Rank | Gene Set | Z-score |
---|---|---|
1 | thyroid hormone metabolic process (GO:0042403) | 7.63656442 |
2 | cellular potassium ion homeostasis (GO:0030007) | 6.10171438 |
3 | modified amino acid transport (GO:0072337) | 6.07284726 |
4 | gamma-aminobutyric acid signaling pathway (GO:0007214) | 5.77543514 |
5 | neurotransmitter uptake (GO:0001504) | 5.47240066 |
6 | regulation of female receptivity (GO:0045924) | 5.24862502 |
7 | sodium ion export (GO:0071436) | 5.23566553 |
8 | female mating behavior (GO:0060180) | 5.17543539 |
9 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 5.04084881 |
10 | synaptic vesicle endocytosis (GO:0048488) | 5.01228607 |
11 | positive regulation of synaptic transmission, dopaminergic (GO:0032226) | 4.96071053 |
12 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 4.90521745 |
13 | vocalization behavior (GO:0071625) | 4.86356292 |
14 | synaptic vesicle maturation (GO:0016188) | 4.77249943 |
15 | synaptic vesicle exocytosis (GO:0016079) | 4.72873248 |
16 | positive regulation of potassium ion transmembrane transporter activity (GO:1901018) | 4.72847243 |
17 | regulation of synaptic vesicle exocytosis (GO:2000300) | 4.66763021 |
18 | response to histamine (GO:0034776) | 4.61644242 |
19 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 4.58816249 |
20 | regulation of glutamate receptor signaling pathway (GO:1900449) | 4.49556203 |
21 | locomotory exploration behavior (GO:0035641) | 4.49404559 |
22 | L-amino acid import (GO:0043092) | 4.47619725 |
23 | positive regulation of synaptic transmission, GABAergic (GO:0032230) | 4.41556013 |
24 | activation of protein kinase A activity (GO:0034199) | 4.40316919 |
25 | striatum development (GO:0021756) | 4.37049532 |
26 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 4.31006817 |
27 | positive regulation of amino acid transport (GO:0051957) | 4.29902657 |
28 | positive regulation of catecholamine secretion (GO:0033605) | 4.16686592 |
29 | synaptic vesicle docking involved in exocytosis (GO:0016081) | 4.14591254 |
30 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.09560643 |
31 | neurotransmitter secretion (GO:0007269) | 4.08120049 |
32 | prepulse inhibition (GO:0060134) | 4.07998676 |
33 | regulation of glutamate secretion (GO:0014048) | 4.03339802 |
34 | regulation of synapse structural plasticity (GO:0051823) | 3.97820409 |
35 | neurotransmitter-gated ion channel clustering (GO:0072578) | 3.92004639 |
36 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 3.91806626 |
37 | synaptic vesicle transport (GO:0048489) | 3.89999825 |
38 | establishment of synaptic vesicle localization (GO:0097480) | 3.89999825 |
39 | potassium ion homeostasis (GO:0055075) | 3.88737634 |
40 | regulation of synaptic vesicle transport (GO:1902803) | 3.87396724 |
41 | regulation of catecholamine uptake involved in synaptic transmission (GO:0051940) | 3.86906378 |
42 | regulation of dopamine uptake involved in synaptic transmission (GO:0051584) | 3.86906378 |
43 | cell communication by electrical coupling involved in cardiac conduction (GO:0086064) | 3.84235793 |
44 | ionotropic glutamate receptor signaling pathway (GO:0035235) | 3.81657004 |
45 | protein localization to synapse (GO:0035418) | 3.79516452 |
46 | membrane repolarization during cardiac muscle cell action potential (GO:0086013) | 3.79148924 |
47 | axonal fasciculation (GO:0007413) | 3.78940855 |
48 | regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310) | 3.76025008 |
49 | synaptic transmission, glutamatergic (GO:0035249) | 3.74199447 |
50 | neuron cell-cell adhesion (GO:0007158) | 3.70134190 |
51 | detection of calcium ion (GO:0005513) | 3.69860193 |
52 | respiratory electron transport chain (GO:0022904) | 3.69562954 |
53 | response to dietary excess (GO:0002021) | 3.69537682 |
54 | positive regulation of amine transport (GO:0051954) | 3.69316876 |
55 | glutamate secretion (GO:0014047) | 3.68833638 |
56 | long-term synaptic potentiation (GO:0060291) | 3.65116913 |
57 | cardiac left ventricle morphogenesis (GO:0003214) | 3.64123837 |
58 | positive regulation of synaptic transmission, glutamatergic (GO:0051968) | 3.62469897 |
59 | cerebellar Purkinje cell layer development (GO:0021680) | 3.58659040 |
60 | electron transport chain (GO:0022900) | 3.58057942 |
61 | neuron-neuron synaptic transmission (GO:0007270) | 3.50873422 |
62 | regulation of neuronal synaptic plasticity (GO:0048168) | 3.49691443 |
63 | negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315) | 3.47475137 |
64 | multicellular organismal reproductive behavior (GO:0033057) | 3.47247557 |
65 | regulation of long-term neuronal synaptic plasticity (GO:0048169) | 3.47045239 |
66 | positive regulation of potassium ion transmembrane transport (GO:1901381) | 3.43058651 |
67 | neuronal ion channel clustering (GO:0045161) | 3.40529875 |
68 | cellular sodium ion homeostasis (GO:0006883) | 3.39232889 |
69 | gamma-aminobutyric acid transport (GO:0015812) | 3.39055552 |
70 | amino acid import (GO:0043090) | 3.37471382 |
71 | transmission of nerve impulse (GO:0019226) | 3.37004037 |
72 | regulation of feeding behavior (GO:0060259) | 3.35601375 |
73 | membrane repolarization during action potential (GO:0086011) | 3.34929871 |
74 | regulation of dopamine secretion (GO:0014059) | 3.34390270 |
75 | cell communication by electrical coupling (GO:0010644) | 3.34284711 |
76 | layer formation in cerebral cortex (GO:0021819) | 3.31765830 |
77 | potassium ion import (GO:0010107) | 3.30900140 |
78 | negative regulation of membrane potential (GO:0045837) | 3.29106190 |
79 | dicarboxylic acid transport (GO:0006835) | 3.28255604 |
80 | exploration behavior (GO:0035640) | 3.27954304 |
81 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.25842928 |
82 | regulation of synaptic transmission, GABAergic (GO:0032228) | 3.25158100 |
83 | regulation of vesicle fusion (GO:0031338) | 3.24064376 |
84 | acid secretion (GO:0046717) | 3.23173709 |
85 | regulation of neurotransmitter uptake (GO:0051580) | 3.22706711 |
86 | startle response (GO:0001964) | 3.21884229 |
87 | regulation of synaptic transmission, glutamatergic (GO:0051966) | 3.21653078 |
88 | behavioral response to cocaine (GO:0048148) | 3.21081275 |
89 | membrane depolarization (GO:0051899) | 3.20963404 |
90 | regulation of sensory perception of pain (GO:0051930) | 3.20808273 |
91 | regulation of sensory perception (GO:0051931) | 3.20808273 |
92 | glutamate receptor signaling pathway (GO:0007215) | 3.20428450 |
93 | neurotransmitter transport (GO:0006836) | 3.20076122 |
94 | acidic amino acid transport (GO:0015800) | 3.19911627 |
95 | L-glutamate transport (GO:0015813) | 3.19495431 |
96 | regulation of excitatory postsynaptic membrane potential (GO:0060079) | 3.17888913 |
97 | cellular response to glucagon stimulus (GO:0071377) | 3.17660099 |
98 | transferrin transport (GO:0033572) | 3.17548905 |
99 | positive regulation of neurotransmitter transport (GO:0051590) | 3.17083946 |
100 | positive regulation of neurotransmitter secretion (GO:0001956) | 3.15410002 |
101 | Golgi transport vesicle coating (GO:0048200) | 3.14670294 |
102 | COPI coating of Golgi vesicle (GO:0048205) | 3.14670294 |
103 | energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988) | 3.14054185 |
104 | ATP hydrolysis coupled proton transport (GO:0015991) | 3.14054185 |
105 | negative regulation of synaptic transmission, GABAergic (GO:0032229) | 3.13100845 |
106 | hydrogen ion transmembrane transport (GO:1902600) | 3.11829433 |
107 | membrane depolarization during action potential (GO:0086010) | 3.11601725 |
108 | regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882) | 3.11199854 |
109 | regulation of amino acid transport (GO:0051955) | 3.11065875 |
110 | positive regulation of membrane potential (GO:0045838) | 3.11022752 |
111 | regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371) | 3.09884128 |
112 | positive regulation of actin filament depolymerization (GO:0030836) | 3.09419416 |
113 | regulation of dopamine metabolic process (GO:0042053) | 3.08778733 |
114 | regulation of catecholamine metabolic process (GO:0042069) | 3.08778733 |
115 | synaptic transmission, dopaminergic (GO:0001963) | 3.07774250 |
116 | regulation of inhibitory postsynaptic membrane potential (GO:0060080) | 3.07680314 |
117 | neuron recognition (GO:0008038) | 3.07385809 |
118 | regulation of synaptic transmission, dopaminergic (GO:0032225) | 3.06865328 |
119 | regulation of synaptic plasticity (GO:0048167) | 3.06862607 |
120 | synapse assembly (GO:0007416) | 3.06839002 |
121 | cochlea development (GO:0090102) | 3.06749003 |
122 | positive regulation of synaptic transmission (GO:0050806) | 3.05837272 |
123 | negative regulation of synaptic transmission, glutamatergic (GO:0051967) | 3.05718409 |
124 | adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191) | 3.05699387 |
125 | multi-organism reproductive behavior (GO:0044705) | 3.05132492 |
126 | long-term memory (GO:0007616) | 3.04870444 |
127 | negative regulation of phosphoprotein phosphatase activity (GO:0032515) | 3.03724701 |
128 | regulation of norepinephrine secretion (GO:0014061) | 3.03333481 |
129 | insulin secretion (GO:0030073) | 3.01930717 |
130 | proline transport (GO:0015824) | 3.00647495 |
131 | regulation of neurotransmitter levels (GO:0001505) | 3.00161507 |
132 | neuromuscular process controlling posture (GO:0050884) | 3.00075745 |
133 | vesicle docking involved in exocytosis (GO:0006904) | 2.99817741 |
134 | membrane repolarization (GO:0086009) | 2.99780597 |
135 | regulation of neurotransmitter transport (GO:0051588) | 2.98588563 |
136 | succinate metabolic process (GO:0006105) | 2.97968954 |
137 | glycine transport (GO:0015816) | 2.97425272 |
138 | * synaptic transmission (GO:0007268) | 2.96607442 |
139 | ferric iron transport (GO:0015682) | 2.96547378 |
140 | trivalent inorganic cation transport (GO:0072512) | 2.96547378 |
141 | neuronal action potential propagation (GO:0019227) | 2.95921040 |
142 | fear response (GO:0042596) | 2.92302997 |
143 | regulation of postsynaptic membrane potential (GO:0060078) | 2.91915181 |
144 | maternal behavior (GO:0042711) | 2.91029300 |
145 | regulation of neurotransmitter secretion (GO:0046928) | 2.90898247 |
146 | behavioral fear response (GO:0001662) | 2.87680167 |
147 | behavioral defense response (GO:0002209) | 2.87680167 |
148 | reproductive behavior (GO:0019098) | 2.84592056 |
149 | dopamine receptor signaling pathway (GO:0007212) | 2.84236266 |
150 | regulation of exocytosis (GO:0017157) | 2.83835011 |
151 | learning (GO:0007612) | 2.83510963 |
152 | positive regulation of synapse maturation (GO:0090129) | 2.81755770 |
153 | social behavior (GO:0035176) | 2.81649166 |
154 | intraspecies interaction between organisms (GO:0051703) | 2.81649166 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EZH2_22144423_ChIP-Seq_EOC_Human | 6.09578102 |
2 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 4.66275507 |
3 | GBX2_23144817_ChIP-Seq_PC3_Human | 4.46560546 |
4 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 3.73750346 |
5 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 3.19938435 |
6 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 2.98734946 |
7 | * REST_21632747_ChIP-Seq_MESCs_Mouse | 2.93612494 |
8 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 2.81887323 |
9 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 2.81037396 |
10 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 2.72545950 |
11 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 2.66966573 |
12 | DROSHA_22980978_ChIP-Seq_HELA_Human | 2.60107213 |
13 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 2.59835877 |
14 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 2.56076946 |
15 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.52544023 |
16 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 2.51775322 |
17 | * REST_18959480_ChIP-ChIP_MESCs_Mouse | 2.50518954 |
18 | EGR1_19032775_ChIP-ChIP_M12_Human | 2.50067740 |
19 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 2.47234099 |
20 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 2.47234099 |
21 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 2.44938330 |
22 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 2.41545132 |
23 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 2.28720728 |
24 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 2.26689929 |
25 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.16228627 |
26 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.09848272 |
27 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 2.09606030 |
28 | * EZH2_27294783_Chip-Seq_ESCs_Mouse | 2.09519885 |
29 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 2.06663081 |
30 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.94493053 |
31 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.93704629 |
32 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.88787158 |
33 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 1.85087688 |
34 | FUS_26573619_Chip-Seq_HEK293_Human | 1.79662789 |
35 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.73491637 |
36 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.69159551 |
37 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.67034369 |
38 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.66690761 |
39 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.65768911 |
40 | * SMAD4_21799915_ChIP-Seq_A2780_Human | 1.62189765 |
41 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.61752931 |
42 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.61241767 |
43 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.60426316 |
44 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.47003276 |
45 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.46232949 |
46 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 1.44062974 |
47 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.43473101 |
48 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.43121868 |
49 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.39082808 |
50 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.37915085 |
51 | P300_19829295_ChIP-Seq_ESCs_Human | 1.37215400 |
52 | * NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.33475904 |
53 | * SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.33007285 |
54 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 1.32677667 |
55 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.32458697 |
56 | STAT3_23295773_ChIP-Seq_U87_Human | 1.29602961 |
57 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.28085826 |
58 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.27341602 |
59 | * SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.26341134 |
60 | * RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 1.25872728 |
61 | * TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.24927039 |
62 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.23688941 |
63 | YAP1_20516196_ChIP-Seq_MESCs_Mouse | 1.22608303 |
64 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.21839700 |
65 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.21275368 |
66 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.20870664 |
67 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.17294642 |
68 | AR_25329375_ChIP-Seq_VCAP_Human | 1.17208596 |
69 | GATA3_20176728_ChIP-ChIP_TSCs_Mouse | 1.16834565 |
70 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.16594708 |
71 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.15798916 |
72 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.15232119 |
73 | TCF4_23295773_ChIP-Seq_U87_Human | 1.14422440 |
74 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.12999566 |
75 | * AR_19668381_ChIP-Seq_PC3_Human | 1.11787461 |
76 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.10930559 |
77 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.09696859 |
78 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.09332941 |
79 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.07885445 |
80 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.07762507 |
81 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.07621179 |
82 | SOX9_26525672_Chip-Seq_HEART_Mouse | 1.07416747 |
83 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.06499308 |
84 | * RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.06441878 |
85 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.06412997 |
86 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.06072180 |
87 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 1.04719372 |
88 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 1.04573799 |
89 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.04530090 |
90 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 1.03563796 |
91 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.02898762 |
92 | * WT1_25993318_ChIP-Seq_PODOCYTE_Human | 1.02633184 |
93 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 1.01657569 |
94 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.01588149 |
95 | * P53_22387025_ChIP-Seq_ESCs_Mouse | 1.00540059 |
96 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 0.99902132 |
97 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.99081856 |
98 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.99081856 |
99 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 0.98548621 |
100 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.98445270 |
101 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 0.96486447 |
102 | * E2F1_18555785_Chip-Seq_ESCs_Mouse | 0.95348527 |
103 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 0.93891239 |
104 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 0.93547963 |
105 | * CMYC_18555785_Chip-Seq_ESCs_Mouse | 0.93071550 |
106 | MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 0.92819698 |
107 | SMAD3_21741376_ChIP-Seq_ESCs_Human | 0.92670912 |
108 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 0.91927201 |
109 | * EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 0.91925456 |
110 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 0.91361036 |
111 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 0.91350431 |
112 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.90748718 |
113 | * BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 0.90231476 |
114 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 0.90190907 |
115 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 0.89752525 |
116 | TP53_22573176_ChIP-Seq_HFKS_Human | 0.89587445 |
117 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.89170265 |
118 | JUN_21703547_ChIP-Seq_K562_Human | 0.89032912 |
119 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.88053832 |
120 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 0.87480840 |
121 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.86140706 |
122 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.86140706 |
123 | LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.85665205 |
124 | * SMAD4_21741376_ChIP-Seq_HESCs_Human | 0.85493560 |
125 | * SMAD4_21741376_ChIP-Seq_EPCs_Human | 0.85378027 |
126 | TAL1_26923725_Chip-Seq_HPCs_Mouse | 0.85157515 |
127 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.85097833 |
128 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 0.84766745 |
129 | REST_19997604_ChIP-ChIP_NEURONS_Mouse | 0.84598329 |
130 | * SUZ12_18555785_Chip-Seq_ESCs_Mouse | 0.84427984 |
131 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.83346388 |
132 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 0.83346388 |
133 | EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 0.81953891 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0004859_abnormal_synaptic_plasticity | 4.50647234 |
2 | MP0002822_catalepsy | 4.13494601 |
3 | MP0004270_analgesia | 3.68164622 |
4 | MP0003635_abnormal_synaptic_transmissio | 3.56291048 |
5 | MP0005646_abnormal_pituitary_gland | 3.52087389 |
6 | MP0009780_abnormal_chondrocyte_physiolo | 3.40904254 |
7 | MP0002909_abnormal_adrenal_gland | 3.19418747 |
8 | MP0005645_abnormal_hypothalamus_physiol | 3.09728791 |
9 | MP0000013_abnormal_adipose_tissue | 2.99770846 |
10 | * MP0002063_abnormal_learning/memory/cond | 2.96757468 |
11 | MP0003880_abnormal_central_pattern | 2.91910940 |
12 | * MP0009745_abnormal_behavioral_response | 2.88035928 |
13 | * MP0002064_seizures | 2.77337993 |
14 | MP0009046_muscle_twitch | 2.70261617 |
15 | MP0003122_maternal_imprinting | 2.67067487 |
16 | * MP0002572_abnormal_emotion/affect_behav | 2.47749320 |
17 | MP0002272_abnormal_nervous_system | 2.44770983 |
18 | MP0003283_abnormal_digestive_organ | 2.42396554 |
19 | MP0001968_abnormal_touch/_nociception | 2.24426377 |
20 | * MP0002734_abnormal_mechanical_nocicepti | 2.23064724 |
21 | MP0001529_abnormal_vocalization | 2.16406888 |
22 | MP0001486_abnormal_startle_reflex | 2.07088347 |
23 | MP0002837_dystrophic_cardiac_calcinosis | 2.04773409 |
24 | MP0002876_abnormal_thyroid_physiology | 2.01372062 |
25 | MP0001501_abnormal_sleep_pattern | 2.00025316 |
26 | MP0003879_abnormal_hair_cell | 1.98969359 |
27 | MP0003787_abnormal_imprinting | 1.85124703 |
28 | MP0004043_abnormal_pH_regulation | 1.83659536 |
29 | MP0010386_abnormal_urinary_bladder | 1.81577947 |
30 | MP0005379_endocrine/exocrine_gland_phen | 1.79805920 |
31 | MP0002733_abnormal_thermal_nociception | 1.71368521 |
32 | MP0002736_abnormal_nociception_after | 1.70713607 |
33 | MP0003195_calcinosis | 1.67557546 |
34 | * MP0001970_abnormal_pain_threshold | 1.63817780 |
35 | MP0005386_behavior/neurological_phenoty | 1.63146947 |
36 | MP0004924_abnormal_behavior | 1.63146947 |
37 | MP0005423_abnormal_somatic_nervous | 1.62501314 |
38 | MP0001984_abnormal_olfaction | 1.51563819 |
39 | MP0004147_increased_porphyrin_level | 1.49253101 |
40 | MP0002557_abnormal_social/conspecific_i | 1.45287086 |
41 | MP0006276_abnormal_autonomic_nervous | 1.43915113 |
42 | MP0002735_abnormal_chemical_nociception | 1.43269271 |
43 | MP0001440_abnormal_grooming_behavior | 1.42553775 |
44 | MP0002693_abnormal_pancreas_physiology | 1.42006852 |
45 | * MP0002067_abnormal_sensory_capabilities | 1.40493741 |
46 | MP0001963_abnormal_hearing_physiology | 1.32108071 |
47 | MP0004142_abnormal_muscle_tone | 1.27186456 |
48 | MP0002877_abnormal_melanocyte_morpholog | 1.26338779 |
49 | MP0008569_lethality_at_weaning | 1.25706779 |
50 | MP0000003_abnormal_adipose_tissue | 1.24901826 |
51 | MP0008875_abnormal_xenobiotic_pharmacok | 1.24444443 |
52 | MP0001986_abnormal_taste_sensitivity | 1.24360331 |
53 | MP0001944_abnormal_pancreas_morphology | 1.22785612 |
54 | MP0003329_amyloid_beta_deposits | 1.22600388 |
55 | MP0000955_abnormal_spinal_cord | 1.20087389 |
56 | MP0002163_abnormal_gland_morphology | 1.19570767 |
57 | * MP0002066_abnormal_motor_capabilities/c | 1.19425417 |
58 | MP0004811_abnormal_neuron_physiology | 1.18994946 |
59 | MP0001502_abnormal_circadian_rhythm | 1.15882101 |
60 | MP0004215_abnormal_myocardial_fiber | 1.13683149 |
61 | MP0001905_abnormal_dopamine_level | 1.13430807 |
62 | MP0002184_abnormal_innervation | 1.11758555 |
63 | MP0002638_abnormal_pupillary_reflex | 1.08271674 |
64 | MP0000631_abnormal_neuroendocrine_gland | 1.05325644 |
65 | MP0003183_abnormal_peptide_metabolism | 1.05063567 |
66 | * MP0005535_abnormal_body_temperature | 1.04252553 |
67 | MP0008961_abnormal_basal_metabolism | 1.03089869 |
68 | MP0001346_abnormal_lacrimal_gland | 1.01764996 |
69 | * MP0002069_abnormal_eating/drinking_beha | 1.01584437 |
70 | MP0005623_abnormal_meninges_morphology | 1.01019121 |
71 | MP0004858_abnormal_nervous_system | 1.00887533 |
72 | * MP0002078_abnormal_glucose_homeostasis | 1.00093547 |
73 | MP0002882_abnormal_neuron_morphology | 0.97893289 |
74 | MP0003690_abnormal_glial_cell | 0.97057308 |
75 | MP0000751_myopathy | 0.95513487 |
76 | MP0004085_abnormal_heartbeat | 0.95266475 |
77 | MP0001485_abnormal_pinna_reflex | 0.95228890 |
78 | MP0005410_abnormal_fertilization | 0.95131121 |
79 | MP0000778_abnormal_nervous_system | 0.94844484 |
80 | MP0010234_abnormal_vibrissa_follicle | 0.94612336 |
81 | MP0003633_abnormal_nervous_system | 0.91327041 |
82 | MP0003634_abnormal_glial_cell | 0.88713854 |
83 | MP0008872_abnormal_physiological_respon | 0.86975496 |
84 | MP0001765_abnormal_ion_homeostasis | 0.81870563 |
85 | * MP0003953_abnormal_hormone_level | 0.81852246 |
86 | MP0000639_abnormal_adrenal_gland | 0.81748122 |
87 | MP0002229_neurodegeneration | 0.81043204 |
88 | MP0001177_atelectasis | 0.79302023 |
89 | MP0004885_abnormal_endolymph | 0.78633983 |
90 | MP0002653_abnormal_ependyma_morphology | 0.78122051 |
91 | MP0002752_abnormal_somatic_nervous | 0.77344544 |
92 | MP0001664_abnormal_digestion | 0.77114193 |
93 | MP0003121_genomic_imprinting | 0.76535082 |
94 | MP0003123_paternal_imprinting | 0.76146096 |
95 | MP0005187_abnormal_penis_morphology | 0.75599945 |
96 | MP0003045_fibrosis | 0.73941081 |
97 | MP0003172_abnormal_lysosome_physiology | 0.72556889 |
98 | MP0008874_decreased_physiological_sensi | 0.72537793 |
99 | * MP0002152_abnormal_brain_morphology | 0.70526652 |
100 | * MP0006036_abnormal_mitochondrial_physio | 0.70341112 |
101 | MP0004130_abnormal_muscle_cell | 0.69839253 |
102 | MP0003631_nervous_system_phenotype | 0.69677227 |
103 | MP0003075_altered_response_to | 0.68621144 |
104 | MP0000026_abnormal_inner_ear | 0.67123039 |
105 | MP0002090_abnormal_vision | 0.67113100 |
106 | MP0008995_early_reproductive_senescence | 0.65392425 |
107 | MP0008877_abnormal_DNA_methylation | 0.64840580 |
108 | MP0005499_abnormal_olfactory_system | 0.63860159 |
109 | MP0005394_taste/olfaction_phenotype | 0.63860159 |
110 | MP0005058_abnormal_lysosome_morphology | 0.63856945 |
111 | MP0005551_abnormal_eye_electrophysiolog | 0.63462102 |
112 | MP0000681_abnormal_thyroid_gland | 0.61246667 |
113 | MP0003137_abnormal_impulse_conducting | 0.58220009 |
114 | MP0006072_abnormal_retinal_apoptosis | 0.57854964 |
115 | MP0003878_abnormal_ear_physiology | 0.57739803 |
116 | MP0005377_hearing/vestibular/ear_phenot | 0.57739803 |
117 | MP0003632_abnormal_nervous_system | 0.57656401 |
118 | MP0003698_abnormal_male_reproductive | 0.56563888 |
119 | MP0005448_abnormal_energy_balance | 0.56408337 |
120 | MP0000230_abnormal_systemic_arterial | 0.55513222 |
121 | MP0001188_hyperpigmentation | 0.54978468 |
122 | MP0005167_abnormal_blood-brain_barrier | 0.52478720 |
123 | MP0001943_abnormal_respiration | 0.51762453 |
124 | MP0006138_congestive_heart_failure | 0.50920175 |
125 | MP0001348_abnormal_lacrimal_gland | 0.48742540 |
126 | MP0000604_amyloidosis | 0.48213817 |
127 | * MP0003956_abnormal_body_size | 0.48062858 |
128 | MP0005253_abnormal_eye_physiology | 0.47449649 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Myokymia (HP:0002411) | 5.56147439 |
2 | Focal motor seizures (HP:0011153) | 5.40261692 |
3 | Neuroendocrine neoplasm (HP:0100634) | 4.68177483 |
4 | Pheochromocytoma (HP:0002666) | 4.55664482 |
5 | Visual hallucinations (HP:0002367) | 4.42936722 |
6 | Elevated circulating parathyroid hormone (PTH) level (HP:0003165) | 4.06004057 |
7 | Resting tremor (HP:0002322) | 3.94042281 |
8 | Acute necrotizing encephalopathy (HP:0006965) | 3.89033029 |
9 | Focal seizures (HP:0007359) | 3.72041474 |
10 | Progressive macrocephaly (HP:0004481) | 3.60354431 |
11 | Anxiety (HP:0000739) | 3.52221646 |
12 | Agitation (HP:0000713) | 3.42697346 |
13 | Generalized tonic-clonic seizures (HP:0002069) | 3.40033910 |
14 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.34985029 |
15 | Absence seizures (HP:0002121) | 3.18866763 |
16 | Mitochondrial inheritance (HP:0001427) | 3.14931152 |
17 | Epileptic encephalopathy (HP:0200134) | 3.13864096 |
18 | Delusions (HP:0000746) | 3.12867195 |
19 | Sensory axonal neuropathy (HP:0003390) | 3.12160882 |
20 | Depression (HP:0000716) | 3.09442863 |
21 | Atonic seizures (HP:0010819) | 3.08423703 |
22 | Hyperinsulinemic hypoglycemia (HP:0000825) | 3.06174439 |
23 | Dysdiadochokinesis (HP:0002075) | 3.02979186 |
24 | Acute encephalopathy (HP:0006846) | 3.00228556 |
25 | Progressive cerebellar ataxia (HP:0002073) | 2.99113738 |
26 | Dialeptic seizures (HP:0011146) | 2.94340213 |
27 | Hyperventilation (HP:0002883) | 2.87898576 |
28 | Epileptiform EEG discharges (HP:0011182) | 2.87723298 |
29 | EEG with generalized epileptiform discharges (HP:0011198) | 2.83791505 |
30 | Abnormal eating behavior (HP:0100738) | 2.82169230 |
31 | Papilledema (HP:0001085) | 2.82091544 |
32 | Hepatocellular necrosis (HP:0001404) | 2.81117437 |
33 | Sleep apnea (HP:0010535) | 2.78635630 |
34 | Hypsarrhythmia (HP:0002521) | 2.78091692 |
35 | Neoplasm of the peripheral nervous system (HP:0100007) | 2.77630686 |
36 | Failure to thrive in infancy (HP:0001531) | 2.76703986 |
37 | Increased CSF lactate (HP:0002490) | 2.75953615 |
38 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 2.75757411 |
39 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 2.75757411 |
40 | Hypercortisolism (HP:0001578) | 2.75104024 |
41 | Impaired social interactions (HP:0000735) | 2.74637371 |
42 | Abnormal social behavior (HP:0012433) | 2.74637371 |
43 | Intention tremor (HP:0002080) | 2.74208552 |
44 | Mutism (HP:0002300) | 2.73657253 |
45 | Truncal ataxia (HP:0002078) | 2.65630748 |
46 | Hypoglycemic seizures (HP:0002173) | 2.65094194 |
47 | Fetal akinesia sequence (HP:0001989) | 2.64619926 |
48 | Inability to walk (HP:0002540) | 2.59848335 |
49 | Abnormality of calcium-phosphate metabolism (HP:0100530) | 2.59064426 |
50 | Hyperthyroidism (HP:0000836) | 2.55793692 |
51 | Optic nerve hypoplasia (HP:0000609) | 2.55267352 |
52 | Myotonia (HP:0002486) | 2.53558277 |
53 | Retinal atrophy (HP:0001105) | 2.47907375 |
54 | Ankyloglossia (HP:0010296) | 2.47239143 |
55 | Retinal dysplasia (HP:0007973) | 2.47088092 |
56 | Akinesia (HP:0002304) | 2.42103312 |
57 | Status epilepticus (HP:0002133) | 2.42077306 |
58 | Amblyopia (HP:0000646) | 2.42023504 |
59 | Vaginal atresia (HP:0000148) | 2.41056352 |
60 | Gait imbalance (HP:0002141) | 2.40509623 |
61 | Symptomatic seizures (HP:0011145) | 2.39600883 |
62 | Genital tract atresia (HP:0001827) | 2.39426842 |
63 | Split foot (HP:0001839) | 2.39019933 |
64 | Diplopia (HP:0000651) | 2.38414544 |
65 | Abnormality of binocular vision (HP:0011514) | 2.38414544 |
66 | Cholecystitis (HP:0001082) | 2.36973373 |
67 | Abnormal gallbladder physiology (HP:0012438) | 2.36973373 |
68 | Cerebral hypomyelination (HP:0006808) | 2.36715585 |
69 | * Dysmetria (HP:0001310) | 2.36027593 |
70 | Macroorchidism (HP:0000053) | 2.35832877 |
71 | Cerebral inclusion bodies (HP:0100314) | 2.35773522 |
72 | Insulin-resistant diabetes mellitus (HP:0000831) | 2.34045138 |
73 | Polyphagia (HP:0002591) | 2.33746162 |
74 | Cerebral edema (HP:0002181) | 2.32508165 |
75 | Abnormality of the corticospinal tract (HP:0002492) | 2.32268299 |
76 | Abnormality of the labia minora (HP:0012880) | 2.30827972 |
77 | Postural tremor (HP:0002174) | 2.29167319 |
78 | Poor eye contact (HP:0000817) | 2.28847747 |
79 | Focal dystonia (HP:0004373) | 2.27820784 |
80 | * Impaired vibration sensation in the lower limbs (HP:0002166) | 2.27535505 |
81 | Increased hepatocellular lipid droplets (HP:0006565) | 2.27433641 |
82 | Broad-based gait (HP:0002136) | 2.26486092 |
83 | Action tremor (HP:0002345) | 2.24286654 |
84 | Abnormal pancreas size (HP:0012094) | 2.23842533 |
85 | Scanning speech (HP:0002168) | 2.23513057 |
86 | Absent speech (HP:0001344) | 2.23238905 |
87 | Congenital primary aphakia (HP:0007707) | 2.22102863 |
88 | Ketoacidosis (HP:0001993) | 2.22040037 |
89 | Leukodystrophy (HP:0002415) | 2.21431367 |
90 | Dysostosis multiplex (HP:0000943) | 2.20971078 |
91 | Hepatic necrosis (HP:0002605) | 2.19260533 |
92 | Torticollis (HP:0000473) | 2.17101218 |
93 | Febrile seizures (HP:0002373) | 2.16500789 |
94 | Gaze-evoked nystagmus (HP:0000640) | 2.16368669 |
95 | Potter facies (HP:0002009) | 2.15648027 |
96 | Facial shape deformation (HP:0011334) | 2.15648027 |
97 | Nephrogenic diabetes insipidus (HP:0009806) | 2.12633711 |
98 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 2.12472023 |
99 | Medial flaring of the eyebrow (HP:0010747) | 2.11311162 |
100 | Dysmetric saccades (HP:0000641) | 2.10417791 |
101 | Oligomenorrhea (HP:0000876) | 2.08456265 |
102 | Type II lissencephaly (HP:0007260) | 2.08095601 |
103 | Urinary urgency (HP:0000012) | 2.07620053 |
104 | Supranuclear gaze palsy (HP:0000605) | 2.07501506 |
105 | Craniofacial dystonia (HP:0012179) | 2.07380351 |
106 | Prolonged QT interval (HP:0001657) | 2.05912036 |
107 | Drooling (HP:0002307) | 2.05056150 |
108 | Excessive salivation (HP:0003781) | 2.05056150 |
109 | Rapidly progressive (HP:0003678) | 2.04913252 |
110 | Abnormality of endocrine pancreas physiology (HP:0012093) | 2.04576261 |
111 | Abnormality of the pancreatic islet cells (HP:0006476) | 2.04576261 |
112 | Optic disc pallor (HP:0000543) | 2.03762746 |
113 | Ankle clonus (HP:0011448) | 2.03686448 |
114 | Menstrual irregularities (HP:0000858) | 2.03578218 |
115 | Lower limb muscle weakness (HP:0007340) | 2.03518136 |
116 | Esotropia (HP:0000565) | 2.03173301 |
117 | X-linked dominant inheritance (HP:0001423) | 2.00775345 |
118 | Spinal canal stenosis (HP:0003416) | 2.00273345 |
119 | Poor suck (HP:0002033) | 2.00042713 |
120 | * Neuronal loss in central nervous system (HP:0002529) | 1.99857818 |
121 | Psychosis (HP:0000709) | 1.99443960 |
122 | Spastic gait (HP:0002064) | 1.99412925 |
123 | Abnormal EKG (HP:0003115) | 1.92255000 |
124 | Impaired pain sensation (HP:0007328) | 1.91794000 |
125 | Abnormality of pain sensation (HP:0010832) | 1.91794000 |
126 | Increased intramyocellular lipid droplets (HP:0012240) | 1.91103568 |
127 | Hypoventilation (HP:0002791) | 1.90788534 |
128 | Renal Fanconi syndrome (HP:0001994) | 1.89900743 |
129 | Bradykinesia (HP:0002067) | 1.89710225 |
130 | Limb dystonia (HP:0002451) | 1.88735548 |
131 | Emotional lability (HP:0000712) | 1.88255661 |
132 | Pancreatic islet-cell hyperplasia (HP:0004510) | 1.87584587 |
133 | Urinary bladder sphincter dysfunction (HP:0002839) | 1.87484428 |
134 | * Impaired vibratory sensation (HP:0002495) | 1.86946649 |
135 | Spastic tetraplegia (HP:0002510) | 1.86145190 |
136 | Gout (HP:0001997) | 1.85622003 |
137 | Respiratory failure (HP:0002878) | 1.84854135 |
138 | Hemiparesis (HP:0001269) | 1.84625052 |
139 | Restlessness (HP:0000711) | 1.84159201 |
140 | Abnormal hair whorl (HP:0010721) | 1.83480021 |
141 | Abnormality of oral frenula (HP:0000190) | 1.83199319 |
142 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 1.83010806 |
143 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 1.83010806 |
144 | Blue irides (HP:0000635) | 1.82789983 |
145 | Specific learning disability (HP:0001328) | 1.82660508 |
146 | Hyperglycemia (HP:0003074) | 1.81879745 |
147 | Abnormality of liposaccharide metabolism (HP:0010968) | 1.81653017 |
148 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 1.81653017 |
149 | Abnormality of glycolipid metabolism (HP:0010969) | 1.81653017 |
150 | Lipid accumulation in hepatocytes (HP:0006561) | 1.81595072 |
151 | Postural instability (HP:0002172) | 1.81534970 |
152 | Conjugated hyperbilirubinemia (HP:0002908) | 1.80846830 |
153 | Large for gestational age (HP:0001520) | 1.80263924 |
154 | Impaired smooth pursuit (HP:0007772) | 1.79873667 |
155 | Incomplete penetrance (HP:0003829) | 1.79094825 |
Rank | Gene Set | Z-score |
---|---|---|
1 | NTRK3 | 4.82781412 |
2 | EPHA4 | 4.35335927 |
3 | MAP3K4 | 3.14217205 |
4 | TESK1 | 3.08847108 |
5 | MAP3K9 | 2.83050976 |
6 | MAP2K7 | 2.55701734 |
7 | MAP3K11 | 2.36493143 |
8 | MAP3K2 | 2.27370533 |
9 | LIMK1 | 2.18064472 |
10 | KSR2 | 2.15665095 |
11 | PRKD3 | 2.14889706 |
12 | ARAF | 2.07906910 |
13 | UHMK1 | 1.97801987 |
14 | MINK1 | 1.91959737 |
15 | MAP3K12 | 1.87056615 |
16 | CASK | 1.82812285 |
17 | MAP3K13 | 1.82355564 |
18 | NTRK2 | 1.81474402 |
19 | MAP2K4 | 1.79876158 |
20 | CAMK1G | 1.70101260 |
21 | NME1 | 1.62839841 |
22 | CDK5 | 1.60515717 |
23 | TNIK | 1.60485758 |
24 | NTRK1 | 1.59741629 |
25 | GRK5 | 1.59275236 |
26 | PASK | 1.58525336 |
27 | AKT3 | 1.56902329 |
28 | ALK | 1.56555792 |
29 | PRKCH | 1.50019065 |
30 | MAP3K1 | 1.45980561 |
31 | CAMK1D | 1.45245257 |
32 | MARK1 | 1.44469536 |
33 | DAPK2 | 1.38861311 |
34 | SCYL2 | 1.38155016 |
35 | FES | 1.36838059 |
36 | CAMKK1 | 1.34407610 |
37 | TSSK6 | 1.32211104 |
38 | KSR1 | 1.31255625 |
39 | PRKCG | 1.29719310 |
40 | DAPK1 | 1.29253486 |
41 | CAMKK2 | 1.24371401 |
42 | HIPK2 | 1.22155507 |
43 | PINK1 | 1.21797724 |
44 | PLK2 | 1.20528479 |
45 | TAOK3 | 1.18574049 |
46 | CSNK1G3 | 1.12184257 |
47 | CAMK2B | 1.12058941 |
48 | CSNK1A1L | 1.08059578 |
49 | PAK6 | 1.07923027 |
50 | SIK3 | 1.07615690 |
51 | SIK2 | 1.07035483 |
52 | SGK494 | 1.04963653 |
53 | SGK223 | 1.04963653 |
54 | LATS2 | 1.00922894 |
55 | MOS | 0.97608806 |
56 | INSRR | 0.97300553 |
57 | CAMK2A | 0.96846168 |
58 | CAMK1 | 0.96675751 |
59 | PIK3CG | 0.96163213 |
60 | BRAF | 0.95547982 |
61 | CSNK1G1 | 0.94665350 |
62 | SGK2 | 0.94227759 |
63 | RIPK4 | 0.92488847 |
64 | NEK1 | 0.92236916 |
65 | CAMK2D | 0.92009856 |
66 | CDK19 | 0.88457635 |
67 | CDC42BPA | 0.88231935 |
68 | TAOK1 | 0.85419597 |
69 | BMPR2 | 0.82496540 |
70 | WNK3 | 0.81801913 |
71 | DYRK1A | 0.81543722 |
72 | TESK2 | 0.80974215 |
73 | PRKCE | 0.80089124 |
74 | BCR | 0.78316664 |
75 | SGK1 | 0.78200508 |
76 | FGR | 0.77601921 |
77 | TRIM28 | 0.73731515 |
78 | CAMK2G | 0.73203642 |
79 | MARK2 | 0.70899214 |
80 | MAPK13 | 0.69409088 |
81 | GRK6 | 0.69269460 |
82 | OXSR1 | 0.67651409 |
83 | PLK3 | 0.66565397 |
84 | FRK | 0.65888841 |
85 | TNK2 | 0.63620426 |
86 | RET | 0.62994627 |
87 | PRPF4B | 0.62762157 |
88 | PRKCZ | 0.62521401 |
89 | STK11 | 0.61949862 |
90 | CDK14 | 0.61689664 |
91 | SGK3 | 0.61121990 |
92 | PDPK1 | 0.58975326 |
93 | PDK1 | 0.58728960 |
94 | CDK18 | 0.58487760 |
95 | PTK2B | 0.58365931 |
96 | RPS6KA2 | 0.58303905 |
97 | PAK3 | 0.57651317 |
98 | TYRO3 | 0.57214448 |
99 | RPS6KA3 | 0.55233453 |
100 | NEK6 | 0.54618196 |
101 | MAP2K1 | 0.54475355 |
102 | PNCK | 0.53875682 |
103 | PDK3 | 0.53487508 |
104 | PDK4 | 0.53487508 |
105 | FER | 0.53430892 |
106 | CDK15 | 0.53254338 |
107 | CSNK1G2 | 0.51216304 |
108 | ADRBK2 | 0.50877716 |
109 | PRKACA | 0.50555234 |
110 | STK38 | 0.47994371 |
111 | PHKG2 | 0.47864136 |
112 | PHKG1 | 0.47864136 |
113 | DDR2 | 0.46015196 |
114 | PRKCA | 0.45927595 |
115 | RPS6KB1 | 0.45735152 |
116 | RAF1 | 0.45541902 |
117 | PRKCB | 0.43580903 |
118 | BRSK1 | 0.42366600 |
119 | MAP3K5 | 0.42085284 |
120 | PRKG1 | 0.41782747 |
121 | PDK2 | 0.41311386 |
122 | PRKACG | 0.41189641 |
123 | CSNK1A1 | 0.39900013 |
124 | ADRBK1 | 0.39624555 |
125 | CDK11A | 0.39432047 |
126 | PAK1 | 0.39175790 |
127 | BMPR1B | 0.37222958 |
128 | BUB1 | 0.36718690 |
129 | CDK3 | 0.35046191 |
130 | CSNK1E | 0.30286306 |
131 | ABL2 | 0.29915833 |
132 | FYN | 0.28201831 |
133 | PKN1 | 0.27921132 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 3.58074678 |
2 | Nicotine addiction_Homo sapiens_hsa05033 | 2.90266658 |
3 | GABAergic synapse_Homo sapiens_hsa04727 | 2.87696624 |
4 | Insulin secretion_Homo sapiens_hsa04911 | 2.67306844 |
5 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 2.62242668 |
6 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 2.53513898 |
7 | Morphine addiction_Homo sapiens_hsa05032 | 2.50704107 |
8 | Olfactory transduction_Homo sapiens_hsa04740 | 2.48232474 |
9 | * Amphetamine addiction_Homo sapiens_hsa05031 | 2.43212495 |
10 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 2.40586752 |
11 | Circadian entrainment_Homo sapiens_hsa04713 | 2.33451224 |
12 | Long-term potentiation_Homo sapiens_hsa04720 | 2.26560348 |
13 | * Cocaine addiction_Homo sapiens_hsa05030 | 2.25537354 |
14 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 2.23538717 |
15 | Glutamatergic synapse_Homo sapiens_hsa04724 | 2.14778895 |
16 | Dopaminergic synapse_Homo sapiens_hsa04728 | 2.08187212 |
17 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.06450390 |
18 | Taste transduction_Homo sapiens_hsa04742 | 1.93194213 |
19 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 1.86033866 |
20 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.80795665 |
21 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 1.75440907 |
22 | Salivary secretion_Homo sapiens_hsa04970 | 1.66158907 |
23 | Gastric acid secretion_Homo sapiens_hsa04971 | 1.59555794 |
24 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 1.59497812 |
25 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.59078515 |
26 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.48926804 |
27 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.47011508 |
28 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.46091677 |
29 | Long-term depression_Homo sapiens_hsa04730 | 1.45528072 |
30 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.43557241 |
31 | Renin secretion_Homo sapiens_hsa04924 | 1.42132428 |
32 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.37864288 |
33 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.24445418 |
34 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 1.19263767 |
35 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 1.13953167 |
36 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 1.12450801 |
37 | Gap junction_Homo sapiens_hsa04540 | 1.10400280 |
38 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 1.07683221 |
39 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 1.07314479 |
40 | GnRH signaling pathway_Homo sapiens_hsa04912 | 1.06510830 |
41 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.05408647 |
42 | cAMP signaling pathway_Homo sapiens_hsa04024 | 1.04020442 |
43 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.03702855 |
44 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 1.01637098 |
45 | Protein export_Homo sapiens_hsa03060 | 1.00866340 |
46 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 1.00437176 |
47 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.92334012 |
48 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.90918865 |
49 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.90482771 |
50 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.87948142 |
51 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.87485820 |
52 | Sulfur relay system_Homo sapiens_hsa04122 | 0.83662408 |
53 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.81542485 |
54 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.81215815 |
55 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.80702943 |
56 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.80551508 |
57 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.80287320 |
58 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.77691610 |
59 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.75452885 |
60 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.72300616 |
61 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.72142828 |
62 | Melanogenesis_Homo sapiens_hsa04916 | 0.71973902 |
63 | Alzheimers disease_Homo sapiens_hsa05010 | 0.69958092 |
64 | Phototransduction_Homo sapiens_hsa04744 | 0.69396233 |
65 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.69321159 |
66 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.66569680 |
67 | Parkinsons disease_Homo sapiens_hsa05012 | 0.63507099 |
68 | Glioma_Homo sapiens_hsa05214 | 0.60981323 |
69 | Mineral absorption_Homo sapiens_hsa04978 | 0.60867106 |
70 | Bile secretion_Homo sapiens_hsa04976 | 0.59835423 |
71 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.57692355 |
72 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.57359749 |
73 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.55950586 |
74 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.55753404 |
75 | * Alcoholism_Homo sapiens_hsa05034 | 0.55539547 |
76 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.55465948 |
77 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.55418979 |
78 | Lysosome_Homo sapiens_hsa04142 | 0.54767415 |
79 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.54181986 |
80 | Prion diseases_Homo sapiens_hsa05020 | 0.52988410 |
81 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.49822172 |
82 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.48270179 |
83 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.47271399 |
84 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.47175174 |
85 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.45689241 |
86 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.45084577 |
87 | Phagosome_Homo sapiens_hsa04145 | 0.44579719 |
88 | Proteasome_Homo sapiens_hsa03050 | 0.43311637 |
89 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.43179427 |
90 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.39071295 |
91 | Circadian rhythm_Homo sapiens_hsa04710 | 0.38768409 |
92 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.38368648 |
93 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.38050713 |
94 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.37799906 |
95 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.37102304 |
96 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.36892885 |
97 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.35206334 |
98 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.35053397 |
99 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.32545052 |
100 | RNA polymerase_Homo sapiens_hsa03020 | 0.32100751 |
101 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.32086180 |
102 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.30967272 |
103 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.30240902 |
104 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.29461873 |
105 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.28302447 |
106 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.28112887 |
107 | Axon guidance_Homo sapiens_hsa04360 | 0.27771216 |
108 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.26838347 |
109 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.26677724 |
110 | Purine metabolism_Homo sapiens_hsa00230 | 0.26651440 |
111 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.25961545 |
112 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.25138780 |
113 | Huntingtons disease_Homo sapiens_hsa05016 | 0.24930259 |
114 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.22537354 |
115 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.16366282 |
116 | Carbon metabolism_Homo sapiens_hsa01200 | 0.15139824 |
117 | Metabolic pathways_Homo sapiens_hsa01100 | 0.13019523 |
118 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.12395489 |
119 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.11999733 |
120 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.11564322 |
121 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.09123530 |
122 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.08363441 |
123 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.07418330 |
124 | Endocytosis_Homo sapiens_hsa04144 | 0.06086701 |