PHC3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1protein K11-linked deubiquitination (GO:0035871)4.32520711
2interkinetic nuclear migration (GO:0022027)4.24263528
3antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.60342291
4monoubiquitinated protein deubiquitination (GO:0035520)3.58294468
5histone H3-K4 trimethylation (GO:0080182)3.45660054
6cellular response to ethanol (GO:0071361)3.41519275
7regulation of germinal center formation (GO:0002634)3.25574754
8positive regulation of gamma-delta T cell activation (GO:0046645)3.25479097
9neural tube formation (GO:0001841)3.19692964
10positive regulation of granulocyte differentiation (GO:0030854)3.17495325
11negative regulation of cell killing (GO:0031342)3.13727319
12negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.13727319
13protein K48-linked deubiquitination (GO:0071108)3.10643249
14pericardium development (GO:0060039)3.03669697
15negative T cell selection (GO:0043383)2.96434298
16negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.94804795
17negative regulation of translation, ncRNA-mediated (GO:0040033)2.94804795
18regulation of translation, ncRNA-mediated (GO:0045974)2.94804795
19regulation of establishment of cell polarity (GO:2000114)2.88515837
20negative thymic T cell selection (GO:0045060)2.86249075
21nerve growth factor signaling pathway (GO:0038180)2.85055578
22protein localization to Golgi apparatus (GO:0034067)2.79011356
23locomotory exploration behavior (GO:0035641)2.78278269
24regulation of T cell tolerance induction (GO:0002664)2.77373408
25retrograde transport, vesicle recycling within Golgi (GO:0000301)2.75811110
26protein prenylation (GO:0018342)2.75097276
27prenylation (GO:0097354)2.75097276
28magnesium ion transport (GO:0015693)2.74507864
29replicative senescence (GO:0090399)2.74131729
30sulfation (GO:0051923)2.72348113
31cytoplasmic mRNA processing body assembly (GO:0033962)2.70906917
32hepatocyte apoptotic process (GO:0097284)2.70664298
33protein K63-linked deubiquitination (GO:0070536)2.67449170
34negative regulation of T-helper cell differentiation (GO:0045623)2.66828782
35negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)2.66828782
36regulation of ARF protein signal transduction (GO:0032012)2.64866127
37regulation of energy homeostasis (GO:2000505)2.62547088
38nucleus localization (GO:0051647)2.62030638
39microtubule anchoring (GO:0034453)2.60289879
40regulation of gamma-delta T cell differentiation (GO:0045586)2.60101994
41positive T cell selection (GO:0043368)2.59654565
42alpha-beta T cell differentiation (GO:0046632)2.59040823
43dentate gyrus development (GO:0021542)2.57751771
44protein targeting to Golgi (GO:0000042)2.57129076
45positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.53621526
46prostate gland growth (GO:0060736)2.53026472
47establishment of protein localization to Golgi (GO:0072600)2.52166390
48response to pheromone (GO:0019236)2.51754540
49cAMP catabolic process (GO:0006198)2.51469596
50regulation of establishment or maintenance of cell polarity (GO:0032878)2.49202071
51positive thymic T cell selection (GO:0045059)2.48963690
52positive regulation of developmental pigmentation (GO:0048087)2.46148659
53T cell mediated immunity (GO:0002456)2.45427221
54early endosome to late endosome transport (GO:0045022)2.43827171
55keratinocyte development (GO:0003334)2.43176920
56regulation of pigment cell differentiation (GO:0050932)2.43037046
57regulation of gamma-delta T cell activation (GO:0046643)2.42076941
58cyclic nucleotide catabolic process (GO:0009214)2.41390233
59regulation of hippo signaling (GO:0035330)2.40707035
60negative regulation of neurotransmitter transport (GO:0051589)2.40649605
61histone mRNA catabolic process (GO:0071044)2.40532462
62interferon-gamma secretion (GO:0072643)2.40104401
63Golgi to endosome transport (GO:0006895)2.40081432
64peptidyl-lysine methylation (GO:0018022)2.39720491
65definitive hemopoiesis (GO:0060216)2.39542042
66regulation of antigen receptor-mediated signaling pathway (GO:0050854)2.37947455
67tolerance induction (GO:0002507)2.37913682
68growth hormone receptor signaling pathway (GO:0060396)2.36927141
69snRNA transcription (GO:0009301)2.36278280
70embryonic hemopoiesis (GO:0035162)2.36141364
71UDP-N-acetylglucosamine metabolic process (GO:0006047)2.35607337
72T cell selection (GO:0045058)2.35221865
73regulation of protein glycosylation (GO:0060049)2.35173340
74cerebellar Purkinje cell differentiation (GO:0021702)2.35143257
75alpha-beta T cell activation (GO:0046631)2.33825118
76histone H3-K4 methylation (GO:0051568)2.33163163
77response to interleukin-15 (GO:0070672)2.33095504
78insulin-like growth factor receptor signaling pathway (GO:0048009)2.33050673
79kidney morphogenesis (GO:0060993)2.32819001
80thymic T cell selection (GO:0045061)2.32579646
81regulation of DNA endoreduplication (GO:0032875)2.32520836
82fucose catabolic process (GO:0019317)2.30477134
83L-fucose metabolic process (GO:0042354)2.30477134
84L-fucose catabolic process (GO:0042355)2.30477134
85relaxation of cardiac muscle (GO:0055119)2.30220058
86positive regulation of natural killer cell differentiation (GO:0032825)2.29649883
87indolalkylamine metabolic process (GO:0006586)2.29513387
88histone H3-K9 modification (GO:0061647)2.28947182
89positive regulation of phosphoprotein phosphatase activity (GO:0032516)2.28093571
90histone H3-K9 methylation (GO:0051567)2.27904248
91positive regulation of tolerance induction (GO:0002645)2.27695077
92positive regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060213)2.26340203
93regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060211)2.26340203
94positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.23496455
95intra-Golgi vesicle-mediated transport (GO:0006891)2.23176233
96positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO2.22344191
97regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:1900151)2.22344191
98embryonic retina morphogenesis in camera-type eye (GO:0060059)2.19407412
99synaptic vesicle maturation (GO:0016188)2.17730237
100regulation of regulatory T cell differentiation (GO:0045589)2.15678245
101dendrite morphogenesis (GO:0048813)2.14776801
102regulation of interleukin-12 biosynthetic process (GO:0045075)2.11189738
103L-amino acid import (GO:0043092)2.10965773
104neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976)2.09007057
105positive regulation of histone deacetylation (GO:0031065)2.08521332
106regulation of tolerance induction (GO:0002643)2.07294401
107cellular response to interleukin-15 (GO:0071350)2.06787172
108cellular potassium ion homeostasis (GO:0030007)2.05431931
109cellular response to growth hormone stimulus (GO:0071378)2.05103609
110regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition 2.04513063
111positive regulation of Rap GTPase activity (GO:0032854)2.04149084
112lipid translocation (GO:0034204)2.03569250
113phospholipid translocation (GO:0045332)2.03569250
114peptidyl-lysine trimethylation (GO:0018023)2.01940074
115positive regulation of excitatory postsynaptic membrane potential (GO:2000463)2.00489056
116establishment of nucleus localization (GO:0040023)1.99283260
117activated T cell proliferation (GO:0050798)1.96208709
118JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)1.93475544
119regulation of Rap GTPase activity (GO:0032317)1.92574254
120interferon-gamma production (GO:0032609)1.92193204
121phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)1.92126018
122regulation of histone deacetylation (GO:0031063)1.91073981
123I-kappaB phosphorylation (GO:0007252)1.90964181
124regulation of short-term neuronal synaptic plasticity (GO:0048172)1.90333392
125lung lobe morphogenesis (GO:0060463)1.89609355
126heterotypic cell-cell adhesion (GO:0034113)1.88574258
127antigen processing and presentation of endogenous peptide antigen (GO:0002483)1.86788052
128antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)1.86788052
129positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr1.86538935
130potassium ion import (GO:0010107)1.85969998
131regulation of isotype switching to IgG isotypes (GO:0048302)1.84985891
132sodium ion export (GO:0071436)1.84963911
133peptidyl-threonine phosphorylation (GO:0018107)1.84698216
134histone H3-K36 demethylation (GO:0070544)1.83589038
135T cell receptor signaling pathway (GO:0050852)1.82642776
136antigen processing and presentation of endogenous antigen (GO:0019883)1.82004369
137clathrin coat assembly (GO:0048268)1.81946785
138regulation of B cell receptor signaling pathway (GO:0050855)1.81894493
139positive regulation of mRNA catabolic process (GO:0061014)1.81702724
140regulation of clathrin-mediated endocytosis (GO:2000369)1.80981219
141regulation of mRNA catabolic process (GO:0061013)1.80859879
142regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act1.79595459
143vocalization behavior (GO:0071625)1.79593659
144ionotropic glutamate receptor signaling pathway (GO:0035235)1.79033623
145peptidyl-tyrosine autophosphorylation (GO:0038083)1.77591982
146CD4-positive, alpha-beta T cell differentiation (GO:0043367)1.77513512
147T cell costimulation (GO:0031295)1.77284861
148peptidyl-threonine modification (GO:0018210)1.77256636
149face morphogenesis (GO:0060325)1.77233724
150phosphatidylinositol dephosphorylation (GO:0046856)1.77133072
151T-helper cell differentiation (GO:0042093)1.75830204
152CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294)1.75830204
153coronary vasculature morphogenesis (GO:0060977)1.75345159
154lateral sprouting from an epithelium (GO:0060601)1.74460292
155mannose metabolic process (GO:0006013)1.74186328
156regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)1.74169799
157lymphocyte costimulation (GO:0031294)1.73856172
158cortical actin cytoskeleton organization (GO:0030866)1.73497120
159positive regulation of interleukin-2 production (GO:0032743)1.72910194

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXP3_17237761_ChIP-ChIP_TREG_Mouse3.46810084
2FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse3.27198094
3STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.96409984
4SMAD_19615063_ChIP-ChIP_OVARY_Human2.54306042
5GBX2_23144817_ChIP-Seq_PC3_Human2.42949093
6VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human2.21437391
7CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.16277136
8* RUNX_20019798_ChIP-Seq_JUKART_Human1.96842931
9FUS_26573619_Chip-Seq_HEK293_Human1.95165750
10ZNF217_24962896_ChIP-Seq_MCF-7_Human1.89642799
11SALL1_21062744_ChIP-ChIP_HESCs_Human1.88760608
12FLI1_27457419_Chip-Seq_LIVER_Mouse1.88165020
13DROSHA_22980978_ChIP-Seq_HELA_Human1.84746947
14GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.84255473
15AR_21572438_ChIP-Seq_LNCaP_Human1.80128670
16GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.75360553
17VDR_22108803_ChIP-Seq_LS180_Human1.72201225
18ZNF274_21170338_ChIP-Seq_K562_Hela1.67880517
19ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.66238190
20* EWS_26573619_Chip-Seq_HEK293_Human1.64769294
21TP53_16413492_ChIP-PET_HCT116_Human1.64563351
22STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.62803003
23* MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.62307225
24CDX2_19796622_ChIP-Seq_MESCs_Mouse1.62014872
25SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.61566935
26AHR_22903824_ChIP-Seq_MCF-7_Human1.54983292
27NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.52415793
28IGF1R_20145208_ChIP-Seq_DFB_Human1.51628901
29SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.51194657
30EZH2_22144423_ChIP-Seq_EOC_Human1.49758371
31CTBP2_25329375_ChIP-Seq_LNCAP_Human1.49530329
32PCGF2_27294783_Chip-Seq_ESCs_Mouse1.49489437
33PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.47008220
34EZH2_27294783_Chip-Seq_NPCs_Mouse1.46769196
35ARNT_22903824_ChIP-Seq_MCF-7_Human1.45137092
36SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.45107263
37SUZ12_27294783_Chip-Seq_NPCs_Mouse1.44011917
38AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.43892273
39SMAD4_21799915_ChIP-Seq_A2780_Human1.43199461
40CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.42464136
41PIAS1_25552417_ChIP-Seq_VCAP_Human1.42238359
42PCGF2_27294783_Chip-Seq_NPCs_Mouse1.41100191
43RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.39274951
44BCAT_22108803_ChIP-Seq_LS180_Human1.37187815
45CTBP1_25329375_ChIP-Seq_LNCAP_Human1.36575899
46CTNNB1_20460455_ChIP-Seq_HCT116_Human1.35219268
47SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.34990171
48UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.34486237
49MTF2_20144788_ChIP-Seq_MESCs_Mouse1.31948208
50* FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.31522606
51NFE2_27457419_Chip-Seq_LIVER_Mouse1.31242146
52IRF8_22096565_ChIP-ChIP_GC-B_Human1.30514550
53GATA2_21666600_ChIP-Seq_HMVEC_Human1.29402804
54FLI1_21867929_ChIP-Seq_TH2_Mouse1.29297011
55JARID2_20064375_ChIP-Seq_MESCs_Mouse1.29047993
56ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.26840734
57RNF2_18974828_ChIP-Seq_MESCs_Mouse1.26673195
58EZH2_18974828_ChIP-Seq_MESCs_Mouse1.26673195
59FOXM1_26456572_ChIP-Seq_MCF-7_Human1.23856396
60NOTCH1_21737748_ChIP-Seq_TLL_Human1.23790033
61SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.23133969
62POU3F2_20337985_ChIP-ChIP_501MEL_Human1.22957167
63ESR1_20079471_ChIP-ChIP_T-47D_Human1.22653576
64IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.22427212
65STAT3_23295773_ChIP-Seq_U87_Human1.21934818
66EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.21755662
67P53_22387025_ChIP-Seq_ESCs_Mouse1.21470746
68BP1_19119308_ChIP-ChIP_Hs578T_Human1.20339830
69* E2F1_18555785_Chip-Seq_ESCs_Mouse1.20197420
70CBP_20019798_ChIP-Seq_JUKART_Human1.19467531
71IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.19467531
72SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.18277722
73SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.18216064
74CRX_20693478_ChIP-Seq_RETINA_Mouse1.18172582
75WT1_25993318_ChIP-Seq_PODOCYTE_Human1.17909193
76Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.16908492
77RNF2_27304074_Chip-Seq_ESCs_Mouse1.14723828
78OCT4_21477851_ChIP-Seq_ESCs_Mouse1.14322452
79RXR_22108803_ChIP-Seq_LS180_Human1.12956524
80GATA1_22025678_ChIP-Seq_K562_Human1.12074500
81TCF4_23295773_ChIP-Seq_U87_Human1.11543312
82VDR_24787735_ChIP-Seq_THP-1_Human1.11275605
83SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.11101363
84CDX2_22108803_ChIP-Seq_LS180_Human1.10206894
85EP300_21415370_ChIP-Seq_HL-1_Mouse1.10096274
86STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.09293398
87TCF4_22108803_ChIP-Seq_LS180_Human1.09213852
88CMYC_18555785_Chip-Seq_ESCs_Mouse1.08407102
89SOX2_21211035_ChIP-Seq_LN229_Gbm1.08056730
90ZFP57_27257070_Chip-Seq_ESCs_Mouse1.08042142
91SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.07243923
92TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.07184521
93SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse1.06933672
94TAF15_26573619_Chip-Seq_HEK293_Human1.06872227
95TOP2B_26459242_ChIP-Seq_MCF-7_Human1.06760936
96KDM2B_26808549_Chip-Seq_REH_Human1.06492638
97OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.06014350
98* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.05213673
99SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.05153580
100* P300_19829295_ChIP-Seq_ESCs_Human1.05107771
101* PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.04705313
102* BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.04370338
103AR_25329375_ChIP-Seq_VCAP_Human1.04335465
104TP53_18474530_ChIP-ChIP_U2OS_Human1.04242083
105FOXA2_19822575_ChIP-Seq_HepG2_Human1.04173465
106TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.04071054
107EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.03870102
108SUZ12_18555785_Chip-Seq_ESCs_Mouse1.03690199
109P300_18555785_Chip-Seq_ESCs_Mouse1.03352431
110GATA3_26560356_Chip-Seq_TH2_Human1.02793704
111BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.02578934
112SMRT_27268052_Chip-Seq_Bcells_Human1.02432037
113TCF4_18268006_ChIP-ChIP_LS174T_Human1.02060518
114* IRF8_27001747_Chip-Seq_BMDM_Mouse1.01786356
115RUNX2_22187159_ChIP-Seq_PCA_Human1.01290809
116FOXO3_23340844_ChIP-Seq_DLD1_Human1.01001003
117NR3C1_23031785_ChIP-Seq_PC12_Mouse1.00858980
118* TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.00098459
119STAT3_18555785_Chip-Seq_ESCs_Mouse1.00029594
120AR_19668381_ChIP-Seq_PC3_Human0.99814234
121JARID2_20075857_ChIP-Seq_MESCs_Mouse0.99330950
122MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.99222223
123WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.99095393
124NR3C1_21868756_ChIP-Seq_MCF10A_Human0.98490807
125ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.97772519
126SMAD3_21741376_ChIP-Seq_EPCs_Human0.97763722
127EED_16625203_ChIP-ChIP_MESCs_Mouse0.97078928
128FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.96734402
129NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.96154154
130NRF2_20460467_ChIP-Seq_MEFs_Mouse0.96154154
131POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.95311469
132TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.95311469
133NANOG_18555785_Chip-Seq_ESCs_Mouse0.95193640
134YAP1_20516196_ChIP-Seq_MESCs_Mouse0.95141827
135TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.94686853
136ER_23166858_ChIP-Seq_MCF-7_Human0.94263614
137DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.94162544
138SOX9_24532713_ChIP-Seq_HFSC_Mouse0.93424547
139TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.91556278
140PRDM14_20953172_ChIP-Seq_ESCs_Human0.91001343
141CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse0.90907834
142SMAD4_21741376_ChIP-Seq_HESCs_Human0.90415824
143CJUN_26792858_Chip-Seq_BT549_Human0.90328404
144SUZ12_27294783_Chip-Seq_ESCs_Mouse0.90290148
145RARB_27405468_Chip-Seq_BRAIN_Mouse0.90021216
146SMAD3_21741376_ChIP-Seq_HESCs_Human0.89529161
147EZH2_27294783_Chip-Seq_ESCs_Mouse0.89207353

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000569_abnormal_digit_pigmentation5.57443991
2MP0003300_gastrointestinal_ulcer3.54119828
3MP0003045_fibrosis3.26562005
4MP0008057_abnormal_DNA_replication3.16341300
5MP0002166_altered_tumor_susceptibility2.83221041
6MP0009780_abnormal_chondrocyte_physiolo2.52954572
7MP0004859_abnormal_synaptic_plasticity2.52095175
8MP0002138_abnormal_hepatobiliary_system2.29132011
9MP0002009_preneoplasia2.26656548
10MP0002006_tumorigenesis2.19875561
11MP0001299_abnormal_eye_distance/2.07350987
12MP0008877_abnormal_DNA_methylation2.05209458
13MP0005075_abnormal_melanosome_morpholog2.04794161
14MP0000427_abnormal_hair_cycle1.99922516
15MP0001873_stomach_inflammation1.97479862
16MP0003646_muscle_fatigue1.94128423
17MP0004381_abnormal_hair_follicle1.88087503
18MP0005671_abnormal_response_to1.82193721
19MP0003172_abnormal_lysosome_physiology1.74499046
20MP0005310_abnormal_salivary_gland1.73794312
21MP0003183_abnormal_peptide_metabolism1.71011651
22MP0002254_reproductive_system_inflammat1.70694262
23MP0004043_abnormal_pH_regulation1.68348401
24MP0003195_calcinosis1.66102032
25MP0003763_abnormal_thymus_physiology1.65631694
26MP0005409_darkened_coat_color1.64202218
27MP0004510_myositis1.61899293
28MP0001790_abnormal_immune_system1.59053093
29MP0005387_immune_system_phenotype1.59053093
30MP0005379_endocrine/exocrine_gland_phen1.58092126
31MP0005551_abnormal_eye_electrophysiolog1.56804362
32MP0003690_abnormal_glial_cell1.53978742
33MP0008961_abnormal_basal_metabolism1.51792890
34MP0003091_abnormal_cell_migration1.47185571
35MP0008569_lethality_at_weaning1.44947044
36MP0005389_reproductive_system_phenotype1.41197521
37MP0000920_abnormal_myelination1.38036631
38MP0004130_abnormal_muscle_cell1.37210298
39MP0005174_abnormal_tail_pigmentation1.33228430
40MP0003635_abnormal_synaptic_transmissio1.32322138
41MP0002928_abnormal_bile_duct1.29396178
42MP0003787_abnormal_imprinting1.28545837
43MP0002837_dystrophic_cardiac_calcinosis1.27690874
44MP0001486_abnormal_startle_reflex1.27436924
45MP0005076_abnormal_cell_differentiation1.26432863
46MP0001835_abnormal_antigen_presentation1.26418037
47MP0000685_abnormal_immune_system1.23743714
48MP0002998_abnormal_bone_remodeling1.22544307
49MP0001800_abnormal_humoral_immune1.22024059
50MP0002160_abnormal_reproductive_system1.21207015
51MP0002168_other_aberrant_phenotype1.21037112
52MP0002095_abnormal_skin_pigmentation1.19337542
53MP0001919_abnormal_reproductive_system1.18252328
54MP0001986_abnormal_taste_sensitivity1.17756314
55MP0005645_abnormal_hypothalamus_physiol1.15831684
56MP0004142_abnormal_muscle_tone1.15766373
57MP0005253_abnormal_eye_physiology1.15073272
58MP0000631_abnormal_neuroendocrine_gland1.14876924
59MP0002396_abnormal_hematopoietic_system1.14626352
60MP0003866_abnormal_defecation1.14384470
61MP0001958_emphysema1.13066671
62MP0003303_peritoneal_inflammation1.11081361
63MP0005187_abnormal_penis_morphology1.10086542
64MP0000689_abnormal_spleen_morphology1.09550434
65MP0005646_abnormal_pituitary_gland1.09313215
66MP0004947_skin_inflammation1.09151633
67MP0010678_abnormal_skin_adnexa1.08594343
68MP0001851_eye_inflammation1.08447543
69MP0001501_abnormal_sleep_pattern1.08431904
70MP0000372_irregular_coat_pigmentation1.06426019
71MP0002693_abnormal_pancreas_physiology1.05906255
72MP0009046_muscle_twitch1.05763109
73MP0009384_cardiac_valve_regurgitation1.03631142
74MP0002638_abnormal_pupillary_reflex1.03179213
75MP0002933_joint_inflammation1.01803817
76MP0005000_abnormal_immune_tolerance1.01595343
77MP0002909_abnormal_adrenal_gland1.01172054
78MP0002723_abnormal_immune_serum1.00878525
79MP0000383_abnormal_hair_follicle0.99912685
80MP0000371_diluted_coat_color0.99823112
81MP0006072_abnormal_retinal_apoptosis0.97213716
82MP0002064_seizures0.96784325
83MP0002876_abnormal_thyroid_physiology0.96550109
84MP0000733_abnormal_muscle_development0.96400173
85MP0002452_abnormal_antigen_presenting0.96273659
86MP0000015_abnormal_ear_pigmentation0.95048956
87MP0005423_abnormal_somatic_nervous0.94579958
88MP0003633_abnormal_nervous_system0.93542361
89MP0005220_abnormal_exocrine_pancreas0.92232177
90MP0002420_abnormal_adaptive_immunity0.92011239
91MP0001819_abnormal_immune_cell0.90491813
92MP0002102_abnormal_ear_morphology0.90489344
93MP0009745_abnormal_behavioral_response0.89961903
94MP0004885_abnormal_endolymph0.89793967
95MP0001177_atelectasis0.89333901
96MP0004883_abnormal_blood_vessel0.88943571
97MP0008995_early_reproductive_senescence0.87658390
98MP0002063_abnormal_learning/memory/cond0.87385997
99MP0000470_abnormal_stomach_morphology0.87316297
100MP0001984_abnormal_olfaction0.86554947
101MP0008872_abnormal_physiological_respon0.85697671
102MP0001502_abnormal_circadian_rhythm0.85524356
103MP0004808_abnormal_hematopoietic_stem0.84889980
104MP0009115_abnormal_fat_cell0.84765048
105MP0004145_abnormal_muscle_electrophysio0.84398984
106MP0001765_abnormal_ion_homeostasis0.82541862
107MP0010234_abnormal_vibrissa_follicle0.80666464
108MP0001346_abnormal_lacrimal_gland0.80545648
109MP0005464_abnormal_platelet_physiology0.80127273
110MP0004185_abnormal_adipocyte_glucose0.79821967
111MP0000613_abnormal_salivary_gland0.79755261
112MP0002572_abnormal_emotion/affect_behav0.79492730
113MP0002419_abnormal_innate_immunity0.79221286
114MP0003724_increased_susceptibility_to0.78017309
115MP0010155_abnormal_intestine_physiology0.77786170
116MP0004134_abnormal_chest_morphology0.77709112
117MP0002108_abnormal_muscle_morphology0.76486516
118MP0002722_abnormal_immune_system0.75228766
119MP0000703_abnormal_thymus_morphology0.75042642
120MP0002090_abnormal_vision0.74903106
121MP0000003_abnormal_adipose_tissue0.73176430
122MP0006082_CNS_inflammation0.72694153
123MP0005375_adipose_tissue_phenotype0.72658593
124MP0003252_abnormal_bile_duct0.72562300
125MP0001944_abnormal_pancreas_morphology0.72410336
126MP0003632_abnormal_nervous_system0.72077895
127MP0008438_abnormal_cutaneous_collagen0.71904313
128MP0000778_abnormal_nervous_system0.71797499
129MP0002398_abnormal_bone_marrow0.71305235
130MP0000465_gastrointestinal_hemorrhage0.70935117
131MP0003656_abnormal_erythrocyte_physiolo0.69604209
132MP0000716_abnormal_immune_system0.69316369
133MP0002163_abnormal_gland_morphology0.67324652
134MP0008874_decreased_physiological_sensi0.67306721
135MP0001440_abnormal_grooming_behavior0.66779412
136MP0004215_abnormal_myocardial_fiber0.66423344
137MP0005666_abnormal_adipose_tissue0.65951436
138MP0005386_behavior/neurological_phenoty0.65402449
139MP0004924_abnormal_behavior0.65402449
140MP0004270_analgesia0.65331910
141MP0009764_decreased_sensitivity_to0.63733556
142MP0004484_altered_response_of0.63156730
143MP0002557_abnormal_social/conspecific_i0.61723933
144MP0000767_abnormal_smooth_muscle0.61666607
145MP0002405_respiratory_system_inflammati0.60355986

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of the fingertips (HP:0001211)4.01641982
2Abnormality of the nasal septum (HP:0000419)3.65996971
3Macroorchidism (HP:0000053)3.65095495
4Pancreatic cysts (HP:0001737)3.63622718
5Hyperventilation (HP:0002883)3.32128573
6Stomach cancer (HP:0012126)3.24883954
7Congenital stationary night blindness (HP:0007642)3.15541739
8Abnormality of the renal cortex (HP:0011035)3.13028514
9Hamartoma of the eye (HP:0010568)3.09176827
10Narrow palate (HP:0000189)3.00327737
11Thyroiditis (HP:0100646)2.82927134
12Aortic aneurysm (HP:0004942)2.69702391
13Conjunctival hamartoma (HP:0100780)2.66784359
14Pancreatic fibrosis (HP:0100732)2.66656657
15Chronic hepatic failure (HP:0100626)2.62190894
16Genetic anticipation (HP:0003743)2.58475097
17Abnormality of the renal medulla (HP:0100957)2.52368947
18Furrowed tongue (HP:0000221)2.50816477
19True hermaphroditism (HP:0010459)2.46997998
20Neoplasm of the tracheobronchial system (HP:0100552)2.46959486
21Truncal obesity (HP:0001956)2.45235305
22Volvulus (HP:0002580)2.45196842
23Attenuation of retinal blood vessels (HP:0007843)2.38323745
24Nephronophthisis (HP:0000090)2.37432278
25Fair hair (HP:0002286)2.36866109
26Decreased circulating renin level (HP:0003351)2.36573640
27Broad metatarsal (HP:0001783)2.34082088
28Action tremor (HP:0002345)2.31439460
29Absent frontal sinuses (HP:0002688)2.25596664
30Abnormality of midbrain morphology (HP:0002418)2.21695857
31Molar tooth sign on MRI (HP:0002419)2.21695857
32Alveolar cell carcinoma (HP:0006519)2.19422578
33T lymphocytopenia (HP:0005403)2.18481607
34Protruding tongue (HP:0010808)2.17478933
35Chronic diarrhea (HP:0002028)2.15168601
36Cerebral aneurysm (HP:0004944)2.13807993
37Aplasia involving bones of the upper limbs (HP:0009823)2.13758885
38Aplasia of the phalanges of the hand (HP:0009802)2.13758885
39Aplasia involving bones of the extremities (HP:0009825)2.13758885
40Febrile seizures (HP:0002373)2.13487839
41Recurrent cutaneous fungal infections (HP:0011370)2.13087607
42Chronic mucocutaneous candidiasis (HP:0002728)2.13087607
43Clumsiness (HP:0002312)2.12851856
44Abnormality of T cell number (HP:0011839)2.12461482
45Tubular atrophy (HP:0000092)2.12446466
46Widely spaced teeth (HP:0000687)2.12439899
47Congenital sensorineural hearing impairment (HP:0008527)2.12414573
48Hamartoma (HP:0010566)2.09283115
49Lip pit (HP:0100267)2.09139288
50Pheochromocytoma (HP:0002666)2.08321000
51Medial flaring of the eyebrow (HP:0010747)2.07880294
52Stomatitis (HP:0010280)2.05886905
53Abnormality of the columella (HP:0009929)2.05823754
54Renal cortical cysts (HP:0000803)2.01310935
552-3 toe syndactyly (HP:0004691)2.00553648
56Papilledema (HP:0001085)2.00502295
57Shallow orbits (HP:0000586)2.00356939
58IgG deficiency (HP:0004315)1.99699937
59Recurrent fungal infections (HP:0002841)1.98493545
60Inability to walk (HP:0002540)1.95959802
61Progressive cerebellar ataxia (HP:0002073)1.94501250
62Dislocated radial head (HP:0003083)1.94160576
63Aqueductal stenosis (HP:0002410)1.93951983
64Meningioma (HP:0002858)1.92734103
65Trigonocephaly (HP:0000243)1.91558078
66Excessive salivation (HP:0003781)1.90316167
67Drooling (HP:0002307)1.90316167
68Autoimmune hemolytic anemia (HP:0001890)1.90188427
69Hypoplastic labia majora (HP:0000059)1.89852267
70Cystic liver disease (HP:0006706)1.89583537
71Abnormality of T cells (HP:0002843)1.88462622
72Aortic dissection (HP:0002647)1.88214951
73Large for gestational age (HP:0001520)1.88133102
74Tented upper lip vermilion (HP:0010804)1.87773516
75Midline defect of the nose (HP:0004122)1.87566259
76Chorioretinal atrophy (HP:0000533)1.87286533
77Poor coordination (HP:0002370)1.87265339
78Hypothermia (HP:0002045)1.87113930
79Curly hair (HP:0002212)1.87083900
80Polydipsia (HP:0001959)1.84492878
81Abnormal drinking behavior (HP:0030082)1.84492878
82Progressive inability to walk (HP:0002505)1.84485594
83Urethral obstruction (HP:0000796)1.84169123
84Long nose (HP:0003189)1.83845020
85Increased corneal curvature (HP:0100692)1.83752252
86Keratoconus (HP:0000563)1.83752252
87Pustule (HP:0200039)1.83402195
88Aplasia/Hypoplasia of the tibia (HP:0005772)1.82952427
89Arterial tortuosity (HP:0005116)1.82277051
90Abnormality of the labia majora (HP:0012881)1.81442538
91Hypoplastic iliac wings (HP:0002866)1.81142574
92Asplenia (HP:0001746)1.79586887
93Blue irides (HP:0000635)1.79201367
94Short chin (HP:0000331)1.78699194
95Hyperkalemia (HP:0002153)1.78312972
96Dysmetric saccades (HP:0000641)1.78206937
97Abnormality of the radial head (HP:0003995)1.78022534
98Decreased central vision (HP:0007663)1.77366773
99Neuroendocrine neoplasm (HP:0100634)1.77215571
100Abnormal delayed hypersensitivity skin test (HP:0002963)1.77049295
101Truncal ataxia (HP:0002078)1.76852532
102Absent speech (HP:0001344)1.76415105
103Recurrent bronchitis (HP:0002837)1.75570868
104Abolished electroretinogram (ERG) (HP:0000550)1.75440136
105Abnormal rod and cone electroretinograms (HP:0008323)1.74798886
106Hemiplegia (HP:0002301)1.74648102
107Agammaglobulinemia (HP:0004432)1.74544992
108Spondylolisthesis (HP:0003302)1.73563698
109Generalized hypopigmentation of hair (HP:0011358)1.73412970
110Acute myeloid leukemia (HP:0004808)1.72600795
111Recurrent viral infections (HP:0004429)1.72544802
112Periodontitis (HP:0000704)1.72361107
113Infantile muscular hypotonia (HP:0008947)1.72326074
114Neoplasm of the adrenal cortex (HP:0100641)1.72191783
115Ureteral stenosis (HP:0000071)1.72119987
116Focal seizures (HP:0007359)1.72023974
117Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)1.72005379
118Ureteral obstruction (HP:0006000)1.71624519
119Submucous cleft hard palate (HP:0000176)1.71575647
120Panhypogammaglobulinemia (HP:0003139)1.70918664
121Disproportionate tall stature (HP:0001519)1.70745518
122Colitis (HP:0002583)1.70528286
123Scanning speech (HP:0002168)1.70298542
124Inflammation of the large intestine (HP:0002037)1.70018746
125Broad-based gait (HP:0002136)1.69590431
126Papillary thyroid carcinoma (HP:0002895)1.69045559
127Aplasia/Hypoplasia of the spleen (HP:0010451)1.68432128
128Gaze-evoked nystagmus (HP:0000640)1.68228721
129Severe combined immunodeficiency (HP:0004430)1.67981781
130Abnormality of the right ventricle (HP:0001707)1.67892255
131Exotropia (HP:0000577)1.67841629
132Osteolytic defects of the hand bones (HP:0009699)1.67404565
133Osteolytic defects of the phalanges of the hand (HP:0009771)1.67404565
134Abnormal hair whorl (HP:0010721)1.67300667
135Abnormality of secondary sexual hair (HP:0009888)1.67039566
136Abnormality of the axillary hair (HP:0100134)1.67039566
137Long eyelashes (HP:0000527)1.66832965
138Depressed nasal tip (HP:0000437)1.66692846
139Urinary bladder sphincter dysfunction (HP:0002839)1.66614266
140Obsessive-compulsive behavior (HP:0000722)1.64946815
141Oligodactyly (hands) (HP:0001180)1.64940860
142Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026)1.63810953
143Short 1st metacarpal (HP:0010034)1.63810953
144Impaired smooth pursuit (HP:0007772)1.63743404
145Open mouth (HP:0000194)1.63141806
146Intestinal atresia (HP:0011100)1.63042853
147Prominent nose (HP:0000448)1.62351693
148Abnormality of eosinophils (HP:0001879)1.62242547
149Vascular tortuosity (HP:0004948)1.61197886
150Abnormal pancreas size (HP:0012094)1.60915984
151Abnormality of incisor morphology (HP:0011063)1.58236139
152Short 4th metacarpal (HP:0010044)1.57809208
153Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.57809208
154Abnormality of the epiphyses of the phalanges of the hand (HP:0005920)1.57593953
155Hematochezia (HP:0002573)1.57047094
156Arterial thrombosis (HP:0004420)1.56404122
157Elfin facies (HP:0004428)1.56164734
158Abnormality of the frontal sinuses (HP:0002687)1.56114979
159Gastrointestinal inflammation (HP:0004386)1.55736212
160Anteriorly placed anus (HP:0001545)1.55305213
161Persistence of primary teeth (HP:0006335)1.55281982
162Chronic otitis media (HP:0000389)1.54590122
163Onion bulb formation (HP:0003383)1.54445179
164Epileptic encephalopathy (HP:0200134)1.53211793
165Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.52889010
166Thick eyebrow (HP:0000574)1.52555702
167Premature skin wrinkling (HP:0100678)1.52248374
168Heterotopia (HP:0002282)1.51591645
169Hip dysplasia (HP:0001385)1.50985072
170Spinal cord lesions (HP:0100561)1.50506303
171Syringomyelia (HP:0003396)1.50506303
172Aneurysm (HP:0002617)1.50504023
173Diplopia (HP:0000651)1.50498527
174Abnormality of binocular vision (HP:0011514)1.50498527
175Abnormality of the humeroradial joint (HP:0100744)1.50476947
176Mitral valve prolapse (HP:0001634)1.50412220
177Hypoplasia of the maxilla (HP:0000327)1.49958859
178Smooth philtrum (HP:0000319)1.49015353

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CAMK1G2.68550823
2CAMK1D2.57980576
3INSRR2.49271483
4ACVR1B2.43643999
5AKT32.41641545
6FGFR22.19768664
7BLK2.16420451
8JAK12.10610340
9TXK2.05362979
10BMPR1B2.03418709
11FGFR32.00023389
12SIK11.90094477
13MAP3K141.77269414
14MAP3K131.76559927
15GRK11.76015661
16WNK11.63860213
17EPHB11.63029580
18ITK1.59391172
19BRD41.59327572
20LATS11.57338910
21MAP3K71.53509547
22EPHA31.52236943
23RIPK11.49931988
24SIK21.49043724
25SGK31.46438523
26JAK31.43912981
27FGFR41.42238267
28MAP4K11.41397685
29FRK1.38346649
30TAOK31.37921944
31EIF2AK31.36910467
32STK391.35673350
33SGK21.33404027
34ADRBK21.33234829
35PDGFRB1.32332429
36PRKCH1.30920352
37PIK3CG1.30762080
38DMPK1.30549778
39TNIK1.28880738
40CDK121.27825708
41MAP4K21.26760304
42TYK21.25497164
43NUAK11.21950100
44ERBB31.18067054
45YES11.16221146
46MARK21.10869359
47PDGFRA1.07803040
48PAK31.06956873
49MAPK131.04578335
50STK31.04023412
51PINK11.03748263
52TGFBR21.03413746
53HCK1.02613899
54PTK2B1.01567627
55RET1.00288801
56NEK91.00100799
57IKBKE0.96684571
58PRKCQ0.96195677
59MAP3K40.93315511
60CAMKK20.91847046
61GRK60.91542988
62TNK20.90967419
63SGK4940.90353133
64SGK2230.90353133
65WNK30.89849743
66RIPK40.88084425
67PTK60.86603547
68PIK3CA0.85895094
69MAPK70.85258935
70NTRK30.83650662
71TTN0.83183615
72PKN10.82885676
73HIPK20.81193320
74WNK40.80338861
75CAMK40.80131766
76CAMKK10.78380901
77SGK10.78210238
78MELK0.77804597
79BTK0.75860116
80LCK0.75804728
81JAK20.75612018
82NTRK20.73959416
83PLK20.73100505
84CDC42BPA0.72521027
85CHUK0.71400157
86BMPR20.70726768
87PRKAA20.70187910
88CAMK10.70018763
89OXSR10.69184862
90MAPKAPK30.69146275
91ADRBK10.68712848
92FES0.68256168
93FYN0.67287100
94CASK0.67162611
95NLK0.67090930
96MKNK20.65990332
97TEC0.65570070
98PDK10.64644388
99MST40.63460981
100LYN0.62514956
101TRPM70.61909056
102ERBB20.58276242
103CSF1R0.58220991
104EEF2K0.58158267
105ZAP700.57176851
106STK110.56961411
107CSK0.56828306
108MAP2K60.55229843
109LMTK20.55013797
110PRKAA10.54955715
111STK380.54912626
112BRSK20.54908333
113PRKCE0.54406719
114MAPK120.54377791
115MTOR0.54185674
116TRIM280.53240017
117MAP3K20.53085928
118SYK0.52775264
119CDK30.52742272
120IGF1R0.52225782
121GRK70.52217606
122PRKD20.51851839
123STK38L0.51811556
124CSNK1A1L0.51487322
125OBSCN0.51317115
126PRKD10.51104253
127TYRO30.49810300
128FGFR10.49665499
129NEK60.49425237
130IKBKB0.49121532
131IRAK10.47837451
132FER0.46916908
133CDK90.46717243
134PRPF4B0.46656090
135CDK50.46017667
136ABL10.45887195
137DAPK20.45656786
138GRK50.45519939
139PKN20.44112982
140FLT30.43817707
141DYRK1A0.43803999
142CDK60.42803705
143INSR0.41481272
144PDPK10.41094695
145KIT0.40199143

Predicted pathways (KEGG)

RankGene SetZ-score
1Circadian rhythm_Homo sapiens_hsa047101.88259369
2Maturity onset diabetes of the young_Homo sapiens_hsa049501.86795667
3Phototransduction_Homo sapiens_hsa047441.51458572
4T cell receptor signaling pathway_Homo sapiens_hsa046601.45881586
5Type II diabetes mellitus_Homo sapiens_hsa049301.42018838
6Primary immunodeficiency_Homo sapiens_hsa053401.41066130
7Phosphatidylinositol signaling system_Homo sapiens_hsa040701.35681014
8Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.31885299
9Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.29894821
10Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.28059321
11Osteoclast differentiation_Homo sapiens_hsa043801.28052281
12Linoleic acid metabolism_Homo sapiens_hsa005911.27110356
13Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.27006718
14Salivary secretion_Homo sapiens_hsa049701.21526635
15Dorso-ventral axis formation_Homo sapiens_hsa043201.21092792
16alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.20382776
17B cell receptor signaling pathway_Homo sapiens_hsa046621.17653026
18Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.16560719
19Olfactory transduction_Homo sapiens_hsa047401.15703142
20Renin secretion_Homo sapiens_hsa049241.15291438
21Long-term potentiation_Homo sapiens_hsa047201.13738793
22Morphine addiction_Homo sapiens_hsa050321.13657863
23Glutamatergic synapse_Homo sapiens_hsa047241.13339461
24Circadian entrainment_Homo sapiens_hsa047131.11981669
25Aldosterone synthesis and secretion_Homo sapiens_hsa049251.11285161
26Gastric acid secretion_Homo sapiens_hsa049711.08712200
27Type I diabetes mellitus_Homo sapiens_hsa049401.07073480
28NF-kappa B signaling pathway_Homo sapiens_hsa040641.06573399
29Nitrogen metabolism_Homo sapiens_hsa009101.06564723
30Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.05719941
31Lysine degradation_Homo sapiens_hsa003101.05631788
32Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.05212683
33Taste transduction_Homo sapiens_hsa047421.04482735
34Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.03124439
35Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.02650812
36Chemokine signaling pathway_Homo sapiens_hsa040620.99023934
37Cholinergic synapse_Homo sapiens_hsa047250.98197739
38Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.97704193
39Nicotine addiction_Homo sapiens_hsa050330.97210421
40cAMP signaling pathway_Homo sapiens_hsa040240.97014923
41Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.96601323
42Choline metabolism in cancer_Homo sapiens_hsa052310.95840755
43Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.94731545
44Measles_Homo sapiens_hsa051620.94674919
45Autoimmune thyroid disease_Homo sapiens_hsa053200.94192994
46Regulation of autophagy_Homo sapiens_hsa041400.93841759
47Oxytocin signaling pathway_Homo sapiens_hsa049210.93227604
48Dilated cardiomyopathy_Homo sapiens_hsa054140.92522885
49Intestinal immune network for IgA production_Homo sapiens_hsa046720.92225878
50Platelet activation_Homo sapiens_hsa046110.92029556
51Amphetamine addiction_Homo sapiens_hsa050310.91763851
52ErbB signaling pathway_Homo sapiens_hsa040120.91419737
53Insulin secretion_Homo sapiens_hsa049110.90499004
54Toxoplasmosis_Homo sapiens_hsa051450.89951383
55Jak-STAT signaling pathway_Homo sapiens_hsa046300.89788535
56Thyroid hormone signaling pathway_Homo sapiens_hsa049190.88580687
57RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.88527554
58Chronic myeloid leukemia_Homo sapiens_hsa052200.87925482
59Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.87653985
60Pancreatic cancer_Homo sapiens_hsa052120.87638175
61GABAergic synapse_Homo sapiens_hsa047270.87117820
62Glioma_Homo sapiens_hsa052140.86471800
63Focal adhesion_Homo sapiens_hsa045100.86418801
64Phospholipase D signaling pathway_Homo sapiens_hsa040720.86248949
65Ether lipid metabolism_Homo sapiens_hsa005650.86049079
66Inositol phosphate metabolism_Homo sapiens_hsa005620.85911615
67Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.85691650
68cGMP-PKG signaling pathway_Homo sapiens_hsa040220.84906915
69Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.84141472
70Toll-like receptor signaling pathway_Homo sapiens_hsa046200.84101874
71Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.83248697
72Insulin resistance_Homo sapiens_hsa049310.83238114
73MAPK signaling pathway_Homo sapiens_hsa040100.83215939
74Leishmaniasis_Homo sapiens_hsa051400.82886954
75Cocaine addiction_Homo sapiens_hsa050300.82307653
76Calcium signaling pathway_Homo sapiens_hsa040200.81795025
77AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.81715623
78GnRH signaling pathway_Homo sapiens_hsa049120.81041350
79Neurotrophin signaling pathway_Homo sapiens_hsa047220.79476015
80Serotonergic synapse_Homo sapiens_hsa047260.79303691
81Steroid hormone biosynthesis_Homo sapiens_hsa001400.79211634
82Prolactin signaling pathway_Homo sapiens_hsa049170.78431250
83Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.77988344
84Transcriptional misregulation in cancer_Homo sapiens_hsa052020.77827961
85Asthma_Homo sapiens_hsa053100.77644461
86Prostate cancer_Homo sapiens_hsa052150.77614540
87Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.77406581
88Carbohydrate digestion and absorption_Homo sapiens_hsa049730.77396150
89Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.76697190
90Rap1 signaling pathway_Homo sapiens_hsa040150.76310744
91Hematopoietic cell lineage_Homo sapiens_hsa046400.76184710
92Dopaminergic synapse_Homo sapiens_hsa047280.76096066
93Proteoglycans in cancer_Homo sapiens_hsa052050.75981462
94Axon guidance_Homo sapiens_hsa043600.75855999
95TNF signaling pathway_Homo sapiens_hsa046680.75185254
96Adherens junction_Homo sapiens_hsa045200.75146548
97Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.74093915
98Endometrial cancer_Homo sapiens_hsa052130.73592301
99Leukocyte transendothelial migration_Homo sapiens_hsa046700.73232838
100ECM-receptor interaction_Homo sapiens_hsa045120.72571386
101Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.72050523
102ABC transporters_Homo sapiens_hsa020100.71433953
103Non-small cell lung cancer_Homo sapiens_hsa052230.71421255
104Vascular smooth muscle contraction_Homo sapiens_hsa042700.71322407
105Regulation of actin cytoskeleton_Homo sapiens_hsa048100.70813755
106Estrogen signaling pathway_Homo sapiens_hsa049150.69814122
107Renal cell carcinoma_Homo sapiens_hsa052110.69566029
108Viral myocarditis_Homo sapiens_hsa054160.69409147
109Pancreatic secretion_Homo sapiens_hsa049720.69376153
110Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.68993684
111Acute myeloid leukemia_Homo sapiens_hsa052210.68855490
112mTOR signaling pathway_Homo sapiens_hsa041500.68675296
113NOD-like receptor signaling pathway_Homo sapiens_hsa046210.68505994
114Long-term depression_Homo sapiens_hsa047300.68391404
115Graft-versus-host disease_Homo sapiens_hsa053320.68015619
116Allograft rejection_Homo sapiens_hsa053300.67833497
117Glycerolipid metabolism_Homo sapiens_hsa005610.67373371
118Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.65634438
119FoxO signaling pathway_Homo sapiens_hsa040680.65403581
120Longevity regulating pathway - mammal_Homo sapiens_hsa042110.64336209
121TGF-beta signaling pathway_Homo sapiens_hsa043500.64232618
122Ovarian steroidogenesis_Homo sapiens_hsa049130.63868787
123Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.63811972
124Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.62947880
125Melanoma_Homo sapiens_hsa052180.61264785
126Caffeine metabolism_Homo sapiens_hsa002320.56804455
127Butanoate metabolism_Homo sapiens_hsa006500.55608259
128Ras signaling pathway_Homo sapiens_hsa040140.55435147
129RNA degradation_Homo sapiens_hsa030180.54781693
130Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.54734906
131Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.54397916
132Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.51644599

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