PHF21B

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1behavioral response to nicotine (GO:0035095)5.21714323
2axonal fasciculation (GO:0007413)4.80758576
3neuron recognition (GO:0008038)4.69887163
4cell migration in hindbrain (GO:0021535)4.63739996
5pyrimidine nucleobase catabolic process (GO:0006208)4.55870417
6establishment of mitochondrion localization (GO:0051654)4.23720581
7layer formation in cerebral cortex (GO:0021819)4.19529242
8central nervous system projection neuron axonogenesis (GO:0021952)4.19374579
9dendritic spine morphogenesis (GO:0060997)4.09677137
10response to pheromone (GO:0019236)3.85896156
11establishment of nucleus localization (GO:0040023)3.83263885
12forebrain neuron differentiation (GO:0021879)3.77235438
13dendrite morphogenesis (GO:0048813)3.75624140
14establishment of mitochondrion localization, microtubule-mediated (GO:0034643)3.62172208
15mitochondrion transport along microtubule (GO:0047497)3.62172208
16positive regulation of gastrulation (GO:2000543)3.57823057
17retinal ganglion cell axon guidance (GO:0031290)3.57155863
18cerebral cortex radially oriented cell migration (GO:0021799)3.55240152
19neuron cell-cell adhesion (GO:0007158)3.49171005
20ganglion development (GO:0061548)3.44844087
21limb bud formation (GO:0060174)3.40696524
22positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.40668499
23cerebellum development (GO:0021549)3.37289231
24spinal cord development (GO:0021510)3.33243336
25regulation of short-term neuronal synaptic plasticity (GO:0048172)3.32204327
26hippocampus development (GO:0021766)3.31210913
27presynaptic membrane organization (GO:0097090)3.30536902
28cerebellar Purkinje cell differentiation (GO:0021702)3.30317325
29central nervous system neuron axonogenesis (GO:0021955)3.28832830
30neurofilament cytoskeleton organization (GO:0060052)3.28769027
31protein-DNA complex disassembly (GO:0032986)3.27859892
32nucleosome disassembly (GO:0006337)3.27859892
33cell differentiation in spinal cord (GO:0021515)3.24977473
34body morphogenesis (GO:0010171)3.24766898
35regulation of development, heterochronic (GO:0040034)3.24721680
36postsynaptic membrane organization (GO:0001941)3.24433497
37negative regulation of oligodendrocyte differentiation (GO:0048715)3.23178494
38glial cell proliferation (GO:0014009)3.20868321
39synapse assembly (GO:0007416)3.17625313
40presynaptic membrane assembly (GO:0097105)3.17507639
41embryonic body morphogenesis (GO:0010172)3.16249850
42spinal cord motor neuron differentiation (GO:0021522)3.11591010
43cerebral cortex neuron differentiation (GO:0021895)3.11564958
44nucleobase catabolic process (GO:0046113)3.11055533
45protein localization to synapse (GO:0035418)3.10109432
46vocalization behavior (GO:0071625)3.09528754
47regulation of timing of cell differentiation (GO:0048505)3.09419729
48negative regulation of axon extension involved in axon guidance (GO:0048843)3.06225305
49endocrine pancreas development (GO:0031018)3.05183831
50regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.03037499
51negative regulation of axon extension (GO:0030517)2.99656312
52nonmotile primary cilium assembly (GO:0035058)2.99509185
53regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.96268966
54olfactory bulb development (GO:0021772)2.96210362
55somite development (GO:0061053)2.95109541
56regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.94356962
57spinal cord association neuron differentiation (GO:0021527)2.94173261
58central nervous system neuron differentiation (GO:0021953)2.93450340
59negative regulation of axon guidance (GO:1902668)2.92927093
60hindbrain development (GO:0030902)2.92908414
61axon extension (GO:0048675)2.92493128
62neuromuscular synaptic transmission (GO:0007274)2.89163594
63primitive streak formation (GO:0090009)2.87745966
64neuronal stem cell maintenance (GO:0097150)2.86962152
65head development (GO:0060322)2.86508245
66histone H3-K4 trimethylation (GO:0080182)2.86445700
67protein polyglutamylation (GO:0018095)2.86388485
68cranial nerve morphogenesis (GO:0021602)2.85471616
69axon extension involved in axon guidance (GO:0048846)2.84476495
70neuron projection extension involved in neuron projection guidance (GO:1902284)2.84476495
71mRNA splice site selection (GO:0006376)2.84452948
72calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.84245140
73neuron fate determination (GO:0048664)2.84200010
74positive regulation of dendritic spine morphogenesis (GO:0061003)2.82607681
75sympathetic nervous system development (GO:0048485)2.82284462
76cell differentiation in hindbrain (GO:0021533)2.82219118
77mechanosensory behavior (GO:0007638)2.82202810
78camera-type eye morphogenesis (GO:0048593)2.82097693
79nucleus localization (GO:0051647)2.81820126
80neuron migration (GO:0001764)2.81327245
81eye photoreceptor cell differentiation (GO:0001754)2.81277256
82photoreceptor cell differentiation (GO:0046530)2.81277256
83ephrin receptor signaling pathway (GO:0048013)2.77641154
84glandular epithelial cell differentiation (GO:0002067)2.75750651
85epithelial cell fate commitment (GO:0072148)2.75430294
86axonogenesis (GO:0007409)2.75067520
87transmission of nerve impulse (GO:0019226)2.74914149
88positive regulation of synapse assembly (GO:0051965)2.73559829
89negative regulation of axonogenesis (GO:0050771)2.73128262
90lateral sprouting from an epithelium (GO:0060601)2.72843570
91neuronal ion channel clustering (GO:0045161)2.72775011
92negative regulation of glial cell differentiation (GO:0045686)2.71729468
93retina layer formation (GO:0010842)2.69496955
94regulation of alternative mRNA splicing, via spliceosome (GO:0000381)2.68688569
95behavioral response to ethanol (GO:0048149)2.68383349
96dendrite development (GO:0016358)2.67126584
97ionotropic glutamate receptor signaling pathway (GO:0035235)2.66083128
98urogenital system development (GO:0001655)2.65600246
99neurotransmitter-gated ion channel clustering (GO:0072578)2.64965260
100negative regulation of translation, ncRNA-mediated (GO:0040033)2.64465777
101regulation of translation, ncRNA-mediated (GO:0045974)2.64465777
102negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.64465777
103adult walking behavior (GO:0007628)2.64427153
104stress granule assembly (GO:0034063)2.64008688
105dopaminergic neuron differentiation (GO:0071542)2.63538362
106positive regulation of RNA splicing (GO:0033120)2.63076662
107regulation of mRNA splicing, via spliceosome (GO:0048024)2.62503148
108positive regulation of intracellular steroid hormone receptor signaling pathway (GO:0033145)2.62474651
109regulation of neuron migration (GO:2001222)2.59154486
110positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.58159602
111negative regulation of microtubule polymerization (GO:0031115)2.58066240
112auditory behavior (GO:0031223)2.57252478
113positive regulation of excitatory postsynaptic membrane potential (GO:2000463)2.56066078
114cell proliferation in forebrain (GO:0021846)2.55977417
115dendritic spine organization (GO:0097061)2.55973581
116astrocyte differentiation (GO:0048708)2.55959287
117locomotory exploration behavior (GO:0035641)2.55344896
118synaptic transmission, cholinergic (GO:0007271)2.54530136
119synaptic transmission, glutamatergic (GO:0035249)2.53805987
120regulation of oligodendrocyte differentiation (GO:0048713)2.53086412
121regulation of respiratory system process (GO:0044065)2.52650599
122neuron projection morphogenesis (GO:0048812)2.52523395
123negative chemotaxis (GO:0050919)2.50156979
124negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.49900807
125cranial nerve development (GO:0021545)2.49432202
126regulation of posttranscriptional gene silencing (GO:0060147)2.48549535
127regulation of gene silencing by miRNA (GO:0060964)2.48549535
128regulation of gene silencing by RNA (GO:0060966)2.48549535
129regulation of axon guidance (GO:1902667)2.48518510
130forebrain development (GO:0030900)2.48184065
131substrate-independent telencephalic tangential interneuron migration (GO:0021843)2.47782492
132substrate-independent telencephalic tangential migration (GO:0021826)2.47782492
133synapse organization (GO:0050808)2.47642487
134midbrain development (GO:0030901)2.46946791
135adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)2.44562668
136regulation of synapse structural plasticity (GO:0051823)2.44364272
137neuron fate specification (GO:0048665)2.42633050
138short-term memory (GO:0007614)2.42604080
139regulation of cilium movement (GO:0003352)2.42120114
140exploration behavior (GO:0035640)2.41128267
141regulation of microtubule-based movement (GO:0060632)2.41121386
142intraciliary transport (GO:0042073)2.40966937
143kidney morphogenesis (GO:0060993)2.37466365
144positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.36627638
145paraxial mesoderm development (GO:0048339)2.35985724

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1* EZH2_22144423_ChIP-Seq_EOC_Human4.57140070
2EZH2_27304074_Chip-Seq_ESCs_Mouse3.22815116
3RBPJ_22232070_ChIP-Seq_NCS_Mouse3.08043156
4NR4A2_19515692_ChIP-ChIP_MN9D_Mouse3.00638068
5JARID2_20064375_ChIP-Seq_MESCs_Mouse2.85821090
6JARID2_20075857_ChIP-Seq_MESCs_Mouse2.64989544
7TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.58471189
8RNF2_18974828_ChIP-Seq_MESCs_Mouse2.57440763
9EZH2_18974828_ChIP-Seq_MESCs_Mouse2.57440763
10EZH2_27294783_Chip-Seq_ESCs_Mouse2.55908582
11SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.49967410
12SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.43654294
13RNF2_27304074_Chip-Seq_ESCs_Mouse2.42268973
14CBX2_27304074_Chip-Seq_ESCs_Mouse2.37353745
15EED_16625203_ChIP-ChIP_MESCs_Mouse2.36986162
16* EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.36930442
17* SUZ12_27294783_Chip-Seq_ESCs_Mouse2.35770371
18* REST_21632747_ChIP-Seq_MESCs_Mouse2.34533725
19CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.30580327
20GBX2_23144817_ChIP-Seq_PC3_Human2.27116827
21OLIG2_26023283_ChIP-Seq_AINV15_Mouse2.22429828
22SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.18525910
23SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.17347144
24STAT6_21828071_ChIP-Seq_BEAS2B_Human2.13735355
25PHC1_16625203_ChIP-ChIP_MESCs_Mouse2.12143125
26GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.10944560
27* RING1B_27294783_Chip-Seq_NPCs_Mouse2.08178744
28EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse2.04051696
29HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.00238805
30REST_18959480_ChIP-ChIP_MESCs_Mouse1.98402073
31ZFP281_18757296_ChIP-ChIP_E14_Mouse1.96206911
32DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.95235533
33SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.93028658
34* SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.88612466
35RNF2_27304074_Chip-Seq_NSC_Mouse1.86974287
36DROSHA_22980978_ChIP-Seq_HELA_Human1.85030871
37RARB_27405468_Chip-Seq_BRAIN_Mouse1.82793654
38RING1B_27294783_Chip-Seq_ESCs_Mouse1.82550563
39RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.80794046
40MTF2_20144788_ChIP-Seq_MESCs_Mouse1.80211183
41BMI1_23680149_ChIP-Seq_NPCS_Mouse1.71574097
42TP63_19390658_ChIP-ChIP_HaCaT_Human1.70405195
43* ZFP281_27345836_Chip-Seq_ESCs_Mouse1.65700092
44TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.63771379
45WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.61434133
46POU5F1_16153702_ChIP-ChIP_HESCs_Human1.58623137
47ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.57468463
48* KDM2B_26808549_Chip-Seq_K562_Human1.52924294
49HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.52907051
50ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.52828237
51TP53_20018659_ChIP-ChIP_R1E_Mouse1.52274066
52GATA1_26923725_Chip-Seq_HPCs_Mouse1.51524800
53ERG_21242973_ChIP-ChIP_JURKAT_Human1.51342822
54PKCTHETA_26484144_Chip-Seq_BREAST_Human1.48257949
55TAF15_26573619_Chip-Seq_HEK293_Human1.45316127
56ZFP57_27257070_Chip-Seq_ESCs_Mouse1.44977509
57TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.37468057
58CTBP2_25329375_ChIP-Seq_LNCAP_Human1.35771425
59SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.34520017
60MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.34028094
61ZNF274_21170338_ChIP-Seq_K562_Hela1.31843657
62ISL1_27105846_Chip-Seq_CPCs_Mouse1.29581741
63PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.28451346
64CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.23966958
65DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.23237995
66P300_19829295_ChIP-Seq_ESCs_Human1.23087582
67SALL1_21062744_ChIP-ChIP_HESCs_Human1.22159819
68SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.22034113
69* RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.21914102
70IRF1_19129219_ChIP-ChIP_H3396_Human1.20137333
71EWS_26573619_Chip-Seq_HEK293_Human1.18722630
72IGF1R_20145208_ChIP-Seq_DFB_Human1.18061293
73SOX2_16153702_ChIP-ChIP_HESCs_Human1.17904026
74KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.17560210
75MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.15703823
76CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse1.14502293
77* TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.14395515
78* POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.14395515
79CTBP1_25329375_ChIP-Seq_LNCAP_Human1.11267538
80SOX3_22085726_ChIP-Seq_NPCs_Mouse1.10224619
81CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.09148002
82TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.08935808
83KDM2B_26808549_Chip-Seq_JURKAT_Human1.06846570
84SOX2_18555785_ChIP-Seq_MESCs_Mouse1.06815707
85* POU3F1_26484290_ChIP-Seq_ESCss_Mouse1.06757219
86WT1_25993318_ChIP-Seq_PODOCYTE_Human1.05919873
87SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.03965220
88TOP2B_26459242_ChIP-Seq_MCF-7_Human1.03524458
89* YAP1_20516196_ChIP-Seq_MESCs_Mouse1.02534182
90SMAD3_21741376_ChIP-Seq_EPCs_Human1.01245334
91* AR_19668381_ChIP-Seq_PC3_Human1.01076831
92FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.00858404
93AR_21572438_ChIP-Seq_LNCaP_Human1.00716824
94GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.00476383
95IKZF1_21737484_ChIP-ChIP_HCT116_Human1.00323886
96HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human0.99469309
97GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.99427179
98CTCF_27219007_Chip-Seq_Bcells_Human0.99249221
99ZIC3_20872845_ChIP-ChIP_MESCs_Mouse0.98959625
100SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.98700505
101POU5F1_18347094_ChIP-ChIP_MESCs_Mouse0.98255258
102FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.96381512
103* RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.96086002
104MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.96073426
105* SOX2_21211035_ChIP-Seq_LN229_Gbm0.95940543
106SMAD4_21799915_ChIP-Seq_A2780_Human0.94096598
107MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.93683403
108TCF3_18347094_ChIP-ChIP_MESCs_Mouse0.92867876
109TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.92374902
110MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human0.92310827
111STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse0.90120323
112CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.90082615
113RUNX2_22187159_ChIP-Seq_PCA_Human0.88937220
114POU3F2_20337985_ChIP-ChIP_501MEL_Human0.88068550
115CREB1_26743006_Chip-Seq_LNCaP_Human0.87980124
116* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.87488271
117P53_22127205_ChIP-Seq_FIBROBLAST_Human0.87385019
118PIAS1_25552417_ChIP-Seq_VCAP_Human0.87255036
119WDR5_24793694_ChIP-Seq_LNCAP_Human0.86918872
120FUS_26573619_Chip-Seq_HEK293_Human0.86627635
121VDR_22108803_ChIP-Seq_LS180_Human0.86294196
122ARNT_22903824_ChIP-Seq_MCF-7_Human0.85781339
123SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.85559244
124* SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.85259875
125* SOX9_26525672_Chip-Seq_HEART_Mouse0.85238613
126SMAD3_21741376_ChIP-Seq_ESCs_Human0.83901301
127OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.83809655

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern3.60112910
2MP0000778_abnormal_nervous_system3.37898111
3MP0002653_abnormal_ependyma_morphology3.37423564
4MP0002822_catalepsy3.26340619
5MP0006292_abnormal_olfactory_placode2.77080796
6MP0004859_abnormal_synaptic_plasticity2.58156147
7MP0006072_abnormal_retinal_apoptosis2.49583604
8MP0006276_abnormal_autonomic_nervous2.36527632
9MP0004270_analgesia2.34298201
10MP0008789_abnormal_olfactory_epithelium2.32606721
11MP0001188_hyperpigmentation2.31684786
12MP0005499_abnormal_olfactory_system2.15512929
13MP0005394_taste/olfaction_phenotype2.15512929
14MP0005423_abnormal_somatic_nervous2.10120606
15MP0003123_paternal_imprinting2.09515167
16MP0001529_abnormal_vocalization2.07242748
17MP0000631_abnormal_neuroendocrine_gland2.02746633
18MP0002638_abnormal_pupillary_reflex2.00312581
19MP0000566_synostosis1.97581327
20MP0003890_abnormal_embryonic-extraembry1.97416232
21MP0010030_abnormal_orbit_morphology1.90325912
22MP0003122_maternal_imprinting1.87796256
23MP0003635_abnormal_synaptic_transmissio1.85540465
24MP0000049_abnormal_middle_ear1.80775820
25MP0000955_abnormal_spinal_cord1.75855894
26MP0002184_abnormal_innervation1.73593197
27MP0003861_abnormal_nervous_system1.73314023
28MP0002751_abnormal_autonomic_nervous1.72322977
29MP0003283_abnormal_digestive_organ1.72261630
30MP0003787_abnormal_imprinting1.71887248
31MP0002063_abnormal_learning/memory/cond1.71848452
32MP0003136_yellow_coat_color1.70011694
33MP0000537_abnormal_urethra_morphology1.69717476
34MP0002735_abnormal_chemical_nociception1.69419561
35MP0002882_abnormal_neuron_morphology1.65437564
36MP0003119_abnormal_digestive_system1.64130469
37MP0005551_abnormal_eye_electrophysiolog1.59152043
38MP0005253_abnormal_eye_physiology1.58136857
39MP0003938_abnormal_ear_development1.56535544
40MP0004133_heterotaxia1.54262652
41MP0005645_abnormal_hypothalamus_physiol1.53529721
42MP0002152_abnormal_brain_morphology1.51891375
43MP0008877_abnormal_DNA_methylation1.51636789
44MP0004142_abnormal_muscle_tone1.50793005
45MP0001502_abnormal_circadian_rhythm1.50752496
46MP0009379_abnormal_foot_pigmentation1.50377725
47MP0002557_abnormal_social/conspecific_i1.48430260
48MP0009780_abnormal_chondrocyte_physiolo1.48129893
49MP0005646_abnormal_pituitary_gland1.47742164
50MP0002909_abnormal_adrenal_gland1.46787627
51MP0004811_abnormal_neuron_physiology1.43872164
52MP0000569_abnormal_digit_pigmentation1.43274413
53MP0004858_abnormal_nervous_system1.42915424
54MP0001984_abnormal_olfaction1.42639504
55MP0004885_abnormal_endolymph1.41859326
56MP0001968_abnormal_touch/_nociception1.40284164
57MP0003121_genomic_imprinting1.38396804
58MP0002734_abnormal_mechanical_nocicepti1.37746712
59MP0001486_abnormal_startle_reflex1.34686728
60MP0002752_abnormal_somatic_nervous1.33869362
61MP0002234_abnormal_pharynx_morphology1.33783213
62MP0001970_abnormal_pain_threshold1.30238452
63MP0002572_abnormal_emotion/affect_behav1.29862097
64MP0002064_seizures1.27020441
65MP0004742_abnormal_vestibular_system1.25099508
66MP0003755_abnormal_palate_morphology1.22675727
67MP0002938_white_spotting1.22314052
68MP0001485_abnormal_pinna_reflex1.20478271
69MP0005391_vision/eye_phenotype1.18906983
70MP0002067_abnormal_sensory_capabilities1.15576606
71MP0002272_abnormal_nervous_system1.15330751
72MP0000026_abnormal_inner_ear1.14875122
73MP0009745_abnormal_behavioral_response1.13847830
74MP0000462_abnormal_digestive_system1.13174379
75MP0005195_abnormal_posterior_eye1.12520016
76MP0002116_abnormal_craniofacial_bone1.12345440
77MP0001440_abnormal_grooming_behavior1.11451203
78MP0002736_abnormal_nociception_after1.09949473
79MP0003935_abnormal_craniofacial_develop1.08291299
80MP0002733_abnormal_thermal_nociception1.08020295
81MP0002102_abnormal_ear_morphology1.07841394
82MP0003942_abnormal_urinary_system1.07106668
83MP0005187_abnormal_penis_morphology1.07011612
84MP0003567_abnormal_fetal_cardiomyocyte1.06724445
85MP0005248_abnormal_Harderian_gland1.06637656
86MP0003183_abnormal_peptide_metabolism1.06479891
87MP0001944_abnormal_pancreas_morphology1.05391265
88MP0003137_abnormal_impulse_conducting1.04647405
89MP0002081_perinatal_lethality1.03931049
90MP0010386_abnormal_urinary_bladder1.03358348
91MP0003315_abnormal_perineum_morphology1.02849188
92MP0001299_abnormal_eye_distance/1.02405910
93MP0003937_abnormal_limbs/digits/tail_de1.02238086
94MP0001286_abnormal_eye_development1.01849014
95MP0008961_abnormal_basal_metabolism1.01075364
96MP0001293_anophthalmia1.00745563
97MP0000428_abnormal_craniofacial_morphol0.99409949
98MP0000534_abnormal_ureter_morphology0.98862641
99MP0005377_hearing/vestibular/ear_phenot0.97102152
100MP0003878_abnormal_ear_physiology0.97102152
101MP0002163_abnormal_gland_morphology0.96460998
102MP0002066_abnormal_motor_capabilities/c0.95785824
103MP0002697_abnormal_eye_size0.94813756
104MP0002233_abnormal_nose_morphology0.94597156
105MP0002069_abnormal_eating/drinking_beha0.91954210
106MP0003385_abnormal_body_wall0.90930590
107MP0008569_lethality_at_weaning0.88802180
108MP0009046_muscle_twitch0.87206499
109MP0008995_early_reproductive_senescence0.86934472
110MP0003115_abnormal_respiratory_system0.86398083
111MP0001346_abnormal_lacrimal_gland0.85423300
112MP0005386_behavior/neurological_phenoty0.84999753
113MP0004924_abnormal_behavior0.84999753
114MP0002229_neurodegeneration0.84945699
115MP0001905_abnormal_dopamine_level0.84561274
116MP0001963_abnormal_hearing_physiology0.83936156
117MP0001324_abnormal_eye_pigmentation0.83130765
118MP0004043_abnormal_pH_regulation0.82043759
119MP0003634_abnormal_glial_cell0.82012975
120MP0002249_abnormal_larynx_morphology0.80203636
121MP0009053_abnormal_anal_canal0.75145013

Predicted human phenotypes

RankGene SetZ-score
1Myokymia (HP:0002411)3.82088068
2Supranuclear gaze palsy (HP:0000605)3.38508645
3Cortical dysplasia (HP:0002539)2.94909246
4Split foot (HP:0001839)2.81542443
5Bony spicule pigmentary retinopathy (HP:0007737)2.75140667
6Hyperacusis (HP:0010780)2.73378786
7Lissencephaly (HP:0001339)2.63450778
8Elfin facies (HP:0004428)2.61533311
9Pendular nystagmus (HP:0012043)2.57073658
10Overriding aorta (HP:0002623)2.55415329
11Pachygyria (HP:0001302)2.51227423
12Insomnia (HP:0100785)2.40957898
13Nephronophthisis (HP:0000090)2.40714552
14Polyphagia (HP:0002591)2.39856103
15High anterior hairline (HP:0009890)2.38665567
16Failure to thrive in infancy (HP:0001531)2.37785338
17Limb dystonia (HP:0002451)2.37638887
18Septo-optic dysplasia (HP:0100842)2.34081994
19Renal duplication (HP:0000075)2.33529654
20Rib fusion (HP:0000902)2.31802117
21Pancreatic fibrosis (HP:0100732)2.31674157
22Abnormal sex determination (HP:0012244)2.28937624
23Sex reversal (HP:0012245)2.28937624
24Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.28008656
25Short 4th metacarpal (HP:0010044)2.28008656
26Anencephaly (HP:0002323)2.26474804
27Cutaneous syndactyly (HP:0012725)2.25078415
28Abnormality of the diencephalon (HP:0010662)2.24596432
29Alacrima (HP:0000522)2.22448935
30Abnormality of the labia minora (HP:0012880)2.21272976
31Shawl scrotum (HP:0000049)2.17636532
32Epileptiform EEG discharges (HP:0011182)2.17021547
33Vaginal atresia (HP:0000148)2.16012534
34Drooling (HP:0002307)2.16003412
35Excessive salivation (HP:0003781)2.16003412
36Hyperthyroidism (HP:0000836)2.15298371
37Epileptic encephalopathy (HP:0200134)2.14842695
38Hypsarrhythmia (HP:0002521)2.13496446
39Patellar aplasia (HP:0006443)2.13373587
40Retinal dysplasia (HP:0007973)2.12126519
41Renovascular hypertension (HP:0100817)2.12057461
42EEG with generalized epileptiform discharges (HP:0011198)2.11961953
43Cutaneous finger syndactyly (HP:0010554)2.11577194
44Absent rod-and cone-mediated responses on ERG (HP:0007688)2.11495359
45Impaired vibration sensation in the lower limbs (HP:0002166)2.11244079
46Genital tract atresia (HP:0001827)2.09941687
47Abnormality of the aortic arch (HP:0012303)2.08968919
48Intestinal atresia (HP:0011100)2.08857456
49Abnormal rod and cone electroretinograms (HP:0008323)2.08792291
50Abnormality of the 4th metacarpal (HP:0010012)2.08473988
51Elevated circulating parathyroid hormone (PTH) level (HP:0003165)2.08458369
52Amblyopia (HP:0000646)2.08148656
53Specific learning disability (HP:0001328)2.06954886
54Medial flaring of the eyebrow (HP:0010747)2.06845793
55Aplasia/Hypoplasia of the optic nerve (HP:0008058)2.06591328
56Anteriorly placed anus (HP:0001545)2.05587689
57Protruding tongue (HP:0010808)2.05529726
58Optic nerve coloboma (HP:0000588)2.05437399
59Truncus arteriosus (HP:0001660)2.04398880
60Hypoplasia of the brainstem (HP:0002365)2.04246028
61Aplasia/Hypoplasia of the brainstem (HP:0007362)2.04246028
62Exotropia (HP:0000577)2.04226666
63Growth hormone deficiency (HP:0000824)2.03863554
64Type II diabetes mellitus (HP:0005978)2.03480149
65True hermaphroditism (HP:0010459)2.02697811
66Chronic hepatic failure (HP:0100626)2.02486845
67Macroorchidism (HP:0000053)2.02190316
68Sclerocornea (HP:0000647)2.01393525
69Abnormality of the metopic suture (HP:0005556)2.01055047
70Megalencephaly (HP:0001355)2.00745698
71Pancreatic cysts (HP:0001737)2.00556603
72Absent septum pellucidum (HP:0001331)2.00338513
73Congenital primary aphakia (HP:0007707)1.98445282
74Anophthalmia (HP:0000528)1.98174822
75Spastic gait (HP:0002064)1.97834962
76Nephrogenic diabetes insipidus (HP:0009806)1.97695622
77Decreased lacrimation (HP:0000633)1.96022114
78Chorioretinal atrophy (HP:0000533)1.95781872
79Maternal diabetes (HP:0009800)1.95669357
80Molar tooth sign on MRI (HP:0002419)1.95472015
81Abnormality of midbrain morphology (HP:0002418)1.95472015
82Aplasia/Hypoplasia of the patella (HP:0006498)1.95016044
83Focal seizures (HP:0007359)1.94017534
84Atelectasis (HP:0100750)1.93371008
85Abnormality of the corticospinal tract (HP:0002492)1.93192869
86Increased nuchal translucency (HP:0010880)1.91820926
87Renal dysplasia (HP:0000110)1.90906424
88Aplasia/Hypoplasia of the sternum (HP:0006714)1.90414063
89Impaired smooth pursuit (HP:0007772)1.90359546
90Agitation (HP:0000713)1.90033023
91Abnormality of the parathyroid morphology (HP:0011766)1.89666422
92Narrow forehead (HP:0000341)1.89528741
93Hyperventilation (HP:0002883)1.89070867
94Spina bifida occulta (HP:0003298)1.89065378
95Abnormality of the renal medulla (HP:0100957)1.88994720
96Intellectual disability, moderate (HP:0002342)1.87897131
97Neoplasm of the heart (HP:0100544)1.87517488
98Hypoplastic female external genitalia (HP:0012815)1.87463902
99Optic nerve hypoplasia (HP:0000609)1.87407379
100Hepatoblastoma (HP:0002884)1.86989778
101Micropenis (HP:0000054)1.86816166
102Attenuation of retinal blood vessels (HP:0007843)1.86612480
103Abnormal number of incisors (HP:0011064)1.86082800
104Abnormality of the lower motor neuron (HP:0002366)1.85131612
105Congenital stationary night blindness (HP:0007642)1.84337991
106Symptomatic seizures (HP:0011145)1.84253637
107Neoplasm of the adrenal cortex (HP:0100641)1.84042377
108Patellar dislocation (HP:0002999)1.81745353
109Obsessive-compulsive behavior (HP:0000722)1.81331977
110Renal hypoplasia (HP:0000089)1.81075767
111Esophageal atresia (HP:0002032)1.80796878
112Colon cancer (HP:0003003)1.80736647
113Abnormality of the intervertebral disk (HP:0005108)1.80389550
114Degeneration of the lateral corticospinal tracts (HP:0002314)1.80104052
115Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.80104052
116Aqueductal stenosis (HP:0002410)1.79643397
117Labial hypoplasia (HP:0000066)1.79017165
118Abnormality of chromosome segregation (HP:0002916)1.77355190
119Aplasia/Hypoplasia of the pubic bone (HP:0009104)1.75402494
120Preaxial hand polydactyly (HP:0001177)1.75355011
121Flat cornea (HP:0007720)1.75101114
122Pointed chin (HP:0000307)1.74637425
123Bifid tongue (HP:0010297)1.74300053
124Esotropia (HP:0000565)1.74202044
125Urinary bladder sphincter dysfunction (HP:0002839)1.73738546
126Broad-based gait (HP:0002136)1.73466225
127Progressive cerebellar ataxia (HP:0002073)1.73285925
128Gait imbalance (HP:0002141)1.72765159
129Abnormal pancreas size (HP:0012094)1.72699904
130Poor coordination (HP:0002370)1.72424804
131Double outlet right ventricle (HP:0001719)1.72414060
132Congenital malformation of the right heart (HP:0011723)1.72414060
133Genetic anticipation (HP:0003743)1.72411450
134Type II lissencephaly (HP:0007260)1.70925859
135Short philtrum (HP:0000322)1.70576065
136Decreased central vision (HP:0007663)1.70559454
137Oligodactyly (HP:0012165)1.69666754
138Diastasis recti (HP:0001540)1.69302661
139Oligodactyly (hands) (HP:0001180)1.69150310
140Hemiparesis (HP:0001269)1.68559141
141Trigonocephaly (HP:0000243)1.68395410
142Midline defect of the nose (HP:0004122)1.68211304
143Hemivertebrae (HP:0002937)1.68136519
144Abnormality of the septum pellucidum (HP:0007375)1.67757621
145Focal motor seizures (HP:0011153)1.67743381
146Open mouth (HP:0000194)1.67720465
147Postaxial hand polydactyly (HP:0001162)1.67515226
148Sleep apnea (HP:0010535)1.67251504
149Dandy-Walker malformation (HP:0001305)1.67164018
150Autism (HP:0000717)1.66663171
151Hyperglycinemia (HP:0002154)1.66129204
152Morphological abnormality of the middle ear (HP:0008609)1.65863693
153Thyroid-stimulating hormone excess (HP:0002925)1.65301682
154Chorioretinal coloboma (HP:0000567)1.62589031
155Spastic tetraplegia (HP:0002510)1.62034614
156Abnormality of abdominal situs (HP:0011620)1.61267582

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MARK14.27460487
2TNIK2.92546224
3UHMK12.80871666
4CASK2.54303339
5EPHB22.45880133
6DYRK22.28264684
7KSR12.23121439
8NTRK32.07680202
9NTRK22.02287078
10SIK22.00337382
11MKNK21.97914780
12IRAK21.88526169
13INSRR1.81244234
14ICK1.79391552
15CDK191.76290074
16BRD41.71773884
17PAK61.70581041
18ERBB31.68882929
19BCR1.65866871
20EPHA41.65839477
21CDK121.64717672
22PNCK1.62137220
23MAPK131.61776923
24CAMK1D1.61019973
25SRPK11.59960094
26DYRK31.59040800
27WNK31.56529745
28MKNK11.53015655
29TRIM281.46257849
30ERBB21.42446708
31BMPR1B1.42379721
32PASK1.41251212
33HIPK21.39428786
34PRKD31.37318243
35MAP2K41.36737485
36MARK21.35629036
37PRPF4B1.30614634
38DYRK1A1.29656539
39DYRK1B1.16745246
40TYRO31.13470669
41PLK41.13204086
42PINK11.09275661
43IRAK11.08872665
44CLK11.07770292
45MAP3K41.02875579
46PAK31.01888095
47CDK51.01852344
48CAMK1G1.01414323
49SGK4940.97625908
50SGK2230.97625908
51MAP3K90.97422646
52MAP4K20.95582725
53MAP3K100.95312532
54CSNK1G20.94887804
55CSNK1A1L0.94355332
56FGFR20.92716630
57CDC42BPA0.91882613
58SGK20.89379712
59CDK180.88402287
60CSNK1G30.85406016
61NTRK10.84623637
62CDK150.84274052
63MINK10.82756542
64ADRBK20.81826727
65CDK30.81533496
66STK160.81018834
67SIK30.80353031
68CDK140.80045127
69CDK11A0.79787395
70MAPK150.78341405
71PDGFRA0.76016228
72CDC70.74273671
73CSNK1G10.70955851
74OXSR10.69124602
75PHKG10.68582201
76PHKG20.68582201
77YES10.67976554
78TAF10.66570951
79STK390.66342656
80MAP2K70.66229334
81ZAK0.65116557
82MAPK90.65070449
83DAPK20.62470639
84STK110.62001348
85RIPK10.59965927
86GSK3B0.57924563
87MAP2K20.56645548
88NEK20.55807690
89PRKCG0.55446292
90WEE10.55072728
91EPHA30.54776557
92MAP3K20.54234071
93FGFR10.53169990
94LATS10.52569427
95GRK10.52421711
96CAMK40.52172882
97CDK10.51891261
98PTK60.51833835
99WNK40.51295949
100PLK20.50979540
101CAMKK10.50956370
102BCKDK0.50454378
103CSNK1E0.49519262
104CDK20.48935760
105MAPK100.48470341
106CAMK2B0.48268980
107MAP3K60.48257355
108BRAF0.47674916
109PTK20.47501513
110ALK0.46654043
111MAPK140.46324566
112SGK30.45789992
113CAMK10.44879505
114ROCK20.44690860
115NEK60.44233540
116PRKCZ0.43613366
117ATR0.43389133
118RPS6KA40.43374261
119PLK10.43237212
120RPS6KA20.42883989
121PRKCH0.42734105
122CSNK1A10.42354592
123CHEK20.42346594
124PRKDC0.41064007
125AURKA0.41028733
126PRKCE0.40451617
127TLK10.40310804
128CSNK1D0.40125906
129AKT10.39738353
130PKN10.39519536
131SGK10.39424969
132PRKACA0.38907824
133VRK10.38757110

Predicted pathways (KEGG)

RankGene SetZ-score
1Maturity onset diabetes of the young_Homo sapiens_hsa049503.93596274
2Phototransduction_Homo sapiens_hsa047442.96259700
3Axon guidance_Homo sapiens_hsa043602.88542842
4Nicotine addiction_Homo sapiens_hsa050332.44349822
5Cardiac muscle contraction_Homo sapiens_hsa042602.32368680
6Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.20579928
7Insulin secretion_Homo sapiens_hsa049112.09634678
8Basal cell carcinoma_Homo sapiens_hsa052172.08394003
9Glutamatergic synapse_Homo sapiens_hsa047242.04559314
10Cocaine addiction_Homo sapiens_hsa050302.00894615
11Steroid biosynthesis_Homo sapiens_hsa001001.99440126
12Oxidative phosphorylation_Homo sapiens_hsa001901.94386672
13Parkinsons disease_Homo sapiens_hsa050121.89844630
14Notch signaling pathway_Homo sapiens_hsa043301.85916070
15Ribosome_Homo sapiens_hsa030101.84662435
16Circadian entrainment_Homo sapiens_hsa047131.80548564
17Hedgehog signaling pathway_Homo sapiens_hsa043401.79287772
18GABAergic synapse_Homo sapiens_hsa047271.75391054
19Dopaminergic synapse_Homo sapiens_hsa047281.73392858
20mRNA surveillance pathway_Homo sapiens_hsa030151.71891332
21Wnt signaling pathway_Homo sapiens_hsa043101.64523274
22Morphine addiction_Homo sapiens_hsa050321.63891065
23Synaptic vesicle cycle_Homo sapiens_hsa047211.63198720
24Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.60427747
25Olfactory transduction_Homo sapiens_hsa047401.59606498
26Amphetamine addiction_Homo sapiens_hsa050311.55446617
27Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.55059981
28Type II diabetes mellitus_Homo sapiens_hsa049301.52274009
29Huntingtons disease_Homo sapiens_hsa050161.49683558
30Cholinergic synapse_Homo sapiens_hsa047251.46328244
31Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.43869020
32Basal transcription factors_Homo sapiens_hsa030221.38147496
33Taste transduction_Homo sapiens_hsa047421.38004519
34Long-term potentiation_Homo sapiens_hsa047201.35663418
35ErbB signaling pathway_Homo sapiens_hsa040121.34095165
36Spliceosome_Homo sapiens_hsa030401.33754908
37Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.33457729
38Alzheimers disease_Homo sapiens_hsa050101.29740190
39Circadian rhythm_Homo sapiens_hsa047101.28129842
40Melanogenesis_Homo sapiens_hsa049161.27785226
41Hippo signaling pathway_Homo sapiens_hsa043901.23194917
42Lysine degradation_Homo sapiens_hsa003101.22169299
43Gap junction_Homo sapiens_hsa045401.22086731
44Alcoholism_Homo sapiens_hsa050341.18952194
45Butanoate metabolism_Homo sapiens_hsa006501.18399789
46Serotonergic synapse_Homo sapiens_hsa047261.16642964
47Endometrial cancer_Homo sapiens_hsa052131.15646437
48Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.15130934
49Long-term depression_Homo sapiens_hsa047301.11167265
50Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.09482399
51Colorectal cancer_Homo sapiens_hsa052101.07169237
52Renal cell carcinoma_Homo sapiens_hsa052111.07027599
53Vibrio cholerae infection_Homo sapiens_hsa051101.06464461
54Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.05176867
55Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.04010939
56Aldosterone synthesis and secretion_Homo sapiens_hsa049251.02849140
57Estrogen signaling pathway_Homo sapiens_hsa049150.99051483
58Fanconi anemia pathway_Homo sapiens_hsa034600.98618313
59Thyroid hormone signaling pathway_Homo sapiens_hsa049190.97994170
60Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.95489852
61cAMP signaling pathway_Homo sapiens_hsa040240.94247788
62Glioma_Homo sapiens_hsa052140.93289803
63Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.92423689
64Protein export_Homo sapiens_hsa030600.90761560
65Oxytocin signaling pathway_Homo sapiens_hsa049210.89862921
66Phosphatidylinositol signaling system_Homo sapiens_hsa040700.89240821
67Oocyte meiosis_Homo sapiens_hsa041140.88559802
68Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.88222511
69Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.87264490
70Propanoate metabolism_Homo sapiens_hsa006400.85748898
71MicroRNAs in cancer_Homo sapiens_hsa052060.82594691
72Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.81555430
73RNA polymerase_Homo sapiens_hsa030200.80652730
74Gastric acid secretion_Homo sapiens_hsa049710.80362247
75Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.78642066
76GnRH signaling pathway_Homo sapiens_hsa049120.76785804
77N-Glycan biosynthesis_Homo sapiens_hsa005100.76532442
78RNA degradation_Homo sapiens_hsa030180.76239764
79Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.74607436
80Carbohydrate digestion and absorption_Homo sapiens_hsa049730.73661184
81Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.73508475
82Neurotrophin signaling pathway_Homo sapiens_hsa047220.72900508
83Adherens junction_Homo sapiens_hsa045200.70344778
84Phospholipase D signaling pathway_Homo sapiens_hsa040720.70132509
85Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.70109672
86MAPK signaling pathway_Homo sapiens_hsa040100.70050615
87Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.69708645
88Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.69534219
89mTOR signaling pathway_Homo sapiens_hsa041500.68025287
90Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.67447540
91RNA transport_Homo sapiens_hsa030130.67287615
92Longevity regulating pathway - mammal_Homo sapiens_hsa042110.66457520
93Chronic myeloid leukemia_Homo sapiens_hsa052200.65866692
94Choline metabolism in cancer_Homo sapiens_hsa052310.65836537
95cGMP-PKG signaling pathway_Homo sapiens_hsa040220.64859671
96Dorso-ventral axis formation_Homo sapiens_hsa043200.64363673
97Ras signaling pathway_Homo sapiens_hsa040140.64281678
98Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.63877075
99Pancreatic secretion_Homo sapiens_hsa049720.62875120
100Selenocompound metabolism_Homo sapiens_hsa004500.62571305
101Salivary secretion_Homo sapiens_hsa049700.60633635
102Dilated cardiomyopathy_Homo sapiens_hsa054140.59673604
103Inositol phosphate metabolism_Homo sapiens_hsa005620.58776613
104Renin secretion_Homo sapiens_hsa049240.57974741
105Prolactin signaling pathway_Homo sapiens_hsa049170.57341058
106alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.56966556
107Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.56538617
108Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.56099115
109Calcium signaling pathway_Homo sapiens_hsa040200.55605129
110Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.55134577
111Linoleic acid metabolism_Homo sapiens_hsa005910.55031704
112Rap1 signaling pathway_Homo sapiens_hsa040150.54291150
113FoxO signaling pathway_Homo sapiens_hsa040680.53739535
114Cell cycle_Homo sapiens_hsa041100.53310800
115Non-small cell lung cancer_Homo sapiens_hsa052230.52823307
116Glucagon signaling pathway_Homo sapiens_hsa049220.52815160
117Ether lipid metabolism_Homo sapiens_hsa005650.52479048
118Sphingolipid metabolism_Homo sapiens_hsa006000.52472442
119Tight junction_Homo sapiens_hsa045300.52136606
120Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.51695394
121AMPK signaling pathway_Homo sapiens_hsa041520.50851045
122Type I diabetes mellitus_Homo sapiens_hsa049400.50471180
123VEGF signaling pathway_Homo sapiens_hsa043700.48279184
124Insulin signaling pathway_Homo sapiens_hsa049100.48027729
125Thyroid hormone synthesis_Homo sapiens_hsa049180.47825108
126Fatty acid biosynthesis_Homo sapiens_hsa000610.47211721
127Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.46190903
128Regulation of autophagy_Homo sapiens_hsa041400.44261466
129Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.43119308
130Collecting duct acid secretion_Homo sapiens_hsa049660.42736451
131Vitamin B6 metabolism_Homo sapiens_hsa007500.42492510
132Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.42231066
133Homologous recombination_Homo sapiens_hsa034400.40207123
134Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.38077588
135Melanoma_Homo sapiens_hsa052180.37064650
136Fatty acid metabolism_Homo sapiens_hsa012120.35637989
137Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.35086657
138Base excision repair_Homo sapiens_hsa034100.31074450

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