

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | succinate metabolic process (GO:0006105) | 8.35776543 |
| 2 | cytoplasmic mRNA processing body assembly (GO:0033962) | 7.82939912 |
| 3 | peptidyl-arginine omega-N-methylation (GO:0035247) | 6.85962548 |
| 4 | peptidyl-arginine N-methylation (GO:0035246) | 6.37488411 |
| 5 | peptidyl-arginine methylation (GO:0018216) | 6.37488411 |
| 6 | tricarboxylic acid cycle (GO:0006099) | 6.08534192 |
| 7 | positive regulation of mitochondrial fission (GO:0090141) | 5.91140983 |
| 8 | positive regulation of phosphoprotein phosphatase activity (GO:0032516) | 5.90004899 |
| 9 | positive regulation of B cell differentiation (GO:0045579) | 5.79404423 |
| 10 | coenzyme catabolic process (GO:0009109) | 5.24135887 |
| 11 | spermatid development (GO:0007286) | 5.23211547 |
| 12 | histone arginine methylation (GO:0034969) | 5.12561430 |
| 13 | activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c (GO | 5.05612734 |
| 14 | regulation of mitochondrial depolarization (GO:0051900) | 5.03452627 |
| 15 | male sex determination (GO:0030238) | 4.91348554 |
| 16 | mitotic cell cycle arrest (GO:0071850) | 4.89308786 |
| 17 | ADP metabolic process (GO:0046031) | 4.73333413 |
| 18 | positive regulation of growth hormone secretion (GO:0060124) | 4.71984532 |
| 19 | nerve growth factor signaling pathway (GO:0038180) | 4.58878255 |
| 20 | sulfation (GO:0051923) | 4.42916523 |
| 21 | regulation of phosphoprotein phosphatase activity (GO:0043666) | 4.40774539 |
| 22 | negative regulation of activin receptor signaling pathway (GO:0032926) | 4.31990747 |
| 23 | glomerular visceral epithelial cell development (GO:0072015) | 4.31719142 |
| 24 | fibroblast migration (GO:0010761) | 4.29992207 |
| 25 | positive regulation of catecholamine secretion (GO:0033605) | 4.28624906 |
| 26 | relaxation of smooth muscle (GO:0044557) | 4.27073279 |
| 27 | regulation of mitochondrial fission (GO:0090140) | 4.09382203 |
| 28 | positive regulation of synaptic transmission, dopaminergic (GO:0032226) | 4.02397621 |
| 29 | positive regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060213) | 3.94962129 |
| 30 | regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060211) | 3.94962129 |
| 31 | cellular response to zinc ion (GO:0071294) | 3.83537371 |
| 32 | regulation of glycogen (starch) synthase activity (GO:2000465) | 3.83473871 |
| 33 | positive regulation of protein homooligomerization (GO:0032464) | 3.81748841 |
| 34 | peptidyl-arginine modification (GO:0018195) | 3.81148130 |
| 35 | regulation of phospholipase A2 activity (GO:0032429) | 3.79336294 |
| 36 | activation of protein kinase B activity (GO:0032148) | 3.77524564 |
| 37 | urinary tract smooth muscle contraction (GO:0014848) | 3.76196487 |
| 38 | glomerular epithelial cell development (GO:0072310) | 3.73106422 |
| 39 | regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510) | 3.69294056 |
| 40 | negative regulation of cell aging (GO:0090344) | 3.61963767 |
| 41 | negative regulation of cardiac muscle cell apoptotic process (GO:0010667) | 3.59909445 |
| 42 | granulocyte differentiation (GO:0030851) | 3.58408965 |
| 43 | lung-associated mesenchyme development (GO:0060484) | 3.56342082 |
| 44 | regulation of acyl-CoA biosynthetic process (GO:0050812) | 3.49968829 |
| 45 | negative regulation of DNA binding (GO:0043392) | 3.48217506 |
| 46 | mitochondrion degradation (GO:0000422) | 3.47107475 |
| 47 | regulation of protein homooligomerization (GO:0032462) | 3.46614607 |
| 48 | regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:1900151) | 3.42912519 |
| 49 | positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO | 3.42912519 |
| 50 | response to muscle activity (GO:0014850) | 3.41559527 |
| 51 | regulation of coenzyme metabolic process (GO:0051196) | 3.40087018 |
| 52 | regulation of cofactor metabolic process (GO:0051193) | 3.40087018 |
| 53 | peroxisome fission (GO:0016559) | 3.36512311 |
| 54 | oligosaccharide biosynthetic process (GO:0009312) | 3.28306983 |
| 55 | negative regulation of tumor necrosis factor-mediated signaling pathway (GO:0010804) | 3.27266933 |
| 56 | base-excision repair, AP site formation (GO:0006285) | 3.23690917 |
| 57 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 3.23027562 |
| 58 | negative regulation of epidermal cell differentiation (GO:0045605) | 3.21253420 |
| 59 | pyrimidine nucleotide catabolic process (GO:0006244) | 3.20645805 |
| 60 | protein K6-linked ubiquitination (GO:0085020) | 3.18730746 |
| 61 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 3.15607300 |
| 62 | DNA double-strand break processing (GO:0000729) | 3.07397006 |
| 63 | purine nucleoside diphosphate metabolic process (GO:0009135) | 3.06557841 |
| 64 | purine ribonucleoside diphosphate metabolic process (GO:0009179) | 3.06557841 |
| 65 | muscle cell cellular homeostasis (GO:0046716) | 3.05426425 |
| 66 | regulation of timing of cell differentiation (GO:0048505) | 3.05405583 |
| 67 | neuromuscular synaptic transmission (GO:0007274) | 3.01488499 |
| 68 | regulation of membrane depolarization (GO:0003254) | 3.00405099 |
| 69 | muscle organ morphogenesis (GO:0048644) | 2.99128920 |
| 70 | positive regulation of protein kinase C signaling (GO:0090037) | 2.98340156 |
| 71 | negative regulation of transcription regulatory region DNA binding (GO:2000678) | 2.95857982 |
| 72 | DNA integration (GO:0015074) | 2.95261907 |
| 73 | neuronal action potential (GO:0019228) | 2.94037863 |
| 74 | sex determination (GO:0007530) | 2.92196527 |
| 75 | motile cilium assembly (GO:0044458) | 2.91139161 |
| 76 | negative regulation of smooth muscle contraction (GO:0045986) | 2.88836002 |
| 77 | ER overload response (GO:0006983) | 2.88172720 |
| 78 | extrinsic apoptotic signaling pathway via death domain receptors (GO:0008625) | 2.88024178 |
| 79 | methionine biosynthetic process (GO:0009086) | 2.85367945 |
| 80 | positive regulation of receptor internalization (GO:0002092) | 2.85262788 |
| 81 | nucleotide phosphorylation (GO:0046939) | 2.81755334 |
| 82 | positive regulation of phosphatase activity (GO:0010922) | 2.77534132 |
| 83 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 2.76359199 |
| 84 | cofactor catabolic process (GO:0051187) | 2.76305366 |
| 85 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 2.75908978 |
| 86 | AMP metabolic process (GO:0046033) | 2.75741574 |
| 87 | protein import into peroxisome matrix (GO:0016558) | 2.75193802 |
| 88 | omega-hydroxylase P450 pathway (GO:0097267) | 2.74633380 |
| 89 | embryonic digestive tract development (GO:0048566) | 2.72782814 |
| 90 | negative regulation of organelle assembly (GO:1902116) | 2.72762651 |
| 91 | negative regulation of lipase activity (GO:0060192) | 2.71626664 |
| 92 | regulation of autophagic vacuole assembly (GO:2000785) | 2.70916202 |
| 93 | regulation of development, heterochronic (GO:0040034) | 2.68851389 |
| 94 | positive regulation of icosanoid secretion (GO:0032305) | 2.68530475 |
| 95 | behavioral response to nicotine (GO:0035095) | 2.67490458 |
| 96 | peristalsis (GO:0030432) | 2.67472452 |
| 97 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 2.67344431 |
| 98 | regulation of B cell differentiation (GO:0045577) | 2.65879813 |
| 99 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan (GO:0019800) | 2.64580122 |
| 100 | diacylglycerol metabolic process (GO:0046339) | 2.64466526 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 7.43409815 |
| 2 | GATA1_22025678_ChIP-Seq_K562_Human | 5.18381293 |
| 3 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 4.55996839 |
| 4 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 4.48343065 |
| 5 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 4.29380843 |
| 6 | GBX2_23144817_ChIP-Seq_PC3_Human | 4.01192927 |
| 7 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.77356381 |
| 8 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 3.36585410 |
| 9 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 3.13332278 |
| 10 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 2.80215228 |
| 11 | VDR_22108803_ChIP-Seq_LS180_Human | 2.76957929 |
| 12 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.45405052 |
| 13 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.28759802 |
| 14 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 2.17293721 |
| 15 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 2.08870425 |
| 16 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.95157830 |
| 17 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.95157830 |
| 18 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.92261921 |
| 19 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.91733526 |
| 20 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.90997493 |
| 21 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.87946895 |
| 22 | ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.74288488 |
| 23 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.62421640 |
| 24 | P300_19829295_ChIP-Seq_ESCs_Human | 1.59287427 |
| 25 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.57453669 |
| 26 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.57453669 |
| 27 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.55221622 |
| 28 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.52669430 |
| 29 | ERA_21632823_ChIP-Seq_H3396_Human | 1.50175805 |
| 30 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.49442262 |
| 31 | RXR_22108803_ChIP-Seq_LS180_Human | 1.48968571 |
| 32 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.47204006 |
| 33 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.44674165 |
| 34 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.43911313 |
| 35 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.38098373 |
| 36 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 1.31872828 |
| 37 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.27318984 |
| 38 | WDR5_24793694_ChIP-Seq_LNCAP_Human | 1.27271681 |
| 39 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.24946761 |
| 40 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.23046491 |
| 41 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.21165525 |
| 42 | NCOR_22424771_ChIP-Seq_293T_Human | 1.20834089 |
| 43 | RAC3_21632823_ChIP-Seq_H3396_Human | 1.18768116 |
| 44 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.18278073 |
| 45 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 1.16208264 |
| 46 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.15988994 |
| 47 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.15454080 |
| 48 | MYC_19829295_ChIP-Seq_ESCs_Human | 1.15260277 |
| 49 | TCF4_23295773_ChIP-Seq_U87_Human | 1.14860978 |
| 50 | OCT4_20526341_ChIP-Seq_ESCs_Human | 1.13682285 |
| 51 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.12020671 |
| 52 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.09704384 |
| 53 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.09645249 |
| 54 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.09024543 |
| 55 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.08145806 |
| 56 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.06813303 |
| 57 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.05319314 |
| 58 | E2F1_17053090_ChIP-ChIP_MCF-7_Human | 1.04100810 |
| 59 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.03716598 |
| 60 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 1.03545987 |
| 61 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.00936060 |
| 62 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.00043422 |
| 63 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 0.98903183 |
| 64 | CJUN_26792858_Chip-Seq_BT549_Human | 0.98805367 |
| 65 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 0.98367530 |
| 66 | RAD21_21589869_ChIP-Seq_MESCs_Mouse | 0.97016188 |
| 67 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 0.95840713 |
| 68 | ZNF263_19887448_ChIP-Seq_K562_Human | 0.94125541 |
| 69 | NFI_21473784_ChIP-Seq_ESCs_Mouse | 0.93838424 |
| 70 | TBL1_22424771_ChIP-Seq_293T_Human | 0.92924974 |
| 71 | SETDB1_19884257_ChIP-Seq_MESCs_Mouse | 0.92312163 |
| 72 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 0.91872907 |
| 73 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.91855682 |
| 74 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.88898403 |
| 75 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.87681981 |
| 76 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.87620210 |
| 77 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.87444647 |
| 78 | MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 0.85651491 |
| 79 | NFYB_21822215_ChIP-Seq_K562_Human | 0.84868913 |
| 80 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 0.84126085 |
| 81 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 0.84002335 |
| 82 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 0.83819835 |
| 83 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 0.83819835 |
| 84 | TCF4_22108803_ChIP-Seq_LS180_Human | 0.83262336 |
| 85 | GF1B_26923725_Chip-Seq_HPCs_Mouse | 0.82646017 |
| 86 | ELF5_23300383_ChIP-Seq_T47D_Human | 0.82093156 |
| 87 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.80756771 |
| 88 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 0.80116790 |
| 89 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.79807410 |
| 90 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 0.79518321 |
| 91 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 0.79329297 |
| 92 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.78804020 |
| 93 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.77966672 |
| 94 | MYC_18940864_ChIP-ChIP_HL60_Human | 0.76528821 |
| 95 | CBP_21632823_ChIP-Seq_H3396_Human | 0.76377516 |
| 96 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 0.76353325 |
| 97 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 0.75159673 |
| 98 | STAT1_17558387_ChIP-Seq_HELA_Human | 0.75064352 |
| 99 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 0.74521628 |
| 100 | AR_25329375_ChIP-Seq_VCAP_Human | 0.74476734 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0000566_synostosis | 6.32492040 |
| 2 | MP0003806_abnormal_nucleotide_metabolis | 3.82605880 |
| 3 | MP0002132_abnormal_respiratory_system | 3.59838746 |
| 4 | MP0000749_muscle_degeneration | 3.23443322 |
| 5 | MP0003136_yellow_coat_color | 2.78867723 |
| 6 | MP0002102_abnormal_ear_morphology | 2.78692321 |
| 7 | MP0002822_catalepsy | 2.66326972 |
| 8 | MP0005365_abnormal_bile_salt | 2.62615705 |
| 9 | MP0009697_abnormal_copulation | 2.40445410 |
| 10 | MP0002837_dystrophic_cardiac_calcinosis | 2.38101931 |
| 11 | MP0001529_abnormal_vocalization | 2.37159055 |
| 12 | MP0000747_muscle_weakness | 2.29289669 |
| 13 | MP0003315_abnormal_perineum_morphology | 2.28908429 |
| 14 | MP0009780_abnormal_chondrocyte_physiolo | 2.26867834 |
| 15 | MP0003868_abnormal_feces_composition | 2.20197523 |
| 16 | MP0009840_abnormal_foam_cell | 2.19573599 |
| 17 | MP0006036_abnormal_mitochondrial_physio | 2.13227567 |
| 18 | MP0005646_abnormal_pituitary_gland | 2.13087496 |
| 19 | MP0008877_abnormal_DNA_methylation | 2.12053641 |
| 20 | MP0010386_abnormal_urinary_bladder | 2.06725672 |
| 21 | MP0000751_myopathy | 2.00810954 |
| 22 | MP0005085_abnormal_gallbladder_physiolo | 1.96443525 |
| 23 | MP0005394_taste/olfaction_phenotype | 1.96225921 |
| 24 | MP0005499_abnormal_olfactory_system | 1.96225921 |
| 25 | MP0002160_abnormal_reproductive_system | 1.81502785 |
| 26 | MP0005410_abnormal_fertilization | 1.76466808 |
| 27 | MP0009046_muscle_twitch | 1.74003688 |
| 28 | MP0008789_abnormal_olfactory_epithelium | 1.72352954 |
| 29 | MP0005058_abnormal_lysosome_morphology | 1.70402913 |
| 30 | MP0010368_abnormal_lymphatic_system | 1.67277483 |
| 31 | MP0000538_abnormal_urinary_bladder | 1.58532849 |
| 32 | MP0004084_abnormal_cardiac_muscle | 1.56974565 |
| 33 | MP0005171_absent_coat_pigmentation | 1.56045865 |
| 34 | MP0002751_abnormal_autonomic_nervous | 1.52701782 |
| 35 | MP0001299_abnormal_eye_distance/ | 1.52071433 |
| 36 | MP0001485_abnormal_pinna_reflex | 1.43607641 |
| 37 | MP0008004_abnormal_stomach_pH | 1.43513540 |
| 38 | MP0006072_abnormal_retinal_apoptosis | 1.32342718 |
| 39 | MP0000049_abnormal_middle_ear | 1.31935147 |
| 40 | MP0003567_abnormal_fetal_cardiomyocyte | 1.31414896 |
| 41 | MP0003385_abnormal_body_wall | 1.29891982 |
| 42 | MP0003787_abnormal_imprinting | 1.29623263 |
| 43 | MP0005253_abnormal_eye_physiology | 1.29074122 |
| 44 | MP0001502_abnormal_circadian_rhythm | 1.19633944 |
| 45 | MP0001929_abnormal_gametogenesis | 1.18526937 |
| 46 | MP0004484_altered_response_of | 1.18048818 |
| 47 | MP0000537_abnormal_urethra_morphology | 1.17714774 |
| 48 | MP0004272_abnormal_basement_membrane | 1.15972847 |
| 49 | MP0005330_cardiomyopathy | 1.06993205 |
| 50 | MP0002127_abnormal_cardiovascular_syste | 1.06910593 |
| 51 | MP0000681_abnormal_thyroid_gland | 1.05667213 |
| 52 | MP0001664_abnormal_digestion | 1.04902045 |
| 53 | MP0001544_abnormal_cardiovascular_syste | 1.00933872 |
| 54 | MP0005385_cardiovascular_system_phenoty | 1.00933872 |
| 55 | MP0005551_abnormal_eye_electrophysiolog | 1.00185756 |
| 56 | MP0002233_abnormal_nose_morphology | 0.98213470 |
| 57 | MP0001501_abnormal_sleep_pattern | 0.96380384 |
| 58 | MP0001145_abnormal_male_reproductive | 0.95457374 |
| 59 | MP0002249_abnormal_larynx_morphology | 0.94849498 |
| 60 | MP0001968_abnormal_touch/_nociception | 0.93940003 |
| 61 | MP0003698_abnormal_male_reproductive | 0.92761294 |
| 62 | MP0001486_abnormal_startle_reflex | 0.91775851 |
| 63 | MP0006035_abnormal_mitochondrial_morpho | 0.91655555 |
| 64 | MP0002108_abnormal_muscle_morphology | 0.90516411 |
| 65 | MP0003942_abnormal_urinary_system | 0.89994467 |
| 66 | MP0002210_abnormal_sex_determination | 0.87584561 |
| 67 | MP0000631_abnormal_neuroendocrine_gland | 0.87370279 |
| 68 | MP0003936_abnormal_reproductive_system | 0.84043368 |
| 69 | MP0005360_urolithiasis | 0.83330638 |
| 70 | MP0005174_abnormal_tail_pigmentation | 0.82885007 |
| 71 | MP0005187_abnormal_penis_morphology | 0.82446695 |
| 72 | MP0000653_abnormal_sex_gland | 0.81872287 |
| 73 | MP0001661_extended_life_span | 0.81592347 |
| 74 | MP0004924_abnormal_behavior | 0.81364406 |
| 75 | MP0005386_behavior/neurological_phenoty | 0.81364406 |
| 76 | MP0003122_maternal_imprinting | 0.80710624 |
| 77 | MP0001270_distended_abdomen | 0.80509377 |
| 78 | MP0000343_altered_response_to | 0.80492418 |
| 79 | MP0001905_abnormal_dopamine_level | 0.78889623 |
| 80 | MP0004782_abnormal_surfactant_physiolog | 0.78072582 |
| 81 | MP0003755_abnormal_palate_morphology | 0.75604727 |
| 82 | MP0004036_abnormal_muscle_relaxation | 0.74435395 |
| 83 | MP0002932_abnormal_joint_morphology | 0.72910236 |
| 84 | MP0005248_abnormal_Harderian_gland | 0.71470399 |
| 85 | MP0000372_irregular_coat_pigmentation | 0.70373499 |
| 86 | MP0003938_abnormal_ear_development | 0.70364754 |
| 87 | MP0005389_reproductive_system_phenotype | 0.68825827 |
| 88 | MP0005620_abnormal_muscle_contractility | 0.67898492 |
| 89 | MP0002064_seizures | 0.66715565 |
| 90 | MP0000759_abnormal_skeletal_muscle | 0.66514606 |
| 91 | MP0005391_vision/eye_phenotype | 0.65071877 |
| 92 | MP0001756_abnormal_urination | 0.64376634 |
| 93 | MP0003880_abnormal_central_pattern | 0.64105304 |
| 94 | MP0002111_abnormal_tail_morphology | 0.64100921 |
| 95 | MP0002572_abnormal_emotion/affect_behav | 0.63926510 |
| 96 | MP0002269_muscular_atrophy | 0.63855904 |
| 97 | MP0009745_abnormal_behavioral_response | 0.63111355 |
| 98 | MP0001764_abnormal_homeostasis | 0.62981255 |
| 99 | MP0001984_abnormal_olfaction | 0.60866541 |
| 100 | MP0009764_decreased_sensitivity_to | 0.60675706 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Methylmalonic aciduria (HP:0012120) | 7.70467838 |
| 2 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 5.98348359 |
| 3 | Unsteady gait (HP:0002317) | 5.14913572 |
| 4 | Humeroradial synostosis (HP:0003041) | 4.50046984 |
| 5 | Synostosis involving the elbow (HP:0003938) | 4.50046984 |
| 6 | Reduced antithrombin III activity (HP:0001976) | 4.16233938 |
| 7 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 3.63716110 |
| 8 | Dicarboxylic aciduria (HP:0003215) | 3.63716110 |
| 9 | Abnormality of the columella (HP:0009929) | 3.45167739 |
| 10 | Decreased central vision (HP:0007663) | 3.42169109 |
| 11 | Abnormal rod and cone electroretinograms (HP:0008323) | 3.31135853 |
| 12 | Clumsiness (HP:0002312) | 3.28714137 |
| 13 | Amblyopia (HP:0000646) | 3.22309266 |
| 14 | Pheochromocytoma (HP:0002666) | 3.03267250 |
| 15 | Retinal dysplasia (HP:0007973) | 2.94723835 |
| 16 | Type II lissencephaly (HP:0007260) | 2.84219073 |
| 17 | Abnormality of long-chain fatty-acid metabolism (HP:0010964) | 2.83777835 |
| 18 | Short middle phalanx of the 5th finger (HP:0004220) | 2.80622776 |
| 19 | Brushfield spots (HP:0001088) | 2.77036731 |
| 20 | Inability to walk (HP:0002540) | 2.75668375 |
| 21 | Nonimmune hydrops fetalis (HP:0001790) | 2.75552770 |
| 22 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.72558948 |
| 23 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.72558948 |
| 24 | Abnormal protein glycosylation (HP:0012346) | 2.72558948 |
| 25 | Abnormal glycosylation (HP:0012345) | 2.72558948 |
| 26 | Pancreatic cysts (HP:0001737) | 2.68657278 |
| 27 | Attenuation of retinal blood vessels (HP:0007843) | 2.66838457 |
| 28 | Capillary hemangiomas (HP:0005306) | 2.66167714 |
| 29 | Cubitus valgus (HP:0002967) | 2.65595116 |
| 30 | Aplasia/Hypoplasia of the frontal sinuses (HP:0009119) | 2.63263122 |
| 31 | Type I transferrin isoform profile (HP:0003642) | 2.62070707 |
| 32 | Facial hemangioma (HP:0000329) | 2.60211307 |
| 33 | Ketosis (HP:0001946) | 2.60104966 |
| 34 | Protruding tongue (HP:0010808) | 2.55460316 |
| 35 | Enlarged kidneys (HP:0000105) | 2.53239644 |
| 36 | Neuroendocrine neoplasm (HP:0100634) | 2.46244130 |
| 37 | Hypoplasia of the thymus (HP:0000778) | 2.45266459 |
| 38 | Short 5th finger (HP:0009237) | 2.39636644 |
| 39 | Conjunctival hamartoma (HP:0100780) | 2.38962658 |
| 40 | Gaze-evoked nystagmus (HP:0000640) | 2.38342269 |
| 41 | Atonic seizures (HP:0010819) | 2.37788950 |
| 42 | Turricephaly (HP:0000262) | 2.36035885 |
| 43 | Hamartoma of the eye (HP:0010568) | 2.35557489 |
| 44 | Abnormality of the intrinsic pathway (HP:0010989) | 2.34833665 |
| 45 | Meningioma (HP:0002858) | 2.34165013 |
| 46 | Large for gestational age (HP:0001520) | 2.33020049 |
| 47 | Hypophosphatemia (HP:0002148) | 2.32843223 |
| 48 | Optic nerve hypoplasia (HP:0000609) | 2.32149344 |
| 49 | Symphalangism affecting the phalanges of the hand (HP:0009773) | 2.26490242 |
| 50 | Abnormality of the shoulder girdle musculature (HP:0001435) | 2.22886079 |
| 51 | Aplasia/Hypoplasia of the 5th finger (HP:0006262) | 2.19705262 |
| 52 | Benign neoplasm of the central nervous system (HP:0100835) | 2.19607693 |
| 53 | Febrile seizures (HP:0002373) | 2.17374074 |
| 54 | Cerebral hemorrhage (HP:0001342) | 2.14634539 |
| 55 | Cerebral hypomyelination (HP:0006808) | 2.10466120 |
| 56 | Chronic hepatic failure (HP:0100626) | 2.09911949 |
| 57 | Delayed gross motor development (HP:0002194) | 2.06272057 |
| 58 | Absent speech (HP:0001344) | 2.04766538 |
| 59 | Scapular winging (HP:0003691) | 2.02810139 |
| 60 | Hyperventilation (HP:0002883) | 12.4918869 |
| 61 | Aplasia/Hypoplasia involving the sinuses (HP:0009120) | 1.99646929 |
| 62 | Pancreatic fibrosis (HP:0100732) | 1.98773358 |
| 63 | Respiratory failure (HP:0002878) | 1.96837764 |
| 64 | Cerebellar dysplasia (HP:0007033) | 1.96731648 |
| 65 | Abnormality of the frontal sinuses (HP:0002687) | 1.96545238 |
| 66 | Pancreatic islet-cell hyperplasia (HP:0004510) | 1.94860043 |
| 67 | Intellectual disability, severe (HP:0010864) | 1.94293811 |
| 68 | True hermaphroditism (HP:0010459) | 1.93950456 |
| 69 | Hyporeflexia of lower limbs (HP:0002600) | 1.92825101 |
| 70 | Abnormal pancreas size (HP:0012094) | 1.92586313 |
| 71 | Clitoromegaly (HP:0000057) | 1.92190711 |
| 72 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 1.91530352 |
| 73 | Retinal atrophy (HP:0001105) | 1.88983940 |
| 74 | Bile duct proliferation (HP:0001408) | 1.88451806 |
| 75 | Abnormal biliary tract physiology (HP:0012439) | 1.88451806 |
| 76 | Exercise-induced muscle cramps (HP:0003710) | 1.86104412 |
| 77 | Bone cyst (HP:0012062) | 1.83839934 |
| 78 | Abnormal respiratory motile cilium physiology (HP:0012261) | 1.81826717 |
| 79 | High anterior hairline (HP:0009890) | 1.79793731 |
| 80 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 1.79780128 |
| 81 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 1.79780128 |
| 82 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 1.78466647 |
| 83 | Cystic liver disease (HP:0006706) | 1.77441891 |
| 84 | Progressive inability to walk (HP:0002505) | 1.75806685 |
| 85 | Abnormality of the pancreatic islet cells (HP:0006476) | 1.75478223 |
| 86 | Abnormality of endocrine pancreas physiology (HP:0012093) | 1.75478223 |
| 87 | Facial diplegia (HP:0001349) | 1.75398053 |
| 88 | Aplasia/Hypoplasia of the middle phalanges of the hand (HP:0009843) | 1.72869362 |
| 89 | Eosinophilia (HP:0001880) | 1.71653846 |
| 90 | Long foot (HP:0001833) | 1.71292294 |
| 91 | Supernumerary spleens (HP:0009799) | 1.67071760 |
| 92 | Hypoplastic iliac wings (HP:0002866) | 1.66458324 |
| 93 | Acanthocytosis (HP:0001927) | 1.66210101 |
| 94 | Upper limb muscle weakness (HP:0003484) | 1.64172362 |
| 95 | Congenital sensorineural hearing impairment (HP:0008527) | 1.62634380 |
| 96 | Abnormality of lateral ventricle (HP:0030047) | 1.62583405 |
| 97 | Reticulocytosis (HP:0001923) | 1.61115959 |
| 98 | Tetraparesis (HP:0002273) | 1.60967051 |
| 99 | Absent/shortened dynein arms (HP:0200106) | 1.58779561 |
| 100 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 1.58779561 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | PINK1 | 6.49141456 |
| 2 | CDK8 | 5.19453940 |
| 3 | MARK3 | 3.82242455 |
| 4 | CSNK1A1L | 2.98875563 |
| 5 | MAP3K4 | 2.90743358 |
| 6 | CSNK1G3 | 2.74942671 |
| 7 | OBSCN | 2.72241539 |
| 8 | FRK | 2.54779083 |
| 9 | CSNK1G2 | 2.28441441 |
| 10 | LATS1 | 2.24974682 |
| 11 | CSNK1G1 | 2.17180915 |
| 12 | NEK2 | 2.16032210 |
| 13 | BCKDK | 2.15877132 |
| 14 | DYRK3 | 2.08373322 |
| 15 | MAP2K7 | 2.03177983 |
| 16 | MOS | 2.01966649 |
| 17 | MYLK | 1.91788827 |
| 18 | PDK2 | 1.83891848 |
| 19 | EIF2AK3 | 1.68736744 |
| 20 | STK38L | 1.66745575 |
| 21 | ZAK | 1.61401793 |
| 22 | MAPK15 | 1.57258076 |
| 23 | CLK1 | 1.53401371 |
| 24 | BMPR1B | 1.48496336 |
| 25 | GRK5 | 1.42978198 |
| 26 | EPHB1 | 1.36700734 |
| 27 | DYRK1B | 1.36673982 |
| 28 | CASK | 1.28018512 |
| 29 | GRK7 | 1.18875816 |
| 30 | SGK223 | 1.15530741 |
| 31 | SGK494 | 1.15530741 |
| 32 | TIE1 | 1.14625384 |
| 33 | MAP3K7 | 1.13866996 |
| 34 | TGFBR2 | 1.12103295 |
| 35 | DYRK2 | 1.10914556 |
| 36 | MARK1 | 1.04294307 |
| 37 | CDK3 | 0.96047845 |
| 38 | GRK1 | 0.93774025 |
| 39 | RPS6KA5 | 0.91722124 |
| 40 | KDR | 0.89776432 |
| 41 | ADRBK2 | 0.86610897 |
| 42 | CDK19 | 0.78625253 |
| 43 | SGK2 | 0.77850251 |
| 44 | PAK3 | 0.77069739 |
| 45 | BRD4 | 0.76665650 |
| 46 | MAPK13 | 0.74788395 |
| 47 | TGFBR1 | 0.74788382 |
| 48 | PKN2 | 0.71667290 |
| 49 | STK38 | 0.70199652 |
| 50 | RPS6KA4 | 0.69912895 |
| 51 | FGFR2 | 0.68285574 |
| 52 | MAPK12 | 0.64504160 |
| 53 | PRKCQ | 0.59588169 |
| 54 | TLK1 | 0.58455406 |
| 55 | MAPKAPK5 | 0.57414893 |
| 56 | NME2 | 0.57081088 |
| 57 | RPS6KB1 | 0.56779181 |
| 58 | PIK3CA | 0.54528422 |
| 59 | CSNK1A1 | 0.53673485 |
| 60 | MAP3K10 | 0.51034150 |
| 61 | PAK2 | 0.49375201 |
| 62 | CSNK1D | 0.48690217 |
| 63 | CAMK1 | 0.48372106 |
| 64 | CAMK4 | 0.47606787 |
| 65 | ROCK1 | 0.46535086 |
| 66 | PKN1 | 0.44675100 |
| 67 | PAK1 | 0.44447274 |
| 68 | PRKCI | 0.41142948 |
| 69 | MELK | 0.33950341 |
| 70 | CDK14 | 0.33841248 |
| 71 | SGK3 | 0.33507757 |
| 72 | ADRBK1 | 0.32385261 |
| 73 | CDK12 | 0.32156411 |
| 74 | LATS2 | 0.31181645 |
| 75 | ACVR1B | 0.30828683 |
| 76 | NUAK1 | 0.29687217 |
| 77 | BCR | 0.29571433 |
| 78 | STK3 | 0.29545351 |
| 79 | DAPK3 | 0.28475810 |
| 80 | MAPKAPK3 | 0.28284789 |
| 81 | RPS6KA6 | 0.28284231 |
| 82 | STK4 | 0.26897585 |
| 83 | PDK1 | 0.26321340 |
| 84 | ILK | 0.26207983 |
| 85 | BTK | 0.26063211 |
| 86 | CDK5 | 0.25848036 |
| 87 | PRKG1 | 0.24458547 |
| 88 | STK11 | 0.23612776 |
| 89 | EGFR | 0.23381168 |
| 90 | VRK1 | 0.22782245 |
| 91 | CAMK2D | 0.21567025 |
| 92 | PRKG2 | 0.21230252 |
| 93 | RET | 0.20648056 |
| 94 | MAP3K1 | 0.20552940 |
| 95 | MUSK | 0.20315039 |
| 96 | PTK2B | 0.20185711 |
| 97 | PRKCG | 0.19232526 |
| 98 | MAP3K13 | 0.19198086 |
| 99 | PDPK1 | 0.18375738 |
| 100 | AKT3 | 0.16442217 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 6.72690989 |
| 2 | Propanoate metabolism_Homo sapiens_hsa00640 | 6.01577262 |
| 3 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 2.57422122 |
| 4 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 2.40612528 |
| 5 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 2.39384135 |
| 6 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 2.35975486 |
| 7 | Olfactory transduction_Homo sapiens_hsa04740 | 2.32809835 |
| 8 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 2.24163692 |
| 9 | Nitrogen metabolism_Homo sapiens_hsa00910 | 2.06722471 |
| 10 | Carbon metabolism_Homo sapiens_hsa01200 | 1.91179171 |
| 11 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.89201256 |
| 12 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.77219209 |
| 13 | RNA degradation_Homo sapiens_hsa03018 | 1.71563948 |
| 14 | Phototransduction_Homo sapiens_hsa04744 | 1.60131039 |
| 15 | Proteasome_Homo sapiens_hsa03050 | 1.58571652 |
| 16 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.57152672 |
| 17 | Basal transcription factors_Homo sapiens_hsa03022 | 1.41861519 |
| 18 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.37622286 |
| 19 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 1.29515825 |
| 20 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.29446159 |
| 21 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 1.23694556 |
| 22 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 1.20126530 |
| 23 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 1.18605094 |
| 24 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.17759140 |
| 25 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 1.14206556 |
| 26 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.12372942 |
| 27 | ABC transporters_Homo sapiens_hsa02010 | 1.12284462 |
| 28 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.11567119 |
| 29 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.11428758 |
| 30 | Peroxisome_Homo sapiens_hsa04146 | 1.10210283 |
| 31 | Circadian rhythm_Homo sapiens_hsa04710 | 1.06217584 |
| 32 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 1.02340128 |
| 33 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 1.00686868 |
| 34 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.98429078 |
| 35 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.94538933 |
| 36 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.93608229 |
| 37 | RNA polymerase_Homo sapiens_hsa03020 | 0.89675081 |
| 38 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.89268635 |
| 39 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.87385506 |
| 40 | Mineral absorption_Homo sapiens_hsa04978 | 0.84769538 |
| 41 | Retinol metabolism_Homo sapiens_hsa00830 | 0.83109597 |
| 42 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.80281734 |
| 43 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.80258841 |
| 44 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.79988277 |
| 45 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.79303657 |
| 46 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.78613373 |
| 47 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.75539666 |
| 48 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.75493828 |
| 49 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.75221433 |
| 50 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.74737890 |
| 51 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.74453899 |
| 52 | Purine metabolism_Homo sapiens_hsa00230 | 0.74300491 |
| 53 | Circadian entrainment_Homo sapiens_hsa04713 | 0.72668394 |
| 54 | Taste transduction_Homo sapiens_hsa04742 | 0.72374577 |
| 55 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.72123124 |
| 56 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.70884446 |
| 57 | Apoptosis_Homo sapiens_hsa04210 | 0.69172498 |
| 58 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.68974859 |
| 59 | Gap junction_Homo sapiens_hsa04540 | 0.68299180 |
| 60 | Salivary secretion_Homo sapiens_hsa04970 | 0.67258414 |
| 61 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.66596920 |
| 62 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.65570366 |
| 63 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.65328478 |
| 64 | Galactose metabolism_Homo sapiens_hsa00052 | 0.63735328 |
| 65 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.61956383 |
| 66 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.61206999 |
| 67 | Melanoma_Homo sapiens_hsa05218 | 0.59587640 |
| 68 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.59174762 |
| 69 | Renin secretion_Homo sapiens_hsa04924 | 0.58583371 |
| 70 | Metabolic pathways_Homo sapiens_hsa01100 | 0.57768365 |
| 71 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.57500165 |
| 72 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.56212312 |
| 73 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.55946855 |
| 74 | Base excision repair_Homo sapiens_hsa03410 | 0.52931801 |
| 75 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.52713233 |
| 76 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.52639949 |
| 77 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.49537688 |
| 78 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.48536861 |
| 79 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.45369113 |
| 80 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.44080494 |
| 81 | Alcoholism_Homo sapiens_hsa05034 | 0.43018037 |
| 82 | GABAergic synapse_Homo sapiens_hsa04727 | 0.41792344 |
| 83 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.41471991 |
| 84 | Parkinsons disease_Homo sapiens_hsa05012 | 0.41151725 |
| 85 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.38293533 |
| 86 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.36664075 |
| 87 | Mismatch repair_Homo sapiens_hsa03430 | 0.36524718 |
| 88 | Tight junction_Homo sapiens_hsa04530 | 0.35901966 |
| 89 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.33154276 |
| 90 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.32815945 |
| 91 | Other glycan degradation_Homo sapiens_hsa00511 | 0.31957959 |
| 92 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.31398619 |
| 93 | Phagosome_Homo sapiens_hsa04145 | 0.29018571 |
| 94 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.28096106 |
| 95 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.27873519 |
| 96 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.26697938 |
| 97 | Alzheimers disease_Homo sapiens_hsa05010 | 0.26639250 |
| 98 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.25341203 |
| 99 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.24805505 |
| 100 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.24400168 |

