Rank | Gene Set | Z-score |
---|---|---|
1 | pre-miRNA processing (GO:0031054) | 4.93439850 |
2 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 4.54922722 |
3 | antigen processing and presentation of endogenous antigen (GO:0019883) | 4.33652787 |
4 | negative regulation of histone methylation (GO:0031061) | 4.26020576 |
5 | cytoplasmic mRNA processing body assembly (GO:0033962) | 4.15811932 |
6 | positive regulation of histone deacetylation (GO:0031065) | 4.15492996 |
7 | regulation of B cell receptor signaling pathway (GO:0050855) | 4.12578897 |
8 | mitotic sister chromatid cohesion (GO:0007064) | 4.10282468 |
9 | positive regulation by symbiont of host defense response (GO:0052509) | 3.99842457 |
10 | modulation by symbiont of host defense response (GO:0052031) | 3.99842457 |
11 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 3.99842457 |
12 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 3.99842457 |
13 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 3.99842457 |
14 | modulation by symbiont of host immune response (GO:0052553) | 3.99842457 |
15 | heterochromatin organization (GO:0070828) | 3.94478983 |
16 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 3.88502032 |
17 | histone H3-K4 methylation (GO:0051568) | 3.83247160 |
18 | cellular extravasation (GO:0045123) | 3.70181577 |
19 | negative regulation of mRNA splicing, via spliceosome (GO:0048025) | 3.68953552 |
20 | tolerance induction (GO:0002507) | 3.68855651 |
21 | positive regulation of gamma-delta T cell activation (GO:0046645) | 3.68121306 |
22 | histone H3-K4 trimethylation (GO:0080182) | 3.67706249 |
23 | glucocorticoid receptor signaling pathway (GO:0042921) | 3.66207317 |
24 | nuclear pore complex assembly (GO:0051292) | 3.64282079 |
25 | positive regulation of type I interferon-mediated signaling pathway (GO:0060340) | 3.62805971 |
26 | RNA stabilization (GO:0043489) | 3.60886677 |
27 | mRNA stabilization (GO:0048255) | 3.60886677 |
28 | leukocyte aggregation (GO:0070486) | 3.59728081 |
29 | response to interleukin-15 (GO:0070672) | 3.56923544 |
30 | response to muramyl dipeptide (GO:0032495) | 3.54642180 |
31 | positive regulation of gene expression, epigenetic (GO:0045815) | 3.53571065 |
32 | histone H4-K16 acetylation (GO:0043984) | 3.52477453 |
33 | histone H4-K12 acetylation (GO:0043983) | 3.51256640 |
34 | regulation of gamma-delta T cell differentiation (GO:0045586) | 3.48593734 |
35 | regulation of RNA export from nucleus (GO:0046831) | 3.45507927 |
36 | positive regulation of granulocyte differentiation (GO:0030854) | 3.44518771 |
37 | protein localization to kinetochore (GO:0034501) | 3.43573643 |
38 | B cell receptor signaling pathway (GO:0050853) | 3.40888634 |
39 | DNA unwinding involved in DNA replication (GO:0006268) | 3.34663381 |
40 | intracellular estrogen receptor signaling pathway (GO:0030520) | 3.32769919 |
41 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 3.30926329 |
42 | histone lysine demethylation (GO:0070076) | 3.29673976 |
43 | macrophage activation involved in immune response (GO:0002281) | 3.29396261 |
44 | negative regulation of mRNA processing (GO:0050686) | 3.26479178 |
45 | detection of other organism (GO:0098543) | 3.25486804 |
46 | nuclear pore organization (GO:0006999) | 3.24641908 |
47 | regulation of histone H3-K9 methylation (GO:0051570) | 3.23313823 |
48 | corticosteroid receptor signaling pathway (GO:0031958) | 3.23158315 |
49 | chromatin assembly (GO:0031497) | 3.20485573 |
50 | mitotic chromosome condensation (GO:0007076) | 3.20462339 |
51 | histone H4-K8 acetylation (GO:0043982) | 3.19621329 |
52 | histone H4-K5 acetylation (GO:0043981) | 3.19621329 |
53 | histone demethylation (GO:0016577) | 3.18841845 |
54 | detection of bacterium (GO:0016045) | 3.17860837 |
55 | negative regulation of mRNA metabolic process (GO:1903312) | 3.17591268 |
56 | positive regulation of protein deacetylation (GO:0090312) | 3.17544218 |
57 | negative regulation of RNA splicing (GO:0033119) | 3.17292553 |
58 | regulation of sister chromatid cohesion (GO:0007063) | 3.16638930 |
59 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 3.15676117 |
60 | negative regulation of cell killing (GO:0031342) | 3.15676117 |
61 | mannose metabolic process (GO:0006013) | 3.15668395 |
62 | cellular response to interleukin-15 (GO:0071350) | 3.15497356 |
63 | positive thymic T cell selection (GO:0045059) | 3.14768574 |
64 | regulation of gamma-delta T cell activation (GO:0046643) | 3.12325839 |
65 | regulation of histone H3-K27 methylation (GO:0061085) | 3.10757650 |
66 | response to peptidoglycan (GO:0032494) | 3.10271777 |
67 | activated T cell proliferation (GO:0050798) | 3.06936388 |
68 | DNA duplex unwinding (GO:0032508) | 3.03490385 |
69 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 3.02674223 |
70 | histone lysine methylation (GO:0034968) | 3.01234378 |
71 | negative regulation of T cell mediated immunity (GO:0002710) | 3.00750423 |
72 | NLS-bearing protein import into nucleus (GO:0006607) | 2.99903538 |
73 | DNA geometric change (GO:0032392) | 2.99350121 |
74 | negative regulation of leukocyte mediated immunity (GO:0002704) | 2.98579577 |
75 | nucleosome disassembly (GO:0006337) | 2.98224117 |
76 | protein-DNA complex disassembly (GO:0032986) | 2.98224117 |
77 | histone H2A monoubiquitination (GO:0035518) | 2.98105051 |
78 | 3-UTR-mediated mRNA stabilization (GO:0070935) | 2.97520733 |
79 | histone H3-K9 modification (GO:0061647) | 2.96758047 |
80 | peptidyl-lysine trimethylation (GO:0018023) | 2.93639675 |
81 | sister chromatid segregation (GO:0000819) | 2.93155776 |
82 | dosage compensation (GO:0007549) | 2.92155140 |
83 | germinal center formation (GO:0002467) | 2.91663320 |
84 | protein localization to chromosome, centromeric region (GO:0071459) | 2.90866158 |
85 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 2.90750013 |
86 | response to host (GO:0075136) | 2.90750013 |
87 | response to host defenses (GO:0052200) | 2.90750013 |
88 | mitotic nuclear envelope disassembly (GO:0007077) | 2.90042818 |
89 | regulation of nucleobase-containing compound transport (GO:0032239) | 2.87967445 |
90 | response to host immune response (GO:0052572) | 2.87881038 |
91 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 2.87881038 |
92 | positive regulation of CREB transcription factor activity (GO:0032793) | 2.86620064 |
93 | regulation of interferon-beta biosynthetic process (GO:0045357) | 2.85468327 |
94 | negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665) | 2.85379473 |
95 | negative regulation of amyloid precursor protein catabolic process (GO:1902992) | 2.85050439 |
96 | positive T cell selection (GO:0043368) | 2.84888523 |
97 | regulation of intracellular estrogen receptor signaling pathway (GO:0033146) | 2.84326265 |
98 | regulation of mRNA stability (GO:0043488) | 2.84228730 |
99 | regulation of translational fidelity (GO:0006450) | 2.83871902 |
100 | histone methylation (GO:0016571) | 2.81442887 |
101 | peptidyl-lysine dimethylation (GO:0018027) | 2.81124465 |
102 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 2.80899260 |
103 | negative regulation of T-helper cell differentiation (GO:0045623) | 2.80899260 |
104 | protein demethylation (GO:0006482) | 2.80713566 |
105 | protein dealkylation (GO:0008214) | 2.80713566 |
106 | histone H4 acetylation (GO:0043967) | 2.78855807 |
107 | negative regulation of gene expression, epigenetic (GO:0045814) | 2.77947585 |
108 | negative regulation of histone modification (GO:0031057) | 2.77477712 |
109 | positive regulation of RNA splicing (GO:0033120) | 2.77443726 |
110 | alternative mRNA splicing, via spliceosome (GO:0000380) | 2.77419401 |
111 | regulation of histone H3-K4 methylation (GO:0051569) | 2.76630569 |
112 | neutrophil activation (GO:0042119) | 2.74433347 |
113 | megakaryocyte development (GO:0035855) | 2.72891758 |
114 | regulation of B cell differentiation (GO:0045577) | 2.72806308 |
115 | phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092) | 2.72463382 |
116 | regulation of granulocyte differentiation (GO:0030852) | 2.72252143 |
117 | membrane disassembly (GO:0030397) | 2.71896786 |
118 | nuclear envelope disassembly (GO:0051081) | 2.71896786 |
119 | chromatin silencing (GO:0006342) | 2.71806570 |
120 | mitotic sister chromatid segregation (GO:0000070) | 2.71541312 |
121 | detection of external biotic stimulus (GO:0098581) | 2.71138941 |
122 | gene silencing (GO:0016458) | 2.70570854 |
123 | thymic T cell selection (GO:0045061) | 2.70429910 |
124 | regulation of NFAT protein import into nucleus (GO:0051532) | 2.70204533 |
125 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 2.69900280 |
126 | DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 cla | 2.68741254 |
127 | T cell homeostasis (GO:0043029) | 2.68704405 |
128 | regulation of RNA stability (GO:0043487) | 2.68278872 |
129 | antigen processing and presentation via MHC class Ib (GO:0002475) | 2.65198327 |
130 | neutrophil activation involved in immune response (GO:0002283) | 2.64885323 |
131 | trophectodermal cell differentiation (GO:0001829) | 2.63981539 |
132 | regulation of histone methylation (GO:0031060) | 2.63814177 |
133 | regulation of T cell tolerance induction (GO:0002664) | 2.63807279 |
134 | negative regulation of erythrocyte differentiation (GO:0045647) | 2.63104177 |
135 | positive regulation of Rap GTPase activity (GO:0032854) | 2.61977235 |
136 | negative regulation of cAMP-mediated signaling (GO:0043951) | 2.61796235 |
137 | nuclear-transcribed mRNA poly(A) tail shortening (GO:0000289) | 2.61626990 |
138 | regulation of ARF protein signal transduction (GO:0032012) | 2.61318388 |
139 | histone H3 acetylation (GO:0043966) | 2.60483691 |
140 | negative T cell selection (GO:0043383) | 2.60177376 |
141 | positive regulation of intracellular steroid hormone receptor signaling pathway (GO:0033145) | 2.60121770 |
142 | detection of molecule of bacterial origin (GO:0032490) | 2.59699326 |
143 | negative regulation of chromatin modification (GO:1903309) | 2.59438922 |
144 | T cell selection (GO:0045058) | 2.59268627 |
145 | histone H3-K36 demethylation (GO:0070544) | 2.58425287 |
146 | negative regulation of translation, ncRNA-mediated (GO:0040033) | 2.58403017 |
147 | regulation of translation, ncRNA-mediated (GO:0045974) | 2.58403017 |
148 | negative regulation of translation involved in gene silencing by miRNA (GO:0035278) | 2.58403017 |
149 | positive regulation of chromosome segregation (GO:0051984) | 2.58100376 |
150 | histone acetylation (GO:0016573) | 2.57385255 |
151 | T cell migration (GO:0072678) | 2.56600019 |
152 | peptidyl-lysine methylation (GO:0018022) | 2.56185741 |
153 | positive regulation of mitotic sister chromatid separation (GO:1901970) | 2.55763839 |
154 | positive regulation of mitotic metaphase/anaphase transition (GO:0045842) | 2.55763839 |
155 | positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101) | 2.55763839 |
156 | pore complex assembly (GO:0046931) | 2.55287965 |
157 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 2.54672157 |
158 | regulation of hippo signaling (GO:0035330) | 2.54598015 |
159 | gene silencing by RNA (GO:0031047) | 2.54473711 |
160 | negative thymic T cell selection (GO:0045060) | 2.54230409 |
161 | internal peptidyl-lysine acetylation (GO:0018393) | 2.53730253 |
162 | negative regulation of interleukin-12 production (GO:0032695) | 2.53198191 |
163 | B cell homeostasis (GO:0001782) | 2.52836659 |
164 | response to laminar fluid shear stress (GO:0034616) | 2.51468795 |
165 | histone H3-K9 demethylation (GO:0033169) | 2.50514994 |
166 | regulation of mast cell degranulation (GO:0043304) | 2.50351358 |
167 | regulation of leukocyte degranulation (GO:0043300) | 2.50175853 |
168 | natural killer cell differentiation (GO:0001779) | 2.49528434 |
169 | regulation of tolerance induction (GO:0002643) | 2.48093252 |
170 | neutrophil mediated immunity (GO:0002446) | 2.47907718 |
171 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 2.47682392 |
172 | regulation of DNA damage checkpoint (GO:2000001) | 2.47048630 |
173 | histone mRNA catabolic process (GO:0071044) | 2.46554625 |
174 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 2.45258768 |
175 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 2.45258768 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 7.55619183 |
2 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 4.56707730 |
3 | MYC_22102868_ChIP-Seq_BL_Human | 4.53750694 |
4 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 4.15383232 |
5 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 3.68496183 |
6 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 3.42245050 |
7 | * VDR_21846776_ChIP-Seq_THP-1_Human | 3.02688796 |
8 | TCF7_22412390_ChIP-Seq_EML_Mouse | 2.86214666 |
9 | * KDM2B_26808549_Chip-Seq_DND41_Human | 2.57678777 |
10 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 2.54545634 |
11 | * STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 2.50724820 |
12 | * E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.42783382 |
13 | * KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 2.38399082 |
14 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 2.35489118 |
15 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 2.27499877 |
16 | CIITA_25753668_ChIP-Seq_RAJI_Human | 2.26382780 |
17 | * UTX_26944678_Chip-Seq_JUKART_Human | 2.12626274 |
18 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.04984315 |
19 | MAF_26560356_Chip-Seq_TH1_Human | 2.04831558 |
20 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 2.00180811 |
21 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.99392565 |
22 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.96794394 |
23 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.88271608 |
24 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 1.82077256 |
25 | * KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.80936074 |
26 | * ZFP281_27345836_Chip-Seq_ESCs_Mouse | 1.80630400 |
27 | * ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.79475536 |
28 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.75011974 |
29 | MYB_26560356_Chip-Seq_TH1_Human | 1.74586296 |
30 | * KDM2B_26808549_Chip-Seq_JURKAT_Human | 1.73350120 |
31 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.71777142 |
32 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.71350733 |
33 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.68719491 |
34 | * DMRT1_23473982_ChIP-Seq_TESTES_Mouse | 1.68454697 |
35 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.66993844 |
36 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.64906509 |
37 | * MYB_26560356_Chip-Seq_TH2_Human | 1.62952676 |
38 | * ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.62466843 |
39 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.60576569 |
40 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.57612211 |
41 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.56748610 |
42 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 1.53400970 |
43 | * CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 1.52846404 |
44 | * ZFP281_18757296_ChIP-ChIP_E14_Mouse | 1.51724295 |
45 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.50760501 |
46 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 1.49244491 |
47 | NCOR1_26117541_ChIP-Seq_K562_Human | 1.48654781 |
48 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 1.46554622 |
49 | SALL4_18804426_ChIP-ChIP_MESCs_Mouse | 1.44679644 |
50 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.43476542 |
51 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.42810714 |
52 | * TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.41928594 |
53 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 1.41898221 |
54 | GATA1_19941826_ChIP-Seq_K562_Human | 1.40701063 |
55 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.38797267 |
56 | * STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.38251384 |
57 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.37171852 |
58 | * KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.35343927 |
59 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.34534869 |
60 | TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 1.33904730 |
61 | KDM2B_26808549_Chip-Seq_K562_Human | 1.31824816 |
62 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.31541859 |
63 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.30950619 |
64 | P300_27058665_Chip-Seq_ZR-75-30cells_Human | 1.29672427 |
65 | * BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.29176848 |
66 | * PKCTHETA_26484144_Chip-Seq_BREAST_Human | 1.29160938 |
67 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.28949716 |
68 | MAF_26560356_Chip-Seq_TH2_Human | 1.28870752 |
69 | SPI1_23127762_ChIP-Seq_K562_Human | 1.28439792 |
70 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.28200615 |
71 | * KDM5A_27292631_Chip-Seq_BREAST_Human | 1.27843616 |
72 | * RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.26948042 |
73 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.26106229 |
74 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.25600561 |
75 | * WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 1.22640334 |
76 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.20962879 |
77 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.20535332 |
78 | RUNX1_27514584_Chip-Seq_MCF-7_Human | 1.18240003 |
79 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.17958254 |
80 | * FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human | 1.16954180 |
81 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.16924746 |
82 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.16484860 |
83 | * MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.16162531 |
84 | * CTCF_27219007_Chip-Seq_ERYTHROID_Human | 1.15285586 |
85 | ZIC3_20872845_ChIP-ChIP_MESCs_Mouse | 1.13594700 |
86 | * NANOG_21062744_ChIP-ChIP_HESCs_Human | 1.11611258 |
87 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.11520254 |
88 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.10621070 |
89 | * CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.10573752 |
90 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.08947857 |
91 | * RACK7_27058665_Chip-Seq_MCF-7_Human | 1.08651650 |
92 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 1.08348604 |
93 | * PU_27001747_Chip-Seq_BMDM_Mouse | 1.07896954 |
94 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.05419859 |
95 | * CHD1_26751641_Chip-Seq_LNCaP_Human | 1.05341636 |
96 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.04956273 |
97 | * SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.04861938 |
98 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 1.03621319 |
99 | GATA2_19941826_ChIP-Seq_K562_Human | 1.03490726 |
100 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 1.02497277 |
101 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 1.02497277 |
102 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 1.02497277 |
103 | SMC4_20622854_ChIP-Seq_HELA_Human | 1.01453180 |
104 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.01199272 |
105 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.00307215 |
106 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.00138096 |
107 | NFIB_24661679_ChIP-Seq_LUNG_Mouse | 0.99495624 |
108 | P68_20966046_ChIP-Seq_HELA_Human | 0.98347873 |
109 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.98074247 |
110 | FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human | 0.97839921 |
111 | * CREB1_26743006_Chip-Seq_LNCaP_Human | 0.97311492 |
112 | ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.96966358 |
113 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 0.96799380 |
114 | EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 0.96001819 |
115 | * RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.95759092 |
116 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 0.95480184 |
117 | SPI1_23547873_ChIP-Seq_NB4_Human | 0.94635036 |
118 | * NANOG_18347094_ChIP-ChIP_MESCs_Mouse | 0.94193102 |
119 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 0.93993957 |
120 | * LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 0.93321547 |
121 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 0.93312571 |
122 | CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 0.92952763 |
123 | * CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 0.92843356 |
124 | * SA1_27219007_Chip-Seq_ERYTHROID_Human | 0.92830855 |
125 | BCOR_27268052_Chip-Seq_Bcells_Human | 0.92726138 |
126 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 0.92388760 |
127 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 0.91974289 |
128 | * RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 0.91832299 |
129 | * CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.91243029 |
130 | EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 0.90881419 |
131 | * PU.1_20513432_ChIP-Seq_Bcells_Mouse | 0.90702352 |
132 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 0.89911546 |
133 | ATF3_27146783_Chip-Seq_COLON_Human | 0.89689244 |
134 | * SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.89167707 |
135 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.88522226 |
136 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.88404944 |
137 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 0.87636810 |
138 | * SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 0.87469997 |
139 | GATA1_19941827_ChIP-Seq_MEL86_Mouse | 0.86238556 |
140 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 0.84452420 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003436_decreased_susceptibility_to | 3.67928095 |
2 | MP0005076_abnormal_cell_differentiation | 2.98134881 |
3 | MP0003724_increased_susceptibility_to | 2.90120432 |
4 | MP0001835_abnormal_antigen_presentation | 2.81838340 |
5 | MP0002009_preneoplasia | 2.79810632 |
6 | MP0002396_abnormal_hematopoietic_system | 2.76561389 |
7 | MP0008057_abnormal_DNA_replication | 2.69880780 |
8 | MP0010352_gastrointestinal_tract_polyps | 2.59360775 |
9 | MP0009278_abnormal_bone_marrow | 2.56753743 |
10 | MP0003705_abnormal_hypodermis_morpholog | 2.48186508 |
11 | MP0003111_abnormal_nucleus_morphology | 2.44349190 |
12 | MP0001873_stomach_inflammation | 2.37682219 |
13 | MP0010094_abnormal_chromosome_stability | 2.33011891 |
14 | MP0003077_abnormal_cell_cycle | 2.32224989 |
15 | MP0004808_abnormal_hematopoietic_stem | 2.28751594 |
16 | MP0002419_abnormal_innate_immunity | 2.25452536 |
17 | MP0005000_abnormal_immune_tolerance | 2.18919374 |
18 | MP0004381_abnormal_hair_follicle | 2.13343413 |
19 | MP0005025_abnormal_response_to | 2.11517929 |
20 | MP0003172_abnormal_lysosome_physiology | 2.10749679 |
21 | MP0003300_gastrointestinal_ulcer | 2.09852369 |
22 | MP0000569_abnormal_digit_pigmentation | 2.05032847 |
23 | MP0004947_skin_inflammation | 2.01231474 |
24 | MP0000350_abnormal_cell_proliferation | 1.95683163 |
25 | MP0004957_abnormal_blastocyst_morpholog | 1.95034039 |
26 | MP0003763_abnormal_thymus_physiology | 1.91680275 |
27 | MP0003303_peritoneal_inflammation | 1.89140478 |
28 | MP0003787_abnormal_imprinting | 1.86042304 |
29 | MP0001730_embryonic_growth_arrest | 1.85523700 |
30 | MP0000703_abnormal_thymus_morphology | 1.83922420 |
31 | MP0005397_hematopoietic_system_phenotyp | 1.82671278 |
32 | MP0001545_abnormal_hematopoietic_system | 1.82671278 |
33 | MP0003693_abnormal_embryo_hatching | 1.82657519 |
34 | MP0003984_embryonic_growth_retardation | 1.82251474 |
35 | MP0005310_abnormal_salivary_gland | 1.81171462 |
36 | MP0005380_embryogenesis_phenotype | 1.80777942 |
37 | MP0001672_abnormal_embryogenesis/_devel | 1.80777942 |
38 | MP0002088_abnormal_embryonic_growth/wei | 1.79550143 |
39 | MP0008961_abnormal_basal_metabolism | 1.78546476 |
40 | MP0002398_abnormal_bone_marrow | 1.77588946 |
41 | MP0002086_abnormal_extraembryonic_tissu | 1.72574309 |
42 | MP0003121_genomic_imprinting | 1.72280273 |
43 | MP0010307_abnormal_tumor_latency | 1.69964389 |
44 | MP0002084_abnormal_developmental_patter | 1.68878586 |
45 | MP0002138_abnormal_hepatobiliary_system | 1.66323347 |
46 | MP0004197_abnormal_fetal_growth/weight/ | 1.66031577 |
47 | MP0001849_ear_inflammation | 1.65719284 |
48 | MP0005451_abnormal_body_composition | 1.64116347 |
49 | MP0000685_abnormal_immune_system | 1.60068935 |
50 | MP0001697_abnormal_embryo_size | 1.59977695 |
51 | MP0008260_abnormal_autophagy | 1.59200529 |
52 | MP0003123_paternal_imprinting | 1.59092670 |
53 | MP0002085_abnormal_embryonic_tissue | 1.57286017 |
54 | MP0003866_abnormal_defecation | 1.51485386 |
55 | MP0003183_abnormal_peptide_metabolism | 1.51469503 |
56 | MP0001800_abnormal_humoral_immune | 1.49778823 |
57 | MP0004185_abnormal_adipocyte_glucose | 1.48936016 |
58 | MP0000733_abnormal_muscle_development | 1.46760603 |
59 | MP0003890_abnormal_embryonic-extraembry | 1.46477432 |
60 | MP0002132_abnormal_respiratory_system | 1.46374187 |
61 | MP0001533_abnormal_skeleton_physiology | 1.42704628 |
62 | MP0002653_abnormal_ependyma_morphology | 1.42298499 |
63 | MP0002722_abnormal_immune_system | 1.41172119 |
64 | MP0000689_abnormal_spleen_morphology | 1.38724643 |
65 | MP0004264_abnormal_extraembryonic_tissu | 1.35146113 |
66 | MP0002080_prenatal_lethality | 1.34487408 |
67 | MP0002925_abnormal_cardiovascular_devel | 1.34290320 |
68 | MP0009785_altered_susceptibility_to | 1.32915972 |
69 | MP0001915_intracranial_hemorrhage | 1.32091901 |
70 | MP0004858_abnormal_nervous_system | 1.30972512 |
71 | MP0009703_decreased_birth_body | 1.28558192 |
72 | MP0003567_abnormal_fetal_cardiomyocyte | 1.28007386 |
73 | MP0003566_abnormal_cell_adhesion | 1.24773449 |
74 | MP0000716_abnormal_immune_system | 1.24274322 |
75 | MP0001851_eye_inflammation | 1.24117709 |
76 | MP0008877_abnormal_DNA_methylation | 1.23579667 |
77 | MP0009672_abnormal_birth_weight | 1.23389160 |
78 | MP0002166_altered_tumor_susceptibility | 1.21457398 |
79 | MP0003045_fibrosis | 1.20641952 |
80 | MP0000490_abnormal_crypts_of | 1.20605591 |
81 | MP0005464_abnormal_platelet_physiology | 1.20488237 |
82 | MP0002998_abnormal_bone_remodeling | 1.18951165 |
83 | MP0002019_abnormal_tumor_incidence | 1.18917297 |
84 | MP0001790_abnormal_immune_system | 1.18355979 |
85 | MP0005387_immune_system_phenotype | 1.18355979 |
86 | MP0003119_abnormal_digestive_system | 1.17260032 |
87 | MP0009333_abnormal_splenocyte_physiolog | 1.16106705 |
88 | MP0002429_abnormal_blood_cell | 1.14928722 |
89 | MP0001845_abnormal_inflammatory_respons | 1.14471652 |
90 | MP0010630_abnormal_cardiac_muscle | 1.13988309 |
91 | MP0002877_abnormal_melanocyte_morpholog | 1.12527278 |
92 | MP0003935_abnormal_craniofacial_develop | 1.12212918 |
93 | MP0000428_abnormal_craniofacial_morphol | 1.09285731 |
94 | MP0003191_abnormal_cellular_cholesterol | 1.07624489 |
95 | MP0005409_darkened_coat_color | 1.06927785 |
96 | MP0008770_decreased_survivor_rate | 1.06880633 |
97 | MP0000266_abnormal_heart_morphology | 1.06716945 |
98 | MP0000313_abnormal_cell_death | 1.06682519 |
99 | MP0008007_abnormal_cellular_replicative | 1.06426533 |
100 | MP0002148_abnormal_hypersensitivity_rea | 1.05693728 |
101 | MP0002452_abnormal_antigen_presenting | 1.04246052 |
102 | MP0002420_abnormal_adaptive_immunity | 1.03196774 |
103 | MP0003091_abnormal_cell_migration | 1.02213932 |
104 | MP0004130_abnormal_muscle_cell | 1.01071674 |
105 | MP0001819_abnormal_immune_cell | 1.01068133 |
106 | MP0002933_joint_inflammation | 0.99989877 |
107 | MP0006054_spinal_hemorrhage | 0.98494127 |
108 | MP0005023_abnormal_wound_healing | 0.98382696 |
109 | MP0002405_respiratory_system_inflammati | 0.97248484 |
110 | MP0001293_anophthalmia | 0.96321825 |
111 | MP0002092_abnormal_eye_morphology | 0.92554778 |
112 | MP0001784_abnormal_fluid_regulation | 0.91362523 |
113 | MP0003115_abnormal_respiratory_system | 0.90688936 |
114 | MP0000015_abnormal_ear_pigmentation | 0.90533571 |
115 | MP0005075_abnormal_melanosome_morpholog | 0.90327337 |
116 | MP0010234_abnormal_vibrissa_follicle | 0.89756987 |
117 | MP0008058_abnormal_DNA_repair | 0.89582423 |
118 | MP0001853_heart_inflammation | 0.89440235 |
119 | MP0002277_abnormal_respiratory_mucosa | 0.87483661 |
120 | MP0009115_abnormal_fat_cell | 0.87293146 |
121 | MP0000858_altered_metastatic_potential | 0.86990744 |
122 | MP0002723_abnormal_immune_serum | 0.85688626 |
123 | MP0010155_abnormal_intestine_physiology | 0.85054641 |
124 | MP0005621_abnormal_cell_physiology | 0.84572701 |
125 | MP0002006_tumorigenesis | 0.84469884 |
126 | MP0005666_abnormal_adipose_tissue | 0.84033021 |
127 | MP0001348_abnormal_lacrimal_gland | 0.83909773 |
128 | MP0009053_abnormal_anal_canal | 0.83381954 |
129 | MP0003943_abnormal_hepatobiliary_system | 0.83363952 |
130 | MP0008469_abnormal_protein_level | 0.82398751 |
131 | MP0002928_abnormal_bile_duct | 0.81556673 |
132 | MP0000432_abnormal_head_morphology | 0.81166299 |
133 | MP0000537_abnormal_urethra_morphology | 0.78204574 |
134 | MP0003122_maternal_imprinting | 0.76651756 |
135 | MP0004883_abnormal_blood_vessel | 0.76459811 |
136 | MP0003828_pulmonary_edema | 0.76025046 |
137 | MP0000767_abnormal_smooth_muscle | 0.75048339 |
138 | MP0005671_abnormal_response_to | 0.74943130 |
139 | MP0000470_abnormal_stomach_morphology | 0.74189207 |
140 | MP0000477_abnormal_intestine_morphology | 0.73585705 |
141 | MP0006082_CNS_inflammation | 0.73140120 |
142 | MP0005083_abnormal_biliary_tract | 0.72061807 |
143 | MP0004233_abnormal_muscle_weight | 0.71817999 |
144 | MP0010368_abnormal_lymphatic_system | 0.71533400 |
145 | MP0000465_gastrointestinal_hemorrhage | 0.69178139 |
146 | MP0002249_abnormal_larynx_morphology | 0.67415599 |
147 | MP0001986_abnormal_taste_sensitivity | 0.65226988 |
148 | MP0004510_myositis | 0.64153587 |
149 | MP0002822_catalepsy | 0.63370731 |
150 | MP0001663_abnormal_digestive_system | 0.62973036 |
151 | MP0003656_abnormal_erythrocyte_physiolo | 0.60465683 |
152 | MP0005390_skeleton_phenotype | 0.59416731 |
153 | MP0005375_adipose_tissue_phenotype | 0.56558603 |
154 | MP0008995_early_reproductive_senescence | 0.56184182 |
155 | MP0005220_abnormal_exocrine_pancreas | 0.55225820 |
156 | MP0009931_abnormal_skin_appearance | 0.55201150 |
157 | MP0002970_abnormal_white_adipose | 0.54877579 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Abnormality of the fingertips (HP:0001211) | 4.83648506 |
2 | Eczematoid dermatitis (HP:0000976) | 4.71337977 |
3 | Recurrent abscess formation (HP:0002722) | 3.71174992 |
4 | Obstructive sleep apnea (HP:0002870) | 3.65489396 |
5 | Recurrent bacterial skin infections (HP:0005406) | 3.60703668 |
6 | Recurrent fungal infections (HP:0002841) | 3.51859380 |
7 | Myositis (HP:0100614) | 3.50156937 |
8 | Hyperacusis (HP:0010780) | 3.37890259 |
9 | Stomatitis (HP:0010280) | 3.29137454 |
10 | Elevated erythrocyte sedimentation rate (HP:0003565) | 3.27352499 |
11 | Increased IgE level (HP:0003212) | 3.12972864 |
12 | Short 4th metacarpal (HP:0010044) | 3.08563607 |
13 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 3.08563607 |
14 | Ependymoma (HP:0002888) | 3.02968501 |
15 | Orchitis (HP:0100796) | 2.97855042 |
16 | Gastrointestinal infarctions (HP:0005244) | 2.94810277 |
17 | Spontaneous hematomas (HP:0007420) | 2.93706683 |
18 | Long eyelashes (HP:0000527) | 2.93147398 |
19 | Mediastinal lymphadenopathy (HP:0100721) | 2.93111414 |
20 | Abnormality of macrophages (HP:0004311) | 2.92435326 |
21 | Genetic anticipation (HP:0003743) | 2.89846849 |
22 | Meningitis (HP:0001287) | 2.89362929 |
23 | Volvulus (HP:0002580) | 2.86729592 |
24 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.86718401 |
25 | Recurrent cutaneous fungal infections (HP:0011370) | 2.86718401 |
26 | Optic neuritis (HP:0100653) | 2.79780859 |
27 | Retrobulbar optic neuritis (HP:0100654) | 2.79780859 |
28 | Gingivitis (HP:0000230) | 2.75031156 |
29 | Macroorchidism (HP:0000053) | 2.73164660 |
30 | Prolonged bleeding time (HP:0003010) | 2.72190832 |
31 | Abnormality of the columella (HP:0009929) | 2.69389429 |
32 | Pustule (HP:0200039) | 2.66146712 |
33 | Papilledema (HP:0001085) | 2.65572953 |
34 | Hypochromic microcytic anemia (HP:0004840) | 2.61932270 |
35 | Chest pain (HP:0100749) | 2.60458049 |
36 | Neonatal hypoglycemia (HP:0001998) | 2.59487452 |
37 | Hypochromic anemia (HP:0001931) | 2.57837400 |
38 | Abnormality of the astrocytes (HP:0100707) | 2.55733808 |
39 | Astrocytoma (HP:0009592) | 2.55733808 |
40 | Increased nuchal translucency (HP:0010880) | 2.53975466 |
41 | Broad face (HP:0000283) | 2.53390550 |
42 | Cerebral aneurysm (HP:0004944) | 2.53088777 |
43 | Recurrent skin infections (HP:0001581) | 2.51274131 |
44 | Chronic obstructive pulmonary disease (HP:0006510) | 2.50964544 |
45 | Obstructive lung disease (HP:0006536) | 2.50964544 |
46 | Slow saccadic eye movements (HP:0000514) | 2.47976992 |
47 | Supernumerary ribs (HP:0005815) | 2.47883330 |
48 | Basal cell carcinoma (HP:0002671) | 2.45955939 |
49 | Neoplasm of the oral cavity (HP:0100649) | 2.45583194 |
50 | Vasculitis (HP:0002633) | 2.44101719 |
51 | Renal duplication (HP:0000075) | 2.39011044 |
52 | Encephalitis (HP:0002383) | 2.37066358 |
53 | Trigonocephaly (HP:0000243) | 2.36494154 |
54 | Narrow palate (HP:0000189) | 2.34286396 |
55 | Elfin facies (HP:0004428) | 2.34165144 |
56 | Recurrent gram-negative bacterial infections (HP:0005420) | 2.33911217 |
57 | Abnormality of the 4th metacarpal (HP:0010012) | 2.29163727 |
58 | Renovascular hypertension (HP:0100817) | 2.27540496 |
59 | Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204) | 2.27433057 |
60 | Sparse lateral eyebrow (HP:0005338) | 2.24777295 |
61 | Prominent nose (HP:0000448) | 2.24501608 |
62 | Heterotopia (HP:0002282) | 2.21980440 |
63 | Recurrent viral infections (HP:0004429) | 2.21213560 |
64 | Medulloblastoma (HP:0002885) | 2.20470350 |
65 | Abnormality of T cells (HP:0002843) | 2.18393169 |
66 | Neoplasm of striated muscle (HP:0009728) | 2.18079842 |
67 | Shallow orbits (HP:0000586) | 2.16053567 |
68 | Ulnar bowing (HP:0003031) | 2.14731675 |
69 | Acute lymphatic leukemia (HP:0006721) | 2.14148972 |
70 | Subacute progressive viral hepatitis (HP:0006572) | 2.13431300 |
71 | Syringomyelia (HP:0003396) | 2.12345401 |
72 | Spinal cord lesions (HP:0100561) | 2.12345401 |
73 | Viral hepatitis (HP:0006562) | 2.11104514 |
74 | Supernumerary bones of the axial skeleton (HP:0009144) | 2.10568322 |
75 | Skin tags (HP:0010609) | 2.10348266 |
76 | Arterial thrombosis (HP:0004420) | 2.08870814 |
77 | Obsessive-compulsive behavior (HP:0000722) | 2.04695580 |
78 | Vertebral arch anomaly (HP:0008438) | 2.03509646 |
79 | Persistence of primary teeth (HP:0006335) | 2.03312336 |
80 | Broad palm (HP:0001169) | 2.02141167 |
81 | Rectal prolapse (HP:0002035) | 2.02110254 |
82 | Epistaxis (HP:0000421) | 2.02049824 |
83 | Cellulitis (HP:0100658) | 2.00824739 |
84 | Hemoptysis (HP:0002105) | 2.00720221 |
85 | Lymphopenia (HP:0001888) | 1.99768911 |
86 | Urethral obstruction (HP:0000796) | 1.98757095 |
87 | Overriding aorta (HP:0002623) | 1.97471094 |
88 | Hematochezia (HP:0002573) | 1.96561875 |
89 | Malignant gastrointestinal tract tumors (HP:0006749) | 1.95531489 |
90 | Gastrointestinal carcinoma (HP:0002672) | 1.95531489 |
91 | T lymphocytopenia (HP:0005403) | 1.95352485 |
92 | Segmental peripheral demyelination/remyelination (HP:0003481) | 1.95009485 |
93 | Leukocytosis (HP:0001974) | 1.94478067 |
94 | Truncal obesity (HP:0001956) | 1.94098978 |
95 | Increased density of long bones (HP:0006392) | 1.92817116 |
96 | Germ cell neoplasia (HP:0100728) | 1.91391427 |
97 | Abnormality of the radial head (HP:0003995) | 1.89430437 |
98 | High pitched voice (HP:0001620) | 1.89329679 |
99 | Deviation of the thumb (HP:0009603) | 1.89275794 |
100 | Acute myeloid leukemia (HP:0004808) | 1.88969042 |
101 | Broad thumb (HP:0011304) | 1.88589413 |
102 | Glioma (HP:0009733) | 1.88037896 |
103 | Bowel diverticulosis (HP:0005222) | 1.87553724 |
104 | Proximal placement of thumb (HP:0009623) | 1.87455815 |
105 | Colitis (HP:0002583) | 1.87269669 |
106 | Anal stenosis (HP:0002025) | 1.86593521 |
107 | Abnormality of the lower motor neuron (HP:0002366) | 1.86255268 |
108 | Deep palmar crease (HP:0006191) | 1.86032568 |
109 | Dysmetric saccades (HP:0000641) | 1.86014633 |
110 | Granulocytopenia (HP:0001913) | 1.85978238 |
111 | Urticaria (HP:0001025) | 1.85876736 |
112 | Gastrointestinal inflammation (HP:0004386) | 1.85445160 |
113 | Keratoconjunctivitis sicca (HP:0001097) | 1.84382783 |
114 | Pulmonary infiltrates (HP:0002113) | 1.83550323 |
115 | Pointed chin (HP:0000307) | 1.83403761 |
116 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 1.82983172 |
117 | Clumsiness (HP:0002312) | 1.82301808 |
118 | Verrucae (HP:0200043) | 1.82267491 |
119 | Papilloma (HP:0012740) | 1.82267491 |
120 | Panhypogammaglobulinemia (HP:0003139) | 1.82003591 |
121 | Neoplasm of the heart (HP:0100544) | 1.81739393 |
122 | Short 5th finger (HP:0009237) | 1.81356982 |
123 | Ectopic kidney (HP:0000086) | 1.81326212 |
124 | Insomnia (HP:0100785) | 1.81205433 |
125 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 1.80691485 |
126 | Abnormality of T cell physiology (HP:0011840) | 1.79749060 |
127 | Sandal gap (HP:0001852) | 1.78323014 |
128 | Metaphyseal cupping (HP:0003021) | 1.76901252 |
129 | Deep philtrum (HP:0002002) | 1.76502539 |
130 | Short phalanx of the thumb (HP:0009660) | 1.76285248 |
131 | Rhabdomyosarcoma (HP:0002859) | 1.75647662 |
132 | Cutis marmorata (HP:0000965) | 1.74930777 |
133 | Recurrent bronchitis (HP:0002837) | 1.74758824 |
134 | Abnormality of the diencephalon (HP:0010662) | 1.74141178 |
135 | Hypoplasia of the maxilla (HP:0000327) | 1.73987641 |
136 | Inflammation of the large intestine (HP:0002037) | 1.73617727 |
137 | Abnormality of T cell number (HP:0011839) | 1.73576654 |
138 | Intestinal fistula (HP:0100819) | 1.72873522 |
139 | Gingival bleeding (HP:0000225) | 1.72610776 |
140 | Osteomyelitis (HP:0002754) | 1.71977981 |
141 | Abnormality of the distal phalanx of the thumb (HP:0009617) | 1.71547851 |
142 | Long palpebral fissure (HP:0000637) | 1.71464042 |
143 | Absent frontal sinuses (HP:0002688) | 1.71224013 |
144 | Facial hemangioma (HP:0000329) | 1.70995383 |
145 | Abnormality of the nasal septum (HP:0000419) | 1.70542608 |
146 | Tented upper lip vermilion (HP:0010804) | 1.70461841 |
147 | Microcytic anemia (HP:0001935) | 1.69754123 |
148 | Pulmonary embolism (HP:0002204) | 1.69577828 |
149 | Genu recurvatum (HP:0002816) | 1.68840288 |
150 | Onion bulb formation (HP:0003383) | 1.68779678 |
151 | Episodic fever (HP:0001954) | 1.68555802 |
152 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 1.68273152 |
153 | Keratoconjunctivitis (HP:0001096) | 1.68215909 |
154 | Limited elbow extension (HP:0001377) | 1.68003758 |
155 | Pseudobulbar signs (HP:0002200) | 1.67545289 |
156 | Cafe-au-lait spot (HP:0000957) | 1.67383159 |
157 | Mitral valve prolapse (HP:0001634) | 1.67339934 |
158 | Preauricular skin tag (HP:0000384) | 1.66600136 |
159 | Hereditary nonpolyposis colorectal carcinoma (HP:0006716) | 1.66330391 |
160 | Stomach cancer (HP:0012126) | 1.66316714 |
161 | Nasal polyposis (HP:0100582) | 1.65887371 |
162 | Lip pit (HP:0100267) | 1.65524719 |
163 | Abnormality of the intervertebral disk (HP:0005108) | 1.65504329 |
164 | Spondylolisthesis (HP:0003302) | 1.65200493 |
165 | Agammaglobulinemia (HP:0004432) | 1.64370162 |
166 | Abnormal number of incisors (HP:0011064) | 1.63212354 |
167 | Dislocated radial head (HP:0003083) | 1.62895865 |
168 | Aplasia/Hypoplasia of the 5th finger (HP:0006262) | 1.62412125 |
169 | Enlarged penis (HP:0000040) | 1.62303241 |
170 | Autoimmune thrombocytopenia (HP:0001973) | 1.62234768 |
171 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 1.62066243 |
172 | Increased cerebral lipofuscin (HP:0011813) | 1.61638666 |
173 | Rib fusion (HP:0000902) | 1.61474937 |
174 | Ankyloglossia (HP:0010296) | 1.61297694 |
175 | Gastrointestinal stroma tumor (HP:0100723) | 1.61234913 |
176 | Skull defect (HP:0001362) | 1.60931553 |
Rank | Gene Set | Z-score |
---|---|---|
1 | CDK12 | 5.62972720 |
2 | MAP3K10 | 3.70580771 |
3 | EEF2K | 3.36072451 |
4 | TRIB3 | 3.06602490 |
5 | RIPK4 | 2.89052089 |
6 | MAP4K1 | 2.76556126 |
7 | PRPF4B | 2.58616234 |
8 | PKN2 | 2.37253695 |
9 | CDC7 | 2.22807231 |
10 | BRD4 | 2.20002423 |
11 | NEK2 | 2.16800028 |
12 | SIK2 | 1.84338573 |
13 | ERN1 | 1.83445434 |
14 | STK10 | 1.80749994 |
15 | SMG1 | 1.71595653 |
16 | IRAK4 | 1.70874413 |
17 | AKT3 | 1.69668383 |
18 | ICK | 1.67339168 |
19 | FES | 1.61591375 |
20 | BLK | 1.60420709 |
21 | GRK6 | 1.58020972 |
22 | CDK4 | 1.55345109 |
23 | EPHB1 | 1.49092818 |
24 | SIK3 | 1.47654632 |
25 | ALK | 1.44330401 |
26 | JAK3 | 1.41423081 |
27 | MTOR | 1.35667655 |
28 | PTK6 | 1.34728358 |
29 | CAMK1G | 1.33352119 |
30 | RIPK1 | 1.32055446 |
31 | CDK6 | 1.26194289 |
32 | MAP3K7 | 1.26120266 |
33 | CAMK1D | 1.23017641 |
34 | TYRO3 | 1.20545417 |
35 | DMPK | 1.19770356 |
36 | TAOK1 | 1.16902801 |
37 | NLK | 1.14288905 |
38 | TXK | 1.13003767 |
39 | MARK2 | 1.08814769 |
40 | CSF1R | 1.08674214 |
41 | LATS1 | 1.08662193 |
42 | PDGFRA | 1.06895650 |
43 | IKBKE | 1.06741716 |
44 | SIK1 | 1.05676110 |
45 | BTK | 1.04433121 |
46 | HIPK2 | 1.03593808 |
47 | MAP3K14 | 1.02297364 |
48 | MELK | 1.01634092 |
49 | PRKD2 | 1.01191073 |
50 | CDK7 | 1.00823853 |
51 | SGK2 | 0.98590604 |
52 | CDK9 | 0.98442758 |
53 | MAP3K3 | 0.97448376 |
54 | LRRK2 | 0.94253237 |
55 | TTN | 0.91669242 |
56 | CHEK1 | 0.91242724 |
57 | RPS6KA4 | 0.91125150 |
58 | BMX | 0.90802230 |
59 | YES1 | 0.87963876 |
60 | KSR2 | 0.87851466 |
61 | ATR | 0.87763643 |
62 | CAMKK1 | 0.85169682 |
63 | STK38 | 0.84623628 |
64 | TAOK3 | 0.83453084 |
65 | TEC | 0.82640872 |
66 | MAP3K8 | 0.82448940 |
67 | TTK | 0.81728842 |
68 | RPS6KB2 | 0.80923792 |
69 | FGFR3 | 0.80701179 |
70 | IRAK1 | 0.79675214 |
71 | FLT3 | 0.79312153 |
72 | ZAP70 | 0.79196564 |
73 | MAP3K6 | 0.78348352 |
74 | PIM1 | 0.78015803 |
75 | CDK2 | 0.77784852 |
76 | CSK | 0.77123944 |
77 | MAP3K1 | 0.75423909 |
78 | PASK | 0.74611940 |
79 | STK4 | 0.74539726 |
80 | PDK1 | 0.74362452 |
81 | MAPK7 | 0.73872951 |
82 | PDGFRB | 0.73431010 |
83 | LYN | 0.72702814 |
84 | CHEK2 | 0.72146257 |
85 | TYK2 | 0.71942159 |
86 | SCYL2 | 0.70636791 |
87 | CHUK | 0.70471884 |
88 | ATM | 0.70225795 |
89 | STK3 | 0.69759879 |
90 | ITK | 0.69717442 |
91 | PRKD3 | 0.67591632 |
92 | PRKCH | 0.67466760 |
93 | HCK | 0.67101786 |
94 | CLK1 | 0.66776255 |
95 | JAK1 | 0.66750446 |
96 | TBK1 | 0.66223736 |
97 | MARK3 | 0.65903047 |
98 | SGK3 | 0.65755167 |
99 | IRAK2 | 0.62186178 |
100 | CDC42BPA | 0.61493918 |
101 | MAPK12 | 0.61286886 |
102 | WNK1 | 0.60375819 |
103 | PDPK1 | 0.58602847 |
104 | SGK223 | 0.58356347 |
105 | SGK494 | 0.58356347 |
106 | SYK | 0.56230191 |
107 | IKBKB | 0.56009884 |
108 | FRK | 0.55643248 |
109 | CAMK4 | 0.53955113 |
110 | FGR | 0.53784924 |
111 | MAP2K2 | 0.53365418 |
112 | PAK4 | 0.52491052 |
113 | JAK2 | 0.52174138 |
114 | FGFR4 | 0.51933294 |
115 | RPS6KC1 | 0.50845976 |
116 | RPS6KL1 | 0.50845976 |
117 | PAK2 | 0.50739507 |
118 | LCK | 0.50230468 |
119 | EPHA3 | 0.49411990 |
120 | TGFBR2 | 0.49269377 |
121 | * MAPK14 | 0.48785550 |
122 | MAPK1 | 0.47837584 |
123 | MATK | 0.47630411 |
124 | MAP3K13 | 0.47452756 |
125 | STK11 | 0.46526133 |
126 | TGFBR1 | 0.46519685 |
127 | RPS6KA1 | 0.46347786 |
128 | KIT | 0.46101022 |
129 | PRKAA2 | 0.45950016 |
130 | TNK2 | 0.45909740 |
131 | * CDK1 | 0.45384420 |
132 | RET | 0.45262429 |
133 | MKNK2 | 0.45157263 |
134 | RPS6KA6 | 0.44319226 |
135 | MAPK11 | 0.42431311 |
136 | AKT1 | 0.41924475 |
137 | PTK2 | 0.41258197 |
138 | RPS6KA2 | 0.39589885 |
139 | * GSK3B | 0.38871361 |
140 | MAP2K3 | 0.38699636 |
141 | MAPK10 | 0.38432065 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.99668557 |
2 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.92593678 |
3 | Lysine degradation_Homo sapiens_hsa00310 | 1.91949768 |
4 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.91403492 |
5 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.87721733 |
6 | mTOR signaling pathway_Homo sapiens_hsa04150 | 1.72996939 |
7 | Notch signaling pathway_Homo sapiens_hsa04330 | 1.65596990 |
8 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 1.57519710 |
9 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.54083193 |
10 | Cell cycle_Homo sapiens_hsa04110 | 1.53279323 |
11 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 1.46095864 |
12 | Colorectal cancer_Homo sapiens_hsa05210 | 1.45401064 |
13 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.39641957 |
14 | Pancreatic cancer_Homo sapiens_hsa05212 | 1.39422754 |
15 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.37946938 |
16 | Spliceosome_Homo sapiens_hsa03040 | 1.36894216 |
17 | RNA transport_Homo sapiens_hsa03013 | 1.36885049 |
18 | Adherens junction_Homo sapiens_hsa04520 | 1.34433084 |
19 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 1.34097491 |
20 | Mismatch repair_Homo sapiens_hsa03430 | 1.33336568 |
21 | DNA replication_Homo sapiens_hsa03030 | 1.32599757 |
22 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.32191321 |
23 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 1.32107155 |
24 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.30016221 |
25 | Small cell lung cancer_Homo sapiens_hsa05222 | 1.29287958 |
26 | Base excision repair_Homo sapiens_hsa03410 | 1.26533424 |
27 | Endometrial cancer_Homo sapiens_hsa05213 | 1.25725967 |
28 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.24647544 |
29 | HTLV-I infection_Homo sapiens_hsa05166 | 1.23647937 |
30 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.23354768 |
31 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 1.22641988 |
32 | Hepatitis C_Homo sapiens_hsa05160 | 1.20376086 |
33 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 1.17844602 |
34 | Allograft rejection_Homo sapiens_hsa05330 | 1.16513367 |
35 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.16373596 |
36 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.15100998 |
37 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.14828541 |
38 | Tuberculosis_Homo sapiens_hsa05152 | 1.14355022 |
39 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.13849043 |
40 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.10090144 |
41 | Osteoclast differentiation_Homo sapiens_hsa04380 | 1.09714740 |
42 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 1.05863741 |
43 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 1.05394437 |
44 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 1.05182788 |
45 | Glioma_Homo sapiens_hsa05214 | 1.05061432 |
46 | Hepatitis B_Homo sapiens_hsa05161 | 1.04338256 |
47 | VEGF signaling pathway_Homo sapiens_hsa04370 | 1.03779516 |
48 | Prostate cancer_Homo sapiens_hsa05215 | 1.03198427 |
49 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.03189693 |
50 | Other glycan degradation_Homo sapiens_hsa00511 | 1.00950715 |
51 | Viral myocarditis_Homo sapiens_hsa05416 | 1.00577038 |
52 | Measles_Homo sapiens_hsa05162 | 1.00026029 |
53 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.99174533 |
54 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.98891918 |
55 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.98846053 |
56 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.97932284 |
57 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.97442459 |
58 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.97441348 |
59 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.95289990 |
60 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.95111041 |
61 | Platelet activation_Homo sapiens_hsa04611 | 0.94800132 |
62 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.94647632 |
63 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.93115218 |
64 | Insulin resistance_Homo sapiens_hsa04931 | 0.92154123 |
65 | Thyroid cancer_Homo sapiens_hsa05216 | 0.91746726 |
66 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.89376994 |
67 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.88839987 |
68 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.88471473 |
69 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.87343071 |
70 | Leishmaniasis_Homo sapiens_hsa05140 | 0.87108966 |
71 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.86676108 |
72 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.86219502 |
73 | Pathways in cancer_Homo sapiens_hsa05200 | 0.85956348 |
74 | RNA degradation_Homo sapiens_hsa03018 | 0.85376927 |
75 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.85218964 |
76 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.84614070 |
77 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.84513650 |
78 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.83033247 |
79 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.82301336 |
80 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.82152685 |
81 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.81022832 |
82 | Focal adhesion_Homo sapiens_hsa04510 | 0.81017433 |
83 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.80449433 |
84 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.79932640 |
85 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.79741864 |
86 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.78847703 |
87 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.77878223 |
88 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.77595974 |
89 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.77441721 |
90 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.77164962 |
91 | Influenza A_Homo sapiens_hsa05164 | 0.76718100 |
92 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.76576436 |
93 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.76431483 |
94 | Shigellosis_Homo sapiens_hsa05131 | 0.76329418 |
95 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.74742260 |
96 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.73975615 |
97 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.71598212 |
98 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.71231569 |
99 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.70990926 |
100 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.70330533 |
101 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.70185629 |
102 | Bladder cancer_Homo sapiens_hsa05219 | 0.70175000 |
103 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.68796568 |
104 | Malaria_Homo sapiens_hsa05144 | 0.68389468 |
105 | Apoptosis_Homo sapiens_hsa04210 | 0.67726022 |
106 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.67309780 |
107 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.66922100 |
108 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.66543157 |
109 | Endocytosis_Homo sapiens_hsa04144 | 0.66402062 |
110 | Long-term potentiation_Homo sapiens_hsa04720 | 0.66051998 |
111 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.66019987 |
112 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.64583049 |
113 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.63292461 |
114 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.63178653 |
115 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.62997510 |
116 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.62832867 |
117 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.61145241 |
118 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.60076512 |
119 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.59784761 |
120 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.59226135 |
121 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.56954183 |
122 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.54518648 |
123 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.53663670 |
124 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.52707862 |
125 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.49598389 |
126 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.46408136 |
127 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.46336785 |