

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | regulation of isotype switching to IgG isotypes (GO:0048302) | 8.17706697 |
| 2 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 7.89670804 |
| 3 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 7.12407819 |
| 4 | regulation of immunoglobulin secretion (GO:0051023) | 6.78348896 |
| 5 | positive regulation of isotype switching (GO:0045830) | 5.95365001 |
| 6 | regulation of regulatory T cell differentiation (GO:0045589) | 5.78796150 |
| 7 | positive regulation of DNA recombination (GO:0045911) | 5.53909832 |
| 8 | termination of RNA polymerase I transcription (GO:0006363) | 4.92243057 |
| 9 | proteasome assembly (GO:0043248) | 4.90364745 |
| 10 | regulation of podosome assembly (GO:0071801) | 4.88128499 |
| 11 | positive regulation of immunoglobulin production (GO:0002639) | 4.88061880 |
| 12 | negative regulation of B cell apoptotic process (GO:0002903) | 4.85542994 |
| 13 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.26791332 |
| 14 | regulation of chronic inflammatory response (GO:0002676) | 4.21146982 |
| 15 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 4.08034093 |
| 16 | termination of RNA polymerase III transcription (GO:0006386) | 4.08034093 |
| 17 | regulation of isotype switching (GO:0045191) | 4.07640619 |
| 18 | transcription elongation from RNA polymerase I promoter (GO:0006362) | 4.04526142 |
| 19 | T-helper cell differentiation (GO:0042093) | 4.02515889 |
| 20 | CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294) | 4.02515889 |
| 21 | transcription from RNA polymerase I promoter (GO:0006360) | 3.99222836 |
| 22 | peptidyl-histidine modification (GO:0018202) | 3.96469684 |
| 23 | positive regulation of interleukin-17 production (GO:0032740) | 3.94836516 |
| 24 | positive regulation of B cell proliferation (GO:0030890) | 3.83761584 |
| 25 | regulation of RIG-I signaling pathway (GO:0039535) | 3.81874495 |
| 26 | positive regulation of immunoglobulin mediated immune response (GO:0002891) | 3.71454766 |
| 27 | positive regulation of B cell mediated immunity (GO:0002714) | 3.71454766 |
| 28 | transcription initiation from RNA polymerase I promoter (GO:0006361) | 3.70016498 |
| 29 | ribosome biogenesis (GO:0042254) | 3.67599784 |
| 30 | regulation of immunoglobulin production (GO:0002637) | 3.65463837 |
| 31 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.59638591 |
| 32 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.59297944 |
| 33 | positive regulation of granulocyte differentiation (GO:0030854) | 3.50371653 |
| 34 | alpha-beta T cell differentiation involved in immune response (GO:0002293) | 3.49608840 |
| 35 | alpha-beta T cell activation involved in immune response (GO:0002287) | 3.49608840 |
| 36 | T cell differentiation involved in immune response (GO:0002292) | 3.49608840 |
| 37 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.46663419 |
| 38 | regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway (GO:0039531) | 3.43074177 |
| 39 | DNA damage response, detection of DNA damage (GO:0042769) | 3.42447657 |
| 40 | CD4-positive, alpha-beta T cell differentiation (GO:0043367) | 3.38270508 |
| 41 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 3.38082464 |
| 42 | CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369) | 3.36043565 |
| 43 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.36025799 |
| 44 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.36025799 |
| 45 | ATP synthesis coupled proton transport (GO:0015986) | 3.34789082 |
| 46 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.34789082 |
| 47 | iron ion import (GO:0097286) | 3.33629389 |
| 48 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.30362103 |
| 49 | negative regulation of ligase activity (GO:0051352) | 3.29384800 |
| 50 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.29384800 |
| 51 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.21020892 |
| 52 | protein K6-linked ubiquitination (GO:0085020) | 3.19682837 |
| 53 | rRNA modification (GO:0000154) | 3.19130689 |
| 54 | maturation of SSU-rRNA (GO:0030490) | 3.19083859 |
| 55 | polarized epithelial cell differentiation (GO:0030859) | 3.18006381 |
| 56 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.17433097 |
| 57 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.17433097 |
| 58 | NADH dehydrogenase complex assembly (GO:0010257) | 3.17433097 |
| 59 | kynurenine metabolic process (GO:0070189) | 3.14782881 |
| 60 | CD4-positive, alpha-beta T cell activation (GO:0035710) | 3.10747781 |
| 61 | protein complex biogenesis (GO:0070271) | 3.09510749 |
| 62 | DNA double-strand break processing (GO:0000729) | 3.09383059 |
| 63 | GTP biosynthetic process (GO:0006183) | 3.06769234 |
| 64 | negative regulation of heart rate (GO:0010459) | 3.06336365 |
| 65 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.05752187 |
| 66 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.05664657 |
| 67 | positive regulation of activated T cell proliferation (GO:0042104) | 3.05024138 |
| 68 | negative regulation of T-helper cell differentiation (GO:0045623) | 3.01000398 |
| 69 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 3.01000398 |
| 70 | tryptophan metabolic process (GO:0006568) | 3.00996678 |
| 71 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.99836618 |
| 72 | ribonucleoprotein complex biogenesis (GO:0022613) | 2.98241198 |
| 73 | hormone catabolic process (GO:0042447) | 2.98236766 |
| 74 | rRNA processing (GO:0006364) | 2.98208834 |
| 75 | alpha-beta T cell differentiation (GO:0046632) | 2.94327256 |
| 76 | folic acid-containing compound biosynthetic process (GO:0009396) | 2.93973568 |
| 77 | cullin deneddylation (GO:0010388) | 2.93895482 |
| 78 | cellular component biogenesis (GO:0044085) | 2.93705805 |
| 79 | protein targeting to mitochondrion (GO:0006626) | 2.93379691 |
| 80 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.93176692 |
| 81 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 2.93176692 |
| 82 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.93176692 |
| 83 | pseudouridine synthesis (GO:0001522) | 2.92997724 |
| 84 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 2.92287411 |
| 85 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.91535249 |
| 86 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 2.91535249 |
| 87 | negative regulation of heart contraction (GO:0045822) | 2.90222130 |
| 88 | rRNA metabolic process (GO:0016072) | 2.90118085 |
| 89 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 2.88774723 |
| 90 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 2.87747400 |
| 91 | chaperone-mediated protein transport (GO:0072321) | 2.87632178 |
| 92 | behavioral response to nicotine (GO:0035095) | 2.87275782 |
| 93 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 2.83100269 |
| 94 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 2.83100269 |
| 95 | positive regulation of hormone biosynthetic process (GO:0046886) | 2.80416727 |
| 96 | positive regulation of tyrosine phosphorylation of STAT protein (GO:0042531) | 2.79637568 |
| 97 | DNA deamination (GO:0045006) | 2.79246317 |
| 98 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 2.78946346 |
| 99 | tRNA processing (GO:0008033) | 2.77942496 |
| 100 | negative regulation of acute inflammatory response (GO:0002674) | 2.77503764 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 7.24408696 |
| 2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 5.65096680 |
| 3 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.55555808 |
| 4 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 4.05085676 |
| 5 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.82190104 |
| 6 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 3.48253092 |
| 7 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.32198404 |
| 8 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.14642776 |
| 9 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 3.14219041 |
| 10 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 3.08560391 |
| 11 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.95595792 |
| 12 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.79745759 |
| 13 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.78596841 |
| 14 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.62445654 |
| 15 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 2.56714422 |
| 16 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.43508055 |
| 17 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 2.30281169 |
| 18 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.24569044 |
| 19 | DCP1A_22483619_ChIP-Seq_HELA_Human | 2.20202841 |
| 20 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.13713235 |
| 21 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.08187541 |
| 22 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.99693651 |
| 23 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.99281911 |
| 24 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.77766824 |
| 25 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.77335030 |
| 26 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.76314410 |
| 27 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.74740889 |
| 28 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.74180581 |
| 29 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.66963323 |
| 30 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.66504392 |
| 31 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.65708179 |
| 32 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.65654874 |
| 33 | LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.65127746 |
| 34 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.63587142 |
| 35 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.61841819 |
| 36 | VDR_22108803_ChIP-Seq_LS180_Human | 1.58917956 |
| 37 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.58641559 |
| 38 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.54053146 |
| 39 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.52517154 |
| 40 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.49193881 |
| 41 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.44346196 |
| 42 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.41253929 |
| 43 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.40511824 |
| 44 | EWS_26573619_Chip-Seq_HEK293_Human | 1.37692754 |
| 45 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.34185114 |
| 46 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.32206230 |
| 47 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.26910335 |
| 48 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.25922760 |
| 49 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.22691779 |
| 50 | E2F7_22180533_ChIP-Seq_HELA_Human | 1.19744946 |
| 51 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.19180969 |
| 52 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.18476044 |
| 53 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.16282933 |
| 54 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.14249713 |
| 55 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.12048192 |
| 56 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.07171090 |
| 57 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.06140413 |
| 58 | P53_21459846_ChIP-Seq_SAOS-2_Human | 1.04563509 |
| 59 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.04208111 |
| 60 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.03891529 |
| 61 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.03694642 |
| 62 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.02842249 |
| 63 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.01717529 |
| 64 | ERA_21632823_ChIP-Seq_H3396_Human | 1.01414594 |
| 65 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.00093868 |
| 66 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 0.99947075 |
| 67 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 0.98957395 |
| 68 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 0.98951018 |
| 69 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 0.98880613 |
| 70 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.98619803 |
| 71 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 0.96631508 |
| 72 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 0.94837434 |
| 73 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 0.94588995 |
| 74 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 0.92592466 |
| 75 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.92232155 |
| 76 | CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse | 0.92058985 |
| 77 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 0.90729632 |
| 78 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.90685514 |
| 79 | FLI1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 0.87945208 |
| 80 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.87219078 |
| 81 | SA1_27219007_Chip-Seq_Bcells_Human | 0.86551974 |
| 82 | NCOR_22424771_ChIP-Seq_293T_Human | 0.86422015 |
| 83 | MYC_19829295_ChIP-Seq_ESCs_Human | 0.84646110 |
| 84 | E2F1_20622854_ChIP-Seq_HELA_Human | 0.84105154 |
| 85 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 0.83259225 |
| 86 | PHF8_20622853_ChIP-Seq_HELA_Human | 0.83033657 |
| 87 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.82944752 |
| 88 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.82224577 |
| 89 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 0.80977234 |
| 90 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.80691424 |
| 91 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.80691424 |
| 92 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 0.80455928 |
| 93 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 0.77661322 |
| 94 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.77024720 |
| 95 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 0.75751205 |
| 96 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.74307520 |
| 97 | GATA3_26560356_Chip-Seq_TH2_Human | 0.73992723 |
| 98 | FOXP1_21924763_ChIP-Seq_HESCs_Human | 0.73794848 |
| 99 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 0.73674965 |
| 100 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 0.73157491 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0010368_abnormal_lymphatic_system | 4.71570741 |
| 2 | MP0001873_stomach_inflammation | 4.50489891 |
| 3 | MP0004147_increased_porphyrin_level | 4.13245612 |
| 4 | MP0000604_amyloidosis | 3.39575282 |
| 5 | MP0003718_maternal_effect | 3.32661387 |
| 6 | MP0008875_abnormal_xenobiotic_pharmacok | 2.99448010 |
| 7 | MP0008872_abnormal_physiological_respon | 2.97088767 |
| 8 | MP0001835_abnormal_antigen_presentation | 2.72462186 |
| 9 | MP0003941_abnormal_skin_development | 2.71455203 |
| 10 | MP0001348_abnormal_lacrimal_gland | 2.41005765 |
| 11 | MP0001502_abnormal_circadian_rhythm | 2.28162365 |
| 12 | MP0000465_gastrointestinal_hemorrhage | 2.27264535 |
| 13 | MP0001853_heart_inflammation | 2.20768599 |
| 14 | MP0005645_abnormal_hypothalamus_physiol | 2.17495147 |
| 15 | MP0001879_abnormal_lymphatic_vessel | 2.06946050 |
| 16 | MP0002254_reproductive_system_inflammat | 2.05796387 |
| 17 | MP0003300_gastrointestinal_ulcer | 1.95844856 |
| 18 | MP0002234_abnormal_pharynx_morphology | 1.93956759 |
| 19 | MP0005084_abnormal_gallbladder_morpholo | 1.85313587 |
| 20 | MP0003283_abnormal_digestive_organ | 1.81451998 |
| 21 | MP0005167_abnormal_blood-brain_barrier | 1.77530954 |
| 22 | MP0002638_abnormal_pupillary_reflex | 1.76116454 |
| 23 | MP0003693_abnormal_embryo_hatching | 1.75884063 |
| 24 | MP0000372_irregular_coat_pigmentation | 1.73255167 |
| 25 | MP0006036_abnormal_mitochondrial_physio | 1.72714905 |
| 26 | MP0003786_premature_aging | 1.69804406 |
| 27 | MP0006082_CNS_inflammation | 1.67829278 |
| 28 | MP0003329_amyloid_beta_deposits | 1.61522846 |
| 29 | MP0009697_abnormal_copulation | 1.60672889 |
| 30 | MP0004782_abnormal_surfactant_physiolog | 1.59649134 |
| 31 | MP0002138_abnormal_hepatobiliary_system | 1.53529503 |
| 32 | MP0002876_abnormal_thyroid_physiology | 1.47139488 |
| 33 | MP0004142_abnormal_muscle_tone | 1.45225481 |
| 34 | MP0001881_abnormal_mammary_gland | 1.41680080 |
| 35 | MP0002277_abnormal_respiratory_mucosa | 1.41446252 |
| 36 | MP0002160_abnormal_reproductive_system | 1.38263587 |
| 37 | MP0005310_abnormal_salivary_gland | 1.37942370 |
| 38 | MP0003763_abnormal_thymus_physiology | 1.37915289 |
| 39 | MP0001790_abnormal_immune_system | 1.37539111 |
| 40 | MP0005387_immune_system_phenotype | 1.37539111 |
| 41 | MP0009333_abnormal_splenocyte_physiolog | 1.34629417 |
| 42 | MP0004043_abnormal_pH_regulation | 1.33232771 |
| 43 | MP0003646_muscle_fatigue | 1.32527102 |
| 44 | MP0003186_abnormal_redox_activity | 1.29298712 |
| 45 | MP0003806_abnormal_nucleotide_metabolis | 1.27821571 |
| 46 | MP0006035_abnormal_mitochondrial_morpho | 1.24947681 |
| 47 | MP0008058_abnormal_DNA_repair | 1.20138329 |
| 48 | MP0006276_abnormal_autonomic_nervous | 1.19210406 |
| 49 | MP0002163_abnormal_gland_morphology | 1.18265356 |
| 50 | MP0001905_abnormal_dopamine_level | 1.17265198 |
| 51 | MP0002148_abnormal_hypersensitivity_rea | 1.15581510 |
| 52 | MP0003656_abnormal_erythrocyte_physiolo | 1.13489320 |
| 53 | MP0005395_other_phenotype | 1.07774871 |
| 54 | MP0004084_abnormal_cardiac_muscle | 1.05520253 |
| 55 | MP0006292_abnormal_olfactory_placode | 1.03919175 |
| 56 | MP0009046_muscle_twitch | 0.99491881 |
| 57 | MP0001958_emphysema | 0.98329818 |
| 58 | MP0002751_abnormal_autonomic_nervous | 0.97917482 |
| 59 | MP0001529_abnormal_vocalization | 0.96608378 |
| 60 | MP0003567_abnormal_fetal_cardiomyocyte | 0.94660315 |
| 61 | MP0001663_abnormal_digestive_system | 0.93578736 |
| 62 | MP0001986_abnormal_taste_sensitivity | 0.93201489 |
| 63 | MP0002928_abnormal_bile_duct | 0.91508702 |
| 64 | MP0003866_abnormal_defecation | 0.90939951 |
| 65 | MP0005379_endocrine/exocrine_gland_phen | 0.90701416 |
| 66 | MP0004145_abnormal_muscle_electrophysio | 0.90403900 |
| 67 | MP0009745_abnormal_behavioral_response | 0.89899758 |
| 68 | MP0004381_abnormal_hair_follicle | 0.89641695 |
| 69 | MP0003252_abnormal_bile_duct | 0.89041519 |
| 70 | MP0003385_abnormal_body_wall | 0.88172060 |
| 71 | MP0000749_muscle_degeneration | 0.87853087 |
| 72 | MP0003936_abnormal_reproductive_system | 0.87621507 |
| 73 | MP0001800_abnormal_humoral_immune | 0.86876043 |
| 74 | MP0003303_peritoneal_inflammation | 0.86841394 |
| 75 | MP0002796_impaired_skin_barrier | 0.84295109 |
| 76 | MP0002693_abnormal_pancreas_physiology | 0.83675573 |
| 77 | MP0000627_abnormal_mammary_gland | 0.82211868 |
| 78 | MP0002405_respiratory_system_inflammati | 0.81670858 |
| 79 | MP0004957_abnormal_blastocyst_morpholog | 0.81548098 |
| 80 | MP0004885_abnormal_endolymph | 0.81479298 |
| 81 | MP0005671_abnormal_response_to | 0.81377492 |
| 82 | MP0000470_abnormal_stomach_morphology | 0.81223816 |
| 83 | MP0001984_abnormal_olfaction | 0.79995651 |
| 84 | MP0010094_abnormal_chromosome_stability | 0.78895059 |
| 85 | MP0005381_digestive/alimentary_phenotyp | 0.73123283 |
| 86 | MP0002938_white_spotting | 0.71364703 |
| 87 | MP0000747_muscle_weakness | 0.70964170 |
| 88 | MP0005551_abnormal_eye_electrophysiolog | 0.70512278 |
| 89 | MP0001968_abnormal_touch/_nociception | 0.70346078 |
| 90 | MP0001188_hyperpigmentation | 0.69636060 |
| 91 | MP0005319_abnormal_enzyme/_coenzyme | 0.68746744 |
| 92 | MP0004036_abnormal_muscle_relaxation | 0.68165981 |
| 93 | MP0005332_abnormal_amino_acid | 0.67188518 |
| 94 | MP0004215_abnormal_myocardial_fiber | 0.65126596 |
| 95 | MP0003119_abnormal_digestive_system | 0.64062431 |
| 96 | MP0005171_absent_coat_pigmentation | 0.63763365 |
| 97 | MP0002166_altered_tumor_susceptibility | 0.63760344 |
| 98 | MP0002006_tumorigenesis | 0.62979691 |
| 99 | MP0003011_delayed_dark_adaptation | 0.61420731 |
| 100 | MP0005330_cardiomyopathy | 0.61263760 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Increased hepatocellular lipid droplets (HP:0006565) | 5.84458411 |
| 2 | Lipid accumulation in hepatocytes (HP:0006561) | 5.57038069 |
| 3 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 4.99789358 |
| 4 | Renal Fanconi syndrome (HP:0001994) | 4.34888410 |
| 5 | Testicular atrophy (HP:0000029) | 4.29785573 |
| 6 | Mitochondrial inheritance (HP:0001427) | 4.22061001 |
| 7 | Exertional dyspnea (HP:0002875) | 4.15021102 |
| 8 | 3-Methylglutaconic aciduria (HP:0003535) | 4.13513979 |
| 9 | Acute necrotizing encephalopathy (HP:0006965) | 3.98249869 |
| 10 | Increased CSF lactate (HP:0002490) | 3.93994067 |
| 11 | Increased intramyocellular lipid droplets (HP:0012240) | 3.93222106 |
| 12 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 3.73018983 |
| 13 | Acute encephalopathy (HP:0006846) | 3.62493119 |
| 14 | Increased muscle lipid content (HP:0009058) | 3.56745890 |
| 15 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.53402628 |
| 16 | Increased serum lactate (HP:0002151) | 3.50670504 |
| 17 | Hepatocellular necrosis (HP:0001404) | 3.50471066 |
| 18 | Cerebral hypomyelination (HP:0006808) | 3.40459300 |
| 19 | Progressive macrocephaly (HP:0004481) | 3.19743010 |
| 20 | Hypoplasia of the pons (HP:0012110) | 3.06551489 |
| 21 | Type II lissencephaly (HP:0007260) | 3.01695434 |
| 22 | Hepatic necrosis (HP:0002605) | 2.99360602 |
| 23 | Microvesicular hepatic steatosis (HP:0001414) | 2.98064798 |
| 24 | Abnormality of the pons (HP:0007361) | 2.95447973 |
| 25 | Respiratory difficulties (HP:0002880) | 2.95054136 |
| 26 | Malignant hyperthermia (HP:0002047) | 2.91765981 |
| 27 | Aplastic anemia (HP:0001915) | 2.82682473 |
| 28 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.78182722 |
| 29 | Dyschromatopsia (HP:0007641) | 2.77955644 |
| 30 | Abnormal biliary tract physiology (HP:0012439) | 2.75956245 |
| 31 | Bile duct proliferation (HP:0001408) | 2.75956245 |
| 32 | Progressive muscle weakness (HP:0003323) | 2.73252759 |
| 33 | Exercise intolerance (HP:0003546) | 2.71909932 |
| 34 | Hyperphosphaturia (HP:0003109) | 2.71240499 |
| 35 | Optic disc pallor (HP:0000543) | 2.60562957 |
| 36 | Cerebellar dysplasia (HP:0007033) | 2.56988428 |
| 37 | Cerebral hemorrhage (HP:0001342) | 2.53076448 |
| 38 | Mesangial abnormality (HP:0001966) | 2.52428154 |
| 39 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.50493159 |
| 40 | Abnormality of the ileum (HP:0001549) | 2.49475153 |
| 41 | Hypoalbuminemia (HP:0003073) | 2.48352522 |
| 42 | Abnormal albumin level (HP:0012116) | 2.48352522 |
| 43 | Stomatitis (HP:0010280) | 2.48091379 |
| 44 | Pancreatic cysts (HP:0001737) | 2.47369511 |
| 45 | Shoulder girdle muscle weakness (HP:0003547) | 2.46224790 |
| 46 | Focal motor seizures (HP:0011153) | 2.45252651 |
| 47 | Abnormal urine phosphate concentration (HP:0012599) | 2.42320371 |
| 48 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.41818190 |
| 49 | Large for gestational age (HP:0001520) | 2.38101253 |
| 50 | Pelvic girdle muscle weakness (HP:0003749) | 2.36849784 |
| 51 | Lactic acidosis (HP:0003128) | 2.36262524 |
| 52 | Meckel diverticulum (HP:0002245) | 2.32697224 |
| 53 | Abnormality of urine glucose concentration (HP:0011016) | 2.32627371 |
| 54 | Glycosuria (HP:0003076) | 2.32627371 |
| 55 | Pendular nystagmus (HP:0012043) | 2.29350392 |
| 56 | Congenital stationary night blindness (HP:0007642) | 2.29310057 |
| 57 | Cerebral edema (HP:0002181) | 2.28933116 |
| 58 | Abnormality of midbrain morphology (HP:0002418) | 2.28125385 |
| 59 | Molar tooth sign on MRI (HP:0002419) | 2.28125385 |
| 60 | Absent thumb (HP:0009777) | 2.26626046 |
| 61 | Neuroendocrine neoplasm (HP:0100634) | 2.25825912 |
| 62 | Abnormality of renal resorption (HP:0011038) | 2.21659162 |
| 63 | IgG deficiency (HP:0004315) | 2.17290350 |
| 64 | Autoimmune hemolytic anemia (HP:0001890) | 2.16401903 |
| 65 | Colon cancer (HP:0003003) | 2.12979332 |
| 66 | Neoplasm of head and neck (HP:0012288) | 2.10467653 |
| 67 | Esophageal neoplasm (HP:0100751) | 2.10467653 |
| 68 | Chorioretinal atrophy (HP:0000533) | 2.08117793 |
| 69 | Pancytopenia (HP:0001876) | 2.07764445 |
| 70 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 2.07064800 |
| 71 | Neoplasm of the peripheral nervous system (HP:0100007) | 2.04892903 |
| 72 | Fatigue (HP:0012378) | 2.04178137 |
| 73 | Emotional lability (HP:0000712) | 2.00664129 |
| 74 | Congenital, generalized hypertrichosis (HP:0004540) | 1.99749300 |
| 75 | Pheochromocytoma (HP:0002666) | 1.94972401 |
| 76 | Abnormality of the hip-girdle musculature (HP:0001445) | 1.94023025 |
| 77 | Abnormality of the musculature of the pelvis (HP:0001469) | 1.94023025 |
| 78 | Premature ovarian failure (HP:0008209) | 1.93604679 |
| 79 | Respiratory failure (HP:0002878) | 1.91499005 |
| 80 | Optic nerve coloboma (HP:0000588) | 1.90871029 |
| 81 | Respiratory insufficiency due to muscle weakness (HP:0002747) | 1.84996363 |
| 82 | Arthropathy (HP:0003040) | 1.83290579 |
| 83 | Amniotic constriction ring (HP:0009775) | 1.82496944 |
| 84 | Abnormality of placental membranes (HP:0011409) | 1.82496944 |
| 85 | Tubular atrophy (HP:0000092) | 1.82479163 |
| 86 | Lethargy (HP:0001254) | 1.80820823 |
| 87 | Abnormality of the preputium (HP:0100587) | 1.79705813 |
| 88 | Conjunctival hamartoma (HP:0100780) | 1.75585382 |
| 89 | Progressive inability to walk (HP:0002505) | 1.74493754 |
| 90 | Attenuation of retinal blood vessels (HP:0007843) | 1.74459581 |
| 91 | Polydipsia (HP:0001959) | 1.73639509 |
| 92 | Abnormal drinking behavior (HP:0030082) | 1.73639509 |
| 93 | Leukodystrophy (HP:0002415) | 1.72800291 |
| 94 | Renal tubular dysfunction (HP:0000124) | 1.72162049 |
| 95 | Prolonged partial thromboplastin time (HP:0003645) | 1.71831573 |
| 96 | Methylmalonic aciduria (HP:0012120) | 1.70338936 |
| 97 | Squamous cell carcinoma (HP:0002860) | 1.69218769 |
| 98 | Weak cry (HP:0001612) | 1.69000920 |
| 99 | Abnormality of the carotid arteries (HP:0005344) | 1.68925612 |
| 100 | Abnormality of the renal cortex (HP:0011035) | 1.68449144 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | PBK | 4.60844620 |
| 2 | TIE1 | 4.34668959 |
| 3 | EIF2AK1 | 4.27942393 |
| 4 | TSSK6 | 4.25487744 |
| 5 | EIF2AK3 | 2.96438794 |
| 6 | BUB1 | 2.82564747 |
| 7 | CDK8 | 2.75235574 |
| 8 | NUAK1 | 2.54647856 |
| 9 | NLK | 2.32813807 |
| 10 | NME1 | 2.31225600 |
| 11 | MST4 | 2.19846772 |
| 12 | TEC | 2.11682709 |
| 13 | FES | 1.96968197 |
| 14 | ADRBK2 | 1.96112769 |
| 15 | PINK1 | 1.88951986 |
| 16 | SRPK1 | 1.79058113 |
| 17 | MAPKAPK3 | 1.73321706 |
| 18 | GRK1 | 1.66468357 |
| 19 | TLK1 | 1.60101264 |
| 20 | TAOK3 | 1.58254927 |
| 21 | TRIM28 | 1.55258612 |
| 22 | ZAK | 1.50463736 |
| 23 | OBSCN | 1.46625458 |
| 24 | WNK4 | 1.45047525 |
| 25 | MAP4K2 | 1.42875934 |
| 26 | MAP3K14 | 1.40780035 |
| 27 | NME2 | 1.36762903 |
| 28 | NEK1 | 1.35148371 |
| 29 | PHKG2 | 1.31210538 |
| 30 | PHKG1 | 1.31210538 |
| 31 | VRK2 | 1.31046195 |
| 32 | CCNB1 | 1.30611693 |
| 33 | DYRK3 | 1.17306344 |
| 34 | SIK3 | 1.16993833 |
| 35 | TAOK1 | 1.15041774 |
| 36 | AKT3 | 1.08049974 |
| 37 | TNIK | 1.02355287 |
| 38 | PLK3 | 1.01335425 |
| 39 | MAPK15 | 0.99111769 |
| 40 | CSK | 0.95279535 |
| 41 | ITK | 0.95234010 |
| 42 | ACVR1B | 0.94241378 |
| 43 | STK16 | 0.92544329 |
| 44 | STK4 | 0.90470393 |
| 45 | TYRO3 | 0.86684807 |
| 46 | MAPK13 | 0.85359939 |
| 47 | PASK | 0.85244917 |
| 48 | FER | 0.83687520 |
| 49 | KIT | 0.82876978 |
| 50 | TXK | 0.79532299 |
| 51 | PAK4 | 0.76275285 |
| 52 | BMPR1B | 0.74199044 |
| 53 | FRK | 0.71331119 |
| 54 | RPS6KA5 | 0.70383414 |
| 55 | MUSK | 0.69604784 |
| 56 | ADRBK1 | 0.68830384 |
| 57 | EIF2AK2 | 0.68469482 |
| 58 | PLK1 | 0.68087661 |
| 59 | TGFBR1 | 0.67329506 |
| 60 | MATK | 0.66955057 |
| 61 | NTRK1 | 0.65938096 |
| 62 | VRK1 | 0.64268715 |
| 63 | TGFBR2 | 0.60856086 |
| 64 | KDR | 0.58643978 |
| 65 | IKBKB | 0.58112079 |
| 66 | DMPK | 0.55936153 |
| 67 | CSNK2A1 | 0.53196608 |
| 68 | INSRR | 0.51940548 |
| 69 | PKN1 | 0.50900056 |
| 70 | TYK2 | 0.44065013 |
| 71 | ALK | 0.43257063 |
| 72 | CSNK2A2 | 0.42811440 |
| 73 | DYRK2 | 0.39122421 |
| 74 | BTK | 0.38770351 |
| 75 | MAP2K6 | 0.38600626 |
| 76 | PIK3CG | 0.36206908 |
| 77 | MAP3K3 | 0.35396556 |
| 78 | IKBKE | 0.34819336 |
| 79 | CAMK1 | 0.34526571 |
| 80 | MKNK2 | 0.33768335 |
| 81 | MAPK11 | 0.33726352 |
| 82 | CSNK1A1 | 0.33719028 |
| 83 | TAOK2 | 0.32548458 |
| 84 | PRKG1 | 0.32179276 |
| 85 | CHEK2 | 0.26988496 |
| 86 | CSNK1A1L | 0.26666254 |
| 87 | ILK | 0.25399953 |
| 88 | INSR | 0.25061253 |
| 89 | AKT2 | 0.24697892 |
| 90 | RPS6KB2 | 0.24613149 |
| 91 | ATR | 0.24133109 |
| 92 | PIM2 | 0.23401072 |
| 93 | STK39 | 0.23325433 |
| 94 | BCR | 0.22790507 |
| 95 | CSNK1E | 0.22616419 |
| 96 | WNK1 | 0.22119121 |
| 97 | LCK | 0.22117318 |
| 98 | CSNK1G3 | 0.21807557 |
| 99 | PRKCQ | 0.21135150 |
| 100 | CDK3 | 0.20723363 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.69492280 |
| 2 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 4.21637256 |
| 3 | RNA polymerase_Homo sapiens_hsa03020 | 4.09242464 |
| 4 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.17764543 |
| 5 | Protein export_Homo sapiens_hsa03060 | 2.91361517 |
| 6 | Ribosome_Homo sapiens_hsa03010 | 2.76319248 |
| 7 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.71492224 |
| 8 | Parkinsons disease_Homo sapiens_hsa05012 | 2.65857024 |
| 9 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.52554541 |
| 10 | Allograft rejection_Homo sapiens_hsa05330 | 2.30595146 |
| 11 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 2.29290243 |
| 12 | Basal transcription factors_Homo sapiens_hsa03022 | 2.25395357 |
| 13 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.24516580 |
| 14 | Asthma_Homo sapiens_hsa05310 | 2.15659658 |
| 15 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.92550913 |
| 16 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.80472597 |
| 17 | Alzheimers disease_Homo sapiens_hsa05010 | 1.76207484 |
| 18 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.75451573 |
| 19 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.75389117 |
| 20 | Huntingtons disease_Homo sapiens_hsa05016 | 1.70809675 |
| 21 | RNA transport_Homo sapiens_hsa03013 | 1.63818687 |
| 22 | Spliceosome_Homo sapiens_hsa03040 | 1.61204113 |
| 23 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.60971593 |
| 24 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.56469860 |
| 25 | Mismatch repair_Homo sapiens_hsa03430 | 1.56353816 |
| 26 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.46169167 |
| 27 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.39373918 |
| 28 | Purine metabolism_Homo sapiens_hsa00230 | 1.38352178 |
| 29 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.33459132 |
| 30 | DNA replication_Homo sapiens_hsa03030 | 1.32307060 |
| 31 | RNA degradation_Homo sapiens_hsa03018 | 1.27347131 |
| 32 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.24447205 |
| 33 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.23975354 |
| 34 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.23463301 |
| 35 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.21936716 |
| 36 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.16810548 |
| 37 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.08106912 |
| 38 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.03266908 |
| 39 | Homologous recombination_Homo sapiens_hsa03440 | 1.02100100 |
| 40 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.97995717 |
| 41 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.93656294 |
| 42 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.92070481 |
| 43 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.90537563 |
| 44 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.89469886 |
| 45 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.83532486 |
| 46 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.77191338 |
| 47 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.76932932 |
| 48 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.76410663 |
| 49 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.76077918 |
| 50 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.75933838 |
| 51 | Mineral absorption_Homo sapiens_hsa04978 | 0.72199377 |
| 52 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.71955453 |
| 53 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.71292153 |
| 54 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.70175413 |
| 55 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.69706887 |
| 56 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.67967128 |
| 57 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.67957588 |
| 58 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.67620068 |
| 59 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.67286737 |
| 60 | Measles_Homo sapiens_hsa05162 | 0.66454515 |
| 61 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.66106393 |
| 62 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.65754349 |
| 63 | Metabolic pathways_Homo sapiens_hsa01100 | 0.61983747 |
| 64 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.61108202 |
| 65 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.60708394 |
| 66 | Olfactory transduction_Homo sapiens_hsa04740 | 0.59035063 |
| 67 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.58062841 |
| 68 | Phototransduction_Homo sapiens_hsa04744 | 0.54861894 |
| 69 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.52093282 |
| 70 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.50060958 |
| 71 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.48905984 |
| 72 | Sulfur relay system_Homo sapiens_hsa04122 | 0.47944557 |
| 73 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.44662798 |
| 74 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.43598125 |
| 75 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.39511136 |
| 76 | Peroxisome_Homo sapiens_hsa04146 | 0.39274810 |
| 77 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.38765095 |
| 78 | Base excision repair_Homo sapiens_hsa03410 | 0.38402442 |
| 79 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.37818378 |
| 80 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.37731674 |
| 81 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.35152857 |
| 82 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.34095540 |
| 83 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.31470144 |
| 84 | Circadian rhythm_Homo sapiens_hsa04710 | 0.29760297 |
| 85 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.27870587 |
| 86 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.26387406 |
| 87 | Retinol metabolism_Homo sapiens_hsa00830 | 0.25671170 |
| 88 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.25586675 |
| 89 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.22482970 |
| 90 | HTLV-I infection_Homo sapiens_hsa05166 | 0.22297572 |
| 91 | ABC transporters_Homo sapiens_hsa02010 | 0.20639660 |
| 92 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.20192637 |
| 93 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.19708353 |
| 94 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.19491742 |
| 95 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.15401668 |
| 96 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.14807323 |
| 97 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.12400827 |
| 98 | Carbon metabolism_Homo sapiens_hsa01200 | 0.10489674 |
| 99 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.10454811 |
| 100 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.06785340 |

