PHF20L1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G6.05026844
2positive regulation of gamma-delta T cell activation (GO:0046645)5.33815381
3negative regulation of cell killing (GO:0031342)4.76973963
4negative regulation of leukocyte mediated cytotoxicity (GO:0001911)4.76973963
5monoubiquitinated protein deubiquitination (GO:0035520)4.63715017
6neural tube formation (GO:0001841)4.24455031
7negative T cell selection (GO:0043383)4.04945697
8negative thymic T cell selection (GO:0045060)3.89978440
9neutrophil mediated immunity (GO:0002446)3.86363182
10detection of molecule of bacterial origin (GO:0032490)3.86121081
11antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.85275100
12antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.85275100
13definitive hemopoiesis (GO:0060216)3.83662832
14histone H3-K4 trimethylation (GO:0080182)3.81865845
15regulation of gamma-delta T cell activation (GO:0046643)3.77596470
16interkinetic nuclear migration (GO:0022027)3.76001175
17retrograde transport, vesicle recycling within Golgi (GO:0000301)3.70482954
18regulation of gamma-delta T cell differentiation (GO:0045586)3.69919174
19positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)3.68892061
20cellular response to ethanol (GO:0071361)3.66121882
21positive T cell selection (GO:0043368)3.65982357
22negative regulation of neurotransmitter secretion (GO:0046929)3.63791288
23protein targeting to Golgi (GO:0000042)3.58738806
24positive thymic T cell selection (GO:0045059)3.56910874
25establishment of protein localization to Golgi (GO:0072600)3.51031238
26microglial cell activation (GO:0001774)3.50554611
27dosage compensation (GO:0007549)3.49089274
28positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.48828498
29myeloid leukocyte mediated immunity (GO:0002444)3.48744976
30regulation of B cell receptor signaling pathway (GO:0050855)3.38381455
31negative regulation of neurotransmitter transport (GO:0051589)3.36254297
32cellular extravasation (GO:0045123)3.35137335
33antigen processing and presentation of endogenous antigen (GO:0019883)3.34791014
34positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)3.34021278
35nerve growth factor signaling pathway (GO:0038180)3.32235039
36macrophage activation (GO:0042116)3.30195981
37leukocyte aggregation (GO:0070486)3.29442300
38T cell selection (GO:0045058)3.28810983
39peptidyl-lysine trimethylation (GO:0018023)3.28554175
40cytoplasmic mRNA processing body assembly (GO:0033962)3.23032407
41regulation of pigment cell differentiation (GO:0050932)3.20081945
42thymic T cell selection (GO:0045061)3.14632183
43regulation of interleukin-12 biosynthetic process (GO:0045075)3.12679935
44response to interleukin-15 (GO:0070672)3.10329905
45interferon-gamma production (GO:0032609)3.07679928
46histone mRNA catabolic process (GO:0071044)2.99328406
47regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.95609777
48hepatocyte apoptotic process (GO:0097284)2.92774117
49lymph vessel development (GO:0001945)2.91729231
50histone H3-K36 demethylation (GO:0070544)2.89799437
51protein K48-linked deubiquitination (GO:0071108)2.86337622
52macrophage activation involved in immune response (GO:0002281)2.85774965
53positive regulation of developmental pigmentation (GO:0048087)2.84921686
54activated T cell proliferation (GO:0050798)2.83996171
55cerebellar Purkinje cell differentiation (GO:0021702)2.82624371
56positive regulation of mast cell activation (GO:0033005)2.81788772
57negative regulation of T cell mediated immunity (GO:0002710)2.81714928
58natural killer cell activation involved in immune response (GO:0002323)2.79164787
59cellular response to interleukin-15 (GO:0071350)2.79049842
60regulation of isotype switching to IgG isotypes (GO:0048302)2.79036928
61protein K63-linked deubiquitination (GO:0070536)2.78733525
62megakaryocyte development (GO:0035855)2.73950759
63negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)2.71731822
64negative regulation of T-helper cell differentiation (GO:0045623)2.71731822
65positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.68895237
66regulation of necroptotic process (GO:0060544)2.66970714
67regulation of regulatory T cell differentiation (GO:0045589)2.66881674
68detection of bacterium (GO:0016045)2.66643424
69regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition 2.65696195
70nucleus localization (GO:0051647)2.65061525
71protein K11-linked deubiquitination (GO:0035871)2.63107515
72CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294)2.61989399
73T-helper cell differentiation (GO:0042093)2.61989399
74regulation of nitric-oxide synthase biosynthetic process (GO:0051769)2.61566363
75regulation of B cell differentiation (GO:0045577)2.59977566
76positive regulation of granulocyte differentiation (GO:0030854)2.59801449
77embryonic process involved in female pregnancy (GO:0060136)2.59477432
78centriole replication (GO:0007099)2.55391719
79T cell costimulation (GO:0031295)2.55211061
80ER overload response (GO:0006983)2.54995203
81cellular response to zinc ion (GO:0071294)2.54705713
82regulation of establishment of cell polarity (GO:2000114)2.54457226
83embryonic hemopoiesis (GO:0035162)2.54387939
84negative regulation of adaptive immune response based on somatic recombination of immune receptors b2.54218596
85regulation of antigen receptor-mediated signaling pathway (GO:0050854)2.52057971
86lymphocyte costimulation (GO:0031294)2.51421890
87regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.51130512
88Golgi to endosome transport (GO:0006895)2.50735706
89CD4-positive, alpha-beta T cell differentiation (GO:0043367)2.50393900
90T cell receptor signaling pathway (GO:0050852)2.50280291
91detection of other organism (GO:0098543)2.50105028
92T cell homeostasis (GO:0043029)2.49925499
93protein localization to Golgi apparatus (GO:0034067)2.49789760
94negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)2.49386269
95alpha-beta T cell differentiation (GO:0046632)2.47511543
96negative regulation of NF-kappaB import into nucleus (GO:0042347)2.46793127
97B cell receptor signaling pathway (GO:0050853)2.44787640
98positive regulation of histone deacetylation (GO:0031065)2.44041716
99T cell migration (GO:0072678)2.44004900
100negative regulation of interleukin-17 production (GO:0032700)2.42669224
101positive regulation of mast cell degranulation (GO:0043306)2.42173798
102positive regulation of mast cell activation involved in immune response (GO:0033008)2.42173798
103signal peptide processing (GO:0006465)2.40341027
104interleukin-6-mediated signaling pathway (GO:0070102)2.39607283
105antigen receptor-mediated signaling pathway (GO:0050851)2.38714750
106negative regulation of bone resorption (GO:0045779)2.38697858
107positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr2.37628804
108T cell differentiation (GO:0030217)2.36610632
109positive regulation of interleukin-2 production (GO:0032743)2.34329578
110detection of external biotic stimulus (GO:0098581)2.33628000
111negative regulation of bone remodeling (GO:0046851)2.33497513
112modulation by organism of defense response of other organism involved in symbiotic interaction (GO:02.32823384
113positive regulation by organism of defense response of other organism involved in symbiotic interact2.32823384
114modulation by symbiont of host immune response (GO:0052553)2.32823384
115positive regulation by symbiont of host defense response (GO:0052509)2.32823384
116modulation by symbiont of host defense response (GO:0052031)2.32823384
117modulation by organism of immune response of other organism involved in symbiotic interaction (GO:002.32823384
118central nervous system neuron axonogenesis (GO:0021955)2.32816925
119positive regulation of phosphoprotein phosphatase activity (GO:0032516)2.32660687
120regulation of alpha-beta T cell proliferation (GO:0046640)2.32565274
121alpha-beta T cell activation (GO:0046631)2.32071234
122early endosome to late endosome transport (GO:0045022)2.31912645
123neutrophil activation (GO:0042119)2.30660489
124negative regulation of osteoblast proliferation (GO:0033689)2.30579754
125peptidyl-lysine methylation (GO:0018022)2.30569367
126lymphocyte homeostasis (GO:0002260)2.30553259
127regulation of T cell tolerance induction (GO:0002664)2.30181315
128heterotypic cell-cell adhesion (GO:0034113)2.29811311
129centrosome localization (GO:0051642)2.29544906
130germ cell migration (GO:0008354)2.29474676
131snRNA transcription (GO:0009301)2.29232874
132venous blood vessel morphogenesis (GO:0048845)2.29149703
133positive regulation of natural killer cell differentiation (GO:0032825)2.29062944
134microtubule anchoring (GO:0034453)2.28891682
135antigen processing and presentation via MHC class Ib (GO:0002475)2.28818445
136neutrophil activation involved in immune response (GO:0002283)2.28161792
137cellular response to epinephrine stimulus (GO:0071872)2.27962042
138negative regulation of adaptive immune response (GO:0002820)2.27954625
139B cell homeostasis (GO:0001782)2.27880105
140positive regulation of B cell differentiation (GO:0045579)2.27710785
141regulation of T cell receptor signaling pathway (GO:0050856)2.27444164
142histone H3-K9 modification (GO:0061647)2.27298897
143protein ubiquitination involved in ubiquitin-dependent protein catabolic process (GO:0042787)2.27138730
144response to epinephrine (GO:0071871)2.26706118
145alpha-beta T cell differentiation involved in immune response (GO:0002293)2.25398608
146alpha-beta T cell activation involved in immune response (GO:0002287)2.25398608
147T cell differentiation involved in immune response (GO:0002292)2.25398608
148positive regulation of alpha-beta T cell proliferation (GO:0046641)2.25392467
149monocyte differentiation (GO:0030224)2.24402899
150mast cell activation (GO:0045576)2.23790335
151natural killer cell differentiation (GO:0001779)2.23630730
152histone H3-K9 methylation (GO:0051567)2.23043355
153intra-Golgi vesicle-mediated transport (GO:0006891)2.21929574
154response to host immune response (GO:0052572)2.21726748
155response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.21726748
156phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)2.21249921
157central nervous system projection neuron axonogenesis (GO:0021952)2.20745167
158regulation of respiratory system process (GO:0044065)2.20336072
159negative regulation of B cell proliferation (GO:0030889)2.20317669
160nuclear pore complex assembly (GO:0051292)2.20069380
161regulation of sarcomere organization (GO:0060297)2.19893037
162JAK-STAT cascade (GO:0007259)2.19594925
163response to type I interferon (GO:0034340)2.19072072
164regulation of DNA endoreduplication (GO:0032875)2.19052052

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXP3_17237761_ChIP-ChIP_TREG_Mouse5.39712848
2STAT6_20620947_ChIP-Seq_CD4_POS_T_Human4.30663229
3IRF8_22096565_ChIP-ChIP_GC-B_Human2.84312258
4RUNX_20019798_ChIP-Seq_JUKART_Human2.83055657
5STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.65803932
6SMAD_19615063_ChIP-ChIP_OVARY_Human2.62146133
7CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.43925941
8SCL_19346495_ChIP-Seq_HPC-7_Human2.41260289
9TAF15_26573619_Chip-Seq_HEK293_Human2.29817275
10VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human2.22017399
11FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.20968008
12IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.16032426
13FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse2.15131955
14MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.14902916
15IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.98725726
16* SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.91183651
17POU3F2_20337985_ChIP-ChIP_501MEL_Human1.89715417
18ER_23166858_ChIP-Seq_MCF-7_Human1.79823978
19IGF1R_20145208_ChIP-Seq_DFB_Human1.78749509
20RBPJ_22232070_ChIP-Seq_NCS_Mouse1.74508156
21ZNF217_24962896_ChIP-Seq_MCF-7_Human1.69905317
22AR_21572438_ChIP-Seq_LNCaP_Human1.65146583
23IRF8_27001747_Chip-Seq_BMDM_Mouse1.64159211
24RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.61687595
25NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.61488742
26TP53_16413492_ChIP-PET_HCT116_Human1.61127363
27NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.59206976
28* GBX2_23144817_ChIP-Seq_PC3_Human1.59082230
29GATA2_21666600_ChIP-Seq_HMVEC_Human1.58202714
30MYB_26560356_Chip-Seq_TH2_Human1.57459142
31SUZ12_27294783_Chip-Seq_NPCs_Mouse1.53013601
32PIAS1_25552417_ChIP-Seq_VCAP_Human1.48406044
33BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.46914602
34GATA1_22025678_ChIP-Seq_K562_Human1.45792642
35SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.43518647
36CDX2_19796622_ChIP-Seq_MESCs_Mouse1.43290149
37Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.42990000
38CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.42970073
39MYB_21317192_ChIP-Seq_ERMYB_Mouse1.39890760
40CBP_20019798_ChIP-Seq_JUKART_Human1.37351109
41IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.37351109
42NFE2_27457419_Chip-Seq_LIVER_Mouse1.36979414
43UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.36730616
44CTBP2_25329375_ChIP-Seq_LNCAP_Human1.36545777
45RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.35900220
46PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.35867003
47MYB_26560356_Chip-Seq_TH1_Human1.35613818
48TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.35346488
49FLI1_27457419_Chip-Seq_LIVER_Mouse1.34514854
50VDR_24787735_ChIP-Seq_THP-1_Human1.33730604
51SPI1_23127762_ChIP-Seq_K562_Human1.31851155
52STAT4_19710469_ChIP-ChIP_TH1__Mouse1.31235997
53GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.30122022
54ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.27366142
55ZNF274_21170338_ChIP-Seq_K562_Hela1.27338810
56HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.27220892
57GATA3_27048872_Chip-Seq_THYMUS_Human1.25303064
58FLI1_21867929_ChIP-Seq_TH2_Mouse1.24515562
59TOP2B_26459242_ChIP-Seq_MCF-7_Human1.24331353
60PRDM14_20953172_ChIP-Seq_ESCs_Human1.24297320
61OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.24245033
62P300_19829295_ChIP-Seq_ESCs_Human1.23968841
63ESR1_20079471_ChIP-ChIP_T-47D_Human1.22126856
64VDR_22108803_ChIP-Seq_LS180_Human1.22057632
65WT1_19549856_ChIP-ChIP_CCG9911_Human1.21144893
66CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.21095948
67EGR1_19374776_ChIP-ChIP_THP-1_Human1.20362850
68AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.20238074
69SMAD4_21799915_ChIP-Seq_A2780_Human1.19571681
70TP53_18474530_ChIP-ChIP_U2OS_Human1.19383056
71TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.18703178
72GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.18413766
73STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.17875537
74* STAT3_23295773_ChIP-Seq_U87_Human1.16927076
75OCT4_21477851_ChIP-Seq_ESCs_Mouse1.16741927
76NANOG_18555785_Chip-Seq_ESCs_Mouse1.16714624
77* ARNT_22903824_ChIP-Seq_MCF-7_Human1.16576500
78BP1_19119308_ChIP-ChIP_Hs578T_Human1.16313262
79PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.15344709
80CTBP1_25329375_ChIP-Seq_LNCAP_Human1.14844271
81* ZFP57_27257070_Chip-Seq_ESCs_Mouse1.14403037
82CRX_20693478_ChIP-Seq_RETINA_Mouse1.12657581
83RXR_22108803_ChIP-Seq_LS180_Human1.10885363
84SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.10872892
85P53_22387025_ChIP-Seq_ESCs_Mouse1.08120218
86AHR_22903824_ChIP-Seq_MCF-7_Human1.07557090
87VDR_24763502_ChIP-Seq_THP-1_Human1.06839740
88PCGF2_27294783_Chip-Seq_ESCs_Mouse1.06547992
89EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.06265864
90CJUN_26792858_Chip-Seq_BT549_Human1.05422024
91E2F1_18555785_Chip-Seq_ESCs_Mouse1.05111379
92BRD4_25478319_ChIP-Seq_HGPS_Human1.04346496
93SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse1.04141024
94P300_18555785_Chip-Seq_ESCs_Mouse1.03443940
95FOXM1_26456572_ChIP-Seq_MCF-7_Human1.02999360
96EP300_21415370_ChIP-Seq_HL-1_Mouse1.02849719
97TCF4_18268006_ChIP-ChIP_LS174T_Human1.02417984
98TP63_23658742_ChIP-Seq_EP156T_Human1.01839287
99TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.01732971
100EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.01554954
101MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.00884523
102OCT4_18555785_Chip-Seq_ESCs_Mouse1.00383073
103POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.00322611
104TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.00322611
105EZH2_22144423_ChIP-Seq_EOC_Human1.00186208
106BCAT_22108803_ChIP-Seq_LS180_Human1.00002807
107TCF4_23295773_ChIP-Seq_U87_Human0.99500468
108IRF8_21731497_ChIP-ChIP_J774_Mouse0.98685581
109FUS_26573619_Chip-Seq_HEK293_Human0.98675415
110EWS_26573619_Chip-Seq_HEK293_Human0.98508563
111PCGF2_27294783_Chip-Seq_NPCs_Mouse0.98349773
112TCF7_22412390_ChIP-Seq_EML_Mouse0.98300231
113PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse0.96370242
114PU_27001747_Chip-Seq_BMDM_Mouse0.96167635
115MAF_26560356_Chip-Seq_TH1_Human0.96054091
116EZH2_27294783_Chip-Seq_NPCs_Mouse0.95949193
117DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.95356898
118SALL1_21062744_ChIP-ChIP_HESCs_Human0.95177520
119* TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.93909633
120CTNNB1_20460455_ChIP-Seq_HCT116_Human0.92833229
121SUZ12_18555785_Chip-Seq_ESCs_Mouse0.92660726
122CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.92587254
123SMAD3_21741376_ChIP-Seq_EPCs_Human0.92303525
124NRF2_20460467_ChIP-Seq_MEFs_Mouse0.92174874
125NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.92174874
126SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.91378271
127NR3C1_21868756_ChIP-Seq_MCF10A_Human0.90678879
128AR_25329375_ChIP-Seq_VCAP_Human0.89760829
129SOX2_21211035_ChIP-Seq_LN229_Gbm0.89759682
130GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.89164329
131RUNX1_22412390_ChIP-Seq_EML_Mouse0.88576222
132CMYC_18555785_Chip-Seq_ESCs_Mouse0.88419469
133RUNX2_22187159_ChIP-Seq_PCA_Human0.88170023

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008057_abnormal_DNA_replication4.27207374
2MP0000569_abnormal_digit_pigmentation3.42032389
3MP0002166_altered_tumor_susceptibility3.31847839
4MP0003300_gastrointestinal_ulcer3.03220289
5MP0002009_preneoplasia3.02217349
6MP0003828_pulmonary_edema3.01054631
7MP0005671_abnormal_response_to2.89645351
8MP0003763_abnormal_thymus_physiology2.83069061
9MP0001835_abnormal_antigen_presentation2.65681462
10MP0000427_abnormal_hair_cycle2.64952641
11MP0001879_abnormal_lymphatic_vessel2.43495934
12MP0002877_abnormal_melanocyte_morpholog2.33609662
13MP0002006_tumorigenesis2.26997566
14MP0003303_peritoneal_inflammation2.22399110
15MP0001790_abnormal_immune_system2.22228696
16MP0005387_immune_system_phenotype2.22228696
17MP0004130_abnormal_muscle_cell2.10336316
18MP0004883_abnormal_blood_vessel2.06511358
19MP0009278_abnormal_bone_marrow2.05209010
20MP0002396_abnormal_hematopoietic_system2.01124231
21MP0010386_abnormal_urinary_bladder2.00749071
22MP0000685_abnormal_immune_system1.91122161
23MP0005423_abnormal_somatic_nervous1.89434502
24MP0005171_absent_coat_pigmentation1.88707439
25MP0001800_abnormal_humoral_immune1.88682339
26MP0002420_abnormal_adaptive_immunity1.86882443
27MP0004808_abnormal_hematopoietic_stem1.86290339
28MP0005409_darkened_coat_color1.86101924
29MP0003787_abnormal_imprinting1.85646238
30MP0005000_abnormal_immune_tolerance1.84974360
31MP0000015_abnormal_ear_pigmentation1.83208869
32MP0001819_abnormal_immune_cell1.81979802
33MP0004510_myositis1.77764168
34MP0002452_abnormal_antigen_presenting1.76913828
35MP0008877_abnormal_DNA_methylation1.75920164
36MP0003656_abnormal_erythrocyte_physiolo1.75741811
37MP0009780_abnormal_chondrocyte_physiolo1.73943313
38MP0002723_abnormal_immune_serum1.70575725
39MP0002419_abnormal_innate_immunity1.70428863
40MP0003183_abnormal_peptide_metabolism1.67714511
41MP0002398_abnormal_bone_marrow1.66210336
42MP0004084_abnormal_cardiac_muscle1.65246996
43MP0009785_altered_susceptibility_to1.65188800
44MP0000465_gastrointestinal_hemorrhage1.64610018
45MP0010368_abnormal_lymphatic_system1.63879864
46MP0002693_abnormal_pancreas_physiology1.56520725
47MP0002928_abnormal_bile_duct1.56424072
48MP0003045_fibrosis1.55869425
49MP0008260_abnormal_autophagy1.52818834
50MP0003890_abnormal_embryonic-extraembry1.52798911
51MP0001873_stomach_inflammation1.51577458
52MP0008004_abnormal_stomach_pH1.50814013
53MP0005174_abnormal_tail_pigmentation1.47112318
54MP0003221_abnormal_cardiomyocyte_apopto1.45741170
55MP0000716_abnormal_immune_system1.45150406
56MP0005025_abnormal_response_to1.44075819
57MP0005408_hypopigmentation1.43378880
58MP0003724_increased_susceptibility_to1.43185508
59MP0002998_abnormal_bone_remodeling1.39500298
60MP0002095_abnormal_skin_pigmentation1.36758446
61MP0003436_decreased_susceptibility_to1.34033346
62MP0000703_abnormal_thymus_morphology1.33931444
63MP0003943_abnormal_hepatobiliary_system1.30692489
64MP0005164_abnormal_response_to1.29023160
65MP0010155_abnormal_intestine_physiology1.28270779
66MP0004142_abnormal_muscle_tone1.26069610
67MP0000371_diluted_coat_color1.21664704
68MP0005464_abnormal_platelet_physiology1.19871335
69MP0003252_abnormal_bile_duct1.19778220
70MP0005397_hematopoietic_system_phenotyp1.18323379
71MP0001545_abnormal_hematopoietic_system1.18323379
72MP0001944_abnormal_pancreas_morphology1.17237575
73MP0005075_abnormal_melanosome_morpholog1.17199607
74MP0004381_abnormal_hair_follicle1.15064327
75MP0002332_abnormal_exercise_endurance1.14229724
76MP0005187_abnormal_penis_morphology1.13434276
77MP0002405_respiratory_system_inflammati1.13192899
78MP0003866_abnormal_defecation1.12249382
79MP0002148_abnormal_hypersensitivity_rea1.12189547
80MP0002722_abnormal_immune_system1.08289154
81MP0003121_genomic_imprinting1.08225067
82MP0000689_abnormal_spleen_morphology1.05907969
83MP0004134_abnormal_chest_morphology1.03989546
84MP0006054_spinal_hemorrhage1.03487994
85MP0002429_abnormal_blood_cell1.03344226
86MP0004947_skin_inflammation1.02409286
87MP0001845_abnormal_inflammatory_respons0.99162540
88MP0010678_abnormal_skin_adnexa0.97180881
89MP0001188_hyperpigmentation0.96889649
90MP0003868_abnormal_feces_composition0.96450835
91MP0000858_altered_metastatic_potential0.96188206
92MP0002102_abnormal_ear_morphology0.96160488
93MP0001186_pigmentation_phenotype0.94373481
94MP0004036_abnormal_muscle_relaxation0.93629224
95MP0002933_joint_inflammation0.92305952
96MP0001851_eye_inflammation0.91033365
97MP0002075_abnormal_coat/hair_pigmentati0.90818653
98MP0005248_abnormal_Harderian_gland0.90066476
99MP0001853_heart_inflammation0.88936789
100MP0004215_abnormal_myocardial_fiber0.85540389
101MP0005220_abnormal_exocrine_pancreas0.85217298
102MP0000778_abnormal_nervous_system0.85179364
103MP0000383_abnormal_hair_follicle0.84705615
104MP0002177_abnormal_outer_ear0.84293445
105MP0002127_abnormal_cardiovascular_syste0.81834017
106MP0003795_abnormal_bone_structure0.80982466
107MP0003632_abnormal_nervous_system0.80128892
108MP0002168_other_aberrant_phenotype0.80097699
109MP0003091_abnormal_cell_migration0.78004474
110MP0001958_emphysema0.77707860
111MP0004147_increased_porphyrin_level0.77231600
112MP0002234_abnormal_pharynx_morphology0.76352677
113MP0002909_abnormal_adrenal_gland0.75450093
114MP0002067_abnormal_sensory_capabilities0.75263727
115MP0002638_abnormal_pupillary_reflex0.74277931
116MP0002133_abnormal_respiratory_system0.73029005
117MP0005388_respiratory_system_phenotype0.73029005
118MP0001299_abnormal_eye_distance/0.72126630
119MP0004145_abnormal_muscle_electrophysio0.71854676
120MP0000372_irregular_coat_pigmentation0.70760105
121MP0000767_abnormal_smooth_muscle0.70686171
122MP0002837_dystrophic_cardiac_calcinosis0.70501629
123MP0001533_abnormal_skeleton_physiology0.70032516
124MP0004924_abnormal_behavior0.69542339
125MP0005386_behavior/neurological_phenoty0.69542339
126MP0001784_abnormal_fluid_regulation0.68532447
127MP0004484_altered_response_of0.68335642
128MP0003279_aneurysm0.67946076
129MP0009115_abnormal_fat_cell0.67432990
130MP0005076_abnormal_cell_differentiation0.66996630
131MP0005310_abnormal_salivary_gland0.65935372
132MP0002925_abnormal_cardiovascular_devel0.65461844
133MP0006276_abnormal_autonomic_nervous0.65288079
134MP0000733_abnormal_muscle_development0.63731255
135MP0008569_lethality_at_weaning0.63525579
136MP0010352_gastrointestinal_tract_polyps0.63107925
137MP0005266_abnormal_metabolism0.63046396
138MP0009764_decreased_sensitivity_to0.61841868
139MP0005253_abnormal_eye_physiology0.59938660
140MP0001919_abnormal_reproductive_system0.59634559
141MP0003631_nervous_system_phenotype0.58027728
142MP0002971_abnormal_brown_adipose0.57253800

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of the right ventricle (HP:0001707)4.25800533
2Decreased circulating renin level (HP:0003351)4.14323984
3Prostate neoplasm (HP:0100787)4.04499091
4Abnormality of the fingertips (HP:0001211)3.88136060
5Thyroiditis (HP:0100646)3.50990324
6T lymphocytopenia (HP:0005403)3.32829454
7Subaortic stenosis (HP:0001682)3.18603863
8Abnormality of the left ventricular outflow tract (HP:0011103)3.18603863
9Abnormality of T cell number (HP:0011839)3.17505543
10Hypoplastic labia majora (HP:0000059)3.13597927
11Hyperventilation (HP:0002883)3.11578988
12Abnormal hair whorl (HP:0010721)3.06929311
13Hypoplasia of the thymus (HP:0000778)3.05015737
14Curly hair (HP:0002212)2.94623071
15Genetic anticipation (HP:0003743)2.87574783
16Abnormality of B cell number (HP:0010975)2.78978028
17B lymphocytopenia (HP:0010976)2.78978028
18Abnormality of the prostate (HP:0008775)2.78426973
19Cystic hygroma (HP:0000476)2.78339104
20Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.73769618
21Abnormality of the labia majora (HP:0012881)2.73489652
22Thyroid carcinoma (HP:0002890)2.73487307
23Severe combined immunodeficiency (HP:0004430)2.72122615
24Recurrent fungal infections (HP:0002841)2.71961179
25Volvulus (HP:0002580)2.66326029
26Abnormal delayed hypersensitivity skin test (HP:0002963)2.62050671
27Gingival bleeding (HP:0000225)2.58685787
28Recurrent viral infections (HP:0004429)2.57843716
29Myositis (HP:0100614)2.55673770
30Neoplasm of the tracheobronchial system (HP:0100552)2.55582350
31Narrow palate (HP:0000189)2.51771667
32Elevated erythrocyte sedimentation rate (HP:0003565)2.50122617
33Truncal obesity (HP:0001956)2.47756946
34Lip pit (HP:0100267)2.46010015
35Panhypogammaglobulinemia (HP:0003139)2.40567697
36Peritonitis (HP:0002586)2.38287610
37Chronic diarrhea (HP:0002028)2.38203925
38Impaired proprioception (HP:0010831)2.38187708
39Smooth philtrum (HP:0000319)2.34680580
40Optic neuritis (HP:0100653)2.33851376
41Retrobulbar optic neuritis (HP:0100654)2.33851376
42Absent speech (HP:0001344)2.33691878
43Recurrent abscess formation (HP:0002722)2.33638065
44Degeneration of the lateral corticospinal tracts (HP:0002314)2.31467822
45Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.31467822
46Deep philtrum (HP:0002002)2.31114252
47Febrile seizures (HP:0002373)2.29403840
48Absent frontal sinuses (HP:0002688)2.29040543
49Eczematoid dermatitis (HP:0000976)2.27656514
50Spontaneous hematomas (HP:0007420)2.27542225
51Chronic otitis media (HP:0000389)2.24933647
52Recurrent cutaneous fungal infections (HP:0011370)2.23665840
53Chronic mucocutaneous candidiasis (HP:0002728)2.23665840
54Overgrowth (HP:0001548)2.21407201
55Increased density of long bones (HP:0006392)2.18991283
56Acute myeloid leukemia (HP:0004808)2.18984239
57Patent foramen ovale (HP:0001655)2.18010945
58Subacute progressive viral hepatitis (HP:0006572)2.17505100
59Increased number of teeth (HP:0011069)2.17375933
60Eosinophilia (HP:0001880)2.16395377
61Abnormality of incisor morphology (HP:0011063)2.14962801
62Macroorchidism (HP:0000053)2.13532329
63Short chin (HP:0000331)2.13393546
64Chest pain (HP:0100749)2.12933999
65Heterotopia (HP:0002282)2.11147041
66Generalized hypopigmentation of hair (HP:0011358)2.10556943
67Abnormality of the renal cortex (HP:0011035)2.09527315
68Mediastinal lymphadenopathy (HP:0100721)2.08978544
69Alveolar cell carcinoma (HP:0006519)2.07852392
70Abnormality of T cells (HP:0002843)2.07700792
71Menstrual irregularities (HP:0000858)2.07698907
72Frequent falls (HP:0002359)2.07258883
73Submucous cleft hard palate (HP:0000176)2.06742707
74Arterial thrombosis (HP:0004420)2.02179882
75Progressive cerebellar ataxia (HP:0002073)2.00967862
76Stomach cancer (HP:0012126)2.00861418
77Recurrent bronchitis (HP:0002837)2.00033479
78Spinal cord lesions (HP:0100561)1.99963776
79Syringomyelia (HP:0003396)1.99963776
80Abnormality of the nasal septum (HP:0000419)1.96955425
81Orchitis (HP:0100796)1.95791694
82Symptomatic seizures (HP:0011145)1.93704475
83IgG deficiency (HP:0004315)1.93460398
84IgA deficiency (HP:0002720)1.93101374
85Aortic regurgitation (HP:0001659)1.92830496
86Protruding tongue (HP:0010808)1.92698402
87Meningitis (HP:0001287)1.92072944
88Tubulointerstitial nephritis (HP:0001970)1.91766939
89Progressive sensorineural hearing impairment (HP:0000408)1.91760479
90Prominent nose (HP:0000448)1.90888915
91Gaze-evoked nystagmus (HP:0000640)1.90619256
92Ureteral obstruction (HP:0006000)1.90064354
93Facial diplegia (HP:0001349)1.89689910
94Hematochezia (HP:0002573)1.89427480
95Stomatitis (HP:0010280)1.88698803
96Hypoglycemic seizures (HP:0002173)1.87575046
97Keratoconjunctivitis sicca (HP:0001097)1.86997817
98Wide nose (HP:0000445)1.86919003
99Increased mean platelet volume (HP:0011877)1.86770751
100Abnormal platelet volume (HP:0011876)1.86639025
101Abnormality of the metopic suture (HP:0005556)1.85811859
102Postural instability (HP:0002172)1.85599679
103Drooling (HP:0002307)1.85261178
104Widely spaced teeth (HP:0000687)1.85142722
105Pancreatic islet-cell hyperplasia (HP:0004510)1.85069372
106IgM deficiency (HP:0002850)1.85021010
107Abnormality of eosinophils (HP:0001879)1.84135471
108Pulmonary infiltrates (HP:0002113)1.83980090
109Combined immunodeficiency (HP:0005387)1.83897715
110Abnormality of the corticospinal tract (HP:0002492)1.82399140
111Recurrent bacterial skin infections (HP:0005406)1.82360369
112Pancreatic cysts (HP:0001737)1.82158112
113Excessive salivation (HP:0003781)1.81805282
114Long clavicles (HP:0000890)1.81636619
115Hypochromic microcytic anemia (HP:0004840)1.81392717
116Periodontitis (HP:0000704)1.80265452
117Papillary thyroid carcinoma (HP:0002895)1.80086424
118Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.80085358
119Prolonged bleeding time (HP:0003010)1.79975266
120Long eyelashes (HP:0000527)1.79264096
121Blue irides (HP:0000635)1.78623661
122Autoimmune hemolytic anemia (HP:0001890)1.78279534
123Fair hair (HP:0002286)1.76279996
124Sandal gap (HP:0001852)1.76274057
125Epistaxis (HP:0000421)1.75817918
126Inflammation of the large intestine (HP:0002037)1.75414105
127Hip dysplasia (HP:0001385)1.75351448
128Gastrointestinal infarctions (HP:0005244)1.75170292
129Tapered finger (HP:0001182)1.74934852
130Gingivitis (HP:0000230)1.74902742
131Keratoconjunctivitis (HP:0001096)1.74823306
132Coarse hair (HP:0002208)1.74686376
133Leukocytosis (HP:0001974)1.74075660
134Abnormality of the epiphyses of the phalanges of the hand (HP:0005920)1.73839396
135Exostoses (HP:0100777)1.73585616
136Granulocytopenia (HP:0001913)1.73314494
137Birth length less than 3rd percentile (HP:0003561)1.73253986
138Spondylolisthesis (HP:0003302)1.71841305
139Hemoptysis (HP:0002105)1.71799463
140Renal cortical cysts (HP:0000803)1.71730648
141Vasculitis (HP:0002633)1.71573406
142Ureteral stenosis (HP:0000071)1.70539872
143Viral hepatitis (HP:0006562)1.69514549
144Low anterior hairline (HP:0000294)1.68703394
145Oligodactyly (hands) (HP:0001180)1.68392713
146Neoplasm of the adrenal cortex (HP:0100641)1.68322491
147Abnormality of the ischium (HP:0003174)1.67804237
148Hypoplasia of the maxilla (HP:0000327)1.67440626
149Lower limb muscle weakness (HP:0007340)1.66041347
150Cubitus valgus (HP:0002967)1.60837315
151Hypoplastic nipples (HP:0002557)1.60754193
152Difficulty running (HP:0009046)1.60064434
153Short foot (HP:0001773)1.59911909
154Broad ribs (HP:0000885)1.59900304

Predicted kinase interactions (KEA)

RankGene SetZ-score
1INSRR3.91508237
2AKT33.32218158
3TXK2.94249934
4IRAK42.69524367
5MAP4K12.34227212
6TNIK2.11790556
7FRK2.08289241
8JAK32.07100665
9MAP3K142.05931639
10BMPR1B2.03969905
11PIK3CG1.93511533
12FGFR31.91069072
13ITK1.76350339
14TAOK31.72137553
15BRSK21.70383666
16ACVR1B1.64878849
17MAP3K41.64338670
18IKBKE1.63572456
19JAK11.61037839
20PRKCH1.60272318
21NUAK11.59465918
22CAMK1G1.55213413
23MAP3K21.55113172
24TEC1.49229905
25FGFR21.48235230
26SGK21.42558421
27CSK1.40485871
28TTN1.37623260
29SIK21.36469173
30PINK11.35273565
31TNK21.33537972
32KSR11.33063093
33IRAK31.32499965
34MUSK1.32243728
35FES1.31192822
36NLK1.30980607
37YES11.30407311
38TRPM71.29731831
39BMPR21.29175267
40SGK31.28785710
41ZAP701.28698683
42HIPK21.28499597
43MAP2K41.28322565
44MAP3K61.27972763
45PTK61.27331988
46TYK21.26301457
47CDK121.25018716
48LATS11.24282697
49TGFBR21.19613449
50BTK1.17431586
51PASK1.15955502
52PAK31.12821225
53CHUK1.12360450
54ERBB31.08811888
55IRAK11.06243485
56BLK1.04781968
57KIT1.04474705
58LCK1.04326168
59PRKCQ1.04107889
60STK38L0.99401844
61PDGFRB0.99219214
62ZAK0.97265314
63FGFR40.97244158
64HCK0.96980552
65RIPK40.96183340
66EIF2AK30.94151680
67SYK0.93696255
68CAMKK20.93225908
69CAMK1D0.92071662
70PRKD20.91493178
71TBK10.91138250
72CASK0.89876229
73PNCK0.88852261
74MAP2K70.88770032
75MKNK20.87424683
76NEK90.84483357
77PIK3CA0.83924007
78SIK30.81532938
79BRD40.80560222
80STK30.77180071
81PLK20.74415264
82IRAK20.74008637
83PTK2B0.73842433
84CSNK1A1L0.73746901
85STK110.72694191
86PDGFRA0.71674371
87DMPK0.71646963
88OBSCN0.71346335
89MAP3K70.69521278
90JAK20.68922725
91WNK10.66520055
92STK240.66442551
93IKBKB0.65063768
94LYN0.63266632
95MKNK10.62610353
96CAMKK10.62106824
97WNK30.60988206
98EPHA30.59120888
99STK100.58754972
100BCR0.58111115
101RAF10.57980845
102MAP2K30.57821956
103RET0.57110302
104SGK10.56810403
105CDK60.56295278
106IGF1R0.56271537
107ERBB20.55305691
108SGK4940.54896477
109SGK2230.54896477
110ADRBK10.54710006
111GRK60.54328653
112RPS6KB10.54251643
113MARK30.54179469
114CAMK40.52796400
115RPS6KA20.52687182
116STK390.51529365
117TIE10.51036150
118PIM10.50903807
119DYRK30.50707788
120ABL10.48437692
121DYRK1A0.47760078
122MAP3K130.47696603
123CDK30.47551960
124RIPK10.46483876
125ADRBK20.46044139
126MARK10.45607129
127CSF1R0.45319151
128SCYL20.45182376
129PRKAA20.45068845
130PKN20.44160664
131MAPK130.44069961
132FGR0.44050231
133NTRK30.43817395
134CAMK10.43215650
135EPHB10.43080651
136MAP3K50.42659537
137STK40.42607544
138MARK20.42117563
139TAF10.40889268
140FLT30.40356875
141PRKCE0.40180523
142PRKD10.38669953
143INSR0.38154673

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary immunodeficiency_Homo sapiens_hsa053402.45387152
2NF-kappa B signaling pathway_Homo sapiens_hsa040641.97639763
3T cell receptor signaling pathway_Homo sapiens_hsa046601.89243529
4Measles_Homo sapiens_hsa051621.77161395
5Type II diabetes mellitus_Homo sapiens_hsa049301.70414233
6Osteoclast differentiation_Homo sapiens_hsa043801.68972077
7B cell receptor signaling pathway_Homo sapiens_hsa046621.64150962
8Leishmaniasis_Homo sapiens_hsa051401.63080256
9Maturity onset diabetes of the young_Homo sapiens_hsa049501.61773130
10Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.60917823
11Renal cell carcinoma_Homo sapiens_hsa052111.59696374
12Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.57768333
13Intestinal immune network for IgA production_Homo sapiens_hsa046721.40323065
14Hematopoietic cell lineage_Homo sapiens_hsa046401.37995778
15Platelet activation_Homo sapiens_hsa046111.32845846
16Carbohydrate digestion and absorption_Homo sapiens_hsa049731.29603107
17Toll-like receptor signaling pathway_Homo sapiens_hsa046201.28041454
18Lysine degradation_Homo sapiens_hsa003101.26872801
19Jak-STAT signaling pathway_Homo sapiens_hsa046301.26456139
20NOD-like receptor signaling pathway_Homo sapiens_hsa046211.25635935
21Long-term depression_Homo sapiens_hsa047301.25122551
22Leukocyte transendothelial migration_Homo sapiens_hsa046701.23330814
23Chemokine signaling pathway_Homo sapiens_hsa040621.23005862
24Phosphatidylinositol signaling system_Homo sapiens_hsa040701.22512064
25Insulin secretion_Homo sapiens_hsa049111.21585506
26Toxoplasmosis_Homo sapiens_hsa051451.18964075
27Prolactin signaling pathway_Homo sapiens_hsa049171.16050221
28Viral myocarditis_Homo sapiens_hsa054161.14931909
29TNF signaling pathway_Homo sapiens_hsa046681.14767196
30Glioma_Homo sapiens_hsa052141.14242140
31Regulation of autophagy_Homo sapiens_hsa041401.14175977
32Transcriptional misregulation in cancer_Homo sapiens_hsa052021.11621080
33Aldosterone synthesis and secretion_Homo sapiens_hsa049251.09014864
34RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.08588431
35Allograft rejection_Homo sapiens_hsa053301.07497314
36Renin secretion_Homo sapiens_hsa049241.07017559
37ErbB signaling pathway_Homo sapiens_hsa040121.01878962
38Insulin resistance_Homo sapiens_hsa049310.99984157
39Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.99141033
40Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.99122739
41Prostate cancer_Homo sapiens_hsa052150.98910724
42Antigen processing and presentation_Homo sapiens_hsa046120.98797551
43Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.96802870
44Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.96233615
45Chronic myeloid leukemia_Homo sapiens_hsa052200.95185297
46Adherens junction_Homo sapiens_hsa045200.93715129
47Tuberculosis_Homo sapiens_hsa051520.93673852
48Type I diabetes mellitus_Homo sapiens_hsa049400.93586418
49Herpes simplex infection_Homo sapiens_hsa051680.92924121
50Hepatitis B_Homo sapiens_hsa051610.91803095
51Influenza A_Homo sapiens_hsa051640.90786011
52Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.90555167
53Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.90196001
54Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.89883671
55Focal adhesion_Homo sapiens_hsa045100.89218561
56Dilated cardiomyopathy_Homo sapiens_hsa054140.88504651
57Acute myeloid leukemia_Homo sapiens_hsa052210.88170564
58Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.86838979
59Small cell lung cancer_Homo sapiens_hsa052220.86784362
60Endometrial cancer_Homo sapiens_hsa052130.86641239
61Circadian entrainment_Homo sapiens_hsa047130.86621181
62AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.86600341
63Cholinergic synapse_Homo sapiens_hsa047250.85562784
64Graft-versus-host disease_Homo sapiens_hsa053320.85333680
65Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.84510474
66Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.84300252
67Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.83166911
68Shigellosis_Homo sapiens_hsa051310.82540101
69Autoimmune thyroid disease_Homo sapiens_hsa053200.82093376
70mTOR signaling pathway_Homo sapiens_hsa041500.82091010
71Serotonergic synapse_Homo sapiens_hsa047260.81718431
72Thyroid hormone signaling pathway_Homo sapiens_hsa049190.81248209
73cAMP signaling pathway_Homo sapiens_hsa040240.80435021
74Hepatitis C_Homo sapiens_hsa051600.78432978
75VEGF signaling pathway_Homo sapiens_hsa043700.78308902
76Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.77964421
77FoxO signaling pathway_Homo sapiens_hsa040680.77782894
78Glutamatergic synapse_Homo sapiens_hsa047240.77459928
79Regulation of actin cytoskeleton_Homo sapiens_hsa048100.77422809
80Dopaminergic synapse_Homo sapiens_hsa047280.77421406
81cGMP-PKG signaling pathway_Homo sapiens_hsa040220.77330899
82Gap junction_Homo sapiens_hsa045400.77019212
83Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.76872925
84Choline metabolism in cancer_Homo sapiens_hsa052310.76458951
85Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.75985285
86Long-term potentiation_Homo sapiens_hsa047200.75939859
87Melanoma_Homo sapiens_hsa052180.74425867
88Pancreatic cancer_Homo sapiens_hsa052120.74261807
89Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.74104696
90Axon guidance_Homo sapiens_hsa043600.72194076
91Estrogen signaling pathway_Homo sapiens_hsa049150.71126868
92HTLV-I infection_Homo sapiens_hsa051660.70465344
93Colorectal cancer_Homo sapiens_hsa052100.70237303
94Neurotrophin signaling pathway_Homo sapiens_hsa047220.69462932
95Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.69388801
96Inositol phosphate metabolism_Homo sapiens_hsa005620.68647565
97Malaria_Homo sapiens_hsa051440.67624283
98Oxytocin signaling pathway_Homo sapiens_hsa049210.67509622
99Proteoglycans in cancer_Homo sapiens_hsa052050.67030843
100Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.65870789
101Vascular smooth muscle contraction_Homo sapiens_hsa042700.65854344
102Legionellosis_Homo sapiens_hsa051340.65815275
103MAPK signaling pathway_Homo sapiens_hsa040100.65433005
104Phospholipase D signaling pathway_Homo sapiens_hsa040720.65385338
105Rap1 signaling pathway_Homo sapiens_hsa040150.65213962
106Adipocytokine signaling pathway_Homo sapiens_hsa049200.64908062
107Longevity regulating pathway - mammal_Homo sapiens_hsa042110.64574074
108Ras signaling pathway_Homo sapiens_hsa040140.64457889
109MicroRNAs in cancer_Homo sapiens_hsa052060.64185690
110Pertussis_Homo sapiens_hsa051330.62559677
111Pathways in cancer_Homo sapiens_hsa052000.62408210
112Calcium signaling pathway_Homo sapiens_hsa040200.62318376
113Morphine addiction_Homo sapiens_hsa050320.62282182
114Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.62054250
115ABC transporters_Homo sapiens_hsa020100.61717260
116GnRH signaling pathway_Homo sapiens_hsa049120.61591143
117Non-small cell lung cancer_Homo sapiens_hsa052230.60953695
118Sphingolipid signaling pathway_Homo sapiens_hsa040710.60553605
119Alcoholism_Homo sapiens_hsa050340.60514554
120Circadian rhythm_Homo sapiens_hsa047100.60349444
121Olfactory transduction_Homo sapiens_hsa047400.59969083
122Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.59290952
123Salmonella infection_Homo sapiens_hsa051320.57778550
124Dorso-ventral axis formation_Homo sapiens_hsa043200.57190234
125Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.56924222
126Taste transduction_Homo sapiens_hsa047420.56191750

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