PHF19

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA unwinding involved in DNA replication (GO:0006268)5.55643807
2protein localization to kinetochore (GO:0034501)5.19964027
3DNA strand elongation involved in DNA replication (GO:0006271)4.83863645
4DNA strand elongation (GO:0022616)4.60035669
5telomere maintenance via semi-conservative replication (GO:0032201)4.52916666
6DNA replication initiation (GO:0006270)4.44786567
7negative regulation of erythrocyte differentiation (GO:0045647)4.44309818
8protein localization to chromosome, centromeric region (GO:0071459)4.37444593
9mitotic chromosome condensation (GO:0007076)4.30134076
10telomere maintenance via recombination (GO:0000722)4.26387099
11mitotic recombination (GO:0006312)4.15388571
12DNA replication-dependent nucleosome organization (GO:0034723)3.88330633
13DNA replication-dependent nucleosome assembly (GO:0006335)3.88330633
14somatic diversification of immune receptors via somatic mutation (GO:0002566)3.87308141
15somatic hypermutation of immunoglobulin genes (GO:0016446)3.87308141
16DNA replication checkpoint (GO:0000076)3.70692783
17mitotic nuclear envelope disassembly (GO:0007077)3.69749267
18mitotic sister chromatid cohesion (GO:0007064)3.68826272
19sister chromatid segregation (GO:0000819)3.67498762
20nucleotide-excision repair, DNA gap filling (GO:0006297)3.66495171
21folic acid-containing compound biosynthetic process (GO:0009396)3.64851430
22mitotic sister chromatid segregation (GO:0000070)3.64699471
23DNA geometric change (GO:0032392)3.61973753
24DNA duplex unwinding (GO:0032508)3.61006458
25positive regulation of gamma-delta T cell activation (GO:0046645)3.59268126
26kinetochore organization (GO:0051383)3.57888601
27nuclear pore complex assembly (GO:0051292)3.57827926
28telomere maintenance via telomere lengthening (GO:0010833)3.53461134
29regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.52607574
30regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.44263027
31meiotic chromosome segregation (GO:0045132)3.43336173
32nuclear pore organization (GO:0006999)3.42702645
33membrane disassembly (GO:0030397)3.42257532
34nuclear envelope disassembly (GO:0051081)3.42257532
35translesion synthesis (GO:0019985)3.41125141
36COPI coating of Golgi vesicle (GO:0048205)3.39277215
37Golgi transport vesicle coating (GO:0048200)3.39277215
38negative regulation of histone methylation (GO:0031061)3.30136990
39mitotic metaphase plate congression (GO:0007080)3.27987878
40regulation of histone H3-K9 methylation (GO:0051570)3.26623575
41heterochromatin organization (GO:0070828)3.26355552
42regulation of RNA export from nucleus (GO:0046831)3.24694609
43attachment of spindle microtubules to kinetochore (GO:0008608)3.20451063
44protein localization to chromosome (GO:0034502)3.16382040
45telomere maintenance (GO:0000723)3.15669506
46telomere organization (GO:0032200)3.11206708
47protein export from nucleus (GO:0006611)3.10035008
48metaphase plate congression (GO:0051310)3.09899460
49maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)3.07122730
50regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.06282632
51DNA replication-independent nucleosome organization (GO:0034724)3.05921543
52DNA replication-independent nucleosome assembly (GO:0006336)3.05921543
53DNA conformation change (GO:0071103)3.05805514
54ribosomal small subunit biogenesis (GO:0042274)3.04793497
55chromatin assembly or disassembly (GO:0006333)3.01788423
56establishment of chromosome localization (GO:0051303)3.00769021
57IMP biosynthetic process (GO:0006188)3.00734953
58DNA topological change (GO:0006265)3.00318736
59positive regulation of chromosome segregation (GO:0051984)3.00198512
60proline biosynthetic process (GO:0006561)2.98198968
61nucleobase-containing small molecule interconversion (GO:0015949)2.97303736
62regulation of nucleobase-containing compound transport (GO:0032239)2.95608184
63histone phosphorylation (GO:0016572)2.92602494
64regulation of spindle organization (GO:0090224)2.90113744
65regulation of sister chromatid cohesion (GO:0007063)2.89675238
66CENP-A containing nucleosome assembly (GO:0034080)2.89296105
67chromatin remodeling at centromere (GO:0031055)2.89022645
68chromosome condensation (GO:0030261)2.88802310
69regulation of gamma-delta T cell differentiation (GO:0045586)2.88223823
70kinetochore assembly (GO:0051382)2.87593470
71antigen processing and presentation of endogenous antigen (GO:0019883)2.86281282
72regulation of translational fidelity (GO:0006450)2.84292971
73negative regulation of gene silencing (GO:0060969)2.82418089
74negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.81357711
75positive regulation of DNA-dependent DNA replication (GO:2000105)2.80724999
76antigen processing and presentation of endogenous peptide antigen (GO:0002483)2.79748378
77antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)2.79748378
78positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.78476525
79pore complex assembly (GO:0046931)2.78289736
80chromatin assembly (GO:0031497)2.75319779
81spliceosomal tri-snRNP complex assembly (GO:0000244)2.74190354
82base-excision repair (GO:0006284)2.71567064
83negative regulation of RNA splicing (GO:0033119)2.71053310
84postreplication repair (GO:0006301)2.70514677
85regulation of gamma-delta T cell activation (GO:0046643)2.69519651
86positive regulation of gene expression, epigenetic (GO:0045815)2.69515565
87IMP metabolic process (GO:0046040)2.68776579
88formation of translation preinitiation complex (GO:0001731)2.67746962
89nuclear envelope organization (GO:0006998)2.67649572
90T cell apoptotic process (GO:0070231)2.66592969
91DNA synthesis involved in DNA repair (GO:0000731)2.66186157
92chromosome segregation (GO:0007059)2.65313199
93deoxyribonucleotide biosynthetic process (GO:0009263)2.64319988
94regulation of mitotic spindle organization (GO:0060236)2.63536892
95regulation of mammary gland epithelial cell proliferation (GO:0033599)2.61478938
96regulation of early endosome to late endosome transport (GO:2000641)2.60720534
97mismatch repair (GO:0006298)2.60406485
98dosage compensation (GO:0007549)2.60167530
99somatic diversification of immunoglobulins (GO:0016445)2.60124106
1003-UTR-mediated mRNA stabilization (GO:0070935)2.59572654
101ribosomal small subunit assembly (GO:0000028)2.59440485
102regulation of translational termination (GO:0006449)2.58823388
103regulation of B cell receptor signaling pathway (GO:0050855)2.58170042
104regulation of centrosome cycle (GO:0046605)2.57611992
105regulation of chromatin silencing (GO:0031935)2.57606393
106RNA stabilization (GO:0043489)2.57025561
107mRNA stabilization (GO:0048255)2.57025561
108nucleobase biosynthetic process (GO:0046112)2.56726074
109pentose-phosphate shunt (GO:0006098)2.56695983
110negative regulation of mRNA processing (GO:0050686)2.56264484
111positive regulation of B cell differentiation (GO:0045579)2.55730101
112DNA packaging (GO:0006323)2.54866800
113somatic recombination of immunoglobulin gene segments (GO:0016447)2.53616570
114positive regulation of mitotic sister chromatid separation (GO:1901970)2.52882263
115positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.52882263
116positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.52882263
117B cell receptor signaling pathway (GO:0050853)2.52244956
118isotype switching (GO:0045190)2.51937727
119regulation of exit from mitosis (GO:0007096)2.49331414
120folic acid metabolic process (GO:0046655)2.49276586
121Peyers patch development (GO:0048541)2.48928690
122mucosal-associated lymphoid tissue development (GO:0048537)2.48928690
123modulation by virus of host process (GO:0019054)2.46602609
124cellular protein complex localization (GO:0034629)2.45621541
125deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.45294826
126protoporphyrinogen IX metabolic process (GO:0046501)2.42753937
127modulation by symbiont of host cellular process (GO:0044068)2.42178973
128regulation of chromosome segregation (GO:0051983)2.41721545
129deoxyribose phosphate biosynthetic process (GO:0046385)2.40872849
1302-deoxyribonucleotide biosynthetic process (GO:0009265)2.40872849
131nucleosome disassembly (GO:0006337)2.36012868
132protein-DNA complex disassembly (GO:0032986)2.36012868
133pinocytosis (GO:0006907)2.34153241
134nuclear envelope reassembly (GO:0031468)2.33635866
135mitotic nuclear envelope reassembly (GO:0007084)2.33635866
136regulation of histone H3-K4 methylation (GO:0051569)2.31198000
137glucocorticoid receptor signaling pathway (GO:0042921)2.30988284
138negative regulation of mRNA metabolic process (GO:1903312)2.29692684
139ribonucleoprotein complex biogenesis (GO:0022613)2.28934588
140* regulation of histone H3-K27 methylation (GO:0061085)2.28519477
141positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr2.28398322
142thymic T cell selection (GO:0045061)2.28181057
143regulation of type I interferon-mediated signaling pathway (GO:0060338)2.27589273
144viral mRNA export from host cell nucleus (GO:0046784)2.27455938
145activation of Rac GTPase activity (GO:0032863)2.26701657
146establishment of mitotic spindle localization (GO:0040001)2.25337170
147spindle organization (GO:0007051)2.22822378

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1* FOXM1_23109430_ChIP-Seq_U2OS_Human5.26263589
2E2F4_17652178_ChIP-ChIP_JURKAT_Human3.70284024
3* FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.17455432
4EGR1_19374776_ChIP-ChIP_THP-1_Human3.06987175
5MYC_22102868_ChIP-Seq_BL_Human2.86782632
6EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.70703695
7MYC_18555785_ChIP-Seq_MESCs_Mouse2.68744403
8AR_21909140_ChIP-Seq_LNCAP_Human2.28066601
9E2F1_21310950_ChIP-Seq_MCF-7_Human2.23890291
10VDR_21846776_ChIP-Seq_THP-1_Human2.22261500
11NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.02439707
12MYC_19079543_ChIP-ChIP_MESCs_Mouse2.00524487
13E2F7_22180533_ChIP-Seq_HELA_Human11.0030562
14SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.85696861
15MYC_19030024_ChIP-ChIP_MESCs_Mouse1.84445510
16ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.81383651
17SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.80174059
18NELFA_20434984_ChIP-Seq_ESCs_Mouse1.74664993
19MYC_18358816_ChIP-ChIP_MESCs_Mouse1.73142845
20IRF8_22096565_ChIP-ChIP_GC-B_Human1.72386155
21MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.72055101
22XRN2_22483619_ChIP-Seq_HELA_Human1.72020540
23* NCOR1_26117541_ChIP-Seq_K562_Human1.65336719
24ZNF263_19887448_ChIP-Seq_K562_Human1.64429218
25IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.61166773
26CIITA_25753668_ChIP-Seq_RAJI_Human1.60992712
27* LXR_22292898_ChIP-Seq_THP-1_Human1.58193208
28IRF8_21731497_ChIP-ChIP_J774_Mouse1.56315575
29MYB_21317192_ChIP-Seq_ERMYB_Mouse1.56218529
30TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.56047807
31STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.55470262
32THAP11_20581084_ChIP-Seq_MESCs_Mouse1.51570061
33SCL_19346495_ChIP-Seq_HPC-7_Human1.48960587
34* KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.46552028
35MAF_26560356_Chip-Seq_TH1_Human1.43862810
36SPI1_23547873_ChIP-Seq_NB4_Human1.42794728
37UTX_26944678_Chip-Seq_JUKART_Human1.39678647
38FOXP3_21729870_ChIP-Seq_TREG_Human1.39305366
39* MYB_26560356_Chip-Seq_TH2_Human1.39195966
40VDR_23849224_ChIP-Seq_CD4+_Human1.38463246
41MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.37084000
42KDM5A_27292631_Chip-Seq_BREAST_Human1.36787276
43MYB_26560356_Chip-Seq_TH1_Human1.36139227
44FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.35602059
45SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.35552659
46VDR_24763502_ChIP-Seq_THP-1_Human1.35281665
47MYCN_18555785_ChIP-Seq_MESCs_Mouse1.34983135
48CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.34967504
49BRD4_27068464_Chip-Seq_AML-cells_Mouse1.34606295
50EST1_17652178_ChIP-ChIP_JURKAT_Human1.32428977
51ELF1_17652178_ChIP-ChIP_JURKAT_Human1.32402421
52CREB1_15753290_ChIP-ChIP_HEK293T_Human1.30381241
53RACK7_27058665_Chip-Seq_MCF-7_Human1.30290361
54KDM2B_26808549_Chip-Seq_SUP-B15_Human1.30011107
55PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.29576466
56NANOG_18555785_ChIP-Seq_MESCs_Mouse1.28442886
57TCF7_22412390_ChIP-Seq_EML_Mouse1.27611861
58MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.26628485
59SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.26120116
60TFEB_21752829_ChIP-Seq_HELA_Human1.23457795
61HOXB4_20404135_ChIP-ChIP_EML_Mouse1.22318527
62DCP1A_22483619_ChIP-Seq_HELA_Human1.22277269
63POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.20896859
64TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.20220905
65KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.20108570
66ETS1_20019798_ChIP-Seq_JURKAT_Human1.19905501
67RUNX1_22412390_ChIP-Seq_EML_Mouse1.19251057
68PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.18455820
69TTF2_22483619_ChIP-Seq_HELA_Human1.18352776
70FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.17694841
71STAT4_19710469_ChIP-ChIP_TH1__Mouse1.17393539
72NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.17107892
73HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.16831636
74NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.14722405
75ERG_20887958_ChIP-Seq_HPC-7_Mouse1.13192996
76CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.13142508
77KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.12633930
78STAT3_1855785_ChIP-Seq_MESCs_Mouse1.12244926
79GABP_19822575_ChIP-Seq_HepG2_Human1.12189218
80E2F1_18555785_ChIP-Seq_MESCs_Mouse1.12118416
81E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.11187156
82KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.11047372
83DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.10382407
84ZFX_18555785_ChIP-Seq_MESCs_Mouse1.10128843
85* MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.08342493
86RARG_19884340_ChIP-ChIP_MEFs_Mouse1.07683892
87TP63_19390658_ChIP-ChIP_HaCaT_Human1.07597002
88KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.06825873
89KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.05728416
90THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.04869605
91GABP_17652178_ChIP-ChIP_JURKAT_Human1.04510952
92GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.04111086
93CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.03499480
94KLF4_18555785_ChIP-Seq_MESCs_Mouse1.03295247
95JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.03281113
96MAF_26560356_Chip-Seq_TH2_Human1.03011647
97RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.02854556
98FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.02850346
99CTCF_27219007_Chip-Seq_ERYTHROID_Human1.02170845
100IRF8_27001747_Chip-Seq_BMDM_Mouse1.00639596
101SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.00379780
102* ATF3_27146783_Chip-Seq_COLON_Human1.00155653
103KDM2B_26808549_Chip-Seq_JURKAT_Human1.00110078
104TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse0.99774689
105* E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human0.99749503
106CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.99595898
107KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.99319585
108RUNX2_24764292_ChIP-Seq_MC3T3_Mouse0.99228549
109SRY_22984422_ChIP-ChIP_TESTIS_Rat0.99074879
110ELK1_19687146_ChIP-ChIP_HELA_Human0.98970194
111* ELK3_25401928_ChIP-Seq_HUVEC_Human0.98873072
112FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse0.98782415
113STAT3_20064451_ChIP-Seq_CD4+T_Mouse0.98597528
114* SPI1_23127762_ChIP-Seq_K562_Human0.98154277
115P300_27058665_Chip-Seq_ZR-75-30cells_Human0.97559737
116HCFC1_20581084_ChIP-Seq_MESCs_Mouse0.95992573
117YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.95471725
118GATA1_19941826_ChIP-Seq_K562_Human0.95040768
119* GATA2_22383799_ChIP-Seq_G1ME_Mouse0.93625176
120* GATA1_22383799_ChIP-Seq_G1ME_Mouse0.93124820
121STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.90876453
122KDM2B_26808549_Chip-Seq_DND41_Human0.88635779
123TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.85359242
124CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.85227170

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010094_abnormal_chromosome_stability4.01217966
2MP0003693_abnormal_embryo_hatching3.49094263
3MP0008057_abnormal_DNA_replication3.41650273
4MP0002877_abnormal_melanocyte_morpholog3.36682672
5MP0005451_abnormal_body_composition3.32992855
6MP0003111_abnormal_nucleus_morphology3.32684744
7MP0003077_abnormal_cell_cycle3.06360660
8MP0010352_gastrointestinal_tract_polyps2.83801300
9MP0002396_abnormal_hematopoietic_system2.73723956
10MP0004957_abnormal_blastocyst_morpholog2.73619412
11MP0000685_abnormal_immune_system2.37606273
12MP0010307_abnormal_tumor_latency2.33442329
13MP0001800_abnormal_humoral_immune2.21904611
14MP0001835_abnormal_antigen_presentation2.17796640
15MP0003763_abnormal_thymus_physiology2.09909503
16MP0004808_abnormal_hematopoietic_stem1.98167347
17MP0002398_abnormal_bone_marrow1.97510873
18MP0008058_abnormal_DNA_repair1.96272396
19MP0005076_abnormal_cell_differentiation1.94666532
20MP0000490_abnormal_crypts_of1.89703208
21MP0009278_abnormal_bone_marrow1.84669750
22MP0002452_abnormal_antigen_presenting1.83072239
23MP0000350_abnormal_cell_proliferation1.82670357
24MP0004185_abnormal_adipocyte_glucose1.81499135
25MP0003705_abnormal_hypodermis_morpholog1.75466550
26MP0000689_abnormal_spleen_morphology1.74420464
27MP0008007_abnormal_cellular_replicative1.74076966
28MP0003303_peritoneal_inflammation1.72306687
29MP0005058_abnormal_lysosome_morphology1.70147640
30MP0003300_gastrointestinal_ulcer1.69564762
31MP0002722_abnormal_immune_system1.67920223
32MP0009333_abnormal_splenocyte_physiolog1.66796591
33MP0001790_abnormal_immune_system1.66790592
34MP0005387_immune_system_phenotype1.66790592
35MP0000703_abnormal_thymus_morphology1.65921466
36MP0001730_embryonic_growth_arrest1.63341632
37MP0002420_abnormal_adaptive_immunity1.62786162
38MP0003436_decreased_susceptibility_to1.61674444
39MP0002019_abnormal_tumor_incidence1.61643192
40MP0004233_abnormal_muscle_weight1.59994098
41MP0001819_abnormal_immune_cell1.59980769
42MP0002723_abnormal_immune_serum1.57410039
43MP0001348_abnormal_lacrimal_gland1.54408741
44MP0000716_abnormal_immune_system1.54180742
45MP0005671_abnormal_response_to1.52450286
46MP0002166_altered_tumor_susceptibility1.52357892
47MP0001545_abnormal_hematopoietic_system1.51387344
48MP0005397_hematopoietic_system_phenotyp1.51387344
49MP0005000_abnormal_immune_tolerance1.47562837
50MP0002429_abnormal_blood_cell1.46415759
51MP0001873_stomach_inflammation1.46310180
52MP0008932_abnormal_embryonic_tissue1.45128028
53MP0002405_respiratory_system_inflammati1.44618809
54MP0000678_abnormal_parathyroid_gland1.43514318
55MP0000569_abnormal_digit_pigmentation1.40887502
56MP0008260_abnormal_autophagy1.40791706
57MP0002006_tumorigenesis1.32591805
58MP0005025_abnormal_response_to1.31594823
59MP0005464_abnormal_platelet_physiology1.30934379
60MP0010155_abnormal_intestine_physiology1.26720570
61MP0008438_abnormal_cutaneous_collagen1.25582413
62MP0003566_abnormal_cell_adhesion1.25454466
63MP0000313_abnormal_cell_death1.25389660
64MP0001697_abnormal_embryo_size1.21815139
65MP0004947_skin_inflammation1.20271686
66MP0001672_abnormal_embryogenesis/_devel1.18776498
67MP0005380_embryogenesis_phenotype1.18776498
68MP0002080_prenatal_lethality1.17108767
69MP0002419_abnormal_innate_immunity1.13460839
70MP0004197_abnormal_fetal_growth/weight/1.13085095
71MP0003448_altered_tumor_morphology1.11411151
72MP0001853_heart_inflammation1.10390381
73MP0003984_embryonic_growth_retardation1.09983712
74MP0002086_abnormal_extraembryonic_tissu1.09830327
75MP0000858_altered_metastatic_potential1.09382262
76MP0003123_paternal_imprinting1.08182852
77MP0002088_abnormal_embryonic_growth/wei1.07917053
78MP0005174_abnormal_tail_pigmentation1.03517807
79MP0002085_abnormal_embryonic_tissue1.02018632
80MP0000465_gastrointestinal_hemorrhage1.01030154
81MP0005310_abnormal_salivary_gland1.01011977
82MP0005023_abnormal_wound_healing0.99409207
83MP0003191_abnormal_cellular_cholesterol0.97464322
84MP0009785_altered_susceptibility_to0.96000559
85MP0001845_abnormal_inflammatory_respons0.95302800
86MP0001661_extended_life_span0.94400730
87MP0003866_abnormal_defecation0.93888491
88MP0005666_abnormal_adipose_tissue0.93824284
89MP0001915_intracranial_hemorrhage0.92619795
90MP0009840_abnormal_foam_cell0.91957892
91MP0003221_abnormal_cardiomyocyte_apopto0.91217891
92MP0008877_abnormal_DNA_methylation0.91189485
93MP0005621_abnormal_cell_physiology0.90612924
94MP0002084_abnormal_developmental_patter0.90519266
95MP0003950_abnormal_plasma_membrane0.86943445
96MP0000733_abnormal_muscle_development0.85329263
97MP0000477_abnormal_intestine_morphology0.84537850
98MP0000358_abnormal_cell_content/0.82875941
99MP0009931_abnormal_skin_appearance0.81320596
100MP0005501_abnormal_skin_physiology0.79045002
101MP0000371_diluted_coat_color0.78719272
102MP0002970_abnormal_white_adipose0.76599033
103MP0005623_abnormal_meninges_morphology0.75977433
104MP0003786_premature_aging0.75636359
105MP0005083_abnormal_biliary_tract0.74751272
106MP0002009_preneoplasia0.74600103
107MP0005384_cellular_phenotype0.73823075
108MP0006054_spinal_hemorrhage0.73761462
109MP0009672_abnormal_birth_weight0.73726508
110MP0001849_ear_inflammation0.72064690
111MP0002148_abnormal_hypersensitivity_rea0.71641664
112MP0002933_joint_inflammation0.70619847
113MP0000747_muscle_weakness0.69799308
114MP0000759_abnormal_skeletal_muscle0.69554086
115MP0002060_abnormal_skin_morphology0.69416376
116MP0003091_abnormal_cell_migration0.66158308
117MP0003121_genomic_imprinting0.66107674
118MP0003567_abnormal_fetal_cardiomyocyte0.65736715
119MP0006082_CNS_inflammation0.63681630
120MP0003453_abnormal_keratinocyte_physiol0.62835819
121MP0003172_abnormal_lysosome_physiology0.62228065
122MP0001119_abnormal_female_reproductive0.60775738
123MP0003656_abnormal_erythrocyte_physiolo0.60538735
124MP0000767_abnormal_smooth_muscle0.60313774
125MP0000598_abnormal_liver_morphology0.59116242
126MP0000015_abnormal_ear_pigmentation0.59035324

Predicted human phenotypes

RankGene SetZ-score
1Cholecystitis (HP:0001082)4.20912060
2Abnormal gallbladder physiology (HP:0012438)4.20912060
3Chromsome breakage (HP:0040012)3.46664815
4IgM deficiency (HP:0002850)3.38762207
5Hypertensive crisis (HP:0100735)3.21996166
6Reticulocytosis (HP:0001923)3.17733275
7Ankyloglossia (HP:0010296)3.14821247
8Abnormality of the fingertips (HP:0001211)3.14459675
9Recurrent viral infections (HP:0004429)3.13899467
10Birth length less than 3rd percentile (HP:0003561)3.13421515
11Selective tooth agenesis (HP:0001592)3.04160703
12Abnormality of chromosome stability (HP:0003220)3.03762739
13Cellulitis (HP:0100658)3.03441087
14Chromosomal breakage induced by crosslinking agents (HP:0003221)2.98919958
15Truncus arteriosus (HP:0001660)2.87098811
16Reticulocytopenia (HP:0001896)2.82466178
17Abnormality of oral frenula (HP:0000190)2.81851632
18Abnormality of reticulocytes (HP:0004312)2.81706972
19Polycythemia (HP:0001901)2.68766184
20Ependymoma (HP:0002888)2.67427948
21Insomnia (HP:0100785)2.66506682
22Fatigue (HP:0012378)2.60934784
23Disproportionate tall stature (HP:0001519)2.57458310
24Thrombocytosis (HP:0001894)2.56508813
25Agnosia (HP:0010524)2.54726596
26Recurrent fungal infections (HP:0002841)2.54704013
27Basal cell carcinoma (HP:0002671)2.54566036
28IgA deficiency (HP:0002720)2.53632591
29Recurrent abscess formation (HP:0002722)2.52871041
30Deviation of the thumb (HP:0009603)2.52227190
31Proximal placement of thumb (HP:0009623)2.51287455
32High pitched voice (HP:0001620)2.50982014
33Prominent nose (HP:0000448)2.46796524
34Medulloblastoma (HP:0002885)2.44181329
35Ectopic kidney (HP:0000086)2.43682463
36Increased connective tissue (HP:0009025)2.43428499
37Volvulus (HP:0002580)2.43308066
38Increased nuchal translucency (HP:0010880)2.39009859
39Recurrent bronchitis (HP:0002837)2.38871088
40Colon cancer (HP:0003003)2.37417894
41Agammaglobulinemia (HP:0004432)2.34803956
42Centrally nucleated skeletal muscle fibers (HP:0003687)2.34237306
43Abnormality of the tricuspid valve (HP:0001702)2.33529600
44T lymphocytopenia (HP:0005403)2.32946495
45Hyperthyroidism (HP:0000836)2.32503654
46Orthostatic hypotension (HP:0001278)2.31082879
47Lymphoma (HP:0002665)2.29797467
48Distal lower limb amyotrophy (HP:0008944)2.29012002
49Myelodysplasia (HP:0002863)2.28603628
50Bowel incontinence (HP:0002607)2.27639239
51Aplasia/Hypoplasia of the thymus (HP:0010515)2.26031991
52Abnormal large intestine physiology (HP:0012700)2.24847542
53Recurrent bacterial skin infections (HP:0005406)2.24598984
54Seborrheic dermatitis (HP:0001051)2.24305703
55Abnormality of T cell number (HP:0011839)2.23073187
56Mediastinal lymphadenopathy (HP:0100721)2.22756212
57Gastrointestinal inflammation (HP:0004386)2.22437243
58Abnormal delayed hypersensitivity skin test (HP:0002963)2.21641228
59Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.21310397
60Short 4th metacarpal (HP:0010044)2.21310397
61Progressive muscle weakness (HP:0003323)2.21189126
62Abnormality of B cell number (HP:0010975)2.20471630
63B lymphocytopenia (HP:0010976)2.20471630
64Ileus (HP:0002595)2.20421127
65Leukopenia (HP:0001882)2.20104754
66Abnormality of T cells (HP:0002843)2.17856365
67Inflammation of the large intestine (HP:0002037)2.17436649
68Abnormality of cells of the lymphoid lineage (HP:0012140)2.17240063
69Broad face (HP:0000283)2.16322646
70Overlapping toe (HP:0001845)2.16204900
71Eczematoid dermatitis (HP:0000976)2.15937695
72Meningitis (HP:0001287)2.14286616
73Colitis (HP:0002583)2.13666344
74Lymphopenia (HP:0001888)2.12301246
75Panhypogammaglobulinemia (HP:0003139)2.11967025
76Verrucae (HP:0200043)2.10852884
77Papilloma (HP:0012740)2.10852884
78Patellar dislocation (HP:0002999)2.10371675
79Cholelithiasis (HP:0001081)2.09854124
80Osteomyelitis (HP:0002754)2.08991333
81Autoimmune thrombocytopenia (HP:0001973)2.08291821
82Elevated erythrocyte sedimentation rate (HP:0003565)2.07173288
83IgG deficiency (HP:0004315)2.06964853
84Increased density of long bones (HP:0006392)2.05454650
85Achilles tendon contracture (HP:0001771)2.05167991
86Patellar aplasia (HP:0006443)2.04589341
87Obstructive lung disease (HP:0006536)2.03688388
88Chronic obstructive pulmonary disease (HP:0006510)2.03688388
89Rhabdomyosarcoma (HP:0002859)2.02159314
90Squamous cell carcinoma (HP:0002860)2.02152283
91Abnormal number of incisors (HP:0011064)1.98616310
92Meckel diverticulum (HP:0002245)1.98179941
93Breast hypoplasia (HP:0003187)1.96608841
94Deep palmar crease (HP:0006191)1.95707710
95Premature rupture of membranes (HP:0001788)1.95702806
96Abnormality of T cell physiology (HP:0011840)1.95344005
97Abnormality of the preputium (HP:0100587)1.95123131
98Cafe-au-lait spot (HP:0000957)1.94810125
99Nonimmune hydrops fetalis (HP:0001790)1.94615628
100Poikiloderma (HP:0001029)1.94610321
101Flat cornea (HP:0007720)1.94469393
102Aplasia/Hypoplasia of the uvula (HP:0010293)1.93971488
103Long palpebral fissure (HP:0000637)1.93865682
104Abnormality of DNA repair (HP:0003254)1.93378617
105Microvesicular hepatic steatosis (HP:0001414)1.92633110
106Abnormality of the calcaneus (HP:0008364)1.92252795
107Pustule (HP:0200039)1.92055518
108Entropion (HP:0000621)1.90379222
109Abnormality of the astrocytes (HP:0100707)1.90225720
110Astrocytoma (HP:0009592)1.90225720
111Gastrointestinal stroma tumor (HP:0100723)1.89754538
112Long eyelashes (HP:0000527)1.88682295
113Abnormality of the ileum (HP:0001549)1.88662298
114Ulnar bowing (HP:0003031)1.88452012
115Absent thumb (HP:0009777)1.87763254
116Duplicated collecting system (HP:0000081)1.87339016
117Bone marrow hypocellularity (HP:0005528)1.87253131
118Recurrent cutaneous fungal infections (HP:0011370)1.86999420
119Chronic mucocutaneous candidiasis (HP:0002728)1.86999420
120Ragged-red muscle fibers (HP:0003200)1.86311394
121Amaurosis fugax (HP:0100576)1.86179304
122Combined immunodeficiency (HP:0005387)1.86012514
12311 pairs of ribs (HP:0000878)1.85870282
124Pointed chin (HP:0000307)1.85716911
125Abnormality of cells of the erythroid lineage (HP:0012130)1.85662018
126Gastrointestinal dysmotility (HP:0002579)1.85211291
127Blepharitis (HP:0000498)1.84831889
128Myositis (HP:0100614)1.84786010
129Vertebral compression fractures (HP:0002953)1.84610966
130Progressive external ophthalmoplegia (HP:0000590)1.83768789
131Periodontitis (HP:0000704)1.83135805
132Trismus (HP:0000211)1.82790083
133Abnormality of glycolysis (HP:0004366)1.80973021
134Aplasia/Hypoplasia of the patella (HP:0006498)1.80527458
135Cutis marmorata (HP:0000965)1.79043055
136Abnormal number of erythroid precursors (HP:0012131)1.78683023
137Distal upper limb amyotrophy (HP:0007149)1.78632743
138Upper limb amyotrophy (HP:0009129)1.78632743
139Recurrent lower respiratory tract infections (HP:0002783)1.78448307
140Hematochezia (HP:0002573)1.77171708
141Abnormality of the renal collecting system (HP:0004742)1.77039402
142Vasculitis (HP:0002633)1.76565799
143Impulsivity (HP:0100710)1.76236760
144Pallor (HP:0000980)1.75933360
145Chronic otitis media (HP:0000389)1.75728126
146Acute myeloid leukemia (HP:0004808)1.75068093
147Hyperacusis (HP:0010780)1.74072996
148Deep philtrum (HP:0002002)1.73840488
149Hypoparathyroidism (HP:0000829)1.73669125
150Flared metaphyses (HP:0003015)1.73310584
151Dilatation of the ascending aorta (HP:0005111)1.72874956
152Upper limb muscle weakness (HP:0003484)1.69471087
153Abnormality of the Achilles tendon (HP:0005109)1.67474680
154Protrusio acetabuli (HP:0003179)1.67213929
155Abnormality of the gallbladder (HP:0005264)1.66731036
156Viral hepatitis (HP:0006562)1.65258351
157Parkinsonism with favorable response to dopaminergic medication (HP:0002548)1.64189807
158Myopathic facies (HP:0002058)1.62957582
159Abnormal gallbladder morphology (HP:0012437)1.62906275
160Osteolytic defects of the phalanges of the hand (HP:0009771)1.62759543
161Osteolytic defects of the hand bones (HP:0009699)1.62759543
162Granulocytopenia (HP:0001913)1.62744235
163Biconcave vertebral bodies (HP:0004586)1.62474272
164Increased IgE level (HP:0003212)1.62331390
165Renal duplication (HP:0000075)1.61699792
166Dislocated radial head (HP:0003083)1.61697190
167Abnormality of the thymus (HP:0000777)1.61565423
168Rough bone trabeculation (HP:0100670)1.61211692
169Broad distal phalanx of finger (HP:0009836)1.59192562
170Metaphyseal cupping (HP:0003021)1.58180822
171Atelectasis (HP:0100750)1.57917275
172Relative macrocephaly (HP:0004482)1.55475373
173Premature skin wrinkling (HP:0100678)1.55398678
174Elbow flexion contracture (HP:0002987)1.55391640
175Sandal gap (HP:0001852)1.55186447

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDC74.55383409
2PRPF4B3.35437910
3MAP4K13.28620353
4EEF2K3.19085117
5CDK123.12377933
6SMG12.92180472
7IRAK32.88681217
8NEK22.81020886
9ICK2.69467732
10PKN22.61015439
11STK102.60087571
12MAP3K102.39839132
13WEE12.25774575
14RIPK42.13258818
15BUB12.07306328
16TRIB32.03152505
17TTK1.87010005
18KSR21.84157115
19BLK1.73527422
20EIF2AK11.71991725
21ATR1.62476160
22JAK31.61728406
23CDK41.59953621
24RPS6KA41.59634832
25LRRK21.58526214
26SIK11.50042527
27MAP3K81.45661404
28ERN11.41928645
29TYK21.40517288
30MAP3K131.39466585
31TAOK21.36953209
32CSF1R1.35864008
33BRD41.35719979
34TAOK31.35213024
35TESK21.32972803
36RPS6KB21.27478878
37BTK1.26338913
38CDK71.26193976
39PIM11.24842603
40AURKB1.22316565
41FGFR41.21454006
42CLK11.20925475
43ACVR1B1.19671227
44PLK11.18412410
45GRK61.15125635
46ZAP701.14266166
47PLK41.13431482
48PASK1.13129767
49RAF11.12446159
50EIF2AK31.07085783
51STK41.05742996
52TBK11.03192322
53SYK1.01241664
54TTN0.99516465
55CDK60.99311265
56CCNB10.99021220
57MELK0.98561005
58CHEK10.98151589
59NME20.97987407
60MST1R0.97445288
61BRAF0.96382244
62MAP2K30.94006289
63CHEK20.93811459
64STK30.91509676
65FLT30.91352177
66SCYL20.91165018
67ALK0.88578193
68MKNK10.84607560
69PTK60.83981970
70PAK40.83058493
71DYRK30.82383785
72SIK30.81339992
73KIT0.78592936
74TGFBR10.77970461
75BRSK20.77321060
76NEK10.76303210
77ATM0.75795603
78PDGFRA0.75008539
79PBK0.74114706
80BMPR20.73839332
81MAP3K10.72673205
82ARAF0.70403893
83CDK80.69933322
84MOS0.68731499
85BMX0.68106284
86LCK0.67680791
87MAPKAPK30.67253111
88MTOR0.67184859
89CDK20.66928932
90MAP3K140.66554549
91SRPK10.66551054
92CDK90.64715923
93PAK10.64661264
94HCK0.63635490
95TSSK60.63103842
96TXK0.62902973
97IRAK20.61623096
98EPHB10.61136549
99IKBKB0.59720388
100ITK0.58010834
101BRSK10.57605815
102TNK20.56947088
103ILK0.56189737
104LYN0.55517374
105AURKA0.55375852
106CHUK0.55116653
107VRK20.53826058
108KSR10.51629256
109IRAK40.51416197
110TEC0.47927727
111IKBKE0.47544357
112CAMK1D0.47502096
113HIPK20.46773622
114MAP3K20.46162004
115CSK0.46039989
116MARK30.45819131
117TRPM70.45344540
118CDK10.44345209
119MAPK110.44236817
120NEK90.42657914
121SIK20.42535983
122RPS6KA60.41967456
123TESK10.41714808
124RET0.41343939
125MKNK20.41173178
126TLK10.39828319
127CDC42BPA0.39287865
128PAK20.38606953
129MST40.37681250
130LATS10.37522550
131KDR0.37085976
132PDPK10.36973163
133TAOK10.35812168
134JAK20.35518530
135MAPKAPK20.35420652
136NME10.33836962

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030305.08436619
2Mismatch repair_Homo sapiens_hsa034304.07104515
3Base excision repair_Homo sapiens_hsa034103.00072277
4Homologous recombination_Homo sapiens_hsa034402.85750512
5Cell cycle_Homo sapiens_hsa041102.73843606
6Non-homologous end-joining_Homo sapiens_hsa034502.58321564
7One carbon pool by folate_Homo sapiens_hsa006702.48826870
8Nucleotide excision repair_Homo sapiens_hsa034202.24957611
9Primary immunodeficiency_Homo sapiens_hsa053402.20624119
10Butirosin and neomycin biosynthesis_Homo sapiens_hsa005242.13918800
11Spliceosome_Homo sapiens_hsa030402.13727434
12RNA transport_Homo sapiens_hsa030132.04478989
13Fanconi anemia pathway_Homo sapiens_hsa034601.90515123
14Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.80069442
15Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.79882262
16B cell receptor signaling pathway_Homo sapiens_hsa046621.76647491
17Antigen processing and presentation_Homo sapiens_hsa046121.67719428
18p53 signaling pathway_Homo sapiens_hsa041151.52568824
19NF-kappa B signaling pathway_Homo sapiens_hsa040641.51196106
20Ribosome_Homo sapiens_hsa030101.50138185
21Other glycan degradation_Homo sapiens_hsa005111.43678217
22Central carbon metabolism in cancer_Homo sapiens_hsa052301.43167669
23RNA degradation_Homo sapiens_hsa030181.40499123
24Pyrimidine metabolism_Homo sapiens_hsa002401.38167916
25Herpes simplex infection_Homo sapiens_hsa051681.38080850
26Measles_Homo sapiens_hsa051621.30530616
27Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.30215000
28Intestinal immune network for IgA production_Homo sapiens_hsa046721.29903007
29Chronic myeloid leukemia_Homo sapiens_hsa052201.29901609
30Viral carcinogenesis_Homo sapiens_hsa052031.25305331
31HTLV-I infection_Homo sapiens_hsa051661.22820075
32Renal cell carcinoma_Homo sapiens_hsa052111.22161036
33mRNA surveillance pathway_Homo sapiens_hsa030151.21873233
34Small cell lung cancer_Homo sapiens_hsa052221.21675330
35Leishmaniasis_Homo sapiens_hsa051401.17583578
36MicroRNAs in cancer_Homo sapiens_hsa052061.13510044
37Apoptosis_Homo sapiens_hsa042101.12717170
38Glioma_Homo sapiens_hsa052141.10090798
39Epstein-Barr virus infection_Homo sapiens_hsa051691.09832786
40Hepatitis B_Homo sapiens_hsa051611.08927033
41Pancreatic cancer_Homo sapiens_hsa052121.07385016
42Fructose and mannose metabolism_Homo sapiens_hsa000511.06349281
43Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.05843786
44Osteoclast differentiation_Homo sapiens_hsa043801.01888183
45Transcriptional misregulation in cancer_Homo sapiens_hsa052020.98856595
46Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.97747053
47Shigellosis_Homo sapiens_hsa051310.96502265
48Non-small cell lung cancer_Homo sapiens_hsa052230.94066786
49Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.92141335
50Prion diseases_Homo sapiens_hsa050200.91702181
51RNA polymerase_Homo sapiens_hsa030200.90940748
52ErbB signaling pathway_Homo sapiens_hsa040120.90862193
53Carbon metabolism_Homo sapiens_hsa012000.89926685
54Acute myeloid leukemia_Homo sapiens_hsa052210.89852878
55T cell receptor signaling pathway_Homo sapiens_hsa046600.89363554
56Legionellosis_Homo sapiens_hsa051340.87607292
57Lysine degradation_Homo sapiens_hsa003100.86691670
58Influenza A_Homo sapiens_hsa051640.85325971
59Selenocompound metabolism_Homo sapiens_hsa004500.84826953
60Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.84440016
61NOD-like receptor signaling pathway_Homo sapiens_hsa046210.84402675
62Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.84312751
63Viral myocarditis_Homo sapiens_hsa054160.83304952
64Colorectal cancer_Homo sapiens_hsa052100.82357744
65Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.82125838
66Hematopoietic cell lineage_Homo sapiens_hsa046400.79981940
67Leukocyte transendothelial migration_Homo sapiens_hsa046700.78648547
68Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.77950131
69Prolactin signaling pathway_Homo sapiens_hsa049170.75158814
70Toxoplasmosis_Homo sapiens_hsa051450.74036837
71Systemic lupus erythematosus_Homo sapiens_hsa053220.73721698
72Thyroid hormone signaling pathway_Homo sapiens_hsa049190.68885991
73Jak-STAT signaling pathway_Homo sapiens_hsa046300.67755228
74Galactose metabolism_Homo sapiens_hsa000520.66214296
75Basal transcription factors_Homo sapiens_hsa030220.66180349
76Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.65071451
77Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.64265600
78Toll-like receptor signaling pathway_Homo sapiens_hsa046200.64239200
79RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.64205126
80Insulin signaling pathway_Homo sapiens_hsa049100.64165556
81Prostate cancer_Homo sapiens_hsa052150.62665367
82N-Glycan biosynthesis_Homo sapiens_hsa005100.62108713
83Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.59743839
84Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.58686813
85Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.55526637
86AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.53949398
87Sulfur relay system_Homo sapiens_hsa041220.53737303
88TNF signaling pathway_Homo sapiens_hsa046680.52844169
89Tuberculosis_Homo sapiens_hsa051520.52092938
90Neurotrophin signaling pathway_Homo sapiens_hsa047220.50677694
912-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.50674671
92Salmonella infection_Homo sapiens_hsa051320.50212122
93Bladder cancer_Homo sapiens_hsa052190.50203652
94Focal adhesion_Homo sapiens_hsa045100.49946909
95Thyroid cancer_Homo sapiens_hsa052160.49618433
96Graft-versus-host disease_Homo sapiens_hsa053320.49533290
97Oocyte meiosis_Homo sapiens_hsa041140.49339855
98Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.48551082
99Hepatitis C_Homo sapiens_hsa051600.48517518
100Notch signaling pathway_Homo sapiens_hsa043300.47589314
101Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.47423101
102Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.44435396
103mTOR signaling pathway_Homo sapiens_hsa041500.44378700
104Platelet activation_Homo sapiens_hsa046110.44034164
105Alcoholism_Homo sapiens_hsa050340.43619775
106Proteoglycans in cancer_Homo sapiens_hsa052050.43614653
107Sphingolipid signaling pathway_Homo sapiens_hsa040710.42650620
108Inositol phosphate metabolism_Homo sapiens_hsa005620.42198476
109Biosynthesis of amino acids_Homo sapiens_hsa012300.42164989
110HIF-1 signaling pathway_Homo sapiens_hsa040660.40931031
111Asthma_Homo sapiens_hsa053100.40368458
112VEGF signaling pathway_Homo sapiens_hsa043700.40317191
113Pentose phosphate pathway_Homo sapiens_hsa000300.39742514
114Allograft rejection_Homo sapiens_hsa053300.39702444
115Endometrial cancer_Homo sapiens_hsa052130.39070508
116Proteasome_Homo sapiens_hsa030500.38852582
117Pertussis_Homo sapiens_hsa051330.37182678
118Purine metabolism_Homo sapiens_hsa002300.36868642
119Drug metabolism - other enzymes_Homo sapiens_hsa009830.36749691
120Pathways in cancer_Homo sapiens_hsa052000.34994724
121Malaria_Homo sapiens_hsa051440.34836252
122Chemokine signaling pathway_Homo sapiens_hsa040620.34730466
123Cysteine and methionine metabolism_Homo sapiens_hsa002700.34449536
124FoxO signaling pathway_Homo sapiens_hsa040680.34115147

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