |
84 | MAPKAPK3 | 0.73627490 |
85 | HIPK2 | 0.72342388 |
86 | CHUK | 0.71376042 |
87 | KIT | 0.70707332 |
88 | TTK | 0.70355558 |
89 | SIK3 | 0.69382881 |
90 | CAMK1G | 0.68010695 |
91 | FER | 0.67354928 |
92 | RPS6KB2 | 0.66780867 |
93 | STK38 | 0.66582950 |
94 | PIK3CG | 0.66285916 |
95 | PRKG2 | 0.66059850 |
96 | RET | 0.65848672 |
97 | PBK | 0.65360977 |
98 | ERBB3 | 0.64635750 |
99 | KSR1 | 0.64602675 |
100 | MAP3K7 | 0.64236303 |
101 | PDPK1 | 0.63192890 |
102 | MAP3K12 | 0.61485012 |
103 | MAP3K11 | 0.61279505 |
104 | RAF1 | 0.61065634 |
105 | MAP3K1 | 0.60290169 |
106 | TGFBR1 | 0.59135849 |
107 | PIM2 | 0.57684231 |
108 | NTRK1 | 0.57634625 |
109 | LCK | 0.57519597 |
110 | IKBKE | 0.56949695 |
111 | GRK6 | 0.56054612 |
112 | CSF1R | 0.55606046 |
113 | NEK6 | 0.55171167 |
114 | FGFR1 | 0.54990166 |
115 | MAP3K14 | 0.54476887 |
116 | ALK | 0.53088854 |
117 | TAOK2 | 0.52790865 |
118 | PIM1 | 0.51647550 |
119 | PRKD1 | 0.51477734 |
120 | PRKCH | 0.51197364 |
121 | MOS | 0.51168904 |
122 | RPS6KA2 | 0.51107211 |
123 | NLK | 0.49247412 |
124 | EGFR | 0.48811057 |
125 | MAPKAPK2 | 0.47871878 |
126 | CDK4 | 0.47019429 |
127 | IKBKB | 0.46976990 |
128 | PAK3 | 0.44200355 |
129 | GSK3A | 0.43779540 |
130 | ERBB4 | 0.43773220 |
131 | CDK9 | 0.41975273 |
132 | EPHB2 | 0.41940669 |
133 | AKT3 | 0.41834652 |
134 | BCKDK | 0.41302872 |
135 | LIMK1 | 0.40576363 |
136 | MAPK11 | 0.40525322 |
137 | ABL2 | 0.39481847 |
138 | NEK1 | 0.39292990 |
139 | MARK2 | 0.38447802 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.97703327 |
2 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.76030594 |
3 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.73346308 |
4 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 1.63985559 |
5 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 1.60525241 |
6 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.55129751 |
7 | ECM-receptor interaction_Homo sapiens_hsa04512 | 1.54469748 |
8 | Leishmaniasis_Homo sapiens_hsa05140 | 1.52379277 |
9 | Small cell lung cancer_Homo sapiens_hsa05222 | 1.51498720 |
10 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.50678562 |
11 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.47997350 |
12 | Focal adhesion_Homo sapiens_hsa04510 | 1.42806533 |
13 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.42232532 |
14 | Osteoclast differentiation_Homo sapiens_hsa04380 | 1.39870495 |
15 | Amoebiasis_Homo sapiens_hsa05146 | 1.32924497 |
16 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 1.28560164 |
17 | Adherens junction_Homo sapiens_hsa04520 | 1.27922996 |
18 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.26625545 |
19 | Lysosome_Homo sapiens_hsa04142 | 1.26588593 |
20 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 1.26416590 |
21 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 1.26235551 |
22 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 1.26212835 |
23 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 1.25581825 |
24 | Endometrial cancer_Homo sapiens_hsa05213 | 1.22915078 |
25 | Fat digestion and absorption_Homo sapiens_hsa04975 | 1.15695780 |
26 | Shigellosis_Homo sapiens_hsa05131 | 1.14639049 |
27 | Pancreatic cancer_Homo sapiens_hsa05212 | 1.13466048 |
28 | Bladder cancer_Homo sapiens_hsa05219 | 1.12533154 |
29 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.12462408 |
30 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.12219811 |
31 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 1.12095604 |
32 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 1.11416764 |
33 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 1.11049710 |
34 | Fatty acid degradation_Homo sapiens_hsa00071 | 1.10351925 |
35 | Insulin resistance_Homo sapiens_hsa04931 | 1.09791035 |
36 | Lysine degradation_Homo sapiens_hsa00310 | 1.09193866 |
37 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.08461641 |
38 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 1.08123649 |
39 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.07518260 |
40 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.06269507 |
41 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.05546609 |
42 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.03301142 |
43 | Malaria_Homo sapiens_hsa05144 | 1.02646100 |
44 | Viral myocarditis_Homo sapiens_hsa05416 | 1.02453432 |
45 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 1.01713711 |
46 | Measles_Homo sapiens_hsa05162 | 1.01686790 |
47 | Galactose metabolism_Homo sapiens_hsa00052 | 1.00993058 |
48 | Apoptosis_Homo sapiens_hsa04210 | 1.00551373 |
49 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.99502297 |
50 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.99291184 |
51 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.97100220 |
52 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.97089726 |
53 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.96088786 |
54 | Prion diseases_Homo sapiens_hsa05020 | 0.95747351 |
55 | Other glycan degradation_Homo sapiens_hsa00511 | 0.94823749 |
56 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.94611452 |
57 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.92514742 |
58 | Platelet activation_Homo sapiens_hsa04611 | 0.91622455 |
59 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.91548277 |
60 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.91067744 |
61 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.90932025 |
62 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.90791802 |
63 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.90301871 |
64 | Hepatitis B_Homo sapiens_hsa05161 | 0.89857918 |
65 | Pertussis_Homo sapiens_hsa05133 | 0.89142462 |
66 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.89020528 |
67 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.88958440 |
68 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.86978161 |
69 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.86903506 |
70 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.86288876 |
71 | Glioma_Homo sapiens_hsa05214 | 0.86185344 |
72 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.84816213 |
73 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.83707089 |
74 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.83566722 |
75 | Legionellosis_Homo sapiens_hsa05134 | 0.83047621 |
76 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.82888089 |
77 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.82677721 |
78 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.80970682 |
79 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.79974816 |
80 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.79495292 |
81 | Tuberculosis_Homo sapiens_hsa05152 | 0.79493746 |
82 | Histidine metabolism_Homo sapiens_hsa00340 | 0.77992636 |
83 | Phagosome_Homo sapiens_hsa04145 | 0.77572363 |
84 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.77124475 |
85 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.76590369 |
86 | Prostate cancer_Homo sapiens_hsa05215 | 0.75935297 |
87 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.75547094 |
88 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.73820984 |
89 | Hepatitis C_Homo sapiens_hsa05160 | 0.73506763 |
90 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.73045185 |
91 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.72782677 |
92 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.72673992 |
93 | Bile secretion_Homo sapiens_hsa04976 | 0.72102692 |
94 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.71019234 |
95 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.69799663 |
96 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.69771407 |
97 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.67280652 |
98 | Salmonella infection_Homo sapiens_hsa05132 | 0.67175736 |
99 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.65696538 |
100 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.65369092 |
101 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.64805214 |
102 | Thyroid cancer_Homo sapiens_hsa05216 | 0.64425085 |
103 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.64295129 |
104 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.64109025 |
105 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.64107819 |
106 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.63984243 |
107 | ABC transporters_Homo sapiens_hsa02010 | 0.63944922 |
108 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.63186352 |
109 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.62838427 |
110 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.61258279 |
111 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.60121794 |
112 | Influenza A_Homo sapiens_hsa05164 | 0.59746566 |
113 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.57928360 |
114 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.57780548 |
115 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.57623975 |
116 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.57202257 |
117 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.55806176 |
118 | Carbon metabolism_Homo sapiens_hsa01200 | 0.55609394 |
119 | * Endocytosis_Homo sapiens_hsa04144 | 0.55384789 |
120 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.54760042 |
121 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.54529740 |
122 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.54484202 |
123 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.54432712 |
124 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.53981750 |
125 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.53786233 |
126 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.53744449 |
127 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.51968025 |
128 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.51567919 |
129 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.50612312 |
130 | Colorectal cancer_Homo sapiens_hsa05210 | 0.49188029 |
131 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.48404566 |
132 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.47997859 |
133 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.47638772 |