PELI1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1positive regulation of gamma-delta T cell activation (GO:0046645)5.13555792
2positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)5.00253291
3macrophage activation involved in immune response (GO:0002281)4.88602876
4detection of molecule of bacterial origin (GO:0032490)4.84785966
5negative regulation of interleukin-12 production (GO:0032695)4.83672503
6negative regulation of leukocyte mediated cytotoxicity (GO:0001911)4.80178082
7negative regulation of cell killing (GO:0031342)4.80178082
8T cell migration (GO:0072678)4.53364039
9positive regulation of interleukin-2 biosynthetic process (GO:0045086)4.49979483
10regulation of interferon-beta biosynthetic process (GO:0045357)4.43353698
11regulation of isotype switching to IgG isotypes (GO:0048302)4.41739594
12detection of other organism (GO:0098543)4.38506940
13activated T cell proliferation (GO:0050798)4.34974784
14negative T cell selection (GO:0043383)4.27721644
15leukocyte aggregation (GO:0070486)4.26133558
16cellular extravasation (GO:0045123)4.16946654
17negative thymic T cell selection (GO:0045060)4.12905752
18positive regulation of T cell cytokine production (GO:0002726)4.12110478
19microglial cell activation (GO:0001774)4.09384781
20regulation of interleukin-12 biosynthetic process (GO:0045075)4.09242948
21detection of external biotic stimulus (GO:0098581)4.06525400
22neutrophil activation involved in immune response (GO:0002283)3.99261158
23response to immune response of other organism involved in symbiotic interaction (GO:0052564)3.96930381
24response to host immune response (GO:0052572)3.96930381
25regulation of T cell tolerance induction (GO:0002664)3.93168628
26neutrophil mediated immunity (GO:0002446)3.89511061
27detection of bacterium (GO:0016045)3.86846529
28germinal center formation (GO:0002467)3.84463603
29macrophage activation (GO:0042116)3.81976634
30detection of biotic stimulus (GO:0009595)3.77078524
31regulation of alpha-beta T cell proliferation (GO:0046640)3.76692081
32interferon-gamma production (GO:0032609)3.74820589
33positive regulation by symbiont of host defense response (GO:0052509)3.74253246
34modulation by symbiont of host defense response (GO:0052031)3.74253246
35modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.74253246
36modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.74253246
37positive regulation by organism of defense response of other organism involved in symbiotic interact3.74253246
38modulation by symbiont of host immune response (GO:0052553)3.74253246
39regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)3.73061789
40antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.71545630
41positive regulation of interleukin-2 production (GO:0032743)3.70782492
42NIK/NF-kappaB signaling (GO:0038061)3.70391617
43positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.69513098
44regulation of gamma-delta T cell activation (GO:0046643)3.68973222
45positive regulation of interleukin-8 biosynthetic process (GO:0045416)3.65526291
46response to defenses of other organism involved in symbiotic interaction (GO:0052173)3.60166531
47response to host (GO:0075136)3.60166531
48response to host defenses (GO:0052200)3.60166531
49positive thymic T cell selection (GO:0045059)3.57428214
50type I interferon signaling pathway (GO:0060337)3.56641280
51cellular response to type I interferon (GO:0071357)3.56641280
52response to type I interferon (GO:0034340)3.56354163
53lipopolysaccharide-mediated signaling pathway (GO:0031663)3.55949446
54immunoglobulin mediated immune response (GO:0016064)3.52305013
55positive T cell selection (GO:0043368)3.51600953
56antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.50800365
57antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.50800365
58regulation of gamma-delta T cell differentiation (GO:0045586)3.50563307
59regulation of nitric-oxide synthase biosynthetic process (GO:0051769)3.49493430
60positive regulation of alpha-beta T cell proliferation (GO:0046641)3.47021901
61T-helper 1 type immune response (GO:0042088)3.46897330
62antigen processing and presentation of endogenous antigen (GO:0019883)3.44567872
63negative regulation of lymphocyte mediated immunity (GO:0002707)3.43606795
64tolerance induction (GO:0002507)3.43311719
65response to muramyl dipeptide (GO:0032495)3.41059587
66response to protozoan (GO:0001562)3.39087127
67regulation of chronic inflammatory response (GO:0002676)3.35242557
68T cell selection (GO:0045058)3.34978525
69positive regulation of humoral immune response (GO:0002922)3.33924769
70myeloid leukocyte mediated immunity (GO:0002444)3.33847639
71T-helper cell differentiation (GO:0042093)3.33695464
72CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294)3.33695464
73production of molecular mediator involved in inflammatory response (GO:0002532)3.33647226
74regulation of interleukin-8 biosynthetic process (GO:0045414)3.33500386
75myeloid cell activation involved in immune response (GO:0002275)3.32699301
76respiratory burst (GO:0045730)3.31839037
77regulation of interleukin-2 biosynthetic process (GO:0045076)3.30563553
78T cell receptor signaling pathway (GO:0050852)3.28063786
79positive regulation of isotype switching (GO:0045830)3.27479636
80cellular response to interleukin-15 (GO:0071350)3.27360715
81alpha-beta T cell activation (GO:0046631)3.25314789
82positive regulation of interleukin-17 production (GO:0032740)3.24434457
83T cell differentiation involved in immune response (GO:0002292)3.22753268
84alpha-beta T cell differentiation involved in immune response (GO:0002293)3.22753268
85alpha-beta T cell activation involved in immune response (GO:0002287)3.22753268
86regulation of tumor necrosis factor biosynthetic process (GO:0042534)3.22254080
87regulation of T-helper 2 cell differentiation (GO:0045628)3.21792943
88B cell receptor signaling pathway (GO:0050853)3.21359457
89alpha-beta T cell differentiation (GO:0046632)3.19888646
90regulation of T cell cytokine production (GO:0002724)3.19834201
91positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)3.18576759
92regulation of B cell receptor signaling pathway (GO:0050855)3.17822728
93T cell costimulation (GO:0031295)3.14632495
94thymic T cell selection (GO:0045061)3.14428211
95positive regulation of immunoglobulin mediated immune response (GO:0002891)3.12058333
96positive regulation of B cell mediated immunity (GO:0002714)3.12058333
97lymphocyte costimulation (GO:0031294)3.10289275
98negative regulation of T cell mediated immunity (GO:0002710)3.09510502
99regulation of tolerance induction (GO:0002643)3.09434687
100positive regulation of interferon-beta production (GO:0032728)3.04633658
101negative regulation of interleukin-6 production (GO:0032715)3.04559083
102regulation of immunoglobulin secretion (GO:0051023)3.02733756
103response to interleukin-15 (GO:0070672)3.01811996
104negative regulation of cytokine production involved in immune response (GO:0002719)3.01530029
105positive regulation of interleukin-12 production (GO:0032735)3.00447511
106negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)2.97660443
107negative regulation of toll-like receptor signaling pathway (GO:0034122)2.95483670
108positive regulation of DNA recombination (GO:0045911)2.95389148
109antigen receptor-mediated signaling pathway (GO:0050851)2.95078751
110regulation of dendritic cell antigen processing and presentation (GO:0002604)2.94321351
111negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)2.92160577
112negative regulation of T-helper cell differentiation (GO:0045623)2.92160577
113regulation of T cell receptor signaling pathway (GO:0050856)2.91844338
114regulation of antigen receptor-mediated signaling pathway (GO:0050854)2.91748876
115positive regulation of B cell differentiation (GO:0045579)2.91083428
116positive regulation of tolerance induction (GO:0002645)2.90537277
117negative regulation of leukocyte mediated immunity (GO:0002704)2.90050869
118regulation of T-helper 1 cell differentiation (GO:0045625)2.89571736
119regulation of isotype switching (GO:0045191)2.88657581
120interferon-gamma-mediated signaling pathway (GO:0060333)2.88247444
121positive regulation of NF-kappaB import into nucleus (GO:0042346)2.87750452
122T cell proliferation (GO:0042098)2.87120584
123regulation of vitamin D biosynthetic process (GO:0060556)2.87045412
124regulation of interferon-alpha production (GO:0032647)2.85837049
125CD4-positive, alpha-beta T cell differentiation (GO:0043367)2.85613901
126regulation of regulatory T cell differentiation (GO:0045589)2.85563113
127negative regulation of B cell proliferation (GO:0030889)2.84896629
128myeloid dendritic cell differentiation (GO:0043011)2.83323581
129positive regulation of cellular amide metabolic process (GO:0034250)2.83253258
130regulation of interleukin-12 production (GO:0032655)2.83093881
131B cell mediated immunity (GO:0019724)2.82608911
132leukocyte cell-cell adhesion (GO:0007159)2.82231266
133myeloid leukocyte activation (GO:0002274)2.82037899
134positive regulation of interferon-alpha production (GO:0032727)2.81697331
135positive regulation of type 2 immune response (GO:0002830)2.81287646
136regulation of B cell differentiation (GO:0045577)2.80181155
137regulation of immunoglobulin mediated immune response (GO:0002889)2.79990574
138response to peptidoglycan (GO:0032494)2.79075158
139regulation of interleukin-17 production (GO:0032660)2.78932330
140positive regulation of interleukin-1 beta secretion (GO:0050718)2.78175261
141regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043370)2.77337399
142* regulation of toll-like receptor signaling pathway (GO:0034121)2.76768665
143T cell activation involved in immune response (GO:0002286)2.75903696
144cellular response to interferon-beta (GO:0035458)2.73995018
145regulation of interleukin-2 production (GO:0032663)2.73415835
146natural killer cell activation (GO:0030101)2.72984445
147myeloid dendritic cell activation (GO:0001773)2.72244086
148positive regulation of chemokine biosynthetic process (GO:0045080)2.71851560
149positive regulation of interferon-gamma production (GO:0032729)2.71191175
150granulocyte activation (GO:0036230)2.70990892
151neutrophil activation (GO:0042119)2.70191295
152regulation of CD4-positive, alpha-beta T cell activation (GO:2000514)2.69988321
153regulation of B cell mediated immunity (GO:0002712)2.69690103
154defense response to protozoan (GO:0042832)2.68843811
155Arp2/3 complex-mediated actin nucleation (GO:0034314)2.68821683
156positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372)2.68765445

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1* FOXP3_17237761_ChIP-ChIP_TREG_Mouse8.00885130
2IRF8_22096565_ChIP-ChIP_GC-B_Human5.36696303
3STAT6_20620947_ChIP-Seq_CD4_POS_T_Human5.15907172
4IRF8_21731497_ChIP-ChIP_J774_Mouse4.49288465
5IRF8_22096565_ChIP-ChIP_GC-B_Mouse4.31621269
6IRF1_21803131_ChIP-Seq_MONOCYTES_Human4.25030552
7STAT3_20064451_ChIP-Seq_CD4+T_Mouse4.15999976
8RUNX_20019798_ChIP-Seq_JUKART_Human3.44746442
9BP1_19119308_ChIP-ChIP_Hs578T_Human3.34429427
10STAT4_19710469_ChIP-ChIP_TH1__Mouse3.10243331
11* IRF8_27001747_Chip-Seq_BMDM_Mouse2.98764448
12FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse2.93736362
13* SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.91559953
14EGR1_19374776_ChIP-ChIP_THP-1_Human2.71685491
15MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.65023225
16VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human2.59644448
17SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.58427725
18MYB_26560356_Chip-Seq_TH2_Human2.56727810
19* NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.51372957
20RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human2.35446977
21SMAD_19615063_ChIP-ChIP_OVARY_Human2.20559079
22NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.19760822
23MAF_26560356_Chip-Seq_TH1_Human2.11047569
24HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.04793427
25MYB_26560356_Chip-Seq_TH1_Human2.00536475
26STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.78013323
27VDR_24787735_ChIP-Seq_THP-1_Human1.77257847
28Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.73925273
29KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.69237732
30KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.69237732
31KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.69237732
32CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.65543205
33SCL_19346495_ChIP-Seq_HPC-7_Human1.64689521
34VDR_24763502_ChIP-Seq_THP-1_Human1.62383198
35TP63_19390658_ChIP-ChIP_HaCaT_Human1.62317265
36* GATA3_27048872_Chip-Seq_THYMUS_Human1.61751114
37UTX_26944678_Chip-Seq_JUKART_Human1.60069706
38MYB_21317192_ChIP-Seq_ERMYB_Mouse1.55847873
39CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.55266496
40NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.54284391
41SPI1_23547873_ChIP-Seq_NB4_Human1.50279691
42BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.47914235
43RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.46497691
44* PU_27001747_Chip-Seq_BMDM_Mouse1.36528925
45GATA1_22025678_ChIP-Seq_K562_Human1.34545611
46AR_21572438_ChIP-Seq_LNCaP_Human1.33005924
47PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.30982527
48ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.30117828
49* KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.29416000
50TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.27457224
51WT1_19549856_ChIP-ChIP_CCG9911_Human1.26869220
52RUNX1_22412390_ChIP-Seq_EML_Mouse1.21881015
53IGF1R_20145208_ChIP-Seq_DFB_Human1.21581321
54TCF7_22412390_ChIP-Seq_EML_Mouse1.19949555
55TAF15_26573619_Chip-Seq_HEK293_Human1.18675609
56VDR_21846776_ChIP-Seq_THP-1_Human1.17947256
57NOTCH1_21737748_ChIP-Seq_TLL_Human1.17471514
58MAF_26560356_Chip-Seq_TH2_Human1.14812841
59KDM2B_26808549_Chip-Seq_DND41_Human1.14344130
60SPI1_23127762_ChIP-Seq_K562_Human1.10771897
61CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.10256885
62NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.09753892
63MYC_22102868_ChIP-Seq_BL_Human1.09398298
64PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.05597523
65MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.04642544
66KDM2B_26808549_Chip-Seq_SUP-B15_Human1.04547485
67GATA1_19941827_ChIP-Seq_MEL_Mouse0.99465411
68PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.99397152
69BRD4_27068464_Chip-Seq_AML-cells_Mouse0.98947795
70STAT6_21828071_ChIP-Seq_BEAS2B_Human0.98672710
71* CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.96647808
72E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human0.96100399
73KDM2B_26808549_Chip-Seq_JURKAT_Human0.95435704
74GATA3_26560356_Chip-Seq_TH2_Human0.91822645
75LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.91491239
76* CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.88056313
77* CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.86264138
78POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.85136740
79TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.85136740
80VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.84631788
81KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.84532761
82RUNX1_20887958_ChIP-Seq_HPC-7_Mouse0.83229153
83SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.82687114
84GATA1_19941826_ChIP-Seq_K562_Human0.82623385
85STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.82504132
86* PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.82202246
87GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.82135435
88GATA1_19941827_ChIP-Seq_MEL86_Mouse0.82040290
89FOXO3_23340844_ChIP-Seq_DLD1_Human0.80102943
90ZFP57_27257070_Chip-Seq_ESCs_Mouse0.79419035
91* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.74576841
92GATA2_19941826_ChIP-Seq_K562_Human0.74332531
93* SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.73707626
94* SMRT_27268052_Chip-Seq_Bcells_Human0.73444713
95EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse0.71705172
96* CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse0.70220345
97GATA2_21666600_ChIP-Seq_HMVEC_Human0.68869088
98FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.68502329
99GATA2_22383799_ChIP-Seq_G1ME_Mouse0.67198369
100POU3F2_20337985_ChIP-ChIP_501MEL_Human0.67177073
101KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse0.66100840
102LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.65973439
103GATA1_22383799_ChIP-Seq_G1ME_Mouse0.65914074
104CMYC_18555785_Chip-Seq_ESCs_Mouse0.65548573
105FOXO1_23066095_ChIP-Seq_LIVER_Mouse0.65188613
106* PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.65059784
107IKZF1_21737484_ChIP-ChIP_HCT116_Human0.65057669
108EGR1_19032775_ChIP-ChIP_M12_Human0.65047796
109SALL4_18804426_ChIP-ChIP_XEN_Mouse0.64833418
110SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.64582692
111OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.64471100
112PHC1_16625203_ChIP-ChIP_MESCs_Mouse0.63961083
113PCGF2_27294783_Chip-Seq_NPCs_Mouse0.63892789
114TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.63218128
115* RXR_22108803_ChIP-Seq_LS180_Human0.61542837
116PRDM14_20953172_ChIP-Seq_ESCs_Human0.61482607
117RNF2_27304074_Chip-Seq_NSC_Mouse0.61338877
118* P300_19829295_ChIP-Seq_ESCs_Human0.61024020
119* ZNF217_24962896_ChIP-Seq_MCF-7_Human0.60427020
120FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human0.60335910
121RNF2_16625203_ChIP-ChIP_MESCs_Mouse0.59884851
122PKCTHETA_26484144_Chip-Seq_BREAST_Human0.59625116
123* CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.59382237
124ER_23166858_ChIP-Seq_MCF-7_Human0.59059469
125GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.58502367
126EZH2_27294783_Chip-Seq_NPCs_Mouse0.58140609
127FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.57169705
128SUZ12_18555785_Chip-Seq_ESCs_Mouse0.56967030

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005671_abnormal_response_to4.04006692
2MP0001835_abnormal_antigen_presentation3.83145725
3MP0009785_altered_susceptibility_to3.69636149
4MP0003763_abnormal_thymus_physiology3.60550359
5MP0005000_abnormal_immune_tolerance3.33401246
6MP0002148_abnormal_hypersensitivity_rea3.15383112
7MP0000685_abnormal_immune_system3.13624195
8MP0003436_decreased_susceptibility_to3.04301735
9MP0001800_abnormal_humoral_immune3.02179410
10MP0001790_abnormal_immune_system2.99254314
11MP0005387_immune_system_phenotype2.99254314
12MP0006082_CNS_inflammation2.89739480
13* MP0002723_abnormal_immune_serum2.80709949
14* MP0002452_abnormal_antigen_presenting2.75240576
15MP0003303_peritoneal_inflammation2.74925584
16MP0005025_abnormal_response_to2.70873876
17MP0003724_increased_susceptibility_to2.64895175
18* MP0001819_abnormal_immune_cell2.62393934
19* MP0002420_abnormal_adaptive_immunity2.61024409
20MP0004510_myositis2.37748603
21MP0002419_abnormal_innate_immunity2.37695493
22MP0002006_tumorigenesis2.20628716
23* MP0002398_abnormal_bone_marrow2.15762648
24MP0002405_respiratory_system_inflammati2.14877344
25MP0009333_abnormal_splenocyte_physiolog2.12355317
26MP0002166_altered_tumor_susceptibility2.06709814
27* MP0000716_abnormal_immune_system2.06022626
28MP0004947_skin_inflammation2.03953316
29MP0004381_abnormal_hair_follicle1.96006366
30MP0008004_abnormal_stomach_pH1.92056403
31MP0010155_abnormal_intestine_physiology1.88380710
32MP0000703_abnormal_thymus_morphology1.60019047
33MP0002009_preneoplasia1.58172197
34* MP0002429_abnormal_blood_cell1.57275206
35MP0001873_stomach_inflammation1.57138520
36MP0000689_abnormal_spleen_morphology1.55460263
37MP0002722_abnormal_immune_system1.54526847
38MP0001853_heart_inflammation1.54493787
39MP0005310_abnormal_salivary_gland1.53871909
40MP0003448_altered_tumor_morphology1.52539451
41* MP0001845_abnormal_inflammatory_respons1.48749152
42MP0009278_abnormal_bone_marrow1.45150991
43MP0001533_abnormal_skeleton_physiology1.43761371
44MP0005451_abnormal_body_composition1.38363798
45MP0002933_joint_inflammation1.36773420
46MP0003300_gastrointestinal_ulcer1.35411602
47MP0000569_abnormal_digit_pigmentation1.35142756
48MP0003075_altered_response_to1.34635036
49MP0004883_abnormal_blood_vessel1.31931424
50MP0002332_abnormal_exercise_endurance1.28005483
51MP0003221_abnormal_cardiomyocyte_apopto1.26927242
52MP0002254_reproductive_system_inflammat1.25945458
53MP0002277_abnormal_respiratory_mucosa1.23907673
54MP0003191_abnormal_cellular_cholesterol1.23649212
55MP0005164_abnormal_response_to1.22611022
56MP0002998_abnormal_bone_remodeling1.21968755
57MP0001851_eye_inflammation1.20832427
58MP0003866_abnormal_defecation1.18700912
59MP0003656_abnormal_erythrocyte_physiolo1.18529360
60MP0005464_abnormal_platelet_physiology1.17434830
61MP0004742_abnormal_vestibular_system1.15690211
62MP0000920_abnormal_myelination1.08535029
63MP0003172_abnormal_lysosome_physiology1.07052073
64MP0000778_abnormal_nervous_system1.06003416
65* MP0008469_abnormal_protein_level1.04831115
66MP0005167_abnormal_blood-brain_barrier1.02346343
67MP0000465_gastrointestinal_hemorrhage1.01548976
68* MP0009764_decreased_sensitivity_to0.98657410
69MP0008057_abnormal_DNA_replication0.94697142
70MP0005174_abnormal_tail_pigmentation0.93927116
71MP0001545_abnormal_hematopoietic_system0.91315722
72MP0005397_hematopoietic_system_phenotyp0.91315722
73MP0010352_gastrointestinal_tract_polyps0.89587147
74MP0003091_abnormal_cell_migration0.88237977
75MP0000858_altered_metastatic_potential0.87627119
76MP0004808_abnormal_hematopoietic_stem0.86315790
77MP0003453_abnormal_keratinocyte_physiol0.84044694
78MP0003136_yellow_coat_color0.82103664
79MP0000383_abnormal_hair_follicle0.81513415
80MP0005423_abnormal_somatic_nervous0.77348629
81MP0000249_abnormal_blood_vessel0.73896528
82MP0008995_early_reproductive_senescence0.73814932
83MP0000490_abnormal_crypts_of0.73466497
84MP0000343_altered_response_to0.72066715
85MP0008260_abnormal_autophagy0.71857699
86MP0003787_abnormal_imprinting0.71226211
87MP0002138_abnormal_hepatobiliary_system0.69003569
88MP0002653_abnormal_ependyma_morphology0.66839875
89MP0005390_skeleton_phenotype0.65452812
90MP0003045_fibrosis0.65281448
91MP0002102_abnormal_ear_morphology0.65209612
92MP0004484_altered_response_of0.64025875
93MP0003183_abnormal_peptide_metabolism0.63089053
94MP0003195_calcinosis0.60260401
95MP0005645_abnormal_hypothalamus_physiol0.60133891
96MP0005076_abnormal_cell_differentiation0.58898372
97MP0000015_abnormal_ear_pigmentation0.57512837
98MP0004134_abnormal_chest_morphology0.54540888
99MP0005166_decreased_susceptibility_to0.52877614
100MP0003795_abnormal_bone_structure0.52736395
101MP0000604_amyloidosis0.52469898
102MP0002396_abnormal_hematopoietic_system0.51863847
103MP0002133_abnormal_respiratory_system0.51573755
104MP0005388_respiratory_system_phenotype0.51573755
105MP0005075_abnormal_melanosome_morpholog0.51497054
106MP0005409_darkened_coat_color0.51173411
107MP0002132_abnormal_respiratory_system0.50299981
108MP0003828_pulmonary_edema0.50272815
109MP0003690_abnormal_glial_cell0.50083041
110MP0005535_abnormal_body_temperature0.50052355
111MP0001663_abnormal_digestive_system0.49948109
112MP0000733_abnormal_muscle_development0.49441773
113MP0006054_spinal_hemorrhage0.49059561
114MP0008874_decreased_physiological_sensi0.48692344
115* MP0009765_abnormal_xenobiotic_induced0.48592549
116MP0005376_homeostasis/metabolism_phenot0.48294420
117MP0009763_increased_sensitivity_to0.47588233
118MP0010678_abnormal_skin_adnexa0.47571511
119MP0005171_absent_coat_pigmentation0.47328180
120MP0003880_abnormal_central_pattern0.46334436
121MP0008961_abnormal_basal_metabolism0.45288136
122MP0003943_abnormal_hepatobiliary_system0.45059974
123MP0001216_abnormal_epidermal_layer0.44585647
124MP0002019_abnormal_tumor_incidence0.44516872

Predicted human phenotypes

RankGene SetZ-score
1Elevated erythrocyte sedimentation rate (HP:0003565)4.88511304
2Stomatitis (HP:0010280)4.78682656
3Eczematoid dermatitis (HP:0000976)4.63042585
4T lymphocytopenia (HP:0005403)4.37508725
5Abnormality of T cell number (HP:0011839)4.34165718
6Retrobulbar optic neuritis (HP:0100654)4.26842349
7Optic neuritis (HP:0100653)4.26842349
8Increased IgM level (HP:0003496)4.14468216
9Recurrent abscess formation (HP:0002722)4.08717422
10Mediastinal lymphadenopathy (HP:0100721)4.07914206
11Recurrent fungal infections (HP:0002841)4.04708616
12Myositis (HP:0100614)3.89392915
13Severe combined immunodeficiency (HP:0004430)3.87869063
14Recurrent viral infections (HP:0004429)3.82864503
15Orchitis (HP:0100796)3.69281218
16Recurrent cutaneous fungal infections (HP:0011370)3.61839427
17Chronic mucocutaneous candidiasis (HP:0002728)3.61839427
18Vasculitis (HP:0002633)3.59626437
19Recurrent bacterial skin infections (HP:0005406)3.55920566
20Combined immunodeficiency (HP:0005387)3.44511569
21Chronic otitis media (HP:0000389)3.43776791
22Pulmonary infiltrates (HP:0002113)3.30577171
23Thyroiditis (HP:0100646)3.22033533
24Recurrent bronchitis (HP:0002837)3.19405365
25Abnormality of T cells (HP:0002843)3.18422258
26Chronic obstructive pulmonary disease (HP:0006510)3.16499894
27Obstructive lung disease (HP:0006536)3.16499894
28Autoimmune hemolytic anemia (HP:0001890)3.16323176
29Abnormality of eosinophils (HP:0001879)3.12217791
30Autoimmune thrombocytopenia (HP:0001973)3.11326006
31Urticaria (HP:0001025)3.11010290
32Recurrent skin infections (HP:0001581)3.10612243
33Leukocytosis (HP:0001974)3.06316894
34Hypergammaglobulinemia (HP:0010702)2.99702520
35Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.96708643
36Eosinophilia (HP:0001880)2.96658488
37B lymphocytopenia (HP:0010976)2.94411038
38Abnormality of B cell number (HP:0010975)2.94411038
39IgG deficiency (HP:0004315)2.93616701
40Panhypogammaglobulinemia (HP:0003139)2.86815676
41Abnormality of macrophages (HP:0004311)2.81926011
42Chronic diarrhea (HP:0002028)2.77792343
43Porencephaly (HP:0002132)2.75367149
44Hemoptysis (HP:0002105)2.75220826
45Gingivitis (HP:0000230)2.73815907
46Meningitis (HP:0001287)2.67526407
47Agammaglobulinemia (HP:0004432)2.65159445
48Anorexia (HP:0002039)2.62742798
49Episodic fever (HP:0001954)2.61989630
50Neoplasm of the tracheobronchial system (HP:0100552)2.53711962
51Lymphopenia (HP:0001888)2.52003701
52Abnormality of the fingertips (HP:0001211)2.49620022
53Gastrointestinal infarctions (HP:0005244)2.49348885
54Recurrent gram-negative bacterial infections (HP:0005420)2.48905366
55Peritonitis (HP:0002586)2.47071768
56Abnormality of cells of the lymphoid lineage (HP:0012140)2.44374870
57Sepsis (HP:0100806)2.42386351
58Keratoconjunctivitis sicca (HP:0001097)2.40973824
59Hematochezia (HP:0002573)2.40374463
60IgM deficiency (HP:0002850)2.39027142
61Thick nail (HP:0001805)2.39008736
62Gingival bleeding (HP:0000225)2.37991148
63Granulocytopenia (HP:0001913)2.36588429
64Alveolar cell carcinoma (HP:0006519)2.36416993
65Abnormal delayed hypersensitivity skin test (HP:0002963)2.36340110
66Nasal polyposis (HP:0100582)2.28195767
67Slow saccadic eye movements (HP:0000514)2.26361417
68Osteomyelitis (HP:0002754)2.26280909
69Pustule (HP:0200039)2.23565357
70Abnormality of the peritoneum (HP:0002585)2.23175614
71Increased IgE level (HP:0003212)2.22560071
72Viral hepatitis (HP:0006562)2.21601378
73IgA deficiency (HP:0002720)2.21381610
74Amyloidosis (HP:0011034)2.21011557
75Keratitis (HP:0000491)2.20562898
76Inflammation of the large intestine (HP:0002037)2.19971124
77Keratoconjunctivitis (HP:0001096)2.19128617
78Basal ganglia calcification (HP:0002135)2.18797744
79Parakeratosis (HP:0001036)2.18046038
80Subacute progressive viral hepatitis (HP:0006572)2.17966230
81Arterial thrombosis (HP:0004420)2.15169298
82Joint swelling (HP:0001386)2.13510503
83Vertigo (HP:0002321)2.13139356
84Abnormality of the endocardium (HP:0004306)2.11616463
85Polyneuropathy (HP:0001271)2.09319032
86Recurrent sinusitis (HP:0011108)2.08357880
87Trigonocephaly (HP:0000243)2.07801229
88Abnormality of T cell physiology (HP:0011840)2.07033310
89Gastrointestinal inflammation (HP:0004386)2.04187594
90Glomerulopathy (HP:0100820)2.04037525
91Amaurosis fugax (HP:0100576)2.02681827
92Prolonged bleeding time (HP:0003010)2.01206166
93Encephalitis (HP:0002383)2.00241156
94Epistaxis (HP:0000421)1.98791642
95Gangrene (HP:0100758)1.98179614
96Segmental peripheral demyelination/remyelination (HP:0003481)1.97239267
97Premature loss of primary teeth (HP:0006323)1.96265013
98Thrombophlebitis (HP:0004418)1.95849478
99Chest pain (HP:0100749)1.93049360
100Colitis (HP:0002583)1.91458038
101Chronic sinusitis (HP:0011109)1.90336155
102Plagiocephaly (HP:0001357)1.90191451
103Gastrointestinal stroma tumor (HP:0100723)1.89562544
104Abnormality of the nasal mucosa (HP:0000433)1.89114356
105Spontaneous hematomas (HP:0007420)1.88030509
106Abnormality of the prostate (HP:0008775)1.86841597
107Interstitial pulmonary disease (HP:0006530)1.85825025
108Abnormality of the pleura (HP:0002103)1.85815871
109Recurrent pneumonia (HP:0006532)1.85219085
110Periodontitis (HP:0000704)1.83166695
111Bronchitis (HP:0012387)1.81350095
112Large earlobe (HP:0009748)1.81270655
113Verrucae (HP:0200043)1.81154302
114Papilloma (HP:0012740)1.81154302
115Abnormality of the nasal septum (HP:0000419)1.80361979
116Cheilitis (HP:0100825)1.80188508
117Loss of speech (HP:0002371)1.79634703
118Arthralgia (HP:0002829)1.73887985
119Cleft eyelid (HP:0000625)1.72824800
120Abnormality of the pericardium (HP:0001697)1.71920443
121Cellulitis (HP:0100658)1.71358150
122Adactyly (HP:0009776)1.70953614
123Lymphoma (HP:0002665)1.70365014
124Depressed nasal tip (HP:0000437)1.69688668
125Pulmonary embolism (HP:0002204)1.65577666
126Midline defect of the nose (HP:0004122)1.65471095
127Absent hand (HP:0004050)1.64356955
128Stomach cancer (HP:0012126)1.63049065
129Disinhibition (HP:0000734)1.62520751

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TXK4.98551722
2MAP3K143.63476202
3MAP4K13.37791068
4SIK32.90800456
5JAK32.74860317
6TYK22.54697646
7EPHA32.35402363
8* IKBKE2.30975359
9BLK2.25345194
10MAP2K32.19519587
11IKBKB2.11562639
12ITK2.04953477
13FGFR42.04237959
14ZAP702.00796730
15MAP3K131.96743174
16NLK1.96684496
17TAOK31.91257953
18* TBK11.91065777
19JAK11.90756080
20MST41.90134411
21TYRO31.85800102
22MATK1.83157047
23CHUK1.80388493
24EPHB11.70331262
25CSK1.68964507
26FGFR31.61532423
27TAOK11.53790818
28STK101.52513607
29PBK1.52170219
30LCK1.49539272
31IRAK31.46448169
32MAP3K31.44881968
33FES1.35941749
34MAP3K11.29317740
35PKN11.24804486
36TNIK1.23368060
37HCK1.22605157
38SIK21.22148075
39MARK31.21483612
40SYK1.21364599
41BMPR21.20856447
42NUAK11.20431910
43CLK11.18978980
44BCR1.16585669
45RIPK41.15115825
46BRD41.13100121
47BTK1.12410525
48TGFBR21.11835347
49ERN11.10813583
50PRKCQ1.10456087
51FGFR21.09787015
52KSR21.09679151
53GRK71.09605370
54STK241.07866855
55TNK21.07075316
56MAP3K111.03592206
57TAOK20.97629185
58KIT0.97062953
59LYN0.92795259
60MAP3K100.92415793
61SGK20.90855135
62TEC0.90551414
63PDGFRB0.88839169
64DYRK20.87034867
65FGR0.86867974
66RPS6KA40.86184034
67PIM10.81477274
68JAK20.80085257
69MAPK70.79981127
70MAP3K20.78006459
71MAP3K60.76631937
72KSR10.73433957
73SGK30.71891734
74MAPK130.71817546
75GRK60.71496385
76MOS0.70079175
77CDK190.70021277
78EIF2AK20.66245431
79CDC42BPA0.66101254
80BMPR1B0.64404760
81RIPK10.63528006
82TESK20.62932029
83TLK10.62005727
84WNK10.60397923
85YES10.60325665
86* IRAK10.58622063
87ERBB30.58300592
88CASK0.58011822
89MAPK150.57961313
90PDK10.55381917
91CDK60.54797689
92ACVR1B0.54557664
93RPS6KA50.54156977
94FYN0.54102833
95DYRK30.52999383
96CSF1R0.51367442
97STK40.50618110
98MELK0.50516692
99MARK10.48963789
100UHMK10.48322260
101STK110.47714501
102NTRK20.47707892
103ABL10.47655004
104LRRK20.46346479
105INSRR0.46281647
106PIK3CG0.46157753
107INSR0.46124565
108ERBB20.44702082
109MARK20.44628221
110MAP3K50.44454752
111HIPK20.43102827
112RAF10.42840379
113KDR0.42578177
114SGK2230.41635478
115SGK4940.41635478
116PRKD20.39053926
117PASK0.38122448
118DYRK1B0.37395453
119ICK0.35948432
120CSNK1A1L0.35269456
121PTK60.35237651
122MAP2K40.34771217
123EGFR0.34025000
124* IRAK40.33866953
125MAP3K70.33222995
126CDK40.33125387
127CAMK40.31248216
128PRKCD0.30375200
129PRPF4B0.29193920
130IGF1R0.28105442
131MAPKAPK20.27450470
132SRPK10.24716334
133PIM20.24164205
134FGFR10.23900942
135STK390.23065789
136DMPK0.21286982
137CDK120.21137569
138CSNK1G30.20443999

Predicted pathways (KEGG)

RankGene SetZ-score
1Graft-versus-host disease_Homo sapiens_hsa053323.25598859
2Allograft rejection_Homo sapiens_hsa053302.98646891
3Primary immunodeficiency_Homo sapiens_hsa053402.74791809
4NF-kappa B signaling pathway_Homo sapiens_hsa040642.56608682
5T cell receptor signaling pathway_Homo sapiens_hsa046602.43469981
6Inflammatory bowel disease (IBD)_Homo sapiens_hsa053212.36888863
7Leishmaniasis_Homo sapiens_hsa051402.36865920
8Measles_Homo sapiens_hsa051622.32927777
9Intestinal immune network for IgA production_Homo sapiens_hsa046722.16601225
10Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.11498352
11Osteoclast differentiation_Homo sapiens_hsa043802.08577745
12Toll-like receptor signaling pathway_Homo sapiens_hsa046202.03998320
13RIG-I-like receptor signaling pathway_Homo sapiens_hsa046222.01878950
14Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.97292392
15NOD-like receptor signaling pathway_Homo sapiens_hsa046211.90251265
16Autoimmune thyroid disease_Homo sapiens_hsa053201.88026513
17TNF signaling pathway_Homo sapiens_hsa046681.73717630
18Asthma_Homo sapiens_hsa053101.73102499
19Herpes simplex infection_Homo sapiens_hsa051681.62449087
20Viral myocarditis_Homo sapiens_hsa054161.60742198
21B cell receptor signaling pathway_Homo sapiens_hsa046621.60737987
22Type I diabetes mellitus_Homo sapiens_hsa049401.52216887
23Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.51422929
24Jak-STAT signaling pathway_Homo sapiens_hsa046301.50881545
25Influenza A_Homo sapiens_hsa051641.49972387
26Antigen processing and presentation_Homo sapiens_hsa046121.44773810
27Hematopoietic cell lineage_Homo sapiens_hsa046401.43960317
28Chemokine signaling pathway_Homo sapiens_hsa040621.41367037
29Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.41140634
30Malaria_Homo sapiens_hsa051441.39714433
31Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.39708357
32Toxoplasmosis_Homo sapiens_hsa051451.39091077
33Shigellosis_Homo sapiens_hsa051311.36114802
34Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.35065857
35Pertussis_Homo sapiens_hsa051331.32005691
36Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.31765880
37Rheumatoid arthritis_Homo sapiens_hsa053231.27823418
38Tuberculosis_Homo sapiens_hsa051521.24527048
39Salmonella infection_Homo sapiens_hsa051321.23154178
40Legionellosis_Homo sapiens_hsa051341.20617968
41Hepatitis B_Homo sapiens_hsa051611.15604379
42Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.14489136
43Hepatitis C_Homo sapiens_hsa051601.14203071
44Apoptosis_Homo sapiens_hsa042101.13440699
45African trypanosomiasis_Homo sapiens_hsa051431.05864909
46Staphylococcus aureus infection_Homo sapiens_hsa051501.03587002
47Chronic myeloid leukemia_Homo sapiens_hsa052200.99961897
48Leukocyte transendothelial migration_Homo sapiens_hsa046700.99185372
49Acute myeloid leukemia_Homo sapiens_hsa052210.97336712
50Notch signaling pathway_Homo sapiens_hsa043300.96482797
51Axon guidance_Homo sapiens_hsa043600.93778180
52Epstein-Barr virus infection_Homo sapiens_hsa051690.93729888
53AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.91358081
54Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.91175348
55Pancreatic cancer_Homo sapiens_hsa052120.86362338
56Colorectal cancer_Homo sapiens_hsa052100.85796144
57Transcriptional misregulation in cancer_Homo sapiens_hsa052020.80988760
58Prolactin signaling pathway_Homo sapiens_hsa049170.80292022
59Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.80173093
60Sphingolipid signaling pathway_Homo sapiens_hsa040710.79727488
61MicroRNAs in cancer_Homo sapiens_hsa052060.76721959
62Neurotrophin signaling pathway_Homo sapiens_hsa047220.76339183
63Renal cell carcinoma_Homo sapiens_hsa052110.72852591
64HTLV-I infection_Homo sapiens_hsa051660.71324465
65Platelet activation_Homo sapiens_hsa046110.71056738
66Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.68257970
67VEGF signaling pathway_Homo sapiens_hsa043700.62995674
68HIF-1 signaling pathway_Homo sapiens_hsa040660.62469745
69Prostate cancer_Homo sapiens_hsa052150.59612828
70Viral carcinogenesis_Homo sapiens_hsa052030.59309141
71Phagosome_Homo sapiens_hsa041450.58352836
72MAPK signaling pathway_Homo sapiens_hsa040100.57847325
73Choline metabolism in cancer_Homo sapiens_hsa052310.54118897
74Regulation of actin cytoskeleton_Homo sapiens_hsa048100.53301551
75Small cell lung cancer_Homo sapiens_hsa052220.52409873
76Other glycan degradation_Homo sapiens_hsa005110.52341352
77Adherens junction_Homo sapiens_hsa045200.49705375
78GnRH signaling pathway_Homo sapiens_hsa049120.48097370
79mTOR signaling pathway_Homo sapiens_hsa041500.47450092
80Dorso-ventral axis formation_Homo sapiens_hsa043200.47171504
81Carbohydrate digestion and absorption_Homo sapiens_hsa049730.47152791
82Inositol phosphate metabolism_Homo sapiens_hsa005620.46689097
83Insulin resistance_Homo sapiens_hsa049310.46143939
84Endocytosis_Homo sapiens_hsa041440.46101199
85Endometrial cancer_Homo sapiens_hsa052130.45242244
86Phospholipase D signaling pathway_Homo sapiens_hsa040720.44758913
87ErbB signaling pathway_Homo sapiens_hsa040120.43836438
88FoxO signaling pathway_Homo sapiens_hsa040680.43570573
89Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.43363080
90Prion diseases_Homo sapiens_hsa050200.40566678
91Ether lipid metabolism_Homo sapiens_hsa005650.39782457
92Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.39668364
93Proteoglycans in cancer_Homo sapiens_hsa052050.38922734
94Pathways in cancer_Homo sapiens_hsa052000.38761545
95Ras signaling pathway_Homo sapiens_hsa040140.38572954
96Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.37181793
97Adipocytokine signaling pathway_Homo sapiens_hsa049200.33926228
98Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.33692195
99Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.33574297
100Lysosome_Homo sapiens_hsa041420.33531205
101Amoebiasis_Homo sapiens_hsa051460.32421007
102Rap1 signaling pathway_Homo sapiens_hsa040150.32272011
103Non-small cell lung cancer_Homo sapiens_hsa052230.31300928
104Bladder cancer_Homo sapiens_hsa052190.30802115
105Longevity regulating pathway - mammal_Homo sapiens_hsa042110.30700339
106Phosphatidylinositol signaling system_Homo sapiens_hsa040700.30550621
107Estrogen signaling pathway_Homo sapiens_hsa049150.29625870
108Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.28439419
109TGF-beta signaling pathway_Homo sapiens_hsa043500.27945168
110Basal cell carcinoma_Homo sapiens_hsa052170.27658692
111Type II diabetes mellitus_Homo sapiens_hsa049300.27428149
112SNARE interactions in vesicular transport_Homo sapiens_hsa041300.27159758
113Steroid biosynthesis_Homo sapiens_hsa001000.25333178
114Systemic lupus erythematosus_Homo sapiens_hsa053220.25021478
115p53 signaling pathway_Homo sapiens_hsa041150.24055389

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