

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | protein maturation by protein folding (GO:0022417) | 6.73109409 |
| 2 | establishment of viral latency (GO:0019043) | 5.73829411 |
| 3 | extracellular fibril organization (GO:0043206) | 5.65473084 |
| 4 | response to gravity (GO:0009629) | 5.34665815 |
| 5 | galactose catabolic process (GO:0019388) | 5.19905690 |
| 6 | establishment of integrated proviral latency (GO:0075713) | 5.00005831 |
| 7 | mitotic nuclear envelope reassembly (GO:0007084) | 4.82704399 |
| 8 | nuclear envelope reassembly (GO:0031468) | 4.82704399 |
| 9 | endothelial tube morphogenesis (GO:0061154) | 4.80759747 |
| 10 | morphogenesis of an endothelium (GO:0003159) | 4.80759747 |
| 11 | detection of chemical stimulus involved in sensory perception of bitter taste (GO:0001580) | 4.66124926 |
| 12 | positive regulation of actin filament depolymerization (GO:0030836) | 4.65619582 |
| 13 | fibril organization (GO:0097435) | 4.51538316 |
| 14 | proteasome assembly (GO:0043248) | 4.44927201 |
| 15 | sequestering of actin monomers (GO:0042989) | 4.31521831 |
| 16 | mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003337) | 4.21516967 |
| 17 | glomerular visceral epithelial cell development (GO:0072015) | 4.18549835 |
| 18 | negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471) | 4.17389373 |
| 19 | positive regulation of mitochondrial calcium ion concentration (GO:0051561) | 4.15931817 |
| 20 | type B pancreatic cell proliferation (GO:0044342) | 4.13638050 |
| 21 | protein retention in ER lumen (GO:0006621) | 4.12880955 |
| 22 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 4.11146198 |
| 23 | negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315) | 4.11063212 |
| 24 | detection of chemical stimulus involved in sensory perception of taste (GO:0050912) | 4.00184863 |
| 25 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.93356380 |
| 26 | positive regulation of mitochondrial fission (GO:0090141) | 3.91561613 |
| 27 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.89261836 |
| 28 | galactose metabolic process (GO:0006012) | 3.87293014 |
| 29 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.79207365 |
| 30 | maintenance of protein localization in endoplasmic reticulum (GO:0035437) | 3.66816725 |
| 31 | glomerular epithelial cell development (GO:0072310) | 3.65550317 |
| 32 | negative regulation of ligase activity (GO:0051352) | 3.64636891 |
| 33 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.64636891 |
| 34 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.58521238 |
| 35 | mesonephros development (GO:0001823) | 3.55498334 |
| 36 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.53936469 |
| 37 | Golgi transport vesicle coating (GO:0048200) | 3.53329344 |
| 38 | COPI coating of Golgi vesicle (GO:0048205) | 3.53329344 |
| 39 | mesenchymal cell differentiation involved in renal system development (GO:2001012) | 3.51450448 |
| 40 | mesenchymal cell differentiation involved in kidney development (GO:0072161) | 3.51450448 |
| 41 | lipopolysaccharide biosynthetic process (GO:0009103) | 3.50544415 |
| 42 | regulation of metalloenzyme activity (GO:0048552) | 3.50049103 |
| 43 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.42024482 |
| 44 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.42024482 |
| 45 | pattern specification involved in kidney development (GO:0061004) | 3.39169023 |
| 46 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.38730972 |
| 47 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.38730972 |
| 48 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.38730972 |
| 49 | actin filament depolymerization (GO:0030042) | 3.38239287 |
| 50 | muscle cell migration (GO:0014812) | 3.29231305 |
| 51 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 3.28042349 |
| 52 | regulation of mitochondrial translation (GO:0070129) | 3.27581215 |
| 53 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.23854741 |
| 54 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.23854741 |
| 55 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.18532043 |
| 56 | protein heterotetramerization (GO:0051290) | 3.13908780 |
| 57 | cullin deneddylation (GO:0010388) | 3.07270932 |
| 58 | regulation of cilium movement (GO:0003352) | 3.03663455 |
| 59 | positive regulation of ligase activity (GO:0051351) | 3.02091944 |
| 60 | GTP biosynthetic process (GO:0006183) | 3.00964797 |
| 61 | ventricular cardiac muscle cell development (GO:0055015) | 2.99895303 |
| 62 | organ induction (GO:0001759) | 2.99372936 |
| 63 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 2.99273379 |
| 64 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 2.99273379 |
| 65 | positive regulation of endothelial cell differentiation (GO:0045603) | 2.95377169 |
| 66 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 2.93395483 |
| 67 | regulation of mitochondrial fission (GO:0090140) | 2.92433722 |
| 68 | retina homeostasis (GO:0001895) | 2.92061957 |
| 69 | positive regulation of protein complex disassembly (GO:0043243) | 2.91460648 |
| 70 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 2.90890876 |
| 71 | embryonic skeletal joint morphogenesis (GO:0060272) | 2.90724097 |
| 72 | negative regulation of metanephros development (GO:0072217) | 2.89869891 |
| 73 | guanosine-containing compound biosynthetic process (GO:1901070) | 2.89083272 |
| 74 | protein complex biogenesis (GO:0070271) | 2.87682831 |
| 75 | ribosome assembly (GO:0042255) | 2.85230103 |
| 76 | facial nerve structural organization (GO:0021612) | 2.84789700 |
| 77 | mitochondrial calcium ion homeostasis (GO:0051560) | 2.84684658 |
| 78 | barbed-end actin filament capping (GO:0051016) | 2.84418930 |
| 79 | myelin assembly (GO:0032288) | 2.81670744 |
| 80 | protein deneddylation (GO:0000338) | 2.80990528 |
| 81 | membrane raft organization (GO:0031579) | 2.80613221 |
| 82 | mesenchymal cell proliferation (GO:0010463) | 2.80119947 |
| 83 | DNA damage response, signal transduction by p53 class mediator (GO:0030330) | 2.77681176 |
| 84 | regulation of branching involved in prostate gland morphogenesis (GO:0060687) | 2.75496056 |
| 85 | regulation of ubiquitin-protein transferase activity (GO:0051438) | 2.75458438 |
| 86 | heart field specification (GO:0003128) | 2.74999465 |
| 87 | secondary heart field specification (GO:0003139) | 2.74999465 |
| 88 | lipopolysaccharide metabolic process (GO:0008653) | 2.74709524 |
| 89 | cell wall macromolecule catabolic process (GO:0016998) | 2.74426299 |
| 90 | mannosylation (GO:0097502) | 2.73352105 |
| 91 | regulation of cellular amine metabolic process (GO:0033238) | 2.72888132 |
| 92 | nucleoside transmembrane transport (GO:1901642) | 2.72713283 |
| 93 | negative regulation of mitochondrion organization (GO:0010823) | 2.72708324 |
| 94 | response to interferon-beta (GO:0035456) | 2.72600929 |
| 95 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 2.72363180 |
| 96 | ATP synthesis coupled proton transport (GO:0015986) | 2.72363180 |
| 97 | nucleotide transmembrane transport (GO:1901679) | 2.72110449 |
| 98 | endocardial cushion development (GO:0003197) | 2.71081667 |
| 99 | positive regulation of pseudopodium assembly (GO:0031274) | 2.70178571 |
| 100 | peptidyl-arginine omega-N-methylation (GO:0035247) | 2.67845705 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 4.09353361 |
| 2 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 3.66074597 |
| 3 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.62470339 |
| 4 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.59434235 |
| 5 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 3.51047752 |
| 6 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.39421470 |
| 7 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 3.39062786 |
| 8 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 3.12486275 |
| 9 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.80641013 |
| 10 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.79542868 |
| 11 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.78795224 |
| 12 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.74113228 |
| 13 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.65565726 |
| 14 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 2.54051335 |
| 15 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 2.51911173 |
| 16 | ATF3_23680149_ChIP-Seq_GBM1-GSC_Human | 2.49705656 |
| 17 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.45006062 |
| 18 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 2.36004028 |
| 19 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 2.29873594 |
| 20 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 2.28595933 |
| 21 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.27659847 |
| 22 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.23249023 |
| 23 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.21862661 |
| 24 | GABP_19822575_ChIP-Seq_HepG2_Human | 2.19760447 |
| 25 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 2.19618606 |
| 26 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.17959559 |
| 27 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 2.14287245 |
| 28 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 2.09160339 |
| 29 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 2.08533775 |
| 30 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 2.05030170 |
| 31 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.01968499 |
| 32 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.98099007 |
| 33 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.96587876 |
| 34 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.85529416 |
| 35 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.80863905 |
| 36 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.80564696 |
| 37 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.79510706 |
| 38 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.69622167 |
| 39 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.61640748 |
| 40 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.59707239 |
| 41 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.59233020 |
| 42 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.55439702 |
| 43 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.53287414 |
| 44 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.53055198 |
| 45 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.46915919 |
| 46 | JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.46601881 |
| 47 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.46451717 |
| 48 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 1.44017862 |
| 49 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 1.43370182 |
| 50 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.42040547 |
| 51 | CTCF_18555785_ChIP-Seq_MESCs_Mouse | 1.40985374 |
| 52 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.40613537 |
| 53 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.39884346 |
| 54 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.39472002 |
| 55 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.38756987 |
| 56 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.38717274 |
| 57 | SOX17_20123909_ChIP-Seq_XEN_Mouse | 1.36876377 |
| 58 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.35973354 |
| 59 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.35531380 |
| 60 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 1.35104666 |
| 61 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.32103201 |
| 62 | JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.31129070 |
| 63 | EOMES_21245162_ChIP-Seq_HESCs_Human | 1.30979883 |
| 64 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.30771641 |
| 65 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 1.27491671 |
| 66 | CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse | 1.25107412 |
| 67 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.24159976 |
| 68 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 1.24044697 |
| 69 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.23373819 |
| 70 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.23208438 |
| 71 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.22208912 |
| 72 | CSB_26484114_Chip-Seq_FIBROBLAST_Human | 1.21500964 |
| 73 | CBP_21632823_ChIP-Seq_H3396_Human | 1.21352079 |
| 74 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 1.20739436 |
| 75 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.19433340 |
| 76 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.18325173 |
| 77 | FOXP1_21924763_ChIP-Seq_HESCs_Human | 1.18097649 |
| 78 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 1.16142727 |
| 79 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.14661370 |
| 80 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.13591150 |
| 81 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.13426894 |
| 82 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.09692235 |
| 83 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.09587528 |
| 84 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.08128410 |
| 85 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.07820171 |
| 86 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.07145999 |
| 87 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.05578260 |
| 88 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.03909907 |
| 89 | TBX5_21415370_ChIP-Seq_HL-1_Mouse | 1.03862905 |
| 90 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.03044905 |
| 91 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 1.02123037 |
| 92 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.01464139 |
| 93 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.99091971 |
| 94 | SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 0.99086994 |
| 95 | ATF3_27146783_Chip-Seq_COLON_Human | 0.97991997 |
| 96 | TCFCP2L1_18555785_ChIP-Seq_MESCs_Mouse | 0.97960037 |
| 97 | SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 0.97603998 |
| 98 | SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 0.97603998 |
| 99 | NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 0.95317264 |
| 100 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.95212590 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0010030_abnormal_orbit_morphology | 5.45105284 |
| 2 | MP0005257_abnormal_intraocular_pressure | 4.16730721 |
| 3 | MP0003191_abnormal_cellular_cholesterol | 3.75242306 |
| 4 | MP0000749_muscle_degeneration | 3.73336969 |
| 5 | MP0003123_paternal_imprinting | 3.18515776 |
| 6 | MP0000751_myopathy | 2.91830839 |
| 7 | MP0008789_abnormal_olfactory_epithelium | 2.89928928 |
| 8 | MP0004272_abnormal_basement_membrane | 2.75253078 |
| 9 | MP0005367_renal/urinary_system_phenotyp | 2.50603281 |
| 10 | MP0000516_abnormal_urinary_system | 2.50603281 |
| 11 | MP0008775_abnormal_heart_ventricle | 2.46584621 |
| 12 | MP0001542_abnormal_bone_strength | 2.44319539 |
| 13 | MP0006054_spinal_hemorrhage | 2.35191104 |
| 14 | MP0008260_abnormal_autophagy | 2.33929098 |
| 15 | MP0000750_abnormal_muscle_regeneration | 2.26235517 |
| 16 | MP0001299_abnormal_eye_distance/ | 2.25066886 |
| 17 | MP0004147_increased_porphyrin_level | 2.24243324 |
| 18 | MP0009780_abnormal_chondrocyte_physiolo | 2.16148080 |
| 19 | MP0009840_abnormal_foam_cell | 2.13906335 |
| 20 | MP0002332_abnormal_exercise_endurance | 2.07701006 |
| 21 | MP0005670_abnormal_white_adipose | 2.03865677 |
| 22 | MP0005083_abnormal_biliary_tract | 1.99000738 |
| 23 | MP0003806_abnormal_nucleotide_metabolis | 1.96779114 |
| 24 | MP0003315_abnormal_perineum_morphology | 1.93920785 |
| 25 | MP0010368_abnormal_lymphatic_system | 1.86510459 |
| 26 | MP0005058_abnormal_lysosome_morphology | 1.85066097 |
| 27 | MP0004510_myositis | 1.82710677 |
| 28 | MP0003950_abnormal_plasma_membrane | 1.81230674 |
| 29 | MP0005499_abnormal_olfactory_system | 1.74702709 |
| 30 | MP0005394_taste/olfaction_phenotype | 1.74702709 |
| 31 | MP0002177_abnormal_outer_ear | 1.57310360 |
| 32 | MP0003880_abnormal_central_pattern | 1.55703757 |
| 33 | MP0000747_muscle_weakness | 1.53155640 |
| 34 | MP0005165_increased_susceptibility_to | 1.47228148 |
| 35 | MP0003786_premature_aging | 1.39443394 |
| 36 | MP0000762_abnormal_tongue_morphology | 1.36363820 |
| 37 | MP0009697_abnormal_copulation | 1.35533945 |
| 38 | MP0002102_abnormal_ear_morphology | 1.30702162 |
| 39 | MP0001727_abnormal_embryo_implantation | 1.28825487 |
| 40 | MP0000647_abnormal_sebaceous_gland | 1.26685111 |
| 41 | MP0005330_cardiomyopathy | 1.25552284 |
| 42 | MP0003186_abnormal_redox_activity | 1.25472356 |
| 43 | MP0000358_abnormal_cell_content/ | 1.25270521 |
| 44 | MP0005360_urolithiasis | 1.22877200 |
| 45 | MP0003566_abnormal_cell_adhesion | 1.21194164 |
| 46 | MP0002282_abnormal_trachea_morphology | 1.19194034 |
| 47 | MP0002653_abnormal_ependyma_morphology | 1.14082557 |
| 48 | MP0002938_white_spotting | 1.13852553 |
| 49 | MP0000343_altered_response_to | 1.12246832 |
| 50 | MP0001346_abnormal_lacrimal_gland | 1.11705731 |
| 51 | MP0008438_abnormal_cutaneous_collagen | 1.10292244 |
| 52 | MP0008932_abnormal_embryonic_tissue | 1.08209155 |
| 53 | MP0002269_muscular_atrophy | 1.03681213 |
| 54 | MP0003718_maternal_effect | 1.00117845 |
| 55 | MP0006035_abnormal_mitochondrial_morpho | 0.95196904 |
| 56 | MP0002972_abnormal_cardiac_muscle | 0.94947348 |
| 57 | MP0005197_abnormal_uvea_morphology | 0.90408220 |
| 58 | MP0006036_abnormal_mitochondrial_physio | 0.90222707 |
| 59 | MP0000372_irregular_coat_pigmentation | 0.89363141 |
| 60 | MP0005584_abnormal_enzyme/coenzyme_acti | 0.88499811 |
| 61 | MP0002295_abnormal_pulmonary_circulatio | 0.87859941 |
| 62 | MP0006276_abnormal_autonomic_nervous | 0.86872324 |
| 63 | MP0003077_abnormal_cell_cycle | 0.86143300 |
| 64 | MP0002106_abnormal_muscle_physiology | 0.85336563 |
| 65 | MP0001243_abnormal_dermal_layer | 0.85070301 |
| 66 | MP0008875_abnormal_xenobiotic_pharmacok | 0.84798897 |
| 67 | MP0000759_abnormal_skeletal_muscle | 0.82163979 |
| 68 | MP0003075_altered_response_to | 0.81217275 |
| 69 | MP0003938_abnormal_ear_development | 0.81181141 |
| 70 | MP0005620_abnormal_muscle_contractility | 0.80012480 |
| 71 | MP0001293_anophthalmia | 0.78629717 |
| 72 | MP0009046_muscle_twitch | 0.76797715 |
| 73 | MP0003121_genomic_imprinting | 0.76437753 |
| 74 | MP0002060_abnormal_skin_morphology | 0.76221557 |
| 75 | MP0005451_abnormal_body_composition | 0.75595553 |
| 76 | MP0002233_abnormal_nose_morphology | 0.74771419 |
| 77 | MP0000534_abnormal_ureter_morphology | 0.73296193 |
| 78 | MP0003942_abnormal_urinary_system | 0.70921324 |
| 79 | MP0000858_altered_metastatic_potential | 0.69458671 |
| 80 | MP0004087_abnormal_muscle_fiber | 0.69419264 |
| 81 | MP0005171_absent_coat_pigmentation | 0.68899862 |
| 82 | MP0003693_abnormal_embryo_hatching | 0.67779491 |
| 83 | MP0003638_abnormal_response/metabolism_ | 0.67342777 |
| 84 | MP0001905_abnormal_dopamine_level | 0.64641272 |
| 85 | MP0003656_abnormal_erythrocyte_physiolo | 0.64427081 |
| 86 | MP0005084_abnormal_gallbladder_morpholo | 0.63333306 |
| 87 | MP0004133_heterotaxia | 0.63269285 |
| 88 | MP0005369_muscle_phenotype | 0.63193534 |
| 89 | MP0000163_abnormal_cartilage_morphology | 0.61062504 |
| 90 | MP0001986_abnormal_taste_sensitivity | 0.60560141 |
| 91 | MP0003279_aneurysm | 0.59780964 |
| 92 | MP0002277_abnormal_respiratory_mucosa | 0.59712377 |
| 93 | MP0002127_abnormal_cardiovascular_syste | 0.59600616 |
| 94 | MP0000613_abnormal_salivary_gland | 0.59120944 |
| 95 | MP0005410_abnormal_fertilization | 0.57497263 |
| 96 | MP0004742_abnormal_vestibular_system | 0.55184367 |
| 97 | MP0005085_abnormal_gallbladder_physiolo | 0.54556784 |
| 98 | MP0001340_abnormal_eyelid_morphology | 0.54345643 |
| 99 | MP0002932_abnormal_joint_morphology | 0.54217174 |
| 100 | MP0003329_amyloid_beta_deposits | 0.53254703 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Delayed CNS myelination (HP:0002188) | 4.97123636 |
| 2 | Adrenal hypoplasia (HP:0000835) | 4.80195979 |
| 3 | Amyloidosis (HP:0011034) | 4.55990405 |
| 4 | Glucose intolerance (HP:0000833) | 3.97831726 |
| 5 | Microglossia (HP:0000171) | 3.85771766 |
| 6 | Hepatocellular necrosis (HP:0001404) | 3.79816135 |
| 7 | Upper limb muscle weakness (HP:0003484) | 3.56802212 |
| 8 | Reduced subcutaneous adipose tissue (HP:0003758) | 3.43892684 |
| 9 | Retinal dysplasia (HP:0007973) | 3.43242553 |
| 10 | Abnormal gallbladder physiology (HP:0012438) | 3.43188019 |
| 11 | Cholecystitis (HP:0001082) | 3.43188019 |
| 12 | Mitochondrial inheritance (HP:0001427) | 3.36455833 |
| 13 | Exercise-induced muscle cramps (HP:0003710) | 3.35495699 |
| 14 | Hepatic necrosis (HP:0002605) | 3.28887419 |
| 15 | Acute necrotizing encephalopathy (HP:0006965) | 3.10796461 |
| 16 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.07002591 |
| 17 | Increased serum pyruvate (HP:0003542) | 3.05356515 |
| 18 | Down-sloping shoulders (HP:0200021) | 3.02464610 |
| 19 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.95788362 |
| 20 | Abnormal protein glycosylation (HP:0012346) | 2.95788362 |
| 21 | Abnormal glycosylation (HP:0012345) | 2.95788362 |
| 22 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.95788362 |
| 23 | Type I transferrin isoform profile (HP:0003642) | 2.95777799 |
| 24 | Reduced antithrombin III activity (HP:0001976) | 2.92355329 |
| 25 | Abnormality of glycolysis (HP:0004366) | 2.91316825 |
| 26 | Increased CSF lactate (HP:0002490) | 2.85573400 |
| 27 | Severe muscular hypotonia (HP:0006829) | 2.83237203 |
| 28 | Microretrognathia (HP:0000308) | 2.77957311 |
| 29 | Abnormality of the musculature of the pelvis (HP:0001469) | 2.76733002 |
| 30 | Abnormality of the hip-girdle musculature (HP:0001445) | 2.76733002 |
| 31 | Shoulder girdle muscle weakness (HP:0003547) | 2.70607022 |
| 32 | Proximal placement of thumb (HP:0009623) | 2.64916904 |
| 33 | Limb-girdle muscle atrophy (HP:0003797) | 2.62740832 |
| 34 | Hypokinesia (HP:0002375) | 2.61850792 |
| 35 | Flat capital femoral epiphysis (HP:0003370) | 2.61253855 |
| 36 | Acute encephalopathy (HP:0006846) | 2.60079691 |
| 37 | Premature rupture of membranes (HP:0001788) | 2.59552909 |
| 38 | Pelvic girdle muscle weakness (HP:0003749) | 2.58301704 |
| 39 | Sclerocornea (HP:0000647) | 2.50954693 |
| 40 | Bifid uvula (HP:0000193) | 2.48232034 |
| 41 | Abnormal glucose tolerance (HP:0001952) | 2.47260854 |
| 42 | Short tibia (HP:0005736) | 2.45208752 |
| 43 | Exercise intolerance (HP:0003546) | 2.42900778 |
| 44 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 2.42227108 |
| 45 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.39740416 |
| 46 | Abnormality of alanine metabolism (HP:0010916) | 2.39740416 |
| 47 | Hyperalaninemia (HP:0003348) | 2.39740416 |
| 48 | Entropion (HP:0000621) | 2.39564430 |
| 49 | Median cleft lip (HP:0000161) | 2.36963396 |
| 50 | Supernumerary spleens (HP:0009799) | 2.35755675 |
| 51 | Progressive macrocephaly (HP:0004481) | 2.33535862 |
| 52 | Prolonged neonatal jaundice (HP:0006579) | 2.31778036 |
| 53 | Congenital primary aphakia (HP:0007707) | 2.28424146 |
| 54 | Deviation of the thumb (HP:0009603) | 2.25757433 |
| 55 | Increased serum lactate (HP:0002151) | 2.23151014 |
| 56 | Lactic acidosis (HP:0003128) | 2.20088210 |
| 57 | Difficulty climbing stairs (HP:0003551) | 2.19673323 |
| 58 | Renal Fanconi syndrome (HP:0001994) | 2.17099441 |
| 59 | Gait imbalance (HP:0002141) | 2.16192025 |
| 60 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 2.15631474 |
| 61 | Methylmalonic aciduria (HP:0012120) | 2.15504388 |
| 62 | Rough bone trabeculation (HP:0100670) | 2.15440767 |
| 63 | Hand muscle atrophy (HP:0009130) | 2.14163934 |
| 64 | CNS demyelination (HP:0007305) | 2.10071280 |
| 65 | Emotional lability (HP:0000712) | 2.09720536 |
| 66 | Preaxial hand polydactyly (HP:0001177) | 2.05678109 |
| 67 | Absent speech (HP:0001344) | 2.04921535 |
| 68 | Abnormality of liposaccharide metabolism (HP:0010968) | 2.04398088 |
| 69 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 2.04398088 |
| 70 | Abnormality of glycolipid metabolism (HP:0010969) | 2.04398088 |
| 71 | Delayed gross motor development (HP:0002194) | 2.02574923 |
| 72 | Medial flaring of the eyebrow (HP:0010747) | 2.01180736 |
| 73 | Nephrogenic diabetes insipidus (HP:0009806) | 1.99915199 |
| 74 | Sparse eyelashes (HP:0000653) | 1.99358147 |
| 75 | Postaxial foot polydactyly (HP:0001830) | 1.97316785 |
| 76 | Abnormality of the umbilical cord (HP:0010881) | 1.95730959 |
| 77 | Dental crowding (HP:0000678) | 1.95587362 |
| 78 | Insulin resistance (HP:0000855) | 1.95119720 |
| 79 | Cerebral edema (HP:0002181) | 1.94032529 |
| 80 | Abnormality of the sella turcica (HP:0002679) | 1.92546407 |
| 81 | Respiratory failure (HP:0002878) | 1.92242994 |
| 82 | Vacuolated lymphocytes (HP:0001922) | 1.87766318 |
| 83 | Vertebral compression fractures (HP:0002953) | 1.87578254 |
| 84 | Opisthotonus (HP:0002179) | 1.87137079 |
| 85 | Secondary amenorrhea (HP:0000869) | 1.86735634 |
| 86 | Short nail (HP:0001799) | 1.85586202 |
| 87 | X-linked dominant inheritance (HP:0001423) | 1.85346039 |
| 88 | Decreased subcutaneous fat (HP:0001002) | 1.84528495 |
| 89 | Joint hemorrhage (HP:0005261) | 1.81969252 |
| 90 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 1.81601325 |
| 91 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 1.81601325 |
| 92 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 1.81596130 |
| 93 | Renal hypoplasia (HP:0000089) | 1.81008238 |
| 94 | Myoglobinuria (HP:0002913) | 1.80666036 |
| 95 | Increased hepatocellular lipid droplets (HP:0006565) | 1.80651987 |
| 96 | Increased intramyocellular lipid droplets (HP:0012240) | 1.80351008 |
| 97 | Abnormalities of placenta or umbilical cord (HP:0001194) | 1.79954978 |
| 98 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 1.78979523 |
| 99 | Osteolytic defects of the hand bones (HP:0009699) | 1.78979523 |
| 100 | Hypoplastic pelvis (HP:0008839) | 1.77958702 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TESK2 | 5.33768614 |
| 2 | TESK1 | 5.07077310 |
| 3 | VRK2 | 4.85560172 |
| 4 | LIMK1 | 4.64367810 |
| 5 | NME2 | 4.48741789 |
| 6 | ARAF | 3.19007003 |
| 7 | EPHA2 | 2.67114528 |
| 8 | BCKDK | 2.61690967 |
| 9 | MAP2K7 | 2.43769262 |
| 10 | LMTK2 | 2.23010317 |
| 11 | BUB1 | 2.01080342 |
| 12 | DAPK1 | 1.96280850 |
| 13 | PIM2 | 1.92027993 |
| 14 | EPHB1 | 1.91326082 |
| 15 | CSNK1G3 | 1.80855014 |
| 16 | EPHA4 | 1.78643434 |
| 17 | MAP3K12 | 1.76167406 |
| 18 | KDR | 1.71461997 |
| 19 | CSNK1A1L | 1.69277749 |
| 20 | MOS | 1.63572821 |
| 21 | PHKG2 | 1.46960242 |
| 22 | PHKG1 | 1.46960242 |
| 23 | SRPK1 | 1.45921209 |
| 24 | MAPKAPK3 | 1.40296844 |
| 25 | PAK4 | 1.39719608 |
| 26 | CSNK1G2 | 1.38929762 |
| 27 | STK16 | 1.36398788 |
| 28 | MYLK | 1.36340217 |
| 29 | VRK1 | 1.35460296 |
| 30 | NUAK1 | 1.33341168 |
| 31 | CSNK1G1 | 1.29087673 |
| 32 | ABL2 | 1.20824053 |
| 33 | PDK2 | 1.19158703 |
| 34 | STK10 | 1.09008432 |
| 35 | PTK2B | 1.07135129 |
| 36 | ERBB3 | 1.03931024 |
| 37 | ILK | 1.00946581 |
| 38 | MST1R | 0.90633030 |
| 39 | PBK | 0.82701076 |
| 40 | AURKA | 0.81458183 |
| 41 | NEK1 | 0.80560021 |
| 42 | EPHB2 | 0.79796703 |
| 43 | PAK1 | 0.77751095 |
| 44 | INSRR | 0.73684593 |
| 45 | MUSK | 0.71935142 |
| 46 | CDK8 | 0.71785504 |
| 47 | DAPK3 | 0.71556831 |
| 48 | DAPK2 | 0.71237536 |
| 49 | GRK7 | 0.69261932 |
| 50 | MST4 | 0.68309850 |
| 51 | BRAF | 0.64136088 |
| 52 | TAOK2 | 0.63320773 |
| 53 | BRSK1 | 0.62708354 |
| 54 | FER | 0.59409626 |
| 55 | CDK14 | 0.58399198 |
| 56 | ERBB4 | 0.56393819 |
| 57 | MAP3K11 | 0.55353083 |
| 58 | TAF1 | 0.55127612 |
| 59 | BCR | 0.54077479 |
| 60 | ERN1 | 0.50904522 |
| 61 | CCNB1 | 0.50221649 |
| 62 | GRK5 | 0.50094050 |
| 63 | PLK1 | 0.50053761 |
| 64 | CDK18 | 0.46964737 |
| 65 | CDK15 | 0.46050319 |
| 66 | PLK3 | 0.45928958 |
| 67 | MAP4K2 | 0.45881264 |
| 68 | CDK7 | 0.44577592 |
| 69 | PLK2 | 0.43969142 |
| 70 | PINK1 | 0.42769882 |
| 71 | CDK11A | 0.42627830 |
| 72 | ADRBK1 | 0.38084001 |
| 73 | PTK2 | 0.37707781 |
| 74 | SCYL2 | 0.36516269 |
| 75 | DYRK2 | 0.35922307 |
| 76 | NME1 | 0.35830655 |
| 77 | RAF1 | 0.34799563 |
| 78 | EIF2AK3 | 0.33249766 |
| 79 | TGFBR2 | 0.32822328 |
| 80 | PRKCI | 0.32749475 |
| 81 | MAPKAPK2 | 0.30937199 |
| 82 | OBSCN | 0.29256641 |
| 83 | CAMK2G | 0.29232021 |
| 84 | BMX | 0.29119845 |
| 85 | STK38L | 0.29114968 |
| 86 | CSNK1A1 | 0.28999063 |
| 87 | WEE1 | 0.27960132 |
| 88 | BMPR1B | 0.27297708 |
| 89 | TIE1 | 0.26423653 |
| 90 | AURKB | 0.25251125 |
| 91 | PAK6 | 0.24882941 |
| 92 | CDK19 | 0.24200567 |
| 93 | MAP3K4 | 0.24110162 |
| 94 | TBK1 | 0.23783916 |
| 95 | CSNK2A2 | 0.21727944 |
| 96 | TLK1 | 0.21295758 |
| 97 | RPS6KA5 | 0.20813712 |
| 98 | TRIM28 | 0.17764621 |
| 99 | ZAK | 0.17501864 |
| 100 | PRKCE | 0.16888748 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 5.24692981 |
| 2 | Sulfur relay system_Homo sapiens_hsa04122 | 2.94298374 |
| 3 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.91528761 |
| 4 | Fatty acid elongation_Homo sapiens_hsa00062 | 2.76769355 |
| 5 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 2.71381456 |
| 6 | Parkinsons disease_Homo sapiens_hsa05012 | 2.61861405 |
| 7 | Steroid biosynthesis_Homo sapiens_hsa00100 | 2.43237022 |
| 8 | DNA replication_Homo sapiens_hsa03030 | 2.14508787 |
| 9 | Huntingtons disease_Homo sapiens_hsa05016 | 2.13175047 |
| 10 | Glutathione metabolism_Homo sapiens_hsa00480 | 2.09739602 |
| 11 | Galactose metabolism_Homo sapiens_hsa00052 | 2.02608295 |
| 12 | Alzheimers disease_Homo sapiens_hsa05010 | 1.99266200 |
| 13 | RNA polymerase_Homo sapiens_hsa03020 | 1.98735587 |
| 14 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 1.96171661 |
| 15 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.93763965 |
| 16 | Base excision repair_Homo sapiens_hsa03410 | 1.93386441 |
| 17 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.84822372 |
| 18 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 1.82282618 |
| 19 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 1.80896436 |
| 20 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.78600912 |
| 21 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.76010285 |
| 22 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 1.73976384 |
| 23 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 1.67381856 |
| 24 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.60786015 |
| 25 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.59129662 |
| 26 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.55279346 |
| 27 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.54900951 |
| 28 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.54151215 |
| 29 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.53945116 |
| 30 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.46488257 |
| 31 | Homologous recombination_Homo sapiens_hsa03440 | 1.43747126 |
| 32 | Mismatch repair_Homo sapiens_hsa03430 | 1.41702746 |
| 33 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.34510148 |
| 34 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 1.32079614 |
| 35 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.29609588 |
| 36 | Salivary secretion_Homo sapiens_hsa04970 | 1.29340689 |
| 37 | Carbon metabolism_Homo sapiens_hsa01200 | 1.25546484 |
| 38 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.22081396 |
| 39 | Ribosome_Homo sapiens_hsa03010 | 1.18893369 |
| 40 | Purine metabolism_Homo sapiens_hsa00230 | 1.12975740 |
| 41 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 1.08434492 |
| 42 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 1.07082111 |
| 43 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.04350822 |
| 44 | Protein export_Homo sapiens_hsa03060 | 1.02009972 |
| 45 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.98881420 |
| 46 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.94623161 |
| 47 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.91343325 |
| 48 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.87913333 |
| 49 | Metabolic pathways_Homo sapiens_hsa01100 | 0.85730692 |
| 50 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.85110886 |
| 51 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.85025008 |
| 52 | Peroxisome_Homo sapiens_hsa04146 | 0.84729121 |
| 53 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.83620318 |
| 54 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.82771232 |
| 55 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.80464060 |
| 56 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.78473838 |
| 57 | Other glycan degradation_Homo sapiens_hsa00511 | 0.77933601 |
| 58 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.76675063 |
| 59 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.72446760 |
| 60 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.70347273 |
| 61 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.68612716 |
| 62 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.68226790 |
| 63 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.66790590 |
| 64 | Lysosome_Homo sapiens_hsa04142 | 0.60520597 |
| 65 | Basal transcription factors_Homo sapiens_hsa03022 | 0.59220310 |
| 66 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.57671075 |
| 67 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.56153517 |
| 68 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.55603023 |
| 69 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.53747991 |
| 70 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.52997758 |
| 71 | Shigellosis_Homo sapiens_hsa05131 | 0.52198252 |
| 72 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.51993479 |
| 73 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.51416193 |
| 74 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.50338196 |
| 75 | RNA degradation_Homo sapiens_hsa03018 | 0.48203885 |
| 76 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.47770324 |
| 77 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.47131806 |
| 78 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.47112435 |
| 79 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.46418582 |
| 80 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.46203246 |
| 81 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.45049118 |
| 82 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.44498564 |
| 83 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.44450450 |
| 84 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.42946403 |
| 85 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.38591815 |
| 86 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.37966264 |
| 87 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.37064726 |
| 88 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.36453157 |
| 89 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.32973872 |
| 90 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.30347378 |
| 91 | Tight junction_Homo sapiens_hsa04530 | 0.29543725 |
| 92 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.28860286 |
| 93 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.25597198 |
| 94 | Spliceosome_Homo sapiens_hsa03040 | 0.25275054 |
| 95 | Cell cycle_Homo sapiens_hsa04110 | 0.23970525 |
| 96 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.23617923 |
| 97 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.23263639 |
| 98 | RNA transport_Homo sapiens_hsa03013 | 0.22200494 |
| 99 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.22162271 |
| 100 | Endocytosis_Homo sapiens_hsa04144 | 0.21026163 |

