PERP

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of water loss via skin (GO:0033561)9.83015068
2keratinization (GO:0031424)8.80473356
3hemidesmosome assembly (GO:0031581)7.64557570
4bundle of His cell to Purkinje myocyte communication (GO:0086069)7.61626876
5molting cycle (GO:0042303)7.54501841
6hair cycle (GO:0042633)7.54501841
7keratinocyte proliferation (GO:0043616)7.51806254
8keratinocyte differentiation (GO:0030216)7.35542634
9multicellular organismal water homeostasis (GO:0050891)6.78386093
10sphingoid metabolic process (GO:0046519)6.55349770
11gap junction assembly (GO:0016264)6.07771350
12epidermal cell differentiation (GO:0009913)5.89285564
13sphingosine metabolic process (GO:0006670)5.89243511
14intermediate filament organization (GO:0045109)5.85886545
15water homeostasis (GO:0030104)5.81243444
16regulation of phospholipase A2 activity (GO:0032429)5.64403287
17peptide cross-linking (GO:0018149)5.63122811
18epidermis development (GO:0008544)5.37539739
19diol metabolic process (GO:0034311)5.34717984
20polarized epithelial cell differentiation (GO:0030859)5.08303095
21interferon-gamma secretion (GO:0072643)5.04286433
22keratinocyte development (GO:0003334)4.90484436
23surfactant homeostasis (GO:0043129)4.43182601
24skin morphogenesis (GO:0043589)4.40993990
25regulation of ruffle assembly (GO:1900027)4.39395194
26epithelial cell differentiation involved in prostate gland development (GO:0060742)4.35033513
27lateral sprouting from an epithelium (GO:0060601)4.24953178
28regulation of chemokine secretion (GO:0090196)4.19556272
29viral transcription (GO:0019083)4.13239986
30negative regulation of keratinocyte proliferation (GO:0010839)3.97983652
31detection of bacterium (GO:0016045)3.96859980
32ectoderm development (GO:0007398)3.96548749
33regulation of keratinocyte differentiation (GO:0045616)3.96168769
34glucosamine-containing compound catabolic process (GO:1901072)3.95007239
35atrioventricular valve morphogenesis (GO:0003181)3.90655663
36translational termination (GO:0006415)3.88528304
37positive regulation of interleukin-8 secretion (GO:2000484)3.87468204
38positive regulation of epidermal cell differentiation (GO:0045606)3.86942099
39regulation of cell proliferation involved in kidney development (GO:1901722)3.86377601
40negative regulation of cell fate specification (GO:0009996)3.85067890
41dichotomous subdivision of an epithelial terminal unit (GO:0060600)3.81443483
42fatty acid elongation (GO:0030497)3.78696725
43cell adhesion mediated by integrin (GO:0033627)3.63029954
44ribosomal small subunit biogenesis (GO:0042274)3.55169393
45intermediate filament cytoskeleton organization (GO:0045104)3.49501550
46primary alcohol catabolic process (GO:0034310)3.48775047
47regulation of epidermis development (GO:0045682)3.41430190
48intermediate filament-based process (GO:0045103)3.38491553
49linoleic acid metabolic process (GO:0043651)3.37275767
50regulation of cardioblast differentiation (GO:0051890)3.37079974
51long-chain fatty acid biosynthetic process (GO:0042759)3.32910379
52negative regulation of cell fate commitment (GO:0010454)3.31075685
53detection of other organism (GO:0098543)3.30533149
54gland morphogenesis (GO:0022612)3.30353300
55regulation of hair follicle development (GO:0051797)3.28930343
56cardiac right ventricle morphogenesis (GO:0003215)3.28056380
57negative regulation of lipase activity (GO:0060192)3.27211108
58regulation of interleukin-8 secretion (GO:2000482)3.25031064
59regulation of transforming growth factor beta1 production (GO:0032908)3.24875404
60regulation of Wnt signaling pathway involved in heart development (GO:0003307)3.19469143
61phosphatidylinositol acyl-chain remodeling (GO:0036149)3.17771606
62negative regulation of stress fiber assembly (GO:0051497)3.16402231
63regulation of transforming growth factor beta2 production (GO:0032909)3.15725558
64hypotonic response (GO:0006971)3.15490368
65positive regulation of chemokine secretion (GO:0090197)3.12764040
66positive regulation of keratinocyte differentiation (GO:0045618)3.09852765
67ventricular cardiac muscle cell action potential (GO:0086005)3.09760720
68planar cell polarity pathway involved in neural tube closure (GO:0090179)3.07855002
69regulation of epidermal cell differentiation (GO:0045604)3.06372471
70cell-cell junction assembly (GO:0007043)3.05179623
71regulation of hypersensitivity (GO:0002883)3.03421143
72SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.03288223
73translational elongation (GO:0006414)3.03091542
74eyelid development in camera-type eye (GO:0061029)3.02104671
75viral life cycle (GO:0019058)3.01755867
76intestinal epithelial cell development (GO:0060576)3.01647348
77negative regulation of interferon-gamma production (GO:0032689)2.99240350
78protein targeting to ER (GO:0045047)2.99049230
79phosphatidylserine acyl-chain remodeling (GO:0036150)2.97123808
80cotranslational protein targeting to membrane (GO:0006613)2.94701151
81positive regulation of epidermis development (GO:0045684)2.94422966
82regulation of glomerular filtration (GO:0003093)2.94045608
83prostaglandin biosynthetic process (GO:0001516)2.92512697
84prostanoid biosynthetic process (GO:0046457)2.92512697
85establishment of protein localization to endoplasmic reticulum (GO:0072599)2.91901752
86cell junction assembly (GO:0034329)2.91672139
87retinal metabolic process (GO:0042574)2.90925390
88COPI coating of Golgi vesicle (GO:0048205)2.90754166
89Golgi transport vesicle coating (GO:0048200)2.90754166
90epithelial cell-cell adhesion (GO:0090136)2.89942131
91ethanol metabolic process (GO:0006067)2.88574871
92negative regulation of kidney development (GO:0090185)2.88322838
93positive regulation of hair follicle development (GO:0051798)2.86439699
94positive regulation of hair cycle (GO:0042635)2.86439699
95heart valve morphogenesis (GO:0003179)2.86020303
96negative regulation of chondrocyte differentiation (GO:0032331)2.85709054
97cyclooxygenase pathway (GO:0019371)2.85072040
98hair follicle morphogenesis (GO:0031069)2.85051583
99cellular protein complex disassembly (GO:0043624)2.84606943
100morphogenesis of embryonic epithelium (GO:0016331)2.84335398
101response to phenylpropanoid (GO:0080184)2.82653612
102phospholipid efflux (GO:0033700)2.82650950
103protein localization to endosome (GO:0036010)2.82469485
104fibrinolysis (GO:0042730)2.80191061
105negative regulation of epidermis development (GO:0045683)2.79571408
106mesodermal cell differentiation (GO:0048333)2.78705828
107regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.77489574
108chemical homeostasis within a tissue (GO:0048875)2.76915368
109protein localization to endoplasmic reticulum (GO:0070972)2.76354811
110skin development (GO:0043588)2.76318393
111hair cycle process (GO:0022405)2.76104082
112molting cycle process (GO:0022404)2.76104082
113epithelium development (GO:0060429)2.75610427
114cytoskeletal anchoring at plasma membrane (GO:0007016)2.73600193
115negative regulation of interleukin-2 production (GO:0032703)2.73445580
116* cell junction organization (GO:0034330)2.73192150
117long-chain fatty-acyl-CoA metabolic process (GO:0035336)2.69266390
118adhesion of symbiont to host cell (GO:0044650)2.67124930
119virion attachment to host cell (GO:0019062)2.67124930
120phospholipid scrambling (GO:0017121)2.66719532
121nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.66654163
122regulation of cholesterol homeostasis (GO:2000188)2.62507663
123Wnt signaling pathway, planar cell polarity pathway (GO:0060071)2.62373839
124cardiolipin metabolic process (GO:0032048)2.61982089
125lipoxygenase pathway (GO:0019372)2.61259728
126regulation of hair cycle (GO:0042634)2.59949069
127cellular component disassembly involved in execution phase of apoptosis (GO:0006921)2.59580336
128phosphatidylethanolamine acyl-chain remodeling (GO:0036152)2.59135419
129negative regulation of stem cell proliferation (GO:2000647)2.59074103
130negative regulation of T cell mediated immunity (GO:0002710)2.58937885
131prostanoid metabolic process (GO:0006692)2.57989759
132prostaglandin metabolic process (GO:0006693)2.57989759
133regulation of heart rate by cardiac conduction (GO:0086091)2.57303764
134establishment of planar polarity (GO:0001736)2.56382117
135establishment of tissue polarity (GO:0007164)2.56382117
136cell-substrate junction assembly (GO:0007044)2.56192911
137regulation of establishment of planar polarity (GO:0090175)2.55748020
138hair follicle development (GO:0001942)2.53455342
139regulation of keratinocyte proliferation (GO:0010837)2.53361096
140cell communication involved in cardiac conduction (GO:0086065)2.53285316
141apical protein localization (GO:0045176)2.51550935
142regulation of transforming growth factor beta production (GO:0071634)2.50624953
143tight junction assembly (GO:0070830)2.49726272
144epithelial cell proliferation (GO:0050673)2.49661739
145endodermal cell differentiation (GO:0035987)2.48634962
146mammary gland epithelial cell proliferation (GO:0033598)2.48184659
147establishment of apical/basal cell polarity (GO:0035089)2.41419122
148mitotic G1 DNA damage checkpoint (GO:0031571)2.41231629
149regulation of tight junction assembly (GO:2000810)2.38475953
150epithelial cell maturation (GO:0002070)2.36251165
151wound healing (GO:0042060)2.36023518
152* desmosome organization (GO:0002934)12.1185716
153establishment of skin barrier (GO:0061436)10.4579134

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1* TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse6.24419020
2* SOX9_24532713_ChIP-Seq_HFSC_Mouse3.04589119
3* P63_26484246_Chip-Seq_KERATINOCYTES_Human3.01766615
4ESR1_21235772_ChIP-Seq_MCF-7_Human2.82270731
5ZNF263_19887448_ChIP-Seq_K562_Human2.66888641
6SMAD4_19686287_ChIP-ChIP_HaCaT_Human2.54837643
7TRIM28_21343339_ChIP-Seq_HEK293_Human2.44746546
8ESR2_21235772_ChIP-Seq_MCF-7_Human2.31735158
9ESR1_17901129_ChIP-ChIP_LIVER_Mouse2.18343309
10* SMAD3_18955504_ChIP-ChIP_HaCaT_Human2.16083063
11* SMAD2_18955504_ChIP-ChIP_HaCaT_Human2.16083063
12STAT6_21828071_ChIP-Seq_BEAS2B_Human2.04951408
13CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.03501429
14TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.01063350
15* TP63_17297297_ChIP-ChIP_HaCaT_Human14.0226115
16PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.86674912
17* FOXO3_23340844_ChIP-Seq_DLD1_Human1.78812064
18PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.76578352
19SOX2_20726797_ChIP-Seq_SW620_Human1.74458889
20* PPARA_22158963_ChIP-Seq_LIVER_Mouse1.64135158
21* ZNF217_24962896_ChIP-Seq_MCF-7_Human1.61050398
22AR_21909140_ChIP-Seq_LNCAP_Human1.60029442
23RARG_19884340_ChIP-ChIP_MEFs_Mouse1.57501408
24TCF4_18268006_ChIP-ChIP_LS174T_Human1.55555473
25* RXR_22158963_ChIP-Seq_LIVER_Mouse1.50215715
26* TP63_23658742_ChIP-Seq_EP156T_Human1.45620074
27RUNX1_27514584_Chip-Seq_MCF-7_Human1.42654345
28CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.41237687
29ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.40451673
30* STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.37587912
31* CJUN_26792858_Chip-Seq_BT549_Human1.34104116
32* GATA4_25053715_ChIP-Seq_YYC3_Human1.34057166
33CDX2_20551321_ChIP-Seq_CACO-2_Human1.32666994
34KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.32214093
35* BMI1_19503595_ChIP-Seq_MEFsC_Mouse1.30320954
36KLF5_25053715_ChIP-Seq_YYC3_Human1.30067731
37KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.29570786
38TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.29196774
39HIF1A_21447827_ChIP-Seq_MCF-7_Human1.28923163
40LXR_22158963_ChIP-Seq_LIVER_Mouse1.26037875
41* TP63_22573176_ChIP-Seq_HFKS_Human1.24583330
42FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.24516633
43TP53_18474530_ChIP-ChIP_U2OS_Human1.22997658
44CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.22843954
45RACK7_27058665_Chip-Seq_MCF-7_Human1.20552568
46NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.19748376
47PPAR_26484153_Chip-Seq_NCI-H1993_Human1.19723797
48TP53_20018659_ChIP-ChIP_R1E_Mouse1.18810662
49AR_21572438_ChIP-Seq_LNCaP_Human1.16408146
50P300_27058665_Chip-Seq_ZR-75-30cells_Human1.16021910
51SOX2_27498859_Chip-Seq_STOMACH_Mouse1.13287893
52RXR_22108803_ChIP-Seq_LS180_Human1.13080385
53GATA6_25053715_ChIP-Seq_YYC3_Human1.12355105
54* ATF3_27146783_Chip-Seq_COLON_Human1.11917745
55* ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.10889787
56* EOMES_20176728_ChIP-ChIP_TSCs_Mouse1.10269588
57FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.10263848
58* GATA3_24758297_ChIP-Seq_MCF-7_Human1.09059183
59EGR1_23403033_ChIP-Seq_LIVER_Mouse1.08106454
60GATA6_21074721_ChIP-Seq_CACO-2_Mouse1.00306410
61SRY_22984422_ChIP-ChIP_TESTIS_Rat0.99924969
62UBF1/2_26484160_Chip-Seq_HMECs_Human0.99743214
63GATA1_22025678_ChIP-Seq_K562_Human0.99639758
64RUNX2_24764292_ChIP-Seq_MC3T3_Mouse0.97990899
65BCAT_22108803_ChIP-Seq_LS180_Human0.96015601
66ELK3_25401928_ChIP-Seq_HUVEC_Human0.95748314
67* TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.95340291
68CEBPB_22108803_ChIP-Seq_LS180_Human0.94671103
69* AHR_22903824_ChIP-Seq_MCF-7_Human0.93636372
70HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.93410635
71CLOCK_20551151_ChIP-Seq_293T_Human0.93078998
72ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.92696561
73CHD1_26751641_Chip-Seq_LNCaP_Human0.92395469
74ESR1_20079471_ChIP-ChIP_T-47D_Human0.92333031
75KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.91568573
76ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.91275668
77UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.88583736
78CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.87156931
79TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse0.86572380
80NR1I2_20693526_ChIP-Seq_LIVER_Mouse0.85650977
81FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.84529706
82TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.83442509
83TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.82308611
84JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.82156210
85* ATF3_23680149_ChIP-Seq_GBM1-GSC_Human0.82057540
86BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.81252567
87GATA6_21074721_ChIP-Seq_CACO-2_Human0.80641707
88WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.80214893
89P63_20808887_ChIP-Seq_KERATINOCYTES_Human0.78721128
90* FOXM1_26456572_ChIP-Seq_MCF-7_Human0.78459051
91TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.78451035
92EGR1_19032775_ChIP-ChIP_M12_Human0.78180349
93LXR_22292898_ChIP-Seq_THP-1_Human0.78121311
94KLF4_18555785_ChIP-Seq_MESCs_Mouse0.77011153
95POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.76913399
96* NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.76831644
97SA1_27219007_Chip-Seq_ERYTHROID_Human0.74079699
98FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.73954562
99RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.73763674
100CTCF_27219007_Chip-Seq_Bcells_Human0.72771536
101AUTS2_25519132_ChIP-Seq_293T-REX_Human0.72562157
102GATA3_20176728_ChIP-ChIP_TSCs_Mouse0.71988377
103JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.71960271
104FOXA1_26743006_Chip-Seq_LNCaP-abl_Human0.71909030
105ERG_21242973_ChIP-ChIP_JURKAT_Human0.71722504
106SALL4_18804426_ChIP-ChIP_XEN_Mouse0.70886440
107TBX20_22328084_ChIP-Seq_HEART_Mouse0.69562975
108TBX20_22080862_ChIP-Seq_HEART_Mouse0.69562975
109ZIC3_20872845_ChIP-ChIP_MESCs_Mouse0.68859481
110BRD4_25478319_ChIP-Seq_HGPS_Human0.68351704
111EP300_21415370_ChIP-Seq_HL-1_Mouse0.67752641
112VDR_22108803_ChIP-Seq_LS180_Human0.67569646
113TP53_22127205_ChIP-Seq_IMR90_Human0.67053305
114SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.66109037
115TP53_16413492_ChIP-PET_HCT116_Human0.64614944
116* TCF4_22108803_ChIP-Seq_LS180_Human0.64548641
117AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.64413807
118* SUZ12_27294783_Chip-Seq_ESCs_Mouse0.64076283
119GATA2_21666600_ChIP-Seq_HMVEC_Human0.63448528
120CDX2_21074721_ChIP-Seq_CACO-2_Mouse0.63215339
121NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.62786070
122NRF2_20460467_ChIP-Seq_MEFs_Mouse0.62786070
123EED_16625203_ChIP-ChIP_MESCs_Mouse0.62582075
124* ARNT_22903824_ChIP-Seq_MCF-7_Human0.62015607
125SUZ12_16625203_ChIP-ChIP_MESCs_Mouse0.61133610
126EZH2_27304074_Chip-Seq_ESCs_Mouse0.61090936
127SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.59910122
128CDX2_19796622_ChIP-Seq_MESCs_Mouse0.59587992

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002796_impaired_skin_barrier7.17465053
2MP0010234_abnormal_vibrissa_follicle5.92200195
3MP0005275_abnormal_skin_tensile5.28349508
4MP0003941_abnormal_skin_development4.80834773
5MP0005501_abnormal_skin_physiology4.41795160
6MP0000579_abnormal_nail_morphology3.98517268
7MP0004381_abnormal_hair_follicle3.70838723
8MP0002098_abnormal_vibrissa_morphology3.54077255
9MP0002254_reproductive_system_inflammat3.44505935
10MP0002060_abnormal_skin_morphology3.43312592
11MP0010678_abnormal_skin_adnexa3.41793180
12MP0000383_abnormal_hair_follicle3.40799018
13MP0001216_abnormal_epidermal_layer3.36984175
14MP0003453_abnormal_keratinocyte_physiol3.12734862
15MP0000647_abnormal_sebaceous_gland2.90574914
16MP0010771_integument_phenotype2.86555936
17MP0000377_abnormal_hair_follicle2.68385679
18MP0000467_abnormal_esophagus_morphology2.38061140
19MP0003705_abnormal_hypodermis_morpholog2.33505528
20MP0000566_synostosis2.27502036
21MP0004947_skin_inflammation2.25517056
22MP0000427_abnormal_hair_cycle2.23740683
23MP0003566_abnormal_cell_adhesion1.96249495
24MP0005451_abnormal_body_composition1.95212985
25MP0000762_abnormal_tongue_morphology1.85159644
26MP0001346_abnormal_lacrimal_gland1.82853348
27MP0002009_preneoplasia1.81244344
28MP0009379_abnormal_foot_pigmentation1.71208768
29MP0009780_abnormal_chondrocyte_physiolo1.67959762
30MP0009931_abnormal_skin_appearance1.63488390
31MP0001191_abnormal_skin_condition1.56613027
32MP0004185_abnormal_adipocyte_glucose1.49861849
33MP0000367_abnormal_coat/_hair1.45616230
34MP0001243_abnormal_dermal_layer1.41368736
35MP0010352_gastrointestinal_tract_polyps1.26033355
36MP0009053_abnormal_anal_canal1.19485974
37MP0002234_abnormal_pharynx_morphology1.14733935
38MP0008438_abnormal_cutaneous_collagen1.13950056
39MP0005257_abnormal_intraocular_pressure1.11791144
40MP0001188_hyperpigmentation1.09595365
41MP0003011_delayed_dark_adaptation1.07167838
42MP0004019_abnormal_vitamin_homeostasis1.06222974
43MP0001340_abnormal_eyelid_morphology1.05758340
44MP0001851_eye_inflammation1.03732413
45MP0003191_abnormal_cellular_cholesterol1.02941530
46MP0005085_abnormal_gallbladder_physiolo0.99911187
47MP0005023_abnormal_wound_healing0.91535061
48MP0000537_abnormal_urethra_morphology0.89444152
49MP0000678_abnormal_parathyroid_gland0.88886610
50MP0009384_cardiac_valve_regurgitation0.83981130
51MP0002877_abnormal_melanocyte_morpholog0.82541206
52MP0001666_abnormal_nutrient_absorption0.80063427
53MP0000627_abnormal_mammary_gland0.79099936
54MP0004264_abnormal_extraembryonic_tissu0.77008799
55MP0000516_abnormal_urinary_system0.74992924
56MP0005367_renal/urinary_system_phenotyp0.74992924
57MP0005360_urolithiasis0.72454717
58MP0004782_abnormal_surfactant_physiolog0.71738304
59MP0010030_abnormal_orbit_morphology0.70349975
60MP0003315_abnormal_perineum_morphology0.70255351
61MP0000462_abnormal_digestive_system0.69837879
62MP0008875_abnormal_xenobiotic_pharmacok0.69575693
63MP0002249_abnormal_larynx_morphology0.68506898
64MP0004272_abnormal_basement_membrane0.68259512
65MP0008004_abnormal_stomach_pH0.67503285
66MP0004885_abnormal_endolymph0.66857943
67MP0005076_abnormal_cell_differentiation0.64805249
68MP0000465_gastrointestinal_hemorrhage0.63805589
69MP0003136_yellow_coat_color0.62216514
70MP0002166_altered_tumor_susceptibility0.61207310
71MP0002006_tumorigenesis0.61035422
72MP0000538_abnormal_urinary_bladder0.60787064
73MP0001849_ear_inflammation0.59882597
74MP0008260_abnormal_autophagy0.59533849
75MP0002282_abnormal_trachea_morphology0.59504294
76MP0003878_abnormal_ear_physiology0.58335179
77MP0005377_hearing/vestibular/ear_phenot0.58335179
78MP0000858_altered_metastatic_potential0.57364672
79MP0005197_abnormal_uvea_morphology0.57356291
80MP0001299_abnormal_eye_distance/0.56751094
81MP0008789_abnormal_olfactory_epithelium0.56182648
82MP0002177_abnormal_outer_ear0.53848242
83MP0003755_abnormal_palate_morphology0.50727755
84MP0001784_abnormal_fluid_regulation0.49415145
85MP0002111_abnormal_tail_morphology0.48292687
86MP0005508_abnormal_skeleton_morphology0.48189570
87MP0005623_abnormal_meninges_morphology0.47614573
88MP0001881_abnormal_mammary_gland0.46364368
89MP0005409_darkened_coat_color0.45161836
90MP0005193_abnormal_anterior_eye0.44746311
91MP0003950_abnormal_plasma_membrane0.44450182
92MP0006138_congestive_heart_failure0.43893212
93MP0000613_abnormal_salivary_gland0.43747073
94MP0000428_abnormal_craniofacial_morphol0.43491545
95MP0005248_abnormal_Harderian_gland0.43255497
96MP0005666_abnormal_adipose_tissue0.43069364
97MP0005187_abnormal_penis_morphology0.42015582
98MP0005503_abnormal_tendon_morphology0.41011939
99MP0000003_abnormal_adipose_tissue0.40518623
100MP0005408_hypopigmentation0.39144714
101MP0003638_abnormal_response/metabolism_0.38032193
102MP0002233_abnormal_nose_morphology0.37347689
103MP0002089_abnormal_postnatal_growth/wei0.37232944
104MP0005365_abnormal_bile_salt0.36848109
105MP0003091_abnormal_cell_migration0.35273048
106MP0000470_abnormal_stomach_morphology0.33882970
107MP0009250_abnormal_appendicular_skeleto0.33427502
108MP0002277_abnormal_respiratory_mucosa0.33356644
109MP0004197_abnormal_fetal_growth/weight/0.32952374
110MP0005075_abnormal_melanosome_morpholog0.32418642
111MP0002139_abnormal_hepatobiliary_system0.32084890
112MP0003436_decreased_susceptibility_to0.31499681
113MP0005499_abnormal_olfactory_system0.31323811
114MP0005394_taste/olfaction_phenotype0.31323811
115MP0005621_abnormal_cell_physiology0.30403957
116MP0002095_abnormal_skin_pigmentation0.30222102
117MP0005647_abnormal_sex_gland0.29417991
118MP0004957_abnormal_blastocyst_morpholog0.29366482
119MP0005165_increased_susceptibility_to0.29194821
120MP0000432_abnormal_head_morphology0.28989567
121MP0004858_abnormal_nervous_system0.27684507
122MP0001958_emphysema0.27581041
123MP0009840_abnormal_foam_cell0.27567874
124MP0003828_pulmonary_edema0.27274530
125MP0003936_abnormal_reproductive_system0.26700438
126MP0003195_calcinosis0.26562051
127MP0002896_abnormal_bone_mineralization0.25759812
128MP0005375_adipose_tissue_phenotype0.25528278
129MP0002697_abnormal_eye_size0.25120864
130MP0003385_abnormal_body_wall0.25007221
131MP0001984_abnormal_olfaction0.24802709

Predicted human phenotypes

RankGene SetZ-score
1Hypotrichosis (HP:0001006)7.71015683
2Right ventricular cardiomyopathy (HP:0011663)7.00144104
3Woolly hair (HP:0002224)6.89547780
4Plantar hyperkeratosis (HP:0007556)6.35250493
5Parakeratosis (HP:0001036)5.92064945
6Onycholysis (HP:0001806)5.84481786
7Palmoplantar hyperkeratosis (HP:0000972)5.75653601
8Fragile nails (HP:0001808)5.73156285
9Congenital ichthyosiform erythroderma (HP:0007431)5.69790358
10Increased IgE level (HP:0003212)5.65651399
11Congenital nonbullous ichthyosiform erythroderma (HP:0007479)5.50861969
12Lip pit (HP:0100267)5.45104466
13Palmar hyperkeratosis (HP:0010765)5.41547942
14Abnormality of nail color (HP:0100643)5.34817917
15Erythema (HP:0010783)4.99170425
16Erythroderma (HP:0001019)4.77070055
17Pili torti (HP:0003777)4.67381971
18Milia (HP:0001056)4.38857853
19Abnormality of secondary sexual hair (HP:0009888)4.15685138
20Abnormality of the axillary hair (HP:0100134)4.15685138
21Abnormal blistering of the skin (HP:0008066)3.99380915
22Conjunctival hamartoma (HP:0100780)3.90306559
23Nail dystrophy (HP:0008404)3.80541295
24Natal tooth (HP:0000695)3.77760994
25Selective tooth agenesis (HP:0001592)3.74292858
26Ventricular tachycardia (HP:0004756)3.72530746
27Sparse eyelashes (HP:0000653)3.67884581
28Thick nail (HP:0001805)3.59123800
29Sparse scalp hair (HP:0002209)3.58009674
30Oral leukoplakia (HP:0002745)3.51169959
31Popliteal pterygium (HP:0009756)3.40248901
32Advanced eruption of teeth (HP:0006288)3.35048297
33Acanthosis nigricans (HP:0000956)3.29353920
34Hyporeflexia of lower limbs (HP:0002600)3.17833828
35Ectropion (HP:0000656)3.10007975
36Curly hair (HP:0002212)3.09749213
37Palmoplantar keratoderma (HP:0000982)3.09328377
38Distal lower limb muscle weakness (HP:0009053)3.07116690
39Corneal erosion (HP:0200020)3.03155527
40Hypohidrosis (HP:0000966)3.02218131
41Alopecia of scalp (HP:0002293)2.95579640
42Abnormal hair laboratory examination (HP:0003328)2.94657437
43Pruritus (HP:0000989)2.81091964
44Atrophic scars (HP:0001075)2.78417704
45Brittle hair (HP:0002299)2.72247306
46Gangrene (HP:0100758)2.71537133
47Abnormality of permanent molar morphology (HP:0011071)2.69126570
48Abnormality of the dental root (HP:0006486)2.69126570
49Taurodontia (HP:0000679)2.69126570
50Congenital, generalized hypertrichosis (HP:0004540)2.68765727
51Hypoplastic labia majora (HP:0000059)2.63341223
52Aplasia cutis congenita (HP:0001057)2.61248625
53Abnormality of molar (HP:0011077)2.53359652
54Abnormality of molar morphology (HP:0011070)2.53359652
55Ridged nail (HP:0001807)2.52289853
56Abnormal hemoglobin (HP:0011902)2.45707338
57Absent hair (HP:0002298)2.44295368
58Ventricular fibrillation (HP:0001663)2.43338378
59Abnormality of the salivary glands (HP:0010286)2.36788691
60Abnormality of the labia majora (HP:0012881)2.36774456
61Abnormality of the dental pulp (HP:0006479)2.35819864
62Concave nail (HP:0001598)2.32740481
63Pterygium (HP:0001059)2.28293490
64Nasolacrimal duct obstruction (HP:0000579)2.27364019
65Ankyloglossia (HP:0010296)2.26378641
66Abnormality of the gastric mucosa (HP:0004295)2.24106601
67Hamartoma of the eye (HP:0010568)2.18463676
68Oligodontia (HP:0000677)2.17599301
69Amniotic constriction ring (HP:0009775)2.15869360
70Abnormality of placental membranes (HP:0011409)2.15869360
71Abnormality of cells of the erythroid lineage (HP:0012130)2.12899842
72Reticulocytopenia (HP:0001896)2.11445401
73Amelogenesis imperfecta (HP:0000705)2.02955089
74Sudden death (HP:0001699)2.02531927
75Dehydration (HP:0001944)2.01908096
76Neonatal death (HP:0003811)2.00530045
77Hyperhidrosis (HP:0000975)1.97581891
78Down-sloping shoulders (HP:0200021)1.97241486
79Dry skin (HP:0000958)1.96828280
80Areflexia of lower limbs (HP:0002522)1.96758262
81Abnormality of hair growth rate (HP:0011363)1.96577134
82Slow-growing hair (HP:0002217)1.96577134
83Carious teeth (HP:0000670)1.94887709
84Aplasia/Hypoplasia of the phalanges of the toes (HP:0010173)1.93645295
85Xerostomia (HP:0000217)1.93627555
86Hypoplasia of dental enamel (HP:0006297)1.92628240
87Abnormality of the distal phalanges of the toes (HP:0010182)1.91444354
88Xanthomatosis (HP:0000991)1.90141746
89Abnormality of the lacrimal duct (HP:0011481)1.87879281
90Anhidrosis (HP:0000970)1.85809381
91Severe Myopia (HP:0011003)1.84100364
92Blepharitis (HP:0000498)1.83823039
93Split foot (HP:0001839)1.83165211
94Laryngomalacia (HP:0001601)1.80686084
95Fragile skin (HP:0001030)1.79710747
96Dry hair (HP:0011359)1.79470822
97Skin pits (HP:0100276)1.79377610
98Absent eyebrow (HP:0002223)1.78956729
99Intrahepatic cholestasis (HP:0001406)1.77803010
100Hypodontia (HP:0000668)1.77573347
101Increased connective tissue (HP:0009025)1.75739308
102Abnormal number of erythroid precursors (HP:0012131)1.71383610
103Septate vagina (HP:0001153)1.70507061
104Follicular hyperkeratosis (HP:0007502)1.69600194
105Abnormality of the fingernails (HP:0001231)1.69431524
106Abnormality of oral frenula (HP:0000190)1.69096626
107Hypoplastic female external genitalia (HP:0012815)1.67408307
108Abnormality of the nasolacrimal system (HP:0000614)1.66060520
109Short nail (HP:0001799)1.65374612
110Aplasia involving bones of the extremities (HP:0009825)1.64860203
111Aplasia involving bones of the upper limbs (HP:0009823)1.64860203
112Aplasia of the phalanges of the hand (HP:0009802)1.64860203
113Breast hypoplasia (HP:0003187)1.63182037
114Anonychia (HP:0001798)1.62850844
115Melanocytic nevus (HP:0000995)1.60555917
116Vascular calcification (HP:0004934)1.60353408
117Bifid scrotum (HP:0000048)1.60276013
118Corneal dystrophy (HP:0001131)1.59907715
119Macrocytic anemia (HP:0001972)1.59820744
120Conical tooth (HP:0000698)1.59701190
121Epidermoid cyst (HP:0200040)1.59174623
122Abnormality of the 2nd finger (HP:0004100)1.58830478
123Achilles tendon contracture (HP:0001771)1.58731733
124Abnormality of the Achilles tendon (HP:0005109)1.58500779
125Trismus (HP:0000211)1.57664764
126Osteolytic defects of the phalanges of the hand (HP:0009771)1.55557827
127Osteolytic defects of the hand bones (HP:0009699)1.55557827
128Pustule (HP:0200039)1.51922066
129Labial hypoplasia (HP:0000066)1.51688050
130Skin ulcer (HP:0200042)1.51596764
131Fatigable weakness (HP:0003473)1.50979133
132Abnormality of the neuromuscular junction (HP:0003398)1.50979133
133Hypergammaglobulinemia (HP:0010702)1.50793461
134Absent eyelashes (HP:0000561)1.49965858

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MST1R5.43380926
2MAPKAPK34.71505160
3MAP3K34.27896679
4MST44.07209774
5FER3.34808368
6MAP3K22.86343522
7RPS6KB22.83756742
8EPHB22.68328674
9LATS12.48566829
10EPHA22.45584749
11TRPM72.33446662
12ERN12.27387979
13PIK3CG2.06598299
14PIM21.87370206
15MET1.84501533
16STK241.74043296
17LMTK21.72621022
18LRRK21.70404562
19PAK41.64953202
20ARAF1.60350244
21MAP3K121.56888961
22STK101.54854636
23FGFR41.53671481
24BCR1.51678926
25PTK61.51393341
26EEF2K1.50919961
27PDGFRA1.50704038
28FGFR21.47398879
29NTRK11.43780513
30MAPKAPK51.31809160
31SMG11.31763648
32EPHA31.29661551
33CDK121.29058795
34ERBB31.26558813
35FRK1.25780722
36MAP3K111.12730711
37DYRK1B1.11050991
38CDK31.11026262
39TTN1.08585154
40TESK11.04025086
41TGFBR21.01603817
42MYLK0.95935350
43MAP3K10.93366007
44MAPK150.93120039
45CDK60.92121288
46ICK0.90988168
47TAOK10.89884035
48MAP2K20.89012600
49FGFR30.87976645
50GRK70.84203465
51MAP2K60.80356230
52MAP3K70.79972040
53MAPKAPK20.76852018
54RPS6KA40.76490378
55STK38L0.75772028
56GRK10.73704305
57MAP3K140.69714920
58TYK20.68726764
59STK380.68414403
60BLK0.67703208
61PRKD10.67417488
62EPHB10.66533643
63FLT30.65577216
64MAPK70.65399925
65DMPK0.64423241
66BCKDK0.63034278
67NME20.62306497
68ERBB20.62285768
69NEK60.61909890
70LATS20.61862249
71PTK20.61302165
72MTOR0.59816011
73MAP3K50.58852697
74BMPR1B0.58786986
75FGFR10.58545269
76PRKCI0.56532341
77MAP2K10.55558681
78OBSCN0.55095574
79SIK10.54419713
80ERBB40.54222675
81PDGFRB0.54119774
82SCYL20.53069462
83PKN20.52493139
84BRSK20.49146042
85RPS6KB10.48732615
86RIPK10.48518584
87PBK0.48296157
88TRIB30.47106570
89PAK30.46036240
90PRKCE0.45120065
91MAPK110.44640963
92ROCK10.44449989
93ADRBK10.44187130
94RPS6KA20.42008271
95ABL20.40107425
96PDK20.40063428
97STK30.39475372
98KSR20.38762648
99RPS6KA10.38660903
100ITK0.38102891
101NTRK20.37998629
102SIK30.37677766
103BMX0.36890176
104STK390.36806594
105EIF2AK10.36752677
106JAK20.36434860
107IKBKB0.36024236
108TGFBR10.35690808
109ILK0.34790761
110ROCK20.34577206
111CSNK1D0.33360246
112NME10.32199235
113MAP3K90.30687129
114CDC42BPA0.30649522
115RET0.29858198
116EIF2AK20.29293083
117GSK3A0.29286139
118PRKD20.28556211
119TTK0.28134944
120LIMK10.27992955
121MAPK120.27799501
122IRAK30.27330242
123BRAF0.25392677
124IKBKE0.25389676
125NLK0.25194931
126MAP2K30.23940529
127BRD40.22510716
128PKN10.22380130
129MOS0.21988533
130ABL10.21125978
131MAP3K60.21062903
132PAK20.20322813
133AKT30.20144155
134TAOK20.20119316
135CHUK0.19740717
136IGF1R0.19675184
137STK110.19409251
138DYRK30.19223644
139CDK70.19079382
140MAP3K80.18087170

Predicted pathways (KEGG)

RankGene SetZ-score
1Cyanoamino acid metabolism_Homo sapiens_hsa004603.88745639
2Ribosome_Homo sapiens_hsa030103.10581306
3Linoleic acid metabolism_Homo sapiens_hsa005912.88975022
4Sphingolipid metabolism_Homo sapiens_hsa006002.84121247
5alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.80104906
6Fatty acid elongation_Homo sapiens_hsa000622.70890497
7Phenylalanine metabolism_Homo sapiens_hsa003602.66656433
8Histidine metabolism_Homo sapiens_hsa003402.44797654
9Retinol metabolism_Homo sapiens_hsa008302.41472872
10Drug metabolism - cytochrome P450_Homo sapiens_hsa009822.38705874
11Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.35878832
12Arachidonic acid metabolism_Homo sapiens_hsa005902.30852961
13Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009802.28442946
14Chemical carcinogenesis_Homo sapiens_hsa052042.11935727
15Caffeine metabolism_Homo sapiens_hsa002322.01829197
16Basal cell carcinoma_Homo sapiens_hsa052171.92833653
17Primary bile acid biosynthesis_Homo sapiens_hsa001201.76463281
18Tyrosine metabolism_Homo sapiens_hsa003501.72463628
19Fatty acid degradation_Homo sapiens_hsa000711.61167348
20Fat digestion and absorption_Homo sapiens_hsa049751.58581618
21Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.56337373
22Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.54187036
23Adherens junction_Homo sapiens_hsa045201.43420670
24Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.41583607
25beta-Alanine metabolism_Homo sapiens_hsa004101.41023178
26Staphylococcus aureus infection_Homo sapiens_hsa051501.39220567
27Circadian rhythm_Homo sapiens_hsa047101.37693791
28Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.35009300
29Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.34781537
30Ether lipid metabolism_Homo sapiens_hsa005651.34331198
31Tight junction_Homo sapiens_hsa045301.26609595
32Bladder cancer_Homo sapiens_hsa052191.26588807
33ECM-receptor interaction_Homo sapiens_hsa045121.25302182
34Hippo signaling pathway_Homo sapiens_hsa043901.20101077
35Steroid hormone biosynthesis_Homo sapiens_hsa001401.18989737
36PPAR signaling pathway_Homo sapiens_hsa033201.16497895
37Central carbon metabolism in cancer_Homo sapiens_hsa052301.15417412
38Hedgehog signaling pathway_Homo sapiens_hsa043401.15135558
39Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.12334891
40Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.12144254
41ABC transporters_Homo sapiens_hsa020101.07049817
42Complement and coagulation cascades_Homo sapiens_hsa046101.05937827
43Tryptophan metabolism_Homo sapiens_hsa003801.03950189
44Sulfur metabolism_Homo sapiens_hsa009201.02897891
45Proteoglycans in cancer_Homo sapiens_hsa052051.01461159
46Fatty acid metabolism_Homo sapiens_hsa012120.99259954
47Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.97455567
48Glutathione metabolism_Homo sapiens_hsa004800.94616478
49Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.91759682
50Melanogenesis_Homo sapiens_hsa049160.87777869
51VEGF signaling pathway_Homo sapiens_hsa043700.86715828
52* p53 signaling pathway_Homo sapiens_hsa041150.86664340
53Regulation of actin cytoskeleton_Homo sapiens_hsa048100.85075476
54Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.83438686
55Galactose metabolism_Homo sapiens_hsa000520.82946820
56Pentose and glucuronate interconversions_Homo sapiens_hsa000400.82333687
57Notch signaling pathway_Homo sapiens_hsa043300.81653434
58Axon guidance_Homo sapiens_hsa043600.79567895
59Steroid biosynthesis_Homo sapiens_hsa001000.78353911
60Thyroid cancer_Homo sapiens_hsa052160.77535100
61Arginine biosynthesis_Homo sapiens_hsa002200.77042895
62Pancreatic cancer_Homo sapiens_hsa052120.76302673
63Amoebiasis_Homo sapiens_hsa051460.75608882
64Arginine and proline metabolism_Homo sapiens_hsa003300.75339170
65Mineral absorption_Homo sapiens_hsa049780.75253961
66TGF-beta signaling pathway_Homo sapiens_hsa043500.73037454
67Pathways in cancer_Homo sapiens_hsa052000.72725133
68Choline metabolism in cancer_Homo sapiens_hsa052310.72557429
69ErbB signaling pathway_Homo sapiens_hsa040120.72390137
70Drug metabolism - other enzymes_Homo sapiens_hsa009830.71724790
71Leukocyte transendothelial migration_Homo sapiens_hsa046700.71309398
72Pancreatic secretion_Homo sapiens_hsa049720.70101524
73Fructose and mannose metabolism_Homo sapiens_hsa000510.69700416
74Sphingolipid signaling pathway_Homo sapiens_hsa040710.68577186
75Vitamin digestion and absorption_Homo sapiens_hsa049770.68374930
76Insulin signaling pathway_Homo sapiens_hsa049100.66690616
77Folate biosynthesis_Homo sapiens_hsa007900.66387294
78Glioma_Homo sapiens_hsa052140.65715811
79MicroRNAs in cancer_Homo sapiens_hsa052060.65081862
80Inositol phosphate metabolism_Homo sapiens_hsa005620.65055345
81Phosphatidylinositol signaling system_Homo sapiens_hsa040700.64804341
82Renal cell carcinoma_Homo sapiens_hsa052110.64751478
83Fatty acid biosynthesis_Homo sapiens_hsa000610.63711658
84Thyroid hormone signaling pathway_Homo sapiens_hsa049190.63388297
85Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.63274364
86Vibrio cholerae infection_Homo sapiens_hsa051100.63112525
87PI3K-Akt signaling pathway_Homo sapiens_hsa041510.62763881
88Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.62617221
89Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.62485388
90Hepatitis C_Homo sapiens_hsa051600.61361023
91Chronic myeloid leukemia_Homo sapiens_hsa052200.61115014
92Butanoate metabolism_Homo sapiens_hsa006500.60499391
93Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.60277111
94Endocytosis_Homo sapiens_hsa041440.59932414
95Prostate cancer_Homo sapiens_hsa052150.56658483
96Peroxisome_Homo sapiens_hsa041460.56126867
97Protein digestion and absorption_Homo sapiens_hsa049740.55147699
98Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.54271621
99Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.53243275
100Nitrogen metabolism_Homo sapiens_hsa009100.52136512
101GnRH signaling pathway_Homo sapiens_hsa049120.51403940
102Wnt signaling pathway_Homo sapiens_hsa043100.49815808
103N-Glycan biosynthesis_Homo sapiens_hsa005100.49593287
104Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.46562179
105Bile secretion_Homo sapiens_hsa049760.44588787
106Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.44465695
107Insulin resistance_Homo sapiens_hsa049310.43530951
108Propanoate metabolism_Homo sapiens_hsa006400.41110560
109Small cell lung cancer_Homo sapiens_hsa052220.40691719
110Ovarian steroidogenesis_Homo sapiens_hsa049130.40527908
111Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.40091871
112Melanoma_Homo sapiens_hsa052180.38855785
113Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.38844433
114Glycerophospholipid metabolism_Homo sapiens_hsa005640.38117777
115Adipocytokine signaling pathway_Homo sapiens_hsa049200.37053421
116Toxoplasmosis_Homo sapiens_hsa051450.35732033
117Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.35045082
118Renin secretion_Homo sapiens_hsa049240.34580474
119Ras signaling pathway_Homo sapiens_hsa040140.32984985
120Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.32557603
121Starch and sucrose metabolism_Homo sapiens_hsa005000.29738144
122Jak-STAT signaling pathway_Homo sapiens_hsa046300.28818047
123Endometrial cancer_Homo sapiens_hsa052130.28548728
124Dorso-ventral axis formation_Homo sapiens_hsa043200.28508843
125Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.26939168
126Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.26665905
127Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.26374798
128Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.25226101
129Pertussis_Homo sapiens_hsa051330.24594616
130Focal adhesion_Homo sapiens_hsa045100.23693026
131Rap1 signaling pathway_Homo sapiens_hsa040150.23621873
132Vascular smooth muscle contraction_Homo sapiens_hsa042700.22322035
133Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.21674506

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