Rank | Gene Set | Z-score |
---|---|---|
1 | DNA unwinding involved in DNA replication (GO:0006268) | 6.06289748 |
2 | glucose 6-phosphate metabolic process (GO:0051156) | 5.69753931 |
3 | positive regulation of mitochondrial fission (GO:0090141) | 5.43999854 |
4 | folic acid-containing compound biosynthetic process (GO:0009396) | 5.33444028 |
5 | IMP biosynthetic process (GO:0006188) | 5.14007729 |
6 | nuclear pore organization (GO:0006999) | 5.06031527 |
7 | protein localization to kinetochore (GO:0034501) | 4.86330620 |
8 | regulation of translational fidelity (GO:0006450) | 4.77710204 |
9 | IMP metabolic process (GO:0046040) | 4.75519868 |
10 | * glycolytic process (GO:0006096) | 4.70263869 |
11 | establishment of viral latency (GO:0019043) | 4.66452508 |
12 | nuclear pore complex assembly (GO:0051292) | 4.58590023 |
13 | mitochondrial fragmentation involved in apoptotic process (GO:0043653) | 4.58277972 |
14 | positive regulation of mitochondrial membrane permeability involved in apoptotic process (GO:1902110 | 4.46695250 |
15 | mitochondrial outer membrane permeabilization involved in programmed cell death (GO:1902686) | 4.46695250 |
16 | regulation of translational termination (GO:0006449) | 4.32765775 |
17 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 4.32630042 |
18 | heterochromatin organization (GO:0070828) | 4.28052019 |
19 | formation of translation preinitiation complex (GO:0001731) | 4.23135881 |
20 | 4-hydroxyproline metabolic process (GO:0019471) | 4.20949840 |
21 | protein maturation by protein folding (GO:0022417) | 4.17120545 |
22 | mitotic nuclear envelope disassembly (GO:0007077) | 4.14277080 |
23 | pentose-phosphate shunt (GO:0006098) | 4.13686976 |
24 | maintenance of protein localization in endoplasmic reticulum (GO:0035437) | 4.05154411 |
25 | mitotic chromosome condensation (GO:0007076) | 4.02698315 |
26 | sister chromatid segregation (GO:0000819) | 3.93245717 |
27 | nuclear envelope disassembly (GO:0051081) | 3.92887877 |
28 | membrane disassembly (GO:0030397) | 3.92887877 |
29 | retrograde vesicle-mediated transport, Golgi to ER (GO:0006890) | 3.91338588 |
30 | peptidyl-arginine omega-N-methylation (GO:0035247) | 3.90739198 |
31 | protein retention in ER lumen (GO:0006621) | 3.90669431 |
32 | nucleobase biosynthetic process (GO:0046112) | 3.90152496 |
33 | mitotic sister chromatid segregation (GO:0000070) | 3.84838533 |
34 | cholesterol biosynthetic process (GO:0006695) | 3.83128011 |
35 | protein hydroxylation (GO:0018126) | 3.78291779 |
36 | peptidyl-proline hydroxylation (GO:0019511) | 3.72388942 |
37 | NADPH regeneration (GO:0006740) | 3.70962811 |
38 | DNA replication initiation (GO:0006270) | 3.70924709 |
39 | regulation of mitochondrial fission (GO:0090140) | 3.64215968 |
40 | regulation of posttranscriptional gene silencing (GO:0060147) | 3.62688363 |
41 | regulation of gene silencing by miRNA (GO:0060964) | 3.62688363 |
42 | regulation of gene silencing by RNA (GO:0060966) | 3.62688363 |
43 | protein localization to chromosome, centromeric region (GO:0071459) | 3.59701574 |
44 | tricarboxylic acid cycle (GO:0006099) | 3.57719735 |
45 | purine nucleobase biosynthetic process (GO:0009113) | 3.56002515 |
46 | regulation of attachment of spindle microtubules to kinetochore (GO:0051988) | 3.55663132 |
47 | peptidyl-lysine dimethylation (GO:0018027) | 3.54759803 |
48 | DNA strand elongation involved in DNA replication (GO:0006271) | 3.52196285 |
49 | nuclear envelope reassembly (GO:0031468) | 3.50926543 |
50 | mitotic nuclear envelope reassembly (GO:0007084) | 3.50926543 |
51 | DNA geometric change (GO:0032392) | 3.50828149 |
52 | regulation of coenzyme metabolic process (GO:0051196) | 3.50756061 |
53 | regulation of cofactor metabolic process (GO:0051193) | 3.50756061 |
54 | DNA duplex unwinding (GO:0032508) | 3.50435312 |
55 | de novo posttranslational protein folding (GO:0051084) | 3.48045696 |
56 | L-serine metabolic process (GO:0006563) | 3.45950100 |
57 | DNA replication-dependent nucleosome assembly (GO:0006335) | 3.45485535 |
58 | DNA replication-dependent nucleosome organization (GO:0034723) | 3.45485535 |
59 | de novo protein folding (GO:0006458) | 3.42257203 |
60 | pre-miRNA processing (GO:0031054) | 3.40649819 |
61 | peptidyl-arginine N-methylation (GO:0035246) | 3.40230906 |
62 | peptidyl-arginine methylation (GO:0018216) | 3.40230906 |
63 | chaperone-mediated protein complex assembly (GO:0051131) | 3.40212258 |
64 | * pyruvate metabolic process (GO:0006090) | 3.39258063 |
65 | mitochondrial fission (GO:0000266) | 3.34297456 |
66 | regulation of Arp2/3 complex-mediated actin nucleation (GO:0034315) | 3.32479141 |
67 | sterol biosynthetic process (GO:0016126) | 3.31507938 |
68 | histone arginine methylation (GO:0034969) | 3.28781972 |
69 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 3.28239578 |
70 | DNA strand elongation (GO:0022616) | 3.26000437 |
71 | pore complex assembly (GO:0046931) | 3.24828141 |
72 | fructose metabolic process (GO:0006000) | 3.24788216 |
73 | mitotic metaphase plate congression (GO:0007080) | 3.23200970 |
74 | proline biosynthetic process (GO:0006561) | 3.20266423 |
75 | spliceosomal tri-snRNP complex assembly (GO:0000244) | 3.18485540 |
76 | tRNA aminoacylation for protein translation (GO:0006418) | 3.15211875 |
77 | tetrahydrofolate metabolic process (GO:0046653) | 3.11007767 |
78 | oxaloacetate metabolic process (GO:0006107) | 3.10950719 |
79 | postreplication repair (GO:0006301) | 3.10894553 |
80 | * single-organism carbohydrate catabolic process (GO:0044724) | 3.10438520 |
81 | * gluconeogenesis (GO:0006094) | 3.08674946 |
82 | nuclear envelope organization (GO:0006998) | 3.07877060 |
83 | chromatin assembly (GO:0031497) | 3.07651250 |
84 | negative regulation of histone methylation (GO:0031061) | 3.06404116 |
85 | regulation of protein heterodimerization activity (GO:0043497) | 3.04509329 |
86 | positive regulation of SMAD protein import into nucleus (GO:0060391) | 3.02976592 |
87 | positive regulation of receptor biosynthetic process (GO:0010870) | 3.01960492 |
88 | tRNA aminoacylation (GO:0043039) | 3.01131811 |
89 | amino acid activation (GO:0043038) | 3.01131811 |
90 | regulation of spindle organization (GO:0090224) | 3.00901438 |
91 | regulation of histone H3-K9 methylation (GO:0051570) | 3.00404805 |
92 | dosage compensation (GO:0007549) | 2.98385382 |
93 | cullin deneddylation (GO:0010388) | 2.96483262 |
94 | paraxial mesoderm development (GO:0048339) | 2.96151750 |
95 | regulation of sister chromatid cohesion (GO:0007063) | 2.95124620 |
96 | regulation of mitotic spindle organization (GO:0060236) | 2.95046034 |
97 | mitochondrial fusion (GO:0008053) | 2.93734290 |
98 | DNA ligation (GO:0006266) | 2.92810171 |
99 | glucose catabolic process (GO:0006007) | 2.92274538 |
100 | ribosome assembly (GO:0042255) | 2.90736223 |
101 | histone-serine phosphorylation (GO:0035404) | 2.89508855 |
102 | muscle filament sliding (GO:0030049) | 2.87693775 |
103 | actin-myosin filament sliding (GO:0033275) | 2.87693775 |
104 | * carbohydrate catabolic process (GO:0016052) | 2.86731646 |
105 | deoxyribonucleotide biosynthetic process (GO:0009263) | 2.85407459 |
106 | aldehyde catabolic process (GO:0046185) | 2.84605354 |
107 | positive regulation of chromosome segregation (GO:0051984) | 2.84136706 |
108 | establishment of integrated proviral latency (GO:0075713) | 2.81710001 |
109 | carbohydrate phosphorylation (GO:0046835) | 2.81543105 |
110 | positive regulation of mitochondrial membrane permeability (GO:0035794) | 2.81495594 |
111 | vesicle coating (GO:0006901) | 2.81000177 |
112 | NLS-bearing protein import into nucleus (GO:0006607) | 2.80492178 |
113 | ribonucleoprotein complex disassembly (GO:0032988) | 2.80069012 |
114 | mitotic sister chromatid cohesion (GO:0007064) | 2.79751139 |
115 | sequestering of actin monomers (GO:0042989) | 2.79750518 |
116 | oxidative phosphorylation (GO:0006119) | 2.78349957 |
117 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.77988875 |
118 | T cell apoptotic process (GO:0070231) | 2.77683270 |
119 | COPI coating of Golgi vesicle (GO:0048205) | 2.77476043 |
120 | Golgi transport vesicle coating (GO:0048200) | 2.77476043 |
121 | chromosome condensation (GO:0030261) | 2.76886282 |
122 | protein deneddylation (GO:0000338) | 2.74938327 |
123 | regulation of mitochondrial membrane permeability involved in apoptotic process (GO:1902108) | 2.74820373 |
124 | nucleobase-containing small molecule interconversion (GO:0015949) | 2.74024379 |
125 | ribosomal small subunit assembly (GO:0000028) | 2.73399790 |
126 | metaphase plate congression (GO:0051310) | 2.72227283 |
127 | regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510) | 2.70883239 |
128 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 2.70376303 |
129 | negative regulation of DNA repair (GO:0045738) | 2.69585946 |
130 | DNA damage response, detection of DNA damage (GO:0042769) | 2.69535861 |
131 | regulation of oxidative stress-induced neuron death (GO:1903203) | 2.69484884 |
132 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 2.68525283 |
133 | establishment of chromosome localization (GO:0051303) | 2.68405657 |
134 | melanin biosynthetic process (GO:0042438) | 2.68329220 |
135 | regulation of centrosome cycle (GO:0046605) | 2.68254496 |
136 | layer formation in cerebral cortex (GO:0021819) | 2.68065136 |
137 | galactose catabolic process (GO:0019388) | 2.66463070 |
138 | mRNA stabilization (GO:0048255) | 2.66309118 |
139 | RNA stabilization (GO:0043489) | 2.66309118 |
140 | maternal placenta development (GO:0001893) | 2.65984947 |
141 | telomere maintenance via semi-conservative replication (GO:0032201) | 2.65677428 |
142 | * hexose biosynthetic process (GO:0019319) | 2.64215884 |
143 | regulation of centriole replication (GO:0046599) | 2.63546141 |
144 | regulation of transcription from RNA polymerase II promoter involved in heart development (GO:190121 | 2.62559847 |
145 | * monosaccharide biosynthetic process (GO:0046364) | 2.62452157 |
146 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 2.58915784 |
147 | negative regulation of ligase activity (GO:0051352) | 2.58915784 |
148 | spliceosomal snRNP assembly (GO:0000387) | 2.57726141 |
149 | regulation of translational elongation (GO:0006448) | 2.56796238 |
150 | base-excision repair (GO:0006284) | 2.56779816 |
151 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.55694444 |
152 | non-recombinational repair (GO:0000726) | 2.55277735 |
153 | double-strand break repair via nonhomologous end joining (GO:0006303) | 2.55277735 |
154 | COPII vesicle coating (GO:0048208) | 2.53884967 |
155 | nucleoside diphosphate biosynthetic process (GO:0009133) | 2.53858457 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 8.85752908 |
2 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 4.80148248 |
3 | * EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 4.09063668 |
4 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 3.96084049 |
5 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 3.50033595 |
6 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 3.24488790 |
7 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.96109384 |
8 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.84986979 |
9 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 2.70477457 |
10 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 2.61553619 |
11 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.60626403 |
12 | AR_21909140_ChIP-Seq_LNCAP_Human | 2.55698232 |
13 | * MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.51750831 |
14 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 2.42460057 |
15 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 2.21721307 |
16 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 2.20509590 |
17 | * MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.20094639 |
18 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 2.18034972 |
19 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 2.15677418 |
20 | * XRN2_22483619_ChIP-Seq_HELA_Human | 2.14617685 |
21 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.03738440 |
22 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 2.00313923 |
23 | MYC_22102868_ChIP-Seq_BL_Human | 1.99971455 |
24 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.98055697 |
25 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.81337898 |
26 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 1.79712072 |
27 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.78386302 |
28 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.75595287 |
29 | * E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.71755534 |
30 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.69133867 |
31 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.68006183 |
32 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.67642955 |
33 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 1.65080574 |
34 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.64820481 |
35 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.63600336 |
36 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.60888059 |
37 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.59603634 |
38 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.59547826 |
39 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.59243710 |
40 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.57399476 |
41 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.56762517 |
42 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.56106027 |
43 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.56015324 |
44 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.54573542 |
45 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.54323787 |
46 | ZIC3_20872845_ChIP-ChIP_MESCs_Mouse | 1.50509336 |
47 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.48730941 |
48 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.48405217 |
49 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.48210169 |
50 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.48146094 |
51 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.45165720 |
52 | * FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.43429960 |
53 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.41251463 |
54 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 1.40563648 |
55 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.38598832 |
56 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 1.37770930 |
57 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.36059147 |
58 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.35135918 |
59 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 1.34674915 |
60 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.34275322 |
61 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 1.34016330 |
62 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.33798366 |
63 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.29454868 |
64 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.29140332 |
65 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 1.28708906 |
66 | CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.26734809 |
67 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.26273179 |
68 | ATF3_27146783_Chip-Seq_COLON_Human | 1.25223323 |
69 | * CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 1.24833894 |
70 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.23620827 |
71 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.23216178 |
72 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.22159039 |
73 | SALL4_18804426_ChIP-ChIP_MESCs_Mouse | 1.20847109 |
74 | * VDR_23849224_ChIP-Seq_CD4+_Human | 1.20402568 |
75 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 1.18865877 |
76 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.18355619 |
77 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.17945530 |
78 | NANOG_21062744_ChIP-ChIP_HESCs_Human | 1.17028980 |
79 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 1.16106623 |
80 | TCF3_18692474_ChIP-Seq_MEFs_Mouse | 1.15085017 |
81 | TRIM28_19339689_ChIP-ChIP_MESCs_Mouse | 1.14929173 |
82 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 1.14577779 |
83 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.14442715 |
84 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 1.14326575 |
85 | * NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 1.13563803 |
86 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.13532728 |
87 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.12886233 |
88 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.12364253 |
89 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.11013154 |
90 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.10359085 |
91 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.10146163 |
92 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 1.08624029 |
93 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.07633335 |
94 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.07298146 |
95 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 1.06616626 |
96 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.06007462 |
97 | SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 1.05828155 |
98 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.05336678 |
99 | OCT4_18692474_ChIP-Seq_MEFs_Mouse | 1.05198984 |
100 | SOX2_18358816_ChIP-ChIP_MESCs_Mouse | 1.04743594 |
101 | CHD1_26751641_Chip-Seq_LNCaP_Human | 1.02768616 |
102 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.02260960 |
103 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.01904495 |
104 | ATF3_23680149_ChIP-Seq_GBM1-GSC_Human | 1.01811604 |
105 | TCFCP2L1_18555785_ChIP-Seq_MESCs_Mouse | 1.01682114 |
106 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.01093432 |
107 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 0.99833533 |
108 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 0.98724841 |
109 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 0.98675858 |
110 | CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.98118003 |
111 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 0.97175509 |
112 | SOX2_19030024_ChIP-ChIP_MESCs_Mouse | 0.96961626 |
113 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 0.96311962 |
114 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 0.96205574 |
115 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 0.96037696 |
116 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 0.95119035 |
117 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 0.94677737 |
118 | SREBP1_19666523_ChIP-Seq_LIVER_Mouse | 0.94498135 |
119 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 0.92628862 |
120 | TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 0.91193796 |
121 | SOX2_18692474_ChIP-Seq_MEFs_Mouse | 0.88622998 |
122 | EOMES_20176728_ChIP-ChIP_TSCs_Mouse | 0.87520010 |
123 | SOX17_20123909_ChIP-Seq_XEN_Mouse | 0.83444220 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003705_abnormal_hypodermis_morpholog | 3.97279293 |
2 | MP0004084_abnormal_cardiac_muscle | 3.31466591 |
3 | MP0003123_paternal_imprinting | 3.29103211 |
4 | MP0010352_gastrointestinal_tract_polyps | 3.08071028 |
5 | MP0001529_abnormal_vocalization | 2.98565686 |
6 | MP0004957_abnormal_blastocyst_morpholog | 2.92131060 |
7 | MP0010094_abnormal_chromosome_stability | 2.76401627 |
8 | MP0010307_abnormal_tumor_latency | 2.64794933 |
9 | MP0003111_abnormal_nucleus_morphology | 2.55750044 |
10 | MP0003077_abnormal_cell_cycle | 2.50393911 |
11 | MP0001730_embryonic_growth_arrest | 2.47910194 |
12 | MP0005394_taste/olfaction_phenotype | 2.47731730 |
13 | MP0005499_abnormal_olfactory_system | 2.47731730 |
14 | MP0010234_abnormal_vibrissa_follicle | 2.45669141 |
15 | MP0004233_abnormal_muscle_weight | 2.38112694 |
16 | MP0008260_abnormal_autophagy | 2.28109488 |
17 | MP0003567_abnormal_fetal_cardiomyocyte | 2.25917375 |
18 | MP0003221_abnormal_cardiomyocyte_apopto | 2.25898147 |
19 | MP0002877_abnormal_melanocyte_morpholog | 2.09178859 |
20 | MP0010030_abnormal_orbit_morphology | 2.07378270 |
21 | MP0003121_genomic_imprinting | 2.05871803 |
22 | MP0000537_abnormal_urethra_morphology | 2.05246539 |
23 | MP0004197_abnormal_fetal_growth/weight/ | 2.02758418 |
24 | MP0003693_abnormal_embryo_hatching | 2.02652001 |
25 | MP0003566_abnormal_cell_adhesion | 1.98994698 |
26 | MP0000372_irregular_coat_pigmentation | 1.92106611 |
27 | MP0005076_abnormal_cell_differentiation | 1.88657691 |
28 | MP0001697_abnormal_embryo_size | 1.87234233 |
29 | MP0003984_embryonic_growth_retardation | 1.84777266 |
30 | MP0005623_abnormal_meninges_morphology | 1.84674719 |
31 | MP0002088_abnormal_embryonic_growth/wei | 1.83672872 |
32 | MP0000350_abnormal_cell_proliferation | 1.81199243 |
33 | MP0001672_abnormal_embryogenesis/_devel | 1.80032889 |
34 | MP0005380_embryogenesis_phenotype | 1.80032889 |
35 | MP0008058_abnormal_DNA_repair | 1.79749940 |
36 | MP0009697_abnormal_copulation | 1.78205239 |
37 | MP0003122_maternal_imprinting | 1.73232466 |
38 | MP0002084_abnormal_developmental_patter | 1.66333403 |
39 | MP0004036_abnormal_muscle_relaxation | 1.65222953 |
40 | MP0003315_abnormal_perineum_morphology | 1.63610834 |
41 | MP0008932_abnormal_embryonic_tissue | 1.62205260 |
42 | MP0002080_prenatal_lethality | 1.59903598 |
43 | MP0002086_abnormal_extraembryonic_tissu | 1.59838869 |
44 | MP0006035_abnormal_mitochondrial_morpho | 1.57286544 |
45 | MP0000778_abnormal_nervous_system | 1.56493034 |
46 | MP0008775_abnormal_heart_ventricle | 1.56130669 |
47 | MP0003880_abnormal_central_pattern | 1.55207174 |
48 | MP0008007_abnormal_cellular_replicative | 1.54027702 |
49 | MP0004859_abnormal_synaptic_plasticity | 1.53700200 |
50 | MP0004087_abnormal_muscle_fiber | 1.53508931 |
51 | MP0000733_abnormal_muscle_development | 1.51742081 |
52 | MP0010630_abnormal_cardiac_muscle | 1.48786989 |
53 | MP0000749_muscle_degeneration | 1.46271422 |
54 | MP0003806_abnormal_nucleotide_metabolis | 1.45941479 |
55 | MP0000750_abnormal_muscle_regeneration | 1.43690447 |
56 | MP0009053_abnormal_anal_canal | 1.43066618 |
57 | MP0008789_abnormal_olfactory_epithelium | 1.42444866 |
58 | MP0002269_muscular_atrophy | 1.42076056 |
59 | MP0002085_abnormal_embryonic_tissue | 1.41411291 |
60 | MP0003950_abnormal_plasma_membrane | 1.37522989 |
61 | MP0001849_ear_inflammation | 1.36289673 |
62 | MP0002653_abnormal_ependyma_morphology | 1.35597146 |
63 | MP0005023_abnormal_wound_healing | 1.32689375 |
64 | MP0000747_muscle_weakness | 1.32079977 |
65 | MP0000751_myopathy | 1.31015907 |
66 | MP0003329_amyloid_beta_deposits | 1.30901382 |
67 | MP0008438_abnormal_cutaneous_collagen | 1.30148244 |
68 | MP0003186_abnormal_redox_activity | 1.30132498 |
69 | MP0006072_abnormal_retinal_apoptosis | 1.28309072 |
70 | MP0001727_abnormal_embryo_implantation | 1.26116012 |
71 | MP0004272_abnormal_basement_membrane | 1.25811301 |
72 | MP0002972_abnormal_cardiac_muscle | 1.22910560 |
73 | MP0003890_abnormal_embryonic-extraembry | 1.22259752 |
74 | MP0000647_abnormal_sebaceous_gland | 1.18510331 |
75 | MP0004808_abnormal_hematopoietic_stem | 1.17751463 |
76 | MP0005330_cardiomyopathy | 1.17449629 |
77 | MP0001544_abnormal_cardiovascular_syste | 1.15514190 |
78 | MP0005385_cardiovascular_system_phenoty | 1.15514190 |
79 | MP0001299_abnormal_eye_distance/ | 1.14496389 |
80 | MP0001293_anophthalmia | 1.14141934 |
81 | MP0003937_abnormal_limbs/digits/tail_de | 1.12853751 |
82 | MP0004811_abnormal_neuron_physiology | 1.12303828 |
83 | MP0009672_abnormal_birth_weight | 1.05855624 |
84 | MP0001915_intracranial_hemorrhage | 1.05656061 |
85 | MP0001984_abnormal_olfaction | 1.05423786 |
86 | MP0002106_abnormal_muscle_physiology | 1.05133281 |
87 | MP0003283_abnormal_digestive_organ | 1.04678415 |
88 | MP0000371_diluted_coat_color | 1.04358528 |
89 | MP0000358_abnormal_cell_content/ | 1.04209333 |
90 | MP0002233_abnormal_nose_morphology | 1.02620276 |
91 | MP0005248_abnormal_Harderian_gland | 1.02589456 |
92 | MP0002089_abnormal_postnatal_growth/wei | 1.02155465 |
93 | MP0003385_abnormal_body_wall | 0.99348840 |
94 | MP0005408_hypopigmentation | 0.95933669 |
95 | MP0002282_abnormal_trachea_morphology | 0.94929260 |
96 | MP0000266_abnormal_heart_morphology | 0.94845593 |
97 | MP0006138_congestive_heart_failure | 0.94023565 |
98 | MP0008770_decreased_survivor_rate | 0.94002070 |
99 | MP0004484_altered_response_of | 0.93151232 |
100 | MP0002925_abnormal_cardiovascular_devel | 0.90875620 |
101 | MP0002111_abnormal_tail_morphology | 0.90528356 |
102 | MP0004215_abnormal_myocardial_fiber | 0.89636650 |
103 | MP0005171_absent_coat_pigmentation | 0.89553750 |
104 | MP0002751_abnormal_autonomic_nervous | 0.88875583 |
105 | MP0003861_abnormal_nervous_system | 0.88836767 |
106 | MP0003115_abnormal_respiratory_system | 0.88691870 |
107 | MP0002184_abnormal_innervation | 0.88047408 |
108 | MP0004270_analgesia | 0.87050712 |
109 | MP0005620_abnormal_muscle_contractility | 0.86390876 |
110 | MP0000759_abnormal_skeletal_muscle | 0.86236167 |
111 | MP0002090_abnormal_vision | 0.85867176 |
112 | MP0008057_abnormal_DNA_replication | 0.85817241 |
113 | MP0000428_abnormal_craniofacial_morphol | 0.85033407 |
114 | MP0004858_abnormal_nervous_system | 0.85004712 |
115 | MP0000313_abnormal_cell_death | 0.84898037 |
116 | MP0002092_abnormal_eye_morphology | 0.84314945 |
117 | MP0003786_premature_aging | 0.83877927 |
118 | MP0002938_white_spotting | 0.83280397 |
119 | MP0002697_abnormal_eye_size | 0.83141122 |
120 | MP0003646_muscle_fatigue | 0.83082443 |
121 | MP0001286_abnormal_eye_development | 0.82477386 |
122 | MP0006292_abnormal_olfactory_placode | 0.82334670 |
123 | MP0003942_abnormal_urinary_system | 0.82257805 |
124 | MP0003119_abnormal_digestive_system | 0.82098685 |
125 | MP0003091_abnormal_cell_migration | 0.81032804 |
126 | MP0005197_abnormal_uvea_morphology | 0.80770473 |
127 | MP0000003_abnormal_adipose_tissue | 0.79858591 |
128 | MP0005257_abnormal_intraocular_pressure | 0.79685617 |
129 | MP0005384_cellular_phenotype | 0.78831127 |
130 | MP0005584_abnormal_enzyme/coenzyme_acti | 0.78629308 |
131 | MP0000534_abnormal_ureter_morphology | 0.78461267 |
132 | MP0000579_abnormal_nail_morphology | 0.78203085 |
133 | MP0006054_spinal_hemorrhage | 0.78114801 |
134 | MP0005501_abnormal_skin_physiology | 0.77332158 |
135 | MP0001340_abnormal_eyelid_morphology | 0.75046384 |
136 | MP0004264_abnormal_extraembryonic_tissu | 0.74840462 |
137 | MP0005621_abnormal_cell_physiology | 0.73879819 |
138 | MP0002009_preneoplasia | 0.73246775 |
139 | MP0005369_muscle_phenotype | 0.73216605 |
140 | MP0003172_abnormal_lysosome_physiology | 0.72967543 |
141 | MP0009703_decreased_birth_body | 0.72756025 |
142 | MP0002152_abnormal_brain_morphology | 0.71560441 |
143 | MP0002332_abnormal_exercise_endurance | 0.69544581 |
144 | MP0002019_abnormal_tumor_incidence | 0.68786907 |
145 | MP0005187_abnormal_penis_morphology | 0.67017065 |
146 | MP0000490_abnormal_crypts_of | 0.66039605 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Abnormality of glycolysis (HP:0004366) | 4.54052547 |
2 | Increased serum pyruvate (HP:0003542) | 4.54052547 |
3 | Abnormal gallbladder physiology (HP:0012438) | 4.46613477 |
4 | Cholecystitis (HP:0001082) | 4.46613477 |
5 | Ependymoma (HP:0002888) | 3.70176568 |
6 | Abnormal gallbladder morphology (HP:0012437) | 3.53776244 |
7 | Subacute progressive viral hepatitis (HP:0006572) | 3.47776867 |
8 | Cutaneous melanoma (HP:0012056) | 3.41269528 |
9 | * Exercise-induced muscle cramps (HP:0003710) | 3.38146669 |
10 | Adenoma sebaceum (HP:0009720) | 3.30582212 |
11 | Angiofibromas (HP:0010615) | 3.30582212 |
12 | Astrocytoma (HP:0009592) | 3.10598882 |
13 | Abnormality of the astrocytes (HP:0100707) | 3.10598882 |
14 | Spastic diplegia (HP:0001264) | 3.05814240 |
15 | Microvesicular hepatic steatosis (HP:0001414) | 3.00224761 |
16 | Postnatal microcephaly (HP:0005484) | 2.93751697 |
17 | Hypoplastic pelvis (HP:0008839) | 2.76063671 |
18 | Deviation of the thumb (HP:0009603) | 2.74001756 |
19 | Colon cancer (HP:0003003) | 2.72606805 |
20 | Selective tooth agenesis (HP:0001592) | 2.72188748 |
21 | Abnormality of the gallbladder (HP:0005264) | 2.70669211 |
22 | Increased density of long bones (HP:0006392) | 2.68204205 |
23 | Conjunctival hamartoma (HP:0100780) | 2.67833399 |
24 | Agnosia (HP:0010524) | 2.65956716 |
25 | Abnormality of the calcaneus (HP:0008364) | 2.65938173 |
26 | Premature rupture of membranes (HP:0001788) | 2.64472972 |
27 | Metaphyseal cupping (HP:0003021) | 2.64298323 |
28 | Missing ribs (HP:0000921) | 2.50072152 |
29 | Decreased number of large peripheral myelinated nerve fibers (HP:0003387) | 2.48325618 |
30 | Upper limb muscle weakness (HP:0003484) | 2.48176699 |
31 | Hypoplasia of the capital femoral epiphysis (HP:0003090) | 2.45075926 |
32 | Atrophy/Degeneration involving motor neurons (HP:0007373) | 2.43736520 |
33 | Proximal placement of thumb (HP:0009623) | 2.41669020 |
34 | Cervical subluxation (HP:0003308) | 2.40757335 |
35 | Neoplasm of the rectum (HP:0100743) | 2.31415588 |
36 | Resting tremor (HP:0002322) | 2.31405798 |
37 | Ovarian neoplasm (HP:0100615) | 2.31400492 |
38 | Centrally nucleated skeletal muscle fibers (HP:0003687) | 2.29994287 |
39 | Aplasia/Hypoplasia of the vertebrae (HP:0008515) | 2.29978854 |
40 | Vertebral hypoplasia (HP:0008417) | 2.29978854 |
41 | Intestinal polyposis (HP:0200008) | 2.26663027 |
42 | Hand muscle atrophy (HP:0009130) | 2.26551578 |
43 | Biliary tract neoplasm (HP:0100574) | 2.26090356 |
44 | Fibroma (HP:0010614) | 2.25737419 |
45 | Pelvic girdle muscle weakness (HP:0003749) | 2.25224274 |
46 | Ulnar deviation of the wrist (HP:0003049) | 2.25008481 |
47 | Freckling (HP:0001480) | 2.24221138 |
48 | Absent epiphyses (HP:0010577) | 2.22629135 |
49 | Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003) | 2.22629135 |
50 | Protrusio acetabuli (HP:0003179) | 2.22057757 |
51 | Upper limb amyotrophy (HP:0009129) | 2.21904586 |
52 | Distal upper limb amyotrophy (HP:0007149) | 2.21904586 |
53 | Insomnia (HP:0100785) | 2.21438885 |
54 | Termporal pattern (HP:0011008) | 2.20343549 |
55 | Insidious onset (HP:0003587) | 2.20343549 |
56 | High anterior hairline (HP:0009890) | 2.20295867 |
57 | * Myoglobinuria (HP:0002913) | 2.19083572 |
58 | * Reticulocytosis (HP:0001923) | 2.19031652 |
59 | Intestinal polyp (HP:0005266) | 2.19000095 |
60 | Fibrous tissue neoplasm (HP:0012316) | 2.17952024 |
61 | Multiple enchondromatosis (HP:0005701) | 2.17836280 |
62 | Shoulder girdle muscle weakness (HP:0003547) | 2.17086724 |
63 | Scapular winging (HP:0003691) | 2.14846323 |
64 | Abnormal neuron morphology (HP:0012757) | 2.08441676 |
65 | Abnormality of the motor neurons (HP:0002450) | 2.08441676 |
66 | Increased nuchal translucency (HP:0010880) | 2.08372276 |
67 | * Rhabdomyolysis (HP:0003201) | 2.08135682 |
68 | Hypopigmentation of the fundus (HP:0007894) | 2.07871837 |
69 | Rhabdomyosarcoma (HP:0002859) | 2.06585626 |
70 | Gout (HP:0001997) | 2.06479227 |
71 | Abnormality of dentin (HP:0010299) | 2.05975446 |
72 | Breech presentation (HP:0001623) | 2.05220665 |
73 | Abnormality of the labia minora (HP:0012880) | 2.04253699 |
74 | Glioma (HP:0009733) | 2.02260213 |
75 | Hyperglycinemia (HP:0002154) | 2.01562637 |
76 | Hamartoma of the eye (HP:0010568) | 2.00390265 |
77 | Type I transferrin isoform profile (HP:0003642) | 1.99708804 |
78 | Limb-girdle muscle atrophy (HP:0003797) | 1.99258029 |
79 | Renal duplication (HP:0000075) | 1.97644781 |
80 | Type 1 muscle fiber predominance (HP:0003803) | 1.97191781 |
81 | Uterine neoplasm (HP:0010784) | 1.96222894 |
82 | Abnormality of the hip-girdle musculature (HP:0001445) | 1.94316493 |
83 | Abnormality of the musculature of the pelvis (HP:0001469) | 1.94316493 |
84 | Hammertoe (HP:0001765) | 1.92614320 |
85 | Entropion (HP:0000621) | 1.89682593 |
86 | Long palpebral fissure (HP:0000637) | 1.88794136 |
87 | Muscle stiffness (HP:0003552) | 1.87956604 |
88 | Neoplasm of the adrenal gland (HP:0100631) | 1.87368842 |
89 | Aplasia/Hypoplasia of the breasts (HP:0010311) | 1.87201134 |
90 | Dysmetric saccades (HP:0000641) | 1.87061820 |
91 | Overlapping toe (HP:0001845) | 1.86695816 |
92 | Increased connective tissue (HP:0009025) | 1.86243645 |
93 | Hyperacusis (HP:0010780) | 1.85100490 |
94 | Ankle contracture (HP:0006466) | 1.84876353 |
95 | Back pain (HP:0003418) | 1.84824633 |
96 | Peripheral hypomyelination (HP:0007182) | 1.83966688 |
97 | Generalized hypotonia (HP:0001290) | 1.83563353 |
98 | Neoplasm of the small intestine (HP:0100833) | 1.82671167 |
99 | Abnormality of the lower motor neuron (HP:0002366) | 1.82651874 |
100 | Melanoma (HP:0002861) | 1.81977711 |
101 | Cortical dysplasia (HP:0002539) | 1.81710652 |
102 | Ragged-red muscle fibers (HP:0003200) | 1.80305365 |
103 | Reduced antithrombin III activity (HP:0001976) | 1.80045906 |
104 | * Abnormality of reticulocytes (HP:0004312) | 1.79621180 |
105 | Exostoses (HP:0100777) | 1.78162359 |
106 | Posterior subcapsular cataract (HP:0007787) | 1.77040716 |
107 | Congenital primary aphakia (HP:0007707) | 1.76631024 |
108 | Abnormal mitochondria in muscle tissue (HP:0008316) | 1.76447923 |
109 | High pitched voice (HP:0001620) | 1.76045709 |
110 | Pseudobulbar signs (HP:0002200) | 1.75309436 |
111 | Broad foot (HP:0001769) | 1.74339954 |
112 | Neoplasm of the colon (HP:0100273) | 1.74025877 |
113 | Exercise-induced myalgia (HP:0003738) | 1.73839881 |
114 | Short humerus (HP:0005792) | 1.73830534 |
115 | Pheochromocytoma (HP:0002666) | 1.73751995 |
116 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 1.72469279 |
117 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 1.72469279 |
118 | Medulloblastoma (HP:0002885) | 1.72405517 |
119 | Orthostatic hypotension (HP:0001278) | 1.72110249 |
120 | Broad alveolar ridges (HP:0000187) | 1.70912414 |
121 | Breast aplasia (HP:0100783) | 1.70879240 |
122 | Nephrogenic diabetes insipidus (HP:0009806) | 1.70351134 |
123 | Delayed puberty (HP:0000823) | 1.69585807 |
124 | Radial bowing (HP:0002986) | 1.68315373 |
125 | CNS hypomyelination (HP:0003429) | 1.68174072 |
126 | Malignant gastrointestinal tract tumors (HP:0006749) | 1.67733565 |
127 | Gastrointestinal carcinoma (HP:0002672) | 1.67733565 |
128 | Gait imbalance (HP:0002141) | 1.67608303 |
129 | Abnormality of the left ventricular outflow tract (HP:0011103) | 1.66265625 |
130 | Subaortic stenosis (HP:0001682) | 1.66265625 |
131 | * Exercise intolerance (HP:0003546) | 1.65615098 |
132 | Broad thumb (HP:0011304) | 1.65476560 |
133 | EMG: myopathic abnormalities (HP:0003458) | 1.65320426 |
134 | Cholelithiasis (HP:0001081) | 1.65009477 |
135 | Basal cell carcinoma (HP:0002671) | 1.64230438 |
136 | Cafe-au-lait spot (HP:0000957) | 1.63722222 |
137 | Trigonocephaly (HP:0000243) | 1.63152412 |
138 | Degeneration of anterior horn cells (HP:0002398) | 1.63050182 |
139 | Abnormality of the anterior horn cell (HP:0006802) | 1.63050182 |
140 | Bilateral sensorineural hearing impairment (HP:0008619) | 1.62743638 |
141 | Micronodular cirrhosis (HP:0001413) | 1.60837434 |
142 | Microglossia (HP:0000171) | 1.60832289 |
143 | Aplasia/hypoplasia of the humerus (HP:0006507) | 1.60605391 |
144 | Abnormality of pain sensation (HP:0010832) | 1.60508486 |
145 | Impaired pain sensation (HP:0007328) | 1.60508486 |
146 | Glossoptosis (HP:0000162) | 1.59813180 |
147 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 1.59680477 |
148 | Abnormal protein N-linked glycosylation (HP:0012347) | 1.59680477 |
149 | Abnormal protein glycosylation (HP:0012346) | 1.59680477 |
150 | Abnormal glycosylation (HP:0012345) | 1.59680477 |
151 | Increased serum lactate (HP:0002151) | 1.58409597 |
152 | Ulnar bowing (HP:0003031) | 1.58408371 |
153 | Tetraparesis (HP:0002273) | 1.57707972 |
154 | Cerebral aneurysm (HP:0004944) | 1.57562463 |
155 | Primitive neuroectodermal tumor (HP:0030065) | 1.57427739 |
156 | Neuroblastic tumors (HP:0004376) | 1.57427739 |
157 | Peripheral primitive neuroectodermal neoplasm (HP:0030067) | 1.57427739 |
158 | Dental crowding (HP:0000678) | 1.56762577 |
159 | Irregular epiphyses (HP:0010582) | 1.55498018 |
160 | Impaired proprioception (HP:0010831) | 1.54576886 |
161 | Pterygium (HP:0001059) | 1.54474932 |
162 | Hepatic necrosis (HP:0002605) | 1.54093240 |
163 | Decreased testicular size (HP:0008734) | 1.53505301 |
164 | Cerebral edema (HP:0002181) | 1.50948402 |
165 | Abnormality of long-chain fatty-acid metabolism (HP:0010964) | 1.50110145 |
166 | Facial cleft (HP:0002006) | 1.49511666 |
167 | Prominent metopic ridge (HP:0005487) | 1.49242081 |
168 | Neuroendocrine neoplasm (HP:0100634) | 1.48783879 |
169 | Hepatocellular necrosis (HP:0001404) | 1.48690840 |
170 | Hyperammonemia (HP:0001987) | 1.48470427 |
171 | Pointed chin (HP:0000307) | 1.47801144 |
172 | Poikiloderma (HP:0001029) | 1.47623399 |
173 | Erectile abnormalities (HP:0100639) | 1.47333027 |
Rank | Gene Set | Z-score |
---|---|---|
1 | PKN2 | 6.47593301 |
2 | NEK1 | 4.40939082 |
3 | BCKDK | 3.45621723 |
4 | SRPK1 | 3.43296402 |
5 | BCR | 3.09493527 |
6 | CDC7 | 2.97751839 |
7 | EEF2K | 2.95401559 |
8 | TRIB3 | 2.95007413 |
9 | FLT3 | 2.51716045 |
10 | WEE1 | 2.46568418 |
11 | TRIM28 | 2.39599686 |
12 | SCYL2 | 2.27512600 |
13 | TTN | 2.18166480 |
14 | CDK19 | 2.16869974 |
15 | TSSK6 | 2.07382489 |
16 | NEK2 | 2.04417567 |
17 | PASK | 1.77076943 |
18 | SIK3 | 1.70228193 |
19 | VRK2 | 1.67329213 |
20 | FGFR1 | 1.64058994 |
21 | OBSCN | 1.63986492 |
22 | LRRK2 | 1.62876369 |
23 | BMX | 1.62182945 |
24 | MAP2K7 | 1.58475701 |
25 | TTK | 1.53319713 |
26 | RPS6KB2 | 1.48796422 |
27 | PAK4 | 1.44823574 |
28 | BUB1 | 1.42277306 |
29 | CSNK1G3 | 1.39933737 |
30 | MAP3K8 | 1.38130117 |
31 | CSNK1A1L | 1.38085085 |
32 | ERBB3 | 1.38044763 |
33 | ALK | 1.36361748 |
34 | PLK3 | 1.33680029 |
35 | CDK12 | 1.32536879 |
36 | TESK1 | 1.30020428 |
37 | MAP4K2 | 1.29163881 |
38 | KSR2 | 1.26476577 |
39 | MAP3K10 | 1.24100121 |
40 | LIMK1 | 1.23022792 |
41 | EPHA2 | 1.19701817 |
42 | LMTK2 | 1.18799947 |
43 | CSNK1G2 | 1.16520757 |
44 | CDK4 | 1.11104664 |
45 | BRSK2 | 1.06986509 |
46 | STK10 | 1.06745377 |
47 | VRK1 | 1.06480647 |
48 | PTK6 | 1.06100174 |
49 | TGFBR1 | 1.04327037 |
50 | CDK6 | 1.03681820 |
51 | DYRK3 | 1.03176909 |
52 | PDK4 | 1.02816984 |
53 | PDK3 | 1.02816984 |
54 | MST1R | 0.97164150 |
55 | NME2 | 0.97117571 |
56 | ICK | 0.96867128 |
57 | MET | 0.96297933 |
58 | ILK | 0.94843002 |
59 | EIF2AK1 | 0.94210683 |
60 | KSR1 | 0.94160980 |
61 | PLK1 | 0.93956233 |
62 | AURKB | 0.93489019 |
63 | MAP2K3 | 0.91136035 |
64 | MAP3K9 | 0.87797390 |
65 | NTRK1 | 0.85029161 |
66 | CSNK1G1 | 0.84251460 |
67 | NEK9 | 0.84228960 |
68 | PAK2 | 0.83960290 |
69 | PIM2 | 0.83771068 |
70 | ATR | 0.82857942 |
71 | PLK2 | 0.82008035 |
72 | STK3 | 0.80355124 |
73 | MKNK1 | 0.80206891 |
74 | PDGFRA | 0.79008967 |
75 | AKT2 | 0.77545880 |
76 | BRSK1 | 0.77500939 |
77 | MAP3K4 | 0.74388977 |
78 | CHEK1 | 0.73795823 |
79 | MARK1 | 0.72294553 |
80 | STK38L | 0.71781089 |
81 | DYRK2 | 0.70605252 |
82 | TESK2 | 0.70021890 |
83 | LATS2 | 0.67835783 |
84 | SMG1 | 0.65385269 |
85 | EPHA3 | 0.64491617 |
86 | BRAF | 0.63518133 |
87 | DYRK1B | 0.62854815 |
88 | CCNB1 | 0.62381638 |
89 | PAK1 | 0.61914975 |
90 | MINK1 | 0.61839554 |
91 | DAPK1 | 0.61788267 |
92 | RPS6KA4 | 0.61715875 |
93 | RIPK1 | 0.61221697 |
94 | CDK8 | 0.61043696 |
95 | STK16 | 0.60789955 |
96 | STK4 | 0.60535592 |
97 | DDR2 | 0.60476095 |
98 | RET | 0.60318605 |
99 | FGFR4 | 0.59656243 |
100 | LATS1 | 0.58932039 |
101 | RPS6KA5 | 0.58036569 |
102 | DAPK3 | 0.56767815 |
103 | EPHA4 | 0.56255122 |
104 | EPHB1 | 0.55601562 |
105 | MOS | 0.54804942 |
106 | RAF1 | 0.54480094 |
107 | SIK2 | 0.53505942 |
108 | CDK7 | 0.52438327 |
109 | STK24 | 0.52178844 |
110 | AURKA | 0.51749047 |
111 | EPHB2 | 0.50777136 |
112 | PAK6 | 0.50190880 |
113 | ROCK2 | 0.48763778 |
114 | CDK2 | 0.48514603 |
115 | CDK14 | 0.47407080 |
116 | ARAF | 0.46515635 |
117 | BRD4 | 0.46117781 |
118 | MELK | 0.45899729 |
119 | CDK15 | 0.44988191 |
120 | MTOR | 0.44600033 |
121 | GRK6 | 0.44513475 |
122 | TRPM7 | 0.43637088 |
123 | CDK18 | 0.43305768 |
124 | ATM | 0.42734705 |
125 | MARK3 | 0.42393623 |
126 | FER | 0.41262605 |
127 | NME1 | 0.40178897 |
128 | PBK | 0.39743685 |
129 | UHMK1 | 0.39669451 |
130 | CHEK2 | 0.39208762 |
131 | MAP3K5 | 0.38889225 |
132 | CDK11A | 0.36131500 |
133 | PTK2 | 0.35739916 |
134 | MAPKAPK5 | 0.35724362 |
135 | CDK9 | 0.35721764 |
136 | PDK2 | 0.35604436 |
137 | PIM1 | 0.35424584 |
138 | CDK1 | 0.33610281 |
139 | CSNK2A2 | 0.30035073 |
140 | EGFR | 0.29944708 |
141 | CSNK1D | 0.29527306 |
142 | ERBB4 | 0.27908871 |
143 | EIF2AK3 | 0.27569615 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 3.81155522 |
2 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 3.25454484 |
3 | DNA replication_Homo sapiens_hsa03030 | 3.12875331 |
4 | * Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 3.12083890 |
5 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 3.06317736 |
6 | * Biosynthesis of amino acids_Homo sapiens_hsa01230 | 3.05953041 |
7 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.90201253 |
8 | * Carbon metabolism_Homo sapiens_hsa01200 | 2.76231225 |
9 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 2.68260087 |
10 | Mismatch repair_Homo sapiens_hsa03430 | 2.63424676 |
11 | Steroid biosynthesis_Homo sapiens_hsa00100 | 2.50915708 |
12 | RNA transport_Homo sapiens_hsa03013 | 2.33174611 |
13 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 2.21735158 |
14 | Cell cycle_Homo sapiens_hsa04110 | 2.02042932 |
15 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 1.99602957 |
16 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 1.95046012 |
17 | Protein export_Homo sapiens_hsa03060 | 1.92992213 |
18 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.92974128 |
19 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 1.80992630 |
20 | * HIF-1 signaling pathway_Homo sapiens_hsa04066 | 1.80963702 |
21 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 1.79828458 |
22 | Proteasome_Homo sapiens_hsa03050 | 1.74149161 |
23 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.73655230 |
24 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.72220811 |
25 | Galactose metabolism_Homo sapiens_hsa00052 | 1.66379041 |
26 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.66304836 |
27 | Spliceosome_Homo sapiens_hsa03040 | 1.63818551 |
28 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.59846883 |
29 | Base excision repair_Homo sapiens_hsa03410 | 1.39308816 |
30 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.36673580 |
31 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.27350184 |
32 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.22303544 |
33 | Ribosome_Homo sapiens_hsa03010 | 1.20842592 |
34 | Bladder cancer_Homo sapiens_hsa05219 | 1.17041147 |
35 | Viral carcinogenesis_Homo sapiens_hsa05203 | 1.14006440 |
36 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.11960179 |
37 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 1.10309887 |
38 | RNA degradation_Homo sapiens_hsa03018 | 1.09969439 |
39 | mTOR signaling pathway_Homo sapiens_hsa04150 | 1.07890976 |
40 | Legionellosis_Homo sapiens_hsa05134 | 1.02295692 |
41 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 1.02118708 |
42 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 1.02095484 |
43 | Oocyte meiosis_Homo sapiens_hsa04114 | 1.02061027 |
44 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.01082501 |
45 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.98857131 |
46 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.96558406 |
47 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.95418560 |
48 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.94043172 |
49 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.92827903 |
50 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.92598545 |
51 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.91560753 |
52 | Thyroid cancer_Homo sapiens_hsa05216 | 0.91380788 |
53 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.89559991 |
54 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.88140781 |
55 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.88095823 |
56 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.86258587 |
57 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.84982104 |
58 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.83453591 |
59 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.83383404 |
60 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.83058057 |
61 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.83000026 |
62 | Adherens junction_Homo sapiens_hsa04520 | 0.82069804 |
63 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.81626978 |
64 | Focal adhesion_Homo sapiens_hsa04510 | 0.77202462 |
65 | Viral myocarditis_Homo sapiens_hsa05416 | 0.76058412 |
66 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.75718496 |
67 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.74998853 |
68 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.74828714 |
69 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.71844642 |
70 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.70977726 |
71 | HTLV-I infection_Homo sapiens_hsa05166 | 0.69056954 |
72 | Parkinsons disease_Homo sapiens_hsa05012 | 0.69035276 |
73 | Tight junction_Homo sapiens_hsa04530 | 0.67776456 |
74 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.66741389 |
75 | Colorectal cancer_Homo sapiens_hsa05210 | 0.66366329 |
76 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.64888014 |
77 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.64667750 |
78 | Homologous recombination_Homo sapiens_hsa03440 | 0.64176990 |
79 | Melanoma_Homo sapiens_hsa05218 | 0.63646454 |
80 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.63640688 |
81 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.62711272 |
82 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.61600764 |
83 | Purine metabolism_Homo sapiens_hsa00230 | 0.61459552 |
84 | Glioma_Homo sapiens_hsa05214 | 0.60386658 |
85 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.58471076 |
86 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.58136213 |
87 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.57689574 |
88 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.56990870 |
89 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.56870466 |
90 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.56253157 |
91 | Alzheimers disease_Homo sapiens_hsa05010 | 0.55914810 |
92 | Sulfur relay system_Homo sapiens_hsa04122 | 0.54053287 |
93 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.53240276 |
94 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.51072002 |
95 | * Metabolic pathways_Homo sapiens_hsa01100 | 0.50368302 |
96 | RNA polymerase_Homo sapiens_hsa03020 | 0.48264633 |
97 | Endometrial cancer_Homo sapiens_hsa05213 | 0.46672086 |
98 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.45681078 |
99 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.44885149 |
100 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.44693009 |
101 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.41579343 |
102 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.41171763 |
103 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.40970413 |
104 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.40464121 |
105 | Shigellosis_Homo sapiens_hsa05131 | 0.40439510 |
106 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.39653217 |
107 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.39305965 |
108 | Huntingtons disease_Homo sapiens_hsa05016 | 0.38803993 |
109 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.38563107 |
110 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.38188524 |
111 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.37963721 |
112 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.37123042 |
113 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.37002011 |
114 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.36799194 |
115 | Alcoholism_Homo sapiens_hsa05034 | 0.35328716 |
116 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.33116016 |
117 | Hepatitis B_Homo sapiens_hsa05161 | 0.33022108 |
118 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.32316149 |
119 | Apoptosis_Homo sapiens_hsa04210 | 0.32290485 |
120 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.32069173 |
121 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.31357242 |
122 | Axon guidance_Homo sapiens_hsa04360 | 0.31134591 |
123 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.31035935 |
124 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.29437941 |
125 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.29207566 |
126 | Phagosome_Homo sapiens_hsa04145 | 0.27888204 |
127 | Salmonella infection_Homo sapiens_hsa05132 | 0.27177614 |
128 | Peroxisome_Homo sapiens_hsa04146 | 0.26675280 |
129 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.24952000 |
130 | Basal transcription factors_Homo sapiens_hsa03022 | 0.24679557 |
131 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.20836761 |
132 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.19738810 |
133 | Lysine degradation_Homo sapiens_hsa00310 | 0.18312424 |