PELI3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene is a scaffold protein and an intermediate signaling protein in the innate immune response pathway. The encoded protein helps transmit the immune response signal from Toll-like receptors to IRAK1/TRAF6 complexes. Several transcript variants encoding different isoforms have been found for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of short-term neuronal synaptic plasticity (GO:0048172)5.94973132
2synaptic vesicle maturation (GO:0016188)5.71674388
3positive regulation of calcium ion-dependent exocytosis (GO:0045956)5.49883590
4regulation of synaptic vesicle exocytosis (GO:2000300)4.81505015
5positive regulation of synapse maturation (GO:0090129)4.73375351
6synaptic vesicle exocytosis (GO:0016079)4.71418488
7glutamate secretion (GO:0014047)4.63039643
8positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.61375016
9locomotory exploration behavior (GO:0035641)4.58605823
10regulation of ARF protein signal transduction (GO:0032012)4.44526648
11synaptic vesicle docking involved in exocytosis (GO:0016081)4.40798180
12cerebellar granule cell differentiation (GO:0021707)4.29561872
13regulation of synaptic vesicle transport (GO:1902803)4.28415864
14vocalization behavior (GO:0071625)4.26531455
15protein localization to synapse (GO:0035418)4.16883564
16regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.04831522
17neurotransmitter secretion (GO:0007269)4.04611717
18positive regulation of synaptic transmission, dopaminergic (GO:0032226)4.01182140
19regulation of glutamate receptor signaling pathway (GO:1900449)3.89684410
20regulation of rhodopsin mediated signaling pathway (GO:0022400)3.87400932
21L-amino acid import (GO:0043092)3.86145216
22layer formation in cerebral cortex (GO:0021819)3.83483591
23regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.80415974
24rhodopsin mediated signaling pathway (GO:0016056)3.75743207
25amino acid import (GO:0043090)3.72514261
26cellular potassium ion homeostasis (GO:0030007)3.72429254
27neuronal action potential propagation (GO:0019227)3.68033027
28cytoskeletal anchoring at plasma membrane (GO:0007016)3.67982639
29dendritic spine morphogenesis (GO:0060997)3.66740885
30regulation of neuronal synaptic plasticity (GO:0048168)3.63937276
31sodium ion export (GO:0071436)3.60363909
32neuromuscular process controlling posture (GO:0050884)3.59502873
33exploration behavior (GO:0035640)3.55234799
34ionotropic glutamate receptor signaling pathway (GO:0035235)3.51941520
35regulation of synapse maturation (GO:0090128)3.51098881
36membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.48748593
37neurotransmitter transport (GO:0006836)3.48062587
38neuron cell-cell adhesion (GO:0007158)3.43719412
39proline transport (GO:0015824)3.43362770
40synaptic transmission, glutamatergic (GO:0035249)3.42689142
41regulation of long-term neuronal synaptic plasticity (GO:0048169)3.42311842
42positive regulation of neurotransmitter secretion (GO:0001956)3.41527579
43G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)3.40581626
44regulation of synapse structural plasticity (GO:0051823)3.39468251
45neuron-neuron synaptic transmission (GO:0007270)3.38778710
46mating behavior (GO:0007617)3.35026427
47neuronal ion channel clustering (GO:0045161)3.31811780
48activation of protein kinase A activity (GO:0034199)3.31275101
49cerebellar Purkinje cell differentiation (GO:0021702)3.27690842
50regulation of clathrin-mediated endocytosis (GO:2000369)3.26504307
51synaptic vesicle endocytosis (GO:0048488)3.26111674
52positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.25863696
53positive regulation of dendritic spine development (GO:0060999)3.22519269
54regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.21758828
55neuron recognition (GO:0008038)3.21616799
56cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.17358550
57long-term memory (GO:0007616)3.16466404
58glutamate receptor signaling pathway (GO:0007215)3.14337857
59negative regulation of dendrite morphogenesis (GO:0050774)3.14229211
60vesicle transport along microtubule (GO:0047496)3.14129951
61regulation of neurotransmitter secretion (GO:0046928)3.13361166
62positive regulation of membrane potential (GO:0045838)3.13194578
63membrane depolarization during action potential (GO:0086010)3.12363815
64photoreceptor cell maintenance (GO:0045494)3.11137572
65photoreceptor cell development (GO:0042461)3.10901910
66gamma-aminobutyric acid transport (GO:0015812)3.10317276
67regulation of excitatory postsynaptic membrane potential (GO:0060079)3.09741791
68potassium ion import (GO:0010107)3.09721249
69neuromuscular process controlling balance (GO:0050885)3.09408115
70retinal rod cell development (GO:0046548)3.09220483
71glycine transport (GO:0015816)3.07809016
72regulation of postsynaptic membrane potential (GO:0060078)3.06982167
73negative regulation of amyloid precursor protein catabolic process (GO:1902992)3.06471602
74cell communication by electrical coupling (GO:0010644)3.04137034
75positive regulation of synaptic transmission, GABAergic (GO:0032230)3.03666762
76organelle transport along microtubule (GO:0072384)3.03653714
77membrane hyperpolarization (GO:0060081)3.02364750
78regulation of vesicle fusion (GO:0031338)3.02055449
79regulation of neurotransmitter levels (GO:0001505)3.02019573
80dendrite morphogenesis (GO:0048813)3.01519076
81cerebellar Purkinje cell layer development (GO:0021680)3.00825790
82neurotransmitter-gated ion channel clustering (GO:0072578)2.99583211
83axonal fasciculation (GO:0007413)2.98576455
84axon cargo transport (GO:0008088)2.98454671
85innervation (GO:0060384)2.98122974
86transmission of nerve impulse (GO:0019226)2.93383746
87positive regulation of protein dephosphorylation (GO:0035307)2.92395736
88eye photoreceptor cell development (GO:0042462)2.91338978
89negative regulation of synaptic transmission, GABAergic (GO:0032229)2.90253871
90potassium ion homeostasis (GO:0055075)2.90076909
91positive regulation of neurotransmitter transport (GO:0051590)2.89953229
92response to pheromone (GO:0019236)2.89867827
93positive regulation of potassium ion transmembrane transport (GO:1901381)2.89772454
94dendritic spine organization (GO:0097061)2.88883664
95regulation of neurotransmitter transport (GO:0051588)2.88865595
96chemosensory behavior (GO:0007635)2.88836598
97cell migration in hindbrain (GO:0021535)2.87923277
98central nervous system myelination (GO:0022010)2.87904232
99axon ensheathment in central nervous system (GO:0032291)2.87904232
100retinal cone cell development (GO:0046549)2.85732523
101regulation of exocytosis (GO:0017157)2.84857421
102synapse assembly (GO:0007416)2.83695519
103establishment of synaptic vesicle localization (GO:0097480)2.80928552
104synaptic vesicle transport (GO:0048489)2.80928552
105neuromuscular process (GO:0050905)2.80679797
106regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)2.79840163
107vesicle docking involved in exocytosis (GO:0006904)2.79810018
108suckling behavior (GO:0001967)2.79171666
109regulation of synaptic plasticity (GO:0048167)2.78370291
110positive regulation of synaptic transmission, glutamatergic (GO:0051968)2.77660386
111dicarboxylic acid transport (GO:0006835)2.77542111
112dopamine receptor signaling pathway (GO:0007212)2.77443920
113membrane depolarization (GO:0051899)2.77387792
114regulation of synaptic transmission (GO:0050804)2.77276173
115postsynaptic membrane organization (GO:0001941)2.76365291
116regulation of dendritic spine morphogenesis (GO:0061001)2.75855624
117adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)2.75744175
118urinary tract smooth muscle contraction (GO:0014848)2.74333191
119adult walking behavior (GO:0007628)2.73027328
120negative regulation of cytosolic calcium ion concentration (GO:0051481)2.72716255
121regulation of voltage-gated calcium channel activity (GO:1901385)2.72171379
122neuromuscular synaptic transmission (GO:0007274)2.71814160
123response to auditory stimulus (GO:0010996)2.71276747
124signal release (GO:0023061)2.70970501
125regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.70840110
126regulation of synaptic transmission, glutamatergic (GO:0051966)2.70304459
127mitochondrion transport along microtubule (GO:0047497)2.69680296
128establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.69680296
129protein localization to endosome (GO:0036010)2.65533891
130long-term synaptic potentiation (GO:0060291)2.65475852
131detection of calcium ion (GO:0005513)2.63697974
132receptor recycling (GO:0001881)2.62855842
133adenosine receptor signaling pathway (GO:0001973)2.62631476
134synaptic transmission (GO:0007268)2.61795222
135myelin maintenance (GO:0043217)2.60192819
136peptidyl-tyrosine autophosphorylation (GO:0038083)2.59161637
137gamma-aminobutyric acid signaling pathway (GO:0007214)2.57253700
138intraspecies interaction between organisms (GO:0051703)2.55988318
139social behavior (GO:0035176)2.55988318

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.06318223
2THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse3.43346111
3SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.91659883
4SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.88969808
5GBX2_23144817_ChIP-Seq_PC3_Human2.81789765
6* LXR_22292898_ChIP-Seq_THP-1_Human2.81596584
7JARID2_20064375_ChIP-Seq_MESCs_Mouse2.78837552
8EZH2_18974828_ChIP-Seq_MESCs_Mouse2.66646121
9RNF2_18974828_ChIP-Seq_MESCs_Mouse2.66646121
10REST_21632747_ChIP-Seq_MESCs_Mouse2.62878913
11JARID2_20075857_ChIP-Seq_MESCs_Mouse2.61368355
12SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.55670845
13DROSHA_22980978_ChIP-Seq_HELA_Human2.52032974
14MTF2_20144788_ChIP-Seq_MESCs_Mouse2.47977367
15RARB_27405468_Chip-Seq_BRAIN_Mouse2.47435070
16SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.42749724
17EZH2_27304074_Chip-Seq_ESCs_Mouse2.41090399
18SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.39149807
19SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.32887711
20EZH2_27294783_Chip-Seq_ESCs_Mouse2.32101137
21SUZ12_27294783_Chip-Seq_ESCs_Mouse2.31654359
22KDM2B_26808549_Chip-Seq_SUP-B15_Human2.29901644
23CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.28348805
24REST_18959480_ChIP-ChIP_MESCs_Mouse2.28296198
25ESR2_21235772_ChIP-Seq_MCF-7_Human2.25605083
26IKZF1_21737484_ChIP-ChIP_HCT116_Human2.24045326
27RNF2_27304074_Chip-Seq_ESCs_Mouse2.17600817
28EED_16625203_ChIP-ChIP_MESCs_Mouse2.12739755
29EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.10842109
30NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.05184834
31ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.94248799
32RARG_19884340_ChIP-ChIP_MEFs_Mouse1.93888341
33* SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.92062169
34TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.90077109
35ERG_21242973_ChIP-ChIP_JURKAT_Human1.89533233
36KDM2B_26808549_Chip-Seq_DND41_Human1.89305511
37MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.86158109
38* RACK7_27058665_Chip-Seq_MCF-7_Human1.84505647
39* P68_20966046_ChIP-Seq_HELA_Human1.76391437
40KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.70913065
41VDR_21846776_ChIP-Seq_THP-1_Human1.69600213
42* TET1_21451524_ChIP-Seq_MESCs_Mouse1.60427059
43SRY_22984422_ChIP-ChIP_TESTIS_Rat1.55551131
44CREB1_26743006_Chip-Seq_LNCaP_Human1.55116248
45GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.53243306
46SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.51705188
47AR_21572438_ChIP-Seq_LNCaP_Human1.50718297
48CTCF_27219007_Chip-Seq_ERYTHROID_Human1.49029288
49CTBP2_25329375_ChIP-Seq_LNCAP_Human1.45081611
50* UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.44606600
51ZFP281_18757296_ChIP-ChIP_E14_Mouse1.43410339
52SMAD4_21799915_ChIP-Seq_A2780_Human1.42515382
53ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.42067029
54PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.41203881
55SA1_27219007_Chip-Seq_ERYTHROID_Human1.40264857
56KDM2B_26808549_Chip-Seq_K562_Human1.40151019
57ELK3_25401928_ChIP-Seq_HUVEC_Human1.38824021
58TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.38690890
59* KDM2B_26808549_Chip-Seq_JURKAT_Human1.38387071
60RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.36723525
61RING1B_27294783_Chip-Seq_ESCs_Mouse1.35906468
62CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.35522213
63SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.33391242
64TCF7_22412390_ChIP-Seq_EML_Mouse1.32448398
65CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse1.31210906
66AR_19668381_ChIP-Seq_PC3_Human1.30586855
67* SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.30507952
68NR3C1_23031785_ChIP-Seq_PC12_Mouse1.30266834
69TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.30137248
70DNAJC2_21179169_ChIP-ChIP_NT2_Human1.29043990
71CTBP1_25329375_ChIP-Seq_LNCAP_Human1.28133037
72RING1B_27294783_Chip-Seq_NPCs_Mouse1.27373402
73* MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human1.26880989
74WT1_25993318_ChIP-Seq_PODOCYTE_Human1.25085891
75EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.24712417
76PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.23340923
77ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.18122756
78SOX2_21211035_ChIP-Seq_LN229_Gbm1.17834023
79SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.17660364
80BMI1_23680149_ChIP-Seq_NPCS_Mouse1.17584949
81RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.15288575
82PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.13540487
83WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.12592690
84OCT4_19829295_ChIP-Seq_ESCs_Human1.12407004
85CDX2_19796622_ChIP-Seq_MESCs_Mouse1.12358986
86* CTCF_27219007_Chip-Seq_Bcells_Human1.11465026
87ELF1_20517297_ChIP-Seq_JURKAT_Human1.10552398
88ZNF274_21170338_ChIP-Seq_K562_Hela1.10224672
89BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.09610764
90GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.09455984
91SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.08013224
92OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.07121072
93CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.06779635
94STAT3_23295773_ChIP-Seq_U87_Human1.05570854
95ZNF263_19887448_ChIP-Seq_K562_Human1.05047326
96TP53_22127205_ChIP-Seq_IMR90_Human1.03977807
97STAT3_19079543_ChIP-ChIP_MESCs_Mouse1.03828506
98CBX2_27304074_Chip-Seq_ESCs_Mouse1.02803825
99TOP2B_26459242_ChIP-Seq_MCF-7_Human1.02614169
100P300_27058665_Chip-Seq_ZR-75-30cells_Human1.02476275
101TFAP2A_17053090_ChIP-ChIP_MCF-7_Human1.02191274
102JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse1.02146529
103AR_25329375_ChIP-Seq_VCAP_Human1.01925779
104ZNF217_24962896_ChIP-Seq_MCF-7_Human1.01720349
105SA1_27219007_Chip-Seq_Bcells_Human1.01308063
106GATA3_20176728_ChIP-ChIP_TSCs_Mouse1.01121492
107SMAD4_21741376_ChIP-Seq_HESCs_Human1.00995353
108SETDB1_19884255_ChIP-Seq_MESCs_Mouse1.00992783
109TET1_21490601_ChIP-Seq_MESCs_Mouse1.00810529
110SMAD3_21741376_ChIP-Seq_EPCs_Human1.00513074
111TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.00420523
112GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.00219643
113P300_19829295_ChIP-Seq_ESCs_Human1.00043952
114RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.99735374
115TP63_22573176_ChIP-Seq_HFKS_Human0.99727478
116TP53_23651856_ChIP-Seq_MEFs_Mouse0.99395427
117NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.98472904
118BCOR_27268052_Chip-Seq_Bcells_Human0.98242535
119TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.97630389
120AHR_22903824_ChIP-Seq_MCF-7_Human0.97574011
121YAP1_20516196_ChIP-Seq_MESCs_Mouse0.97472559
122KDM2B_26808549_Chip-Seq_HPB-ALL_Human0.97375267
123* RUNX2_24764292_ChIP-Seq_MC3T3_Mouse0.96840339
124P53_22127205_ChIP-Seq_FIBROBLAST_Human0.94594674
125NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.94060663
126MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.93754040
127SMAD3_21741376_ChIP-Seq_HESCs_Human0.92776363
128PPARG_19300518_ChIP-PET_3T3-L1_Mouse0.92469897
129RARA_24833708_ChIP-Seq_LIVER_Mouse0.92445989
130PIAS1_25552417_ChIP-Seq_VCAP_Human0.92373132
131SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.92200108
132DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.92094871
133SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.91737724
134BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.91715393
135TAF15_26573619_Chip-Seq_HEK293_Human0.91318430
136SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.91059716
137SMAD3_21741376_ChIP-Seq_ESCs_Human0.90557684
138ARNT_22903824_ChIP-Seq_MCF-7_Human0.89123529
139OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.87879143
140ZFP281_27345836_Chip-Seq_ESCs_Mouse0.87597192
141RNF2_27304074_Chip-Seq_NSC_Mouse0.86809374
142DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.86065367
143TP53_20018659_ChIP-ChIP_R1E_Mouse0.85446073
144ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.85273494
145TCF4_23295773_ChIP-Seq_U87_Human0.84920388
146SMC4_20622854_ChIP-Seq_HELA_Human0.83212243
147VDR_22108803_ChIP-Seq_LS180_Human0.82280698
148ZFP57_27257070_Chip-Seq_ESCs_Mouse0.80181936
149PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.79578943
150KLF4_19829295_ChIP-Seq_ESCs_Human0.79510220
151STAT6_21828071_ChIP-Seq_BEAS2B_Human0.79257873

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity5.28241433
2MP0003880_abnormal_central_pattern4.14082523
3MP0003635_abnormal_synaptic_transmissio3.49161686
4MP0004270_analgesia3.46052982
5MP0005551_abnormal_eye_electrophysiolog3.39016291
6MP0001968_abnormal_touch/_nociception3.03938649
7MP0002063_abnormal_learning/memory/cond2.83678547
8MP0002064_seizures2.70766545
9MP0009745_abnormal_behavioral_response2.69643421
10MP0005423_abnormal_somatic_nervous2.65643831
11MP0009046_muscle_twitch2.63832775
12MP0006072_abnormal_retinal_apoptosis2.51384986
13MP0002734_abnormal_mechanical_nocicepti2.49331254
14MP0002822_catalepsy2.47195411
15MP0002272_abnormal_nervous_system2.37396713
16MP0002735_abnormal_chemical_nociception2.35834726
17MP0002572_abnormal_emotion/affect_behav2.35716662
18MP0001486_abnormal_startle_reflex2.27579430
19MP0005253_abnormal_eye_physiology2.25440720
20MP0000013_abnormal_adipose_tissue2.20472352
21MP0006276_abnormal_autonomic_nervous2.15473441
22MP0002733_abnormal_thermal_nociception2.08009684
23MP0003011_delayed_dark_adaptation2.02486329
24MP0002736_abnormal_nociception_after1.96546262
25MP0002067_abnormal_sensory_capabilities1.93357174
26MP0004858_abnormal_nervous_system1.92161047
27MP0001970_abnormal_pain_threshold1.91491652
28MP0003123_paternal_imprinting1.85927284
29MP0009780_abnormal_chondrocyte_physiolo1.82150125
30MP0003329_amyloid_beta_deposits1.81988854
31MP0001440_abnormal_grooming_behavior1.80418109
32MP0001501_abnormal_sleep_pattern1.80370203
33MP0001502_abnormal_circadian_rhythm1.79600650
34MP0002909_abnormal_adrenal_gland1.76670670
35MP0002184_abnormal_innervation1.76311981
36MP0003705_abnormal_hypodermis_morpholog1.75507115
37MP0002229_neurodegeneration1.74574469
38MP0002638_abnormal_pupillary_reflex1.73172414
39MP0005058_abnormal_lysosome_morphology1.71096978
40MP0002882_abnormal_neuron_morphology1.67173418
41MP0004811_abnormal_neuron_physiology1.66644012
42MP0000778_abnormal_nervous_system1.65806935
43MP0003122_maternal_imprinting1.54814622
44MP0000955_abnormal_spinal_cord1.54041959
45MP0002557_abnormal_social/conspecific_i1.47819904
46MP0001984_abnormal_olfaction1.45499558
47MP0004924_abnormal_behavior1.45241984
48MP0005386_behavior/neurological_phenoty1.45241984
49MP0004510_myositis1.44830898
50MP0004885_abnormal_endolymph1.40150992
51MP0008569_lethality_at_weaning1.40142873
52MP0001348_abnormal_lacrimal_gland1.36527523
53MP0003879_abnormal_hair_cell1.35531531
54MP0005195_abnormal_posterior_eye1.32923681
55MP0003633_abnormal_nervous_system1.30870615
56MP0002066_abnormal_motor_capabilities/c1.30782054
57MP0005645_abnormal_hypothalamus_physiol1.29907897
58MP0002090_abnormal_vision1.28361822
59MP0010386_abnormal_urinary_bladder1.27094699
60MP0002653_abnormal_ependyma_morphology1.26767631
61MP0002752_abnormal_somatic_nervous1.25383432
62MP0003283_abnormal_digestive_organ1.23560737
63MP0005646_abnormal_pituitary_gland1.20262843
64MP0004142_abnormal_muscle_tone1.18683660
65MP0003634_abnormal_glial_cell1.16475755
66MP0000751_myopathy1.12285356
67MP0002837_dystrophic_cardiac_calcinosis1.10930238
68MP0005409_darkened_coat_color1.07277739
69MP0004233_abnormal_muscle_weight1.06834580
70MP0004130_abnormal_muscle_cell1.06095418
71MP0001346_abnormal_lacrimal_gland1.04957617
72MP0004742_abnormal_vestibular_system1.04266620
73MP0005394_taste/olfaction_phenotype1.04069027
74MP0005499_abnormal_olfactory_system1.04069027
75MP0003631_nervous_system_phenotype1.02805018
76MP0002152_abnormal_brain_morphology1.00346341
77MP0001324_abnormal_eye_pigmentation1.00067344
78MP0005257_abnormal_intraocular_pressure0.95242802
79MP0001905_abnormal_dopamine_level0.92937596
80MP0003787_abnormal_imprinting0.92204340
81MP0000003_abnormal_adipose_tissue0.89617630
82MP0008961_abnormal_basal_metabolism0.89329139
83MP0001958_emphysema0.88660075
84MP0001299_abnormal_eye_distance/0.88082044
85MP0002069_abnormal_eating/drinking_beha0.87030608
86MP0004145_abnormal_muscle_electrophysio0.86462078
87MP0004043_abnormal_pH_regulation0.85398407
88MP0000604_amyloidosis0.84937903
89MP0001177_atelectasis0.84599485
90MP0001963_abnormal_hearing_physiology0.83126940
91MP0005391_vision/eye_phenotype0.81745429
92MP0010234_abnormal_vibrissa_follicle0.80925475
93MP0005171_absent_coat_pigmentation0.77448657
94MP0001986_abnormal_taste_sensitivity0.76779044
95MP0005535_abnormal_body_temperature0.76647095
96MP0002089_abnormal_postnatal_growth/wei0.75719634
97MP0004085_abnormal_heartbeat0.75325889
98MP0009840_abnormal_foam_cell0.72400735
99MP0001529_abnormal_vocalization0.71654559
100MP0003632_abnormal_nervous_system0.71151668
101MP0005166_decreased_susceptibility_to0.70459347
102MP0008872_abnormal_physiological_respon0.69897704
103MP0003172_abnormal_lysosome_physiology0.69273144
104MP0003690_abnormal_glial_cell0.68666119
105MP0003075_altered_response_to0.65732349
106MP0005623_abnormal_meninges_morphology0.63973606
107MP0000759_abnormal_skeletal_muscle0.63940683
108MP0001849_ear_inflammation0.63715545
109MP0000920_abnormal_myelination0.63699470
110MP0004036_abnormal_muscle_relaxation0.63444305
111MP0002295_abnormal_pulmonary_circulatio0.63417134
112MP0000631_abnormal_neuroendocrine_gland0.63210308
113MP0002751_abnormal_autonomic_nervous0.62367528
114MP0005375_adipose_tissue_phenotype0.61869476
115MP0000749_muscle_degeneration0.61423002
116MP0008874_decreased_physiological_sensi0.60704338
117MP0004215_abnormal_myocardial_fiber0.60016531
118MP0003137_abnormal_impulse_conducting0.59695182
119MP0003045_fibrosis0.54553244
120MP0000747_muscle_weakness0.54371591
121MP0000681_abnormal_thyroid_gland0.54367541
122MP0003453_abnormal_keratinocyte_physiol0.54170050
123MP0005187_abnormal_penis_morphology0.52860515
124MP0004185_abnormal_adipocyte_glucose0.51991416
125MP0002876_abnormal_thyroid_physiology0.51036743
126MP0000569_abnormal_digit_pigmentation0.50621053
127MP0005666_abnormal_adipose_tissue0.50116606

Predicted human phenotypes

RankGene SetZ-score
1Myokymia (HP:0002411)5.48546211
2Focal motor seizures (HP:0011153)5.34859486
3Congenital stationary night blindness (HP:0007642)5.25698141
4Central scotoma (HP:0000603)5.03019286
5Bony spicule pigmentary retinopathy (HP:0007737)4.82013646
6Visual hallucinations (HP:0002367)4.79991348
7Focal seizures (HP:0007359)4.41769506
8Abnormal rod and cone electroretinograms (HP:0008323)4.21981335
9Chorioretinal atrophy (HP:0000533)4.12642142
10Abnormality of binocular vision (HP:0011514)4.04706511
11Diplopia (HP:0000651)4.04706511
12Scotoma (HP:0000575)4.01225220
13Absent rod-and cone-mediated responses on ERG (HP:0007688)3.93500581
14Obstructive sleep apnea (HP:0002870)3.93097028
15Abnormality of macular pigmentation (HP:0008002)3.91562000
16Supranuclear gaze palsy (HP:0000605)3.86994013
17Action tremor (HP:0002345)3.53304560
18Pigmentary retinal degeneration (HP:0001146)3.51791412
19Progressive cerebellar ataxia (HP:0002073)3.47321067
20Febrile seizures (HP:0002373)3.28610244
21Annular pancreas (HP:0001734)3.24387904
22Epileptic encephalopathy (HP:0200134)3.23519345
23Absence seizures (HP:0002121)3.13438352
24Atonic seizures (HP:0010819)3.10755708
25Akinesia (HP:0002304)3.09448801
26Ankle clonus (HP:0011448)3.08497117
27Generalized tonic-clonic seizures (HP:0002069)3.08100603
28Abolished electroretinogram (ERG) (HP:0000550)3.00297140
29Turricephaly (HP:0000262)2.98978390
30Depression (HP:0000716)2.97326751
31Type II diabetes mellitus (HP:0005978)2.95486579
32Posterior subcapsular cataract (HP:0007787)2.89980519
33Apathy (HP:0000741)2.85665620
34Pendular nystagmus (HP:0012043)2.82878359
35Tetraplegia (HP:0002445)2.78126612
36Cerebral hypomyelination (HP:0006808)2.77746275
37Impaired vibration sensation in the lower limbs (HP:0002166)2.77360519
38Mutism (HP:0002300)2.76204998
39Dialeptic seizures (HP:0011146)2.76034288
40Dysdiadochokinesis (HP:0002075)2.74465586
41Truncal ataxia (HP:0002078)2.73437304
42Decreased central vision (HP:0007663)2.73322768
43Urinary bladder sphincter dysfunction (HP:0002839)2.72855386
44Hyperacusis (HP:0010780)2.72724310
45Termporal pattern (HP:0011008)2.68339131
46Insidious onset (HP:0003587)2.68339131
47Poor eye contact (HP:0000817)2.64809379
48Diminished motivation (HP:0000745)2.64488744
49Distal upper limb amyotrophy (HP:0007149)2.62463150
50Upper limb amyotrophy (HP:0009129)2.62463150
51Cone-rod dystrophy (HP:0000548)2.61047913
52Abnormal eating behavior (HP:0100738)2.59384789
53Failure to thrive in infancy (HP:0001531)2.59200530
54Anxiety (HP:0000739)2.57771970
55Dyschromatopsia (HP:0007641)2.56891352
56Rigidity (HP:0002063)2.51532646
57Spastic gait (HP:0002064)2.51347869
58Abnormality of the corticospinal tract (HP:0002492)2.49095198
59Abnormal social behavior (HP:0012433)2.48970648
60Impaired social interactions (HP:0000735)2.48970648
61Abnormality of the lower motor neuron (HP:0002366)2.45283700
62Attenuation of retinal blood vessels (HP:0007843)2.45026860
63Postural instability (HP:0002172)2.42918647
64Lower limb amyotrophy (HP:0007210)2.42893676
65Insomnia (HP:0100785)2.42449871
66Choroideremia (HP:0001139)2.42384442
67Photophobia (HP:0000613)2.41538846
68Hand muscle atrophy (HP:0009130)2.40798128
69Macular degeneration (HP:0000608)2.35635683
70Stridor (HP:0010307)2.34974673
71Broad-based gait (HP:0002136)2.34223045
72Urinary urgency (HP:0000012)2.30755650
73Achilles tendon contracture (HP:0001771)2.29838895
74Cerebral inclusion bodies (HP:0100314)2.27640865
75Retinitis pigmentosa (HP:0000510)2.27056265
76Dysmetria (HP:0001310)2.26612250
77Abnormality of glycolipid metabolism (HP:0010969)2.25137653
78Abnormality of liposaccharide metabolism (HP:0010968)2.25137653
79Abnormality of glycosphingolipid metabolism (HP:0004343)2.25137653
80Agitation (HP:0000713)2.24458658
81Pheochromocytoma (HP:0002666)2.24368362
82Testicular atrophy (HP:0000029)2.23078512
83Torticollis (HP:0000473)2.22403724
84Genetic anticipation (HP:0003743)2.22268430
85Ventricular fibrillation (HP:0001663)2.21801931
86Resting tremor (HP:0002322)2.21672754
87Neurofibrillary tangles (HP:0002185)2.19364853
88Gaze-evoked nystagmus (HP:0000640)2.16789808
89Hyperthyroidism (HP:0000836)2.15618475
90Nuclear cataract (HP:0100018)2.15236730
91Lower limb muscle weakness (HP:0007340)2.13728197
92Polyphagia (HP:0002591)2.12625640
93EEG with generalized epileptiform discharges (HP:0011198)2.10773934
94Amblyopia (HP:0000646)2.10254109
95Cerebral aneurysm (HP:0004944)2.10248254
96Epileptiform EEG discharges (HP:0011182)2.09959078
97Bradykinesia (HP:0002067)2.09609193
98Keratoconus (HP:0000563)2.09463667
99Increased corneal curvature (HP:0100692)2.09463667
100Dysostosis multiplex (HP:0000943)2.09273318
101Abnormality of the Achilles tendon (HP:0005109)2.08861256
102Fetal akinesia sequence (HP:0001989)2.08841304
103Bronchomalacia (HP:0002780)2.08655328
104Clonus (HP:0002169)2.08654341
105Spastic tetraparesis (HP:0001285)2.06123589
106Hypercortisolism (HP:0001578)2.05553941
107Hypsarrhythmia (HP:0002521)2.05548670
108Elevated circulating parathyroid hormone (PTH) level (HP:0003165)2.05454875
109Intention tremor (HP:0002080)2.04680896
110Dementia (HP:0000726)2.04418120
111Centrally nucleated skeletal muscle fibers (HP:0003687)2.04075574
112Abnormality of saccadic eye movements (HP:0000570)2.03932085
113Axonal loss (HP:0003447)2.03044319
114Hypoventilation (HP:0002791)2.02407989
115Sleep apnea (HP:0010535)2.02287433
116Papilledema (HP:0001085)2.01320691
117Exercise-induced myalgia (HP:0003738)2.01290726
118Peripheral hypomyelination (HP:0007182)2.01259490
119Increased cerebral lipofuscin (HP:0011813)2.01139393
120Pointed chin (HP:0000307)2.00048964
121Excessive salivation (HP:0003781)1.96905219
122Drooling (HP:0002307)1.96905219
123Impaired smooth pursuit (HP:0007772)1.95282801
124Bundle branch block (HP:0011710)1.93522121
125Limb ataxia (HP:0002070)1.91127608
126Truncus arteriosus (HP:0001660)1.90406241
127Hyperventilation (HP:0002883)1.89994966
128Distal lower limb amyotrophy (HP:0008944)1.89505718
129Focal dystonia (HP:0004373)1.89253347
130Stereotypic behavior (HP:0000733)1.89240670
131Rapidly progressive (HP:0003678)1.88218487
132Gait imbalance (HP:0002141)1.87952519
133Scanning speech (HP:0002168)1.87089395
134Status epilepticus (HP:0002133)1.86551846
135Dysmetric saccades (HP:0000641)1.86425645
136Spinal cord compression (HP:0002176)1.85644622
137Neuroendocrine neoplasm (HP:0100634)1.85354066
138Abnormality of ocular smooth pursuit (HP:0000617)1.84916333
139Abnormal EKG (HP:0003115)1.84453487
140Loss of speech (HP:0002371)1.84424603
141Megalencephaly (HP:0001355)1.82868175
142Prolonged QT interval (HP:0001657)1.82302120
143Degeneration of the lateral corticospinal tracts (HP:0002314)1.81424625
144Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.81424625
145Hemiparesis (HP:0001269)1.80984297
146Delusions (HP:0000746)1.80015012
147Shallow orbits (HP:0000586)1.79913256
148Vitreoretinal degeneration (HP:0000655)1.79754083
149Constricted visual fields (HP:0001133)1.79311231
150Foot dorsiflexor weakness (HP:0009027)1.79194065
151Craniofacial dystonia (HP:0012179)1.79187298
152Neuronal loss in central nervous system (HP:0002529)1.79124213
153Impaired vibratory sensation (HP:0002495)1.79066818
154Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)1.77430503
155Hyporeflexia of lower limbs (HP:0002600)1.76666513

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NTRK34.25423817
2MAP3K93.65672033
3EPHA43.16822587
4PAK63.14940380
5MAP3K42.98262597
6MARK12.93006634
7MINK12.70358284
8NTRK12.35259632
9TRIB32.26618280
10KSR22.14255485
11PRKD31.99399771
12MAP2K71.90595892
13NTRK21.85069538
14MAP2K41.84417191
15CAMKK11.81413393
16PINK11.79522988
17DAPK21.78603166
18MAP3K21.67588068
19UHMK11.59979787
20RIPK41.53165652
21CDK51.51515675
22GRK51.50394094
23KSR11.47550464
24SIK21.44797857
25RIPK11.42221181
26STK381.39351860
27PHKG11.38103170
28PHKG21.38103170
29LATS21.35240717
30MAP3K121.32028898
31SIK11.31184808
32ICK1.25027184
33TESK11.24832485
34MAPK121.24598025
35SGK2231.23360541
36SGK4941.23360541
37PAK31.21462771
38EEF2K1.19321425
39LMTK21.18601478
40ARAF1.18109611
41PRKCH1.18021976
42NME11.13752315
43PRKD21.12359821
44RET1.10340856
45TYRO31.07682183
46SMG11.06655412
47PRKCG1.06050271
48MAP3K111.02450112
49PNCK1.01802842
50TAOK11.01656862
51DAPK31.01377945
52CASK0.99133889
53WNK10.98254928
54IRAK30.98204070
55CAMKK20.98121673
56PRPF4B0.96593284
57SCYL20.96231362
58FES0.95171411
59ERN10.94618324
60MAPK130.93312995
61CAMK2A0.91664609
62GRK10.90800238
63CDK140.89135808
64CDK180.88755803
65CDK150.87407596
66TNK20.85645554
67CAMK1G0.83518619
68CAMK10.82732652
69PLK20.81977313
70TTN0.81595378
71CDK190.80878416
72STK110.79017847
73DYRK1A0.78821618
74DAPK10.76879102
75MAP3K130.74157872
76CDK11A0.73874069
77ALK0.73280534
78FER0.69701556
79BRAF0.68917912
80FGFR20.67865038
81PRKCZ0.66834448
82SGK20.66248370
83CAMK2B0.66221887
84MARK20.65383266
85SGK30.64550456
86SGK10.64311825
87CAMK2D0.63787356
88PRKG20.63759543
89PDPK10.63589880
90TNIK0.62859551
91CDC42BPA0.62728855
92MAP3K10.61825184
93MAP2K10.59463542
94PDGFRA0.58834093
95MAP2K60.58574086
96TAOK20.58241338
97PDK10.56424552
98INSRR0.55965747
99RPS6KA30.53138480
100MTOR0.52819612
101RAF10.52045825
102SIK30.51253663
103CAMK40.50891879
104NME20.50822154
105BRSK10.50155517
106HIPK20.50078508
107ERBB20.48977087
108PRKCE0.48944457
109MAPK100.48894977
110CAMK2G0.48332750
111RPS6KA20.48049835
112FYN0.47837004
113DMPK0.47451483
114LIMK10.46156481
115ADRBK10.46064940
116PTK20.46010686
117NEK60.45092825
118CSNK1G20.44455656
119CAMK1D0.40882362
120OXSR10.40613060
121ROCK10.40016402
122PRKAA10.39091885
123MOS0.38697696

Predicted pathways (KEGG)

RankGene SetZ-score
1Phototransduction_Homo sapiens_hsa047444.56443329
2Synaptic vesicle cycle_Homo sapiens_hsa047213.44390417
3Nicotine addiction_Homo sapiens_hsa050333.01073754
4Olfactory transduction_Homo sapiens_hsa047402.56730722
5GABAergic synapse_Homo sapiens_hsa047272.55535667
6Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.29514737
7Circadian entrainment_Homo sapiens_hsa047132.27639956
8Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.26157403
9Glutamatergic synapse_Homo sapiens_hsa047242.19307315
10Morphine addiction_Homo sapiens_hsa050322.16356716
11Long-term potentiation_Homo sapiens_hsa047202.10698643
12Insulin secretion_Homo sapiens_hsa049112.04571536
13Dopaminergic synapse_Homo sapiens_hsa047282.03452541
14Amphetamine addiction_Homo sapiens_hsa050311.91417018
15Vitamin B6 metabolism_Homo sapiens_hsa007501.86135898
16Cholinergic synapse_Homo sapiens_hsa047251.84019021
17Salivary secretion_Homo sapiens_hsa049701.76882106
18Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.67200057
19Aldosterone synthesis and secretion_Homo sapiens_hsa049251.60217174
20Cocaine addiction_Homo sapiens_hsa050301.60026522
21Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.59341812
22Gastric acid secretion_Homo sapiens_hsa049711.54884153
23Taste transduction_Homo sapiens_hsa047421.52604224
24Collecting duct acid secretion_Homo sapiens_hsa049661.51160008
25Nitrogen metabolism_Homo sapiens_hsa009101.50408157
26Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.44962859
27Type II diabetes mellitus_Homo sapiens_hsa049301.43756865
28Renin secretion_Homo sapiens_hsa049241.42058217
29Serotonergic synapse_Homo sapiens_hsa047261.39028977
30Oxytocin signaling pathway_Homo sapiens_hsa049211.38163803
31Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.37536127
32Long-term depression_Homo sapiens_hsa047301.28032562
33Glycosaminoglycan degradation_Homo sapiens_hsa005311.25521019
34GnRH signaling pathway_Homo sapiens_hsa049121.23215571
35Phosphatidylinositol signaling system_Homo sapiens_hsa040701.20391827
36Gap junction_Homo sapiens_hsa045401.16608299
37Calcium signaling pathway_Homo sapiens_hsa040201.15839043
38Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.12992715
39cAMP signaling pathway_Homo sapiens_hsa040241.12391491
40Vibrio cholerae infection_Homo sapiens_hsa051101.10837380
41Other glycan degradation_Homo sapiens_hsa005111.09141568
42Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.07136424
43Estrogen signaling pathway_Homo sapiens_hsa049151.00013890
44Axon guidance_Homo sapiens_hsa043600.99033065
45cGMP-PKG signaling pathway_Homo sapiens_hsa040220.98990566
46Glioma_Homo sapiens_hsa052140.97347080
47Melanogenesis_Homo sapiens_hsa049160.92822987
48ErbB signaling pathway_Homo sapiens_hsa040120.87738285
49Carbohydrate digestion and absorption_Homo sapiens_hsa049730.84540040
50Cardiac muscle contraction_Homo sapiens_hsa042600.82223650
51Vascular smooth muscle contraction_Homo sapiens_hsa042700.81353746
52Sulfur relay system_Homo sapiens_hsa041220.78105148
53Pancreatic secretion_Homo sapiens_hsa049720.77635900
54Lysosome_Homo sapiens_hsa041420.75397416
55Phospholipase D signaling pathway_Homo sapiens_hsa040720.74939357
56mTOR signaling pathway_Homo sapiens_hsa041500.73820241
57Circadian rhythm_Homo sapiens_hsa047100.73353076
58Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.72953872
59Thyroid hormone synthesis_Homo sapiens_hsa049180.72200289
60Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.70940860
61Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.70795514
62Glucagon signaling pathway_Homo sapiens_hsa049220.69700332
63Bile secretion_Homo sapiens_hsa049760.65931219
64Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.64804690
65Thyroid hormone signaling pathway_Homo sapiens_hsa049190.64426662
66Choline metabolism in cancer_Homo sapiens_hsa052310.63777540
67Neurotrophin signaling pathway_Homo sapiens_hsa047220.63317960
68Inositol phosphate metabolism_Homo sapiens_hsa005620.62691116
69Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.62489364
70Dilated cardiomyopathy_Homo sapiens_hsa054140.61976939
71Oocyte meiosis_Homo sapiens_hsa041140.61587469
72VEGF signaling pathway_Homo sapiens_hsa043700.60632951
73Prion diseases_Homo sapiens_hsa050200.60344823
74Dorso-ventral axis formation_Homo sapiens_hsa043200.60083001
75Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.56230551
76Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.54926463
77Insulin signaling pathway_Homo sapiens_hsa049100.54094378
78Renal cell carcinoma_Homo sapiens_hsa052110.53557356
79Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.53554403
80Endometrial cancer_Homo sapiens_hsa052130.53476645
81Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.52071556
82Notch signaling pathway_Homo sapiens_hsa043300.52042505
83SNARE interactions in vesicular transport_Homo sapiens_hsa041300.51166987
84MAPK signaling pathway_Homo sapiens_hsa040100.50718452
85Central carbon metabolism in cancer_Homo sapiens_hsa052300.50555837
86Ras signaling pathway_Homo sapiens_hsa040140.48711954
87Arginine biosynthesis_Homo sapiens_hsa002200.46623979
88Longevity regulating pathway - mammal_Homo sapiens_hsa042110.45678501
89Sphingolipid signaling pathway_Homo sapiens_hsa040710.44981666
90Non-small cell lung cancer_Homo sapiens_hsa052230.44771264
912-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.44764536
92Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.44075912
93Glycerophospholipid metabolism_Homo sapiens_hsa005640.42270386
94Rap1 signaling pathway_Homo sapiens_hsa040150.40963419
95Endocytosis_Homo sapiens_hsa041440.40763092
96Sphingolipid metabolism_Homo sapiens_hsa006000.40062044
97Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.39403707
98Alcoholism_Homo sapiens_hsa050340.36282788
99Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.34166955
100Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.34137893
101Focal adhesion_Homo sapiens_hsa045100.33942832
102AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.33317553
103Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.33236933
104Arginine and proline metabolism_Homo sapiens_hsa003300.32854665
105AMPK signaling pathway_Homo sapiens_hsa041520.31902632
106Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.29980972
107Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.29355176
108Maturity onset diabetes of the young_Homo sapiens_hsa049500.28424168
109Wnt signaling pathway_Homo sapiens_hsa043100.27840417
110Prolactin signaling pathway_Homo sapiens_hsa049170.27203239
111Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.26483602
112Glycerolipid metabolism_Homo sapiens_hsa005610.24629994
113Ovarian steroidogenesis_Homo sapiens_hsa049130.24618782
114Type I diabetes mellitus_Homo sapiens_hsa049400.23549926

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