PFDN2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a member of the prefoldin beta subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1proteasome assembly (GO:0043248)5.80954352
2ribosomal large subunit biogenesis (GO:0042273)5.52134726
3viral transcription (GO:0019083)5.25093540
4translational termination (GO:0006415)5.12235392
5ribosomal small subunit biogenesis (GO:0042274)5.09991653
6DNA deamination (GO:0045006)5.03302387
7ribosome assembly (GO:0042255)4.86717973
8ribonucleoprotein complex biogenesis (GO:0022613)4.71663793
9spliceosomal snRNP assembly (GO:0000387)4.68425142
10translational elongation (GO:0006414)4.66891217
11translational initiation (GO:0006413)4.63494200
12maturation of SSU-rRNA (GO:0030490)4.61850771
13ribosome biogenesis (GO:0042254)4.35965028
14protein complex biogenesis (GO:0070271)4.35429997
15ribosomal small subunit assembly (GO:0000028)4.32415276
16histone arginine methylation (GO:0034969)4.27627761
17SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.24976475
18establishment of protein localization to mitochondrial membrane (GO:0090151)4.23243376
19cellular protein complex disassembly (GO:0043624)4.21088964
20termination of RNA polymerase III transcription (GO:0006386)4.21050987
21transcription elongation from RNA polymerase III promoter (GO:0006385)4.21050987
22cotranslational protein targeting to membrane (GO:0006613)4.18562638
23protein targeting to ER (GO:0045047)4.16760404
24mitochondrial respiratory chain complex assembly (GO:0033108)4.15934164
25mitochondrial respiratory chain complex I biogenesis (GO:0097031)4.07152363
26mitochondrial respiratory chain complex I assembly (GO:0032981)4.07152363
27NADH dehydrogenase complex assembly (GO:0010257)4.07152363
28peptidyl-arginine omega-N-methylation (GO:0035247)4.07116647
29L-methionine biosynthetic process from methylthioadenosine (GO:0019509)4.05976213
30spliceosomal complex assembly (GO:0000245)4.02084293
31nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)4.02001477
32viral life cycle (GO:0019058)4.01344996
33translation (GO:0006412)4.00403072
34cellular component biogenesis (GO:0044085)3.99978839
35establishment of integrated proviral latency (GO:0075713)3.97796528
36protein localization to endoplasmic reticulum (GO:0070972)3.95747019
37pseudouridine synthesis (GO:0001522)3.94035153
38rRNA processing (GO:0006364)3.93176700
39establishment of protein localization to endoplasmic reticulum (GO:0072599)3.90380916
40cullin deneddylation (GO:0010388)3.78364461
41rRNA metabolic process (GO:0016072)3.76369676
42regulation of mitochondrial translation (GO:0070129)3.74571970
43mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.69774727
44negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.69696129
45protein complex disassembly (GO:0043241)3.69078948
46oxidative phosphorylation (GO:0006119)3.65681724
47L-methionine salvage (GO:0071267)3.63275346
48L-methionine biosynthetic process (GO:0071265)3.63275346
49amino acid salvage (GO:0043102)3.63275346
50deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.63272499
51establishment of protein localization to mitochondrion (GO:0072655)3.61885930
52macromolecular complex disassembly (GO:0032984)3.58691033
53nucleobase biosynthetic process (GO:0046112)3.55347597
54formation of translation preinitiation complex (GO:0001731)3.55342125
55signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.54820977
56signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.54820977
57purine nucleobase biosynthetic process (GO:0009113)3.53355956
587-methylguanosine mRNA capping (GO:0006370)3.53270205
59protein targeting to mitochondrion (GO:0006626)3.52548180
60peptidyl-arginine methylation (GO:0018216)3.52410439
61peptidyl-arginine N-methylation (GO:0035246)3.52410439
62ATP synthesis coupled proton transport (GO:0015986)3.49179491
63energy coupled proton transport, down electrochemical gradient (GO:0015985)3.49179491
64positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.48933130
65nucleobase-containing small molecule interconversion (GO:0015949)3.48300032
66anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.46821709
67protein deneddylation (GO:0000338)3.46522502
68RNA capping (GO:0036260)3.45272415
697-methylguanosine RNA capping (GO:0009452)3.45272415
70establishment of viral latency (GO:0019043)3.44861575
71maturation of 5.8S rRNA (GO:0000460)3.42766333
72respiratory chain complex IV assembly (GO:0008535)3.42624262
73signal transduction involved in cell cycle checkpoint (GO:0072395)3.42575460
74pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.42019736
75inner mitochondrial membrane organization (GO:0007007)3.41787394
76telomere maintenance via semi-conservative replication (GO:0032201)3.41408725
77rRNA modification (GO:0000154)3.40504612
78regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.39477171
79negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.39221189
80negative regulation of ligase activity (GO:0051352)3.39221189
81purine nucleoside triphosphate biosynthetic process (GO:0009145)3.37333524
82ATP biosynthetic process (GO:0006754)3.36855725
83DNA strand elongation involved in DNA replication (GO:0006271)3.35560620
84cytochrome complex assembly (GO:0017004)3.35264167
85purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.35115000
86protein maturation by protein folding (GO:0022417)3.34622759
87DNA replication checkpoint (GO:0000076)3.34006210
88nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.30455581
89RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.30289117
90tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.30289117
91GTP biosynthetic process (GO:0006183)3.29602704
92exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.26706654
93mitochondrial transport (GO:0006839)3.26245760
94folic acid-containing compound biosynthetic process (GO:0009396)3.25877245
95positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.24861417
96mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.23791863
97hydrogen ion transmembrane transport (GO:1902600)3.23693110
98regulation of cellular amino acid metabolic process (GO:0006521)3.23430603
99protein localization to mitochondrion (GO:0070585)3.22496061
100DNA damage response, detection of DNA damage (GO:0042769)3.21173692
101regulation of ubiquitin-protein transferase activity (GO:0051438)3.21032745
102RNA splicing, via transesterification reactions (GO:0000375)3.18082208
103ribonucleoside triphosphate biosynthetic process (GO:0009201)3.17775696
104DNA strand elongation (GO:0022616)3.17001517
105peptidyl-histidine modification (GO:0018202)3.16173639
106DNA replication initiation (GO:0006270)3.14852437
107RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)3.14474760
108mRNA splicing, via spliceosome (GO:0000398)3.14474760
109transcription from mitochondrial promoter (GO:0006390)3.13161292
110protein targeting to membrane (GO:0006612)3.12258772
111UTP biosynthetic process (GO:0006228)3.11531921
112protein neddylation (GO:0045116)3.10631251
113positive regulation of ligase activity (GO:0051351)3.10408586
114protein-cofactor linkage (GO:0018065)3.09393535
115protein complex localization (GO:0031503)3.08938792
116transcription-coupled nucleotide-excision repair (GO:0006283)3.07188923
117regulation of double-strand break repair via homologous recombination (GO:0010569)3.06263873
118respiratory electron transport chain (GO:0022904)3.02819904
119deoxyribonucleotide biosynthetic process (GO:0009263)3.02707709
120chaperone-mediated protein transport (GO:0072321)3.02600134
121DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.01502604
122pteridine-containing compound biosynthetic process (GO:0042559)3.00664068
123transcription from RNA polymerase I promoter (GO:0006360)2.98925222
124nuclear-transcribed mRNA catabolic process (GO:0000956)2.97424001
125termination of RNA polymerase II transcription (GO:0006369)2.97195269
126electron transport chain (GO:0022900)2.92811989
127signal transduction involved in DNA damage checkpoint (GO:0072422)2.91564160
128signal transduction involved in DNA integrity checkpoint (GO:0072401)2.91564160
129DNA-templated transcription, termination (GO:0006353)2.90993660
130intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)2.90987929
131signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)2.90987929
132regulation of nuclear cell cycle DNA replication (GO:0033262)2.90538814
133signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)2.90373851

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1MYC_18555785_ChIP-Seq_MESCs_Mouse5.04986014
2EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse4.09190825
3KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.92792795
4E2F7_22180533_ChIP-Seq_HELA_Human3.83196270
5NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.82009711
6EST1_17652178_ChIP-ChIP_JURKAT_Human3.79238219
7ETS1_20019798_ChIP-Seq_JURKAT_Human3.76072258
8* JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.64500120
9GABP_17652178_ChIP-ChIP_JURKAT_Human3.58381811
10MYC_19079543_ChIP-ChIP_MESCs_Mouse3.46134722
11* MYC_18358816_ChIP-ChIP_MESCs_Mouse3.35018807
12HCFC1_20581084_ChIP-Seq_MESCs_Mouse3.25181274
13CREB1_15753290_ChIP-ChIP_HEK293T_Human3.20962928
14* MYC_19030024_ChIP-ChIP_MESCs_Mouse3.09539981
15XRN2_22483619_ChIP-Seq_HELA_Human2.98795545
16HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.62943704
17THAP11_20581084_ChIP-Seq_MESCs_Mouse2.62796572
18CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.51740521
19SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.45405479
20E2F4_17652178_ChIP-ChIP_JURKAT_Human2.39684446
21FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.39432365
22TTF2_22483619_ChIP-Seq_HELA_Human2.38837107
23* VDR_23849224_ChIP-Seq_CD4+_Human2.33246409
24DCP1A_22483619_ChIP-Seq_HELA_Human2.32056104
25* E2F1_18555785_ChIP-Seq_MESCs_Mouse2.31860362
26YY1_21170310_ChIP-Seq_MESCs_Mouse2.13799340
27* GABP_19822575_ChIP-Seq_HepG2_Human2.11583168
28NELFA_20434984_ChIP-Seq_ESCs_Mouse2.10153311
29FOXP3_21729870_ChIP-Seq_TREG_Human2.05148119
30POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.98768625
31E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.87481240
32* ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.87406733
33FOXM1_23109430_ChIP-Seq_U2OS_Human1.85123857
34TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.72794925
35MYCN_18555785_ChIP-Seq_MESCs_Mouse1.68309555
36PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.62612326
37POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.57595558
38KDM5A_27292631_Chip-Seq_BREAST_Human1.56148522
39ELF1_17652178_ChIP-ChIP_JURKAT_Human1.55252449
40NANOG_18555785_ChIP-Seq_MESCs_Mouse1.55103252
41MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.55034077
42MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.54992558
43ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.52156731
44MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.51873082
45ZFX_18555785_ChIP-Seq_MESCs_Mouse1.51207866
46ELK1_22589737_ChIP-Seq_MCF10A_Human1.48404372
47SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.47053772
48KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.45887902
49* YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.45758349
50PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.45455290
51* SRF_21415370_ChIP-Seq_HL-1_Mouse1.44980709
52ZNF263_19887448_ChIP-Seq_K562_Human1.42421280
53CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.40495143
54CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.39997118
55* CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.39657274
56ELK1_19687146_ChIP-ChIP_HELA_Human1.36615104
57CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.35325088
58POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.33871252
59MYC_18940864_ChIP-ChIP_HL60_Human1.31813822
60BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.30889087
61SRY_22984422_ChIP-ChIP_TESTIS_Rat1.29902621
62ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.29047843
63DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.25673356
64FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.23234592
65AR_21909140_ChIP-Seq_LNCAP_Human1.21039917
66OCT4_18692474_ChIP-Seq_MEFs_Mouse1.20603905
67* TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.18959017
68CIITA_25753668_ChIP-Seq_RAJI_Human1.17558783
69CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.17469107
70SOX2_18692474_ChIP-Seq_MEFs_Mouse1.16261674
71* FOXP1_21924763_ChIP-Seq_HESCs_Human1.14374194
72* KLF4_18555785_ChIP-Seq_MESCs_Mouse1.13539878
73KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.13538524
74KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.13538524
75KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.13538524
76STAT3_1855785_ChIP-Seq_MESCs_Mouse1.12311818
77ERG_20887958_ChIP-Seq_HPC-7_Mouse1.08601206
78E2F1_21310950_ChIP-Seq_MCF-7_Human1.08449357
79KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.07593071
80YY1_22570637_ChIP-Seq_MALME-3M_Human1.07162499
81PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.05850539
82SOX2_18555785_ChIP-Seq_MESCs_Mouse1.05726156
83CTCF_18555785_ChIP-Seq_MESCs_Mouse1.04816189
84SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.04619428
85DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.04029644
86NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.03263008
87NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.02982100
88CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.01192371
89NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.00525390
90ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.00220922
91TCF3_18692474_ChIP-Seq_MEFs_Mouse1.00071354
92* SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.99111487
93CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.95751746
94TFEB_21752829_ChIP-Seq_HELA_Human0.94931026
95* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.93399931
96* HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.93308593
97ESR1_15608294_ChIP-ChIP_MCF-7_Human0.93242790
98HOXB4_20404135_ChIP-ChIP_EML_Mouse0.92472971
99* FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.91756724
100* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.89517492
101NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.89026374
102SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.88816197
103CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.88738273
104TBX5_21415370_ChIP-Seq_HL-1_Mouse0.88524793
105POU5F1_18692474_ChIP-Seq_MESCs_Mouse0.87466633
106HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.86877470
107CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.86448075
108* ATF3_23680149_ChIP-Seq_GBM1-GSC_Human0.85933172
109SETDB1_19884255_ChIP-Seq_MESCs_Mouse0.85785910
110TET1_21451524_ChIP-Seq_MESCs_Mouse0.84446410
111NANOG_21062744_ChIP-ChIP_HESCs_Human0.84395317
112PADI4_21655091_ChIP-ChIP_MCF-7_Human0.83607276
113TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.83469677
114SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.83459208
115* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.82086677
116* GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.79722544

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009379_abnormal_foot_pigmentation4.45826895
2MP0003693_abnormal_embryo_hatching4.15705730
3MP0004957_abnormal_blastocyst_morpholog3.65627673
4MP0003111_abnormal_nucleus_morphology2.93835472
5MP0001188_hyperpigmentation2.85316938
6MP0003880_abnormal_central_pattern2.84493412
7MP0008932_abnormal_embryonic_tissue2.80617682
8MP0003077_abnormal_cell_cycle2.43177937
9MP0003718_maternal_effect2.37434798
10MP0003123_paternal_imprinting2.33324659
11MP0010094_abnormal_chromosome_stability2.32019033
12MP0006292_abnormal_olfactory_placode2.24546404
13MP0006276_abnormal_autonomic_nervous2.05133937
14MP0004142_abnormal_muscle_tone1.99821998
15MP0008058_abnormal_DNA_repair1.95322269
16MP0008877_abnormal_DNA_methylation1.89858932
17MP0001968_abnormal_touch/_nociception1.87536452
18MP0008260_abnormal_autophagy1.79711378
19MP0008007_abnormal_cellular_replicative1.79241780
20MP0010030_abnormal_orbit_morphology1.76676705
21MP0003786_premature_aging1.73062106
22MP0002653_abnormal_ependyma_morphology1.71733533
23MP0009697_abnormal_copulation1.71201327
24MP0002160_abnormal_reproductive_system1.66936976
25MP0004859_abnormal_synaptic_plasticity1.61329074
26MP0003941_abnormal_skin_development1.61190904
27MP0001529_abnormal_vocalization1.60559932
28MP0002234_abnormal_pharynx_morphology1.60156749
29MP0006035_abnormal_mitochondrial_morpho1.60129560
30MP0002736_abnormal_nociception_after1.59587571
31MP0002751_abnormal_autonomic_nervous1.53223236
32MP0004133_heterotaxia1.52890406
33MP0003646_muscle_fatigue1.50964950
34MP0000350_abnormal_cell_proliferation1.47378143
35MP0002163_abnormal_gland_morphology1.46667304
36MP0008995_early_reproductive_senescence1.45441948
37MP0003136_yellow_coat_color1.42420103
38MP0006036_abnormal_mitochondrial_physio1.37939296
39MP0008057_abnormal_DNA_replication1.37203677
40MP0005084_abnormal_gallbladder_morpholo1.36399144
41MP0002638_abnormal_pupillary_reflex1.35099610
42MP0000372_irregular_coat_pigmentation1.33805672
43MP0003119_abnormal_digestive_system1.32162293
44MP0003635_abnormal_synaptic_transmissio1.31092050
45MP0001730_embryonic_growth_arrest1.29159737
46MP0009053_abnormal_anal_canal1.27468971
47MP0005389_reproductive_system_phenotype1.26495199
48MP0005645_abnormal_hypothalamus_physiol1.23697082
49MP0001919_abnormal_reproductive_system1.23537474
50MP0000678_abnormal_parathyroid_gland1.21466465
51MP0003567_abnormal_fetal_cardiomyocyte1.21192258
52MP0002938_white_spotting1.20810196
53MP0009046_muscle_twitch1.20575322
54MP0001905_abnormal_dopamine_level1.20144664
55MP0002064_seizures1.20084150
56MP0002139_abnormal_hepatobiliary_system1.20008536
57MP0002734_abnormal_mechanical_nocicepti1.14639268
58MP0002837_dystrophic_cardiac_calcinosis1.14633383
59MP0008789_abnormal_olfactory_epithelium1.13889763
60MP0000750_abnormal_muscle_regeneration1.13822153
61MP0009745_abnormal_behavioral_response1.12886742
62MP0006072_abnormal_retinal_apoptosis1.12300474
63MP0005499_abnormal_olfactory_system1.10686785
64MP0005394_taste/olfaction_phenotype1.10686785
65MP0001697_abnormal_embryo_size1.09681955
66MP0001881_abnormal_mammary_gland1.09309145
67MP0000049_abnormal_middle_ear1.08617526
68MP0003122_maternal_imprinting1.08469415
69MP0005501_abnormal_skin_physiology1.07776504
70MP0003890_abnormal_embryonic-extraembry1.07735420
71MP0002063_abnormal_learning/memory/cond1.07004515
72MP0003938_abnormal_ear_development1.06993563
73MP0003315_abnormal_perineum_morphology1.06862951
74MP0003186_abnormal_redox_activity1.06718633
75MP0003806_abnormal_nucleotide_metabolis1.06494132
76MP0002572_abnormal_emotion/affect_behav1.05425326
77MP0004270_analgesia1.04188604
78MP0002877_abnormal_melanocyte_morpholog1.03850340
79MP0002080_prenatal_lethality1.03583740
80MP0001727_abnormal_embryo_implantation1.01508781
81MP0001672_abnormal_embryogenesis/_devel1.01411804
82MP0005380_embryogenesis_phenotype1.01411804
83MP0001970_abnormal_pain_threshold1.00857828
84MP0002085_abnormal_embryonic_tissue1.00704460
85MP0002177_abnormal_outer_ear1.00501584
86MP0001764_abnormal_homeostasis1.00429771
87MP0001293_anophthalmia1.00157296
88MP0001984_abnormal_olfaction0.99797508
89MP0000313_abnormal_cell_death0.98411233
90MP0002733_abnormal_thermal_nociception0.97756816
91MP0002277_abnormal_respiratory_mucosa0.96289340
92MP0000358_abnormal_cell_content/0.95886833
93MP0001440_abnormal_grooming_behavior0.95182292
94MP0002210_abnormal_sex_determination0.93408570
95MP0001929_abnormal_gametogenesis0.93320343
96MP0009672_abnormal_birth_weight0.91442140
97MP0002184_abnormal_innervation0.88059216
98MP0002272_abnormal_nervous_system0.87545151
99MP0002557_abnormal_social/conspecific_i0.87398864
100MP0000653_abnormal_sex_gland0.87072200
101MP0002132_abnormal_respiratory_system0.86120348
102MP0003984_embryonic_growth_retardation0.82597960
103MP0002088_abnormal_embryonic_growth/wei0.81402888
104MP0001853_heart_inflammation0.80943683
105MP0002084_abnormal_developmental_patter0.80875411
106MP0002735_abnormal_chemical_nociception0.80561809
107MP0001145_abnormal_male_reproductive0.80434498
108MP0002102_abnormal_ear_morphology0.79937767
109MP0001542_abnormal_bone_strength0.79387559
110MP0002822_catalepsy0.79126398
111MP0002095_abnormal_skin_pigmentation0.78704071
112MP0000647_abnormal_sebaceous_gland0.78143055
113MP0005646_abnormal_pituitary_gland0.77982538
114MP0000749_muscle_degeneration0.77056558
115MP0009250_abnormal_appendicular_skeleto0.76998292
116MP0004811_abnormal_neuron_physiology0.75981158
117MP0005410_abnormal_fertilization0.75975283
118MP0005423_abnormal_somatic_nervous0.75753649
119MP0005670_abnormal_white_adipose0.75524104
120MP0003303_peritoneal_inflammation0.75514116
121MP0005408_hypopigmentation0.74471834
122MP0004145_abnormal_muscle_electrophysio0.73932815
123MP0002067_abnormal_sensory_capabilities0.73390394
124MP0009333_abnormal_splenocyte_physiolog0.72374445
125MP0003861_abnormal_nervous_system0.72241578
126MP0002066_abnormal_motor_capabilities/c0.71646648
127MP0003942_abnormal_urinary_system0.71474473
128MP0000762_abnormal_tongue_morphology0.71030578
129MP0005330_cardiomyopathy0.70106338
130MP0000428_abnormal_craniofacial_morphol0.69088897
131MP0005266_abnormal_metabolism0.68959650
132MP0003121_genomic_imprinting0.67470835
133MP0000631_abnormal_neuroendocrine_gland0.66975225
134MP0001502_abnormal_circadian_rhythm0.64468800
135MP0003937_abnormal_limbs/digits/tail_de0.63566621
136MP0004147_increased_porphyrin_level0.63498121

Predicted human phenotypes

RankGene SetZ-score
1Cerebral hypomyelination (HP:0006808)4.02241040
2Renal Fanconi syndrome (HP:0001994)3.99393951
3Acute necrotizing encephalopathy (HP:0006965)3.91060147
4Hepatocellular necrosis (HP:0001404)3.87739922
5Mitochondrial inheritance (HP:0001427)3.78743580
6Abnormal mitochondria in muscle tissue (HP:0008316)3.66397741
7Abnormality of the labia minora (HP:0012880)3.63996563
8Macrocytic anemia (HP:0001972)3.59532107
9Breast hypoplasia (HP:0003187)3.58670215
10Decreased activity of mitochondrial respiratory chain (HP:0008972)3.57972445
11Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.57972445
12Increased muscle lipid content (HP:0009058)3.44115097
13Abnormality of cells of the erythroid lineage (HP:0012130)3.40919730
14Increased CSF lactate (HP:0002490)3.35757624
15Reticulocytopenia (HP:0001896)3.31329684
16Acute encephalopathy (HP:0006846)3.29472001
17Progressive external ophthalmoplegia (HP:0000590)3.21824524
18Abnormal number of erythroid precursors (HP:0012131)3.20794433
19Progressive macrocephaly (HP:0004481)3.19391688
20Muscle abnormality related to mitochondrial dysfunction (HP:0003800)3.18013611
21Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.15049270
22Hepatic necrosis (HP:0002605)3.14479522
23Increased serum lactate (HP:0002151)3.09258796
24Birth length less than 3rd percentile (HP:0003561)2.94832877
25Supernumerary spleens (HP:0009799)2.94826081
26Oral leukoplakia (HP:0002745)2.94143429
27Trismus (HP:0000211)2.87312304
28Secondary amenorrhea (HP:0000869)2.87266339
29Rough bone trabeculation (HP:0100670)2.84892320
30Abnormality of glycolysis (HP:0004366)2.83954596
31Increased serum pyruvate (HP:0003542)2.83954596
32Shoulder girdle muscle weakness (HP:0003547)2.80982116
33Patellar aplasia (HP:0006443)2.74389835
34Type I transferrin isoform profile (HP:0003642)2.73531922
35Emotional lability (HP:0000712)2.67483327
36Aplasia/Hypoplasia of the patella (HP:0006498)2.66746783
37Progressive muscle weakness (HP:0003323)2.66111135
38Myokymia (HP:0002411)2.63894125
39Respiratory difficulties (HP:0002880)2.61264198
40Poor suck (HP:0002033)2.61122816
41Respiratory failure (HP:0002878)2.61000668
423-Methylglutaconic aciduria (HP:0003535)2.59706095
43Testicular atrophy (HP:0000029)2.59177291
44Exercise intolerance (HP:0003546)2.56996376
45Unsteady gait (HP:0002317)2.55678037
46Concave nail (HP:0001598)2.53630666
47CNS demyelination (HP:0007305)2.51501432
48Increased hepatocellular lipid droplets (HP:0006565)2.50711171
49Aplasia/Hypoplasia of the sacrum (HP:0008517)2.50074705
50Abnormality of the anterior horn cell (HP:0006802)2.48645887
51Degeneration of anterior horn cells (HP:0002398)2.48645887
52Horseshoe kidney (HP:0000085)2.46171410
53Carpal bone hypoplasia (HP:0001498)2.44287184
54Pallor (HP:0000980)2.42761213
55Lactic acidosis (HP:0003128)2.41637989
56Absent radius (HP:0003974)2.40870779
57Focal motor seizures (HP:0011153)2.40656623
58Generalized aminoaciduria (HP:0002909)2.38216777
59Delusions (HP:0000746)2.36393046
60Absent forearm bone (HP:0003953)2.36328282
61Aplasia involving forearm bones (HP:0009822)2.36328282
62Aplasia/hypoplasia of the uterus (HP:0008684)2.35942425
63Obstructive sleep apnea (HP:0002870)2.33312366
64Methylmalonic aciduria (HP:0012120)2.31217331
65Optic disc pallor (HP:0000543)2.30622727
66Cerebral edema (HP:0002181)2.29605672
67Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.28040193
68Aplastic anemia (HP:0001915)2.27966470
69Hyperglycinemia (HP:0002154)2.26434570
70Pancytopenia (HP:0001876)2.26318034
71Sleep apnea (HP:0010535)2.24201734
72Absent thumb (HP:0009777)2.20928590
73CNS hypomyelination (HP:0003429)2.19967998
74Triphalangeal thumb (HP:0001199)2.19929305
75Premature ovarian failure (HP:0008209)2.18560669
76Abnormality of renal resorption (HP:0011038)2.17821490
77Increased intramyocellular lipid droplets (HP:0012240)2.17683566
78X-linked dominant inheritance (HP:0001423)2.15713802
79Multiple enchondromatosis (HP:0005701)2.14931592
80Cleft eyelid (HP:0000625)2.14584845
81Microretrognathia (HP:0000308)2.13547711
82Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.11960737
83Abnormal protein N-linked glycosylation (HP:0012347)2.11960737
84Abnormal protein glycosylation (HP:0012346)2.11960737
85Abnormal glycosylation (HP:0012345)2.11960737
86Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.11313217
87Lipid accumulation in hepatocytes (HP:0006561)2.10319611
88Microvesicular hepatic steatosis (HP:0001414)2.10085717
89Abnormal trabecular bone morphology (HP:0100671)2.06130710
90Pelvic girdle muscle weakness (HP:0003749)2.05535332
91Congenital, generalized hypertrichosis (HP:0004540)2.05065227
92External ophthalmoplegia (HP:0000544)2.04587074
93Abnormality of placental membranes (HP:0011409)2.02917948
94Amniotic constriction ring (HP:0009775)2.02917948
95Aplasia/Hypoplasia involving the musculature (HP:0001460)2.00725348
96Exertional dyspnea (HP:0002875)2.00210282
97Premature graying of hair (HP:0002216)2.00053382
98Methylmalonic acidemia (HP:0002912)1.99330534
99Lethargy (HP:0001254)1.98144667
100Reduced antithrombin III activity (HP:0001976)1.97272027
101Leukodystrophy (HP:0002415)1.93508075
102Breast aplasia (HP:0100783)1.92784706
103Abnormality of the hip-girdle musculature (HP:0001445)1.92751258
104Abnormality of the musculature of the pelvis (HP:0001469)1.92751258
105Abnormality of pyrimidine metabolism (HP:0004353)1.91496895
106Megaloblastic anemia (HP:0001889)1.89486804
107Meckel diverticulum (HP:0002245)1.89030548
108Aplasia/Hypoplasia of the breasts (HP:0010311)1.88752436
109Sparse eyelashes (HP:0000653)1.85674760
110Abnormal hemoglobin (HP:0011902)1.84264449
111Abnormality of the ileum (HP:0001549)1.83662360
112Atrophy/Degeneration involving motor neurons (HP:0007373)1.81506404
113Ragged-red muscle fibers (HP:0003200)1.80638688
114Abnormality of aromatic amino acid family metabolism (HP:0004338)1.79400109
115Abnormality of alanine metabolism (HP:0010916)1.79001096
116Hyperalaninemia (HP:0003348)1.79001096
117Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.79001096
118Abnormality of serum amino acid levels (HP:0003112)1.78593138
119Rhabdomyosarcoma (HP:0002859)1.78555646
120Abnormality of dicarboxylic acid metabolism (HP:0010995)1.78067151
121Dicarboxylic aciduria (HP:0003215)1.78067151
122Spastic paraparesis (HP:0002313)1.77259975
123Delayed CNS myelination (HP:0002188)1.75526195
124Glycosuria (HP:0003076)1.74624535
125Abnormality of urine glucose concentration (HP:0011016)1.74624535
126Blindness (HP:0000618)1.72844460
127Muscle fiber atrophy (HP:0100295)1.71570992
128Upper limb muscle weakness (HP:0003484)1.68843824
129Hyperphosphaturia (HP:0003109)1.64988285
130Progressive microcephaly (HP:0000253)1.64618135
131Sensory axonal neuropathy (HP:0003390)1.63150183
132Opisthotonus (HP:0002179)1.56571714
133Retinal dysplasia (HP:0007973)1.55927202
134Abnormality of magnesium homeostasis (HP:0004921)1.54812133
135Vomiting (HP:0002013)1.54583352
136Congenital ichthyosiform erythroderma (HP:0007431)1.54478781
137Abnormality of midbrain morphology (HP:0002418)1.52887628
138Molar tooth sign on MRI (HP:0002419)1.52887628
139Abnormality of methionine metabolism (HP:0010901)1.51760592

Predicted kinase interactions (KEA)

RankGene SetZ-score
1VRK25.08289718
2EIF2AK14.56286200
3BUB14.10656987
4EIF2AK33.78830743
5TESK23.28212915
6WEE13.06279660
7TLK12.92360145
8MKNK22.70241508
9NME22.36107370
10PIM22.33134350
11LIMK12.32991296
12PBK2.31013074
13SRPK12.15561015
14MST42.07713632
15MKNK12.06893781
16STK161.99570179
17CASK1.94769270
18TSSK61.90384909
19NME11.71709733
20ARAF1.67146965
21CDK191.65869617
22PNCK1.64698203
23LATS21.58121473
24NEK11.57542721
25PLK41.57276399
26BRAF1.56604366
27MINK11.51555404
28PDK21.47698783
29MAP3K111.46616900
30MAP3K121.45324668
31CDC71.39296372
32AURKA1.34532991
33UHMK11.29773947
34TRIM281.28921862
35KDR1.27519183
36NEK91.26901828
37DYRK31.26386173
38PLK11.23802461
39AKT31.23777123
40PINK11.19119218
41TESK11.18518606
42DAPK11.16277709
43CSNK1G31.13534024
44EIF2AK21.12136504
45MAP2K71.08723826
46VRK11.03127478
47PLK31.01048017
48TTK1.00917836
49DYRK21.00178136
50MAPKAPK30.97627155
51MAP4K20.97107291
52SIK30.93530505
53ALK0.93094535
54CDK70.88347813
55ATR0.83218285
56CSNK1G20.83194453
57SCYL20.82421850
58NUAK10.82083328
59BCKDK0.81993459
60PAK10.79367325
61DAPK30.78545492
62CSNK1A1L0.78098159
63CCNB10.77157475
64STK380.76298548
65FES0.76191739
66LRRK20.75753710
67CDK80.75425141
68ABL20.72159748
69MARK10.70964860
70CDK140.69933469
71CSNK2A10.69319950
72BCR0.68890204
73ZAK0.66118944
74CSNK2A20.65342724
75RPS6KA40.64781571
76CSNK1E0.64612943
77ERBB40.63963909
78BRSK10.63791165
79IRAK30.62894957
80NTRK30.62061275
81CDK180.60733092
82STK38L0.58883523
83PAK40.58090221
84YES10.57799634
85AURKB0.57373617
86WNK40.57313558
87CDK11A0.57217206
88ILK0.56427744
89CDK150.56192343
90DYRK1B0.55726807
91MST1R0.54999646
92GRK60.54967765
93RPS6KA50.54838434
94MAP2K60.54570602
95BRSK20.53976380
96BMPR1B0.53657193
97CAMK2G0.52471158
98TAOK20.52220255
99CAMK2B0.50405542
100STK40.50239127
101MAP2K40.49874097
102NTRK10.49366850
103PRKCI0.46855176
104PRKCG0.46309140
105TAOK10.46246654
106TAF10.45869024
107NLK0.45807089
108MAP3K80.44288514
109PHKG10.43435546
110PHKG20.43435546
111CAMKK20.42819749
112MAPKAPK50.41779314
113GRK50.41718543
114CDK20.41510419
115MAP3K40.40972503
116FLT30.40523136
117PIM10.39953868
118AKT20.39430368
119LMTK20.39302542
120CHEK20.39285677
121MOS0.39115334
122PLK20.38889057
123ATM0.37478657
124EPHA20.36267403
125CSNK1G10.34611837
126IRAK20.33658366
127NEK20.33050039
128CSNK1A10.32742222
129ACVR1B0.31250391
130CHEK10.29925366
131FER0.29512263

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030105.30223512
2Proteasome_Homo sapiens_hsa030504.18782341
3RNA polymerase_Homo sapiens_hsa030203.99400387
4Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.56066620
5DNA replication_Homo sapiens_hsa030303.54352101
6Spliceosome_Homo sapiens_hsa030403.49042092
7Oxidative phosphorylation_Homo sapiens_hsa001903.00250406
8Parkinsons disease_Homo sapiens_hsa050122.86387953
9Mismatch repair_Homo sapiens_hsa034302.62886993
10RNA transport_Homo sapiens_hsa030132.62684031
11Pyrimidine metabolism_Homo sapiens_hsa002402.59289943
12Homologous recombination_Homo sapiens_hsa034402.30811570
13Huntingtons disease_Homo sapiens_hsa050162.30538993
14Nucleotide excision repair_Homo sapiens_hsa034202.17467424
15Base excision repair_Homo sapiens_hsa034102.10506345
16Basal transcription factors_Homo sapiens_hsa030222.04755441
17One carbon pool by folate_Homo sapiens_hsa006701.99687121
18Alzheimers disease_Homo sapiens_hsa050101.76055200
19Sulfur relay system_Homo sapiens_hsa041221.74008092
20Cyanoamino acid metabolism_Homo sapiens_hsa004601.64014324
21Vitamin B6 metabolism_Homo sapiens_hsa007501.63005266
22Folate biosynthesis_Homo sapiens_hsa007901.52215418
23Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.50903076
24Cell cycle_Homo sapiens_hsa041101.45043928
25mRNA surveillance pathway_Homo sapiens_hsa030151.37188746
26Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.34416785
27Cysteine and methionine metabolism_Homo sapiens_hsa002701.34253676
28Purine metabolism_Homo sapiens_hsa002301.33531674
29RNA degradation_Homo sapiens_hsa030181.28489385
30Protein export_Homo sapiens_hsa030601.25695848
31Cardiac muscle contraction_Homo sapiens_hsa042601.21511651
32Fanconi anemia pathway_Homo sapiens_hsa034601.18195781
33Synaptic vesicle cycle_Homo sapiens_hsa047211.17549471
34Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.15194760
35Biosynthesis of amino acids_Homo sapiens_hsa012301.12736039
36Fatty acid elongation_Homo sapiens_hsa000621.11449551
37Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.08426899
38Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.07314750
39Oocyte meiosis_Homo sapiens_hsa041141.06630657
40Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.95955954
41Sulfur metabolism_Homo sapiens_hsa009200.89434721
42Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.86451470
43Epstein-Barr virus infection_Homo sapiens_hsa051690.85413851
44p53 signaling pathway_Homo sapiens_hsa041150.84587418
45Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.79800864
46Nicotine addiction_Homo sapiens_hsa050330.77528370
47Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.74848633
48Thyroid cancer_Homo sapiens_hsa052160.74174783
49Carbon metabolism_Homo sapiens_hsa012000.71466908
50Glutathione metabolism_Homo sapiens_hsa004800.71391084
51Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.71314094
52Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.69796590
53Pentose phosphate pathway_Homo sapiens_hsa000300.68881367
54Collecting duct acid secretion_Homo sapiens_hsa049660.66498158
55Regulation of autophagy_Homo sapiens_hsa041400.65795116
56Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.64891246
57Drug metabolism - other enzymes_Homo sapiens_hsa009830.63191562
58Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.60234026
592-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.57030575
60Olfactory transduction_Homo sapiens_hsa047400.55685345
61Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.53402159
62Metabolic pathways_Homo sapiens_hsa011000.52504468
63Propanoate metabolism_Homo sapiens_hsa006400.50918868
64Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.49718646
65Vibrio cholerae infection_Homo sapiens_hsa051100.49081629
66Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.48833455
67Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.47993677
68N-Glycan biosynthesis_Homo sapiens_hsa005100.47283039
69Selenocompound metabolism_Homo sapiens_hsa004500.45363317
70Steroid biosynthesis_Homo sapiens_hsa001000.45086098
71Arginine and proline metabolism_Homo sapiens_hsa003300.43569321
72Peroxisome_Homo sapiens_hsa041460.42342495
73Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.41298807
74Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.38613710
75Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.38582085
76Non-homologous end-joining_Homo sapiens_hsa034500.35397589
77Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.35212213
78SNARE interactions in vesicular transport_Homo sapiens_hsa041300.33703390
79Bladder cancer_Homo sapiens_hsa052190.30254572
80GABAergic synapse_Homo sapiens_hsa047270.28874933
81Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.28166490
82Amphetamine addiction_Homo sapiens_hsa050310.27612434
83Arginine biosynthesis_Homo sapiens_hsa002200.27512554
84Pyruvate metabolism_Homo sapiens_hsa006200.27077856
85Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.26955739
86Shigellosis_Homo sapiens_hsa051310.25023213
87Fructose and mannose metabolism_Homo sapiens_hsa000510.24251583
88Long-term potentiation_Homo sapiens_hsa047200.23095747
89Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.23006716
90Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.22961480
91Phenylalanine metabolism_Homo sapiens_hsa003600.22042855
92Rheumatoid arthritis_Homo sapiens_hsa053230.21622884
93Dopaminergic synapse_Homo sapiens_hsa047280.20929268
94Wnt signaling pathway_Homo sapiens_hsa043100.17827442
95Phototransduction_Homo sapiens_hsa047440.17815131
96Galactose metabolism_Homo sapiens_hsa000520.16048598
97Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.13975419
98Long-term depression_Homo sapiens_hsa047300.13192697
99Melanoma_Homo sapiens_hsa052180.11389496
100Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.10775863
101HIF-1 signaling pathway_Homo sapiens_hsa040660.10194340
102Melanogenesis_Homo sapiens_hsa049160.10001643
103Hippo signaling pathway_Homo sapiens_hsa043900.09598383
104Tyrosine metabolism_Homo sapiens_hsa003500.09460527
105Butanoate metabolism_Homo sapiens_hsa006500.09345001
106Arachidonic acid metabolism_Homo sapiens_hsa005900.08400550
107Gap junction_Homo sapiens_hsa045400.08194161
108beta-Alanine metabolism_Homo sapiens_hsa004100.08134929
109Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.07694639
110Serotonergic synapse_Homo sapiens_hsa047260.07455111
111Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.07436956
112Asthma_Homo sapiens_hsa053100.06298769
113Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.05924579
114Hedgehog signaling pathway_Homo sapiens_hsa043400.03570524
115Fatty acid metabolism_Homo sapiens_hsa012120.02685836
116Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.02330512
117Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.01654901
118Pentose and glucuronate interconversions_Homo sapiens_hsa000400.01108158
119Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.00273069
120Salmonella infection_Homo sapiens_hsa05132-0.0150639

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