

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | positive regulation of RNA splicing (GO:0033120) | 9.61764901 |
| 2 | seminiferous tubule development (GO:0072520) | 9.54567923 |
| 3 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 9.13863328 |
| 4 | cAMP biosynthetic process (GO:0006171) | 8.80125205 |
| 5 | detection of chemical stimulus involved in sensory perception (GO:0050907) | 8.65715055 |
| 6 | negative regulation of alpha-beta T cell differentiation (GO:0046639) | 8.31932769 |
| 7 | enteric nervous system development (GO:0048484) | 7.80706270 |
| 8 | regulation of protein sumoylation (GO:0033233) | 7.47116488 |
| 9 | positive regulation of mitochondrial fission (GO:0090141) | 7.02154596 |
| 10 | synaptic transmission, dopaminergic (GO:0001963) | 6.97906150 |
| 11 | righting reflex (GO:0060013) | 6.92298336 |
| 12 | dendritic spine morphogenesis (GO:0060997) | 6.82705256 |
| 13 | heterotypic cell-cell adhesion (GO:0034113) | 6.54640101 |
| 14 | positive regulation of T-helper 1 type immune response (GO:0002827) | 6.33478581 |
| 15 | detection of chemical stimulus (GO:0009593) | 6.22041158 |
| 16 | hepatocyte apoptotic process (GO:0097284) | 6.10131047 |
| 17 | icosanoid secretion (GO:0032309) | 6.04677271 |
| 18 | arachidonic acid secretion (GO:0050482) | 6.04677271 |
| 19 | endothelial cell differentiation (GO:0045446) | 5.86330285 |
| 20 | positive regulation of T-helper cell differentiation (GO:0045624) | 5.81939084 |
| 21 | drug transmembrane transport (GO:0006855) | 5.71280705 |
| 22 | phosphatidylinositol acyl-chain remodeling (GO:0036149) | 5.55819391 |
| 23 | phosphatidylserine acyl-chain remodeling (GO:0036150) | 5.15545482 |
| 24 | regulation of mitochondrial fission (GO:0090140) | 5.15287652 |
| 25 | icosanoid transport (GO:0071715) | 5.07270874 |
| 26 | fatty acid derivative transport (GO:1901571) | 5.07270874 |
| 27 | phosphatidylglycerol acyl-chain remodeling (GO:0036148) | 5.04021509 |
| 28 | neuronal ion channel clustering (GO:0045161) | 4.88844429 |
| 29 | negative regulation of alpha-beta T cell activation (GO:0046636) | 4.83187438 |
| 30 | hyaluronan catabolic process (GO:0030214) | 4.73665101 |
| 31 | chemosensory behavior (GO:0007635) | 4.72913197 |
| 32 | cilium or flagellum-dependent cell motility (GO:0001539) | 4.71443917 |
| 33 | neural tube formation (GO:0001841) | 4.71307643 |
| 34 | regulation of T-helper 1 type immune response (GO:0002825) | 4.56769937 |
| 35 | nephron epithelium morphogenesis (GO:0072088) | 4.45912189 |
| 36 | nephron tubule morphogenesis (GO:0072078) | 4.45912189 |
| 37 | positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372) | 4.44303835 |
| 38 | embryonic digestive tract morphogenesis (GO:0048557) | 4.43144334 |
| 39 | cyclic purine nucleotide metabolic process (GO:0052652) | 4.40320970 |
| 40 | ATP hydrolysis coupled proton transport (GO:0015991) | 4.37067450 |
| 41 | energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988) | 4.37067450 |
| 42 | cyclic nucleotide biosynthetic process (GO:0009190) | 4.28334007 |
| 43 | attachment of spindle microtubules to kinetochore (GO:0008608) | 4.26877601 |
| 44 | negative regulation of actin filament bundle assembly (GO:0032232) | 4.25855173 |
| 45 | retina layer formation (GO:0010842) | 4.25369182 |
| 46 | regulation of T-helper cell differentiation (GO:0045622) | 4.22803757 |
| 47 | regulation of type 2 immune response (GO:0002828) | 4.22753910 |
| 48 | positive regulation of membrane potential (GO:0045838) | 4.19746915 |
| 49 | vocalization behavior (GO:0071625) | 4.19003643 |
| 50 | cellular response to glucagon stimulus (GO:0071377) | 4.16286816 |
| 51 | regulation of cAMP-mediated signaling (GO:0043949) | 4.13537854 |
| 52 | response to dietary excess (GO:0002021) | 4.08039816 |
| 53 | mitochondrial fusion (GO:0008053) | 4.03359758 |
| 54 | water transport (GO:0006833) | 4.02618330 |
| 55 | cAMP metabolic process (GO:0046058) | 4.00590197 |
| 56 | drug transport (GO:0015893) | 3.92297576 |
| 57 | positive regulation of CD4-positive, alpha-beta T cell activation (GO:2000516) | 3.90754029 |
| 58 | dendritic spine organization (GO:0097061) | 3.90374420 |
| 59 | protein localization to synapse (GO:0035418) | 3.83589323 |
| 60 | cytoskeletal anchoring at plasma membrane (GO:0007016) | 3.82558667 |
| 61 | negative regulation of cytosolic calcium ion concentration (GO:0051481) | 3.79011170 |
| 62 | monoamine transport (GO:0015844) | 3.75106111 |
| 63 | negative regulation of T cell differentiation (GO:0045581) | 3.71108669 |
| 64 | cellular zinc ion homeostasis (GO:0006882) | 3.70690563 |
| 65 | phosphatidylethanolamine acyl-chain remodeling (GO:0036152) | 3.65256048 |
| 66 | fluid transport (GO:0042044) | 3.59977145 |
| 67 | leukotriene biosynthetic process (GO:0019370) | 3.57048391 |
| 68 | cellular response to ATP (GO:0071318) | 3.56162423 |
| 69 | positive regulation of protein targeting to membrane (GO:0090314) | 3.51881300 |
| 70 | sulfur amino acid catabolic process (GO:0000098) | 3.45400408 |
| 71 | sequestering of metal ion (GO:0051238) | 3.40491691 |
| 72 | negative regulation of homotypic cell-cell adhesion (GO:0034111) | 3.37557997 |
| 73 | positive regulation of alpha-beta T cell differentiation (GO:0046638) | 3.34474146 |
| 74 | pre-miRNA processing (GO:0031054) | 3.34284446 |
| 75 | regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043370) | 3.33717554 |
| 76 | positive regulation of extrinsic apoptotic signaling pathway via death domain receptors (GO:1902043) | 3.32379022 |
| 77 | left/right axis specification (GO:0070986) | 3.26267644 |
| 78 | renal tubule morphogenesis (GO:0061333) | 3.21918704 |
| 79 | phosphatidylcholine acyl-chain remodeling (GO:0036151) | 3.15472804 |
| 80 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.14503127 |
| 81 | negative regulation of hydrogen peroxide-induced cell death (GO:1903206) | 3.12645231 |
| 82 | response to glucagon (GO:0033762) | 3.08237465 |
| 83 | neuromuscular process controlling posture (GO:0050884) | 3.06623896 |
| 84 | negative regulation of astrocyte differentiation (GO:0048712) | 3.05881661 |
| 85 | adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway (GO:0007193) | 3.00665069 |
| 86 | positive regulation of steroid hormone secretion (GO:2000833) | 3.00587046 |
| 87 | reflex (GO:0060004) | 2.99853955 |
| 88 | adenylate cyclase-activating G-protein coupled receptor signaling pathway (GO:0007189) | 2.99583868 |
| 89 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 2.99485444 |
| 90 | neurofilament cytoskeleton organization (GO:0060052) | 2.99393603 |
| 91 | tooth mineralization (GO:0034505) | 14.8292921 |
| 92 | detection of chemical stimulus involved in sensory perception of smell (GO:0050911) | 13.9142327 |
| 93 | positive regulation of protein sumoylation (GO:0033235) | 11.8884459 |
| 94 | negative regulation of T-helper cell differentiation (GO:0045623) | 11.3758342 |
| 95 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 11.3758342 |
| 96 | protein K11-linked deubiquitination (GO:0035871) | 10.5693584 |
| 97 | regulation of T-helper 1 cell differentiation (GO:0045625) | 10.2922524 |
| 98 | regulation of T-helper 2 cell differentiation (GO:0045628) | 10.1026510 |
| 99 | negative regulation of type 2 immune response (GO:0002829) | 10.0072585 |
| 100 | activation of protein kinase A activity (GO:0034199) | 10.0066654 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 6.57250315 |
| 2 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 5.58467600 |
| 3 | IGF1R_20145208_ChIP-Seq_DFB_Human | 4.81395124 |
| 4 | AR_21572438_ChIP-Seq_LNCaP_Human | 4.73027932 |
| 5 | VDR_22108803_ChIP-Seq_LS180_Human | 4.23406390 |
| 6 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 3.41997597 |
| 7 | TP53_16413492_ChIP-PET_HCT116_Human | 2.09377450 |
| 8 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 2.01442205 |
| 9 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 10.7846051 |
| 10 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 1.95629096 |
| 11 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.89002628 |
| 12 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.88195339 |
| 13 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.88195339 |
| 14 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.83319555 |
| 15 | GATA1_19941826_ChIP-Seq_K562_Human | 1.81763399 |
| 16 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.67483611 |
| 17 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.66316383 |
| 18 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 1.61920008 |
| 19 | EGR1_19032775_ChIP-ChIP_M12_Human | 1.59927342 |
| 20 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.54745943 |
| 21 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.50652071 |
| 22 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.46153352 |
| 23 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.46046345 |
| 24 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 1.44779787 |
| 25 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.40351415 |
| 26 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.38722917 |
| 27 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.35494598 |
| 28 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.32830058 |
| 29 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.31812710 |
| 30 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.30193975 |
| 31 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.30157805 |
| 32 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.27407180 |
| 33 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.26660850 |
| 34 | TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.25421980 |
| 35 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.21203269 |
| 36 | RXR_22108803_ChIP-Seq_LS180_Human | 1.18804152 |
| 37 | CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse | 1.14020035 |
| 38 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.13929964 |
| 39 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.12014413 |
| 40 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.11181215 |
| 41 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.09183385 |
| 42 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 1.08486737 |
| 43 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.07821271 |
| 44 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 1.07784329 |
| 45 | HNFA_21074721_ChIP-Seq_CACO-2_Human | 1.06849457 |
| 46 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.04465090 |
| 47 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.04444062 |
| 48 | SOX2_18555785_Chip-Seq_ESCs_Mouse | 1.03428502 |
| 49 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.03101725 |
| 50 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 1.02666889 |
| 51 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.02612592 |
| 52 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.02537331 |
| 53 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.01942335 |
| 54 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 1.00192199 |
| 55 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 0.99846861 |
| 56 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 0.99213593 |
| 57 | GBX2_23144817_ChIP-Seq_PC3_Human | 0.98526900 |
| 58 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 0.97837473 |
| 59 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 0.97645096 |
| 60 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.97568028 |
| 61 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 0.96555903 |
| 62 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 0.96403649 |
| 63 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 0.96398084 |
| 64 | SMAD4_21741376_ChIP-Seq_HESCs_Human | 0.95104935 |
| 65 | TBL1_22424771_ChIP-Seq_293T_Human | 0.94856197 |
| 66 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 0.94285013 |
| 67 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 0.94146825 |
| 68 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 0.94052369 |
| 69 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 0.91106700 |
| 70 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.90884793 |
| 71 | PHF8_20622853_ChIP-Seq_HELA_Human | 0.90618995 |
| 72 | STAT3_23295773_ChIP-Seq_U87_Human | 0.89879764 |
| 73 | CJUN_26792858_Chip-Seq_BT549_Human | 0.88904900 |
| 74 | CDX2_21074721_ChIP-Seq_CACO-2_Mouse | 0.86615868 |
| 75 | NANOG_16518401_ChIP-PET_MESCs_Mouse | 0.86270316 |
| 76 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.85704228 |
| 77 | GATA3_20176728_ChIP-ChIP_TSCs_Mouse | 0.85696999 |
| 78 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 0.85168516 |
| 79 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 0.85140239 |
| 80 | CTCF_27219007_Chip-Seq_Bcells_Human | 0.85104372 |
| 81 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 0.84654118 |
| 82 | SUZ12_18555785_Chip-Seq_ESCs_Mouse | 0.83466880 |
| 83 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.83148811 |
| 84 | PCGF4_22325352_ChIP-Seq_293T-Rex_Human | 0.83013559 |
| 85 | ZNF274_21170338_ChIP-Seq_K562_Hela | 0.82646786 |
| 86 | KLF4_18555785_Chip-Seq_ESCs_Mouse | 0.81319356 |
| 87 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 0.81205213 |
| 88 | NMYC_18555785_Chip-Seq_ESCs_Mouse | 0.81111450 |
| 89 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 0.80384604 |
| 90 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 0.78232889 |
| 91 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 0.78130944 |
| 92 | GATA2_19941826_ChIP-Seq_K562_Human | 0.77746098 |
| 93 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.77293591 |
| 94 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 0.76376062 |
| 95 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 0.76376062 |
| 96 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 0.76024931 |
| 97 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.75304942 |
| 98 | REST_21632747_ChIP-Seq_MESCs_Mouse | 0.75220447 |
| 99 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 0.74449547 |
| 100 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 0.74259051 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0008961_abnormal_basal_metabolism | 9.57630752 |
| 2 | MP0004130_abnormal_muscle_cell | 5.08239005 |
| 3 | MP0004264_abnormal_extraembryonic_tissu | 3.99036694 |
| 4 | MP0003252_abnormal_bile_duct | 3.63684035 |
| 5 | MP0004133_heterotaxia | 2.76295671 |
| 6 | MP0002928_abnormal_bile_duct | 2.68040369 |
| 7 | MP0006072_abnormal_retinal_apoptosis | 2.31068522 |
| 8 | MP0005448_abnormal_energy_balance | 2.29935558 |
| 9 | MP0003329_amyloid_beta_deposits | 2.24008580 |
| 10 | MP0005408_hypopigmentation | 2.21269192 |
| 11 | MP0002751_abnormal_autonomic_nervous | 2.13057515 |
| 12 | MP0001270_distended_abdomen | 2.11056939 |
| 13 | MP0004272_abnormal_basement_membrane | 2.10535738 |
| 14 | MP0005084_abnormal_gallbladder_morpholo | 12.6941674 |
| 15 | MP0005379_endocrine/exocrine_gland_phen | 1.72819813 |
| 16 | MP0003943_abnormal_hepatobiliary_system | 1.68538081 |
| 17 | MP0005220_abnormal_exocrine_pancreas | 1.60537843 |
| 18 | MP0005165_increased_susceptibility_to | 1.60498976 |
| 19 | MP0009764_decreased_sensitivity_to | 1.53099062 |
| 20 | MP0000604_amyloidosis | 1.42583219 |
| 21 | MP0001958_emphysema | 1.41160621 |
| 22 | MP0003718_maternal_effect | 1.32324790 |
| 23 | MP0001529_abnormal_vocalization | 1.27194362 |
| 24 | MP0000470_abnormal_stomach_morphology | 1.04712260 |
| 25 | MP0005646_abnormal_pituitary_gland | 1.02794997 |
| 26 | MP0001905_abnormal_dopamine_level | 1.01095622 |
| 27 | MP0000465_gastrointestinal_hemorrhage | 0.99782240 |
| 28 | MP0002909_abnormal_adrenal_gland | 0.97847921 |
| 29 | MP0002572_abnormal_emotion/affect_behav | 0.93732803 |
| 30 | MP0003638_abnormal_response/metabolism_ | 0.93675519 |
| 31 | MP0001944_abnormal_pancreas_morphology | 0.91094486 |
| 32 | MP0008569_lethality_at_weaning | 0.89393768 |
| 33 | MP0001800_abnormal_humoral_immune | 0.85910761 |
| 34 | MP0005164_abnormal_response_to | 0.81118839 |
| 35 | MP0001915_intracranial_hemorrhage | 0.80961494 |
| 36 | MP0008469_abnormal_protein_level | 0.80890923 |
| 37 | MP0008875_abnormal_xenobiotic_pharmacok | 0.80668464 |
| 38 | MP0004019_abnormal_vitamin_homeostasis | 0.78359762 |
| 39 | MP0003866_abnormal_defecation | 0.76894037 |
| 40 | MP0000371_diluted_coat_color | 0.75266383 |
| 41 | MP0001790_abnormal_immune_system | 0.74935709 |
| 42 | MP0005387_immune_system_phenotype | 0.74935709 |
| 43 | MP0002405_respiratory_system_inflammati | 0.73771226 |
| 44 | MP0002693_abnormal_pancreas_physiology | 0.72918974 |
| 45 | MP0000609_abnormal_liver_physiology | 0.72664318 |
| 46 | MP0002098_abnormal_vibrissa_morphology | 0.70086842 |
| 47 | MP0003121_genomic_imprinting | 0.68652648 |
| 48 | MP0001533_abnormal_skeleton_physiology | 0.67437261 |
| 49 | MP0004947_skin_inflammation | 0.65669514 |
| 50 | MP0002136_abnormal_kidney_physiology | 0.65446371 |
| 51 | MP0001851_eye_inflammation | 0.63638849 |
| 52 | MP0000703_abnormal_thymus_morphology | 0.62916064 |
| 53 | MP0002078_abnormal_glucose_homeostasis | 0.61525818 |
| 54 | MP0003953_abnormal_hormone_level | 0.60809670 |
| 55 | MP0005253_abnormal_eye_physiology | 0.59016262 |
| 56 | MP0002998_abnormal_bone_remodeling | 0.54677571 |
| 57 | MP0001845_abnormal_inflammatory_respons | 0.54185866 |
| 58 | MP0009642_abnormal_blood_homeostasis | 0.48057525 |
| 59 | MP0002722_abnormal_immune_system | 0.47241784 |
| 60 | MP0003195_calcinosis | 0.46694187 |
| 61 | MP0001835_abnormal_antigen_presentation | 0.44914185 |
| 62 | MP0002419_abnormal_innate_immunity | 0.44814874 |
| 63 | MP0005365_abnormal_bile_salt | 0.44426699 |
| 64 | MP0002452_abnormal_antigen_presenting | 0.42975540 |
| 65 | MP0005551_abnormal_eye_electrophysiolog | 0.41896651 |
| 66 | MP0002429_abnormal_blood_cell | 0.41715537 |
| 67 | MP0008004_abnormal_stomach_pH | 0.40491768 |
| 68 | MP0004484_altered_response_of | 0.40439393 |
| 69 | MP0002420_abnormal_adaptive_immunity | 0.38135157 |
| 70 | MP0001819_abnormal_immune_cell | 0.37335930 |
| 71 | MP0005334_abnormal_fat_pad | 0.36809427 |
| 72 | MP0000598_abnormal_liver_morphology | 0.36356508 |
| 73 | MP0000477_abnormal_intestine_morphology | 0.35557641 |
| 74 | MP0000716_abnormal_immune_system | 0.35417618 |
| 75 | MP0002723_abnormal_immune_serum | 0.35319978 |
| 76 | MP0005390_skeleton_phenotype | 0.35130350 |
| 77 | MP0009931_abnormal_skin_appearance | 0.34715340 |
| 78 | MP0001986_abnormal_taste_sensitivity | 0.34208262 |
| 79 | MP0001501_abnormal_sleep_pattern | 0.33656857 |
| 80 | MP0002398_abnormal_bone_marrow | 0.33144298 |
| 81 | MP0000759_abnormal_skeletal_muscle | 0.33099760 |
| 82 | MP0000920_abnormal_myelination | 0.32628548 |
| 83 | MP0005000_abnormal_immune_tolerance | 0.31444334 |
| 84 | MP0005395_other_phenotype | 0.30602628 |
| 85 | MP0002229_neurodegeneration | 0.28982327 |
| 86 | MP0002822_catalepsy | 0.28585325 |
| 87 | MP0002882_abnormal_neuron_morphology | 0.28205395 |
| 88 | MP0000689_abnormal_spleen_morphology | 0.27474131 |
| 89 | MP0001299_abnormal_eye_distance/ | 0.27455285 |
| 90 | MP0001175_abnormal_lung_morphology | 0.26855789 |
| 91 | MP0005423_abnormal_somatic_nervous | 0.26644959 |
| 92 | MP0005645_abnormal_hypothalamus_physiol | 0.26443107 |
| 93 | MP0002735_abnormal_chemical_nociception | 0.25017319 |
| 94 | MP0002139_abnormal_hepatobiliary_system | 0.24540272 |
| 95 | MP0000249_abnormal_blood_vessel | 0.24224719 |
| 96 | MP0002837_dystrophic_cardiac_calcinosis | 0.22237642 |
| 97 | MP0005332_abnormal_amino_acid | 0.22050865 |
| 98 | MP0009053_abnormal_anal_canal | 0.21579696 |
| 99 | MP0003646_muscle_fatigue | 0.21088052 |
| 100 | MP0002161_abnormal_fertility/fecundity | 0.20957266 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Abnormality of calcium-phosphate metabolism (HP:0100530) | 9.93474366 |
| 2 | Abnormality of dental color (HP:0011073) | 8.29211767 |
| 3 | Abnormality of renal resorption (HP:0011038) | 8.16387155 |
| 4 | Osteomalacia (HP:0002749) | 7.79057489 |
| 5 | Polyuria (HP:0000103) | 7.65636236 |
| 6 | Abnormality of the dental pulp (HP:0006479) | 7.52467497 |
| 7 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 6.74457250 |
| 8 | Abnormal urine output (HP:0012590) | 6.55310431 |
| 9 | Abnormality of renal excretion (HP:0011036) | 5.73592596 |
| 10 | Round ear (HP:0100830) | 5.56372598 |
| 11 | Chronic bronchitis (HP:0004469) | 4.89317731 |
| 12 | Autoimmune thrombocytopenia (HP:0001973) | 4.20845941 |
| 13 | IgM deficiency (HP:0002850) | 4.18864001 |
| 14 | Volvulus (HP:0002580) | 4.14882596 |
| 15 | Lip pit (HP:0100267) | 4.08253196 |
| 16 | Toxemia of pregnancy (HP:0100603) | 4.04994546 |
| 17 | Nephrocalcinosis (HP:0000121) | 4.02126176 |
| 18 | Abnormality of midbrain morphology (HP:0002418) | 3.90953848 |
| 19 | Molar tooth sign on MRI (HP:0002419) | 3.90953848 |
| 20 | Esophageal varix (HP:0002040) | 3.81892548 |
| 21 | Lipoatrophy (HP:0100578) | 3.41374458 |
| 22 | Tachypnea (HP:0002789) | 3.29170924 |
| 23 | Depressed nasal tip (HP:0000437) | 3.28101642 |
| 24 | Rhinitis (HP:0012384) | 3.27914637 |
| 25 | Large earlobe (HP:0009748) | 3.27415620 |
| 26 | Abnormal respiratory motile cilium physiology (HP:0012261) | 3.26527156 |
| 27 | Sparse lateral eyebrow (HP:0005338) | 3.20944739 |
| 28 | Panhypogammaglobulinemia (HP:0003139) | 3.18611307 |
| 29 | Drooling (HP:0002307) | 3.07456127 |
| 30 | Hypoparathyroidism (HP:0000829) | 3.06705231 |
| 31 | Intestinal fistula (HP:0100819) | 3.03355699 |
| 32 | Excessive salivation (HP:0003781) | 2.95474112 |
| 33 | Hyperphosphaturia (HP:0003109) | 2.91448257 |
| 34 | Petechiae (HP:0000967) | 2.80847884 |
| 35 | Personality changes (HP:0000751) | 2.74222795 |
| 36 | Thick eyebrow (HP:0000574) | 2.72783371 |
| 37 | Hepatitis (HP:0012115) | 2.71454158 |
| 38 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 2.68892720 |
| 39 | Nephronophthisis (HP:0000090) | 2.68342725 |
| 40 | Abnormality of transition element cation homeostasis (HP:0011030) | 2.62029784 |
| 41 | Ureteral stenosis (HP:0000071) | 2.59306229 |
| 42 | Dilated cardiomyopathy (HP:0001644) | 2.50509672 |
| 43 | Abnormality of urine glucose concentration (HP:0011016) | 2.44793240 |
| 44 | Glycosuria (HP:0003076) | 2.44793240 |
| 45 | Abnormal urine phosphate concentration (HP:0012599) | 2.43274734 |
| 46 | Inability to walk (HP:0002540) | 2.43075026 |
| 47 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.40897142 |
| 48 | Recurrent cutaneous fungal infections (HP:0011370) | 2.40897142 |
| 49 | Short 5th finger (HP:0009237) | 2.37962353 |
| 50 | Ureteral obstruction (HP:0006000) | 2.37660532 |
| 51 | Striae distensae (HP:0001065) | 2.33572798 |
| 52 | Nephropathy (HP:0000112) | 2.31890721 |
| 53 | Sudden cardiac death (HP:0001645) | 2.31660619 |
| 54 | Gingival overgrowth (HP:0000212) | 2.29809894 |
| 55 | Abnormality of the fingertips (HP:0001211) | 2.28538007 |
| 56 | Colitis (HP:0002583) | 2.27179285 |
| 57 | Aplasia/Hypoplasia of the 5th finger (HP:0006262) | 2.26941092 |
| 58 | Hypercalciuria (HP:0002150) | 2.24694500 |
| 59 | Agammaglobulinemia (HP:0004432) | 2.22182364 |
| 60 | Decreased muscle mass (HP:0003199) | 2.18178438 |
| 61 | Bronchitis (HP:0012387) | 2.13064532 |
| 62 | Periauricular skin pits (HP:0100277) | 2.09928426 |
| 63 | Preauricular pit (HP:0004467) | 2.09928426 |
| 64 | Recurrent otitis media (HP:0000403) | 2.09050609 |
| 65 | Abnormality of the renal medulla (HP:0100957) | 2.00316852 |
| 66 | Overgrowth (HP:0001548) | 12.0656696 |
| 67 | Amelogenesis imperfecta (HP:0000705) | 11.7250176 |
| 68 | Chondrocalcinosis (HP:0000934) | 1.99680515 |
| 69 | Anal stenosis (HP:0002025) | 1.97402247 |
| 70 | Renal tubular dysfunction (HP:0000124) | 1.97154326 |
| 71 | Abnormality of salivation (HP:0100755) | 1.97094850 |
| 72 | Abnormality of Sharpey fibers (HP:0100685) | 1.94558861 |
| 73 | Delayed eruption of teeth (HP:0000684) | 1.91780855 |
| 74 | Chorioretinal coloboma (HP:0000567) | 1.84718371 |
| 75 | Ectopic kidney (HP:0000086) | 1.83908903 |
| 76 | Prominent supraorbital ridges (HP:0000336) | 1.79211161 |
| 77 | Stage 5 chronic kidney disease (HP:0003774) | 1.77749010 |
| 78 | Preauricular skin tag (HP:0000384) | 1.73900986 |
| 79 | Small hand (HP:0200055) | 1.70010599 |
| 80 | Limited elbow extension (HP:0001377) | 1.69706830 |
| 81 | Truncal ataxia (HP:0002078) | 1.67796273 |
| 82 | Abnormality of small intestinal villus morphology (HP:0011472) | 1.65545585 |
| 83 | Villous atrophy (HP:0011473) | 1.65545585 |
| 84 | Oculomotor apraxia (HP:0000657) | 1.63058185 |
| 85 | Palmoplantar keratoderma (HP:0000982) | 1.60623170 |
| 86 | Viral hepatitis (HP:0006562) | 1.57267828 |
| 87 | Torticollis (HP:0000473) | 1.54760905 |
| 88 | Ectropion (HP:0000656) | 1.54537953 |
| 89 | Blepharitis (HP:0000498) | 1.53222072 |
| 90 | Polyneuropathy (HP:0001271) | 1.53109128 |
| 91 | Bronchiectasis (HP:0002110) | 1.48025923 |
| 92 | Prenatal maternal abnormality (HP:0002686) | 1.46263919 |
| 93 | Skin tags (HP:0010609) | 1.45114431 |
| 94 | Skin pits (HP:0100276) | 1.39505882 |
| 95 | Inflammation of the large intestine (HP:0002037) | 1.39407187 |
| 96 | Highly arched eyebrow (HP:0002553) | 1.38301132 |
| 97 | Osteoarthritis (HP:0002758) | 1.34800421 |
| 98 | Proximal placement of thumb (HP:0009623) | 1.29533970 |
| 99 | Mask-like facies (HP:0000298) | 1.28992609 |
| 100 | Aplasia/Hypoplasia of the fovea (HP:0008060) | 1.28314425 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MAP4K1 | 5.63134717 |
| 2 | BLK | 4.31764065 |
| 3 | STK3 | 4.12142063 |
| 4 | RIPK4 | 3.82663164 |
| 5 | BMPR2 | 2.47243538 |
| 6 | CDC42BPA | 2.14934742 |
| 7 | NTRK2 | 13.9619363 |
| 8 | HIPK2 | 1.24028223 |
| 9 | TIE1 | 0.94444943 |
| 10 | FGFR1 | 0.82638052 |
| 11 | SYK | 0.76631130 |
| 12 | ROCK2 | 0.75156394 |
| 13 | TLK1 | 0.65730631 |
| 14 | SRC | 0.61687375 |
| 15 | INSRR | 0.61148650 |
| 16 | PRKCQ | 0.60587385 |
| 17 | PRKAA1 | 0.60138615 |
| 18 | GRK1 | 0.60055672 |
| 19 | OBSCN | 0.56217427 |
| 20 | MAP4K2 | 0.52756911 |
| 21 | ROCK1 | 0.51848371 |
| 22 | MUSK | 0.51445194 |
| 23 | ADRBK2 | 0.49785670 |
| 24 | GRK7 | 0.44886254 |
| 25 | PRKACG | 0.44715062 |
| 26 | TXK | 0.44221937 |
| 27 | WNK3 | 0.42276692 |
| 28 | ABL1 | 0.40973179 |
| 29 | PLK4 | 0.35140863 |
| 30 | PRKACA | 0.34856888 |
| 31 | MAPK15 | 0.34768642 |
| 32 | CAMK2A | 0.32310963 |
| 33 | PRKACB | 0.32097422 |
| 34 | PIK3CG | 0.30537855 |
| 35 | GRK5 | 0.28486932 |
| 36 | TEC | 0.28367346 |
| 37 | KIT | 0.27400588 |
| 38 | PLK1 | 0.27008689 |
| 39 | LYN | 0.25504824 |
| 40 | ERBB4 | 0.25457857 |
| 41 | MATK | 0.25425691 |
| 42 | PINK1 | 0.24617022 |
| 43 | SRPK1 | 0.24429144 |
| 44 | PRKCA | 0.23980438 |
| 45 | KDR | 0.23934945 |
| 46 | LMTK2 | 0.22854346 |
| 47 | PIM2 | 0.21759098 |
| 48 | PHKG2 | 0.21590108 |
| 49 | PHKG1 | 0.21590108 |
| 50 | PRKCB | 0.20568962 |
| 51 | MAPK14 | 0.19579572 |
| 52 | ZAK | 0.19357327 |
| 53 | BTK | 0.19240633 |
| 54 | EPHA2 | 0.18317132 |
| 55 | MST1R | 0.17864426 |
| 56 | GSK3B | 0.17495044 |
| 57 | ERBB2 | 0.15746624 |
| 58 | EPHA4 | 0.15717810 |
| 59 | RPS6KA3 | 0.15674343 |
| 60 | ITK | 0.15617036 |
| 61 | FYN | 0.15211645 |
| 62 | PRKCD | 0.14092892 |
| 63 | MAPKAPK5 | 0.13728234 |
| 64 | CSNK1A1 | 0.13455742 |
| 65 | OXSR1 | 0.13406852 |
| 66 | GRK6 | 0.13338175 |
| 67 | TTN | 0.12567188 |
| 68 | VRK1 | 0.11667540 |
| 69 | DDR2 | 0.11160215 |
| 70 | CDK1 | 0.10990681 |
| 71 | CCNB1 | 0.10822243 |
| 72 | PRKCG | 0.10086097 |
| 73 | IGF1R | 0.09965178 |
| 74 | ADRBK1 | 0.09379849 |
| 75 | PKN1 | 0.08370768 |
| 76 | CHUK | 0.08299716 |
| 77 | MYLK | 0.08229634 |
| 78 | WNK4 | 0.07950240 |
| 79 | HCK | 0.07522903 |
| 80 | LCK | 0.06949097 |
| 81 | MAPK9 | 0.06884843 |
| 82 | CAMK2G | 0.06539368 |
| 83 | EGFR | 0.06280825 |
| 84 | PRKDC | 0.06168560 |
| 85 | MAPK4 | 0.05810685 |
| 86 | TNK2 | 0.04579696 |
| 87 | DAPK3 | 0.04547840 |
| 88 | PIK3CA | 0.04452220 |
| 89 | PIM1 | 0.04423740 |
| 90 | MAP2K6 | 0.04236481 |
| 91 | PRKCE | 0.04114193 |
| 92 | ABL2 | 0.03145958 |
| 93 | TGFBR2 | 0.03101045 |
| 94 | AKT1 | 0.02900782 |
| 95 | FRK | 0.02829781 |
| 96 | MAP3K3 | 0.02649148 |
| 97 | FLT3 | 0.01537062 |
| 98 | PRKG2 | 0.01425919 |
| 99 | PRKG1 | 0.01015301 |
| 100 | CAMK2B | 0.00607141 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Olfactory transduction_Homo sapiens_hsa04740 | 5.43122427 |
| 2 | Sulfur relay system_Homo sapiens_hsa04122 | 3.78702880 |
| 3 | Sulfur metabolism_Homo sapiens_hsa00920 | 3.71306447 |
| 4 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 3.33480056 |
| 5 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 3.20303885 |
| 6 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 2.93434678 |
| 7 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 2.84327226 |
| 8 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 2.68781293 |
| 9 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 2.53820944 |
| 10 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 2.38214549 |
| 11 | Bile secretion_Homo sapiens_hsa04976 | 2.37275972 |
| 12 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 2.23698957 |
| 13 | Pancreatic secretion_Homo sapiens_hsa04972 | 2.20579163 |
| 14 | Salivary secretion_Homo sapiens_hsa04970 | 2.16132676 |
| 15 | Fat digestion and absorption_Homo sapiens_hsa04975 | 2.14971110 |
| 16 | Gastric acid secretion_Homo sapiens_hsa04971 | 2.12355516 |
| 17 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 2.01244586 |
| 18 | Cocaine addiction_Homo sapiens_hsa05030 | 1.88656422 |
| 19 | Circadian entrainment_Homo sapiens_hsa04713 | 1.83063040 |
| 20 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.80353350 |
| 21 | Insulin secretion_Homo sapiens_hsa04911 | 1.77177778 |
| 22 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 1.76134430 |
| 23 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.69869005 |
| 24 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 1.67444679 |
| 25 | Morphine addiction_Homo sapiens_hsa05032 | 1.66640818 |
| 26 | Taste transduction_Homo sapiens_hsa04742 | 1.66393988 |
| 27 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 1.64437711 |
| 28 | GABAergic synapse_Homo sapiens_hsa04727 | 1.64193498 |
| 29 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 1.59656554 |
| 30 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.59311645 |
| 31 | Gap junction_Homo sapiens_hsa04540 | 1.50691277 |
| 32 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 1.50150334 |
| 33 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 1.40731940 |
| 34 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 1.39765989 |
| 35 | Amphetamine addiction_Homo sapiens_hsa05031 | 1.36060810 |
| 36 | GnRH signaling pathway_Homo sapiens_hsa04912 | 1.34062947 |
| 37 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 1.32726930 |
| 38 | Melanogenesis_Homo sapiens_hsa04916 | 1.28623089 |
| 39 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 1.24508935 |
| 40 | Platelet activation_Homo sapiens_hsa04611 | 1.17818704 |
| 41 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 1.16695421 |
| 42 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.09996611 |
| 43 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 1.08169199 |
| 44 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.06760374 |
| 45 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 1.01652082 |
| 46 | Circadian rhythm_Homo sapiens_hsa04710 | 0.98795994 |
| 47 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.85983854 |
| 48 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.83352132 |
| 49 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.75434162 |
| 50 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.74717862 |
| 51 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.73447919 |
| 52 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.71545370 |
| 53 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.70980559 |
| 54 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.59692380 |
| 55 | RNA degradation_Homo sapiens_hsa03018 | 0.57042352 |
| 56 | Alcoholism_Homo sapiens_hsa05034 | 0.44084600 |
| 57 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.44064945 |
| 58 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.41355038 |
| 59 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.41153054 |
| 60 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.40088364 |
| 61 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.37611340 |
| 62 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.35727525 |
| 63 | Parkinsons disease_Homo sapiens_hsa05012 | 0.35440119 |
| 64 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.32770772 |
| 65 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.32004449 |
| 66 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.31358918 |
| 67 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.28749215 |
| 68 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.27203159 |
| 69 | Purine metabolism_Homo sapiens_hsa00230 | 0.25671278 |
| 70 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.25344608 |
| 71 | Retinol metabolism_Homo sapiens_hsa00830 | 0.23042981 |
| 72 | Prion diseases_Homo sapiens_hsa05020 | 0.22905617 |
| 73 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.20135788 |
| 74 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.19923416 |
| 75 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.19387982 |
| 76 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.18975646 |
| 77 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.18676848 |
| 78 | Phagosome_Homo sapiens_hsa04145 | 0.17481278 |
| 79 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.17299026 |
| 80 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.14983245 |
| 81 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.14860426 |
| 82 | Tuberculosis_Homo sapiens_hsa05152 | 0.14779335 |
| 83 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.13922057 |
| 84 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.13483707 |
| 85 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.11206241 |
| 86 | Leishmaniasis_Homo sapiens_hsa05140 | 0.10918961 |
| 87 | Asthma_Homo sapiens_hsa05310 | 0.10871145 |
| 88 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.10554038 |
| 89 | HTLV-I infection_Homo sapiens_hsa05166 | 0.10501612 |
| 90 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.09370764 |
| 91 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.09297426 |
| 92 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.08959210 |
| 93 | Allograft rejection_Homo sapiens_hsa05330 | 0.07632022 |
| 94 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.07499290 |
| 95 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.07106023 |
| 96 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.05983882 |
| 97 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.05732840 |
| 98 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.02978541 |
| 99 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.02368883 |
| 100 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.02198257 |

