

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | cytidine metabolic process (GO:0046087) | 9.35041702 |
| 2 | cytidine catabolic process (GO:0006216) | 9.35041702 |
| 3 | cytidine deamination (GO:0009972) | 9.35041702 |
| 4 | DNA deamination (GO:0045006) | 8.79765591 |
| 5 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 8.73685630 |
| 6 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 8.32679480 |
| 7 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 4.86556638 |
| 8 | regulation of cellular amino acid metabolic process (GO:0006521) | 4.82874296 |
| 9 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 4.65249842 |
| 10 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 4.52150412 |
| 11 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 4.52150412 |
| 12 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 4.52150412 |
| 13 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 4.50228959 |
| 14 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 4.50228959 |
| 15 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 4.46312790 |
| 16 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 4.36045145 |
| 17 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 4.36045145 |
| 18 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 4.32890081 |
| 19 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 4.30143816 |
| 20 | actin nucleation (GO:0045010) | 4.27535766 |
| 21 | pyrimidine nucleoside catabolic process (GO:0046135) | 4.18382778 |
| 22 | regulation of chronic inflammatory response (GO:0002676) | 4.18134181 |
| 23 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 4.07664210 |
| 24 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 4.06164657 |
| 25 | positive regulation of defense response to virus by host (GO:0002230) | 4.01778429 |
| 26 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.97624504 |
| 27 | negative regulation of ligase activity (GO:0051352) | 3.97624504 |
| 28 | sequestering of actin monomers (GO:0042989) | 3.82258436 |
| 29 | negative regulation by host of viral transcription (GO:0043922) | 3.77687569 |
| 30 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.76903739 |
| 31 | negative regulation of viral genome replication (GO:0045071) | 3.75160415 |
| 32 | regulation of regulatory T cell differentiation (GO:0045589) | 3.73632101 |
| 33 | positive regulation of cell cycle arrest (GO:0071158) | 3.64730515 |
| 34 | protein maturation by protein folding (GO:0022417) | 3.64603558 |
| 35 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.59740855 |
| 36 | positive regulation of lamellipodium assembly (GO:0010592) | 3.59126493 |
| 37 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 3.55150791 |
| 38 | macrophage chemotaxis (GO:0048246) | 3.54465848 |
| 39 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 3.48790617 |
| 40 | platelet dense granule organization (GO:0060155) | 3.43774248 |
| 41 | iron-sulfur cluster assembly (GO:0016226) | 3.43226754 |
| 42 | metallo-sulfur cluster assembly (GO:0031163) | 3.43226754 |
| 43 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.42126546 |
| 44 | DNA damage response, signal transduction by p53 class mediator (GO:0030330) | 3.42042225 |
| 45 | positive thymic T cell selection (GO:0045059) | 3.41438555 |
| 46 | negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665) | 3.39168914 |
| 47 | regulation of cellular amine metabolic process (GO:0033238) | 3.39151934 |
| 48 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 3.38795110 |
| 49 | positive T cell selection (GO:0043368) | 3.36042199 |
| 50 | ATP synthesis coupled proton transport (GO:0015986) | 3.34544214 |
| 51 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.34544214 |
| 52 | antigen processing and presentation of peptide antigen via MHC class I (GO:0002474) | 3.34481645 |
| 53 | positive regulation of interleukin-8 secretion (GO:2000484) | 3.30621817 |
| 54 | positive regulation of natural killer cell mediated cytotoxicity (GO:0045954) | 3.30479135 |
| 55 | eosinophil chemotaxis (GO:0048245) | 3.27090581 |
| 56 | positive regulation of ligase activity (GO:0051351) | 3.25670377 |
| 57 | negative regulation of T cell apoptotic process (GO:0070233) | 3.25105455 |
| 58 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 3.21060708 |
| 59 | positive regulation of natural killer cell mediated immunity (GO:0002717) | 3.20024682 |
| 60 | DNA demethylation (GO:0080111) | 3.19852853 |
| 61 | T cell migration (GO:0072678) | 3.18770165 |
| 62 | regulation of cell cycle arrest (GO:0071156) | 3.18709945 |
| 63 | protein neddylation (GO:0045116) | 3.10527883 |
| 64 | positive regulation of gamma-delta T cell activation (GO:0046645) | 3.07149031 |
| 65 | lymphocyte chemotaxis (GO:0048247) | 3.04700581 |
| 66 | regulation of leukocyte mediated cytotoxicity (GO:0001910) | 3.03729141 |
| 67 | regulation of T cell receptor signaling pathway (GO:0050856) | 3.00409814 |
| 68 | positive regulation of cell killing (GO:0031343) | 3.00220298 |
| 69 | protein deneddylation (GO:0000338) | 2.99535598 |
| 70 | regulation of natural killer cell mediated immunity (GO:0002715) | 2.98911632 |
| 71 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 2.98911632 |
| 72 | proteasome assembly (GO:0043248) | 2.97946398 |
| 73 | purine deoxyribonucleotide catabolic process (GO:0009155) | 2.96055279 |
| 74 | negative regulation of antigen receptor-mediated signaling pathway (GO:0050858) | 2.95786711 |
| 75 | cullin deneddylation (GO:0010388) | 2.94813375 |
| 76 | eosinophil migration (GO:0072677) | 2.94572710 |
| 77 | regulation of B cell receptor signaling pathway (GO:0050855) | 2.93777564 |
| 78 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 2.93224451 |
| 79 | pyrimidine-containing compound catabolic process (GO:0072529) | 2.90291145 |
| 80 | response to interferon-beta (GO:0035456) | 2.89591822 |
| 81 | post-embryonic morphogenesis (GO:0009886) | 2.88482714 |
| 82 | negative regulation of cell cycle G1/S phase transition (GO:1902807) | 2.87443745 |
| 83 | negative regulation of G1/S transition of mitotic cell cycle (GO:2000134) | 2.87443745 |
| 84 | L-methionine biosynthetic process (GO:0071265) | 2.86888201 |
| 85 | amino acid salvage (GO:0043102) | 2.86888201 |
| 86 | L-methionine salvage (GO:0071267) | 2.86888201 |
| 87 | signal transduction in response to DNA damage (GO:0042770) | 2.84166111 |
| 88 | positive regulation of tolerance induction (GO:0002645) | 2.83844474 |
| 89 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 2.82498118 |
| 90 | respiratory electron transport chain (GO:0022904) | 2.82342044 |
| 91 | regulation of cell killing (GO:0031341) | 2.82325301 |
| 92 | detection of chemical stimulus involved in sensory perception of bitter taste (GO:0001580) | 2.81122027 |
| 93 | natural killer cell activation (GO:0030101) | 2.79076304 |
| 94 | regulation of isotype switching to IgG isotypes (GO:0048302) | 2.78318536 |
| 95 | regulation of antigen receptor-mediated signaling pathway (GO:0050854) | 2.78186239 |
| 96 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 2.77715712 |
| 97 | regulation of viral genome replication (GO:0045069) | 2.77712252 |
| 98 | DNA dealkylation (GO:0035510) | 2.77375474 |
| 99 | positive regulation of calcium-mediated signaling (GO:0050850) | 2.76666806 |
| 100 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.76348422 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 5.27799539 |
| 2 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 4.99202396 |
| 3 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.75921733 |
| 4 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.73367933 |
| 5 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.61499935 |
| 6 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 3.59247126 |
| 7 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.30153708 |
| 8 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.18262816 |
| 9 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.94727871 |
| 10 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.91662628 |
| 11 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.55990837 |
| 12 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.53369913 |
| 13 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.45779429 |
| 14 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.40403059 |
| 15 | MYB_26560356_Chip-Seq_TH2_Human | 2.35726455 |
| 16 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 2.28849382 |
| 17 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 2.26450035 |
| 18 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.21276306 |
| 19 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.19677707 |
| 20 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.18822783 |
| 21 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.99978913 |
| 22 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.98006871 |
| 23 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.97156940 |
| 24 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.93212985 |
| 25 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.91114557 |
| 26 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.83521490 |
| 27 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.81979985 |
| 28 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.79723208 |
| 29 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.78653547 |
| 30 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.77066724 |
| 31 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.71532872 |
| 32 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.64766847 |
| 33 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.62765869 |
| 34 | VDR_22108803_ChIP-Seq_LS180_Human | 1.59790490 |
| 35 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.59463896 |
| 36 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.58062430 |
| 37 | GATA3_26560356_Chip-Seq_TH2_Human | 1.57876025 |
| 38 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.56659525 |
| 39 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.52196762 |
| 40 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.50969841 |
| 41 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.49378124 |
| 42 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.46697653 |
| 43 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.45375818 |
| 44 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.42516544 |
| 45 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.41847245 |
| 46 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.39186370 |
| 47 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.38271971 |
| 48 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.37707030 |
| 49 | CTCF_20526341_ChIP-Seq_ESCs_Human | 1.36891246 |
| 50 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.33935502 |
| 51 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.33478227 |
| 52 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.31623325 |
| 53 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.30698021 |
| 54 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.29753044 |
| 55 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.29509069 |
| 56 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.27636416 |
| 57 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.25027457 |
| 58 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.24767677 |
| 59 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.24333590 |
| 60 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.22663704 |
| 61 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.22649168 |
| 62 | MYB_26560356_Chip-Seq_TH1_Human | 1.21481293 |
| 63 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.21400289 |
| 64 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.20627878 |
| 65 | MAF_26560356_Chip-Seq_TH1_Human | 1.20333704 |
| 66 | UTX_26944678_Chip-Seq_JUKART_Human | 1.20186475 |
| 67 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.17284553 |
| 68 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.16793695 |
| 69 | MAF_26560356_Chip-Seq_TH2_Human | 1.14451590 |
| 70 | P300_27268052_Chip-Seq_Bcells_Human | 1.14060041 |
| 71 | BCOR_27268052_Chip-Seq_Bcells_Human | 1.13537816 |
| 72 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.10182463 |
| 73 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.09832515 |
| 74 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.07052199 |
| 75 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.06310032 |
| 76 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.05587779 |
| 77 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.04362657 |
| 78 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.03822613 |
| 79 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.02129219 |
| 80 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.01687070 |
| 81 | ERA_21632823_ChIP-Seq_H3396_Human | 1.01540813 |
| 82 | E2F1_20622854_ChIP-Seq_HELA_Human | 0.99542560 |
| 83 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 0.99280639 |
| 84 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.97407997 |
| 85 | SPI1_23547873_ChIP-Seq_NB4_Human | 0.97330410 |
| 86 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 0.94341581 |
| 87 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 0.94287435 |
| 88 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 0.94024861 |
| 89 | AR_20517297_ChIP-Seq_VCAP_Human | 0.93952824 |
| 90 | RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.92389255 |
| 91 | SA1_27219007_Chip-Seq_Bcells_Human | 0.92370094 |
| 92 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.91269232 |
| 93 | GATA3_26560356_Chip-Seq_TH1_Human | 0.89740560 |
| 94 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 0.89207858 |
| 95 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.88956171 |
| 96 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.88956171 |
| 97 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.88191542 |
| 98 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 0.87567773 |
| 99 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 0.87159315 |
| 100 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.84278594 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005671_abnormal_response_to | 6.69262212 |
| 2 | MP0009785_altered_susceptibility_to | 3.13911813 |
| 3 | MP0006072_abnormal_retinal_apoptosis | 2.97509010 |
| 4 | MP0001835_abnormal_antigen_presentation | 2.89507590 |
| 5 | MP0009333_abnormal_splenocyte_physiolog | 2.78454760 |
| 6 | MP0000685_abnormal_immune_system | 2.56245160 |
| 7 | MP0003011_delayed_dark_adaptation | 2.54874511 |
| 8 | MP0003763_abnormal_thymus_physiology | 2.47894038 |
| 9 | MP0000372_irregular_coat_pigmentation | 2.44670070 |
| 10 | MP0002166_altered_tumor_susceptibility | 2.43178905 |
| 11 | MP0002102_abnormal_ear_morphology | 2.42770144 |
| 12 | MP0001873_stomach_inflammation | 2.35631255 |
| 13 | MP0002148_abnormal_hypersensitivity_rea | 2.20860157 |
| 14 | MP0005025_abnormal_response_to | 2.07275005 |
| 15 | MP0002006_tumorigenesis | 2.03002885 |
| 16 | MP0001800_abnormal_humoral_immune | 1.96281158 |
| 17 | MP0006082_CNS_inflammation | 1.95989566 |
| 18 | MP0001986_abnormal_taste_sensitivity | 1.94547356 |
| 19 | MP0005000_abnormal_immune_tolerance | 1.94278911 |
| 20 | MP0002277_abnormal_respiratory_mucosa | 1.89869397 |
| 21 | MP0002723_abnormal_immune_serum | 1.76464890 |
| 22 | MP0002420_abnormal_adaptive_immunity | 1.76101383 |
| 23 | MP0003866_abnormal_defecation | 1.73278674 |
| 24 | MP0001905_abnormal_dopamine_level | 1.71297821 |
| 25 | MP0001819_abnormal_immune_cell | 1.67876212 |
| 26 | MP0005387_immune_system_phenotype | 1.67115377 |
| 27 | MP0001790_abnormal_immune_system | 1.67115377 |
| 28 | MP0003806_abnormal_nucleotide_metabolis | 1.54588440 |
| 29 | MP0001501_abnormal_sleep_pattern | 1.51563514 |
| 30 | MP0004145_abnormal_muscle_electrophysio | 1.50991511 |
| 31 | MP0006276_abnormal_autonomic_nervous | 1.48024393 |
| 32 | MP0002822_catalepsy | 1.45992443 |
| 33 | MP0008058_abnormal_DNA_repair | 1.45083839 |
| 34 | MP0004147_increased_porphyrin_level | 1.45072868 |
| 35 | MP0003786_premature_aging | 1.44775540 |
| 36 | MP0005253_abnormal_eye_physiology | 1.43751920 |
| 37 | MP0000716_abnormal_immune_system | 1.41056459 |
| 38 | MP0009764_decreased_sensitivity_to | 1.37525192 |
| 39 | MP0002452_abnormal_antigen_presenting | 1.36760813 |
| 40 | MP0001919_abnormal_reproductive_system | 1.35315975 |
| 41 | MP0002398_abnormal_bone_marrow | 1.33876562 |
| 42 | MP0002405_respiratory_system_inflammati | 1.30505122 |
| 43 | MP0006036_abnormal_mitochondrial_physio | 1.26859611 |
| 44 | MP0008872_abnormal_physiological_respon | 1.26166749 |
| 45 | MP0008875_abnormal_xenobiotic_pharmacok | 1.25617064 |
| 46 | MP0002736_abnormal_nociception_after | 1.25372391 |
| 47 | MP0010155_abnormal_intestine_physiology | 1.23702416 |
| 48 | MP0003195_calcinosis | 1.22573860 |
| 49 | MP0000703_abnormal_thymus_morphology | 1.21500809 |
| 50 | MP0009745_abnormal_behavioral_response | 1.21091594 |
| 51 | MP0003646_muscle_fatigue | 1.21091198 |
| 52 | MP0004510_myositis | 1.20079524 |
| 53 | MP0002876_abnormal_thyroid_physiology | 1.19262285 |
| 54 | MP0002095_abnormal_skin_pigmentation | 1.17323661 |
| 55 | MP0005423_abnormal_somatic_nervous | 1.17290599 |
| 56 | MP0001984_abnormal_olfaction | 1.15895194 |
| 57 | MP0000689_abnormal_spleen_morphology | 1.11655301 |
| 58 | MP0001845_abnormal_inflammatory_respons | 1.10439255 |
| 59 | MP0008469_abnormal_protein_level | 1.10206913 |
| 60 | MP0002722_abnormal_immune_system | 1.08326313 |
| 61 | MP0002429_abnormal_blood_cell | 1.07806156 |
| 62 | MP0001968_abnormal_touch/_nociception | 1.07690982 |
| 63 | MP0001529_abnormal_vocalization | 1.05631114 |
| 64 | MP0001542_abnormal_bone_strength | 1.04120214 |
| 65 | MP0008789_abnormal_olfactory_epithelium | 1.03426435 |
| 66 | MP0002254_reproductive_system_inflammat | 1.02987816 |
| 67 | MP0003448_altered_tumor_morphology | 1.02550504 |
| 68 | MP0008995_early_reproductive_senescence | 1.00726103 |
| 69 | MP0001853_heart_inflammation | 0.98677422 |
| 70 | MP0002933_joint_inflammation | 0.96640965 |
| 71 | MP0009697_abnormal_copulation | 0.96294769 |
| 72 | MP0002019_abnormal_tumor_incidence | 0.96254782 |
| 73 | MP0001119_abnormal_female_reproductive | 0.95180567 |
| 74 | MP0000490_abnormal_crypts_of | 0.93775370 |
| 75 | MP0006035_abnormal_mitochondrial_morpho | 0.91454168 |
| 76 | MP0003137_abnormal_impulse_conducting | 0.89588304 |
| 77 | MP0001188_hyperpigmentation | 0.89338162 |
| 78 | MP0005636_abnormal_mineral_homeostasis | 0.89140429 |
| 79 | MP0004947_skin_inflammation | 0.88301606 |
| 80 | MP0009763_increased_sensitivity_to | 0.87450230 |
| 81 | MP0005551_abnormal_eye_electrophysiolog | 0.85333405 |
| 82 | MP0005166_decreased_susceptibility_to | 0.84445300 |
| 83 | MP0003878_abnormal_ear_physiology | 0.83728481 |
| 84 | MP0005377_hearing/vestibular/ear_phenot | 0.83728481 |
| 85 | MP0005257_abnormal_intraocular_pressure | 0.83230185 |
| 86 | MP0002733_abnormal_thermal_nociception | 0.81821408 |
| 87 | MP0002419_abnormal_innate_immunity | 0.79089817 |
| 88 | MP0004270_analgesia | 0.78762673 |
| 89 | MP0003638_abnormal_response/metabolism_ | 0.74413846 |
| 90 | MP0003724_increased_susceptibility_to | 0.73431208 |
| 91 | MP0005645_abnormal_hypothalamus_physiol | 0.72781792 |
| 92 | MP0002751_abnormal_autonomic_nervous | 0.72131469 |
| 93 | MP0005389_reproductive_system_phenotype | 0.71889447 |
| 94 | MP0005085_abnormal_gallbladder_physiolo | 0.71886257 |
| 95 | MP0002210_abnormal_sex_determination | 0.70654731 |
| 96 | MP0005408_hypopigmentation | 0.68709700 |
| 97 | MP0000858_altered_metastatic_potential | 0.64382198 |
| 98 | MP0000639_abnormal_adrenal_gland | 0.64271278 |
| 99 | MP0003436_decreased_susceptibility_to | 0.62543697 |
| 100 | MP0005584_abnormal_enzyme/coenzyme_acti | 0.61503282 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Aplastic anemia (HP:0001915) | 5.97252671 |
| 2 | T lymphocytopenia (HP:0005403) | 4.50968821 |
| 3 | IgG deficiency (HP:0004315) | 4.27836402 |
| 4 | Abnormality of T cell number (HP:0011839) | 4.04171542 |
| 5 | Congenital stationary night blindness (HP:0007642) | 3.97550470 |
| 6 | Hepatocellular necrosis (HP:0001404) | 3.94769271 |
| 7 | Elevated erythrocyte sedimentation rate (HP:0003565) | 3.94133760 |
| 8 | Increased intramyocellular lipid droplets (HP:0012240) | 3.76842960 |
| 9 | Mitochondrial inheritance (HP:0001427) | 3.74899226 |
| 10 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.65533739 |
| 11 | Acute necrotizing encephalopathy (HP:0006965) | 3.63008605 |
| 12 | Hepatic necrosis (HP:0002605) | 3.45953375 |
| 13 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 3.43974862 |
| 14 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 3.43974862 |
| 15 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 3.36148707 |
| 16 | 3-Methylglutaconic aciduria (HP:0003535) | 3.29832216 |
| 17 | Increased CSF lactate (HP:0002490) | 3.19756106 |
| 18 | Aplasia/hypoplasia of the uterus (HP:0008684) | 3.11465078 |
| 19 | Increased muscle lipid content (HP:0009058) | 3.05585296 |
| 20 | Severe combined immunodeficiency (HP:0004430) | 3.04328375 |
| 21 | Abnormality of T cells (HP:0002843) | 2.96978503 |
| 22 | Hypoproteinemia (HP:0003075) | 2.93481809 |
| 23 | Progressive macrocephaly (HP:0004481) | 2.86913160 |
| 24 | Increased IgM level (HP:0003496) | 2.85778304 |
| 25 | Increased hepatocellular lipid droplets (HP:0006565) | 2.81331697 |
| 26 | Acute encephalopathy (HP:0006846) | 2.80459971 |
| 27 | Recurrent bronchitis (HP:0002837) | 2.73539555 |
| 28 | Autoimmune hemolytic anemia (HP:0001890) | 2.68534678 |
| 29 | Renal Fanconi syndrome (HP:0001994) | 2.64463715 |
| 30 | Agammaglobulinemia (HP:0004432) | 2.63048634 |
| 31 | Pancreatic cysts (HP:0001737) | 2.56212683 |
| 32 | Abnormality of eosinophils (HP:0001879) | 2.55425768 |
| 33 | Stomatitis (HP:0010280) | 2.49690663 |
| 34 | Chronic diarrhea (HP:0002028) | 2.47788698 |
| 35 | Increased serum lactate (HP:0002151) | 2.45940815 |
| 36 | Microretrognathia (HP:0000308) | 2.45742560 |
| 37 | Delayed CNS myelination (HP:0002188) | 2.45375787 |
| 38 | Palpebral edema (HP:0100540) | 2.44887174 |
| 39 | Anhidrosis (HP:0000970) | 2.44738651 |
| 40 | Hypoplasia of the uterus (HP:0000013) | 2.44053431 |
| 41 | Lipid accumulation in hepatocytes (HP:0006561) | 2.42941064 |
| 42 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.41809715 |
| 43 | Reduced subcutaneous adipose tissue (HP:0003758) | 2.37536620 |
| 44 | Optic disc pallor (HP:0000543) | 2.32826292 |
| 45 | Thyroiditis (HP:0100646) | 2.32799920 |
| 46 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.32072197 |
| 47 | Exercise intolerance (HP:0003546) | 2.29487377 |
| 48 | Emotional lability (HP:0000712) | 2.25981202 |
| 49 | Cerebral edema (HP:0002181) | 2.22935497 |
| 50 | Type I transferrin isoform profile (HP:0003642) | 2.20817437 |
| 51 | Combined immunodeficiency (HP:0005387) | 2.20493590 |
| 52 | Eosinophilia (HP:0001880) | 2.19518656 |
| 53 | Orthostatic hypotension (HP:0001278) | 2.17226728 |
| 54 | Arthropathy (HP:0003040) | 2.16491300 |
| 55 | Abnormality of the prostate (HP:0008775) | 2.16008271 |
| 56 | Dysautonomia (HP:0002459) | 2.14528620 |
| 57 | Fibular aplasia (HP:0002990) | 2.11439592 |
| 58 | Lactic acidosis (HP:0003128) | 2.11052950 |
| 59 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.10101203 |
| 60 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.10101203 |
| 61 | Abnormal protein glycosylation (HP:0012346) | 2.10101203 |
| 62 | Abnormal glycosylation (HP:0012345) | 2.10101203 |
| 63 | Respiratory failure (HP:0002878) | 2.09313752 |
| 64 | Posterior subcapsular cataract (HP:0007787) | 2.03184919 |
| 65 | Oral leukoplakia (HP:0002745) | 2.02693646 |
| 66 | Exertional dyspnea (HP:0002875) | 2.01806073 |
| 67 | Chronic mucocutaneous candidiasis (HP:0002728) | 1.98013356 |
| 68 | Recurrent cutaneous fungal infections (HP:0011370) | 1.98013356 |
| 69 | Encephalitis (HP:0002383) | 1.97756457 |
| 70 | Recurrent corneal erosions (HP:0000495) | 1.94795989 |
| 71 | Severe visual impairment (HP:0001141) | 1.94582474 |
| 72 | Adactyly (HP:0009776) | 1.91431409 |
| 73 | Radial bowing (HP:0002986) | 1.87807107 |
| 74 | Hydroureter (HP:0000072) | 1.86835383 |
| 75 | Tongue fasciculations (HP:0001308) | 1.84892931 |
| 76 | Lymphopenia (HP:0001888) | 1.84020559 |
| 77 | Bronchitis (HP:0012387) | 1.83491357 |
| 78 | Cerebral palsy (HP:0100021) | 1.83103387 |
| 79 | Reduced antithrombin III activity (HP:0001976) | 1.82809021 |
| 80 | Abnormal albumin level (HP:0012116) | 1.82354780 |
| 81 | Hypoalbuminemia (HP:0003073) | 1.82354780 |
| 82 | Glucose intolerance (HP:0000833) | 1.82106621 |
| 83 | X-linked dominant inheritance (HP:0001423) | 1.81208103 |
| 84 | IgM deficiency (HP:0002850) | 1.80848456 |
| 85 | Gastrointestinal infarctions (HP:0005244) | 1.78813533 |
| 86 | Pancytopenia (HP:0001876) | 1.78376055 |
| 87 | Sensorimotor neuropathy (HP:0007141) | 1.76792552 |
| 88 | Progressive inability to walk (HP:0002505) | 1.76610490 |
| 89 | Amyotrophic lateral sclerosis (HP:0007354) | 1.76234740 |
| 90 | Conical tooth (HP:0000698) | 1.75572465 |
| 91 | Recurrent otitis media (HP:0000403) | 1.75320161 |
| 92 | Cerebral hypomyelination (HP:0006808) | 1.75260087 |
| 93 | B lymphocytopenia (HP:0010976) | 1.75042842 |
| 94 | Leukocytosis (HP:0001974) | 1.73925967 |
| 95 | Oligomenorrhea (HP:0000876) | 1.73616902 |
| 96 | Limb dystonia (HP:0002451) | 1.71624543 |
| 97 | Atrophy/Degeneration involving motor neurons (HP:0007373) | 1.70884826 |
| 98 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 1.69886995 |
| 99 | Hypoplastic pelvis (HP:0008839) | 1.68984181 |
| 100 | Abnormality of macrophages (HP:0004311) | 1.68389322 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TESK2 | 9.86683752 |
| 2 | TXK | 4.32571112 |
| 3 | KDR | 4.09768888 |
| 4 | ZAK | 3.70584488 |
| 5 | TESK1 | 3.18455054 |
| 6 | TLK1 | 3.06250684 |
| 7 | MAP4K2 | 2.64355529 |
| 8 | LIMK1 | 2.29194474 |
| 9 | GRK1 | 2.26769831 |
| 10 | VRK2 | 2.14245269 |
| 11 | DAPK1 | 1.91258304 |
| 12 | MST4 | 1.86685065 |
| 13 | VRK1 | 1.85987082 |
| 14 | MAPKAPK3 | 1.85240769 |
| 15 | MAP3K12 | 1.81682072 |
| 16 | TRIM28 | 1.52434545 |
| 17 | SRPK1 | 1.52274233 |
| 18 | BCKDK | 1.48347164 |
| 19 | MATK | 1.24872653 |
| 20 | LMTK2 | 1.23805116 |
| 21 | NTRK1 | 1.19477587 |
| 22 | CSNK1G3 | 1.18949301 |
| 23 | CSNK1A1L | 1.09870245 |
| 24 | NUAK1 | 1.09165564 |
| 25 | RPS6KA4 | 0.99165314 |
| 26 | SIK3 | 0.97738971 |
| 27 | CSNK1G1 | 0.97363081 |
| 28 | TNK2 | 0.95873846 |
| 29 | MAP4K1 | 0.95338074 |
| 30 | NME1 | 0.92259821 |
| 31 | CSNK1G2 | 0.88638831 |
| 32 | MYLK | 0.86872955 |
| 33 | AURKA | 0.84550999 |
| 34 | FES | 0.83212420 |
| 35 | ITK | 0.81306536 |
| 36 | SYK | 0.74499524 |
| 37 | PHKG2 | 0.72039418 |
| 38 | PHKG1 | 0.72039418 |
| 39 | GRK7 | 0.69028394 |
| 40 | BUB1 | 0.68798749 |
| 41 | CSK | 0.67882882 |
| 42 | MAP2K7 | 0.65872891 |
| 43 | NME2 | 0.64102470 |
| 44 | CAMKK2 | 0.64096623 |
| 45 | LCK | 0.60373253 |
| 46 | ADRBK2 | 0.60024282 |
| 47 | BMPR2 | 0.59754463 |
| 48 | CDK19 | 0.56276093 |
| 49 | PAK1 | 0.55033965 |
| 50 | ZAP70 | 0.54945611 |
| 51 | RPS6KA5 | 0.52411806 |
| 52 | STK16 | 0.50937510 |
| 53 | WNK4 | 0.48486380 |
| 54 | ARAF | 0.47631281 |
| 55 | TAOK3 | 0.47532577 |
| 56 | ROCK1 | 0.46306344 |
| 57 | PAK6 | 0.45560417 |
| 58 | PRKCI | 0.43524118 |
| 59 | EIF2AK1 | 0.43495244 |
| 60 | IKBKB | 0.42009421 |
| 61 | PRKCQ | 0.41620273 |
| 62 | MAP3K11 | 0.40936369 |
| 63 | INSRR | 0.40261348 |
| 64 | EIF2AK3 | 0.39689277 |
| 65 | MOS | 0.38894062 |
| 66 | GRK6 | 0.38815834 |
| 67 | LYN | 0.35792497 |
| 68 | IGF1R | 0.34139282 |
| 69 | PIM2 | 0.33584595 |
| 70 | BCR | 0.32039049 |
| 71 | FYN | 0.31338975 |
| 72 | IKBKE | 0.31159170 |
| 73 | GRK5 | 0.31080972 |
| 74 | CSNK1A1 | 0.30442321 |
| 75 | ATR | 0.30346798 |
| 76 | WNK3 | 0.29994544 |
| 77 | CSNK2A1 | 0.27156490 |
| 78 | AKT3 | 0.26718050 |
| 79 | ERBB2 | 0.26187952 |
| 80 | INSR | 0.26088567 |
| 81 | SCYL2 | 0.24874261 |
| 82 | EIF2AK2 | 0.24613043 |
| 83 | TIE1 | 0.24432085 |
| 84 | STK39 | 0.24209563 |
| 85 | PRKCE | 0.23451980 |
| 86 | BRSK1 | 0.22877467 |
| 87 | PLK3 | 0.22802720 |
| 88 | ERBB3 | 0.22288680 |
| 89 | MAPK11 | 0.21262895 |
| 90 | RAF1 | 0.21239559 |
| 91 | CASK | 0.20763630 |
| 92 | PRKACA | 0.20611962 |
| 93 | MAPKAPK2 | 0.20560153 |
| 94 | PRKCA | 0.20524443 |
| 95 | CAMK2G | 0.19406528 |
| 96 | KIT | 0.19337822 |
| 97 | OBSCN | 0.19249778 |
| 98 | STK10 | 0.17439864 |
| 99 | PAK4 | 0.16466799 |
| 100 | OXSR1 | 0.16312669 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 6.76080206 |
| 2 | Primary immunodeficiency_Homo sapiens_hsa05340 | 4.74053782 |
| 3 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.31746117 |
| 4 | Parkinsons disease_Homo sapiens_hsa05012 | 2.79567065 |
| 5 | Antigen processing and presentation_Homo sapiens_hsa04612 | 2.61455096 |
| 6 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.51132777 |
| 7 | Protein export_Homo sapiens_hsa03060 | 2.38475394 |
| 8 | RNA polymerase_Homo sapiens_hsa03020 | 2.30328542 |
| 9 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 2.05720877 |
| 10 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 2.03294137 |
| 11 | Alzheimers disease_Homo sapiens_hsa05010 | 1.78288044 |
| 12 | Huntingtons disease_Homo sapiens_hsa05016 | 1.71073606 |
| 13 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.69868140 |
| 14 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.60081853 |
| 15 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.60040189 |
| 16 | Allograft rejection_Homo sapiens_hsa05330 | 1.51986272 |
| 17 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.51404010 |
| 18 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 1.50136944 |
| 19 | Phototransduction_Homo sapiens_hsa04744 | 1.49728709 |
| 20 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.40457826 |
| 21 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.40362554 |
| 22 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.39427122 |
| 23 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.29056025 |
| 24 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.28807232 |
| 25 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.27473194 |
| 26 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 1.21996699 |
| 27 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.20081732 |
| 28 | Shigellosis_Homo sapiens_hsa05131 | 1.18219590 |
| 29 | DNA replication_Homo sapiens_hsa03030 | 1.14262826 |
| 30 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.13585908 |
| 31 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.13438279 |
| 32 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.11842843 |
| 33 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.11681653 |
| 34 | Asthma_Homo sapiens_hsa05310 | 1.08613546 |
| 35 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.06730201 |
| 36 | Viral myocarditis_Homo sapiens_hsa05416 | 1.03474213 |
| 37 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.01031086 |
| 38 | Peroxisome_Homo sapiens_hsa04146 | 0.98334335 |
| 39 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.97725717 |
| 40 | Ribosome_Homo sapiens_hsa03010 | 0.91830232 |
| 41 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.91600820 |
| 42 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.90596788 |
| 43 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.90559222 |
| 44 | Sulfur relay system_Homo sapiens_hsa04122 | 0.89698546 |
| 45 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.87488115 |
| 46 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.85690148 |
| 47 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.82894127 |
| 48 | Mismatch repair_Homo sapiens_hsa03430 | 0.81517356 |
| 49 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.79705258 |
| 50 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.79029078 |
| 51 | RNA degradation_Homo sapiens_hsa03018 | 0.78802109 |
| 52 | Spliceosome_Homo sapiens_hsa03040 | 0.78504551 |
| 53 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.76970774 |
| 54 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.73138255 |
| 55 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.72798263 |
| 56 | Salmonella infection_Homo sapiens_hsa05132 | 0.70220061 |
| 57 | Measles_Homo sapiens_hsa05162 | 0.70003052 |
| 58 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.69983375 |
| 59 | Base excision repair_Homo sapiens_hsa03410 | 0.68360219 |
| 60 | Homologous recombination_Homo sapiens_hsa03440 | 0.67746337 |
| 61 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.66841963 |
| 62 | Basal transcription factors_Homo sapiens_hsa03022 | 0.65214757 |
| 63 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.65042273 |
| 64 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.64966218 |
| 65 | Purine metabolism_Homo sapiens_hsa00230 | 0.63623860 |
| 66 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.63203852 |
| 67 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.62813122 |
| 68 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.62562691 |
| 69 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.61176769 |
| 70 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.60729337 |
| 71 | Carbon metabolism_Homo sapiens_hsa01200 | 0.59947006 |
| 72 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.56870380 |
| 73 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.54363481 |
| 74 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.54165505 |
| 75 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.53226606 |
| 76 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.52337777 |
| 77 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.49276092 |
| 78 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.48481778 |
| 79 | Metabolic pathways_Homo sapiens_hsa01100 | 0.47544652 |
| 80 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.47037696 |
| 81 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.44614846 |
| 82 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.44040986 |
| 83 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.39386459 |
| 84 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.38967726 |
| 85 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.36974921 |
| 86 | Retinol metabolism_Homo sapiens_hsa00830 | 0.36945454 |
| 87 | RNA transport_Homo sapiens_hsa03013 | 0.36125196 |
| 88 | Taste transduction_Homo sapiens_hsa04742 | 0.35816466 |
| 89 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.35749864 |
| 90 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.32101272 |
| 91 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.31623990 |
| 92 | Salivary secretion_Homo sapiens_hsa04970 | 0.30561273 |
| 93 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.29784407 |
| 94 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.25427232 |
| 95 | Morphine addiction_Homo sapiens_hsa05032 | 0.25354152 |
| 96 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.24765490 |
| 97 | Legionellosis_Homo sapiens_hsa05134 | 0.24015723 |
| 98 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.23480424 |
| 99 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.23203892 |
| 100 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.21633661 |

