PGAM1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene is a mutase that catalyzes the reversible reaction of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA) in the glycolytic pathway. Two transcript variants encoding different isoforms have been found for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA unwinding involved in DNA replication (GO:0006268)5.68684541
2establishment of viral latency (GO:0019043)5.03016740
3folic acid-containing compound biosynthetic process (GO:0009396)4.96065613
4IMP biosynthetic process (GO:0006188)4.90605320
5protein localization to kinetochore (GO:0034501)4.61249500
6nuclear pore organization (GO:0006999)4.55197718
7formation of translation preinitiation complex (GO:0001731)4.51796313
8L-serine metabolic process (GO:0006563)4.44356575
9DNA strand elongation involved in DNA replication (GO:0006271)4.43633204
10peptidyl-arginine omega-N-methylation (GO:0035247)4.40745037
11IMP metabolic process (GO:0046040)4.39783060
12regulation of translational termination (GO:0006449)4.36732722
13mitotic nuclear envelope disassembly (GO:0007077)4.34843382
14nucleobase biosynthetic process (GO:0046112)4.32033731
15DNA replication initiation (GO:0006270)4.23594092
16ribosome assembly (GO:0042255)4.19573238
17nuclear pore complex assembly (GO:0051292)4.17947910
18membrane disassembly (GO:0030397)4.13549929
19nuclear envelope disassembly (GO:0051081)4.13549929
20regulation of translational fidelity (GO:0006450)4.12862286
21DNA strand elongation (GO:0022616)4.12402869
22histone arginine methylation (GO:0034969)4.00483143
23purine nucleobase biosynthetic process (GO:0009113)3.91026624
24proline biosynthetic process (GO:0006561)3.86033700
25peptidyl-arginine N-methylation (GO:0035246)3.83123422
26peptidyl-arginine methylation (GO:0018216)3.83123422
27mitotic metaphase plate congression (GO:0007080)3.78241728
28heterochromatin organization (GO:0070828)3.72947297
29DNA replication-dependent nucleosome organization (GO:0034723)3.72854429
30DNA replication-dependent nucleosome assembly (GO:0006335)3.72854429
31telomere maintenance via semi-conservative replication (GO:0032201)3.71898127
32regulation of gene silencing by RNA (GO:0060966)3.68094457
33regulation of posttranscriptional gene silencing (GO:0060147)3.68094457
34regulation of gene silencing by miRNA (GO:0060964)3.68094457
35regulation of protein heterodimerization activity (GO:0043497)3.66436940
36cellular protein complex localization (GO:0034629)3.61906935
37protein localization to chromosome, centromeric region (GO:0071459)3.60456966
38mitotic G1 DNA damage checkpoint (GO:0031571)3.58773657
39pentose-phosphate shunt (GO:0006098)3.55971303
40mitotic sister chromatid segregation (GO:0000070)3.49697521
41ribosomal large subunit biogenesis (GO:0042273)3.46224030
42ribosome biogenesis (GO:0042254)3.46111712
43establishment of integrated proviral latency (GO:0075713)3.41602656
44mitotic nuclear envelope reassembly (GO:0007084)3.40994839
45nuclear envelope reassembly (GO:0031468)3.40994839
46tRNA aminoacylation for protein translation (GO:0006418)3.28740800
47DNA replication checkpoint (GO:0000076)3.27674235
48sister chromatid segregation (GO:0000819)3.26917257
49regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.22984515
50nucleobase-containing small molecule interconversion (GO:0015949)3.21484618
51nuclear envelope organization (GO:0006998)3.19375482
52negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.18673030
53negative regulation of ligase activity (GO:0051352)3.18673030
54telomere maintenance via recombination (GO:0000722)3.18181284
55amino acid activation (GO:0043038)3.16925431
56tRNA aminoacylation (GO:0043039)3.16925431
57pre-miRNA processing (GO:0031054)3.15345850
58de novo protein folding (GO:0006458)3.12824320
59DNA duplex unwinding (GO:0032508)3.12696755
60DNA geometric change (GO:0032392)3.11876777
61telomere maintenance via telomere lengthening (GO:0010833)3.10932023
62chaperone-mediated protein complex assembly (GO:0051131)3.10352258
63NADPH regeneration (GO:0006740)3.08692374
64mitotic recombination (GO:0006312)3.08430346
65protein complex localization (GO:0031503)3.05243101
66* glycolytic process (GO:0006096)3.04688028
67peptidyl-lysine dimethylation (GO:0018027)3.02964823
68pore complex assembly (GO:0046931)3.02525400
69de novo posttranslational protein folding (GO:0051084)3.02475781
70ribonucleoprotein complex biogenesis (GO:0022613)3.02057895
71metaphase plate congression (GO:0051310)3.01796746
72maintenance of protein localization in endoplasmic reticulum (GO:0035437)3.00548030
73regulation of centrosome cycle (GO:0046605)3.00083312
74mitochondrial fragmentation involved in apoptotic process (GO:0043653)2.97982967
75cell cycle G1/S phase transition (GO:0044843)2.97773536
76G1/S transition of mitotic cell cycle (GO:0000082)2.97773536
77negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.97739011
78protein retention in ER lumen (GO:0006621)2.97050002
79COPI coating of Golgi vesicle (GO:0048205)2.96832729
80Golgi transport vesicle coating (GO:0048200)2.96832729
81mitotic G1/S transition checkpoint (GO:0044819)2.96811195
82regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)2.95695903
83snRNA processing (GO:0016180)2.94506522
84mitochondrial fusion (GO:0008053)2.94254406
85serine family amino acid biosynthetic process (GO:0009070)2.93938734
86glucose 6-phosphate metabolic process (GO:0051156)2.92877687
87translational initiation (GO:0006413)2.91451395
88regulation of spindle organization (GO:0090224)2.89137687
89anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.88611326
90retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)2.87794093
91deoxyribonucleotide biosynthetic process (GO:0009263)2.86551029
92maturation of SSU-rRNA (GO:0030490)2.86076224
93nucleotide-excision repair, DNA gap filling (GO:0006297)2.85091938
94spliceosomal snRNP assembly (GO:0000387)2.84031210
95negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.83517601
96regulation of mammary gland epithelial cell proliferation (GO:0033599)2.83348781
97regulation of mitochondrial translation (GO:0070129)2.82476761
98establishment of chromosome localization (GO:0051303)2.81759719
99postreplication repair (GO:0006301)2.79754466
100G1 DNA damage checkpoint (GO:0044783)2.78996610
101positive regulation of chromosome segregation (GO:0051984)2.77597591
102mitotic chromosome condensation (GO:0007076)2.76474738
103histone-serine phosphorylation (GO:0035404)2.76445712
1044-hydroxyproline metabolic process (GO:0019471)2.75550462
105attachment of spindle microtubules to kinetochore (GO:0008608)2.75289954
106tricarboxylic acid cycle (GO:0006099)2.75040452
107regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.74573866
108protein maturation by protein folding (GO:0022417)2.72647800
109translational elongation (GO:0006414)2.72533462
110spliceosomal tri-snRNP complex assembly (GO:0000244)2.72525440
111positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.71699989
112negative regulation of mitotic sister chromatid segregation (GO:0033048)2.69490809
113negative regulation of mitotic sister chromatid separation (GO:2000816)2.69490809
114negative regulation of sister chromatid segregation (GO:0033046)2.69490809
115negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.69490809
116negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.69490809
117base-excision repair (GO:0006284)2.69225176
118double-strand break repair via nonhomologous end joining (GO:0006303)2.68744197
119non-recombinational repair (GO:0000726)2.68744197
120glucocorticoid receptor signaling pathway (GO:0042921)2.68727800
121snRNA metabolic process (GO:0016073)2.67707952
122protein export from nucleus (GO:0006611)2.67409035
123regulation of ubiquitin-protein transferase activity (GO:0051438)2.65606132
124spindle checkpoint (GO:0031577)2.65478258
125regulation of mitotic spindle organization (GO:0060236)2.65365768
126proteasome assembly (GO:0043248)2.64101541
127DNA damage response, detection of DNA damage (GO:0042769)2.63971658
128pteridine-containing compound biosynthetic process (GO:0042559)2.63294225
129regulation of centriole replication (GO:0046599)2.63014526
130regulation of translational elongation (GO:0006448)2.62763600
131translational termination (GO:0006415)2.62339546
132regulation of chromosome segregation (GO:0051983)2.62241599
133negative regulation of chromosome segregation (GO:0051985)2.62099385
134mitotic spindle checkpoint (GO:0071174)2.61722562
135pseudouridine synthesis (GO:0001522)2.61439689
136mitotic spindle assembly checkpoint (GO:0007094)2.60170406

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.84935503
2MYC_18555785_ChIP-Seq_MESCs_Mouse4.55662030
3EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse4.46152228
4FOXM1_23109430_ChIP-Seq_U2OS_Human4.16723043
5MYC_19079543_ChIP-ChIP_MESCs_Mouse3.25433665
6E2F4_17652178_ChIP-ChIP_JURKAT_Human3.12563073
7* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.83996167
8* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.81609766
9EGR1_19374776_ChIP-ChIP_THP-1_Human2.72185689
10FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.55382773
11XRN2_22483619_ChIP-Seq_HELA_Human2.46407338
12NELFA_20434984_ChIP-Seq_ESCs_Mouse2.43387490
13ETS1_20019798_ChIP-Seq_JURKAT_Human2.43089747
14CREB1_15753290_ChIP-ChIP_HEK293T_Human2.38328982
15* POU5F1_18700969_ChIP-ChIP_MESCs_Mouse2.30777724
16EST1_17652178_ChIP-ChIP_JURKAT_Human2.29449740
17HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.20817635
18AR_21909140_ChIP-Seq_LNCAP_Human2.19268296
19KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.17338713
20JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.16803349
21E2F1_18555785_ChIP-Seq_MESCs_Mouse2.06217366
22GABP_17652178_ChIP-ChIP_JURKAT_Human1.98060712
23ZFX_18555785_ChIP-Seq_MESCs_Mouse1.93906211
24E2F1_21310950_ChIP-Seq_MCF-7_Human1.85937950
25* MYCN_18555785_ChIP-Seq_MESCs_Mouse1.85245394
26THAP11_20581084_ChIP-Seq_MESCs_Mouse1.85049215
27* DCP1A_22483619_ChIP-Seq_HELA_Human1.84520444
28POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.79291724
29ESR1_15608294_ChIP-ChIP_MCF-7_Human1.78347939
30ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.77285232
31MYC_22102868_ChIP-Seq_BL_Human1.75799733
32* KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.74295051
33MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.72076763
34NANOG_18555785_ChIP-Seq_MESCs_Mouse1.71912971
35CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.71625677
36* GABP_19822575_ChIP-Seq_HepG2_Human1.70157741
37NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.68569827
38TTF2_22483619_ChIP-Seq_HELA_Human1.68229573
39NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.59680727
40MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.56205442
41STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.55338102
42CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.52706464
43TFEB_21752829_ChIP-Seq_HELA_Human1.52557697
44NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.52491052
45* PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.52064075
46VDR_23849224_ChIP-Seq_CD4+_Human1.50405295
47* HIF1A_21447827_ChIP-Seq_MCF-7_Human1.49819565
48KLF4_18555785_ChIP-Seq_MESCs_Mouse1.48957929
49ZNF263_19887448_ChIP-Seq_K562_Human1.48281961
50* KDM5A_27292631_Chip-Seq_BREAST_Human1.46922037
51CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.46007394
52PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.43937367
53* DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.42461308
54TP63_17297297_ChIP-ChIP_HaCaT_Human1.41918483
55FOXP3_21729870_ChIP-Seq_TREG_Human1.40448838
56RBPJ_22232070_ChIP-Seq_NCS_Mouse1.38905408
57YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.38265614
58STAT3_1855785_ChIP-Seq_MESCs_Mouse1.38233038
59ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.38192898
60TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.38069005
61KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.35810669
62CLOCK_20551151_ChIP-Seq_293T_Human1.34018819
63* ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.29204796
64* ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.27833775
65TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.26988637
66* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.25955742
67SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.23107719
68ATF3_27146783_Chip-Seq_COLON_Human1.22600149
69PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.22484288
70POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.22316319
71SREBP1_19666523_ChIP-Seq_LIVER_Mouse1.21712256
72DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.20855493
73* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.20438200
74ZFP281_18757296_ChIP-ChIP_E14_Mouse1.20134711
75HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.19901391
76CIITA_25753668_ChIP-Seq_RAJI_Human1.19172251
77YY1_21170310_ChIP-Seq_MESCs_Mouse1.16566874
78TCF3_18692474_ChIP-Seq_MEFs_Mouse1.14640759
79VDR_21846776_ChIP-Seq_THP-1_Human1.14378193
80PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.14211258
81HOXB4_20404135_ChIP-ChIP_EML_Mouse1.14020396
82SRY_22984422_ChIP-ChIP_TESTIS_Rat1.13734422
83TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.13199641
84KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.12962179
85OCT4_18692474_ChIP-Seq_MEFs_Mouse1.12368433
86CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.10108978
87PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.09144700
88ERG_20887958_ChIP-Seq_HPC-7_Mouse1.08797978
89ELK1_19687146_ChIP-ChIP_HELA_Human1.07750778
90* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.07540919
91SOX2_18555785_ChIP-Seq_MESCs_Mouse1.06216160
92HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.05842042
93* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.05818578
94TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.04892813
95* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.03600992
96TRIM28_19339689_ChIP-ChIP_MESCs_Mouse1.03542661
97SOX17_20123909_ChIP-Seq_XEN_Mouse1.02692253
98TCFCP2L1_18555785_ChIP-Seq_MESCs_Mouse1.02502515
99SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.01434178
100* NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.01140476
101NANOG_21062744_ChIP-ChIP_HESCs_Human1.00304490
102* SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.99448398
103NACC1_18358816_ChIP-ChIP_MESCs_Mouse0.98865992
104TBX5_21415370_ChIP-Seq_HL-1_Mouse0.98665718
105ELK3_25401928_ChIP-Seq_HUVEC_Human0.97196675
106* ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.96406668
107SRF_21415370_ChIP-Seq_HL-1_Mouse0.96025583
108FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse0.94088626
109SOX2_18692474_ChIP-Seq_MEFs_Mouse0.93684104
110NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.92646547
111ELF1_17652178_ChIP-ChIP_JURKAT_Human0.92023940
112ELK1_22589737_ChIP-Seq_MCF10A_Human0.91776631
113CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.91370741
114* CHD1_26751641_Chip-Seq_LNCaP_Human0.90570114
115CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.90473107
116BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.90085864
117EOMES_20176728_ChIP-ChIP_TSCs_Mouse0.89879204
118SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.89623587
119RARG_19884340_ChIP-ChIP_MEFs_Mouse0.89576135

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010352_gastrointestinal_tract_polyps3.94128192
2MP0004957_abnormal_blastocyst_morpholog3.69416083
3MP0003705_abnormal_hypodermis_morpholog3.69202899
4MP0003693_abnormal_embryo_hatching3.64498387
5MP0003123_paternal_imprinting3.57484476
6MP0003111_abnormal_nucleus_morphology3.43715586
7MP0010030_abnormal_orbit_morphology3.13839403
8MP0010094_abnormal_chromosome_stability3.05623310
9MP0003077_abnormal_cell_cycle3.01171814
10MP0003941_abnormal_skin_development2.79402311
11MP0001730_embryonic_growth_arrest2.70395548
12MP0008932_abnormal_embryonic_tissue2.50001921
13MP0004233_abnormal_muscle_weight2.47914909
14MP0010307_abnormal_tumor_latency2.38852687
15MP0000537_abnormal_urethra_morphology2.28951249
16MP0000350_abnormal_cell_proliferation2.18369607
17MP0005076_abnormal_cell_differentiation2.11984111
18MP0004272_abnormal_basement_membrane2.10114642
19MP0003283_abnormal_digestive_organ2.01774607
20MP0001697_abnormal_embryo_size1.96010514
21MP0010234_abnormal_vibrissa_follicle1.91329997
22MP0004133_heterotaxia1.89211681
23MP0008260_abnormal_autophagy1.86536232
24MP0008007_abnormal_cellular_replicative1.86278842
25MP0004197_abnormal_fetal_growth/weight/1.86102635
26MP0002084_abnormal_developmental_patter1.80119163
27MP0001672_abnormal_embryogenesis/_devel1.77609421
28MP0005380_embryogenesis_phenotype1.77609421
29MP0002080_prenatal_lethality1.76348380
30MP0003984_embryonic_growth_retardation1.75329612
31MP0002088_abnormal_embryonic_growth/wei1.70812231
32MP0005501_abnormal_skin_physiology1.69645908
33MP0002796_impaired_skin_barrier1.69299119
34MP0000358_abnormal_cell_content/1.67565263
35MP0002085_abnormal_embryonic_tissue1.66433805
36MP0003121_genomic_imprinting1.63729654
37MP0008057_abnormal_DNA_replication1.60840687
38MP0003221_abnormal_cardiomyocyte_apopto1.57804142
39MP0003890_abnormal_embryonic-extraembry1.57466104
40MP0002877_abnormal_melanocyte_morpholog1.54912599
41MP0002086_abnormal_extraembryonic_tissu1.49440448
42MP0003172_abnormal_lysosome_physiology1.48137188
43MP0003566_abnormal_cell_adhesion1.46074247
44MP0009053_abnormal_anal_canal1.44358125
45MP0003119_abnormal_digestive_system1.42042702
46MP0002254_reproductive_system_inflammat1.40795326
47MP0003315_abnormal_perineum_morphology1.40224377
48MP0008058_abnormal_DNA_repair1.40066669
49MP0001299_abnormal_eye_distance/1.36107353
50MP0001293_anophthalmia1.34063058
51MP0001346_abnormal_lacrimal_gland1.33631393
52MP0005023_abnormal_wound_healing1.33604492
53MP0003567_abnormal_fetal_cardiomyocyte1.32282271
54MP0005623_abnormal_meninges_morphology1.30558627
55MP0003122_maternal_imprinting1.29557968
56MP0001529_abnormal_vocalization1.26876150
57MP0004858_abnormal_nervous_system1.26773300
58MP0002234_abnormal_pharynx_morphology1.25636406
59MP0002653_abnormal_ependyma_morphology1.25241713
60MP0000579_abnormal_nail_morphology1.22234211
61MP0003786_premature_aging1.20153223
62MP0004084_abnormal_cardiac_muscle1.15230552
63MP0008877_abnormal_DNA_methylation1.14860910
64MP0005394_taste/olfaction_phenotype1.13085000
65MP0005499_abnormal_olfactory_system1.13085000
66MP0005451_abnormal_body_composition1.12355507
67MP0009672_abnormal_birth_weight1.11449448
68MP0006072_abnormal_retinal_apoptosis1.11219939
69MP0000534_abnormal_ureter_morphology1.10937553
70MP0003942_abnormal_urinary_system1.09969689
71MP0000858_altered_metastatic_potential1.09869243
72MP0001348_abnormal_lacrimal_gland1.09739087
73MP0000313_abnormal_cell_death1.09659112
74MP0005384_cellular_phenotype1.09634407
75MP0003385_abnormal_body_wall1.04183951
76MP0000762_abnormal_tongue_morphology1.03039275
77MP0000750_abnormal_muscle_regeneration1.02366432
78MP0005248_abnormal_Harderian_gland1.02009859
79MP0003937_abnormal_limbs/digits/tail_de1.00970913
80MP0002269_muscular_atrophy1.00255689
81MP0001849_ear_inflammation0.96015641
82MP0005621_abnormal_cell_physiology0.96013033
83MP0003718_maternal_effect0.93048160
84MP0003115_abnormal_respiratory_system0.90362814
85MP0003186_abnormal_redox_activity0.90149878
86MP0002019_abnormal_tumor_incidence0.89868820
87MP0004859_abnormal_synaptic_plasticity0.89442550
88MP0002060_abnormal_skin_morphology0.89220697
89MP0009697_abnormal_copulation0.89071479
90MP0002111_abnormal_tail_morphology0.89049502
91MP0000428_abnormal_craniofacial_morphol0.88939309
92MP0001915_intracranial_hemorrhage0.88682953
93MP0002089_abnormal_postnatal_growth/wei0.86858715
94MP0000490_abnormal_crypts_of0.86312006
95MP0003303_peritoneal_inflammation0.84997802
96MP0001661_extended_life_span0.84710496
97MP0002090_abnormal_vision0.84333697
98MP0008770_decreased_survivor_rate0.83565229
99MP0003453_abnormal_keratinocyte_physiol0.83129819
100MP0005257_abnormal_intraocular_pressure0.82370406
101MP0002751_abnormal_autonomic_nervous0.81378027
102MP0003806_abnormal_nucleotide_metabolis0.80310634
103MP0000733_abnormal_muscle_development0.79580575
104MP0002092_abnormal_eye_morphology0.76383519
105MP0000751_myopathy0.75598704
106MP0003861_abnormal_nervous_system0.72137348
107MP0003329_amyloid_beta_deposits0.72123266
108MP0005266_abnormal_metabolism0.72034866
109MP0006035_abnormal_mitochondrial_morpho0.71512188
110MP0004808_abnormal_hematopoietic_stem0.70561418
111MP0001216_abnormal_epidermal_layer0.69001666
112MP0002233_abnormal_nose_morphology0.68468201
113MP0009703_decreased_birth_body0.67635129
114MP0001188_hyperpigmentation0.66904307
115MP0005391_vision/eye_phenotype0.66775388
116MP0005193_abnormal_anterior_eye0.66618957
117MP0001286_abnormal_eye_development0.66428114
118MP0000747_muscle_weakness0.65836864
119MP0000371_diluted_coat_color0.65154334
120MP0002697_abnormal_eye_size0.64777808
121MP0008438_abnormal_cutaneous_collagen0.64441991
122MP0003091_abnormal_cell_migration0.64393524
123MP0004185_abnormal_adipocyte_glucose0.64034577
124MP0001340_abnormal_eyelid_morphology0.63985407
125MP0000566_synostosis0.63675108
126MP0003448_altered_tumor_morphology0.61763368
127MP0002925_abnormal_cardiovascular_devel0.61206863
128MP0005197_abnormal_uvea_morphology0.60519007
129MP0002332_abnormal_exercise_endurance0.60347272
130MP0000266_abnormal_heart_morphology0.58600224
131MP0002282_abnormal_trachea_morphology0.58369957
132MP0001727_abnormal_embryo_implantation0.57958820
133MP0005551_abnormal_eye_electrophysiolog0.56706643
134MP0001324_abnormal_eye_pigmentation0.56380698

Predicted human phenotypes

RankGene SetZ-score
1Ependymoma (HP:0002888)4.07601528
2Cortical dysplasia (HP:0002539)3.84853861
3Selective tooth agenesis (HP:0001592)3.40125644
4Agnosia (HP:0010524)3.32140745
5Premature rupture of membranes (HP:0001788)3.30146010
6Adenoma sebaceum (HP:0009720)3.17140381
7Angiofibromas (HP:0010615)3.17140381
8Astrocytoma (HP:0009592)3.13274997
9Abnormality of the astrocytes (HP:0100707)3.13274997
10Degeneration of anterior horn cells (HP:0002398)3.01488895
11Abnormality of the anterior horn cell (HP:0006802)3.01488895
12Colon cancer (HP:0003003)2.99847796
13Congenital stationary night blindness (HP:0007642)2.95038910
14Birth length less than 3rd percentile (HP:0003561)2.82860299
15Hand muscle atrophy (HP:0009130)2.74575671
16Insomnia (HP:0100785)2.73911421
17Long palpebral fissure (HP:0000637)2.64221396
18Microvesicular hepatic steatosis (HP:0001414)2.63722301
19Upper limb muscle weakness (HP:0003484)2.63713573
20Abnormal number of incisors (HP:0011064)2.57800107
21Medulloblastoma (HP:0002885)2.50889611
22Trismus (HP:0000211)2.48045750
23Chromosomal breakage induced by crosslinking agents (HP:0003221)2.47573422
24Abnormality of the labia minora (HP:0012880)2.44690205
25Deviation of the thumb (HP:0009603)2.43263389
26Basal cell carcinoma (HP:0002671)2.40040599
27Abnormality of cells of the erythroid lineage (HP:0012130)2.35498003
28Exercise-induced muscle cramps (HP:0003710)2.35175408
29Upper limb amyotrophy (HP:0009129)2.33569237
30Distal upper limb amyotrophy (HP:0007149)2.33569237
31Progressive external ophthalmoplegia (HP:0000590)2.32278691
32Increased serum pyruvate (HP:0003542)2.31035896
33Abnormality of glycolysis (HP:0004366)2.31035896
34Severe visual impairment (HP:0001141)2.30459799
35Proximal placement of thumb (HP:0009623)2.29961894
36Genu recurvatum (HP:0002816)2.29815534
37Abnormality of the umbilical cord (HP:0010881)2.29668155
38Glioma (HP:0009733)2.28054764
39Spastic diplegia (HP:0001264)2.25816238
40Missing ribs (HP:0000921)2.25235487
41Cutaneous melanoma (HP:0012056)2.24090938
42Stenosis of the external auditory canal (HP:0000402)2.23535109
43Atrophy/Degeneration involving motor neurons (HP:0007373)2.22058711
44Increased nuchal translucency (HP:0010880)2.21826510
45Abnormality of abdominal situs (HP:0011620)2.20778735
46Abdominal situs inversus (HP:0003363)2.20778735
47Neoplasm of the pancreas (HP:0002894)2.20460633
48Renal duplication (HP:0000075)2.18717891
49Overriding aorta (HP:0002623)2.18301267
50Pointed chin (HP:0000307)2.16000571
51Chromsome breakage (HP:0040012)2.15899624
52Pelvic girdle muscle weakness (HP:0003749)2.14269770
53Shoulder girdle muscle weakness (HP:0003547)2.13979230
54Ovarian neoplasm (HP:0100615)2.13643266
55Oral leukoplakia (HP:0002745)2.12162880
56Cerebral hypomyelination (HP:0006808)2.10820872
57Multiple enchondromatosis (HP:0005701)2.10637673
58Hyperacusis (HP:0010780)2.08845560
59Deep palmar crease (HP:0006191)2.08793894
60Neuroblastic tumors (HP:0004376)2.08363018
61Peripheral primitive neuroectodermal neoplasm (HP:0030067)2.08363018
62Neuroblastoma (HP:0003006)2.08363018
63Primitive neuroectodermal tumor (HP:0030065)2.08363018
64Reticulocytopenia (HP:0001896)2.08162699
65Increased density of long bones (HP:0006392)2.08159515
66Protrusio acetabuli (HP:0003179)2.08110196
67Aplasia/Hypoplasia of the sacrum (HP:0008517)2.06590230
68Generalized hypotonia (HP:0001290)2.06306906
69Ragged-red muscle fibers (HP:0003200)2.05223412
70Ankle contracture (HP:0006466)2.04530566
71Horseshoe kidney (HP:0000085)2.03961109
72Metaphyseal cupping (HP:0003021)2.03926364
73Breast hypoplasia (HP:0003187)2.03723657
74Postnatal microcephaly (HP:0005484)2.03203006
75Aplasia/hypoplasia of the humerus (HP:0006507)2.02639898
76Rhabdomyolysis (HP:0003201)2.02258707
77Progressive muscle weakness (HP:0003323)1.99563475
78Slender long bone (HP:0003100)1.99535901
79Abnormal gallbladder physiology (HP:0012438)1.99316312
80Cholecystitis (HP:0001082)1.99316312
81Fibroma (HP:0010614)1.98881477
82Absent thumb (HP:0009777)1.98200349
83Rhabdomyosarcoma (HP:0002859)1.98174464
84Ankyloglossia (HP:0010296)1.98038790
85Facial cleft (HP:0002006)1.95929936
86Intestinal polyp (HP:0005266)1.94756407
87Hypoplasia of the capital femoral epiphysis (HP:0003090)1.94520404
88Broad distal phalanx of finger (HP:0009836)1.93870929
89Intestinal polyposis (HP:0200008)1.93209050
90Abnormality of the lower motor neuron (HP:0002366)1.93086358
91Rough bone trabeculation (HP:0100670)1.92970898
92Vertebral compression fractures (HP:0002953)1.92748572
93Diminished motivation (HP:0000745)1.91546423
94Abnormal lung lobation (HP:0002101)1.91265290
95Freckling (HP:0001480)1.91018089
96Abnormality of the motor neurons (HP:0002450)1.90712111
97Abnormal neuron morphology (HP:0012757)1.90712111
98Atresia of the external auditory canal (HP:0000413)1.89893421
99Trigonocephaly (HP:0000243)1.89410369
100Short humerus (HP:0005792)1.87918795
101Bowel diverticulosis (HP:0005222)1.87908067
102Fibrous tissue neoplasm (HP:0012316)1.87655504
103Spinal cord compression (HP:0002176)1.86908587
104Annular pancreas (HP:0001734)1.85071837
105Abnormality of the calcaneus (HP:0008364)1.84986574
106Biliary tract neoplasm (HP:0100574)1.84210487
107Glossoptosis (HP:0000162)1.83016419
108Abnormal umbilical cord blood vessels (HP:0011403)1.82712383
109Single umbilical artery (HP:0001195)1.82712383
110Abnormality of the fetal cardiovascular system (HP:0010948)1.82712383
111Insidious onset (HP:0003587)1.82437614
112Termporal pattern (HP:0011008)1.82437614
113Cholelithiasis (HP:0001081)1.81498722
114Apathy (HP:0000741)1.79901984
115Achilles tendon contracture (HP:0001771)1.78525610
116Abnormalities of placenta or umbilical cord (HP:0001194)1.78516066
117Cervical subluxation (HP:0003308)1.77115110
118Abnormality of oral frenula (HP:0000190)1.76781776
119Gout (HP:0001997)1.75935832
120Microretrognathia (HP:0000308)1.75655477
121Neoplasm of the colon (HP:0100273)1.75318069
122Spinal muscular atrophy (HP:0007269)1.75224415
123Neoplasm of the adrenal gland (HP:0100631)1.75076431
124Vertebral hypoplasia (HP:0008417)1.71783695
125Aplasia/Hypoplasia of the vertebrae (HP:0008515)1.71783695
126Abnormality of the hip-girdle musculature (HP:0001445)1.71753786
127Abnormality of the musculature of the pelvis (HP:0001469)1.71753786
128Microglossia (HP:0000171)1.71513424
129Abnormality of macular pigmentation (HP:0008002)1.71315719
130Secondary amenorrhea (HP:0000869)1.70114457
131Impaired pain sensation (HP:0007328)1.69362548
132Abnormality of pain sensation (HP:0010832)1.69362548
133High anterior hairline (HP:0009890)1.67194047
134Choanal stenosis (HP:0000452)1.67186523
135Meckel diverticulum (HP:0002245)1.67030085
136Duplication of thumb phalanx (HP:0009942)1.66970091
137Prominent metopic ridge (HP:0005487)1.66655310
138Back pain (HP:0003418)1.65781869
139Absent radius (HP:0003974)1.63897012
140Nephroblastoma (Wilms tumor) (HP:0002667)1.63805939
141Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.62047069
142Abnormal trabecular bone morphology (HP:0100671)1.61268792
143Abnormal gallbladder morphology (HP:0012437)1.60315858
144Lower limb amyotrophy (HP:0007210)1.59925463
145Entropion (HP:0000621)1.59245461
146Hypoplastic pelvis (HP:0008839)1.59057002
147Hammertoe (HP:0001765)1.58947699
148Aplasia involving forearm bones (HP:0009822)1.58807508
149Absent forearm bone (HP:0003953)1.58807508
150Squamous cell carcinoma (HP:0002860)1.58270725
151Pterygium (HP:0001059)1.57643182
152Reduced antithrombin III activity (HP:0001976)1.57188245
153Elfin facies (HP:0004428)1.56409448
154Progressive hearing impairment (HP:0001730)1.55414662
155Embryonal renal neoplasm (HP:0011794)1.55062065
156Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.54695614
157Absent epiphyses (HP:0010577)1.54695614
158Fasciculations (HP:0002380)1.53978062
159Upper motor neuron abnormality (HP:0002127)1.52629421
160Abnormality of the ileum (HP:0001549)1.51972350

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB13.99780135
2NEK13.81206892
3EIF2AK13.27347381
4CDC73.24090980
5WEE13.20613502
6PKN23.10304395
7SMG12.81925609
8SCYL22.80966076
9VRK22.62972188
10TESK22.44528010
11EIF2AK32.35080548
12TESK12.17397497
13RPS6KB22.05702478
14PAK41.95736779
15NEK21.93314316
16LATS21.79016411
17TSSK61.73874092
18MAP3K91.62071627
19BRSK11.61923408
20EPHA21.59704291
21LIMK11.56917537
22ALK1.50941164
23TRIB31.49980514
24MAP3K81.48964304
25RPS6KA41.43723153
26TTK1.42600620
27KSR21.40254049
28EEF2K1.39743401
29PLK11.39287735
30PLK31.37931973
31FLT31.37167292
32ICK1.33357032
33CDK191.31119228
34BRSK21.30383167
35PASK1.28365500
36TRIM281.28193010
37CDK71.25302748
38BCR1.22822828
39TAF11.22304535
40MINK11.20747809
41ARAF1.19556728
42KSR11.19431098
43BCKDK1.16498140
44PRPF4B1.14480936
45AURKA1.12105198
46IRAK31.09959953
47NTRK11.08318332
48CDK121.07814518
49BMX1.06850252
50MAP3K111.06048332
51LRRK21.04662713
52AURKB1.02867697
53ATR1.02347792
54ERBB41.02140465
55FGFR11.02132481
56STK160.99860344
57CSNK1G30.99054970
58PAK60.90042976
59KDR0.88804561
60NME20.87758158
61TAOK20.87255120
62CDK140.86887332
63LMTK20.86375857
64TTN0.85485037
65ILK0.85183472
66CSNK1A1L0.84431830
67ACVR1B0.84240485
68CDK40.82072125
69DAPK10.81751336
70CHEK10.79341138
71PAK20.78841616
72MAP3K100.78387672
73MAPKAPK30.77571691
74CDK180.75636782
75CDK150.74624700
76PLK40.74261597
77PLK20.70599506
78STK100.69657525
79* PAK10.69551226
80CSNK1G20.68390192
81CSNK1G10.67710110
82CDK11A0.67708027
83FGFR40.67168582
84CAMKK10.67080846
85CHEK20.65557113
86MKNK10.65270145
87BRAF0.63720098
88CDK60.63705218
89VRK10.63446030
90AKT20.62197163
91DAPK30.61734281
92CDK20.61189090
93PTK20.61033519
94RIPK10.60785262
95SIK30.59028843
96MET0.58524946
97MAP2K70.57789603
98PBK0.57338118
99ERN10.57217926
100PRKD30.56755111
101MOS0.56248859
102PDK20.55907548
103RAF10.55803749
104CAMKK20.53236469
105CDK80.52426756
106STK40.50826954
107MAP3K50.49440723
108STK38L0.48238887
109PIM20.47589347
110MTOR0.47539223
111PNCK0.46147681
112PDGFRA0.44948872
113DYRK20.43271934
114CSNK1E0.43071698
115ABL20.42992104
116DDR20.42846775
117MAP3K120.42360411
118MST1R0.42102215
119SRPK10.41104523
120TGFBR10.39972439
121ATM0.39838403
122UHMK10.39720657
123CDK10.39580925
124CSNK2A20.38900748
125PRKCI0.34781229
126NME10.34768076
127MAP2K10.33207228
128TLK10.32216717

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.29632657
2Mismatch repair_Homo sapiens_hsa034303.55388482
3Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009703.10746467
4Proteasome_Homo sapiens_hsa030503.00734066
5Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.94657400
6RNA transport_Homo sapiens_hsa030132.93072745
7One carbon pool by folate_Homo sapiens_hsa006702.49904921
8Cell cycle_Homo sapiens_hsa041102.42081832
9Spliceosome_Homo sapiens_hsa030402.41152084
10* Biosynthesis of amino acids_Homo sapiens_hsa012302.28265933
11Ribosome_Homo sapiens_hsa030102.17266674
12Nucleotide excision repair_Homo sapiens_hsa034202.01990145
132-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.96445168
14Vitamin B6 metabolism_Homo sapiens_hsa007501.92227435
15Base excision repair_Homo sapiens_hsa034101.90984004
16* Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.89848579
17Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.82883628
18Steroid biosynthesis_Homo sapiens_hsa001001.60707901
19* Central carbon metabolism in cancer_Homo sapiens_hsa052301.57583230
20* Carbon metabolism_Homo sapiens_hsa012001.56269912
21Fructose and mannose metabolism_Homo sapiens_hsa000511.54097679
22Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.50867324
23RNA polymerase_Homo sapiens_hsa030201.50391969
24Oocyte meiosis_Homo sapiens_hsa041141.49174251
25Pentose phosphate pathway_Homo sapiens_hsa000301.44365381
26HIF-1 signaling pathway_Homo sapiens_hsa040661.43740629
27Homologous recombination_Homo sapiens_hsa034401.43572095
28Fatty acid elongation_Homo sapiens_hsa000621.42645302
29Synaptic vesicle cycle_Homo sapiens_hsa047211.41887267
30Pyrimidine metabolism_Homo sapiens_hsa002401.39529277
31Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.38175757
32Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.28884271
33mRNA surveillance pathway_Homo sapiens_hsa030151.24703684
34Sulfur relay system_Homo sapiens_hsa041221.23877947
35Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.23805268
36p53 signaling pathway_Homo sapiens_hsa041151.23236669
37Folate biosynthesis_Homo sapiens_hsa007901.23088294
38RNA degradation_Homo sapiens_hsa030181.19356985
39Bladder cancer_Homo sapiens_hsa052191.19123554
40Cysteine and methionine metabolism_Homo sapiens_hsa002701.15921735
41mTOR signaling pathway_Homo sapiens_hsa041501.12979337
42Galactose metabolism_Homo sapiens_hsa000521.12421762
43Thyroid cancer_Homo sapiens_hsa052161.04843897
44Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.04627486
45Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.00224167
46Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.99567530
47Glioma_Homo sapiens_hsa052140.97311201
48Vibrio cholerae infection_Homo sapiens_hsa051100.96189790
49Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.90940541
50Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.90846546
51Viral carcinogenesis_Homo sapiens_hsa052030.89582269
52* Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.89310531
53Hippo signaling pathway_Homo sapiens_hsa043900.83659010
54Arginine and proline metabolism_Homo sapiens_hsa003300.83303074
55Cyanoamino acid metabolism_Homo sapiens_hsa004600.82155544
56Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.82148678
57Selenocompound metabolism_Homo sapiens_hsa004500.81377864
58Epstein-Barr virus infection_Homo sapiens_hsa051690.81101590
59Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.80231639
60MicroRNAs in cancer_Homo sapiens_hsa052060.74739632
61Chronic myeloid leukemia_Homo sapiens_hsa052200.73815954
62Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.72231704
63Proteoglycans in cancer_Homo sapiens_hsa052050.71385306
64Melanoma_Homo sapiens_hsa052180.70435580
65Purine metabolism_Homo sapiens_hsa002300.69847045
66Fanconi anemia pathway_Homo sapiens_hsa034600.69620879
67Shigellosis_Homo sapiens_hsa051310.69080423
68Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.68943979
69Neurotrophin signaling pathway_Homo sapiens_hsa047220.68010879
70Alcoholism_Homo sapiens_hsa050340.67231628
71Gap junction_Homo sapiens_hsa045400.65808164
72HTLV-I infection_Homo sapiens_hsa051660.65346026
73Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.65215353
74Colorectal cancer_Homo sapiens_hsa052100.64939315
75Non-homologous end-joining_Homo sapiens_hsa034500.62249835
76Legionellosis_Homo sapiens_hsa051340.62050467
77Glutathione metabolism_Homo sapiens_hsa004800.60434526
78N-Glycan biosynthesis_Homo sapiens_hsa005100.60390527
79Phototransduction_Homo sapiens_hsa047440.59706952
80Non-small cell lung cancer_Homo sapiens_hsa052230.59537945
81Small cell lung cancer_Homo sapiens_hsa052220.58976627
82Renal cell carcinoma_Homo sapiens_hsa052110.56544149
83Protein export_Homo sapiens_hsa030600.55506807
84Long-term potentiation_Homo sapiens_hsa047200.52541656
85Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.51847109
86Systemic lupus erythematosus_Homo sapiens_hsa053220.51840074
87Hedgehog signaling pathway_Homo sapiens_hsa043400.49485024
88Phagosome_Homo sapiens_hsa041450.47110192
89VEGF signaling pathway_Homo sapiens_hsa043700.45967298
90Arginine biosynthesis_Homo sapiens_hsa002200.44617906
91Prion diseases_Homo sapiens_hsa050200.44566072
92Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.44382590
93Endometrial cancer_Homo sapiens_hsa052130.43894901
94Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.42423636
95Pyruvate metabolism_Homo sapiens_hsa006200.42163943
96Basal transcription factors_Homo sapiens_hsa030220.38916044
97Oxidative phosphorylation_Homo sapiens_hsa001900.38674556
98Collecting duct acid secretion_Homo sapiens_hsa049660.38273594
99Thyroid hormone signaling pathway_Homo sapiens_hsa049190.37842014
100Adherens junction_Homo sapiens_hsa045200.37629761
101Apoptosis_Homo sapiens_hsa042100.37045478
102Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.36272021
103Insulin signaling pathway_Homo sapiens_hsa049100.34919860
104* Metabolic pathways_Homo sapiens_hsa011000.34671559
105Basal cell carcinoma_Homo sapiens_hsa052170.34479601
106Parkinsons disease_Homo sapiens_hsa050120.32813379
107Antigen processing and presentation_Homo sapiens_hsa046120.32804868
108Lysine degradation_Homo sapiens_hsa003100.31403940
109Acute myeloid leukemia_Homo sapiens_hsa052210.31297532
110Propanoate metabolism_Homo sapiens_hsa006400.30837135
111Estrogen signaling pathway_Homo sapiens_hsa049150.30708296
112Pathways in cancer_Homo sapiens_hsa052000.30006339
113Tight junction_Homo sapiens_hsa045300.29609109
114Huntingtons disease_Homo sapiens_hsa050160.28858929
115Fatty acid metabolism_Homo sapiens_hsa012120.28835098
116Wnt signaling pathway_Homo sapiens_hsa043100.28702808
117Focal adhesion_Homo sapiens_hsa045100.28622883
118Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.28372668
119Cardiac muscle contraction_Homo sapiens_hsa042600.27985408
120Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.27077937
121Dopaminergic synapse_Homo sapiens_hsa047280.26801152
122Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.26447598
123Salmonella infection_Homo sapiens_hsa051320.24670139
124Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.24006303
125Pancreatic cancer_Homo sapiens_hsa052120.23944876
126Alzheimers disease_Homo sapiens_hsa050100.23323956
127Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.22350788

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »