Rank | Gene Set | Z-score |
---|---|---|
1 | DNA unwinding involved in DNA replication (GO:0006268) | 5.68684541 |
2 | establishment of viral latency (GO:0019043) | 5.03016740 |
3 | folic acid-containing compound biosynthetic process (GO:0009396) | 4.96065613 |
4 | IMP biosynthetic process (GO:0006188) | 4.90605320 |
5 | protein localization to kinetochore (GO:0034501) | 4.61249500 |
6 | nuclear pore organization (GO:0006999) | 4.55197718 |
7 | formation of translation preinitiation complex (GO:0001731) | 4.51796313 |
8 | L-serine metabolic process (GO:0006563) | 4.44356575 |
9 | DNA strand elongation involved in DNA replication (GO:0006271) | 4.43633204 |
10 | peptidyl-arginine omega-N-methylation (GO:0035247) | 4.40745037 |
11 | IMP metabolic process (GO:0046040) | 4.39783060 |
12 | regulation of translational termination (GO:0006449) | 4.36732722 |
13 | mitotic nuclear envelope disassembly (GO:0007077) | 4.34843382 |
14 | nucleobase biosynthetic process (GO:0046112) | 4.32033731 |
15 | DNA replication initiation (GO:0006270) | 4.23594092 |
16 | ribosome assembly (GO:0042255) | 4.19573238 |
17 | nuclear pore complex assembly (GO:0051292) | 4.17947910 |
18 | membrane disassembly (GO:0030397) | 4.13549929 |
19 | nuclear envelope disassembly (GO:0051081) | 4.13549929 |
20 | regulation of translational fidelity (GO:0006450) | 4.12862286 |
21 | DNA strand elongation (GO:0022616) | 4.12402869 |
22 | histone arginine methylation (GO:0034969) | 4.00483143 |
23 | purine nucleobase biosynthetic process (GO:0009113) | 3.91026624 |
24 | proline biosynthetic process (GO:0006561) | 3.86033700 |
25 | peptidyl-arginine methylation (GO:0018216) | 3.83123422 |
26 | peptidyl-arginine N-methylation (GO:0035246) | 3.83123422 |
27 | mitotic metaphase plate congression (GO:0007080) | 3.78241728 |
28 | heterochromatin organization (GO:0070828) | 3.72947297 |
29 | DNA replication-dependent nucleosome assembly (GO:0006335) | 3.72854429 |
30 | DNA replication-dependent nucleosome organization (GO:0034723) | 3.72854429 |
31 | telomere maintenance via semi-conservative replication (GO:0032201) | 3.71898127 |
32 | regulation of gene silencing by RNA (GO:0060966) | 3.68094457 |
33 | regulation of posttranscriptional gene silencing (GO:0060147) | 3.68094457 |
34 | regulation of gene silencing by miRNA (GO:0060964) | 3.68094457 |
35 | regulation of protein heterodimerization activity (GO:0043497) | 3.66436940 |
36 | cellular protein complex localization (GO:0034629) | 3.61906935 |
37 | protein localization to chromosome, centromeric region (GO:0071459) | 3.60456966 |
38 | mitotic G1 DNA damage checkpoint (GO:0031571) | 3.58773657 |
39 | pentose-phosphate shunt (GO:0006098) | 3.55971303 |
40 | mitotic sister chromatid segregation (GO:0000070) | 3.49697521 |
41 | ribosomal large subunit biogenesis (GO:0042273) | 3.46224030 |
42 | ribosome biogenesis (GO:0042254) | 3.46111712 |
43 | establishment of integrated proviral latency (GO:0075713) | 3.41602656 |
44 | nuclear envelope reassembly (GO:0031468) | 3.40994839 |
45 | mitotic nuclear envelope reassembly (GO:0007084) | 3.40994839 |
46 | tRNA aminoacylation for protein translation (GO:0006418) | 3.28740800 |
47 | DNA replication checkpoint (GO:0000076) | 3.27674235 |
48 | sister chromatid segregation (GO:0000819) | 3.26917257 |
49 | regulation of attachment of spindle microtubules to kinetochore (GO:0051988) | 3.22984515 |
50 | nucleobase-containing small molecule interconversion (GO:0015949) | 3.21484618 |
51 | nuclear envelope organization (GO:0006998) | 3.19375482 |
52 | negative regulation of ligase activity (GO:0051352) | 3.18673030 |
53 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.18673030 |
54 | telomere maintenance via recombination (GO:0000722) | 3.18181284 |
55 | amino acid activation (GO:0043038) | 3.16925431 |
56 | tRNA aminoacylation (GO:0043039) | 3.16925431 |
57 | pre-miRNA processing (GO:0031054) | 3.15345850 |
58 | de novo protein folding (GO:0006458) | 3.12824320 |
59 | DNA duplex unwinding (GO:0032508) | 3.12696755 |
60 | DNA geometric change (GO:0032392) | 3.11876777 |
61 | telomere maintenance via telomere lengthening (GO:0010833) | 3.10932023 |
62 | chaperone-mediated protein complex assembly (GO:0051131) | 3.10352258 |
63 | NADPH regeneration (GO:0006740) | 3.08692374 |
64 | mitotic recombination (GO:0006312) | 3.08430346 |
65 | protein complex localization (GO:0031503) | 3.05243101 |
66 | * glycolytic process (GO:0006096) | 3.04688028 |
67 | peptidyl-lysine dimethylation (GO:0018027) | 3.02964823 |
68 | pore complex assembly (GO:0046931) | 3.02525400 |
69 | de novo posttranslational protein folding (GO:0051084) | 3.02475781 |
70 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.02057895 |
71 | metaphase plate congression (GO:0051310) | 3.01796746 |
72 | maintenance of protein localization in endoplasmic reticulum (GO:0035437) | 3.00548030 |
73 | regulation of centrosome cycle (GO:0046605) | 3.00083312 |
74 | mitochondrial fragmentation involved in apoptotic process (GO:0043653) | 2.97982967 |
75 | cell cycle G1/S phase transition (GO:0044843) | 2.97773536 |
76 | G1/S transition of mitotic cell cycle (GO:0000082) | 2.97773536 |
77 | negative regulation of mRNA splicing, via spliceosome (GO:0048025) | 2.97739011 |
78 | protein retention in ER lumen (GO:0006621) | 2.97050002 |
79 | COPI coating of Golgi vesicle (GO:0048205) | 2.96832729 |
80 | Golgi transport vesicle coating (GO:0048200) | 2.96832729 |
81 | mitotic G1/S transition checkpoint (GO:0044819) | 2.96811195 |
82 | regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083) | 2.95695903 |
83 | snRNA processing (GO:0016180) | 2.94506522 |
84 | mitochondrial fusion (GO:0008053) | 2.94254406 |
85 | serine family amino acid biosynthetic process (GO:0009070) | 2.93938734 |
86 | glucose 6-phosphate metabolic process (GO:0051156) | 2.92877687 |
87 | translational initiation (GO:0006413) | 2.91451395 |
88 | regulation of spindle organization (GO:0090224) | 2.89137687 |
89 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 2.88611326 |
90 | retrograde vesicle-mediated transport, Golgi to ER (GO:0006890) | 2.87794093 |
91 | deoxyribonucleotide biosynthetic process (GO:0009263) | 2.86551029 |
92 | maturation of SSU-rRNA (GO:0030490) | 2.86076224 |
93 | nucleotide-excision repair, DNA gap filling (GO:0006297) | 2.85091938 |
94 | spliceosomal snRNP assembly (GO:0000387) | 2.84031210 |
95 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.83517601 |
96 | regulation of mammary gland epithelial cell proliferation (GO:0033599) | 2.83348781 |
97 | regulation of mitochondrial translation (GO:0070129) | 2.82476761 |
98 | establishment of chromosome localization (GO:0051303) | 2.81759719 |
99 | postreplication repair (GO:0006301) | 2.79754466 |
100 | G1 DNA damage checkpoint (GO:0044783) | 2.78996610 |
101 | positive regulation of chromosome segregation (GO:0051984) | 2.77597591 |
102 | mitotic chromosome condensation (GO:0007076) | 2.76474738 |
103 | histone-serine phosphorylation (GO:0035404) | 2.76445712 |
104 | 4-hydroxyproline metabolic process (GO:0019471) | 2.75550462 |
105 | attachment of spindle microtubules to kinetochore (GO:0008608) | 2.75289954 |
106 | tricarboxylic acid cycle (GO:0006099) | 2.75040452 |
107 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 2.74573866 |
108 | protein maturation by protein folding (GO:0022417) | 2.72647800 |
109 | translational elongation (GO:0006414) | 2.72533462 |
110 | spliceosomal tri-snRNP complex assembly (GO:0000244) | 2.72525440 |
111 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.71699989 |
112 | negative regulation of mitotic sister chromatid separation (GO:2000816) | 2.69490809 |
113 | negative regulation of sister chromatid segregation (GO:0033046) | 2.69490809 |
114 | negative regulation of mitotic metaphase/anaphase transition (GO:0045841) | 2.69490809 |
115 | negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100) | 2.69490809 |
116 | negative regulation of mitotic sister chromatid segregation (GO:0033048) | 2.69490809 |
117 | base-excision repair (GO:0006284) | 2.69225176 |
118 | double-strand break repair via nonhomologous end joining (GO:0006303) | 2.68744197 |
119 | non-recombinational repair (GO:0000726) | 2.68744197 |
120 | glucocorticoid receptor signaling pathway (GO:0042921) | 2.68727800 |
121 | snRNA metabolic process (GO:0016073) | 2.67707952 |
122 | protein export from nucleus (GO:0006611) | 2.67409035 |
123 | regulation of ubiquitin-protein transferase activity (GO:0051438) | 2.65606132 |
124 | spindle checkpoint (GO:0031577) | 2.65478258 |
125 | regulation of mitotic spindle organization (GO:0060236) | 2.65365768 |
126 | proteasome assembly (GO:0043248) | 2.64101541 |
127 | DNA damage response, detection of DNA damage (GO:0042769) | 2.63971658 |
128 | pteridine-containing compound biosynthetic process (GO:0042559) | 2.63294225 |
129 | regulation of centriole replication (GO:0046599) | 2.63014526 |
130 | regulation of translational elongation (GO:0006448) | 2.62763600 |
131 | translational termination (GO:0006415) | 2.62339546 |
132 | regulation of chromosome segregation (GO:0051983) | 2.62241599 |
133 | negative regulation of chromosome segregation (GO:0051985) | 2.62099385 |
134 | mitotic spindle checkpoint (GO:0071174) | 2.61722562 |
135 | pseudouridine synthesis (GO:0001522) | 2.61439689 |
136 | mitotic spindle assembly checkpoint (GO:0007094) | 2.60170406 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 7.84935503 |
2 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 4.55662030 |
3 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 4.46152228 |
4 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 4.16723043 |
5 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 3.25433665 |
6 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 3.12563073 |
7 | * MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.83996167 |
8 | * MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.81609766 |
9 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 2.72185689 |
10 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.55382773 |
11 | XRN2_22483619_ChIP-Seq_HELA_Human | 2.46407338 |
12 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 2.43387490 |
13 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.43089747 |
14 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.38328982 |
15 | * POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 2.30777724 |
16 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.29449740 |
17 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.20817635 |
18 | AR_21909140_ChIP-Seq_LNCAP_Human | 2.19268296 |
19 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.17338713 |
20 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.16803349 |
21 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 2.06217366 |
22 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.98060712 |
23 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.93906211 |
24 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.85937950 |
25 | * MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.85245394 |
26 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.85049215 |
27 | * DCP1A_22483619_ChIP-Seq_HELA_Human | 1.84520444 |
28 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.79291724 |
29 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 1.78347939 |
30 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 1.77285232 |
31 | MYC_22102868_ChIP-Seq_BL_Human | 1.75799733 |
32 | * KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.74295051 |
33 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.72076763 |
34 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.71912971 |
35 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.71625677 |
36 | * GABP_19822575_ChIP-Seq_HepG2_Human | 1.70157741 |
37 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.68569827 |
38 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.68229573 |
39 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 1.59680727 |
40 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.56205442 |
41 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.55338102 |
42 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.52706464 |
43 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.52557697 |
44 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.52491052 |
45 | * PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.52064075 |
46 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.50405295 |
47 | * HIF1A_21447827_ChIP-Seq_MCF-7_Human | 1.49819565 |
48 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 1.48957929 |
49 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.48281961 |
50 | * KDM5A_27292631_Chip-Seq_BREAST_Human | 1.46922037 |
51 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 1.46007394 |
52 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.43937367 |
53 | * DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.42461308 |
54 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 1.41918483 |
55 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.40448838 |
56 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.38905408 |
57 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.38265614 |
58 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.38233038 |
59 | ZIC3_20872845_ChIP-ChIP_MESCs_Mouse | 1.38192898 |
60 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.38069005 |
61 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 1.35810669 |
62 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.34018819 |
63 | * ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.29204796 |
64 | * ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.27833775 |
65 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.26988637 |
66 | * CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.25955742 |
67 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 1.23107719 |
68 | ATF3_27146783_Chip-Seq_COLON_Human | 1.22600149 |
69 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 1.22484288 |
70 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.22316319 |
71 | SREBP1_19666523_ChIP-Seq_LIVER_Mouse | 1.21712256 |
72 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 1.20855493 |
73 | * E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.20438200 |
74 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 1.20134711 |
75 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.19901391 |
76 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.19172251 |
77 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.16566874 |
78 | TCF3_18692474_ChIP-Seq_MEFs_Mouse | 1.14640759 |
79 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.14378193 |
80 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.14211258 |
81 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.14020396 |
82 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.13734422 |
83 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.13199641 |
84 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.12962179 |
85 | OCT4_18692474_ChIP-Seq_MEFs_Mouse | 1.12368433 |
86 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 1.10108978 |
87 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 1.09144700 |
88 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.08797978 |
89 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.07750778 |
90 | * CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.07540919 |
91 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.06216160 |
92 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 1.05842042 |
93 | * SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.05818578 |
94 | TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.04892813 |
95 | * SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.03600992 |
96 | TRIM28_19339689_ChIP-ChIP_MESCs_Mouse | 1.03542661 |
97 | SOX17_20123909_ChIP-Seq_XEN_Mouse | 1.02692253 |
98 | TCFCP2L1_18555785_ChIP-Seq_MESCs_Mouse | 1.02502515 |
99 | SALL4_18804426_ChIP-ChIP_MESCs_Mouse | 1.01434178 |
100 | * NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 1.01140476 |
101 | NANOG_21062744_ChIP-ChIP_HESCs_Human | 1.00304490 |
102 | * SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 0.99448398 |
103 | NACC1_18358816_ChIP-ChIP_MESCs_Mouse | 0.98865992 |
104 | TBX5_21415370_ChIP-Seq_HL-1_Mouse | 0.98665718 |
105 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 0.97196675 |
106 | * ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 0.96406668 |
107 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 0.96025583 |
108 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 0.94088626 |
109 | SOX2_18692474_ChIP-Seq_MEFs_Mouse | 0.93684104 |
110 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 0.92646547 |
111 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 0.92023940 |
112 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.91776631 |
113 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 0.91370741 |
114 | * CHD1_26751641_Chip-Seq_LNCaP_Human | 0.90570114 |
115 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.90473107 |
116 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 0.90085864 |
117 | EOMES_20176728_ChIP-ChIP_TSCs_Mouse | 0.89879204 |
118 | SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 0.89623587 |
119 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 0.89576135 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0010352_gastrointestinal_tract_polyps | 3.94128192 |
2 | MP0004957_abnormal_blastocyst_morpholog | 3.69416083 |
3 | MP0003705_abnormal_hypodermis_morpholog | 3.69202899 |
4 | MP0003693_abnormal_embryo_hatching | 3.64498387 |
5 | MP0003123_paternal_imprinting | 3.57484476 |
6 | MP0003111_abnormal_nucleus_morphology | 3.43715586 |
7 | MP0010030_abnormal_orbit_morphology | 3.13839403 |
8 | MP0010094_abnormal_chromosome_stability | 3.05623310 |
9 | MP0003077_abnormal_cell_cycle | 3.01171814 |
10 | MP0003941_abnormal_skin_development | 2.79402311 |
11 | MP0001730_embryonic_growth_arrest | 2.70395548 |
12 | MP0008932_abnormal_embryonic_tissue | 2.50001921 |
13 | MP0004233_abnormal_muscle_weight | 2.47914909 |
14 | MP0010307_abnormal_tumor_latency | 2.38852687 |
15 | MP0000537_abnormal_urethra_morphology | 2.28951249 |
16 | MP0000350_abnormal_cell_proliferation | 2.18369607 |
17 | MP0005076_abnormal_cell_differentiation | 2.11984111 |
18 | MP0004272_abnormal_basement_membrane | 2.10114642 |
19 | MP0003283_abnormal_digestive_organ | 2.01774607 |
20 | MP0001697_abnormal_embryo_size | 1.96010514 |
21 | MP0010234_abnormal_vibrissa_follicle | 1.91329997 |
22 | MP0004133_heterotaxia | 1.89211681 |
23 | MP0008260_abnormal_autophagy | 1.86536232 |
24 | MP0008007_abnormal_cellular_replicative | 1.86278842 |
25 | MP0004197_abnormal_fetal_growth/weight/ | 1.86102635 |
26 | MP0002084_abnormal_developmental_patter | 1.80119163 |
27 | MP0005380_embryogenesis_phenotype | 1.77609421 |
28 | MP0001672_abnormal_embryogenesis/_devel | 1.77609421 |
29 | MP0002080_prenatal_lethality | 1.76348380 |
30 | MP0003984_embryonic_growth_retardation | 1.75329612 |
31 | MP0002088_abnormal_embryonic_growth/wei | 1.70812231 |
32 | MP0005501_abnormal_skin_physiology | 1.69645908 |
33 | MP0002796_impaired_skin_barrier | 1.69299119 |
34 | MP0000358_abnormal_cell_content/ | 1.67565263 |
35 | MP0002085_abnormal_embryonic_tissue | 1.66433805 |
36 | MP0003121_genomic_imprinting | 1.63729654 |
37 | MP0008057_abnormal_DNA_replication | 1.60840687 |
38 | MP0003221_abnormal_cardiomyocyte_apopto | 1.57804142 |
39 | MP0003890_abnormal_embryonic-extraembry | 1.57466104 |
40 | MP0002877_abnormal_melanocyte_morpholog | 1.54912599 |
41 | MP0002086_abnormal_extraembryonic_tissu | 1.49440448 |
42 | MP0003172_abnormal_lysosome_physiology | 1.48137188 |
43 | MP0003566_abnormal_cell_adhesion | 1.46074247 |
44 | MP0009053_abnormal_anal_canal | 1.44358125 |
45 | MP0003119_abnormal_digestive_system | 1.42042702 |
46 | MP0002254_reproductive_system_inflammat | 1.40795326 |
47 | MP0003315_abnormal_perineum_morphology | 1.40224377 |
48 | MP0008058_abnormal_DNA_repair | 1.40066669 |
49 | MP0001299_abnormal_eye_distance/ | 1.36107353 |
50 | MP0001293_anophthalmia | 1.34063058 |
51 | MP0001346_abnormal_lacrimal_gland | 1.33631393 |
52 | MP0005023_abnormal_wound_healing | 1.33604492 |
53 | MP0003567_abnormal_fetal_cardiomyocyte | 1.32282271 |
54 | MP0005623_abnormal_meninges_morphology | 1.30558627 |
55 | MP0003122_maternal_imprinting | 1.29557968 |
56 | MP0001529_abnormal_vocalization | 1.26876150 |
57 | MP0004858_abnormal_nervous_system | 1.26773300 |
58 | MP0002234_abnormal_pharynx_morphology | 1.25636406 |
59 | MP0002653_abnormal_ependyma_morphology | 1.25241713 |
60 | MP0000579_abnormal_nail_morphology | 1.22234211 |
61 | MP0003786_premature_aging | 1.20153223 |
62 | MP0004084_abnormal_cardiac_muscle | 1.15230552 |
63 | MP0008877_abnormal_DNA_methylation | 1.14860910 |
64 | MP0005394_taste/olfaction_phenotype | 1.13085000 |
65 | MP0005499_abnormal_olfactory_system | 1.13085000 |
66 | MP0005451_abnormal_body_composition | 1.12355507 |
67 | MP0009672_abnormal_birth_weight | 1.11449448 |
68 | MP0006072_abnormal_retinal_apoptosis | 1.11219939 |
69 | MP0000534_abnormal_ureter_morphology | 1.10937553 |
70 | MP0003942_abnormal_urinary_system | 1.09969689 |
71 | MP0000858_altered_metastatic_potential | 1.09869243 |
72 | MP0001348_abnormal_lacrimal_gland | 1.09739087 |
73 | MP0000313_abnormal_cell_death | 1.09659112 |
74 | MP0005384_cellular_phenotype | 1.09634407 |
75 | MP0003385_abnormal_body_wall | 1.04183951 |
76 | MP0000762_abnormal_tongue_morphology | 1.03039275 |
77 | MP0000750_abnormal_muscle_regeneration | 1.02366432 |
78 | MP0005248_abnormal_Harderian_gland | 1.02009859 |
79 | MP0003937_abnormal_limbs/digits/tail_de | 1.00970913 |
80 | MP0002269_muscular_atrophy | 1.00255689 |
81 | MP0001849_ear_inflammation | 0.96015641 |
82 | MP0005621_abnormal_cell_physiology | 0.96013033 |
83 | MP0003718_maternal_effect | 0.93048160 |
84 | MP0003115_abnormal_respiratory_system | 0.90362814 |
85 | MP0003186_abnormal_redox_activity | 0.90149878 |
86 | MP0002019_abnormal_tumor_incidence | 0.89868820 |
87 | MP0004859_abnormal_synaptic_plasticity | 0.89442550 |
88 | MP0002060_abnormal_skin_morphology | 0.89220697 |
89 | MP0009697_abnormal_copulation | 0.89071479 |
90 | MP0002111_abnormal_tail_morphology | 0.89049502 |
91 | MP0000428_abnormal_craniofacial_morphol | 0.88939309 |
92 | MP0001915_intracranial_hemorrhage | 0.88682953 |
93 | MP0002089_abnormal_postnatal_growth/wei | 0.86858715 |
94 | MP0000490_abnormal_crypts_of | 0.86312006 |
95 | MP0003303_peritoneal_inflammation | 0.84997802 |
96 | MP0001661_extended_life_span | 0.84710496 |
97 | MP0002090_abnormal_vision | 0.84333697 |
98 | MP0008770_decreased_survivor_rate | 0.83565229 |
99 | MP0003453_abnormal_keratinocyte_physiol | 0.83129819 |
100 | MP0005257_abnormal_intraocular_pressure | 0.82370406 |
101 | MP0002751_abnormal_autonomic_nervous | 0.81378027 |
102 | MP0003806_abnormal_nucleotide_metabolis | 0.80310634 |
103 | MP0000733_abnormal_muscle_development | 0.79580575 |
104 | MP0002092_abnormal_eye_morphology | 0.76383519 |
105 | MP0000751_myopathy | 0.75598704 |
106 | MP0003861_abnormal_nervous_system | 0.72137348 |
107 | MP0003329_amyloid_beta_deposits | 0.72123266 |
108 | MP0005266_abnormal_metabolism | 0.72034866 |
109 | MP0006035_abnormal_mitochondrial_morpho | 0.71512188 |
110 | MP0004808_abnormal_hematopoietic_stem | 0.70561418 |
111 | MP0001216_abnormal_epidermal_layer | 0.69001666 |
112 | MP0002233_abnormal_nose_morphology | 0.68468201 |
113 | MP0009703_decreased_birth_body | 0.67635129 |
114 | MP0001188_hyperpigmentation | 0.66904307 |
115 | MP0005391_vision/eye_phenotype | 0.66775388 |
116 | MP0005193_abnormal_anterior_eye | 0.66618957 |
117 | MP0001286_abnormal_eye_development | 0.66428114 |
118 | MP0000747_muscle_weakness | 0.65836864 |
119 | MP0000371_diluted_coat_color | 0.65154334 |
120 | MP0002697_abnormal_eye_size | 0.64777808 |
121 | MP0008438_abnormal_cutaneous_collagen | 0.64441991 |
122 | MP0003091_abnormal_cell_migration | 0.64393524 |
123 | MP0004185_abnormal_adipocyte_glucose | 0.64034577 |
124 | MP0001340_abnormal_eyelid_morphology | 0.63985407 |
125 | MP0000566_synostosis | 0.63675108 |
126 | MP0003448_altered_tumor_morphology | 0.61763368 |
127 | MP0002925_abnormal_cardiovascular_devel | 0.61206863 |
128 | MP0005197_abnormal_uvea_morphology | 0.60519007 |
129 | MP0002332_abnormal_exercise_endurance | 0.60347272 |
130 | MP0000266_abnormal_heart_morphology | 0.58600224 |
131 | MP0002282_abnormal_trachea_morphology | 0.58369957 |
132 | MP0001727_abnormal_embryo_implantation | 0.57958820 |
133 | MP0005551_abnormal_eye_electrophysiolog | 0.56706643 |
134 | MP0001324_abnormal_eye_pigmentation | 0.56380698 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Ependymoma (HP:0002888) | 4.07601528 |
2 | Cortical dysplasia (HP:0002539) | 3.84853861 |
3 | Selective tooth agenesis (HP:0001592) | 3.40125644 |
4 | Agnosia (HP:0010524) | 3.32140745 |
5 | Premature rupture of membranes (HP:0001788) | 3.30146010 |
6 | Angiofibromas (HP:0010615) | 3.17140381 |
7 | Adenoma sebaceum (HP:0009720) | 3.17140381 |
8 | Abnormality of the astrocytes (HP:0100707) | 3.13274997 |
9 | Astrocytoma (HP:0009592) | 3.13274997 |
10 | Abnormality of the anterior horn cell (HP:0006802) | 3.01488895 |
11 | Degeneration of anterior horn cells (HP:0002398) | 3.01488895 |
12 | Colon cancer (HP:0003003) | 2.99847796 |
13 | Congenital stationary night blindness (HP:0007642) | 2.95038910 |
14 | Birth length less than 3rd percentile (HP:0003561) | 2.82860299 |
15 | Hand muscle atrophy (HP:0009130) | 2.74575671 |
16 | Insomnia (HP:0100785) | 2.73911421 |
17 | Long palpebral fissure (HP:0000637) | 2.64221396 |
18 | Microvesicular hepatic steatosis (HP:0001414) | 2.63722301 |
19 | Upper limb muscle weakness (HP:0003484) | 2.63713573 |
20 | Abnormal number of incisors (HP:0011064) | 2.57800107 |
21 | Medulloblastoma (HP:0002885) | 2.50889611 |
22 | Trismus (HP:0000211) | 2.48045750 |
23 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 2.47573422 |
24 | Abnormality of the labia minora (HP:0012880) | 2.44690205 |
25 | Deviation of the thumb (HP:0009603) | 2.43263389 |
26 | Basal cell carcinoma (HP:0002671) | 2.40040599 |
27 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.35498003 |
28 | Exercise-induced muscle cramps (HP:0003710) | 2.35175408 |
29 | Distal upper limb amyotrophy (HP:0007149) | 2.33569237 |
30 | Upper limb amyotrophy (HP:0009129) | 2.33569237 |
31 | Progressive external ophthalmoplegia (HP:0000590) | 2.32278691 |
32 | Abnormality of glycolysis (HP:0004366) | 2.31035896 |
33 | Increased serum pyruvate (HP:0003542) | 2.31035896 |
34 | Severe visual impairment (HP:0001141) | 2.30459799 |
35 | Proximal placement of thumb (HP:0009623) | 2.29961894 |
36 | Genu recurvatum (HP:0002816) | 2.29815534 |
37 | Abnormality of the umbilical cord (HP:0010881) | 2.29668155 |
38 | Glioma (HP:0009733) | 2.28054764 |
39 | Spastic diplegia (HP:0001264) | 2.25816238 |
40 | Missing ribs (HP:0000921) | 2.25235487 |
41 | Cutaneous melanoma (HP:0012056) | 2.24090938 |
42 | Stenosis of the external auditory canal (HP:0000402) | 2.23535109 |
43 | Atrophy/Degeneration involving motor neurons (HP:0007373) | 2.22058711 |
44 | Increased nuchal translucency (HP:0010880) | 2.21826510 |
45 | Abdominal situs inversus (HP:0003363) | 2.20778735 |
46 | Abnormality of abdominal situs (HP:0011620) | 2.20778735 |
47 | Neoplasm of the pancreas (HP:0002894) | 2.20460633 |
48 | Renal duplication (HP:0000075) | 2.18717891 |
49 | Overriding aorta (HP:0002623) | 2.18301267 |
50 | Pointed chin (HP:0000307) | 2.16000571 |
51 | Chromsome breakage (HP:0040012) | 2.15899624 |
52 | Pelvic girdle muscle weakness (HP:0003749) | 2.14269770 |
53 | Shoulder girdle muscle weakness (HP:0003547) | 2.13979230 |
54 | Ovarian neoplasm (HP:0100615) | 2.13643266 |
55 | Oral leukoplakia (HP:0002745) | 2.12162880 |
56 | Cerebral hypomyelination (HP:0006808) | 2.10820872 |
57 | Multiple enchondromatosis (HP:0005701) | 2.10637673 |
58 | Hyperacusis (HP:0010780) | 2.08845560 |
59 | Deep palmar crease (HP:0006191) | 2.08793894 |
60 | Neuroblastoma (HP:0003006) | 2.08363018 |
61 | Primitive neuroectodermal tumor (HP:0030065) | 2.08363018 |
62 | Neuroblastic tumors (HP:0004376) | 2.08363018 |
63 | Peripheral primitive neuroectodermal neoplasm (HP:0030067) | 2.08363018 |
64 | Reticulocytopenia (HP:0001896) | 2.08162699 |
65 | Increased density of long bones (HP:0006392) | 2.08159515 |
66 | Protrusio acetabuli (HP:0003179) | 2.08110196 |
67 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.06590230 |
68 | Generalized hypotonia (HP:0001290) | 2.06306906 |
69 | Ragged-red muscle fibers (HP:0003200) | 2.05223412 |
70 | Ankle contracture (HP:0006466) | 2.04530566 |
71 | Horseshoe kidney (HP:0000085) | 2.03961109 |
72 | Metaphyseal cupping (HP:0003021) | 2.03926364 |
73 | Breast hypoplasia (HP:0003187) | 2.03723657 |
74 | Postnatal microcephaly (HP:0005484) | 2.03203006 |
75 | Aplasia/hypoplasia of the humerus (HP:0006507) | 2.02639898 |
76 | Rhabdomyolysis (HP:0003201) | 2.02258707 |
77 | Progressive muscle weakness (HP:0003323) | 1.99563475 |
78 | Slender long bone (HP:0003100) | 1.99535901 |
79 | Cholecystitis (HP:0001082) | 1.99316312 |
80 | Abnormal gallbladder physiology (HP:0012438) | 1.99316312 |
81 | Fibroma (HP:0010614) | 1.98881477 |
82 | Absent thumb (HP:0009777) | 1.98200349 |
83 | Rhabdomyosarcoma (HP:0002859) | 1.98174464 |
84 | Ankyloglossia (HP:0010296) | 1.98038790 |
85 | Facial cleft (HP:0002006) | 1.95929936 |
86 | Intestinal polyp (HP:0005266) | 1.94756407 |
87 | Hypoplasia of the capital femoral epiphysis (HP:0003090) | 1.94520404 |
88 | Broad distal phalanx of finger (HP:0009836) | 1.93870929 |
89 | Intestinal polyposis (HP:0200008) | 1.93209050 |
90 | Abnormality of the lower motor neuron (HP:0002366) | 1.93086358 |
91 | Rough bone trabeculation (HP:0100670) | 1.92970898 |
92 | Vertebral compression fractures (HP:0002953) | 1.92748572 |
93 | Diminished motivation (HP:0000745) | 1.91546423 |
94 | Abnormal lung lobation (HP:0002101) | 1.91265290 |
95 | Freckling (HP:0001480) | 1.91018089 |
96 | Abnormal neuron morphology (HP:0012757) | 1.90712111 |
97 | Abnormality of the motor neurons (HP:0002450) | 1.90712111 |
98 | Atresia of the external auditory canal (HP:0000413) | 1.89893421 |
99 | Trigonocephaly (HP:0000243) | 1.89410369 |
100 | Short humerus (HP:0005792) | 1.87918795 |
101 | Bowel diverticulosis (HP:0005222) | 1.87908067 |
102 | Fibrous tissue neoplasm (HP:0012316) | 1.87655504 |
103 | Spinal cord compression (HP:0002176) | 1.86908587 |
104 | Annular pancreas (HP:0001734) | 1.85071837 |
105 | Abnormality of the calcaneus (HP:0008364) | 1.84986574 |
106 | Biliary tract neoplasm (HP:0100574) | 1.84210487 |
107 | Glossoptosis (HP:0000162) | 1.83016419 |
108 | Abnormality of the fetal cardiovascular system (HP:0010948) | 1.82712383 |
109 | Abnormal umbilical cord blood vessels (HP:0011403) | 1.82712383 |
110 | Single umbilical artery (HP:0001195) | 1.82712383 |
111 | Termporal pattern (HP:0011008) | 1.82437614 |
112 | Insidious onset (HP:0003587) | 1.82437614 |
113 | Cholelithiasis (HP:0001081) | 1.81498722 |
114 | Apathy (HP:0000741) | 1.79901984 |
115 | Achilles tendon contracture (HP:0001771) | 1.78525610 |
116 | Abnormalities of placenta or umbilical cord (HP:0001194) | 1.78516066 |
117 | Cervical subluxation (HP:0003308) | 1.77115110 |
118 | Abnormality of oral frenula (HP:0000190) | 1.76781776 |
119 | Gout (HP:0001997) | 1.75935832 |
120 | Microretrognathia (HP:0000308) | 1.75655477 |
121 | Neoplasm of the colon (HP:0100273) | 1.75318069 |
122 | Spinal muscular atrophy (HP:0007269) | 1.75224415 |
123 | Neoplasm of the adrenal gland (HP:0100631) | 1.75076431 |
124 | Aplasia/Hypoplasia of the vertebrae (HP:0008515) | 1.71783695 |
125 | Vertebral hypoplasia (HP:0008417) | 1.71783695 |
126 | Abnormality of the musculature of the pelvis (HP:0001469) | 1.71753786 |
127 | Abnormality of the hip-girdle musculature (HP:0001445) | 1.71753786 |
128 | Microglossia (HP:0000171) | 1.71513424 |
129 | Abnormality of macular pigmentation (HP:0008002) | 1.71315719 |
130 | Secondary amenorrhea (HP:0000869) | 1.70114457 |
131 | Abnormality of pain sensation (HP:0010832) | 1.69362548 |
132 | Impaired pain sensation (HP:0007328) | 1.69362548 |
133 | High anterior hairline (HP:0009890) | 1.67194047 |
134 | Choanal stenosis (HP:0000452) | 1.67186523 |
135 | Meckel diverticulum (HP:0002245) | 1.67030085 |
136 | Duplication of thumb phalanx (HP:0009942) | 1.66970091 |
137 | Prominent metopic ridge (HP:0005487) | 1.66655310 |
138 | Back pain (HP:0003418) | 1.65781869 |
139 | Absent radius (HP:0003974) | 1.63897012 |
140 | Nephroblastoma (Wilms tumor) (HP:0002667) | 1.63805939 |
141 | Decreased number of large peripheral myelinated nerve fibers (HP:0003387) | 1.62047069 |
142 | Abnormal trabecular bone morphology (HP:0100671) | 1.61268792 |
143 | Abnormal gallbladder morphology (HP:0012437) | 1.60315858 |
144 | Lower limb amyotrophy (HP:0007210) | 1.59925463 |
145 | Entropion (HP:0000621) | 1.59245461 |
146 | Hypoplastic pelvis (HP:0008839) | 1.59057002 |
147 | Hammertoe (HP:0001765) | 1.58947699 |
148 | Absent forearm bone (HP:0003953) | 1.58807508 |
149 | Aplasia involving forearm bones (HP:0009822) | 1.58807508 |
150 | Squamous cell carcinoma (HP:0002860) | 1.58270725 |
151 | Pterygium (HP:0001059) | 1.57643182 |
152 | Reduced antithrombin III activity (HP:0001976) | 1.57188245 |
153 | Elfin facies (HP:0004428) | 1.56409448 |
154 | Progressive hearing impairment (HP:0001730) | 1.55414662 |
155 | Embryonal renal neoplasm (HP:0011794) | 1.55062065 |
156 | Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003) | 1.54695614 |
157 | Absent epiphyses (HP:0010577) | 1.54695614 |
158 | Fasciculations (HP:0002380) | 1.53978062 |
159 | Upper motor neuron abnormality (HP:0002127) | 1.52629421 |
160 | Abnormality of the ileum (HP:0001549) | 1.51972350 |
Rank | Gene Set | Z-score |
---|---|---|
1 | BUB1 | 3.99780135 |
2 | NEK1 | 3.81206892 |
3 | EIF2AK1 | 3.27347381 |
4 | CDC7 | 3.24090980 |
5 | WEE1 | 3.20613502 |
6 | PKN2 | 3.10304395 |
7 | SMG1 | 2.81925609 |
8 | SCYL2 | 2.80966076 |
9 | VRK2 | 2.62972188 |
10 | TESK2 | 2.44528010 |
11 | EIF2AK3 | 2.35080548 |
12 | TESK1 | 2.17397497 |
13 | RPS6KB2 | 2.05702478 |
14 | PAK4 | 1.95736779 |
15 | NEK2 | 1.93314316 |
16 | LATS2 | 1.79016411 |
17 | TSSK6 | 1.73874092 |
18 | MAP3K9 | 1.62071627 |
19 | BRSK1 | 1.61923408 |
20 | EPHA2 | 1.59704291 |
21 | LIMK1 | 1.56917537 |
22 | ALK | 1.50941164 |
23 | TRIB3 | 1.49980514 |
24 | MAP3K8 | 1.48964304 |
25 | RPS6KA4 | 1.43723153 |
26 | TTK | 1.42600620 |
27 | KSR2 | 1.40254049 |
28 | EEF2K | 1.39743401 |
29 | PLK1 | 1.39287735 |
30 | PLK3 | 1.37931973 |
31 | FLT3 | 1.37167292 |
32 | ICK | 1.33357032 |
33 | CDK19 | 1.31119228 |
34 | BRSK2 | 1.30383167 |
35 | PASK | 1.28365500 |
36 | TRIM28 | 1.28193010 |
37 | CDK7 | 1.25302748 |
38 | BCR | 1.22822828 |
39 | TAF1 | 1.22304535 |
40 | MINK1 | 1.20747809 |
41 | ARAF | 1.19556728 |
42 | KSR1 | 1.19431098 |
43 | BCKDK | 1.16498140 |
44 | PRPF4B | 1.14480936 |
45 | AURKA | 1.12105198 |
46 | IRAK3 | 1.09959953 |
47 | NTRK1 | 1.08318332 |
48 | CDK12 | 1.07814518 |
49 | BMX | 1.06850252 |
50 | MAP3K11 | 1.06048332 |
51 | LRRK2 | 1.04662713 |
52 | AURKB | 1.02867697 |
53 | ATR | 1.02347792 |
54 | ERBB4 | 1.02140465 |
55 | FGFR1 | 1.02132481 |
56 | STK16 | 0.99860344 |
57 | CSNK1G3 | 0.99054970 |
58 | PAK6 | 0.90042976 |
59 | KDR | 0.88804561 |
60 | NME2 | 0.87758158 |
61 | TAOK2 | 0.87255120 |
62 | CDK14 | 0.86887332 |
63 | LMTK2 | 0.86375857 |
64 | TTN | 0.85485037 |
65 | ILK | 0.85183472 |
66 | CSNK1A1L | 0.84431830 |
67 | ACVR1B | 0.84240485 |
68 | CDK4 | 0.82072125 |
69 | DAPK1 | 0.81751336 |
70 | CHEK1 | 0.79341138 |
71 | PAK2 | 0.78841616 |
72 | MAP3K10 | 0.78387672 |
73 | MAPKAPK3 | 0.77571691 |
74 | CDK18 | 0.75636782 |
75 | CDK15 | 0.74624700 |
76 | PLK4 | 0.74261597 |
77 | PLK2 | 0.70599506 |
78 | STK10 | 0.69657525 |
79 | * PAK1 | 0.69551226 |
80 | CSNK1G2 | 0.68390192 |
81 | CSNK1G1 | 0.67710110 |
82 | CDK11A | 0.67708027 |
83 | FGFR4 | 0.67168582 |
84 | CAMKK1 | 0.67080846 |
85 | CHEK2 | 0.65557113 |
86 | MKNK1 | 0.65270145 |
87 | BRAF | 0.63720098 |
88 | CDK6 | 0.63705218 |
89 | VRK1 | 0.63446030 |
90 | AKT2 | 0.62197163 |
91 | DAPK3 | 0.61734281 |
92 | CDK2 | 0.61189090 |
93 | PTK2 | 0.61033519 |
94 | RIPK1 | 0.60785262 |
95 | SIK3 | 0.59028843 |
96 | MET | 0.58524946 |
97 | MAP2K7 | 0.57789603 |
98 | PBK | 0.57338118 |
99 | ERN1 | 0.57217926 |
100 | PRKD3 | 0.56755111 |
101 | MOS | 0.56248859 |
102 | PDK2 | 0.55907548 |
103 | RAF1 | 0.55803749 |
104 | CAMKK2 | 0.53236469 |
105 | CDK8 | 0.52426756 |
106 | STK4 | 0.50826954 |
107 | MAP3K5 | 0.49440723 |
108 | STK38L | 0.48238887 |
109 | PIM2 | 0.47589347 |
110 | MTOR | 0.47539223 |
111 | PNCK | 0.46147681 |
112 | PDGFRA | 0.44948872 |
113 | DYRK2 | 0.43271934 |
114 | CSNK1E | 0.43071698 |
115 | ABL2 | 0.42992104 |
116 | DDR2 | 0.42846775 |
117 | MAP3K12 | 0.42360411 |
118 | MST1R | 0.42102215 |
119 | SRPK1 | 0.41104523 |
120 | TGFBR1 | 0.39972439 |
121 | ATM | 0.39838403 |
122 | UHMK1 | 0.39720657 |
123 | CDK1 | 0.39580925 |
124 | CSNK2A2 | 0.38900748 |
125 | PRKCI | 0.34781229 |
126 | NME1 | 0.34768076 |
127 | MAP2K1 | 0.33207228 |
128 | TLK1 | 0.32216717 |
Rank | Gene Set | Z-score |
---|---|---|
1 | DNA replication_Homo sapiens_hsa03030 | 4.29632657 |
2 | Mismatch repair_Homo sapiens_hsa03430 | 3.55388482 |
3 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 3.10746467 |
4 | Proteasome_Homo sapiens_hsa03050 | 3.00734066 |
5 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.94657400 |
6 | RNA transport_Homo sapiens_hsa03013 | 2.93072745 |
7 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.49904921 |
8 | Cell cycle_Homo sapiens_hsa04110 | 2.42081832 |
9 | Spliceosome_Homo sapiens_hsa03040 | 2.41152084 |
10 | * Biosynthesis of amino acids_Homo sapiens_hsa01230 | 2.28265933 |
11 | Ribosome_Homo sapiens_hsa03010 | 2.17266674 |
12 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.01990145 |
13 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.96445168 |
14 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.92227435 |
15 | Base excision repair_Homo sapiens_hsa03410 | 1.90984004 |
16 | * Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 1.89848579 |
17 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.82883628 |
18 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.60707901 |
19 | * Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 1.57583230 |
20 | * Carbon metabolism_Homo sapiens_hsa01200 | 1.56269912 |
21 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 1.54097679 |
22 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.50867324 |
23 | RNA polymerase_Homo sapiens_hsa03020 | 1.50391969 |
24 | Oocyte meiosis_Homo sapiens_hsa04114 | 1.49174251 |
25 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 1.44365381 |
26 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 1.43740629 |
27 | Homologous recombination_Homo sapiens_hsa03440 | 1.43572095 |
28 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.42645302 |
29 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 1.41887267 |
30 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.39529277 |
31 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.38175757 |
32 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 1.28884271 |
33 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.24703684 |
34 | Sulfur relay system_Homo sapiens_hsa04122 | 1.23877947 |
35 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 1.23805268 |
36 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.23236669 |
37 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.23088294 |
38 | RNA degradation_Homo sapiens_hsa03018 | 1.19356985 |
39 | Bladder cancer_Homo sapiens_hsa05219 | 1.19123554 |
40 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.15921735 |
41 | mTOR signaling pathway_Homo sapiens_hsa04150 | 1.12979337 |
42 | Galactose metabolism_Homo sapiens_hsa00052 | 1.12421762 |
43 | Thyroid cancer_Homo sapiens_hsa05216 | 1.04843897 |
44 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 1.04627486 |
45 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 1.00224167 |
46 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.99567530 |
47 | Glioma_Homo sapiens_hsa05214 | 0.97311201 |
48 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.96189790 |
49 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.90940541 |
50 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.90846546 |
51 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.89582269 |
52 | * Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.89310531 |
53 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.83659010 |
54 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.83303074 |
55 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.82155544 |
56 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.82148678 |
57 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.81377864 |
58 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.81101590 |
59 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.80231639 |
60 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.74739632 |
61 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.73815954 |
62 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.72231704 |
63 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.71385306 |
64 | Melanoma_Homo sapiens_hsa05218 | 0.70435580 |
65 | Purine metabolism_Homo sapiens_hsa00230 | 0.69847045 |
66 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.69620879 |
67 | Shigellosis_Homo sapiens_hsa05131 | 0.69080423 |
68 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.68943979 |
69 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.68010879 |
70 | Alcoholism_Homo sapiens_hsa05034 | 0.67231628 |
71 | Gap junction_Homo sapiens_hsa04540 | 0.65808164 |
72 | HTLV-I infection_Homo sapiens_hsa05166 | 0.65346026 |
73 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.65215353 |
74 | Colorectal cancer_Homo sapiens_hsa05210 | 0.64939315 |
75 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.62249835 |
76 | Legionellosis_Homo sapiens_hsa05134 | 0.62050467 |
77 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.60434526 |
78 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.60390527 |
79 | Phototransduction_Homo sapiens_hsa04744 | 0.59706952 |
80 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.59537945 |
81 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.58976627 |
82 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.56544149 |
83 | Protein export_Homo sapiens_hsa03060 | 0.55506807 |
84 | Long-term potentiation_Homo sapiens_hsa04720 | 0.52541656 |
85 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.51847109 |
86 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.51840074 |
87 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.49485024 |
88 | Phagosome_Homo sapiens_hsa04145 | 0.47110192 |
89 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.45967298 |
90 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.44617906 |
91 | Prion diseases_Homo sapiens_hsa05020 | 0.44566072 |
92 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.44382590 |
93 | Endometrial cancer_Homo sapiens_hsa05213 | 0.43894901 |
94 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.42423636 |
95 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.42163943 |
96 | Basal transcription factors_Homo sapiens_hsa03022 | 0.38916044 |
97 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.38674556 |
98 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.38273594 |
99 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.37842014 |
100 | Adherens junction_Homo sapiens_hsa04520 | 0.37629761 |
101 | Apoptosis_Homo sapiens_hsa04210 | 0.37045478 |
102 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.36272021 |
103 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.34919860 |
104 | * Metabolic pathways_Homo sapiens_hsa01100 | 0.34671559 |
105 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.34479601 |
106 | Parkinsons disease_Homo sapiens_hsa05012 | 0.32813379 |
107 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.32804868 |
108 | Lysine degradation_Homo sapiens_hsa00310 | 0.31403940 |
109 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.31297532 |
110 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.30837135 |
111 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.30708296 |
112 | Pathways in cancer_Homo sapiens_hsa05200 | 0.30006339 |
113 | Tight junction_Homo sapiens_hsa04530 | 0.29609109 |
114 | Huntingtons disease_Homo sapiens_hsa05016 | 0.28858929 |
115 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.28835098 |
116 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.28702808 |
117 | Focal adhesion_Homo sapiens_hsa04510 | 0.28622883 |
118 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.28372668 |
119 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.27985408 |
120 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.27077937 |
121 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.26801152 |
122 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.26447598 |
123 | Salmonella infection_Homo sapiens_hsa05132 | 0.24670139 |
124 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.24006303 |
125 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.23944876 |
126 | Alzheimers disease_Homo sapiens_hsa05010 | 0.23323956 |
127 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.22350788 |