Rank | Gene Set | Z-score |
---|---|---|
1 | ribosomal small subunit assembly (GO:0000028) | 6.93435578 |
2 | DNA deamination (GO:0045006) | 6.19918702 |
3 | ribosomal small subunit biogenesis (GO:0042274) | 5.58573598 |
4 | viral transcription (GO:0019083) | 5.13055669 |
5 | translational termination (GO:0006415) | 4.97694757 |
6 | maturation of SSU-rRNA (GO:0030490) | 4.94410992 |
7 | proteasome assembly (GO:0043248) | 4.66145225 |
8 | kinetochore organization (GO:0051383) | 4.63448558 |
9 | telomere maintenance via semi-conservative replication (GO:0032201) | 4.62912481 |
10 | DNA replication initiation (GO:0006270) | 4.55755613 |
11 | kinetochore assembly (GO:0051382) | 4.39511380 |
12 | pseudouridine synthesis (GO:0001522) | 4.29943284 |
13 | translational elongation (GO:0006414) | 4.27550962 |
14 | formation of translation preinitiation complex (GO:0001731) | 4.18328696 |
15 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 4.17107575 |
16 | regulation of mitochondrial translation (GO:0070129) | 4.14236899 |
17 | DNA strand elongation involved in DNA replication (GO:0006271) | 4.14122793 |
18 | respiratory chain complex IV assembly (GO:0008535) | 4.08701151 |
19 | translational initiation (GO:0006413) | 4.08057524 |
20 | ribosomal large subunit biogenesis (GO:0042273) | 4.06821810 |
21 | protein targeting to ER (GO:0045047) | 4.04883363 |
22 | DNA double-strand break processing (GO:0000729) | 4.04280258 |
23 | cotranslational protein targeting to membrane (GO:0006613) | 4.04202834 |
24 | ribosome assembly (GO:0042255) | 4.03739800 |
25 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.02608140 |
26 | chaperone-mediated protein transport (GO:0072321) | 3.99914301 |
27 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.99875432 |
28 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.99411098 |
29 | telomere maintenance via recombination (GO:0000722) | 3.97615917 |
30 | DNA strand elongation (GO:0022616) | 3.90686363 |
31 | meiotic chromosome segregation (GO:0045132) | 3.87829477 |
32 | establishment of integrated proviral latency (GO:0075713) | 3.84367522 |
33 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.83554302 |
34 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.82975115 |
35 | viral life cycle (GO:0019058) | 3.82351593 |
36 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.80021847 |
37 | maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005) | 3.79051068 |
38 | cellular protein complex disassembly (GO:0043624) | 3.78525600 |
39 | rRNA modification (GO:0000154) | 3.76513117 |
40 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.76223020 |
41 | protein localization to endoplasmic reticulum (GO:0070972) | 3.74188424 |
42 | poly(A)+ mRNA export from nucleus (GO:0016973) | 3.70986641 |
43 | mitotic recombination (GO:0006312) | 3.70352137 |
44 | protein complex biogenesis (GO:0070271) | 3.68375271 |
45 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.68276025 |
46 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.64938477 |
47 | telomere maintenance via telomere lengthening (GO:0010833) | 3.63704516 |
48 | purine nucleobase biosynthetic process (GO:0009113) | 3.60458440 |
49 | replication fork processing (GO:0031297) | 3.57857078 |
50 | CENP-A containing nucleosome assembly (GO:0034080) | 3.57695203 |
51 | chromatin remodeling at centromere (GO:0031055) | 3.56842687 |
52 | DNA replication checkpoint (GO:0000076) | 3.56122131 |
53 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.54517477 |
54 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.54371692 |
55 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.51594728 |
56 | termination of RNA polymerase III transcription (GO:0006386) | 3.51594728 |
57 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.51281253 |
58 | DNA catabolic process, exonucleolytic (GO:0000738) | 3.50835482 |
59 | GDP-mannose metabolic process (GO:0019673) | 3.50477400 |
60 | cytochrome complex assembly (GO:0017004) | 3.48980374 |
61 | regulation of helicase activity (GO:0051095) | 3.48889840 |
62 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 3.48511607 |
63 | spliceosomal snRNP assembly (GO:0000387) | 3.48393815 |
64 | nucleotide-excision repair, DNA gap filling (GO:0006297) | 3.46897223 |
65 | cullin deneddylation (GO:0010388) | 3.46677012 |
66 | negative regulation of ligase activity (GO:0051352) | 3.44498352 |
67 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.44498352 |
68 | protein complex disassembly (GO:0043241) | 3.43843711 |
69 | ribosome biogenesis (GO:0042254) | 3.41998839 |
70 | regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083) | 3.41554582 |
71 | regulation of nuclear cell cycle DNA replication (GO:0033262) | 3.40231945 |
72 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.39599874 |
73 | NADH dehydrogenase complex assembly (GO:0010257) | 3.39599874 |
74 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.39599874 |
75 | rRNA processing (GO:0006364) | 3.36776198 |
76 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.34021753 |
77 | rRNA methylation (GO:0031167) | 3.31843036 |
78 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.31769822 |
79 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.31769822 |
80 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.31769822 |
81 | macromolecular complex disassembly (GO:0032984) | 3.30045929 |
82 | ATP synthesis coupled proton transport (GO:0015986) | 3.29879821 |
83 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.29879821 |
84 | rRNA metabolic process (GO:0016072) | 3.29541343 |
85 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.28628636 |
86 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.28628636 |
87 | protein targeting to mitochondrion (GO:0006626) | 3.28015653 |
88 | protein deneddylation (GO:0000338) | 3.27227427 |
89 | proline biosynthetic process (GO:0006561) | 3.24961204 |
90 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.22381261 |
91 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.22381261 |
92 | regulation of attachment of spindle microtubules to kinetochore (GO:0051988) | 3.20859262 |
93 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.20519244 |
94 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.20519244 |
95 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 3.19615055 |
96 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.18103936 |
97 | translation (GO:0006412) | 3.17412605 |
98 | nucleobase biosynthetic process (GO:0046112) | 3.17306214 |
99 | IMP metabolic process (GO:0046040) | 3.15747679 |
100 | negative regulation of mRNA splicing, via spliceosome (GO:0048025) | 3.15374557 |
101 | oxidative phosphorylation (GO:0006119) | 3.15102250 |
102 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 3.14837109 |
103 | negative regulation of transcription by competitive promoter binding (GO:0010944) | 3.14749226 |
104 | respiratory electron transport chain (GO:0022904) | 3.13761290 |
105 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 3.13366780 |
106 | DNA unwinding involved in DNA replication (GO:0006268) | 3.11749502 |
107 | establishment of viral latency (GO:0019043) | 3.11298765 |
108 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 3.08500612 |
109 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 3.08500612 |
110 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 3.06833267 |
111 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 3.06513944 |
112 | protein neddylation (GO:0045116) | 3.06351209 |
113 | protein localization to kinetochore (GO:0034501) | 3.05825201 |
114 | establishment of protein localization to mitochondrion (GO:0072655) | 3.05171515 |
115 | positive regulation of ligase activity (GO:0051351) | 3.04688562 |
116 | electron transport chain (GO:0022900) | 3.04590859 |
117 | DNA damage response, detection of DNA damage (GO:0042769) | 3.03428410 |
118 | IMP biosynthetic process (GO:0006188) | 3.02868179 |
119 | transcription from mitochondrial promoter (GO:0006390) | 3.01277871 |
120 | protein localization to mitochondrion (GO:0070585) | 3.00062307 |
121 | mRNA catabolic process (GO:0006402) | 2.99803535 |
122 | negative regulation of RNA splicing (GO:0033119) | 2.98703269 |
123 | DNA replication-dependent nucleosome assembly (GO:0006335) | 2.97880091 |
124 | DNA replication-dependent nucleosome organization (GO:0034723) | 2.97880091 |
125 | 7-methylguanosine mRNA capping (GO:0006370) | 2.96615243 |
126 | cellular component biogenesis (GO:0044085) | 2.96370663 |
127 | histone exchange (GO:0043486) | 2.96094558 |
128 | RNA catabolic process (GO:0006401) | 2.95411047 |
129 | double-strand break repair via nonhomologous end joining (GO:0006303) | 2.95179486 |
130 | non-recombinational repair (GO:0000726) | 2.95179486 |
131 | tRNA aminoacylation (GO:0043039) | 2.94686411 |
132 | amino acid activation (GO:0043038) | 2.94686411 |
133 | tRNA aminoacylation for protein translation (GO:0006418) | 2.91880021 |
134 | DNA ligation (GO:0006266) | 2.91800895 |
135 | DNA synthesis involved in DNA repair (GO:0000731) | 2.89045946 |
136 | protein localization to chromosome, centromeric region (GO:0071459) | 2.88852598 |
137 | 7-methylguanosine RNA capping (GO:0009452) | 2.88176040 |
138 | RNA capping (GO:0036260) | 2.88176040 |
139 | dolichol-linked oligosaccharide biosynthetic process (GO:0006488) | 2.88147306 |
140 | regulation of ubiquitin-protein transferase activity (GO:0051438) | 2.88024848 |
141 | regulation of mitotic spindle checkpoint (GO:1903504) | 2.86855073 |
142 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 2.86855073 |
143 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 2.86445042 |
144 | intra-S DNA damage checkpoint (GO:0031573) | 2.84785564 |
145 | regulation of double-strand break repair via homologous recombination (GO:0010569) | 2.84645266 |
146 | mitotic metaphase plate congression (GO:0007080) | 2.83604096 |
147 | nucleobase-containing small molecule interconversion (GO:0015949) | 2.83130832 |
148 | termination of RNA polymerase II transcription (GO:0006369) | 2.82586938 |
149 | protein-cofactor linkage (GO:0018065) | 2.82032601 |
150 | metallo-sulfur cluster assembly (GO:0031163) | 2.82019052 |
151 | iron-sulfur cluster assembly (GO:0016226) | 2.82019052 |
152 | histone H4-K12 acetylation (GO:0043983) | 2.81532817 |
153 | DNA replication-independent nucleosome assembly (GO:0006336) | 2.80085419 |
154 | DNA replication-independent nucleosome organization (GO:0034724) | 2.80085419 |
155 | pyrimidine nucleotide catabolic process (GO:0006244) | 2.78072468 |
156 | transcription-coupled nucleotide-excision repair (GO:0006283) | 2.77545928 |
157 | somatic recombination of immunoglobulin gene segments (GO:0016447) | 2.76721636 |
158 | RNA methylation (GO:0001510) | 2.74925840 |
159 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 2.74183475 |
160 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 2.74183475 |
161 | isotype switching (GO:0045190) | 2.74183475 |
162 | definitive hemopoiesis (GO:0060216) | 2.73410444 |
163 | negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665) | 2.73051719 |
164 | nuclear pore complex assembly (GO:0051292) | 2.72024870 |
165 | base-excision repair (GO:0006284) | 2.72001849 |
166 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 2.71873143 |
167 | resolution of meiotic recombination intermediates (GO:0000712) | 2.70584670 |
168 | negative regulation of mRNA processing (GO:0050686) | 2.69915670 |
169 | viral mRNA export from host cell nucleus (GO:0046784) | 2.67557512 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 8.48216943 |
2 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 4.71597614 |
3 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 3.48549968 |
4 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 3.30117879 |
5 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 3.28540592 |
6 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 3.28100000 |
7 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 3.15874545 |
8 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 3.04992227 |
9 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.96076934 |
10 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.92054178 |
11 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.85855158 |
12 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.83805553 |
13 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.70453198 |
14 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.68486484 |
15 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.46245432 |
16 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.40693616 |
17 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 2.36350625 |
18 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 2.22078360 |
19 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 2.19607309 |
20 | * VDR_23849224_ChIP-Seq_CD4+_Human | 2.14396886 |
21 | XRN2_22483619_ChIP-Seq_HELA_Human | 2.08697595 |
22 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.99156197 |
23 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.95550396 |
24 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.94113359 |
25 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.92580504 |
26 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.90565228 |
27 | * TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.89479289 |
28 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.88811229 |
29 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.87161048 |
30 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.87146417 |
31 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.86208356 |
32 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.85530204 |
33 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.84830361 |
34 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.83033690 |
35 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.82526557 |
36 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.76835862 |
37 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.76229308 |
38 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.75951850 |
39 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.74742636 |
40 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.73952281 |
41 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.71080441 |
42 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.69283484 |
43 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.68974747 |
44 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.68691723 |
45 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.68539101 |
46 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.64744252 |
47 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.63056138 |
48 | MYC_22102868_ChIP-Seq_BL_Human | 1.62836563 |
49 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.62382121 |
50 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.60970565 |
51 | * SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.60592820 |
52 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.59616900 |
53 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.54309166 |
54 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.53711720 |
55 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.53691887 |
56 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.52519615 |
57 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.49424219 |
58 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.44812876 |
59 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 1.41366682 |
60 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.39943082 |
61 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.39889754 |
62 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.37163150 |
63 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 1.36810983 |
64 | * FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.36789103 |
65 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.35535963 |
66 | * ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.35020590 |
67 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.34251750 |
68 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.32035019 |
69 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.31510549 |
70 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.31445666 |
71 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.30014075 |
72 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.30001714 |
73 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.28006697 |
74 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.27084607 |
75 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.26144812 |
76 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.24242157 |
77 | VDR_22108803_ChIP-Seq_LS180_Human | 1.22306066 |
78 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 1.21745265 |
79 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 1.21745265 |
80 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 1.21745265 |
81 | EWS_26573619_Chip-Seq_HEK293_Human | 1.20864875 |
82 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.18428694 |
83 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.17909699 |
84 | NANOG_18358816_ChIP-ChIP_MESCs_Mouse | 1.16648687 |
85 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.15999109 |
86 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.15276198 |
87 | FUS_26573619_Chip-Seq_HEK293_Human | 1.15104548 |
88 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.14704606 |
89 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.14100148 |
90 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 1.13209104 |
91 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.12153606 |
92 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.09538946 |
93 | * GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 1.08012810 |
94 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.07135806 |
95 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 1.05669668 |
96 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.04487211 |
97 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.01869577 |
98 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.01179639 |
99 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.00240741 |
100 | NACC1_18358816_ChIP-ChIP_MESCs_Mouse | 0.98655573 |
101 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.98560344 |
102 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 0.96807417 |
103 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 0.95831542 |
104 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 0.95691201 |
105 | STAT1_20625510_ChIP-Seq_HELA_Human | 0.94518441 |
106 | * TFEB_21752829_ChIP-Seq_HELA_Human | 0.94089776 |
107 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 0.93522026 |
108 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 0.92905248 |
109 | VDR_24763502_ChIP-Seq_THP-1_Human | 0.92688595 |
110 | SOX17_20123909_ChIP-Seq_XEN_Mouse | 0.91845228 |
111 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 0.91749251 |
112 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 0.90957948 |
113 | CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.90911372 |
114 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 0.89847699 |
115 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 0.87925969 |
116 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 0.87629490 |
117 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 0.87447560 |
118 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 0.87350614 |
119 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 0.84843594 |
120 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.84677005 |
121 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 0.79701667 |
122 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.73389397 |
123 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 0.73314384 |
124 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 0.72994569 |
125 | TP53_22573176_ChIP-Seq_HFKS_Human | 0.72969323 |
126 | TAF15_26573619_Chip-Seq_HEK293_Human | 0.72517478 |
127 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.69994732 |
128 | TBX5_21415370_ChIP-Seq_HL-1_Mouse | 0.69244254 |
129 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.69042110 |
130 | AR_20517297_ChIP-Seq_VCAP_Human | 0.68241853 |
131 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 0.66989232 |
132 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 0.66360939 |
133 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.66345685 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0008057_abnormal_DNA_replication | 5.18120199 |
2 | MP0003693_abnormal_embryo_hatching | 5.02116341 |
3 | MP0009379_abnormal_foot_pigmentation | 3.65883290 |
4 | MP0010094_abnormal_chromosome_stability | 3.61418978 |
5 | MP0003111_abnormal_nucleus_morphology | 3.58930029 |
6 | MP0005174_abnormal_tail_pigmentation | 3.43623814 |
7 | MP0003077_abnormal_cell_cycle | 3.16447417 |
8 | MP0004957_abnormal_blastocyst_morpholog | 3.06021434 |
9 | MP0008058_abnormal_DNA_repair | 3.03874680 |
10 | MP0000372_irregular_coat_pigmentation | 2.96990287 |
11 | MP0000490_abnormal_crypts_of | 2.81502998 |
12 | MP0006292_abnormal_olfactory_placode | 2.68129660 |
13 | MP0002396_abnormal_hematopoietic_system | 2.62395544 |
14 | MP0000015_abnormal_ear_pigmentation | 2.36040974 |
15 | MP0008007_abnormal_cellular_replicative | 2.15263784 |
16 | MP0006035_abnormal_mitochondrial_morpho | 2.11294038 |
17 | MP0005075_abnormal_melanosome_morpholog | 2.08514338 |
18 | MP0005408_hypopigmentation | 2.01444544 |
19 | MP0002277_abnormal_respiratory_mucosa | 1.95602879 |
20 | MP0003567_abnormal_fetal_cardiomyocyte | 1.91733530 |
21 | MP0005397_hematopoietic_system_phenotyp | 1.87812223 |
22 | MP0001545_abnormal_hematopoietic_system | 1.87812223 |
23 | MP0002938_white_spotting | 1.79966024 |
24 | MP0001764_abnormal_homeostasis | 1.79225403 |
25 | MP0002095_abnormal_skin_pigmentation | 1.78556011 |
26 | MP0002102_abnormal_ear_morphology | 1.76673830 |
27 | MP0008932_abnormal_embryonic_tissue | 1.65579777 |
28 | MP0006072_abnormal_retinal_apoptosis | 1.64018942 |
29 | MP0001188_hyperpigmentation | 1.63840581 |
30 | MP0003123_paternal_imprinting | 1.63455525 |
31 | MP0003121_genomic_imprinting | 1.62143524 |
32 | MP0001348_abnormal_lacrimal_gland | 1.58107108 |
33 | MP0001984_abnormal_olfaction | 1.56972389 |
34 | MP0009697_abnormal_copulation | 1.54596252 |
35 | MP0009278_abnormal_bone_marrow | 1.54180519 |
36 | MP0008877_abnormal_DNA_methylation | 1.50891955 |
37 | MP0004147_increased_porphyrin_level | 1.48127560 |
38 | MP0003786_premature_aging | 1.46996517 |
39 | MP0003941_abnormal_skin_development | 1.46791611 |
40 | MP0000350_abnormal_cell_proliferation | 1.46540726 |
41 | MP0000313_abnormal_cell_death | 1.44852795 |
42 | MP0002090_abnormal_vision | 1.41088353 |
43 | MP0008789_abnormal_olfactory_epithelium | 1.40292906 |
44 | MP0005409_darkened_coat_color | 1.39708342 |
45 | MP0001529_abnormal_vocalization | 1.39220347 |
46 | MP0003806_abnormal_nucleotide_metabolis | 1.36376836 |
47 | MP0001293_anophthalmia | 1.35770407 |
48 | MP0004808_abnormal_hematopoietic_stem | 1.35422447 |
49 | MP0003186_abnormal_redox_activity | 1.33756311 |
50 | MP0003763_abnormal_thymus_physiology | 1.33521260 |
51 | MP0002138_abnormal_hepatobiliary_system | 1.33344230 |
52 | MP0003122_maternal_imprinting | 1.32627639 |
53 | MP0005253_abnormal_eye_physiology | 1.27585000 |
54 | MP0000465_gastrointestinal_hemorrhage | 1.27146091 |
55 | MP0000358_abnormal_cell_content/ | 1.21872307 |
56 | MP0002398_abnormal_bone_marrow | 1.21453533 |
57 | MP0005084_abnormal_gallbladder_morpholo | 1.20040348 |
58 | MP0002019_abnormal_tumor_incidence | 1.19993298 |
59 | MP0005332_abnormal_amino_acid | 1.19721153 |
60 | MP0005379_endocrine/exocrine_gland_phen | 1.19414725 |
61 | MP0002163_abnormal_gland_morphology | 1.18570847 |
62 | MP0002210_abnormal_sex_determination | 1.18266922 |
63 | MP0003315_abnormal_perineum_morphology | 1.17262693 |
64 | MP0002254_reproductive_system_inflammat | 1.17109582 |
65 | MP0002736_abnormal_nociception_after | 1.16439177 |
66 | MP0005551_abnormal_eye_electrophysiolog | 1.13825857 |
67 | MP0001730_embryonic_growth_arrest | 1.11786372 |
68 | MP0003787_abnormal_imprinting | 1.11558685 |
69 | MP0005464_abnormal_platelet_physiology | 1.09850832 |
70 | MP0001835_abnormal_antigen_presentation | 1.08805956 |
71 | MP0003195_calcinosis | 1.08360865 |
72 | MP0002638_abnormal_pupillary_reflex | 1.07474961 |
73 | MP0000703_abnormal_thymus_morphology | 1.06540869 |
74 | MP0000689_abnormal_spleen_morphology | 1.05739200 |
75 | MP0009333_abnormal_splenocyte_physiolog | 1.04041910 |
76 | MP0006036_abnormal_mitochondrial_physio | 1.03413013 |
77 | MP0001986_abnormal_taste_sensitivity | 1.02902194 |
78 | MP0001119_abnormal_female_reproductive | 1.02187136 |
79 | MP0000678_abnormal_parathyroid_gland | 1.00733769 |
80 | MP0002160_abnormal_reproductive_system | 1.00394414 |
81 | MP0002722_abnormal_immune_system | 1.00175103 |
82 | MP0008995_early_reproductive_senescence | 0.99536870 |
83 | MP0000647_abnormal_sebaceous_gland | 0.99169113 |
84 | MP0002132_abnormal_respiratory_system | 0.98864284 |
85 | MP0005220_abnormal_exocrine_pancreas | 0.98187955 |
86 | MP0005025_abnormal_response_to | 0.97488949 |
87 | MP0003436_decreased_susceptibility_to | 0.96431256 |
88 | MP0001145_abnormal_male_reproductive | 0.96062319 |
89 | MP0002075_abnormal_coat/hair_pigmentati | 0.95909023 |
90 | MP0005380_embryogenesis_phenotype | 0.95621351 |
91 | MP0001672_abnormal_embryogenesis/_devel | 0.95621351 |
92 | MP0000470_abnormal_stomach_morphology | 0.94901321 |
93 | MP0003183_abnormal_peptide_metabolism | 0.94500142 |
94 | MP0002452_abnormal_antigen_presenting | 0.93002575 |
95 | MP0003718_maternal_effect | 0.92651417 |
96 | MP0010352_gastrointestinal_tract_polyps | 0.92202695 |
97 | MP0001324_abnormal_eye_pigmentation | 0.91809492 |
98 | MP0002429_abnormal_blood_cell | 0.91365232 |
99 | MP0002837_dystrophic_cardiac_calcinosis | 0.90926807 |
100 | MP0001666_abnormal_nutrient_absorption | 0.90923740 |
101 | MP0000716_abnormal_immune_system | 0.89136667 |
102 | MP0010155_abnormal_intestine_physiology | 0.89123530 |
103 | MP0001800_abnormal_humoral_immune | 0.88875242 |
104 | MP0003119_abnormal_digestive_system | 0.88584315 |
105 | MP0002148_abnormal_hypersensitivity_rea | 0.88446703 |
106 | MP0005394_taste/olfaction_phenotype | 0.88041914 |
107 | MP0005499_abnormal_olfactory_system | 0.88041914 |
108 | MP0005451_abnormal_body_composition | 0.87099898 |
109 | MP0000477_abnormal_intestine_morphology | 0.87072591 |
110 | MP0003937_abnormal_limbs/digits/tail_de | 0.86359400 |
111 | MP0005645_abnormal_hypothalamus_physiol | 0.85977990 |
112 | MP0001697_abnormal_embryo_size | 0.85927070 |
113 | MP0002233_abnormal_nose_morphology | 0.85253133 |
114 | MP0009046_muscle_twitch | 0.85108228 |
115 | MP0002723_abnormal_immune_serum | 0.83390523 |
116 | MP0003136_yellow_coat_color | 0.82904352 |
117 | MP0003828_pulmonary_edema | 0.81553095 |
118 | MP0010386_abnormal_urinary_bladder | 0.81124542 |
119 | MP0001186_pigmentation_phenotype | 0.80779856 |
120 | MP0003646_muscle_fatigue | 0.79855296 |
121 | MP0001727_abnormal_embryo_implantation | 0.79541108 |
122 | MP0003880_abnormal_central_pattern | 0.79372772 |
123 | MP0002080_prenatal_lethality | 0.79243979 |
124 | MP0002420_abnormal_adaptive_immunity | 0.79222723 |
125 | MP0002086_abnormal_extraembryonic_tissu | 0.78859948 |
126 | MP0003011_delayed_dark_adaptation | 0.78813892 |
127 | MP0000653_abnormal_sex_gland | 0.78695350 |
128 | MP0003984_embryonic_growth_retardation | 0.78011106 |
129 | MP0002085_abnormal_embryonic_tissue | 0.77857635 |
130 | MP0001819_abnormal_immune_cell | 0.77779854 |
131 | MP0005389_reproductive_system_phenotype | 0.77053677 |
132 | MP0009672_abnormal_birth_weight | 0.77028072 |
133 | MP0002249_abnormal_larynx_morphology | 0.76980775 |
134 | MP0002084_abnormal_developmental_patter | 0.76877406 |
135 | MP0005367_renal/urinary_system_phenotyp | 0.76778862 |
136 | MP0000516_abnormal_urinary_system | 0.76778862 |
137 | MP0008875_abnormal_xenobiotic_pharmacok | 0.76764960 |
138 | MP0001929_abnormal_gametogenesis | 0.76486110 |
139 | MP0002928_abnormal_bile_duct | 0.75316644 |
140 | MP0004133_heterotaxia | 0.75258516 |
141 | MP0001919_abnormal_reproductive_system | 0.75245899 |
142 | MP0003698_abnormal_male_reproductive | 0.75047892 |
143 | MP0002405_respiratory_system_inflammati | 0.74713290 |
144 | MP0002088_abnormal_embryonic_growth/wei | 0.74258013 |
145 | MP0003890_abnormal_embryonic-extraembry | 0.74037564 |
146 | MP0010234_abnormal_vibrissa_follicle | 0.73014179 |
147 | MP0002751_abnormal_autonomic_nervous | 0.71643537 |
148 | MP0000685_abnormal_immune_system | 0.71592757 |
149 | MP0006054_spinal_hemorrhage | 0.71269712 |
150 | MP0000681_abnormal_thyroid_gland | 0.69876972 |
151 | MP0000858_altered_metastatic_potential | 0.68627420 |
152 | MP0001485_abnormal_pinna_reflex | 0.67607557 |
153 | MP0005636_abnormal_mineral_homeostasis | 0.65804220 |
154 | MP0004215_abnormal_myocardial_fiber | 0.63790861 |
155 | MP0003137_abnormal_impulse_conducting | 0.62006084 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Birth length less than 3rd percentile (HP:0003561) | 5.33479345 |
2 | Reticulocytopenia (HP:0001896) | 5.18814260 |
3 | Acute necrotizing encephalopathy (HP:0006965) | 4.50106116 |
4 | Acute encephalopathy (HP:0006846) | 4.37518222 |
5 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.23785137 |
6 | Chromsome breakage (HP:0040012) | 4.14399412 |
7 | Breast hypoplasia (HP:0003187) | 4.13339553 |
8 | Mitochondrial inheritance (HP:0001427) | 3.95979475 |
9 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 3.92985573 |
10 | Increased CSF lactate (HP:0002490) | 3.92584794 |
11 | Pustule (HP:0200039) | 3.83712235 |
12 | Abnormality of cells of the erythroid lineage (HP:0012130) | 3.82146025 |
13 | Progressive macrocephaly (HP:0004481) | 3.72712505 |
14 | Hyperglycinemia (HP:0002154) | 3.72039336 |
15 | Aplastic anemia (HP:0001915) | 3.64917816 |
16 | Abnormal number of erythroid precursors (HP:0012131) | 3.60488308 |
17 | Hepatocellular necrosis (HP:0001404) | 3.58409700 |
18 | Reduced antithrombin III activity (HP:0001976) | 3.49616150 |
19 | Pallor (HP:0000980) | 3.48778693 |
20 | Thrombocytosis (HP:0001894) | 3.37136137 |
21 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 3.36056661 |
22 | Aplasia cutis congenita (HP:0001057) | 3.34613706 |
23 | Hepatic necrosis (HP:0002605) | 3.32648566 |
24 | Type I transferrin isoform profile (HP:0003642) | 3.29449429 |
25 | Cerebral edema (HP:0002181) | 3.28519684 |
26 | Macrocytic anemia (HP:0001972) | 3.26568798 |
27 | IgM deficiency (HP:0002850) | 3.20357886 |
28 | Abnormality of the preputium (HP:0100587) | 3.18940220 |
29 | Increased intramyocellular lipid droplets (HP:0012240) | 3.12819179 |
30 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 3.11770610 |
31 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 3.11770610 |
32 | Poikiloderma (HP:0001029) | 3.11673991 |
33 | Increased serum pyruvate (HP:0003542) | 3.09780430 |
34 | Cheilitis (HP:0100825) | 3.00377175 |
35 | Increased serum lactate (HP:0002151) | 2.95814657 |
36 | Agnosia (HP:0010524) | 2.95411968 |
37 | Petechiae (HP:0000967) | 2.95072200 |
38 | Lactic acidosis (HP:0003128) | 2.94834624 |
39 | Cerebral hypomyelination (HP:0006808) | 2.91603544 |
40 | Abnormality of glycolysis (HP:0004366) | 2.84469401 |
41 | Meckel diverticulum (HP:0002245) | 2.82928931 |
42 | Absent thumb (HP:0009777) | 2.80488735 |
43 | Abnormality of the ileum (HP:0001549) | 2.79987411 |
44 | Methylmalonic acidemia (HP:0002912) | 2.74187689 |
45 | Asplenia (HP:0001746) | 2.73786565 |
46 | Breech presentation (HP:0001623) | 2.73463657 |
47 | Abnormality of methionine metabolism (HP:0010901) | 2.71048154 |
48 | Hypochromic anemia (HP:0001931) | 2.69479825 |
49 | Exercise intolerance (HP:0003546) | 2.68314281 |
50 | Hyperglycinuria (HP:0003108) | 2.67681654 |
51 | Abnormality of serum amino acid levels (HP:0003112) | 2.64768501 |
52 | Microvesicular hepatic steatosis (HP:0001414) | 2.64211774 |
53 | Lethargy (HP:0001254) | 2.62411788 |
54 | Multiple enchondromatosis (HP:0005701) | 2.59424758 |
55 | Abnormality of glycine metabolism (HP:0010895) | 2.56056762 |
56 | Abnormality of serine family amino acid metabolism (HP:0010894) | 2.56056762 |
57 | Trismus (HP:0000211) | 2.55246109 |
58 | Exertional dyspnea (HP:0002875) | 2.53549600 |
59 | Premature graying of hair (HP:0002216) | 2.51484394 |
60 | Methylmalonic aciduria (HP:0012120) | 2.50886681 |
61 | Increased muscle lipid content (HP:0009058) | 2.50186654 |
62 | Prolonged bleeding time (HP:0003010) | 2.49648396 |
63 | Colon cancer (HP:0003003) | 2.49177931 |
64 | Gastrointestinal inflammation (HP:0004386) | 2.47914411 |
65 | 3-Methylglutaconic aciduria (HP:0003535) | 2.46287432 |
66 | Myelodysplasia (HP:0002863) | 2.45367814 |
67 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.45233002 |
68 | Inflammation of the large intestine (HP:0002037) | 2.45228011 |
69 | Progressive inability to walk (HP:0002505) | 2.44306677 |
70 | Basal cell carcinoma (HP:0002671) | 2.42513143 |
71 | Leukodystrophy (HP:0002415) | 2.42198311 |
72 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.40405533 |
73 | Prostate neoplasm (HP:0100787) | 2.40056451 |
74 | Respiratory failure (HP:0002878) | 2.38963895 |
75 | Oral leukoplakia (HP:0002745) | 2.38615733 |
76 | Abnormality of the renal collecting system (HP:0004742) | 2.38442423 |
77 | Abnormality of the labia minora (HP:0012880) | 2.37912457 |
78 | Absent radius (HP:0003974) | 2.33959540 |
79 | Increased hepatocellular lipid droplets (HP:0006565) | 2.32707220 |
80 | Duplicated collecting system (HP:0000081) | 2.32096760 |
81 | Triphalangeal thumb (HP:0001199) | 2.31521769 |
82 | Patellar aplasia (HP:0006443) | 2.31268609 |
83 | Abnormality of chromosome stability (HP:0003220) | 2.31112675 |
84 | Bone marrow hypocellularity (HP:0005528) | 2.27413716 |
85 | CNS demyelination (HP:0007305) | 2.27394905 |
86 | Clubbing of toes (HP:0100760) | 2.23228692 |
87 | Pancytopenia (HP:0001876) | 2.19903824 |
88 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 2.19224639 |
89 | Selective tooth agenesis (HP:0001592) | 2.17998994 |
90 | CNS hypomyelination (HP:0003429) | 2.16541218 |
91 | Respiratory difficulties (HP:0002880) | 2.15235234 |
92 | Abnormality of alanine metabolism (HP:0010916) | 2.12599361 |
93 | Hyperalaninemia (HP:0003348) | 2.12599361 |
94 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.12599361 |
95 | Pulmonary fibrosis (HP:0002206) | 2.12315583 |
96 | Abnormality of renal resorption (HP:0011038) | 2.11878255 |
97 | Absent forearm bone (HP:0003953) | 2.11057780 |
98 | Aplasia involving forearm bones (HP:0009822) | 2.11057780 |
99 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.10858495 |
100 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.10103049 |
101 | Optic disc pallor (HP:0000543) | 2.07331795 |
102 | Supernumerary spleens (HP:0009799) | 2.06429870 |
103 | Lipid accumulation in hepatocytes (HP:0006561) | 2.06381408 |
104 | Gingival bleeding (HP:0000225) | 2.04695916 |
105 | Aplasia/Hypoplasia of the patella (HP:0006498) | 2.04653081 |
106 | Hypoplasia of the radius (HP:0002984) | 2.03812708 |
107 | Septo-optic dysplasia (HP:0100842) | 2.03543833 |
108 | Premature loss of primary teeth (HP:0006323) | 2.02396577 |
109 | Horseshoe kidney (HP:0000085) | 2.01958530 |
110 | Abnormal protein glycosylation (HP:0012346) | 2.01272052 |
111 | Abnormal glycosylation (HP:0012345) | 2.01272052 |
112 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.01272052 |
113 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.01272052 |
114 | Medial flaring of the eyebrow (HP:0010747) | 2.00561929 |
115 | Hyperinsulinemic hypoglycemia (HP:0000825) | 1.99565197 |
116 | Small intestinal stenosis (HP:0012848) | 1.98199541 |
117 | Duodenal stenosis (HP:0100867) | 1.98199541 |
118 | Pancreatic islet-cell hyperplasia (HP:0004510) | 1.97996998 |
119 | Lip pit (HP:0100267) | 1.97293198 |
120 | Abnormality of vitamin B metabolism (HP:0004340) | 1.96115099 |
121 | Tracheoesophageal fistula (HP:0002575) | 1.95071069 |
122 | Abnormal respiratory epithelium morphology (HP:0012253) | 1.93882919 |
123 | Abnormal respiratory motile cilium morphology (HP:0005938) | 1.93882919 |
124 | Abnormal spermatogenesis (HP:0008669) | 1.93739302 |
125 | Neoplasm of the adrenal gland (HP:0100631) | 1.92918894 |
126 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 1.92617001 |
127 | Renal Fanconi syndrome (HP:0001994) | 1.92591240 |
128 | Slender long bone (HP:0003100) | 1.91040060 |
129 | Acute lymphatic leukemia (HP:0006721) | 1.90256645 |
130 | Abnormality of the anterior horn cell (HP:0006802) | 1.89883445 |
131 | Degeneration of anterior horn cells (HP:0002398) | 1.89883445 |
132 | Hypoglycemic coma (HP:0001325) | 1.89355189 |
133 | Spontaneous hematomas (HP:0007420) | 1.88153777 |
134 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 1.86780619 |
135 | Dicarboxylic aciduria (HP:0003215) | 1.86780619 |
136 | 11 pairs of ribs (HP:0000878) | 1.85782425 |
137 | Tongue fasciculations (HP:0001308) | 1.85367440 |
138 | Hypoglycemic seizures (HP:0002173) | 1.84070392 |
139 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 1.83645466 |
140 | Absent/shortened dynein arms (HP:0200106) | 1.83645466 |
141 | Glycosuria (HP:0003076) | 1.82516289 |
142 | Abnormality of urine glucose concentration (HP:0011016) | 1.82516289 |
143 | Renal cortical cysts (HP:0000803) | 1.82469837 |
144 | Nephrogenic diabetes insipidus (HP:0009806) | 1.81244919 |
145 | Carpal bone hypoplasia (HP:0001498) | 1.80834572 |
146 | Microretrognathia (HP:0000308) | 1.80312598 |
147 | Azoospermia (HP:0000027) | 1.78252217 |
148 | Abnormal lung lobation (HP:0002101) | 1.77798198 |
149 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 1.76927408 |
150 | Abnormality of the duodenum (HP:0002246) | 1.76806035 |
151 | Ependymoma (HP:0002888) | 1.76248005 |
152 | Microcytic anemia (HP:0001935) | 1.76073697 |
153 | Severe visual impairment (HP:0001141) | 1.75758892 |
154 | Rhabdomyosarcoma (HP:0002859) | 1.75660455 |
155 | Abnormal hemoglobin (HP:0011902) | 1.75558940 |
156 | Postnatal microcephaly (HP:0005484) | 1.75324343 |
157 | Microtia (HP:0008551) | 1.74796446 |
158 | Congenital primary aphakia (HP:0007707) | 1.73749313 |
159 | Cleft eyelid (HP:0000625) | 1.73713652 |
160 | Volvulus (HP:0002580) | 1.72886347 |
161 | Megaloblastic anemia (HP:0001889) | 1.72682406 |
162 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.71607899 |
163 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 1.70710131 |
164 | Obstructive lung disease (HP:0006536) | 1.70530640 |
165 | Chronic obstructive pulmonary disease (HP:0006510) | 1.70530640 |
166 | Rectal fistula (HP:0100590) | 1.70389322 |
167 | Rectovaginal fistula (HP:0000143) | 1.70389322 |
168 | X-linked dominant inheritance (HP:0001423) | 1.69639814 |
169 | Recurrent abscess formation (HP:0002722) | 1.69505694 |
170 | Abnormality of the nasal septum (HP:0000419) | 1.68690091 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TRIM28 | 3.33262894 |
2 | NEK1 | 2.91019992 |
3 | CDC7 | 2.86727646 |
4 | BRD4 | 2.85365965 |
5 | MKNK2 | 2.85283314 |
6 | DYRK3 | 2.84694735 |
7 | VRK2 | 2.83902562 |
8 | PLK3 | 2.54871849 |
9 | WEE1 | 2.27788521 |
10 | CDK12 | 2.27560659 |
11 | BUB1 | 2.25627539 |
12 | NME2 | 2.18174563 |
13 | SRPK1 | 2.11842299 |
14 | MAP3K10 | 2.07590340 |
15 | BLK | 2.05810048 |
16 | TSSK6 | 2.03514675 |
17 | PASK | 2.02497873 |
18 | MKNK1 | 1.94141062 |
19 | YES1 | 1.93616543 |
20 | CDK7 | 1.90022129 |
21 | NEK2 | 1.80826840 |
22 | MAP4K2 | 1.79794708 |
23 | PLK1 | 1.78348815 |
24 | VRK1 | 1.78095757 |
25 | TTK | 1.76213397 |
26 | IRAK3 | 1.74344759 |
27 | WNK3 | 1.71345083 |
28 | PIM2 | 1.71092206 |
29 | ACVR1B | 1.60935304 |
30 | PDK2 | 1.59441405 |
31 | TAOK2 | 1.54191081 |
32 | TNK2 | 1.52781547 |
33 | TAOK3 | 1.49064073 |
34 | PLK4 | 1.48806579 |
35 | RPS6KB2 | 1.48609362 |
36 | BMPR1B | 1.46590585 |
37 | TLK1 | 1.46382852 |
38 | TESK2 | 1.45370272 |
39 | AURKB | 1.44459919 |
40 | PRPF4B | 1.37659411 |
41 | IRAK4 | 1.37550807 |
42 | CDK6 | 1.34112711 |
43 | NME1 | 1.33867060 |
44 | MAP3K11 | 1.28290314 |
45 | SCYL2 | 1.26444777 |
46 | TAF1 | 1.23684754 |
47 | CHEK2 | 1.20688306 |
48 | BCR | 1.20496743 |
49 | PAK4 | 1.15988627 |
50 | AURKA | 1.15403025 |
51 | CDK4 | 1.12085139 |
52 | ERBB3 | 1.09848252 |
53 | STK4 | 1.09541851 |
54 | CSF1R | 1.07279021 |
55 | BMX | 1.06916387 |
56 | ATR | 1.06298013 |
57 | MAPK15 | 1.04454227 |
58 | BTK | 1.03660674 |
59 | EEF2K | 1.03485345 |
60 | CCNB1 | 1.02911952 |
61 | CSNK1G3 | 1.02874608 |
62 | CSNK1G1 | 1.02209889 |
63 | RPS6KL1 | 1.01606540 |
64 | RPS6KC1 | 1.01606540 |
65 | DAPK1 | 0.99712760 |
66 | BRSK2 | 0.99267419 |
67 | LIMK1 | 0.95072990 |
68 | HIPK2 | 0.94056338 |
69 | MST4 | 0.92983680 |
70 | TEC | 0.92245617 |
71 | GRK6 | 0.91458236 |
72 | MATK | 0.90168491 |
73 | TNIK | 0.89679697 |
74 | CSNK1G2 | 0.89310156 |
75 | PNCK | 0.88468251 |
76 | MAPKAPK3 | 0.88175501 |
77 | GRK1 | 0.87447829 |
78 | MAP4K1 | 0.86826320 |
79 | CAMK1 | 0.86361377 |
80 | EIF2AK3 | 0.86351800 |
81 | KIT | 0.86345961 |
82 | PIM1 | 0.86047804 |
83 | BRSK1 | 0.84808007 |
84 | CHEK1 | 0.84802065 |
85 | RPS6KA6 | 0.84352858 |
86 | ZAK | 0.83966790 |
87 | PHKG1 | 0.83067871 |
88 | PHKG2 | 0.83067871 |
89 | FRK | 0.82760118 |
90 | LYN | 0.82246757 |
91 | DYRK1B | 0.80810382 |
92 | MAP3K6 | 0.78172632 |
93 | MAPK11 | 0.77893633 |
94 | STK16 | 0.77579192 |
95 | PLK2 | 0.72462960 |
96 | NEK9 | 0.72150573 |
97 | CSNK2A2 | 0.71357219 |
98 | CSNK1A1L | 0.70730710 |
99 | CDK3 | 0.70255839 |
100 | CSNK2A1 | 0.69259674 |
101 | ABL2 | 0.68975790 |
102 | CDK8 | 0.68455361 |
103 | TYK2 | 0.67831000 |
104 | AKT2 | 0.66110484 |
105 | EIF2AK2 | 0.63763643 |
106 | MAP2K7 | 0.63748933 |
107 | STK39 | 0.63739517 |
108 | MAP3K12 | 0.63532696 |
109 | CDK2 | 0.62743944 |
110 | ERBB4 | 0.61668149 |
111 | MAP2K6 | 0.61572078 |
112 | PBK | 0.61302722 |
113 | DYRK2 | 0.60994772 |
114 | DMPK | 0.60282936 |
115 | UHMK1 | 0.60049689 |
116 | ALK | 0.59414114 |
117 | TRPM7 | 0.58947903 |
118 | RPS6KA5 | 0.58506580 |
119 | ATM | 0.57792013 |
120 | PINK1 | 0.57627026 |
121 | CLK1 | 0.57562719 |
122 | PRKCG | 0.57257532 |
123 | TXK | 0.56009095 |
124 | EIF2AK1 | 0.53569074 |
125 | OXSR1 | 0.53550538 |
126 | FGR | 0.53465890 |
127 | TESK1 | 0.53057397 |
128 | NUAK1 | 0.52710925 |
129 | IKBKB | 0.52504146 |
130 | MAP3K4 | 0.48834963 |
131 | INSRR | 0.48000715 |
132 | BCKDK | 0.46676509 |
133 | CDK19 | 0.46634950 |
134 | FES | 0.45717221 |
135 | SIK3 | 0.45102577 |
136 | PRKCE | 0.44774382 |
137 | ADRBK2 | 0.44467379 |
138 | CSK | 0.43622297 |
139 | FLT3 | 0.43468579 |
140 | RPS6KA4 | 0.42886601 |
141 | MINK1 | 0.42356368 |
142 | PIK3CA | 0.41538632 |
143 | OBSCN | 0.39815327 |
144 | STK38L | 0.39492159 |
145 | PRKCI | 0.37054618 |
146 | CSNK1E | 0.34895966 |
147 | KDR | 0.31415492 |
148 | RIPK1 | 0.30993420 |
149 | CSNK1D | 0.27971978 |
150 | CDK1 | 0.26404995 |
151 | CSNK1A1 | 0.26146555 |
152 | NLK | 0.26125166 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Ribosome_Homo sapiens_hsa03010 | 5.12333447 |
2 | DNA replication_Homo sapiens_hsa03030 | 5.06308075 |
3 | Mismatch repair_Homo sapiens_hsa03430 | 4.66913880 |
4 | Base excision repair_Homo sapiens_hsa03410 | 3.76846929 |
5 | Homologous recombination_Homo sapiens_hsa03440 | 3.40926162 |
6 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 3.40654237 |
7 | Spliceosome_Homo sapiens_hsa03040 | 3.24390847 |
8 | RNA polymerase_Homo sapiens_hsa03020 | 3.05492873 |
9 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.86504658 |
10 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.66313869 |
11 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 2.46641246 |
12 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.41099160 |
13 | Proteasome_Homo sapiens_hsa03050 | 2.23214179 |
14 | Cell cycle_Homo sapiens_hsa04110 | 2.00606603 |
15 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.98301761 |
16 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.95631476 |
17 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.91462676 |
18 | RNA transport_Homo sapiens_hsa03013 | 1.84065831 |
19 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.74823168 |
20 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.73374039 |
21 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.69461526 |
22 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.69220510 |
23 | RNA degradation_Homo sapiens_hsa03018 | 1.66755512 |
24 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.60288862 |
25 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.58770826 |
26 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.55326439 |
27 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.53429164 |
28 | Basal transcription factors_Homo sapiens_hsa03022 | 1.50175869 |
29 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.48675247 |
30 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.37686660 |
31 | Purine metabolism_Homo sapiens_hsa00230 | 1.36799044 |
32 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.36072373 |
33 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.34348441 |
34 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 1.33565691 |
35 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.31908598 |
36 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.27262131 |
37 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 1.22553990 |
38 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.22547468 |
39 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 1.21812469 |
40 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.21588637 |
41 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.16130658 |
42 | Peroxisome_Homo sapiens_hsa04146 | 1.15439758 |
43 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.15322927 |
44 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 1.10941483 |
45 | Carbon metabolism_Homo sapiens_hsa01200 | 1.09166585 |
46 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.05190036 |
47 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 1.04345028 |
48 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.04099085 |
49 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.02057716 |
50 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 1.01385873 |
51 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.00321797 |
52 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.97990586 |
53 | Thyroid cancer_Homo sapiens_hsa05216 | 0.93551506 |
54 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.91937735 |
55 | Other glycan degradation_Homo sapiens_hsa00511 | 0.91574502 |
56 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.91517136 |
57 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.90684866 |
58 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.87470926 |
59 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.81116758 |
60 | Huntingtons disease_Homo sapiens_hsa05016 | 0.78631672 |
61 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.77683711 |
62 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.76952973 |
63 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.75412408 |
64 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.74789586 |
65 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.74400917 |
66 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.73016834 |
67 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.69744221 |
68 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.69156825 |
69 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.69124756 |
70 | Shigellosis_Homo sapiens_hsa05131 | 0.68354675 |
71 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.67073399 |
72 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.66816738 |
73 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.65279867 |
74 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.64534682 |
75 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.62755889 |
76 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.59830660 |
77 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.58875164 |
78 | Protein export_Homo sapiens_hsa03060 | 0.57650886 |
79 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.57383299 |
80 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.57083211 |
81 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.56031423 |
82 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.55035871 |
83 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.54268769 |
84 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.53429484 |
85 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.53090373 |
86 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.52926719 |
87 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.48069914 |
88 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.47605378 |
89 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.46120547 |
90 | Phototransduction_Homo sapiens_hsa04744 | 0.44871569 |
91 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.44420335 |
92 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.40060423 |
93 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.40056298 |
94 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.38832757 |
95 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.38569297 |
96 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.35373127 |
97 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.34491270 |
98 | Sulfur relay system_Homo sapiens_hsa04122 | 0.33872698 |
99 | Measles_Homo sapiens_hsa05162 | 0.33852398 |
100 | Parkinsons disease_Homo sapiens_hsa05012 | 0.33655470 |
101 | Metabolic pathways_Homo sapiens_hsa01100 | 0.33617983 |
102 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.33157612 |
103 | Retinol metabolism_Homo sapiens_hsa00830 | 0.32669419 |
104 | Apoptosis_Homo sapiens_hsa04210 | 0.32195051 |
105 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.31745936 |
106 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.31716414 |
107 | HTLV-I infection_Homo sapiens_hsa05166 | 0.30831902 |
108 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.30538689 |
109 | Hepatitis B_Homo sapiens_hsa05161 | 0.28610828 |
110 | Alcoholism_Homo sapiens_hsa05034 | 0.28025627 |
111 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.26864346 |
112 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.26448037 |
113 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.26317298 |
114 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.24010368 |
115 | Pathways in cancer_Homo sapiens_hsa05200 | 0.23184313 |
116 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.22893936 |
117 | Alzheimers disease_Homo sapiens_hsa05010 | 0.22603237 |
118 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.21800991 |
119 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.21693827 |
120 | Galactose metabolism_Homo sapiens_hsa00052 | 0.21650365 |
121 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.21538083 |
122 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.19640445 |
123 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.18618807 |
124 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.17976278 |
125 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.17707385 |
126 | Leishmaniasis_Homo sapiens_hsa05140 | 0.17386973 |
127 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.16174071 |
128 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.15796307 |
129 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.15791137 |
130 | Bladder cancer_Homo sapiens_hsa05219 | 0.15482183 |
131 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.14277554 |
132 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.13014024 |
133 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.12627389 |
134 | Melanoma_Homo sapiens_hsa05218 | 0.12491031 |
135 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.12453418 |
136 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.11681512 |
137 | Legionellosis_Homo sapiens_hsa05134 | 0.11114323 |
138 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.09931480 |
139 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.08665201 |
140 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.08474901 |
141 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.05926217 |
142 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.05506124 |
143 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.05163906 |
144 | Lysine degradation_Homo sapiens_hsa00310 | 0.05140423 |
145 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.04443998 |
146 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.03622763 |