PECR

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)7.64090010
2L-phenylalanine catabolic process (GO:0006559)7.64090010
3erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)7.39493379
4L-phenylalanine metabolic process (GO:0006558)7.39493379
5aromatic amino acid family catabolic process (GO:0009074)6.90367502
6glyoxylate metabolic process (GO:0046487)6.31119784
7tryptophan catabolic process (GO:0006569)6.25125629
8indole-containing compound catabolic process (GO:0042436)6.25125629
9indolalkylamine catabolic process (GO:0046218)6.25125629
10cysteine metabolic process (GO:0006534)6.06350385
11tryptophan metabolic process (GO:0006568)5.92473094
12kynurenine metabolic process (GO:0070189)5.89311248
13bile acid biosynthetic process (GO:0006699)5.78852181
14lysine metabolic process (GO:0006553)5.57080456
15lysine catabolic process (GO:0006554)5.57080456
16triglyceride-rich lipoprotein particle remodeling (GO:0034370)5.55244901
17serine family amino acid catabolic process (GO:0009071)5.46349128
18sulfur amino acid catabolic process (GO:0000098)5.45289799
19urea metabolic process (GO:0019627)5.37176155
20urea cycle (GO:0000050)5.37176155
21epoxygenase P450 pathway (GO:0019373)5.16902794
22fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)5.11821758
23alpha-linolenic acid metabolic process (GO:0036109)5.10953852
24aromatic amino acid family metabolic process (GO:0009072)5.06295784
25nitrogen cycle metabolic process (GO:0071941)4.99888945
26negative regulation of fibrinolysis (GO:0051918)4.97183532
27homocysteine metabolic process (GO:0050667)4.96831486
28high-density lipoprotein particle remodeling (GO:0034375)4.88952921
29bile acid metabolic process (GO:0008206)4.88794014
30amino-acid betaine metabolic process (GO:0006577)4.86354274
31peptidyl-glutamic acid carboxylation (GO:0017187)4.83935318
32protein carboxylation (GO:0018214)4.83935318
33alpha-amino acid catabolic process (GO:1901606)4.79267425
34urate metabolic process (GO:0046415)4.78228313
35regulation of fibrinolysis (GO:0051917)4.76529607
36serine family amino acid metabolic process (GO:0009069)4.74293526
37drug catabolic process (GO:0042737)4.71366844
38complement activation, alternative pathway (GO:0006957)4.69517488
39cellular ketone body metabolic process (GO:0046950)4.69159662
40regulation of protein activation cascade (GO:2000257)4.67458385
41blood coagulation, intrinsic pathway (GO:0007597)4.63747155
42glycine metabolic process (GO:0006544)4.63605374
43tyrosine metabolic process (GO:0006570)4.62655679
44drug transmembrane transport (GO:0006855)4.57817388
45serine family amino acid biosynthetic process (GO:0009070)4.56476292
46cellular amino acid catabolic process (GO:0009063)4.49604149
47indolalkylamine metabolic process (GO:0006586)4.46653371
48cellular modified amino acid catabolic process (GO:0042219)4.37938653
49regulation of complement activation (GO:0030449)4.36372869
50coenzyme catabolic process (GO:0009109)4.35508242
51omega-hydroxylase P450 pathway (GO:0097267)4.35430185
52cellular biogenic amine catabolic process (GO:0042402)4.34321510
53amine catabolic process (GO:0009310)4.34321510
54oxidative demethylation (GO:0070989)4.29925345
55regulation of triglyceride catabolic process (GO:0010896)4.29593777
56regulation of cholesterol esterification (GO:0010872)4.28325393
57benzene-containing compound metabolic process (GO:0042537)4.25227319
58glutamate metabolic process (GO:0006536)4.23781886
59triglyceride homeostasis (GO:0070328)4.20318482
60acylglycerol homeostasis (GO:0055090)4.20318482
61negative regulation of cholesterol transport (GO:0032375)4.20263282
62negative regulation of sterol transport (GO:0032372)4.20263282
63cellular glucuronidation (GO:0052695)4.20153914
64aldehyde catabolic process (GO:0046185)4.19374854
65short-chain fatty acid metabolic process (GO:0046459)4.18594578
66reverse cholesterol transport (GO:0043691)4.16559344
67exogenous drug catabolic process (GO:0042738)4.14759584
68plasma lipoprotein particle remodeling (GO:0034369)4.14608873
69protein-lipid complex remodeling (GO:0034368)4.14608873
70macromolecular complex remodeling (GO:0034367)4.14608873
71ethanol oxidation (GO:0006069)4.13909172
72intestinal cholesterol absorption (GO:0030299)4.10300863
73aspartate family amino acid catabolic process (GO:0009068)4.08064704
74bile acid and bile salt transport (GO:0015721)4.06458163
75ketone body metabolic process (GO:1902224)4.05204384
76imidazole-containing compound metabolic process (GO:0052803)4.03176326
77very-low-density lipoprotein particle assembly (GO:0034379)4.01593095
78phenylpropanoid metabolic process (GO:0009698)3.99554260
79ethanol metabolic process (GO:0006067)3.99312707
80organic acid catabolic process (GO:0016054)3.95595563
81carboxylic acid catabolic process (GO:0046395)3.95595563
82acetyl-CoA metabolic process (GO:0006084)3.90939855
83phospholipid efflux (GO:0033700)3.88718068
84arginine metabolic process (GO:0006525)3.87592911
85drug transport (GO:0015893)3.85520836
86glucuronate metabolic process (GO:0019585)3.81532240
87uronic acid metabolic process (GO:0006063)3.81532240
88plasma lipoprotein particle clearance (GO:0034381)3.80694646
89dicarboxylic acid biosynthetic process (GO:0043650)3.73654256
902-oxoglutarate metabolic process (GO:0006103)3.69429596
91fatty acid beta-oxidation (GO:0006635)3.68124804
92low-density lipoprotein particle remodeling (GO:0034374)3.67344217
93cofactor catabolic process (GO:0051187)3.66358141
94carnitine metabolic process (GO:0009437)3.66006847
95fatty acid oxidation (GO:0019395)3.65939704
96drug metabolic process (GO:0017144)3.65235044
97monocarboxylic acid catabolic process (GO:0072329)3.62847268
98valine metabolic process (GO:0006573)3.58151778
99lipid oxidation (GO:0034440)3.58119827
100regulation of bile acid biosynthetic process (GO:0070857)3.57870520
101pyridine nucleotide biosynthetic process (GO:0019363)3.57512087
102nicotinamide nucleotide biosynthetic process (GO:0019359)3.57512087
103negative regulation of protein activation cascade (GO:2000258)3.57317832
104fibrinolysis (GO:0042730)3.56847079
105cholesterol efflux (GO:0033344)3.55393522
106response to nitrosative stress (GO:0051409)3.54274735
107positive regulation of triglyceride lipase activity (GO:0061365)3.52413020
108positive regulation of lipoprotein lipase activity (GO:0051006)3.52413020
109NAD biosynthetic process (GO:0009435)3.51889736
110plasma lipoprotein particle organization (GO:0071827)3.51132355
111fatty acid catabolic process (GO:0009062)3.50756278
112flavonoid metabolic process (GO:0009812)3.50165475
113S-adenosylmethionine metabolic process (GO:0046500)3.49013498
114plasma lipoprotein particle assembly (GO:0034377)3.47979457
115regulation of cholesterol homeostasis (GO:2000188)3.47968573
116phospholipid homeostasis (GO:0055091)3.47602005
117regulation of plasminogen activation (GO:0010755)3.44263134
118negative regulation of lipase activity (GO:0060192)3.40527811
119heme transport (GO:0015886)3.36147189
120diacylglycerol metabolic process (GO:0046339)3.27768304
121cholesterol homeostasis (GO:0042632)3.27563084
122cytolysis (GO:0019835)3.27234628
123sterol homeostasis (GO:0055092)3.20593862
124protein activation cascade (GO:0072376)3.19803734
125alkaloid metabolic process (GO:0009820)3.16813421
126peptidyl-glutamic acid modification (GO:0018200)3.14436944
127polyketide metabolic process (GO:0030638)3.13944873
128doxorubicin metabolic process (GO:0044598)3.13944873
129daunorubicin metabolic process (GO:0044597)3.13944873
130protein-lipid complex subunit organization (GO:0071825)3.13372206
131water-soluble vitamin biosynthetic process (GO:0042364)3.12410165
132acute-phase response (GO:0006953)3.11334513
133regulation of humoral immune response (GO:0002920)3.10640646
134regulation of lipoprotein particle clearance (GO:0010984)3.10270547
135glycerol metabolic process (GO:0006071)3.08781563
136negative regulation of blood coagulation (GO:0030195)3.07841587
137negative regulation of hemostasis (GO:1900047)3.07841587
138negative regulation of complement activation (GO:0045916)3.05683063

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1* RXR_22158963_ChIP-Seq_LIVER_Mouse8.27002670
2* PPARA_22158963_ChIP-Seq_LIVER_Mouse7.09910155
3EGR1_23403033_ChIP-Seq_LIVER_Mouse6.90745551
4LXR_22158963_ChIP-Seq_LIVER_Mouse6.21495497
5CEBPA_23403033_ChIP-Seq_LIVER_Mouse5.10528900
6PPARG_19300518_ChIP-PET_3T3-L1_Mouse4.88153402
7FOXO1_23066095_ChIP-Seq_LIVER_Mouse4.85162896
8CEBPB_23403033_ChIP-Seq_LIVER_Mouse4.29446363
9NR1I2_20693526_ChIP-Seq_LIVER_Mouse3.64538673
10ZNF274_21170338_ChIP-Seq_K562_Hela2.75646473
11VDR_22108803_ChIP-Seq_LS180_Human2.71397397
12HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.66312375
13IGF1R_20145208_ChIP-Seq_DFB_Human2.42060540
14HNF4A_19761587_ChIP-ChIP_CACO-2_Human2.41729313
15GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.39585239
16TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse2.28215937
17ESR1_17901129_ChIP-ChIP_LIVER_Mouse11.7435772
18TCF7L2_21901280_ChIP-Seq_H4IIE_Rat1.98253179
19GBX2_23144817_ChIP-Seq_PC3_Human1.93762494
20HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.83769326
21* FLI1_27457419_Chip-Seq_LIVER_Mouse1.79808194
22GABP_17652178_ChIP-ChIP_JURKAT_Human1.72931471
23* PCGF2_27294783_Chip-Seq_NPCs_Mouse1.69014049
24* PCGF2_27294783_Chip-Seq_ESCs_Mouse1.60523527
25POU3F2_20337985_ChIP-ChIP_501MEL_Human1.60240132
26GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.56908021
27EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.55970982
28CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.50463356
29TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.49704471
30ZFP57_27257070_Chip-Seq_ESCs_Mouse1.47426496
31ETV2_25802403_ChIP-Seq_MESCs_Mouse1.46716947
32FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.45845087
33* HNF4A_19822575_ChIP-Seq_HepG2_Human1.45589187
34* NFE2_27457419_Chip-Seq_LIVER_Mouse1.44118100
35CLOCK_20551151_ChIP-Seq_293T_Human1.42853215
36FOXA2_19822575_ChIP-Seq_HepG2_Human1.42408452
37FOXA1_25329375_ChIP-Seq_VCAP_Human1.38266412
38FOXA1_27270436_Chip-Seq_PROSTATE_Human1.38266412
39ER_23166858_ChIP-Seq_MCF-7_Human1.37883966
40CTBP1_25329375_ChIP-Seq_LNCAP_Human1.37544773
41STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.36241461
42BCAT_22108803_ChIP-Seq_LS180_Human1.36239210
43HTT_18923047_ChIP-ChIP_STHdh_Human1.35473900
44* SUZ12_27294783_Chip-Seq_NPCs_Mouse1.35312810
45GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.33866938
46TAF15_26573619_Chip-Seq_HEK293_Human1.31795138
47NANOG_19829295_ChIP-Seq_ESCs_Human1.30931015
48SOX2_19829295_ChIP-Seq_ESCs_Human1.30931015
49RXRA_24833708_ChIP-Seq_LIVER_Mouse1.28281680
50EST1_17652178_ChIP-ChIP_JURKAT_Human1.26197738
51NOTCH1_21737748_ChIP-Seq_TLL_Human1.25102097
52KAP1_22055183_ChIP-Seq_ESCs_Mouse1.24538760
53CTBP2_25329375_ChIP-Seq_LNCAP_Human1.21081976
54P300_19829295_ChIP-Seq_ESCs_Human1.20384593
55CBP_20019798_ChIP-Seq_JUKART_Human1.19290619
56IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.19290619
57GATA1_22025678_ChIP-Seq_K562_Human1.17966613
58GATA3_21878914_ChIP-Seq_MCF-7_Human1.17791607
59MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.17699748
60MYC_18940864_ChIP-ChIP_HL60_Human1.17433442
61UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.16368883
62* EZH2_27294783_Chip-Seq_NPCs_Mouse1.15645485
63FUS_26573619_Chip-Seq_HEK293_Human1.15512497
64E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.14922283
65ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.14435712
66PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.12640922
67NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.12482001
68ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.11823719
69PIAS1_25552417_ChIP-Seq_VCAP_Human1.11386007
70FOXA1_21572438_ChIP-Seq_LNCaP_Human1.11200551
71TCF4_22108803_ChIP-Seq_LS180_Human1.09647610
72KLF5_20875108_ChIP-Seq_MESCs_Mouse1.09446585
73TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.04983422
74EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.03563519
75NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.02473352
76AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.01849781
77JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.00204924
78TP53_22573176_ChIP-Seq_HFKS_Human0.99977879
79STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.98689687
80* CRX_20693478_ChIP-Seq_RETINA_Mouse0.98660362
81* NANOG_20526341_ChIP-Seq_ESCs_Human0.98102446
82STAT3_23295773_ChIP-Seq_U87_Human0.97531982
83SOX2_27498859_Chip-Seq_STOMACH_Mouse0.96583871
84* CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.95784910
85ERA_21632823_ChIP-Seq_H3396_Human0.95538922
86SALL1_21062744_ChIP-ChIP_HESCs_Human0.95237780
87STAT3_1855785_ChIP-Seq_MESCs_Mouse0.93872815
88FOXH1_21741376_ChIP-Seq_ESCs_Human0.93488199
89GATA4_25053715_ChIP-Seq_YYC3_Human0.92759940
90AR_21909140_ChIP-Seq_LNCAP_Human0.92428016
91* SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse0.91539753
92* MYC_19829295_ChIP-Seq_ESCs_Human0.91276801
93MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.90786440
94EZH2_22144423_ChIP-Seq_EOC_Human0.90138883
95AR_25329375_ChIP-Seq_VCAP_Human0.89207808
96* STAT3_18555785_Chip-Seq_ESCs_Mouse0.88828039
97SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.88087332
98IRF1_21803131_ChIP-Seq_MONOCYTES_Human0.87889131
99AUTS2_25519132_ChIP-Seq_293T-REX_Human0.87096421
100PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.86485768
101CEBPA_26348894_ChIP-Seq_LIVER_Mouse0.86049813
102ETV1_20927104_ChIP-Seq_GIST48_Human0.86048211
103PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.83748750
104NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.83298991
105RARA_24833708_ChIP-Seq_LIVER_Mouse0.77951782
106SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.77524184
107ESR1_21235772_ChIP-Seq_MCF-7_Human0.77370397
108IRF8_22096565_ChIP-ChIP_GC-B_Human0.74567454
109ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.73351624
110RARG_19884340_ChIP-ChIP_MEFs_Mouse0.72648606
111THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.67936653
112SALL4_18804426_ChIP-ChIP_XEN_Mouse0.66988686
113RARB_24833708_ChIP-Seq_LIVER_Mouse0.66402999
114AR_20517297_ChIP-Seq_VCAP_Human0.66230775
115CEBPB_22108803_ChIP-Seq_LS180_Human0.65567192
116RAD21_21589869_ChIP-Seq_MESCs_Mouse0.65561034
117CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.65421565
118BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.65374614
119* SRF_21415370_ChIP-Seq_HL-1_Mouse0.64643147
120ZNF263_19887448_ChIP-Seq_K562_Human0.64307000
121AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.63325323
122KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human0.62831827
123* NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.62380398
124ESET_19884257_ChIP-Seq_ESCs_Mouse0.62271188
125ESR1_15608294_ChIP-ChIP_MCF-7_Human0.61197794
126FOXA1_26743006_Chip-Seq_LNCaP-abl_Human0.60564091
127STAT1_17558387_ChIP-Seq_HELA_Human0.59537353
128FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.56430120
129ESR2_21235772_ChIP-Seq_MCF-7_Human0.55872079
130GATA6_25053715_ChIP-Seq_YYC3_Human0.55742301
131PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.55129099
132ERG_20517297_ChIP-Seq_VCAP_Human0.54783081
133FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.51669889
134CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse0.51307801
135RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.50532418
136SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.50460910
137P53_21459846_ChIP-Seq_SAOS-2_Human0.50359935
138* E2F1_18555785_ChIP-Seq_MESCs_Mouse0.48414391
139FOXA1_25552417_ChIP-Seq_VCAP_Human0.47900456
140STAT3_19079543_ChIP-ChIP_MESCs_Mouse0.47468001
141GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.47462642
142MYC_19915707_ChIP-ChIP_AK7_Human0.46874899
143* PPARG_20887899_ChIP-Seq_3T3-L1_Mouse0.46798829
144POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.46615897
145CBP_21632823_ChIP-Seq_H3396_Human0.45797595
146EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse0.45610789
147IRF1_19129219_ChIP-ChIP_H3396_Human0.45116551
148TAF2_19829295_ChIP-Seq_ESCs_Human0.43799637
149FOXH1_21741376_ChIP-Seq_EPCs_Human0.43230261
150SOX2_22085726_ChIP-Seq_NPCs_Mouse0.43060714
151SPI1_26923725_Chip-Seq_HPCs_Mouse0.42165301
152TET1_21451524_ChIP-Seq_MESCs_Mouse0.41935666
153PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.41457004
154SOX2_18692474_ChIP-Seq_MEFs_Mouse0.41378680
155BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.39587441
156CDX2_22108803_ChIP-Seq_LS180_Human0.39388217
157* OCT4_20526341_ChIP-Seq_ESCs_Human0.39274324
158RAC3_21632823_ChIP-Seq_H3396_Human0.39178645
159* PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.39005570
160Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.38244641
161CSB_26484114_Chip-Seq_FIBROBLAST_Human0.37784072
162LXR_22292898_ChIP-Seq_THP-1_Human0.37696347
163EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.37495700
164NCOR_22424771_ChIP-Seq_293T_Human0.37338580
165GATA3_24758297_ChIP-Seq_MCF-7_Human0.37214156
166* SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.36873023
167SOX3_22085726_ChIP-Seq_MUSCLE_Mouse0.36818765

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002139_abnormal_hepatobiliary_system8.23587015
2MP0005360_urolithiasis7.86143136
3MP0005085_abnormal_gallbladder_physiolo6.07390178
4MP0005365_abnormal_bile_salt5.94230187
5MP0008875_abnormal_xenobiotic_pharmacok5.00431589
6MP0003806_abnormal_nucleotide_metabolis4.43831277
7MP0003252_abnormal_bile_duct3.69792432
8MP0005332_abnormal_amino_acid3.25330233
9MP0010329_abnormal_lipoprotein_level3.16401253
10MP0003195_calcinosis3.09746660
11MP0009840_abnormal_foam_cell2.91898843
12MP0005083_abnormal_biliary_tract2.83393741
13MP0001666_abnormal_nutrient_absorption2.59845966
14MP0004019_abnormal_vitamin_homeostasis2.55531003
15MP0003122_maternal_imprinting2.24711160
16MP0002138_abnormal_hepatobiliary_system2.23155444
17MP0000609_abnormal_liver_physiology2.01647385
18MP0003191_abnormal_cellular_cholesterol2.01568527
19MP0006292_abnormal_olfactory_placode1.97392457
20MP0002118_abnormal_lipid_homeostasis1.95674747
21MP0005319_abnormal_enzyme/_coenzyme1.86004463
22MP0005451_abnormal_body_composition1.85557603
23MP0001764_abnormal_homeostasis1.82238328
24MP0009643_abnormal_urine_homeostasis1.75381584
25MP0003868_abnormal_feces_composition1.73795141
26MP0003186_abnormal_redox_activity1.70343046
27MP0005584_abnormal_enzyme/coenzyme_acti1.59915931
28MP0009697_abnormal_copulation1.45271296
29MP0005551_abnormal_eye_electrophysiolog1.38772027
30MP0005636_abnormal_mineral_homeostasis1.38335135
31MP0005379_endocrine/exocrine_gland_phen1.20717468
32MP0008877_abnormal_DNA_methylation1.20326989
33MP0003656_abnormal_erythrocyte_physiolo1.17755592
34MP0006036_abnormal_mitochondrial_physio1.17677192
35MP0000598_abnormal_liver_morphology1.17337106
36MP0004043_abnormal_pH_regulation1.14336403
37MP0003011_delayed_dark_adaptation1.13015142
38MP0002938_white_spotting1.12690518
39MP0003136_yellow_coat_color1.11681165
40MP0005408_hypopigmentation1.09310601
41MP0003121_genomic_imprinting1.09185745
42MP0003718_maternal_effect1.07832585
43MP0005647_abnormal_sex_gland1.06092000
44MP0002638_abnormal_pupillary_reflex1.05820995
45MP0001986_abnormal_taste_sensitivity1.04419090
46MP0005220_abnormal_exocrine_pancreas1.02744480
47MP0004142_abnormal_muscle_tone1.00978716
48MP0005084_abnormal_gallbladder_morpholo0.99794935
49MP0001756_abnormal_urination0.98142997
50MP0001324_abnormal_eye_pigmentation0.97676469
51MP0009763_increased_sensitivity_to0.92637797
52MP0009764_decreased_sensitivity_to0.92629381
53MP0002132_abnormal_respiratory_system0.91247362
54MP0009642_abnormal_blood_homeostasis0.89477917
55MP0003705_abnormal_hypodermis_morpholog0.88400595
56MP0008469_abnormal_protein_level0.87057249
57MP0005670_abnormal_white_adipose0.86967063
58MP0000372_irregular_coat_pigmentation0.86782205
59MP0002876_abnormal_thyroid_physiology0.83419114
60MP0002136_abnormal_kidney_physiology0.83026859
61MP0002909_abnormal_adrenal_gland0.82258567
62MP0005376_homeostasis/metabolism_phenot0.79607984
63MP0000604_amyloidosis0.78792056
64MP0005645_abnormal_hypothalamus_physiol0.78637994
65MP0002078_abnormal_glucose_homeostasis0.78526763
66MP0005395_other_phenotype0.77123476
67MP0008789_abnormal_olfactory_epithelium0.77033630
68MP0004133_heterotaxia0.76653691
69MP0003878_abnormal_ear_physiology0.76143579
70MP0005377_hearing/vestibular/ear_phenot0.76143579
71MP0002163_abnormal_gland_morphology0.74671404
72MP0009765_abnormal_xenobiotic_induced0.74553815
73MP0010368_abnormal_lymphatic_system0.74295234
74MP0005266_abnormal_metabolism0.71133011
75MP0005410_abnormal_fertilization0.70296883
76MP0001765_abnormal_ion_homeostasis0.69936192
77MP0001661_extended_life_span0.69118544
78MP0006276_abnormal_autonomic_nervous0.69063469
79MP0001984_abnormal_olfaction0.68662409
80MP0005535_abnormal_body_temperature0.68543098
81MP0006035_abnormal_mitochondrial_morpho0.64629367
82MP0005195_abnormal_posterior_eye0.64616242
83MP0001529_abnormal_vocalization0.63836892
84MP0003950_abnormal_plasma_membrane0.63598762
85MP0001293_anophthalmia0.63212859
86MP0000566_synostosis0.63137278
87MP0003787_abnormal_imprinting0.61653107
88MP0002971_abnormal_brown_adipose0.60144428
89MP0003879_abnormal_hair_cell0.58389640
90MP0005334_abnormal_fat_pad0.57984155
91MP0005253_abnormal_eye_physiology0.57282463
92MP0000639_abnormal_adrenal_gland0.56932129
93MP0005075_abnormal_melanosome_morpholog0.55784942
94MP0002160_abnormal_reproductive_system0.55641454
95MP0001968_abnormal_touch/_nociception0.55492066
96MP0005389_reproductive_system_phenotype0.54914156
97MP0002736_abnormal_nociception_after0.54306273
98MP0005058_abnormal_lysosome_morphology0.53944767
99MP0002928_abnormal_bile_duct0.53109460
100MP0002102_abnormal_ear_morphology0.51880626
101MP0009053_abnormal_anal_canal0.51050207
102MP0002254_reproductive_system_inflammat0.50594889
103MP0005167_abnormal_blood-brain_barrier0.49732314
104MP0005646_abnormal_pituitary_gland0.49410512
105MP0004264_abnormal_extraembryonic_tissu0.48982493
106MP0003638_abnormal_response/metabolism_0.48231547
107MP0001485_abnormal_pinna_reflex0.47781323
108MP0002090_abnormal_vision0.47615824
109MP0003329_amyloid_beta_deposits0.47351976
110MP0004782_abnormal_surfactant_physiolog0.46485998
111MP0002277_abnormal_respiratory_mucosa0.46356772
112MP0003698_abnormal_male_reproductive0.45151265
113MP0001501_abnormal_sleep_pattern0.44908869
114MP0003953_abnormal_hormone_level0.44794888
115MP0008873_increased_physiological_sensi0.43864270
116MP0009672_abnormal_birth_weight0.41721762
117MP0000230_abnormal_systemic_arterial0.40902412
118MP0005666_abnormal_adipose_tissue0.40612921
119MP0004130_abnormal_muscle_cell0.39750067
120MP0002168_other_aberrant_phenotype0.38737529
121MP0000538_abnormal_urinary_bladder0.38697839
122MP0005448_abnormal_energy_balance0.38609857
123MP0002135_abnormal_kidney_morphology0.38319821
124MP0003699_abnormal_female_reproductive0.37842938
125MP0003724_increased_susceptibility_to0.36694213
126MP0008872_abnormal_physiological_respon0.36145129
127MP0000579_abnormal_nail_morphology0.36111548
128MP0003646_muscle_fatigue0.35417173
129MP0002837_dystrophic_cardiac_calcinosis0.35062406
130MP0005464_abnormal_platelet_physiology0.33625143
131MP0001944_abnormal_pancreas_morphology0.32166188
132MP0003690_abnormal_glial_cell0.31886947
133MP0008874_decreased_physiological_sensi0.30967969
134MP0002970_abnormal_white_adipose0.30695293
135MP0002796_impaired_skin_barrier0.29848985
136MP0001119_abnormal_female_reproductive0.28965658
137MP0001845_abnormal_inflammatory_respons0.27595517
138MP0009384_cardiac_valve_regurgitation0.27206926
139MP0004147_increased_porphyrin_level0.26420245
140MP0009115_abnormal_fat_cell0.25886353
141MP0005166_decreased_susceptibility_to0.24800753
142MP0002269_muscular_atrophy0.24619642
143MP0003436_decreased_susceptibility_to0.23314498
144MP0003075_altered_response_to0.21980490
145MP0003959_abnormal_lean_body0.21552436

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of aromatic amino acid family metabolism (HP:0004338)7.22409379
2Intrahepatic cholestasis (HP:0001406)6.77080903
3Deep venous thrombosis (HP:0002625)6.37659507
4Abnormality of monocarboxylic acid metabolism (HP:0010996)6.11615947
5Hypobetalipoproteinemia (HP:0003563)5.66188628
6Xanthomatosis (HP:0000991)5.64444116
7Prolonged partial thromboplastin time (HP:0003645)5.53160674
8Hyperglycinemia (HP:0002154)4.72890898
9Hyperglycinuria (HP:0003108)4.72123378
10Hyperammonemia (HP:0001987)4.70969514
11Hyperlipoproteinemia (HP:0010980)4.68378535
12Ketosis (HP:0001946)4.62716133
13Abnormality of glutamine family amino acid metabolism (HP:0010902)4.56416715
14Abnormality of glycine metabolism (HP:0010895)4.46745177
15Abnormality of serine family amino acid metabolism (HP:0010894)4.46745177
16Complement deficiency (HP:0004431)4.45090284
17Abnormality of aspartate family amino acid metabolism (HP:0010899)4.39971923
18Abnormality of sulfur amino acid metabolism (HP:0004339)4.31569859
19Hypolipoproteinemia (HP:0010981)4.12873912
20Joint hemorrhage (HP:0005261)4.07477385
21Abnormality of methionine metabolism (HP:0010901)4.05407928
22Fat malabsorption (HP:0002630)3.94585413
23Hypoglycemic coma (HP:0001325)3.93727331
24Abnormality of the common coagulation pathway (HP:0010990)3.85331389
25Gout (HP:0001997)3.83128867
26Abnormality of pyrimidine metabolism (HP:0004353)3.82333332
27Abnormality of fatty-acid metabolism (HP:0004359)3.77562481
28Epidermoid cyst (HP:0200040)3.76892725
29Abnormality of the level of lipoprotein cholesterol (HP:0010979)3.73384050
30Ketoacidosis (HP:0001993)3.64111359
31Abnormality of nucleobase metabolism (HP:0010932)3.59795603
32Delayed CNS myelination (HP:0002188)3.50092392
33Abnormality of purine metabolism (HP:0004352)3.48526739
34Hypoalphalipoproteinemia (HP:0003233)3.48163140
35Abnormality of long-chain fatty-acid metabolism (HP:0010964)3.46742818
36Abnormality of the intrinsic pathway (HP:0010989)3.42912921
37Abnormality of serum amino acid levels (HP:0003112)3.37343240
38Conjugated hyperbilirubinemia (HP:0002908)3.35437393
39Hyperbilirubinemia (HP:0002904)3.26978285
40Abnormality of complement system (HP:0005339)3.16718570
41Generalized aminoaciduria (HP:0002909)3.16619142
42Dicarboxylic aciduria (HP:0003215)3.09152029
43Abnormality of dicarboxylic acid metabolism (HP:0010995)3.09152029
44Metabolic acidosis (HP:0001942)3.08898798
45Steatorrhea (HP:0002570)3.06905273
46Lethargy (HP:0001254)3.02812876
47Hypercholesterolemia (HP:0003124)2.96916036
48Proximal tubulopathy (HP:0000114)2.87519477
49Hepatocellular carcinoma (HP:0001402)2.86493374
50Bile duct proliferation (HP:0001408)2.83528407
51Abnormal biliary tract physiology (HP:0012439)2.83528407
52Vascular calcification (HP:0004934)2.75684084
53Cerebral edema (HP:0002181)2.69532546
54Malnutrition (HP:0004395)2.67669848
55Increased purine levels (HP:0004368)2.67654055
56Hyperuricemia (HP:0002149)2.67654055
57Pancreatic cysts (HP:0001737)2.64588993
58Alkalosis (HP:0001948)2.59227111
59Spastic diplegia (HP:0001264)2.53691151
60Irritability (HP:0000737)2.51536846
61Abnormality of urine glucose concentration (HP:0011016)2.51114256
62Glycosuria (HP:0003076)2.51114256
63Spontaneous abortion (HP:0005268)2.48778745
64Increased serum pyruvate (HP:0003542)2.48048228
65Vomiting (HP:0002013)2.44535632
66Acute encephalopathy (HP:0006846)2.43291363
67Abnormality of the renal cortex (HP:0011035)2.42886677
68Cardiovascular calcification (HP:0011915)2.41134456
69Pancreatic fibrosis (HP:0100732)2.40300164
70Late onset (HP:0003584)2.38281070
71Myocardial infarction (HP:0001658)2.38185912
72Neonatal onset (HP:0003623)2.38144212
73True hermaphroditism (HP:0010459)2.36515812
74Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.36378157
75Abnormality of alanine metabolism (HP:0010916)2.36378157
76Hyperalaninemia (HP:0003348)2.36378157
77Hypoglycemic seizures (HP:0002173)2.35196784
78Hypochromic microcytic anemia (HP:0004840)2.33650563
79Enlarged kidneys (HP:0000105)2.32503306
80Arthropathy (HP:0003040)2.31487719
81Systemic lupus erythematosus (HP:0002725)2.31371674
82Pancreatitis (HP:0001733)2.25655822
83Skin nodule (HP:0200036)2.24823543
84Rickets (HP:0002748)2.24664730
85Reduced antithrombin III activity (HP:0001976)2.21843441
86Brushfield spots (HP:0001088)2.21720351
87Hypothermia (HP:0002045)2.20815561
88Sensorimotor neuropathy (HP:0007141)2.20003776
89Abnormal gallbladder morphology (HP:0012437)2.15937470
90Hydroxyprolinuria (HP:0003080)2.15265505
91Abnormality of proline metabolism (HP:0010907)2.15265505
92Opisthotonus (HP:0002179)2.14477873
93Cholecystitis (HP:0001082)2.13260592
94Abnormal gallbladder physiology (HP:0012438)2.13260592
95Abnormal enzyme/coenzyme activity (HP:0012379)2.11897732
96Cholelithiasis (HP:0001081)2.09143304
97Osteomalacia (HP:0002749)2.07687525
98Acute necrotizing encephalopathy (HP:0006965)2.06577932
99Potter facies (HP:0002009)2.05160912
100Facial shape deformation (HP:0011334)2.05160912
101Acanthocytosis (HP:0001927)2.04444695
102Abnormality of midbrain morphology (HP:0002418)2.03222493
103Molar tooth sign on MRI (HP:0002419)2.03222493
104Abnormality of glycolysis (HP:0004366)2.02152674
105Nausea (HP:0002018)2.00392083
106Glomerulonephritis (HP:0000099)1.99659008
107Chronic hepatic failure (HP:0100626)1.98752179
108Abnormal cartilage morphology (HP:0002763)1.97709688
109Pancreatic islet-cell hyperplasia (HP:0004510)1.96960247
110Hyperinsulinemic hypoglycemia (HP:0000825)1.96824093
111Fair hair (HP:0002286)1.96519044
112Mitral stenosis (HP:0001718)1.94291897
113Congenital stationary night blindness (HP:0007642)1.92300897
114Renal cortical cysts (HP:0000803)1.91322824
115Abnormality of alkaline phosphatase activity (HP:0004379)1.89566273
116Nephrolithiasis (HP:0000787)1.89425079
117Hypophosphatemic rickets (HP:0004912)1.87895702
118Mitochondrial inheritance (HP:0001427)1.87833751
119Lipid accumulation in hepatocytes (HP:0006561)1.86937024
120Increased CSF lactate (HP:0002490)1.86347050
121Abnormality of transition element cation homeostasis (HP:0011030)1.85760413
122Thrombophlebitis (HP:0004418)1.85313847
123Hepatic necrosis (HP:0002605)1.84413377
124Esophageal varix (HP:0002040)1.83848399
125Hyperphosphaturia (HP:0003109)1.82932903
126Elevated alkaline phosphatase (HP:0003155)1.82769873
127Gingival bleeding (HP:0000225)1.82305722
128Elevated hepatic transaminases (HP:0002910)1.81820634
129Abnormality of the gallbladder (HP:0005264)1.81065415
130Abnormal mitochondria in muscle tissue (HP:0008316)1.80652495
131Abnormality of vitamin metabolism (HP:0100508)1.79717800
132Renal Fanconi syndrome (HP:0001994)1.79324445
133Methylmalonic acidemia (HP:0002912)1.78163243
134Hemorrhage of the eye (HP:0011885)1.75488337
135Nephritis (HP:0000123)1.73732767
136Abnormal urine phosphate concentration (HP:0012599)1.71510304
137Pendular nystagmus (HP:0012043)1.70877965
138Retrobulbar optic neuritis (HP:0100654)1.70452790
139Optic neuritis (HP:0100653)1.70452790
140Increased hepatocellular lipid droplets (HP:0006565)1.69184111

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BCKDK8.10633954
2ERN13.84545954
3FGFR43.62941613
4ZAK3.54793660
5TAOK33.49991755
6TXK3.42776291
7ERBB43.37680707
8SIK13.32786528
9TRIM282.68940802
10STK38L2.66447509
11NUAK12.65296410
12BMPR1B2.53790553
13WNK42.52217536
14INSRR2.43281234
15TLK12.41600429
16ADRBK22.38456829
17WNK32.22899348
18GRK12.21525492
19FLT32.14906063
20MAP4K22.11354990
21LATS12.11330522
22PIK3CA2.06965606
23MAP3K41.92131065
24MAPK111.87923991
25BCR1.86408196
26VRK11.83699624
27MAP2K41.72299950
28MST1R1.71433065
29PKN21.71364651
30ABL21.70531751
31OXSR11.68136524
32MUSK1.63759439
33PINK11.63521187
34PIK3CG1.61384283
35CASK1.58360855
36SIK21.51104137
37MAP3K61.49910337
38PRKCG1.44280288
39MAPK131.42821080
40DYRK21.38841652
41TYK21.33248343
42NEK91.25617208
43VRK21.22304717
44TRIB31.14726428
45NEK11.14435196
46PRKAA21.09876713
47KDR1.07897996
48RIPK11.06035658
49STK161.04149929
50MAP2K31.01252782
51JAK21.00197634
52MAP3K30.97492024
53PDK40.92867726
54PDK30.92867726
55MAPK150.92827325
56PRKCE0.90690998
57GRK60.90268752
58ACVR1B0.89307981
59EIF2AK10.89226640
60PRKCI0.88214113
61PTK60.86830009
62MAP2K70.86390596
63MAP3K120.86380187
64FRK0.85460908
65PRKCQ0.81911387
66MAP3K70.80869613
67MET0.78555461
68PRKACA0.77851525
69IRAK30.76535184
70EPHA40.76438245
71MAP3K110.76242373
72NME10.75267291
73TNIK0.74357687
74MST40.73652470
75PRKAA10.72247415
76CAMKK20.71257309
77TIE10.70709001
78PLK30.70592486
79LATS20.69727674
80TYRO30.68536119
81MAP2K60.65928712
82TTK0.63879542
83MAPKAPK30.63706141
84MAPK40.63372680
85TBK10.62382797
86SGK2230.61292113
87SGK4940.61292113
88ERBB20.60644189
89PRKG10.59864904
90DYRK1B0.59718025
91NME20.59451855
92PRKCZ0.59327918
93PAK30.59316454
94BRSK20.59025711
95BRAF0.58815837
96ADRBK10.58656381
97IKBKB0.58069798
98ITK0.57291073
99GSK3A0.57040604
100CSNK1G10.55793880
101PBK0.53626521
102CSNK2A10.53489322
103FGFR30.53081315
104NTRK20.52831259
105MAP3K50.52774859
106MAPK120.51230017
107PRKACG0.49424909
108MAP3K140.48926168
109STK390.48899069
110CDK40.47506388
111PTK20.47173405
112EIF2AK30.46824943
113MAP3K130.46137851
114SGK20.45943825
115PRKCA0.45444779
116KSR20.44992364
117DAPK20.44363391
118DAPK10.44303545
119CSNK1D0.44007937
120DYRK30.43986051
121CAMK2G0.43823075
122CDK60.43741741
123SGK30.43070382
124RPS6KA50.41876289
125NEK20.41753695
126CAMK10.41727589
127PRKACB0.41629618
128PDK20.41568108
129EPHB20.41510945
130CDK80.41310049
131MOS0.39497077
132MAP3K100.38876110
133CSNK1E0.37115155
134ERBB30.36954308
135CSNK2A20.36352636
136PLK10.36257536
137JAK10.36222405
138MAP3K80.36002500
139STK30.35832403
140PRKCB0.35327700
141CSF1R0.33383182
142MAPKAPK50.33260902
143CSNK1G30.33042041
144PHKG10.32842855
145PHKG20.32842855
146FGFR10.32732870
147TAOK20.32555753
148TEC0.32188599
149EPHB10.31389166
150PDPK10.31262321
151TGFBR20.30937501
152IKBKE0.30651627
153MAP2K10.28568705
154MAP2K20.28252220
155PLK40.26388110
156MELK0.25043556
157IGF1R0.24612442
158MTOR0.24531431
159STK380.23385179
160CSK0.23222917
161FGFR20.22639636
162LRRK20.22638837
163CSNK1G20.19481631

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary bile acid biosynthesis_Homo sapiens_hsa001204.15970871
2Ascorbate and aldarate metabolism_Homo sapiens_hsa000533.56278813
3Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004003.07203745
4Nitrogen metabolism_Homo sapiens_hsa009102.94828260
5Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006302.82275102
6Arginine biosynthesis_Homo sapiens_hsa002202.77659610
7Tryptophan metabolism_Homo sapiens_hsa003802.69559813
8Glycine, serine and threonine metabolism_Homo sapiens_hsa002602.68758513
9Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.64938366
10Fatty acid degradation_Homo sapiens_hsa000712.50206625
11Pentose and glucuronate interconversions_Homo sapiens_hsa000402.43280278
12Butanoate metabolism_Homo sapiens_hsa006502.41389503
13Complement and coagulation cascades_Homo sapiens_hsa046102.29377843
14* Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010402.27600776
15Propanoate metabolism_Homo sapiens_hsa006402.21344162
16* Peroxisome_Homo sapiens_hsa041462.18001128
17Drug metabolism - cytochrome P450_Homo sapiens_hsa009822.09555271
18Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.96572433
19Histidine metabolism_Homo sapiens_hsa003401.90617131
20Chemical carcinogenesis_Homo sapiens_hsa052041.85523124
21Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.83906196
22beta-Alanine metabolism_Homo sapiens_hsa004101.81789460
23Steroid hormone biosynthesis_Homo sapiens_hsa001401.79525960
24Drug metabolism - other enzymes_Homo sapiens_hsa009831.77562603
252-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.75142349
26Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.71389776
27Selenocompound metabolism_Homo sapiens_hsa004501.69126698
28PPAR signaling pathway_Homo sapiens_hsa033201.68389406
29Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.68223738
30* Fatty acid metabolism_Homo sapiens_hsa012121.65691178
31Pyruvate metabolism_Homo sapiens_hsa006201.63717471
32Retinol metabolism_Homo sapiens_hsa008301.59188851
33Folate biosynthesis_Homo sapiens_hsa007901.54035249
34Cyanoamino acid metabolism_Homo sapiens_hsa004601.53500890
35Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.52475130
36Caffeine metabolism_Homo sapiens_hsa002321.51032829
37Sulfur metabolism_Homo sapiens_hsa009201.50290525
38Phenylalanine metabolism_Homo sapiens_hsa003601.48940137
39Cysteine and methionine metabolism_Homo sapiens_hsa002701.45822354
40Bile secretion_Homo sapiens_hsa049761.38563609
41Staphylococcus aureus infection_Homo sapiens_hsa051501.34181988
42Tyrosine metabolism_Homo sapiens_hsa003501.31670051
43Biosynthesis of amino acids_Homo sapiens_hsa012301.30256774
44Starch and sucrose metabolism_Homo sapiens_hsa005001.29875073
45Fatty acid elongation_Homo sapiens_hsa000621.29275380
46Carbon metabolism_Homo sapiens_hsa012001.27686413
47Maturity onset diabetes of the young_Homo sapiens_hsa049501.19894143
48Arginine and proline metabolism_Homo sapiens_hsa003301.16983857
49Steroid biosynthesis_Homo sapiens_hsa001001.14850589
50Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.14180546
51Sulfur relay system_Homo sapiens_hsa041221.09917779
52Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.04607787
53Fat digestion and absorption_Homo sapiens_hsa049751.03501708
54Vitamin digestion and absorption_Homo sapiens_hsa049771.01649741
55Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.00882701
56ABC transporters_Homo sapiens_hsa020100.99024640
57Vitamin B6 metabolism_Homo sapiens_hsa007500.97968559
58Glutathione metabolism_Homo sapiens_hsa004800.96020972
59One carbon pool by folate_Homo sapiens_hsa006700.94871392
60Lysine degradation_Homo sapiens_hsa003100.87859486
61Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.86957482
62Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.84920025
63Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.80566377
64Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.79351594
65Glycerolipid metabolism_Homo sapiens_hsa005610.72606522
66Pentose phosphate pathway_Homo sapiens_hsa000300.67461732
67Parkinsons disease_Homo sapiens_hsa050120.64647326
68Metabolic pathways_Homo sapiens_hsa011000.57545864
69Proteasome_Homo sapiens_hsa030500.47687422
70Phototransduction_Homo sapiens_hsa047440.40074866
71RNA polymerase_Homo sapiens_hsa030200.39717663
72alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.37934064
73Fructose and mannose metabolism_Homo sapiens_hsa000510.36515202
74Galactose metabolism_Homo sapiens_hsa000520.33646510
75Huntingtons disease_Homo sapiens_hsa050160.33544739
76Linoleic acid metabolism_Homo sapiens_hsa005910.31781621
77Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.31507502
78Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.30895654
79Homologous recombination_Homo sapiens_hsa034400.30284796
80Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.26992050
81Fatty acid biosynthesis_Homo sapiens_hsa000610.26500998
82Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.25489443
83Alzheimers disease_Homo sapiens_hsa050100.25269533
84Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.17604218
85RNA degradation_Homo sapiens_hsa030180.15891187
86Prion diseases_Homo sapiens_hsa050200.15172940
87Ribosome_Homo sapiens_hsa030100.14601307
88Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.13611822
89N-Glycan biosynthesis_Homo sapiens_hsa005100.12695040
90Insulin resistance_Homo sapiens_hsa049310.12081744
91Glycerophospholipid metabolism_Homo sapiens_hsa005640.11457959
92Basal transcription factors_Homo sapiens_hsa030220.09736192
93Adipocytokine signaling pathway_Homo sapiens_hsa049200.08677582
94Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.05641398
95Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.04259882
96Arachidonic acid metabolism_Homo sapiens_hsa005900.02650229
97Glucagon signaling pathway_Homo sapiens_hsa049220.01637947
98Ovarian steroidogenesis_Homo sapiens_hsa049130.00529367
99Mineral absorption_Homo sapiens_hsa04978-0.2104043
100Systemic lupus erythematosus_Homo sapiens_hsa05322-0.2088929
101Bladder cancer_Homo sapiens_hsa05219-0.2065501
102Carbohydrate digestion and absorption_Homo sapiens_hsa04973-0.2026294
103Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970-0.1991668
104Insulin signaling pathway_Homo sapiens_hsa04910-0.1916777
105Ether lipid metabolism_Homo sapiens_hsa00565-0.1753843
106Oxidative phosphorylation_Homo sapiens_hsa00190-0.1665227
107Thyroid hormone synthesis_Homo sapiens_hsa04918-0.1593659
108Renin-angiotensin system_Homo sapiens_hsa04614-0.0797286
109Glycosaminoglycan degradation_Homo sapiens_hsa00531-0.0725936
110Protein digestion and absorption_Homo sapiens_hsa04974-0.0702188
111Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141-0.0681832
112AMPK signaling pathway_Homo sapiens_hsa04152-0.0390855
113Regulation of autophagy_Homo sapiens_hsa04140-0.0389209
114Protein export_Homo sapiens_hsa03060-0.0264158
115Other glycan degradation_Homo sapiens_hsa00511-0.0158145
116Pyrimidine metabolism_Homo sapiens_hsa00240-0.0113068

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