Rank | Gene Set | Z-score |
---|---|---|
1 | tricarboxylic acid cycle (GO:0006099) | 6.24491432 |
2 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 5.82774356 |
3 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 5.66289325 |
4 | * regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510) | 5.47230170 |
5 | * regulation of acyl-CoA biosynthetic process (GO:0050812) | 5.44994765 |
6 | ATP synthesis coupled proton transport (GO:0015986) | 5.30882420 |
7 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 5.30882420 |
8 | respiratory electron transport chain (GO:0022904) | 5.14721411 |
9 | electron transport chain (GO:0022900) | 4.97523490 |
10 | * regulation of cofactor metabolic process (GO:0051193) | 4.96227287 |
11 | * regulation of coenzyme metabolic process (GO:0051196) | 4.96227287 |
12 | NADH metabolic process (GO:0006734) | 4.83609004 |
13 | positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316) | 4.55075711 |
14 | sarcomere organization (GO:0045214) | 4.16816566 |
15 | cardiac myofibril assembly (GO:0055003) | 4.10195593 |
16 | regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880) | 4.02709359 |
17 | negative regulation of potassium ion transmembrane transporter activity (GO:1901017) | 4.00303615 |
18 | ubiquinone biosynthetic process (GO:0006744) | 3.99052757 |
19 | quinone biosynthetic process (GO:1901663) | 3.99052757 |
20 | * regulation of sulfur metabolic process (GO:0042762) | 3.96120496 |
21 | regulation of cell communication by electrical coupling (GO:0010649) | 3.95901709 |
22 | regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO | 3.94297489 |
23 | chaperone-mediated protein transport (GO:0072321) | 3.88988018 |
24 | succinate metabolic process (GO:0006105) | 3.87185242 |
25 | myofibril assembly (GO:0030239) | 3.77533461 |
26 | oxidative phosphorylation (GO:0006119) | 3.76879310 |
27 | ubiquinone metabolic process (GO:0006743) | 3.70585343 |
28 | regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882) | 3.65864118 |
29 | regulation of sequestering of triglyceride (GO:0010889) | 3.65402028 |
30 | carnitine shuttle (GO:0006853) | 3.58845606 |
31 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.57587792 |
32 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.57587792 |
33 | NADH dehydrogenase complex assembly (GO:0010257) | 3.57587792 |
34 | regulation of sarcomere organization (GO:0060297) | 3.54562524 |
35 | regulation of relaxation of muscle (GO:1901077) | 3.49922306 |
36 | negative regulation of protein localization to cell surface (GO:2000009) | 3.47670145 |
37 | actin-myosin filament sliding (GO:0033275) | 3.42208524 |
38 | muscle filament sliding (GO:0030049) | 3.42208524 |
39 | protein complex biogenesis (GO:0070271) | 3.39649794 |
40 | branched-chain amino acid catabolic process (GO:0009083) | 3.36219735 |
41 | aspartate family amino acid catabolic process (GO:0009068) | 3.35704576 |
42 | behavioral response to nicotine (GO:0035095) | 3.33585402 |
43 | cellular ketone body metabolic process (GO:0046950) | 3.30873241 |
44 | sarcoplasmic reticulum calcium ion transport (GO:0070296) | 3.28786769 |
45 | negative regulation of potassium ion transmembrane transport (GO:1901380) | 3.28324695 |
46 | regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314) | 3.27513778 |
47 | regulation of skeletal muscle contraction (GO:0014819) | 3.26351428 |
48 | fatty acid transmembrane transport (GO:1902001) | 3.24519115 |
49 | cardiac muscle contraction (GO:0060048) | 3.22854646 |
50 | inner mitochondrial membrane organization (GO:0007007) | 3.18443502 |
51 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.18144819 |
52 | ATP biosynthetic process (GO:0006754) | 3.17295871 |
53 | regulation of actin filament-based movement (GO:1903115) | 3.15326884 |
54 | cardiac muscle cell development (GO:0055013) | 3.15073970 |
55 | aerobic respiration (GO:0009060) | 3.13123755 |
56 | cardiac muscle hypertrophy (GO:0003300) | 3.07359246 |
57 | response to epinephrine (GO:0071871) | 3.05798280 |
58 | heart process (GO:0003015) | 3.05231767 |
59 | heart contraction (GO:0060047) | 3.05231767 |
60 | acetyl-CoA metabolic process (GO:0006084) | 3.04954894 |
61 | hydrogen ion transmembrane transport (GO:1902600) | 3.04564537 |
62 | ventricular cardiac muscle cell action potential (GO:0086005) | 3.00364884 |
63 | oxaloacetate metabolic process (GO:0006107) | 2.98454243 |
64 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 2.92630245 |
65 | regulation of membrane repolarization (GO:0060306) | 2.91426842 |
66 | striated muscle hypertrophy (GO:0014897) | 2.90167602 |
67 | neuron cell-cell adhesion (GO:0007158) | 2.89871988 |
68 | detection of calcium ion (GO:0005513) | 2.87434958 |
69 | fatty acid beta-oxidation (GO:0006635) | 2.86170925 |
70 | actin-mediated cell contraction (GO:0070252) | 2.85806858 |
71 | regulation of glucokinase activity (GO:0033131) | 2.85624882 |
72 | regulation of hexokinase activity (GO:1903299) | 2.85624882 |
73 | proteasome assembly (GO:0043248) | 2.85561178 |
74 | cardiac cell development (GO:0055006) | 2.85364533 |
75 | striated muscle contraction (GO:0006941) | 2.85260215 |
76 | IMP metabolic process (GO:0046040) | 2.85118626 |
77 | cellular response to epinephrine stimulus (GO:0071872) | 2.82828075 |
78 | 2-oxoglutarate metabolic process (GO:0006103) | 2.82727097 |
79 | ketone body metabolic process (GO:1902224) | 2.82212656 |
80 | skeletal muscle contraction (GO:0003009) | 2.81494265 |
81 | lipid particle organization (GO:0034389) | 2.80817646 |
82 | protein-cofactor linkage (GO:0018065) | 2.80694364 |
83 | response to stimulus involved in regulation of muscle adaptation (GO:0014874) | 2.79351044 |
84 | regulation of striated muscle contraction (GO:0006942) | 2.78365536 |
85 | lysine metabolic process (GO:0006553) | 2.78199781 |
86 | lysine catabolic process (GO:0006554) | 2.78199781 |
87 | response to pheromone (GO:0019236) | 2.77168411 |
88 | presynaptic membrane assembly (GO:0097105) | 2.74469433 |
89 | proton transport (GO:0015992) | 2.74283140 |
90 | maturation of 5.8S rRNA (GO:0000460) | 2.73609301 |
91 | hydrogen transport (GO:0006818) | 2.73189450 |
92 | regulation of mitochondrial translation (GO:0070129) | 2.72852939 |
93 | positive regulation of mitochondrial calcium ion concentration (GO:0051561) | 2.72731863 |
94 | pyrimidine nucleobase catabolic process (GO:0006208) | 2.71604871 |
95 | protein K6-linked ubiquitination (GO:0085020) | 2.71268840 |
96 | carnitine transmembrane transport (GO:1902603) | 2.70971609 |
97 | cardiac muscle tissue morphogenesis (GO:0055008) | 2.70870555 |
98 | cellular respiration (GO:0045333) | 2.70719681 |
99 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 2.69946295 |
100 | biotin metabolic process (GO:0006768) | 2.69289294 |
101 | vocalization behavior (GO:0071625) | 2.69200616 |
102 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.68168216 |
103 | ATP hydrolysis coupled proton transport (GO:0015991) | 2.67913249 |
104 | energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988) | 2.67913249 |
105 | adult heart development (GO:0007512) | 2.67646179 |
106 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 2.67631690 |
107 | response to muscle activity (GO:0014850) | 2.66414510 |
108 | positive regulation of mitochondrial fission (GO:0090141) | 2.65806151 |
109 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 2.63259108 |
110 | creatine metabolic process (GO:0006600) | 2.63150924 |
111 | branched-chain amino acid metabolic process (GO:0009081) | 2.61551066 |
112 | protein deneddylation (GO:0000338) | 2.60904347 |
113 | cullin deneddylation (GO:0010388) | 2.60150926 |
114 | positive regulation of heart rate (GO:0010460) | 2.60130463 |
115 | IMP biosynthetic process (GO:0006188) | 2.57310179 |
116 | response to caffeine (GO:0031000) | 2.47864079 |
117 | mitochondrial RNA metabolic process (GO:0000959) | 2.46095390 |
118 | intracellular protein transmembrane import (GO:0044743) | 2.41994661 |
119 | DNA damage response, detection of DNA damage (GO:0042769) | 2.38978847 |
120 | gluconeogenesis (GO:0006094) | 2.38256310 |
121 | C4-dicarboxylate transport (GO:0015740) | 2.37993116 |
122 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 2.32936299 |
123 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 2.32936299 |
124 | organelle disassembly (GO:1903008) | 2.29478703 |
125 | ribonucleoprotein complex disassembly (GO:0032988) | 2.29439053 |
126 | DNA double-strand break processing (GO:0000729) | 2.28562164 |
127 | nonmotile primary cilium assembly (GO:0035058) | 2.28493054 |
128 | positive regulation of potassium ion transmembrane transporter activity (GO:1901018) | 2.27951441 |
129 | actin filament-based movement (GO:0030048) | 2.25365320 |
130 | chromatin remodeling at centromere (GO:0031055) | 2.24015279 |
131 | CENP-A containing nucleosome assembly (GO:0034080) | 2.21680893 |
132 | peptidyl-histidine modification (GO:0018202) | 2.21678520 |
133 | muscle cell cellular homeostasis (GO:0046716) | 2.21308173 |
134 | L-serine metabolic process (GO:0006563) | 2.19874657 |
135 | water-soluble vitamin biosynthetic process (GO:0042364) | 2.19843277 |
136 | respiratory chain complex IV assembly (GO:0008535) | 2.19647739 |
137 | response to inactivity (GO:0014854) | 2.18933940 |
138 | amino acid activation (GO:0043038) | 2.18587506 |
139 | tRNA aminoacylation (GO:0043039) | 2.18587506 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EZH2_22144423_ChIP-Seq_EOC_Human | 5.07320949 |
2 | GBX2_23144817_ChIP-Seq_PC3_Human | 3.95559109 |
3 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.97601447 |
4 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.94705869 |
5 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.93867481 |
6 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.76896446 |
7 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 2.69290716 |
8 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.52603558 |
9 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.42401938 |
10 | VDR_22108803_ChIP-Seq_LS180_Human | 2.40457256 |
11 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.36608696 |
12 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.27205198 |
13 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 2.24544480 |
14 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.18654664 |
15 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 2.16040496 |
16 | * ELK1_19687146_ChIP-ChIP_HELA_Human | 2.09459008 |
17 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 2.08496742 |
18 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.06139701 |
19 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.85830469 |
20 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.85323440 |
21 | EWS_26573619_Chip-Seq_HEK293_Human | 1.84366842 |
22 | FUS_26573619_Chip-Seq_HEK293_Human | 1.78136297 |
23 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.72293880 |
24 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.69840189 |
25 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 1.69208028 |
26 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.67483594 |
27 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.65251538 |
28 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.65034122 |
29 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.63954808 |
30 | P300_19829295_ChIP-Seq_ESCs_Human | 1.63208541 |
31 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.62365949 |
32 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.60846057 |
33 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.58926948 |
34 | * UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.56551888 |
35 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.55412313 |
36 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.55028228 |
37 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.52956730 |
38 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.52764988 |
39 | * MYC_18940864_ChIP-ChIP_HL60_Human | 1.51525669 |
40 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.49346315 |
41 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.49069137 |
42 | * YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.48157286 |
43 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.47552129 |
44 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.45377250 |
45 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.44591497 |
46 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.43779046 |
47 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.43662086 |
48 | * SMAD4_21799915_ChIP-Seq_A2780_Human | 1.43503457 |
49 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.43377033 |
50 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.38740272 |
51 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.35573224 |
52 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.34781024 |
53 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.33476079 |
54 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.31665994 |
55 | * OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.31043034 |
56 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.29817524 |
57 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.29532369 |
58 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 1.29364908 |
59 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.28813119 |
60 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.26716567 |
61 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.25908402 |
62 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.25108239 |
63 | * FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 1.24666984 |
64 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.24486887 |
65 | * E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.23792268 |
66 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.23158717 |
67 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.21979883 |
68 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.20550155 |
69 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.20219211 |
70 | E2F7_22180533_ChIP-Seq_HELA_Human | 1.19861733 |
71 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.18729899 |
72 | * ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.17900659 |
73 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.17391872 |
74 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.16220226 |
75 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.16220226 |
76 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.15956014 |
77 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.14125129 |
78 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.13316495 |
79 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.13073417 |
80 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.12309368 |
81 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.12102509 |
82 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.11978809 |
83 | * NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.11775922 |
84 | AR_25329375_ChIP-Seq_VCAP_Human | 1.11750192 |
85 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.11683164 |
86 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 1.11621770 |
87 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.11447912 |
88 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.10680925 |
89 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.09864186 |
90 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.09471039 |
91 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.08845615 |
92 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.08171889 |
93 | * STAT3_23295773_ChIP-Seq_U87_Human | 1.08017820 |
94 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 1.07152825 |
95 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.06832521 |
96 | * NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.06634122 |
97 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.06319136 |
98 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.06041709 |
99 | * TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.06011141 |
100 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.05510750 |
101 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.05509633 |
102 | * TCF4_23295773_ChIP-Seq_U87_Human | 1.05444493 |
103 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.05346590 |
104 | SOX9_26525672_Chip-Seq_HEART_Mouse | 1.04522239 |
105 | * EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.04130326 |
106 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.04119351 |
107 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.04119351 |
108 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.03834985 |
109 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.03411743 |
110 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 1.03389468 |
111 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.03368915 |
112 | * E2F1_18555785_Chip-Seq_ESCs_Mouse | 1.02647283 |
113 | * STAT3_18555785_Chip-Seq_ESCs_Mouse | 1.02449663 |
114 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.02106139 |
115 | JUN_21703547_ChIP-Seq_K562_Human | 1.02036016 |
116 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.01587483 |
117 | * P53_22387025_ChIP-Seq_ESCs_Mouse | 1.01259458 |
118 | MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 1.01064272 |
119 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.00999968 |
120 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.00647579 |
121 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.00647579 |
122 | * AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.00466211 |
123 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 1.00133174 |
124 | TP53_22573176_ChIP-Seq_HFKS_Human | 0.99579130 |
125 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 0.99265189 |
126 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 0.99133269 |
127 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 0.99041194 |
128 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 0.98805944 |
129 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 0.98598348 |
130 | MEF2A_21415370_ChIP-Seq_HL-1_Mouse | 0.98485355 |
131 | * SUZ12_18555785_Chip-Seq_ESCs_Mouse | 0.98407592 |
132 | * EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse | 0.97295421 |
133 | TAL1_26923725_Chip-Seq_HPCs_Mouse | 0.97139714 |
134 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.96314540 |
135 | * SOX2_18555785_Chip-Seq_ESCs_Mouse | 0.95933635 |
136 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 0.95398865 |
137 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 0.94859505 |
138 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 0.93993318 |
139 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.88898461 |
140 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 0.87926282 |
141 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 0.87402578 |
142 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 0.86633230 |
143 | * CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 0.86188538 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003646_muscle_fatigue | 5.32141221 |
2 | MP0002837_dystrophic_cardiac_calcinosis | 4.96905739 |
3 | MP0000751_myopathy | 3.56482338 |
4 | MP0004215_abnormal_myocardial_fiber | 3.40956277 |
5 | MP0004084_abnormal_cardiac_muscle | 3.14336427 |
6 | MP0003880_abnormal_central_pattern | 3.03223258 |
7 | MP0004036_abnormal_muscle_relaxation | 2.89617185 |
8 | MP0000749_muscle_degeneration | 2.71668809 |
9 | MP0005330_cardiomyopathy | 2.44153543 |
10 | MP0001529_abnormal_vocalization | 2.36771384 |
11 | MP0006036_abnormal_mitochondrial_physio | 2.33241071 |
12 | MP0004145_abnormal_muscle_electrophysio | 2.27919952 |
13 | MP0004130_abnormal_muscle_cell | 2.22512844 |
14 | MP0003137_abnormal_impulse_conducting | 2.09449892 |
15 | MP0004484_altered_response_of | 2.09286743 |
16 | MP0005620_abnormal_muscle_contractility | 1.99159865 |
17 | MP0002972_abnormal_cardiac_muscle | 1.96604138 |
18 | MP0004859_abnormal_synaptic_plasticity | 1.96289889 |
19 | MP0006035_abnormal_mitochondrial_morpho | 1.75735053 |
20 | MP0004087_abnormal_muscle_fiber | 1.75137441 |
21 | MP0002106_abnormal_muscle_physiology | 1.74694775 |
22 | MP0003221_abnormal_cardiomyocyte_apopto | 1.73446705 |
23 | MP0009046_muscle_twitch | 1.70433736 |
24 | MP0003806_abnormal_nucleotide_metabolis | 1.68264782 |
25 | MP0003635_abnormal_synaptic_transmissio | 1.64994222 |
26 | MP0009745_abnormal_behavioral_response | 1.62497783 |
27 | MP0002269_muscular_atrophy | 1.62427841 |
28 | MP0008775_abnormal_heart_ventricle | 1.59329960 |
29 | MP0004270_analgesia | 1.55936343 |
30 | MP0002272_abnormal_nervous_system | 1.55246170 |
31 | MP0002638_abnormal_pupillary_reflex | 1.54407193 |
32 | MP0003950_abnormal_plasma_membrane | 1.51155704 |
33 | MP0002736_abnormal_nociception_after | 1.50675949 |
34 | MP0005670_abnormal_white_adipose | 1.50576853 |
35 | MP0004085_abnormal_heartbeat | 1.49819847 |
36 | MP0006138_congestive_heart_failure | 1.48056239 |
37 | MP0001905_abnormal_dopamine_level | 1.47343525 |
38 | MP0002064_seizures | 1.47111519 |
39 | MP0005385_cardiovascular_system_phenoty | 1.43151641 |
40 | MP0001544_abnormal_cardiovascular_syste | 1.43151641 |
41 | MP0005369_muscle_phenotype | 1.42178512 |
42 | MP0005451_abnormal_body_composition | 1.41953669 |
43 | MP0002332_abnormal_exercise_endurance | 1.38801904 |
44 | MP0002063_abnormal_learning/memory/cond | 1.38126071 |
45 | MP0001440_abnormal_grooming_behavior | 1.38105627 |
46 | MP0008058_abnormal_DNA_repair | 1.37489771 |
47 | MP0002735_abnormal_chemical_nociception | 1.36872287 |
48 | MP0001968_abnormal_touch/_nociception | 1.36230612 |
49 | MP0000759_abnormal_skeletal_muscle | 1.34548648 |
50 | MP0000747_muscle_weakness | 1.34340271 |
51 | MP0003890_abnormal_embryonic-extraembry | 1.33392308 |
52 | MP0004924_abnormal_behavior | 1.33266310 |
53 | MP0005386_behavior/neurological_phenoty | 1.33266310 |
54 | MP0004142_abnormal_muscle_tone | 1.31548364 |
55 | MP0002572_abnormal_emotion/affect_behav | 1.31440810 |
56 | MP0001486_abnormal_startle_reflex | 1.29637066 |
57 | MP0000750_abnormal_muscle_regeneration | 1.29150719 |
58 | MP0003718_maternal_effect | 1.27569566 |
59 | MP0002822_catalepsy | 1.27436578 |
60 | MP0004147_increased_porphyrin_level | 1.27040093 |
61 | MP0005187_abnormal_penis_morphology | 1.26105187 |
62 | MP0002067_abnormal_sensory_capabilities | 1.25792515 |
63 | MP0006072_abnormal_retinal_apoptosis | 1.24903567 |
64 | MP0002234_abnormal_pharynx_morphology | 1.24692157 |
65 | MP0000013_abnormal_adipose_tissue | 1.23087925 |
66 | MP0002938_white_spotting | 1.22594171 |
67 | MP0002102_abnormal_ear_morphology | 1.22075277 |
68 | MP0000372_irregular_coat_pigmentation | 1.20755263 |
69 | MP0005666_abnormal_adipose_tissue | 1.17132466 |
70 | MP0004233_abnormal_muscle_weight | 1.16436080 |
71 | MP0006276_abnormal_autonomic_nervous | 1.16267537 |
72 | MP0009697_abnormal_copulation | 1.14434343 |
73 | MP0008260_abnormal_autophagy | 1.14180331 |
74 | MP0001984_abnormal_olfaction | 1.13413780 |
75 | MP0008877_abnormal_DNA_methylation | 1.13154913 |
76 | MP0002734_abnormal_mechanical_nocicepti | 1.11164558 |
77 | MP0005646_abnormal_pituitary_gland | 1.11095969 |
78 | MP0010030_abnormal_orbit_morphology | 1.09876989 |
79 | MP0005253_abnormal_eye_physiology | 1.07023796 |
80 | MP0003937_abnormal_limbs/digits/tail_de | 1.06596067 |
81 | MP0004133_heterotaxia | 1.05984825 |
82 | MP0002160_abnormal_reproductive_system | 1.04505096 |
83 | MP0002127_abnormal_cardiovascular_syste | 1.04184152 |
84 | MP0003941_abnormal_skin_development | 1.03400887 |
85 | MP0008789_abnormal_olfactory_epithelium | 1.03218046 |
86 | MP0003693_abnormal_embryo_hatching | 1.02339349 |
87 | MP0005085_abnormal_gallbladder_physiolo | 1.01860695 |
88 | MP0003567_abnormal_fetal_cardiomyocyte | 1.01259286 |
89 | MP0001299_abnormal_eye_distance/ | 1.00806170 |
90 | MP0001485_abnormal_pinna_reflex | 0.99487217 |
91 | MP0010630_abnormal_cardiac_muscle | 0.99412187 |
92 | MP0010094_abnormal_chromosome_stability | 0.97772042 |
93 | MP0003186_abnormal_redox_activity | 0.97224286 |
94 | MP0002876_abnormal_thyroid_physiology | 0.95737085 |
95 | MP0000778_abnormal_nervous_system | 0.95347544 |
96 | MP0003122_maternal_imprinting | 0.92445662 |
97 | MP0005266_abnormal_metabolism | 0.91840964 |
98 | MP0004957_abnormal_blastocyst_morpholog | 0.89854859 |
99 | MP0005645_abnormal_hypothalamus_physiol | 0.88757336 |
100 | MP0005551_abnormal_eye_electrophysiolog | 0.87773361 |
101 | MP0003879_abnormal_hair_cell | 0.86965845 |
102 | MP0006292_abnormal_olfactory_placode | 0.86958192 |
103 | MP0001188_hyperpigmentation | 0.85993280 |
104 | MP0000647_abnormal_sebaceous_gland | 0.84420525 |
105 | MP0004043_abnormal_pH_regulation | 0.84362051 |
106 | MP0008875_abnormal_xenobiotic_pharmacok | 0.84041880 |
107 | MP0004185_abnormal_adipocyte_glucose | 0.83664231 |
108 | MP0002090_abnormal_vision | 0.83447260 |
109 | MP0008995_early_reproductive_senescence | 0.82097506 |
110 | MP0008932_abnormal_embryonic_tissue | 0.81789497 |
111 | MP0003315_abnormal_perineum_morphology | 0.81687206 |
112 | MP0002066_abnormal_motor_capabilities/c | 0.81431250 |
113 | MP0003329_amyloid_beta_deposits | 0.81293520 |
114 | MP0005535_abnormal_body_temperature | 0.80828020 |
115 | MP0005423_abnormal_somatic_nervous | 0.80810871 |
116 | MP0001501_abnormal_sleep_pattern | 0.80403494 |
117 | MP0002653_abnormal_ependyma_morphology | 0.80391078 |
118 | MP0002184_abnormal_innervation | 0.77075492 |
119 | MP0005365_abnormal_bile_salt | 0.75574908 |
120 | MP0001727_abnormal_embryo_implantation | 0.73097484 |
121 | MP0002229_neurodegeneration | 0.70843226 |
122 | MP0005332_abnormal_amino_acid | 0.70573229 |
123 | MP0000358_abnormal_cell_content/ | 0.70504035 |
124 | MP0000230_abnormal_systemic_arterial | 0.70451152 |
125 | MP0001661_extended_life_span | 0.69837170 |
126 | MP0003136_yellow_coat_color | 0.68911423 |
127 | MP0005394_taste/olfaction_phenotype | 0.68743614 |
128 | MP0003195_calcinosis | 0.66881877 |
129 | MP0003787_abnormal_imprinting | 0.66835233 |
130 | MP0001970_abnormal_pain_threshold | 0.65044003 |
131 | MP0002882_abnormal_neuron_morphology | 0.64123692 |
132 | MP0005410_abnormal_fertilization | 0.62255934 |
133 | MP0001963_abnormal_hearing_physiology | 0.62212326 |
134 | MP0002971_abnormal_brown_adipose | 0.61885384 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Acute necrotizing encephalopathy (HP:0006965) | 5.10590621 |
2 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.92107316 |
3 | Acute encephalopathy (HP:0006846) | 4.54093852 |
4 | Sudden death (HP:0001699) | 4.29102444 |
5 | Mitochondrial inheritance (HP:0001427) | 4.28599927 |
6 | Progressive macrocephaly (HP:0004481) | 4.28167987 |
7 | Hepatocellular necrosis (HP:0001404) | 4.21492114 |
8 | Hepatic necrosis (HP:0002605) | 4.15533433 |
9 | Exercise-induced myalgia (HP:0003738) | 4.07577256 |
10 | * Increased serum pyruvate (HP:0003542) | 4.07506341 |
11 | * Abnormality of glycolysis (HP:0004366) | 4.07506341 |
12 | Increased CSF lactate (HP:0002490) | 4.03792743 |
13 | Muscle hypertrophy of the lower extremities (HP:0008968) | 3.94203702 |
14 | Calf muscle hypertrophy (HP:0008981) | 3.94104237 |
15 | Focal motor seizures (HP:0011153) | 3.89492836 |
16 | Cerebral edema (HP:0002181) | 3.80135249 |
17 | * Lactic acidosis (HP:0003128) | 3.47963622 |
18 | Exercise-induced muscle cramps (HP:0003710) | 3.38484737 |
19 | * Hyperalaninemia (HP:0003348) | 3.35291179 |
20 | * Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 3.35291179 |
21 | * Abnormality of alanine metabolism (HP:0010916) | 3.35291179 |
22 | Myoglobinuria (HP:0002913) | 3.25224330 |
23 | Atrial fibrillation (HP:0005110) | 3.24828966 |
24 | Increased muscle lipid content (HP:0009058) | 3.21484404 |
25 | Muscle fiber splitting (HP:0003555) | 3.20929909 |
26 | Increased intramyocellular lipid droplets (HP:0012240) | 3.17292747 |
27 | Rimmed vacuoles (HP:0003805) | 3.17027247 |
28 | Ventricular tachycardia (HP:0004756) | 3.14477923 |
29 | Exercise intolerance (HP:0003546) | 3.11883701 |
30 | Abnormality of the calf musculature (HP:0001430) | 3.11102167 |
31 | Type 1 muscle fiber predominance (HP:0003803) | 3.08052829 |
32 | Syncope (HP:0001279) | 3.04086009 |
33 | Primary atrial arrhythmia (HP:0001692) | 2.98852068 |
34 | Increased serum lactate (HP:0002151) | 2.97641054 |
35 | Rhabdomyolysis (HP:0003201) | 2.95592222 |
36 | Respiratory failure (HP:0002878) | 2.95049101 |
37 | Palpitations (HP:0001962) | 2.94631107 |
38 | Lipid accumulation in hepatocytes (HP:0006561) | 2.91457988 |
39 | Supraventricular tachycardia (HP:0004755) | 2.88459514 |
40 | Optic disc pallor (HP:0000543) | 2.84053888 |
41 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.83583811 |
42 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.83583811 |
43 | Increased hepatocellular lipid droplets (HP:0006565) | 2.81729533 |
44 | Pheochromocytoma (HP:0002666) | 2.77645315 |
45 | Supraventricular arrhythmia (HP:0005115) | 2.77533611 |
46 | Hyperventilation (HP:0002883) | 2.76607989 |
47 | Lipoatrophy (HP:0100578) | 2.72691342 |
48 | Distal arthrogryposis (HP:0005684) | 2.66428087 |
49 | Leukodystrophy (HP:0002415) | 2.61115614 |
50 | Neuroendocrine neoplasm (HP:0100634) | 2.60063944 |
51 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 2.58357325 |
52 | Dicarboxylic aciduria (HP:0003215) | 2.58357325 |
53 | Abnormality of the left ventricular outflow tract (HP:0011103) | 2.53741608 |
54 | Subaortic stenosis (HP:0001682) | 2.53741608 |
55 | Abnormality of fatty-acid metabolism (HP:0004359) | 2.51388011 |
56 | Lethargy (HP:0001254) | 2.48943311 |
57 | Bundle branch block (HP:0011710) | 2.48119767 |
58 | 3-Methylglutaconic aciduria (HP:0003535) | 2.43856945 |
59 | Left ventricular hypertrophy (HP:0001712) | 2.42362421 |
60 | Hyperglycinuria (HP:0003108) | 2.41013282 |
61 | Ketoacidosis (HP:0001993) | 2.40304973 |
62 | EMG: myopathic abnormalities (HP:0003458) | 2.33337868 |
63 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.33081189 |
64 | Dilated cardiomyopathy (HP:0001644) | 2.32711627 |
65 | CNS demyelination (HP:0007305) | 2.28545905 |
66 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.28328175 |
67 | Abnormality of glycine metabolism (HP:0010895) | 2.23593628 |
68 | Abnormality of serine family amino acid metabolism (HP:0010894) | 2.23593628 |
69 | Prolonged QT interval (HP:0001657) | 2.23265804 |
70 | Medial flaring of the eyebrow (HP:0010747) | 2.23075834 |
71 | Atonic seizures (HP:0010819) | 2.22129893 |
72 | Methylmalonic acidemia (HP:0002912) | 2.21970269 |
73 | Neck muscle weakness (HP:0000467) | 2.19479653 |
74 | Progressive external ophthalmoplegia (HP:0000590) | 2.15305585 |
75 | Epileptic encephalopathy (HP:0200134) | 2.14137140 |
76 | Ragged-red muscle fibers (HP:0003200) | 2.12838866 |
77 | Muscle fiber inclusion bodies (HP:0100299) | 2.12625360 |
78 | Ventricular arrhythmia (HP:0004308) | 2.12582408 |
79 | Hyporeflexia of lower limbs (HP:0002600) | 2.12125491 |
80 | Myotonia (HP:0002486) | 2.11106151 |
81 | Febrile seizures (HP:0002373) | 2.10562853 |
82 | Renal Fanconi syndrome (HP:0001994) | 2.10065185 |
83 | Muscle fiber cytoplasmatic inclusion bodies (HP:0100303) | 2.07319282 |
84 | Gait imbalance (HP:0002141) | 2.06438794 |
85 | Methylmalonic aciduria (HP:0012120) | 2.06293838 |
86 | Ketosis (HP:0001946) | 2.04039403 |
87 | Congenital primary aphakia (HP:0007707) | 2.02568711 |
88 | Hyperglycinemia (HP:0002154) | 2.01505655 |
89 | Absent phalangeal crease (HP:0006109) | 1.99780591 |
90 | Focal seizures (HP:0007359) | 1.95951708 |
91 | Muscle stiffness (HP:0003552) | 1.95820932 |
92 | Microvesicular hepatic steatosis (HP:0001414) | 1.95649873 |
93 | Heart block (HP:0012722) | 1.95390521 |
94 | Hyperammonemia (HP:0001987) | 1.95273756 |
95 | Absence seizures (HP:0002121) | 1.94874411 |
96 | Nemaline bodies (HP:0003798) | 1.94126799 |
97 | Calcaneovalgus deformity (HP:0001848) | 1.93621045 |
98 | Abnormality of long-chain fatty-acid metabolism (HP:0010964) | 1.92477688 |
99 | X-linked dominant inheritance (HP:0001423) | 1.92275730 |
100 | Difficulty running (HP:0009046) | 1.92268823 |
101 | Type II lissencephaly (HP:0007260) | 1.91987953 |
102 | Abnormal finger flexion creases (HP:0006143) | 1.91553556 |
103 | Generalized tonic-clonic seizures (HP:0002069) | 1.91217664 |
104 | Progressive inability to walk (HP:0002505) | 1.90636917 |
105 | Right ventricular cardiomyopathy (HP:0011663) | 1.89605207 |
106 | Respiratory difficulties (HP:0002880) | 1.89559171 |
107 | Nephrogenic diabetes insipidus (HP:0009806) | 1.88834323 |
108 | Dialeptic seizures (HP:0011146) | 1.86023702 |
109 | Frequent falls (HP:0002359) | 1.84468335 |
110 | Vomiting (HP:0002013) | 1.83105647 |
111 | Central scotoma (HP:0000603) | 1.82956767 |
112 | Hypoglycemic coma (HP:0001325) | 1.82617796 |
113 | * Abnormality of serum amino acid levels (HP:0003112) | 1.82065287 |
114 | Neoplasm of the adrenal gland (HP:0100631) | 1.81927306 |
115 | Abnormal EKG (HP:0003115) | 1.81883016 |
116 | Broad-based gait (HP:0002136) | 1.81517399 |
117 | Renal cortical cysts (HP:0000803) | 1.81134037 |
118 | Ventricular fibrillation (HP:0001663) | 1.80497438 |
119 | Myopathic facies (HP:0002058) | 1.78972320 |
120 | Limb-girdle muscle atrophy (HP:0003797) | 1.77615108 |
121 | Shoulder girdle muscle weakness (HP:0003547) | 1.76504842 |
122 | Birth length less than 3rd percentile (HP:0003561) | 1.76071542 |
123 | Pancreatic fibrosis (HP:0100732) | 1.76027906 |
124 | Inability to walk (HP:0002540) | 1.75926602 |
125 | Areflexia of lower limbs (HP:0002522) | 1.73588347 |
126 | Abnormality of the labia minora (HP:0012880) | 1.71809687 |
127 | Pancreatic cysts (HP:0001737) | 1.71174816 |
128 | Hyperinsulinemic hypoglycemia (HP:0000825) | 1.69659252 |
129 | Deformed tarsal bones (HP:0008119) | 1.69476602 |
130 | Genital tract atresia (HP:0001827) | 1.68522385 |
131 | Molar tooth sign on MRI (HP:0002419) | 1.65399048 |
132 | Abnormality of midbrain morphology (HP:0002418) | 1.65399048 |
133 | Type I transferrin isoform profile (HP:0003642) | 1.62709801 |
134 | Vaginal atresia (HP:0000148) | 1.62359655 |
135 | Delayed gross motor development (HP:0002194) | 1.60659366 |
136 | Degeneration of anterior horn cells (HP:0002398) | 1.59177803 |
137 | Abnormality of the anterior horn cell (HP:0006802) | 1.59177803 |
138 | Cerebellar dysplasia (HP:0007033) | 1.58531270 |
139 | Poor coordination (HP:0002370) | 1.58101865 |
140 | EMG: neuropathic changes (HP:0003445) | 1.57944122 |
Rank | Gene Set | Z-score |
---|---|---|
1 | PDK4 | 4.08677654 |
2 | PDK3 | 4.08677654 |
3 | CASK | 4.02776441 |
4 | OBSCN | 2.84050002 |
5 | PHKG1 | 2.47058843 |
6 | PHKG2 | 2.47058843 |
7 | PDK2 | 2.46926621 |
8 | MAP3K4 | 2.41710855 |
9 | MUSK | 2.39940783 |
10 | MAP2K7 | 2.37634601 |
11 | EPHA4 | 2.28005350 |
12 | NEK1 | 2.25880941 |
13 | MYLK | 2.07194554 |
14 | PINK1 | 1.96662678 |
15 | MAP3K12 | 1.94769435 |
16 | BCKDK | 1.88746576 |
17 | MAP2K4 | 1.84631346 |
18 | EIF2AK3 | 1.81134927 |
19 | MAP3K6 | 1.79437330 |
20 | NME1 | 1.72434307 |
21 | ERBB3 | 1.71444243 |
22 | TTN | 1.64468079 |
23 | PRPF4B | 1.61648746 |
24 | MARK1 | 1.60084152 |
25 | LMTK2 | 1.55940654 |
26 | MAP4K2 | 1.54953045 |
27 | PLK2 | 1.54087295 |
28 | CCNB1 | 1.51921053 |
29 | OXSR1 | 1.51786927 |
30 | NTRK3 | 1.49470423 |
31 | WEE1 | 1.39686310 |
32 | AKT3 | 1.36025557 |
33 | STK39 | 1.35250979 |
34 | LIMK1 | 1.34644775 |
35 | GRK7 | 1.33656548 |
36 | STK38L | 1.33106808 |
37 | ADRBK2 | 1.30630979 |
38 | MAP3K9 | 1.29901310 |
39 | TNIK | 1.28862554 |
40 | STK16 | 1.23090631 |
41 | BRSK2 | 1.22100198 |
42 | ERBB4 | 1.21249828 |
43 | BRAF | 1.19833941 |
44 | BMPR2 | 1.19644968 |
45 | TRIM28 | 1.16471581 |
46 | CAMK2A | 1.16047430 |
47 | PIK3CA | 1.15587961 |
48 | WNK3 | 1.13673036 |
49 | BCR | 1.12227835 |
50 | PKN1 | 1.07291946 |
51 | MAPK13 | 1.06561361 |
52 | PNCK | 1.06247813 |
53 | CDC7 | 1.04431635 |
54 | CDK19 | 1.03342539 |
55 | CAMK2D | 1.02330731 |
56 | ACVR1B | 0.93608525 |
57 | VRK1 | 0.93086431 |
58 | DYRK2 | 0.92112909 |
59 | EIF2AK1 | 0.91218930 |
60 | DYRK3 | 0.89221350 |
61 | DMPK | 0.88835050 |
62 | CSNK1G1 | 0.87916255 |
63 | FRK | 0.85707851 |
64 | EPHA3 | 0.85466141 |
65 | RPS6KA4 | 0.84992600 |
66 | NUAK1 | 0.83405616 |
67 | PLK1 | 0.83266146 |
68 | ZAK | 0.82608776 |
69 | CAMK2B | 0.80203131 |
70 | PAK3 | 0.80096012 |
71 | MINK1 | 0.79448476 |
72 | CSNK1G3 | 0.79189176 |
73 | KSR1 | 0.78555984 |
74 | PLK4 | 0.76572856 |
75 | TSSK6 | 0.74519907 |
76 | GRK1 | 0.74442972 |
77 | MAPKAPK5 | 0.73474890 |
78 | PRKCE | 0.71201137 |
79 | MKNK1 | 0.71181948 |
80 | TTK | 0.70970201 |
81 | VRK2 | 0.70445915 |
82 | STK24 | 0.70344491 |
83 | MAP3K5 | 0.70240273 |
84 | SGK223 | 0.69919328 |
85 | SGK494 | 0.69919328 |
86 | CSNK1A1L | 0.69556675 |
87 | CAMK2G | 0.69385391 |
88 | BUB1 | 0.67200666 |
89 | PAK6 | 0.67068362 |
90 | NEK2 | 0.66948804 |
91 | TIE1 | 0.65807453 |
92 | WNK4 | 0.65587199 |
93 | ROCK2 | 0.65018594 |
94 | MET | 0.65000558 |
95 | MAPK12 | 0.64770494 |
96 | ARAF | 0.64677630 |
97 | CAMKK2 | 0.64245054 |
98 | PRKCG | 0.64137494 |
99 | BMPR1B | 0.61532985 |
100 | LATS2 | 0.57739284 |
101 | PRKAA1 | 0.57161186 |
102 | AKT2 | 0.56800808 |
103 | PRKACA | 0.56718845 |
104 | PRKAA2 | 0.56573732 |
105 | NTRK2 | 0.55591274 |
106 | SGK2 | 0.55398295 |
107 | DAPK1 | 0.54587536 |
108 | CHEK2 | 0.53879916 |
109 | CAMK4 | 0.52646169 |
110 | CDK8 | 0.52615348 |
111 | PTK2B | 0.51064190 |
112 | PBK | 0.49871959 |
113 | GRK5 | 0.48481447 |
114 | DAPK2 | 0.47916737 |
115 | TAF1 | 0.47673055 |
116 | RPS6KA5 | 0.47639600 |
117 | CSNK1E | 0.47591166 |
118 | LATS1 | 0.47547130 |
119 | STK3 | 0.46554046 |
120 | ATR | 0.46308859 |
121 | MST4 | 0.46143901 |
122 | PRKACB | 0.45384488 |
123 | MKNK2 | 0.45168478 |
124 | ATM | 0.45085450 |
125 | CAMK1D | 0.43363094 |
126 | CDK5 | 0.43362909 |
127 | MAP2K1 | 0.41656149 |
128 | BRSK1 | 0.41202726 |
129 | RAF1 | 0.40536751 |
130 | SRPK1 | 0.40425719 |
131 | ROCK1 | 0.40030928 |
132 | INSRR | 0.39953918 |
133 | CAMK1 | 0.37903227 |
134 | PLK3 | 0.37465807 |
135 | SGK1 | 0.35807237 |
136 | EIF2AK2 | 0.34674375 |
137 | DAPK3 | 0.32131402 |
138 | PRKD1 | 0.31344065 |
139 | CDK3 | 0.31183110 |
140 | CSNK1G2 | 0.29867349 |
141 | DYRK1A | 0.28190891 |
142 | ADRBK1 | 0.27572399 |
143 | CDK18 | 0.27449662 |
144 | AURKA | 0.23745718 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 4.65100246 |
2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 4.06285017 |
3 | Parkinsons disease_Homo sapiens_hsa05012 | 3.44429093 |
4 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 3.39207515 |
5 | Propanoate metabolism_Homo sapiens_hsa00640 | 3.35704440 |
6 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.88375286 |
7 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.81064310 |
8 | Alzheimers disease_Homo sapiens_hsa05010 | 2.63654921 |
9 | Pyruvate metabolism_Homo sapiens_hsa00620 | 2.57236203 |
10 | Huntingtons disease_Homo sapiens_hsa05016 | 2.47656508 |
11 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 2.40417147 |
12 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 2.39845003 |
13 | Fatty acid degradation_Homo sapiens_hsa00071 | 2.19265207 |
14 | Butanoate metabolism_Homo sapiens_hsa00650 | 2.18499621 |
15 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 2.17280798 |
16 | Carbon metabolism_Homo sapiens_hsa01200 | 2.11356816 |
17 | Fatty acid metabolism_Homo sapiens_hsa01212 | 2.06796545 |
18 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.04087040 |
19 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.98163703 |
20 | Protein export_Homo sapiens_hsa03060 | 1.84511961 |
21 | Nicotine addiction_Homo sapiens_hsa05033 | 1.78307712 |
22 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.51255150 |
23 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.50368598 |
24 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 1.45129944 |
25 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.44584345 |
26 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.41928102 |
27 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.34782580 |
28 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.34514019 |
29 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 1.34402455 |
30 | Mismatch repair_Homo sapiens_hsa03430 | 1.32267022 |
31 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 1.31312432 |
32 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.28704769 |
33 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 1.24744640 |
34 | RNA degradation_Homo sapiens_hsa03018 | 1.20162399 |
35 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.19961081 |
36 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.19378979 |
37 | Peroxisome_Homo sapiens_hsa04146 | 1.17875159 |
38 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 1.15467275 |
39 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.15356479 |
40 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.13366572 |
41 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 1.13192280 |
42 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 1.11410080 |
43 | Homologous recombination_Homo sapiens_hsa03440 | 1.10631142 |
44 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.09400269 |
45 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.06861998 |
46 | RNA transport_Homo sapiens_hsa03013 | 1.03151677 |
47 | Proteasome_Homo sapiens_hsa03050 | 1.02523291 |
48 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.99015690 |
49 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.98060775 |
50 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.95548313 |
51 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.91340980 |
52 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.90169229 |
53 | DNA replication_Homo sapiens_hsa03030 | 0.88681400 |
54 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.82782991 |
55 | GABAergic synapse_Homo sapiens_hsa04727 | 0.80828859 |
56 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.80202252 |
57 | Morphine addiction_Homo sapiens_hsa05032 | 0.79822727 |
58 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.79753084 |
59 | Taste transduction_Homo sapiens_hsa04742 | 0.78134431 |
60 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.77413442 |
61 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.76918045 |
62 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.76390752 |
63 | Circadian entrainment_Homo sapiens_hsa04713 | 0.74471039 |
64 | * Metabolic pathways_Homo sapiens_hsa01100 | 0.74172189 |
65 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.73726484 |
66 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.71723676 |
67 | RNA polymerase_Homo sapiens_hsa03020 | 0.68579510 |
68 | Ribosome_Homo sapiens_hsa03010 | 0.66358839 |
69 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.62890717 |
70 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.60701742 |
71 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.58757604 |
72 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.56851976 |
73 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.56471554 |
74 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.56190464 |
75 | Circadian rhythm_Homo sapiens_hsa04710 | 0.55474936 |
76 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.53774103 |
77 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.53765415 |
78 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.53470373 |
79 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.53245295 |
80 | Spliceosome_Homo sapiens_hsa03040 | 0.51571533 |
81 | Long-term potentiation_Homo sapiens_hsa04720 | 0.51386816 |
82 | Olfactory transduction_Homo sapiens_hsa04740 | 0.51080525 |
83 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.50512926 |
84 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.50429618 |
85 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.49584857 |
86 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.49269103 |
87 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.47785675 |
88 | Phototransduction_Homo sapiens_hsa04744 | 0.47697837 |
89 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.47480781 |
90 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.45659755 |
91 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.44807520 |
92 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.44075049 |
93 | Base excision repair_Homo sapiens_hsa03410 | 0.42635283 |
94 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.42415359 |
95 | Renin secretion_Homo sapiens_hsa04924 | 0.41679290 |
96 | Purine metabolism_Homo sapiens_hsa00230 | 0.41138539 |
97 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.39948177 |
98 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.38688615 |
99 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.37324533 |
100 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.37306385 |
101 | Basal transcription factors_Homo sapiens_hsa03022 | 0.36275511 |
102 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.35905661 |
103 | Salivary secretion_Homo sapiens_hsa04970 | 0.34949908 |
104 | Cell cycle_Homo sapiens_hsa04110 | 0.34645335 |
105 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.33117526 |
106 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.31118384 |
107 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.29980752 |
108 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.29945595 |
109 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.29803259 |
110 | Mineral absorption_Homo sapiens_hsa04978 | 0.29510930 |
111 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.29185158 |
112 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.29093320 |
113 | Long-term depression_Homo sapiens_hsa04730 | 0.28058870 |
114 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.26989723 |
115 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.26878666 |
116 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.25669044 |
117 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.25147526 |
118 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.25044687 |
119 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.25010747 |
120 | Insulin secretion_Homo sapiens_hsa04911 | 0.24836990 |
121 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.24755270 |
122 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.24104903 |
123 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.23649300 |
124 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.23629810 |
125 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.22515167 |
126 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.21629494 |
127 | Sulfur relay system_Homo sapiens_hsa04122 | 0.21451042 |