Rank | Gene Set | Z-score |
---|---|---|
1 | positive regulation of megakaryocyte differentiation (GO:0045654) | 9.72713747 |
2 | cellular response to zinc ion (GO:0071294) | 8.79235910 |
3 | thrombin receptor signaling pathway (GO:0070493) | 8.46710810 |
4 | positive regulation of hematopoietic progenitor cell differentiation (GO:1901534) | 8.22434865 |
5 | * digestion (GO:0007586) | 7.91345434 |
6 | tyrosine phosphorylation of STAT protein (GO:0007260) | 7.77911542 |
7 | transcytosis (GO:0045056) | 7.68862300 |
8 | production of molecular mediator involved in inflammatory response (GO:0002532) | 7.16118923 |
9 | low-density lipoprotein particle clearance (GO:0034383) | 7.14545010 |
10 | peptidyl-proline hydroxylation (GO:0019511) | 6.85251564 |
11 | regulation of sequestering of triglyceride (GO:0010889) | 6.68765622 |
12 | cellular response to cadmium ion (GO:0071276) | 6.25712121 |
13 | negative regulation of digestive system process (GO:0060457) | 6.14102392 |
14 | intestinal absorption (GO:0050892) | 5.97575410 |
15 | COPI coating of Golgi vesicle (GO:0048205) | 5.94070446 |
16 | Golgi transport vesicle coating (GO:0048200) | 5.94070446 |
17 | valine metabolic process (GO:0006573) | 5.46976684 |
18 | protein hydroxylation (GO:0018126) | 5.46807092 |
19 | leukotriene biosynthetic process (GO:0019370) | 5.28623148 |
20 | exocrine pancreas development (GO:0031017) | 5.20045010 |
21 | citrulline biosynthetic process (GO:0019240) | 5.03875285 |
22 | regulation of phospholipase A2 activity (GO:0032429) | 4.89941162 |
23 | lipid storage (GO:0019915) | 4.76913899 |
24 | sterol catabolic process (GO:0016127) | 4.73324263 |
25 | cholesterol catabolic process (GO:0006707) | 4.73324263 |
26 | triglyceride catabolic process (GO:0019433) | 4.61646224 |
27 | angiotensin maturation (GO:0002003) | 4.60946830 |
28 | positive regulation of Rho protein signal transduction (GO:0035025) | 4.59835962 |
29 | positive regulation of lipid storage (GO:0010884) | 4.50429468 |
30 | platelet dense granule organization (GO:0060155) | 4.42320588 |
31 | diacylglycerol metabolic process (GO:0046339) | 4.39651155 |
32 | neutral lipid catabolic process (GO:0046461) | 4.32426117 |
33 | acylglycerol catabolic process (GO:0046464) | 4.32426117 |
34 | branched-chain amino acid catabolic process (GO:0009083) | 4.24726323 |
35 | branched-chain amino acid metabolic process (GO:0009081) | 4.12062423 |
36 | membrane lipid catabolic process (GO:0046466) | 4.02550123 |
37 | cobalamin metabolic process (GO:0009235) | 4.02225617 |
38 | regulation of megakaryocyte differentiation (GO:0045652) | 4.00057414 |
39 | negative regulation of bone resorption (GO:0045779) | 3.95641814 |
40 | membrane repolarization during cardiac muscle cell action potential (GO:0086013) | 3.91223042 |
41 | activation of signaling protein activity involved in unfolded protein response (GO:0006987) | 3.88891266 |
42 | glycolipid catabolic process (GO:0019377) | 3.87162850 |
43 | negative regulation of lipid storage (GO:0010888) | 3.84002620 |
44 | maintenance of protein localization in organelle (GO:0072595) | 3.79405274 |
45 | positive regulation of nuclease activity (GO:0032075) | 3.72988433 |
46 | regulation of lipid storage (GO:0010883) | 3.72505034 |
47 | regulation of glomerular filtration (GO:0003093) | 3.72259638 |
48 | actin nucleation (GO:0045010) | 3.66320630 |
49 | insulin-like growth factor receptor signaling pathway (GO:0048009) | 3.61758356 |
50 | 4-hydroxyproline metabolic process (GO:0019471) | 3.58956280 |
51 | L-alpha-amino acid transmembrane transport (GO:1902475) | 3.58931070 |
52 | germ cell migration (GO:0008354) | 3.57569960 |
53 | coenzyme catabolic process (GO:0009109) | 3.56685079 |
54 | response to laminar fluid shear stress (GO:0034616) | 3.53155593 |
55 | COPII vesicle coating (GO:0048208) | 3.50530207 |
56 | positive regulation of interleukin-8 secretion (GO:2000484) | 3.49607716 |
57 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 3.49117473 |
58 | positive regulation of histone deacetylation (GO:0031065) | 3.48938249 |
59 | potassium ion export (GO:0071435) | 3.47029952 |
60 | negative regulation of platelet activation (GO:0010544) | 3.46475783 |
61 | positive regulation of pseudopodium assembly (GO:0031274) | 3.45534978 |
62 | membrane repolarization during action potential (GO:0086011) | 3.44356074 |
63 | hydrogen peroxide metabolic process (GO:0042743) | 3.43851371 |
64 | cysteine metabolic process (GO:0006534) | 3.43055190 |
65 | regulation of triglyceride catabolic process (GO:0010896) | 3.42534281 |
66 | mannose metabolic process (GO:0006013) | 3.41862819 |
67 | cardiovascular system development (GO:0072358) | 3.40393918 |
68 | regulation of heterotypic cell-cell adhesion (GO:0034114) | 3.39826015 |
69 | actin filament capping (GO:0051693) | 3.38545571 |
70 | regulation of nuclease activity (GO:0032069) | 3.34418838 |
71 | positive regulation of glomerulus development (GO:0090193) | 3.33201308 |
72 | plasma lipoprotein particle clearance (GO:0034381) | 3.29012267 |
73 | ceramide catabolic process (GO:0046514) | 3.28067087 |
74 | branching involved in labyrinthine layer morphogenesis (GO:0060670) | 3.27276101 |
75 | fatty acid homeostasis (GO:0055089) | 3.25003127 |
76 | megakaryocyte development (GO:0035855) | 3.23784640 |
77 | positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:00360 | 3.22398987 |
78 | negative regulation of protein autophosphorylation (GO:0031953) | 3.20665516 |
79 | N-glycan processing (GO:0006491) | 3.19504948 |
80 | regulation of uterine smooth muscle contraction (GO:0070472) | 3.18968948 |
81 | peptide catabolic process (GO:0043171) | 3.18954691 |
82 | cellular modified amino acid catabolic process (GO:0042219) | 3.18653904 |
83 | regulation of digestive system process (GO:0044058) | 3.18580861 |
84 | homeostasis of number of cells within a tissue (GO:0048873) | 3.18074205 |
85 | positive regulation of heat generation (GO:0031652) | 3.16137824 |
86 | endoplasmic reticulum unfolded protein response (GO:0030968) | 3.15621035 |
87 | growth hormone receptor signaling pathway (GO:0060396) | 3.15374270 |
88 | adhesion of symbiont to host (GO:0044406) | 3.13745575 |
89 | retrograde vesicle-mediated transport, Golgi to ER (GO:0006890) | 3.13348858 |
90 | virion attachment to host cell (GO:0019062) | 3.13262129 |
91 | adhesion of symbiont to host cell (GO:0044650) | 3.13262129 |
92 | positive regulation of triglyceride metabolic process (GO:0090208) | 3.12154098 |
93 | negative regulation of lipid catabolic process (GO:0050995) | 3.12012407 |
94 | ovulation from ovarian follicle (GO:0001542) | 3.11821073 |
95 | notochord development (GO:0030903) | 3.11625146 |
96 | leukotriene metabolic process (GO:0006691) | 3.09517814 |
97 | positive regulation of p38MAPK cascade (GO:1900745) | 3.09506407 |
98 | glycerolipid catabolic process (GO:0046503) | 3.09171970 |
99 | positive regulation of tyrosine phosphorylation of Stat1 protein (GO:0042511) | 3.09124347 |
100 | negative regulation of bone remodeling (GO:0046851) | 3.08672643 |
101 | positive regulation of digestive system process (GO:0060456) | 3.06601119 |
102 | embryonic foregut morphogenesis (GO:0048617) | 3.06456149 |
103 | regulation of cholesterol storage (GO:0010885) | 3.06323200 |
104 | response to endoplasmic reticulum stress (GO:0034976) | 3.06222643 |
105 | triglyceride metabolic process (GO:0006641) | 3.05206984 |
106 | vesicle coating (GO:0006901) | 3.03742657 |
107 | atrial cardiac muscle cell action potential (GO:0086014) | 3.02599874 |
108 | long term synaptic depression (GO:0060292) | 3.02489505 |
109 | acute-phase response (GO:0006953) | 3.00193572 |
110 | citrulline metabolic process (GO:0000052) | 3.00151502 |
111 | negative regulation of granulocyte differentiation (GO:0030853) | 2.99775667 |
112 | cellular response to unfolded protein (GO:0034620) | 2.99537547 |
113 | proline biosynthetic process (GO:0006561) | 2.98903066 |
114 | negative regulation of macrophage differentiation (GO:0045650) | 2.98633964 |
115 | protein heterotrimerization (GO:0070208) | 2.98220417 |
116 | fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540) | 2.97827902 |
117 | lipid particle organization (GO:0034389) | 2.97342266 |
118 | regulation of fever generation (GO:0031620) | 2.96136793 |
119 | response to zinc ion (GO:0010043) | 2.95452909 |
120 | biotin metabolic process (GO:0006768) | 2.93694051 |
121 | alpha-linolenic acid metabolic process (GO:0036109) | 2.93544089 |
122 | sulfation (GO:0051923) | 2.93290480 |
123 | glutathione biosynthetic process (GO:0006750) | 2.92805799 |
124 | acylglycerol metabolic process (GO:0006639) | 2.92324933 |
125 | DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 cla | 2.91994512 |
126 | endocardial cushion development (GO:0003197) | 2.91558135 |
127 | regulation of mononuclear cell migration (GO:0071675) | 2.91458045 |
128 | ER-nucleus signaling pathway (GO:0006984) | 2.90890205 |
129 | cellular response to epinephrine stimulus (GO:0071872) | 2.90603463 |
130 | renal system process involved in regulation of blood volume (GO:0001977) | 2.89903308 |
131 | regulation of metalloenzyme activity (GO:0048552) | 2.89610604 |
132 | complement activation, alternative pathway (GO:0006957) | 2.88416999 |
133 | neutral lipid metabolic process (GO:0006638) | 2.87034893 |
134 | positive regulation of cholesterol efflux (GO:0010875) | 2.85630629 |
135 | maintenance of gastrointestinal epithelium (GO:0030277) | 2.85469576 |
136 | regulation of lymphocyte chemotaxis (GO:1901623) | 2.85029320 |
137 | negative regulation of hydrogen peroxide-induced cell death (GO:1903206) | 2.84650671 |
138 | skeletal muscle organ development (GO:0060538) | 2.84642331 |
139 | endothelium development (GO:0003158) | 2.82741313 |
140 | regulation of pseudopodium assembly (GO:0031272) | 2.82552293 |
141 | negative regulation of leukocyte chemotaxis (GO:0002689) | 2.82042003 |
142 | negative regulation of actin filament depolymerization (GO:0030835) | 2.81092930 |
143 | negative regulation of smooth muscle cell proliferation (GO:0048662) | 2.80763688 |
144 | response to follicle-stimulating hormone (GO:0032354) | 2.78744138 |
145 | water-soluble vitamin metabolic process (GO:0006767) | 2.78079621 |
146 | negative regulation of cell size (GO:0045792) | 2.77747255 |
147 | cellular response to topologically incorrect protein (GO:0035967) | 2.77644216 |
148 | negative regulation of endothelial cell apoptotic process (GO:2000352) | 2.76520848 |
149 | activation of protein kinase B activity (GO:0032148) | 2.76367350 |
150 | positive regulation of calcium ion transport into cytosol (GO:0010524) | 2.75735391 |
151 | ventricular cardiac muscle cell action potential (GO:0086005) | 2.74625396 |
152 | UDP-N-acetylglucosamine metabolic process (GO:0006047) | 2.74119136 |
153 | eosinophil chemotaxis (GO:0048245) | 2.74072528 |
154 | negative regulation of smooth muscle cell migration (GO:0014912) | 2.73772217 |
155 | negative regulation of phagocytosis (GO:0050765) | 2.73671443 |
156 | regulation of chemokine-mediated signaling pathway (GO:0070099) | 2.73435588 |
157 | myelin maintenance (GO:0043217) | 2.73357787 |
158 | oxaloacetate metabolic process (GO:0006107) | 2.72970028 |
159 | regulation of translation in response to stress (GO:0043555) | 2.72794923 |
160 | retina vasculature morphogenesis in camera-type eye (GO:0061299) | 2.72750098 |
161 | cellular response to fluid shear stress (GO:0071498) | 2.70340298 |
162 | regulation of hormone metabolic process (GO:0032350) | 2.67974756 |
163 | CDP-diacylglycerol biosynthetic process (GO:0016024) | 2.67678791 |
164 | regulation of membrane protein ectodomain proteolysis (GO:0051043) | 2.67395028 |
165 | nonribosomal peptide biosynthetic process (GO:0019184) | 2.66303928 |
166 | negative regulation of macrophage derived foam cell differentiation (GO:0010745) | 2.65505631 |
167 | triglyceride biosynthetic process (GO:0019432) | 2.65477896 |
168 | xenobiotic catabolic process (GO:0042178) | 2.64882305 |
169 | brown fat cell differentiation (GO:0050873) | 2.63713683 |
170 | positive regulation of smooth muscle cell migration (GO:0014911) | 2.60942068 |
171 | neutral lipid biosynthetic process (GO:0046460) | 2.60229396 |
172 | acylglycerol biosynthetic process (GO:0046463) | 2.60229396 |
173 | negative regulation of response to reactive oxygen species (GO:1901032) | 2.59415231 |
174 | regulation of hydrogen peroxide-induced cell death (GO:1903205) | 2.59248695 |
175 | positive regulation of metanephros development (GO:0072216) | 2.58595965 |
176 | regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307) | 2.58463423 |
177 | polarized epithelial cell differentiation (GO:0030859) | 2.57957119 |
178 | negative regulation of tumor necrosis factor production (GO:0032720) | 2.55526831 |
179 | regulation of triglyceride metabolic process (GO:0090207) | 2.54417000 |
180 | fatty-acyl-CoA biosynthetic process (GO:0046949) | 2.52228741 |
181 | serine transport (GO:0032329) | 2.51346466 |
182 | hypotonic response (GO:0006971) | 2.50284070 |
183 | tetrapyrrole metabolic process (GO:0033013) | 2.50256581 |
184 | retinol metabolic process (GO:0042572) | 2.48849374 |
185 | positive regulation of membrane protein ectodomain proteolysis (GO:0051044) | 2.48116945 |
186 | regulation of heat generation (GO:0031650) | 2.46572235 |
187 | negative regulation of tumor necrosis factor superfamily cytokine production (GO:1903556) | 2.46238734 |
188 | monocyte chemotaxis (GO:0002548) | 2.46152533 |
189 | CDP-diacylglycerol metabolic process (GO:0046341) | 2.46101746 |
190 | L-serine transport (GO:0015825) | 2.45799791 |
191 | intestinal cholesterol absorption (GO:0030299) | 13.4403465 |
192 | protein retention in ER lumen (GO:0006621) | 11.0932705 |
193 | maintenance of protein localization in endoplasmic reticulum (GO:0035437) | 10.0991122 |
Rank | Gene Set | Z-score |
---|---|---|
1 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 5.18586405 |
2 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 4.69884899 |
3 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 4.60894307 |
4 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 4.11597586 |
5 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 3.45859615 |
6 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 2.84738424 |
7 | SCL_19346495_ChIP-Seq_HPC-7_Human | 2.69857873 |
8 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 2.68593066 |
9 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 2.64450891 |
10 | SOX2_27498859_Chip-Seq_STOMACH_Mouse | 2.55353366 |
11 | SALL4_18804426_ChIP-ChIP_XEN_Mouse | 2.30999316 |
12 | GATA4_25053715_ChIP-Seq_YYC3_Human | 2.28574848 |
13 | MYC_22102868_ChIP-Seq_BL_Human | 2.21055777 |
14 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 2.19359783 |
15 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 2.14659927 |
16 | GATA6_25053715_ChIP-Seq_YYC3_Human | 2.12135528 |
17 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 2.12052761 |
18 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 2.07755854 |
19 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 2.05658136 |
20 | SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 2.02892302 |
21 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 2.00548441 |
22 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 2.00548441 |
23 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 2.00548441 |
24 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.78222639 |
25 | * POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.76681793 |
26 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.76564960 |
27 | * TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.76090627 |
28 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.75017766 |
29 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.72887897 |
30 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 1.71558328 |
31 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.65841083 |
32 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 1.63602273 |
33 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 1.62820386 |
34 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 1.61284894 |
35 | SALL4_18804426_ChIP-ChIP_MESCs_Mouse | 1.60597887 |
36 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.59806654 |
37 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.57597533 |
38 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 1.56256603 |
39 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.55227124 |
40 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.54331539 |
41 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.53185976 |
42 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.49989509 |
43 | * LXR_22158963_ChIP-Seq_LIVER_Mouse | 1.49332376 |
44 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.49174634 |
45 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.47827341 |
46 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.46519513 |
47 | ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.44747663 |
48 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.44373396 |
49 | ZIC3_20872845_ChIP-ChIP_MESCs_Mouse | 1.42773324 |
50 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.42716649 |
51 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.42456263 |
52 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 1.39671423 |
53 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 1.39209380 |
54 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.37935023 |
55 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.35686185 |
56 | E2F7_22180533_ChIP-Seq_HELA_Human | 1.35578907 |
57 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.34091940 |
58 | PKCTHETA_26484144_Chip-Seq_BREAST_Human | 1.32224109 |
59 | GATA1_19941826_ChIP-Seq_K562_Human | 1.29767834 |
60 | FOXA2_19822575_ChIP-Seq_HepG2_Human | 1.26672330 |
61 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 1.26328592 |
62 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.25848645 |
63 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.24993248 |
64 | ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.23808824 |
65 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.23579677 |
66 | TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.22563747 |
67 | TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 1.21727933 |
68 | * NANOG_21062744_ChIP-ChIP_HESCs_Human | 1.21610247 |
69 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 1.21463548 |
70 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.21255861 |
71 | SOX2_18358816_ChIP-ChIP_MESCs_Mouse | 1.20108220 |
72 | UTX_26944678_Chip-Seq_JUKART_Human | 1.20086194 |
73 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.20060046 |
74 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.19689380 |
75 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.19587048 |
76 | TCF3_18692474_ChIP-Seq_MEFs_Mouse | 1.19406480 |
77 | RUNX1_27514584_Chip-Seq_MCF-7_Human | 1.18876075 |
78 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 1.18014415 |
79 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.17865527 |
80 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.17568606 |
81 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.17451300 |
82 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.16851471 |
83 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.16791368 |
84 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.16178565 |
85 | * CJUN_26792858_Chip-Seq_BT549_Human | 1.16019791 |
86 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.15909163 |
87 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.15738060 |
88 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.14812473 |
89 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.14795729 |
90 | GATA3_24758297_ChIP-Seq_MCF-7_Human | 1.13948001 |
91 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.13393360 |
92 | CREB1_26743006_Chip-Seq_LNCaP_Human | 1.13345095 |
93 | CHD1_26751641_Chip-Seq_LNCaP_Human | 1.13071387 |
94 | PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 1.12879712 |
95 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.12515691 |
96 | EGR1_19032775_ChIP-ChIP_M12_Human | 1.11805285 |
97 | STAT1_20625510_ChIP-Seq_HELA_Human | 1.11348972 |
98 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 1.11179006 |
99 | FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.10466791 |
100 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.09240458 |
101 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.09103933 |
102 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 1.07690644 |
103 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 1.07312184 |
104 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.07309159 |
105 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.06913272 |
106 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.05418634 |
107 | ATF3_27146783_Chip-Seq_COLON_Human | 1.05373543 |
108 | SOX2_20726797_ChIP-Seq_SW620_Human | 1.05316675 |
109 | MYB_26560356_Chip-Seq_TH2_Human | 1.05088640 |
110 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 1.05024510 |
111 | SA1_27219007_Chip-Seq_Bcells_Human | 1.04355923 |
112 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.03352545 |
113 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 1.03051904 |
114 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.02828371 |
115 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.02454815 |
116 | JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.02410569 |
117 | CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 1.02321003 |
118 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.01780122 |
119 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.01777324 |
120 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 1.01581147 |
121 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.01233107 |
122 | FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human | 1.00948481 |
123 | CDX2_20551321_ChIP-Seq_CACO-2_Human | 1.00541695 |
124 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 0.99838703 |
125 | NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 0.99827340 |
126 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 0.99639818 |
127 | JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.99581084 |
128 | MAF_26560356_Chip-Seq_TH1_Human | 0.99200335 |
129 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 0.98870221 |
130 | * GATA1_22383799_ChIP-Seq_G1ME_Mouse | 0.98806723 |
131 | TFAP2A_17053090_ChIP-ChIP_MCF-7_Human | 0.97942218 |
132 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 0.96795649 |
133 | RUNX_20019798_ChIP-Seq_JUKART_Human | 0.95653863 |
134 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.95463716 |
135 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 0.95055727 |
136 | TBX20_22328084_ChIP-Seq_HEART_Mouse | 0.95016546 |
137 | TBX20_22080862_ChIP-Seq_HEART_Mouse | 0.95016546 |
138 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 0.94767721 |
139 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 0.94767721 |
140 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 0.94764819 |
141 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 0.92673801 |
142 | * NANOG_18347094_ChIP-ChIP_MESCs_Mouse | 0.92335335 |
143 | SPI1_23127762_ChIP-Seq_K562_Human | 0.92331333 |
144 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 0.91987723 |
145 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 0.91222068 |
146 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.91021558 |
147 | * RAD21_21589869_ChIP-Seq_MESCs_Mouse | 0.90916906 |
148 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.89576423 |
149 | * SMC3_22415368_ChIP-Seq_MEFs_Mouse | 0.88069734 |
150 | CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.87795966 |
151 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 0.87281431 |
152 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 0.86733335 |
153 | ERA_21632823_ChIP-Seq_H3396_Human | 0.86620224 |
154 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 0.86454621 |
155 | EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 0.86267251 |
156 | SMC1_22415368_ChIP-Seq_MEFs_Mouse | 0.85683243 |
157 | KDM2B_26808549_Chip-Seq_K562_Human | 0.84193099 |
158 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 0.83275683 |
159 | * LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 0.82552215 |
160 | NFIB_24661679_ChIP-Seq_LUNG_Mouse | 0.81959496 |
161 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 0.81914415 |
162 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 0.81245556 |
163 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.80775737 |
164 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.80635546 |
165 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 0.80011953 |
166 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.79471393 |
167 | UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 0.79456367 |
168 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 0.79258270 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0005083_abnormal_biliary_tract | 9.43876625 |
2 | MP0001666_abnormal_nutrient_absorption | 7.60090776 |
3 | MP0005365_abnormal_bile_salt | 5.27918124 |
4 | MP0008004_abnormal_stomach_pH | 4.35176083 |
5 | MP0003868_abnormal_feces_composition | 4.32946538 |
6 | MP0005085_abnormal_gallbladder_physiolo | 4.18388182 |
7 | MP0005084_abnormal_gallbladder_morpholo | 4.10055639 |
8 | MP0005670_abnormal_white_adipose | 3.67228035 |
9 | MP0002877_abnormal_melanocyte_morpholog | 3.23053268 |
10 | MP0003724_increased_susceptibility_to | 3.02637890 |
11 | MP0009840_abnormal_foam_cell | 2.88346985 |
12 | MP0003303_peritoneal_inflammation | 2.81626286 |
13 | MP0005666_abnormal_adipose_tissue | 2.74140272 |
14 | MP0005220_abnormal_exocrine_pancreas | 2.57210310 |
15 | MP0004858_abnormal_nervous_system | 2.50638369 |
16 | MP0002971_abnormal_brown_adipose | 2.47106425 |
17 | MP0005167_abnormal_blood-brain_barrier | 2.39696587 |
18 | MP0003806_abnormal_nucleotide_metabolis | 2.27003608 |
19 | MP0003011_delayed_dark_adaptation | 2.26106670 |
20 | MP0005623_abnormal_meninges_morphology | 2.24617843 |
21 | MP0002139_abnormal_hepatobiliary_system | 2.22608613 |
22 | MP0002876_abnormal_thyroid_physiology | 2.16751891 |
23 | MP0010234_abnormal_vibrissa_follicle | 2.04863636 |
24 | MP0001661_extended_life_span | 1.93206507 |
25 | MP0005451_abnormal_body_composition | 1.91216222 |
26 | MP0001664_abnormal_digestion | 1.88704970 |
27 | MP0002295_abnormal_pulmonary_circulatio | 1.87000666 |
28 | MP0009384_cardiac_valve_regurgitation | 1.86192005 |
29 | MP0005334_abnormal_fat_pad | 1.86029359 |
30 | MP0004264_abnormal_extraembryonic_tissu | 1.82544784 |
31 | MP0003705_abnormal_hypodermis_morpholog | 1.78166410 |
32 | MP0005375_adipose_tissue_phenotype | 1.78015604 |
33 | MP0002837_dystrophic_cardiac_calcinosis | 1.72366217 |
34 | MP0003959_abnormal_lean_body | 1.67683946 |
35 | MP0003436_decreased_susceptibility_to | 1.65802064 |
36 | MP0006138_congestive_heart_failure | 1.64780535 |
37 | MP0004130_abnormal_muscle_cell | 1.63938082 |
38 | MP0006054_spinal_hemorrhage | 1.63784481 |
39 | MP0003329_amyloid_beta_deposits | 1.59539065 |
40 | MP0005535_abnormal_body_temperature | 1.54569703 |
41 | MP0005647_abnormal_sex_gland | 1.48444252 |
42 | MP0003279_aneurysm | 1.47968410 |
43 | MP0002970_abnormal_white_adipose | 1.43966643 |
44 | MP0009115_abnormal_fat_cell | 1.43412368 |
45 | MP0003879_abnormal_hair_cell | 1.42519523 |
46 | MP0003075_altered_response_to | 1.41442054 |
47 | MP0001533_abnormal_skeleton_physiology | 1.39801043 |
48 | MP0003828_pulmonary_edema | 1.38300484 |
49 | MP0004883_abnormal_blood_vessel | 1.35442760 |
50 | MP0006082_CNS_inflammation | 1.33511856 |
51 | MP0005595_abnormal_vascular_smooth | 1.33438850 |
52 | MP0010352_gastrointestinal_tract_polyps | 1.27289694 |
53 | MP0009278_abnormal_bone_marrow | 1.25462289 |
54 | MP0010329_abnormal_lipoprotein_level | 1.22559432 |
55 | MP0002148_abnormal_hypersensitivity_rea | 1.22511836 |
56 | MP0002419_abnormal_innate_immunity | 1.22020755 |
57 | MP0000465_gastrointestinal_hemorrhage | 1.21449182 |
58 | MP0000749_muscle_degeneration | 1.21029926 |
59 | MP0003186_abnormal_redox_activity | 1.20352236 |
60 | MP0005410_abnormal_fertilization | 1.19620797 |
61 | MP0009785_altered_susceptibility_to | 1.17175131 |
62 | MP0002998_abnormal_bone_remodeling | 1.15293325 |
63 | MP0003690_abnormal_glial_cell | 1.13732700 |
64 | MP0004808_abnormal_hematopoietic_stem | 1.13624738 |
65 | MP0002254_reproductive_system_inflammat | 1.13412932 |
66 | MP0003300_gastrointestinal_ulcer | 1.13405510 |
67 | MP0003656_abnormal_erythrocyte_physiolo | 1.13071492 |
68 | MP0001501_abnormal_sleep_pattern | 1.12279794 |
69 | MP0010368_abnormal_lymphatic_system | 1.11702968 |
70 | MP0005310_abnormal_salivary_gland | 1.11404081 |
71 | MP0000490_abnormal_crypts_of | 1.10837896 |
72 | MP0000767_abnormal_smooth_muscle | 1.10441675 |
73 | MP0001915_intracranial_hemorrhage | 1.08897905 |
74 | MP0000470_abnormal_stomach_morphology | 1.08745876 |
75 | MP0002693_abnormal_pancreas_physiology | 1.08658808 |
76 | MP0004084_abnormal_cardiac_muscle | 1.03654237 |
77 | MP0003638_abnormal_response/metabolism_ | 1.03406501 |
78 | MP0003566_abnormal_cell_adhesion | 1.02513520 |
79 | MP0004185_abnormal_adipocyte_glucose | 1.02052851 |
80 | MP0008770_decreased_survivor_rate | 1.01476906 |
81 | MP0002118_abnormal_lipid_homeostasis | 1.00891993 |
82 | MP0005025_abnormal_response_to | 1.00515956 |
83 | MP0005408_hypopigmentation | 0.98869210 |
84 | MP0010678_abnormal_skin_adnexa | 0.98614551 |
85 | MP0003453_abnormal_keratinocyte_physiol | 0.98543795 |
86 | MP0004233_abnormal_muscle_weight | 0.97307290 |
87 | MP0004272_abnormal_basement_membrane | 0.96228367 |
88 | MP0008469_abnormal_protein_level | 0.95815693 |
89 | MP0001545_abnormal_hematopoietic_system | 0.93143569 |
90 | MP0005397_hematopoietic_system_phenotyp | 0.93143569 |
91 | MP0000343_altered_response_to | 0.91852213 |
92 | MP0005000_abnormal_immune_tolerance | 0.90600933 |
93 | MP0005464_abnormal_platelet_physiology | 0.90261866 |
94 | MP0000604_amyloidosis | 0.88328601 |
95 | MP0000249_abnormal_blood_vessel | 0.87881489 |
96 | MP0002078_abnormal_glucose_homeostasis | 0.87715034 |
97 | MP0008961_abnormal_basal_metabolism | 0.87194739 |
98 | MP0003252_abnormal_bile_duct | 0.85256425 |
99 | MP0002132_abnormal_respiratory_system | 0.84758621 |
100 | MP0005452_abnormal_adipose_tissue | 0.84397719 |
101 | MP0009333_abnormal_splenocyte_physiolog | 0.84047039 |
102 | MP0005058_abnormal_lysosome_morphology | 0.83740827 |
103 | MP0005584_abnormal_enzyme/coenzyme_acti | 0.83596758 |
104 | MP0004947_skin_inflammation | 0.81758856 |
105 | MP0002405_respiratory_system_inflammati | 0.80218803 |
106 | MP0000598_abnormal_liver_morphology | 0.79775655 |
107 | MP0001485_abnormal_pinna_reflex | 0.78661775 |
108 | MP0005332_abnormal_amino_acid | 0.77393310 |
109 | MP0001853_heart_inflammation | 0.76410829 |
110 | MP0010155_abnormal_intestine_physiology | 0.76110212 |
111 | MP0004147_increased_porphyrin_level | 0.75496694 |
112 | MP0001756_abnormal_urination | 0.75352440 |
113 | MP0001542_abnormal_bone_strength | 0.74537018 |
114 | MP0009765_abnormal_xenobiotic_induced | 0.72868421 |
115 | MP0005448_abnormal_energy_balance | 0.72771837 |
116 | MP0005275_abnormal_skin_tensile | 0.71989062 |
117 | MP0005390_skeleton_phenotype | 0.71677685 |
118 | MP0002638_abnormal_pupillary_reflex | 0.71548921 |
119 | MP0004019_abnormal_vitamin_homeostasis | 0.70283660 |
120 | MP0000383_abnormal_hair_follicle | 0.70011363 |
121 | MP0004036_abnormal_muscle_relaxation | 0.69436418 |
122 | MP0003941_abnormal_skin_development | 0.68973971 |
123 | MP0000230_abnormal_systemic_arterial | 0.66666548 |
124 | MP0000751_myopathy | 0.66555491 |
125 | MP0003221_abnormal_cardiomyocyte_apopto | 0.66209804 |
126 | MP0006036_abnormal_mitochondrial_physio | 0.65357716 |
127 | MP0005164_abnormal_response_to | 0.61793499 |
128 | MP0001944_abnormal_pancreas_morphology | 0.60397708 |
129 | MP0004957_abnormal_blastocyst_morpholog | 0.59734286 |
130 | MP0001873_stomach_inflammation | 0.57809699 |
131 | MP0005165_increased_susceptibility_to | 0.57715001 |
132 | MP0000609_abnormal_liver_physiology | 0.56979899 |
133 | MP0004510_myositis | 0.56495916 |
134 | MP0004885_abnormal_endolymph | 0.54912163 |
135 | MP0003943_abnormal_hepatobiliary_system | 0.54014211 |
136 | MP0002086_abnormal_extraembryonic_tissu | 0.53842787 |
137 | MP0005387_immune_system_phenotype | 0.51445451 |
138 | MP0001790_abnormal_immune_system | 0.51445451 |
139 | MP0008438_abnormal_cutaneous_collagen | 0.50921613 |
140 | MP0003795_abnormal_bone_structure | 0.50892430 |
141 | MP0001845_abnormal_inflammatory_respons | 0.49339716 |
142 | MP0001663_abnormal_digestive_system | 0.49144013 |
143 | MP0001849_ear_inflammation | 0.45561171 |
144 | MP0005174_abnormal_tail_pigmentation | 0.45473236 |
145 | MP0005671_abnormal_response_to | 0.45273961 |
146 | MP0003866_abnormal_defecation | 0.45118894 |
147 | MP0008873_increased_physiological_sensi | 0.44411240 |
148 | MP0009763_increased_sensitivity_to | 0.43599683 |
149 | MP0010307_abnormal_tumor_latency | 0.43076220 |
150 | MP0003172_abnormal_lysosome_physiology | 0.42584207 |
151 | MP0002138_abnormal_hepatobiliary_system | 0.41920431 |
152 | MP0003448_altered_tumor_morphology | 0.41392056 |
153 | MP0003984_embryonic_growth_retardation | 0.40059372 |
154 | MP0004134_abnormal_chest_morphology | 0.39557073 |
155 | MP0001697_abnormal_embryo_size | 0.38728535 |
156 | MP0002269_muscular_atrophy | 0.38457428 |
157 | MP0009643_abnormal_urine_homeostasis | 0.37724260 |
158 | MP0003953_abnormal_hormone_level | 0.36802783 |
159 | MP0001672_abnormal_embryogenesis/_devel | 0.36700801 |
160 | MP0005380_embryogenesis_phenotype | 0.36700801 |
161 | MP0001851_eye_inflammation | 0.36597649 |
162 | MP0002928_abnormal_bile_duct | 0.36456763 |
163 | MP0005319_abnormal_enzyme/_coenzyme | 0.36368141 |
164 | MP0003119_abnormal_digestive_system | 0.35919159 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Abnormal number of erythroid precursors (HP:0012131) | 6.54008236 |
2 | Gout (HP:0001997) | 6.41626208 |
3 | Abnormality of cells of the erythroid lineage (HP:0012130) | 6.20556820 |
4 | Increased mean platelet volume (HP:0011877) | 5.49425363 |
5 | Petechiae (HP:0000967) | 5.39278659 |
6 | Abnormal platelet volume (HP:0011876) | 5.01875147 |
7 | Menorrhagia (HP:0000132) | 4.56878027 |
8 | Ventricular fibrillation (HP:0001663) | 4.50383537 |
9 | Right ventricular cardiomyopathy (HP:0011663) | 4.48150251 |
10 | Axonal loss (HP:0003447) | 4.47557321 |
11 | Systemic lupus erythematosus (HP:0002725) | 4.30701843 |
12 | Congenital sensorineural hearing impairment (HP:0008527) | 4.24383699 |
13 | Cortical dysplasia (HP:0002539) | 4.15802173 |
14 | Hypertriglyceridemia (HP:0002155) | 4.09140745 |
15 | Abnormality of oral frenula (HP:0000190) | 4.08547691 |
16 | Abnormal pancreas size (HP:0012094) | 4.03431125 |
17 | Purpura (HP:0000979) | 4.02617179 |
18 | Complement deficiency (HP:0004431) | 3.95888041 |
19 | Megaloblastic anemia (HP:0001889) | 3.82482421 |
20 | Abnormality of glycolipid metabolism (HP:0010969) | 3.77220799 |
21 | Abnormality of liposaccharide metabolism (HP:0010968) | 3.77220799 |
22 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 3.77220799 |
23 | Carpal bone hypoplasia (HP:0001498) | 3.69397431 |
24 | Difficulty running (HP:0009046) | 3.65616927 |
25 | Glomerulonephritis (HP:0000099) | 3.60498206 |
26 | Acanthosis nigricans (HP:0000956) | 3.59005363 |
27 | Gingival bleeding (HP:0000225) | 3.52222451 |
28 | Nuclear cataract (HP:0100018) | 3.51809153 |
29 | Increased serum pyruvate (HP:0003542) | 3.48367052 |
30 | Increased purine levels (HP:0004368) | 3.35249726 |
31 | Hyperuricemia (HP:0002149) | 3.35249726 |
32 | Steatorrhea (HP:0002570) | 3.33326181 |
33 | Abnormal tarsal ossification (HP:0008369) | 3.31186270 |
34 | Fat malabsorption (HP:0002630) | 3.29997993 |
35 | Abnormal platelet function (HP:0011869) | 3.25437593 |
36 | Impaired platelet aggregation (HP:0003540) | 3.25437593 |
37 | Aplasia of the musculature (HP:0100854) | 3.23424987 |
38 | Hypoproteinemia (HP:0003075) | 3.22835271 |
39 | Abnormality of complement system (HP:0005339) | 3.15569635 |
40 | Mutism (HP:0002300) | 3.12538267 |
41 | Muscle fiber splitting (HP:0003555) | 3.10523649 |
42 | Fetal akinesia sequence (HP:0001989) | 3.09493378 |
43 | Tubulointerstitial nephritis (HP:0001970) | 3.04386138 |
44 | Premature skin wrinkling (HP:0100678) | 3.03275564 |
45 | Loss of speech (HP:0002371) | 3.00955479 |
46 | Oligomenorrhea (HP:0000876) | 3.00512149 |
47 | Diaphragmatic weakness (HP:0009113) | 2.98875378 |
48 | Tubulointerstitial fibrosis (HP:0005576) | 2.97439040 |
49 | Abnormality of glycolysis (HP:0004366) | 2.93166989 |
50 | Hyperglycinemia (HP:0002154) | 2.89778337 |
51 | Abnormality of endocrine pancreas physiology (HP:0012093) | 2.87270322 |
52 | Abnormality of the pancreatic islet cells (HP:0006476) | 2.87270322 |
53 | Spontaneous hematomas (HP:0007420) | 2.87170014 |
54 | Resting tremor (HP:0002322) | 2.85810490 |
55 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 2.83143778 |
56 | Abnormality of vitamin B metabolism (HP:0004340) | 2.81457351 |
57 | Disinhibition (HP:0000734) | 2.80644223 |
58 | Vacuolated lymphocytes (HP:0001922) | 2.80101535 |
59 | Bone cyst (HP:0012062) | 2.77772824 |
60 | Dysostosis multiplex (HP:0000943) | 2.77729336 |
61 | Small epiphyses (HP:0010585) | 2.77164108 |
62 | Prolonged bleeding time (HP:0003010) | 2.72810623 |
63 | Ankyloglossia (HP:0010296) | 2.72412156 |
64 | Abnormality of the periventricular white matter (HP:0002518) | 2.71233377 |
65 | Polyphagia (HP:0002591) | 2.66749901 |
66 | Hypoplasia of the odontoid process (HP:0003311) | 2.66193297 |
67 | Goiter (HP:0000853) | 2.57833716 |
68 | Insulin-resistant diabetes mellitus (HP:0000831) | 2.55545404 |
69 | Exocrine pancreatic insufficiency (HP:0001738) | 2.52932894 |
70 | Abnormal foot bone ossification (HP:0010675) | 2.52387851 |
71 | Obstructive sleep apnea (HP:0002870) | 2.48578528 |
72 | Gonadal dysgenesis (HP:0000133) | 2.47104656 |
73 | Neoplasm of head and neck (HP:0012288) | 2.46286454 |
74 | Esophageal neoplasm (HP:0100751) | 2.46286454 |
75 | Abnormality of vitamin metabolism (HP:0100508) | 2.45301536 |
76 | Insulin resistance (HP:0000855) | 2.42153337 |
77 | Increased CSF protein (HP:0002922) | 2.40814493 |
78 | Aplasia/Hypoplasia involving the carpal bones (HP:0006502) | 2.40267717 |
79 | Cervical subluxation (HP:0003308) | 2.39296426 |
80 | Rough bone trabeculation (HP:0100670) | 2.35343239 |
81 | Abnormality of the renal cortex (HP:0011035) | 2.35197384 |
82 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.34812560 |
83 | Abnormality of alanine metabolism (HP:0010916) | 2.34812560 |
84 | Hyperalaninemia (HP:0003348) | 2.34812560 |
85 | Hypoplasia of the pons (HP:0012110) | 2.34475994 |
86 | Abnormality of polysaccharide metabolism (HP:0011012) | 2.34349130 |
87 | Abnormality of glycosaminoglycan metabolism (HP:0004371) | 2.34349130 |
88 | Abnormality of mucopolysaccharide metabolism (HP:0011020) | 2.34349130 |
89 | Large hands (HP:0001176) | 2.33329159 |
90 | Abnormality of purine metabolism (HP:0004352) | 2.32817777 |
91 | Hyperglycinuria (HP:0003108) | 2.32794907 |
92 | Stridor (HP:0010307) | 2.31332286 |
93 | Increased muscle lipid content (HP:0009058) | 2.29484658 |
94 | Increased variability in muscle fiber diameter (HP:0003557) | 2.29177829 |
95 | Retinal atrophy (HP:0001105) | 2.29175444 |
96 | Abnormal trabecular bone morphology (HP:0100671) | 2.28205677 |
97 | Abnormality of proline metabolism (HP:0010907) | 2.27152040 |
98 | Hydroxyprolinuria (HP:0003080) | 2.27152040 |
99 | Tubular atrophy (HP:0000092) | 2.25760582 |
100 | Abnormality of macrophages (HP:0004311) | 2.23661077 |
101 | Growth hormone excess (HP:0000845) | 2.22617322 |
102 | Intrahepatic cholestasis (HP:0001406) | 2.22266666 |
103 | Renal salt wasting (HP:0000127) | 2.20333217 |
104 | Recurrent gram-negative bacterial infections (HP:0005420) | 2.18756315 |
105 | Nephritis (HP:0000123) | 2.18516931 |
106 | Distal lower limb muscle weakness (HP:0009053) | 2.17695034 |
107 | Apathy (HP:0000741) | 2.17643076 |
108 | Malnutrition (HP:0004395) | 2.17440151 |
109 | Easy fatigability (HP:0003388) | 2.15342745 |
110 | Severe short stature (HP:0003510) | 2.13851720 |
111 | Abnormality of the intrinsic pathway (HP:0010989) | 2.13140804 |
112 | Abnormality of the pleura (HP:0002103) | 2.13012722 |
113 | Limb hypertonia (HP:0002509) | 2.11059464 |
114 | Patent foramen ovale (HP:0001655) | 2.10509697 |
115 | Gowers sign (HP:0003391) | 2.09460088 |
116 | Abnormality of the pons (HP:0007361) | 2.08525865 |
117 | Amyloidosis (HP:0011034) | 2.07935540 |
118 | Abnormality of the odontoid process (HP:0003310) | 2.07382858 |
119 | Recurrent abscess formation (HP:0002722) | 2.06812033 |
120 | Abnormality of serine family amino acid metabolism (HP:0010894) | 2.05350084 |
121 | Abnormality of glycine metabolism (HP:0010895) | 2.05350084 |
122 | Testicular neoplasm (HP:0010788) | 2.04747197 |
123 | Xanthomatosis (HP:0000991) | 2.04422503 |
124 | Diminished motivation (HP:0000745) | 2.03416470 |
125 | Hemorrhage of the eye (HP:0011885) | 2.02174338 |
126 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 2.01788677 |
127 | Barrel-shaped chest (HP:0001552) | 2.01456081 |
128 | Spinal muscular atrophy (HP:0007269) | 1.99714475 |
129 | Myocardial infarction (HP:0001658) | 1.99484993 |
130 | Ventricular arrhythmia (HP:0004308) | 1.98860553 |
131 | Neoplasm of the peripheral nervous system (HP:0100007) | 1.98836875 |
132 | Scapular winging (HP:0003691) | 1.97818695 |
133 | Bulbar palsy (HP:0001283) | 1.97718572 |
134 | Prolonged neonatal jaundice (HP:0006579) | 1.95550565 |
135 | Conjugated hyperbilirubinemia (HP:0002908) | 1.94333952 |
136 | Infantile muscular hypotonia (HP:0008947) | 1.94258356 |
137 | Sudden cardiac death (HP:0001645) | 1.94151304 |
138 | Tetraplegia (HP:0002445) | 1.93676940 |
139 | Abnormality of the common coagulation pathway (HP:0010990) | 1.93513595 |
140 | Syncope (HP:0001279) | 1.91336074 |
141 | Hyperlipoproteinemia (HP:0010980) | 1.91212976 |
142 | Nausea (HP:0002018) | 1.90099726 |
143 | Heterochromia iridis (HP:0001100) | 1.89700348 |
144 | Joint hemorrhage (HP:0005261) | 1.89317531 |
145 | Vertebral compression fractures (HP:0002953) | 1.88738191 |
146 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 1.88200437 |
147 | Osteolytic defects of the hand bones (HP:0009699) | 1.88200437 |
148 | Abnormality of aromatic amino acid family metabolism (HP:0004338) | 1.88073466 |
149 | Rhabdomyolysis (HP:0003201) | 1.88005961 |
150 | Increased cerebral lipofuscin (HP:0011813) | 1.86548133 |
151 | Glomerulosclerosis (HP:0000096) | 1.86337098 |
152 | Flat acetabular roof (HP:0003180) | 1.86230787 |
153 | Aplastic anemia (HP:0001915) | 1.85845050 |
154 | Enlarged penis (HP:0000040) | 1.85125834 |
155 | Limb-girdle muscle atrophy (HP:0003797) | 1.85118835 |
156 | Deep venous thrombosis (HP:0002625) | 1.84510751 |
157 | Macroorchidism (HP:0000053) | 1.84234554 |
158 | Upper limb amyotrophy (HP:0009129) | 1.84202584 |
159 | Distal upper limb amyotrophy (HP:0007149) | 1.84202584 |
160 | Urinary glycosaminoglycan excretion (HP:0003541) | 1.83997951 |
161 | Mucopolysacchariduria (HP:0008155) | 1.83997951 |
162 | Peripheral demyelination (HP:0011096) | 1.83836084 |
163 | Long foot (HP:0001833) | 1.83686676 |
164 | Ketoacidosis (HP:0001993) | 1.83095921 |
165 | Cerebral aneurysm (HP:0004944) | 1.82195410 |
166 | Ketosis (HP:0001946) | 1.81870642 |
167 | Abnormality of sulfur amino acid metabolism (HP:0004339) | 1.81813618 |
168 | Macrocytic anemia (HP:0001972) | 1.81346681 |
169 | Abnormality of the alveolar ridges (HP:0006477) | 1.77444712 |
170 | Cerebellar dysplasia (HP:0007033) | 1.77326633 |
171 | Epiphyseal dysplasia (HP:0002656) | 1.77017896 |
172 | Bilateral sensorineural hearing impairment (HP:0008619) | 1.74856005 |
173 | Fibroma (HP:0010614) | 1.74547548 |
174 | Prolonged QT interval (HP:0001657) | 1.74295544 |
175 | Autoamputation (HP:0001218) | 1.73796283 |
176 | Periodontitis (HP:0000704) | 1.71461442 |
177 | Shallow orbits (HP:0000586) | 1.71014606 |
178 | Pancreatitis (HP:0001733) | 1.70515798 |
179 | Hemiplegia (HP:0002301) | 1.70307963 |
180 | Flattened epiphyses (HP:0003071) | 1.68526982 |
181 | Germ cell neoplasia (HP:0100728) | 1.68171551 |
182 | Polygenic inheritance (HP:0010982) | 1.67272265 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EEF2K | 5.62075272 |
2 | BCKDK | 4.71180064 |
3 | EIF2AK3 | 4.00591520 |
4 | IRAK3 | 3.94424652 |
5 | FRK | 3.64832762 |
6 | TAOK3 | 3.61035727 |
7 | PINK1 | 3.44244666 |
8 | TRIB3 | 3.20599027 |
9 | MAPKAPK3 | 2.97464558 |
10 | MATK | 2.93693640 |
11 | CAMK1D | 2.69904253 |
12 | LATS1 | 2.41851206 |
13 | EPHA3 | 2.38028354 |
14 | TGFBR2 | 2.17115242 |
15 | ZAP70 | 2.11905312 |
16 | KIT | 2.09462290 |
17 | PKN2 | 2.08931823 |
18 | BLK | 1.96467916 |
19 | NME1 | 1.95637219 |
20 | SCYL2 | 1.92749554 |
21 | PRKAA2 | 1.90582424 |
22 | DDR2 | 1.88588919 |
23 | TAOK2 | 1.81516369 |
24 | RIPK1 | 1.80553510 |
25 | CLK1 | 1.72663758 |
26 | RPS6KB2 | 1.69935276 |
27 | CAMK1G | 1.68621135 |
28 | PRPF4B | 1.68448989 |
29 | LRRK2 | 1.67412529 |
30 | OBSCN | 1.66409678 |
31 | TIE1 | 1.63604389 |
32 | CDK12 | 1.61409089 |
33 | EPHB2 | 1.57766261 |
34 | TRPM7 | 1.55835925 |
35 | CAMKK2 | 1.55578976 |
36 | MOS | 1.51661274 |
37 | STK24 | 1.48732312 |
38 | TBK1 | 1.47183404 |
39 | MUSK | 1.46769083 |
40 | MAP4K1 | 1.43734325 |
41 | PIM2 | 1.42553933 |
42 | PDK2 | 1.37899848 |
43 | SIK1 | 1.37785604 |
44 | ERN1 | 1.33117212 |
45 | MAPK7 | 1.29223497 |
46 | CDK6 | 1.28808982 |
47 | FGR | 1.18832634 |
48 | ABL2 | 1.18453285 |
49 | PDGFRB | 1.18318272 |
50 | MAP3K13 | 1.17707969 |
51 | CDK4 | 1.13033558 |
52 | TYK2 | 1.12452395 |
53 | TESK2 | 1.11783204 |
54 | LATS2 | 1.11014399 |
55 | MYLK | 1.10984363 |
56 | MAP3K3 | 1.07468759 |
57 | MARK3 | 1.06939397 |
58 | IKBKB | 1.06586023 |
59 | MAPK15 | 1.05729745 |
60 | FGFR2 | 1.03754727 |
61 | KSR2 | 1.03365966 |
62 | MAP2K2 | 1.02594345 |
63 | MAPKAPK5 | 1.00188977 |
64 | WNK4 | 0.99324872 |
65 | MAP3K7 | 0.98868386 |
66 | MAP3K1 | 0.97228470 |
67 | JAK3 | 0.97106553 |
68 | ADRBK2 | 0.96922916 |
69 | STK10 | 0.95360841 |
70 | RET | 0.95229029 |
71 | MAP2K1 | 0.95048361 |
72 | AKT3 | 0.91716082 |
73 | CAMK1 | 0.90004139 |
74 | GSK3A | 0.88877893 |
75 | MAPK4 | 0.88705943 |
76 | JAK2 | 0.87579008 |
77 | PIK3CA | 0.85286072 |
78 | FES | 0.85272112 |
79 | ARAF | 0.81749931 |
80 | PTK6 | 0.80712284 |
81 | NLK | 0.78989993 |
82 | MTOR | 0.77383713 |
83 | GRK7 | 0.77247880 |
84 | MAP3K9 | 0.77178187 |
85 | PIM1 | 0.75267241 |
86 | MAP3K2 | 0.73751866 |
87 | ADRBK1 | 0.73292891 |
88 | TYRO3 | 0.72671764 |
89 | NTRK2 | 0.72554854 |
90 | PRKAA1 | 0.71755719 |
91 | PRKG2 | 0.68049039 |
92 | MAPK11 | 0.65063404 |
93 | IKBKE | 0.64871478 |
94 | PRKD2 | 0.63719295 |
95 | STK3 | 0.63280939 |
96 | FGFR3 | 0.61662866 |
97 | LIMK1 | 0.59036197 |
98 | TESK1 | 0.58591619 |
99 | MAPKAPK2 | 0.58052536 |
100 | INSRR | 0.57273110 |
101 | MAP3K8 | 0.57268468 |
102 | BMX | 0.56787394 |
103 | STK39 | 0.55085799 |
104 | CSNK1A1L | 0.54726952 |
105 | PRKACB | 0.53466791 |
106 | MAP3K14 | 0.52661940 |
107 | RIPK4 | 0.52175785 |
108 | PRKCD | 0.51717313 |
109 | ERBB4 | 0.50362854 |
110 | PRKACG | 0.50299908 |
111 | CDC42BPA | 0.50033136 |
112 | ILK | 0.49972245 |
113 | JAK1 | 0.47644762 |
114 | STK38L | 0.47469910 |
115 | WNK1 | 0.46602851 |
116 | NME2 | 0.46040659 |
117 | RPS6KA1 | 0.44712107 |
118 | PDK4 | 0.44708129 |
119 | PDK3 | 0.44708129 |
120 | PTK2 | 0.44272916 |
121 | PDGFRA | 0.42355534 |
122 | PRKG1 | 0.41795005 |
123 | DAPK3 | 0.41793811 |
124 | ITK | 0.41682477 |
125 | FGFR4 | 0.39332513 |
126 | IRAK4 | 0.38903136 |
127 | PAK2 | 0.38813640 |
128 | PRKCH | 0.38686229 |
129 | CSNK1G3 | 0.38434319 |
130 | IRAK1 | 0.37629319 |
131 | FER | 0.37578593 |
132 | MAP2K4 | 0.37392293 |
133 | CDK9 | 0.36713040 |
134 | CAMKK1 | 0.36006779 |
135 | TAOK1 | 0.35728833 |
136 | MAP3K6 | 0.35677490 |
137 | PDPK1 | 0.35493401 |
138 | SGK3 | 0.35029459 |
139 | CSNK1G2 | 0.34930419 |
140 | TNIK | 0.33776290 |
141 | DYRK1B | 0.33769962 |
142 | CSNK1G1 | 0.33187636 |
143 | PIK3CG | 0.32830312 |
144 | NTRK1 | 0.32025450 |
145 | DYRK3 | 0.32004725 |
146 | ALK | 0.31916294 |
147 | IGF1R | 0.31747954 |
148 | NEK6 | 0.31437988 |
149 | RPS6KA5 | 0.31374275 |
150 | CHUK | 0.30736590 |
151 | LYN | 0.29639526 |
152 | MAP3K5 | 0.28694091 |
153 | KDR | 0.27867999 |
154 | RPS6KA2 | 0.27563423 |
155 | TXK | 0.27366281 |
156 | PRKD1 | 0.27093319 |
157 | EPHB1 | 0.24749815 |
158 | NEK9 | 0.24707795 |
159 | PDK1 | 0.23814724 |
160 | CSK | 0.23730131 |
161 | MELK | 0.23245103 |
162 | MAPK12 | 0.22293708 |
163 | PRKCI | 0.21312325 |
164 | MAPK1 | 0.21066348 |
165 | ICK | 0.20441972 |
166 | GRK6 | 0.20176278 |
167 | RPS6KB1 | 0.19698056 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Pancreatic secretion_Homo sapiens_hsa04972 | 7.48256264 |
2 | Fat digestion and absorption_Homo sapiens_hsa04975 | 5.31795515 |
3 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 4.22805666 |
4 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 3.73612431 |
5 | * Protein digestion and absorption_Homo sapiens_hsa04974 | 3.70448155 |
6 | Renin-angiotensin system_Homo sapiens_hsa04614 | 3.66240422 |
7 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 3.07198183 |
8 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 2.91764221 |
9 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 2.53402072 |
10 | Mineral absorption_Homo sapiens_hsa04978 | 2.51800820 |
11 | PPAR signaling pathway_Homo sapiens_hsa03320 | 2.25503237 |
12 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 2.21114317 |
13 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.89023375 |
14 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 1.88835297 |
15 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 1.86397467 |
16 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 1.85713697 |
17 | Malaria_Homo sapiens_hsa05144 | 1.78550121 |
18 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.72824412 |
19 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.68031353 |
20 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.64677054 |
21 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 1.57685724 |
22 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.55290699 |
23 | Sulfur relay system_Homo sapiens_hsa04122 | 1.52634646 |
24 | Osteoclast differentiation_Homo sapiens_hsa04380 | 1.51292132 |
25 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.42445651 |
26 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 1.37221505 |
27 | Protein export_Homo sapiens_hsa03060 | 1.29611133 |
28 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 1.24869375 |
29 | Legionellosis_Homo sapiens_hsa05134 | 1.22980775 |
30 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.22830633 |
31 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.21386565 |
32 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.18077855 |
33 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.17526521 |
34 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.16338534 |
35 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 1.16204928 |
36 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 1.14781797 |
37 | Pertussis_Homo sapiens_hsa05133 | 1.08456191 |
38 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 1.06913139 |
39 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.05712131 |
40 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.01180333 |
41 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.99417738 |
42 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.96770388 |
43 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.96758423 |
44 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.95655483 |
45 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.94097923 |
46 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.91145948 |
47 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.90833968 |
48 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.90533841 |
49 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.90472083 |
50 | Influenza A_Homo sapiens_hsa05164 | 0.89182130 |
51 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.89135390 |
52 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.88927217 |
53 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.87740198 |
54 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.86910488 |
55 | Platelet activation_Homo sapiens_hsa04611 | 0.86668788 |
56 | Hepatitis C_Homo sapiens_hsa05160 | 0.86243224 |
57 | Other glycan degradation_Homo sapiens_hsa00511 | 0.85940553 |
58 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.85772833 |
59 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.85709282 |
60 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.85370390 |
61 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.84663108 |
62 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.82323249 |
63 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.80098621 |
64 | Salmonella infection_Homo sapiens_hsa05132 | 0.78758245 |
65 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.78128938 |
66 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.78048514 |
67 | Histidine metabolism_Homo sapiens_hsa00340 | 0.77192333 |
68 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.76654862 |
69 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.76596117 |
70 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.75814916 |
71 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.75221409 |
72 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.75017274 |
73 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.72050228 |
74 | Leishmaniasis_Homo sapiens_hsa05140 | 0.71934914 |
75 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.70773324 |
76 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.69519931 |
77 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.67841759 |
78 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.67187657 |
79 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.66576503 |
80 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.66548894 |
81 | Lysine degradation_Homo sapiens_hsa00310 | 0.65434189 |
82 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.59965224 |
83 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.59816272 |
84 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.59810817 |
85 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.59627382 |
86 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.55818479 |
87 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.55813871 |
88 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.55691298 |
89 | Endometrial cancer_Homo sapiens_hsa05213 | 0.53564443 |
90 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.53361569 |
91 | Apoptosis_Homo sapiens_hsa04210 | 0.53053095 |
92 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.52665969 |
93 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.52392873 |
94 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.49882420 |
95 | Prion diseases_Homo sapiens_hsa05020 | 0.49486265 |
96 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.49325434 |
97 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.49017654 |
98 | Colorectal cancer_Homo sapiens_hsa05210 | 0.48466788 |
99 | Adherens junction_Homo sapiens_hsa04520 | 0.48185092 |
100 | Phagosome_Homo sapiens_hsa04145 | 0.47967639 |
101 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.47797659 |
102 | Insulin secretion_Homo sapiens_hsa04911 | 0.47636986 |
103 | Retinol metabolism_Homo sapiens_hsa00830 | 0.47155645 |
104 | Tuberculosis_Homo sapiens_hsa05152 | 0.47056291 |
105 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.46760106 |
106 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.46182908 |
107 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.45578324 |
108 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.45219485 |
109 | Insulin resistance_Homo sapiens_hsa04931 | 0.44885091 |
110 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.44384515 |
111 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.44076838 |
112 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.43386968 |
113 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.42930617 |
114 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.42769851 |
115 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.42551780 |
116 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.41513366 |
117 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.39879506 |
118 | Peroxisome_Homo sapiens_hsa04146 | 0.39127855 |
119 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.38953339 |
120 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.38492257 |
121 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.38297515 |
122 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.37698530 |
123 | Carbon metabolism_Homo sapiens_hsa01200 | 0.37628261 |
124 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.37094089 |
125 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.36905959 |
126 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.36385402 |
127 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.35829722 |
128 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.34347116 |
129 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.34163874 |
130 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.33827085 |
131 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.33070168 |
132 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.32944329 |
133 | Hepatitis B_Homo sapiens_hsa05161 | 0.32766419 |
134 | Endocytosis_Homo sapiens_hsa04144 | 0.32679164 |
135 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.32463789 |
136 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.32075866 |
137 | Focal adhesion_Homo sapiens_hsa04510 | 0.31022124 |
138 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.30679672 |
139 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.30171902 |
140 | Galactose metabolism_Homo sapiens_hsa00052 | 0.29819545 |
141 | Amoebiasis_Homo sapiens_hsa05146 | 0.29687817 |
142 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.28815306 |
143 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.28302449 |
144 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.27592980 |
145 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.27201312 |
146 | Glioma_Homo sapiens_hsa05214 | 0.27078352 |
147 | Prostate cancer_Homo sapiens_hsa05215 | 0.26273731 |
148 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.24877894 |
149 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.24801442 |
150 | Bile secretion_Homo sapiens_hsa04976 | 0.24247005 |
151 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.24119407 |
152 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.23807356 |
153 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.23313947 |
154 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.22704329 |
155 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.20290820 |
156 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.19898731 |
157 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.19851188 |
158 | Lysosome_Homo sapiens_hsa04142 | 0.19222116 |
159 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.18137078 |
160 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.17903201 |
161 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.17743561 |
162 | Tight junction_Homo sapiens_hsa04530 | 0.17742371 |