PHGR1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of vacuole organization (GO:0044088)8.97780171
2angiotensin maturation (GO:0002003)8.97526615
3negative regulation of organelle assembly (GO:1902116)8.53587507
4cytidine metabolic process (GO:0046087)8.36163134
5cytidine catabolic process (GO:0006216)8.36163134
6cytidine deamination (GO:0009972)8.36163134
7negative regulation of epidermal growth factor-activated receptor activity (GO:0007175)8.16041127
8sulfate transmembrane transport (GO:1902358)7.62322105
9bile acid and bile salt transport (GO:0015721)7.35004412
10regulation of systemic arterial blood pressure by renin-angiotensin (GO:0003081)7.32406347
11protein neddylation (GO:0045116)7.24337895
12negative regulation of T cell differentiation in thymus (GO:0033085)7.15735861
13negative regulation of keratinocyte proliferation (GO:0010839)6.98846329
14keratinocyte development (GO:0003334)6.96657390
15chondrocyte proliferation (GO:0035988)6.96166123
163-phosphoadenosine 5-phosphosulfate metabolic process (GO:0050427)6.80394815
17purine ribonucleoside bisphosphate metabolic process (GO:0034035)6.80394815
18intestinal absorption (GO:0050892)6.73641791
19regulation of vitamin metabolic process (GO:0030656)6.68314931
20NADH metabolic process (GO:0006734)6.55912769
21sulfate transport (GO:0008272)6.33526189
22pyrimidine ribonucleoside catabolic process (GO:0046133)6.08634157
23alkaloid metabolic process (GO:0009820)5.98713908
24positive regulation of T cell differentiation in thymus (GO:0033089)5.88192438
25epoxygenase P450 pathway (GO:0019373)5.56133902
26fat-soluble vitamin biosynthetic process (GO:0042362)5.53524412
27somite development (GO:0061053)5.28986751
28negative regulation of protein tyrosine kinase activity (GO:0061099)5.28831821
29endocrine process (GO:0050886)5.28007223
30regulation of systemic arterial blood pressure by hormone (GO:0001990)5.28007223
31regulation of systemic arterial blood pressure mediated by a chemical signal (GO:0003044)5.28007223
32regulation of cellular extravasation (GO:0002691)5.23331658
33purine nucleoside bisphosphate biosynthetic process (GO:0034033)5.15426705
34ribonucleoside bisphosphate biosynthetic process (GO:0034030)5.15426705
35nucleoside bisphosphate biosynthetic process (GO:0033866)5.15426705
36positive regulation of respiratory burst (GO:0060267)5.14770078
37sulfur amino acid catabolic process (GO:0000098)5.12554367
38negative regulation of alpha-beta T cell differentiation (GO:0046639)5.05458959
39receptor guanylyl cyclase signaling pathway (GO:0007168)5.01076939
40renal system process involved in regulation of blood volume (GO:0001977)4.97858065
41positive regulation of pseudopodium assembly (GO:0031274)4.91798972
42regulation of viral release from host cell (GO:1902186)4.88989814
43mitotic G2 DNA damage checkpoint (GO:0007095)4.88262899
44lipoprotein transport (GO:0042953)4.84635136
45negative regulation of receptor activity (GO:2000272)4.83722411
46regulation of cGMP biosynthetic process (GO:0030826)4.78606270
47fructose metabolic process (GO:0006000)4.77808570
48regulation of systemic arterial blood pressure (GO:0003073)4.77137715
49positive regulation of epidermal cell differentiation (GO:0045606)4.60931477
50antibacterial humoral response (GO:0019731)4.52478681
51glucuronate metabolic process (GO:0019585)4.50576951
52uronic acid metabolic process (GO:0006063)4.50576951
53hormone catabolic process (GO:0042447)4.50129767
54regulation of keratinocyte proliferation (GO:0010837)4.50113556
55diacylglycerol metabolic process (GO:0046339)4.44895922
56antimicrobial humoral response (GO:0019730)4.41818889
57maintenance of gastrointestinal epithelium (GO:0030277)4.41353369
58regulation of pseudopodium assembly (GO:0031272)4.41352929
59epithelial cell-cell adhesion (GO:0090136)4.40504576
60sulfur compound transport (GO:0072348)4.33811311
61establishment of skin barrier (GO:0061436)4.30228355
62mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.27297976
63drug metabolic process (GO:0017144)4.23283106
64regulation of bile acid biosynthetic process (GO:0070857)4.13308352
65glomerular filtration (GO:0003094)4.10994200
66negative regulation of response to nutrient levels (GO:0032108)4.01974203
67negative regulation of response to extracellular stimulus (GO:0032105)4.01974203
68neurotransmitter biosynthetic process (GO:0042136)3.96413124
69regulation of cGMP metabolic process (GO:0030823)3.96188902
70urea cycle (GO:0000050)3.95539732
71positive regulation of epidermis development (GO:0045684)3.94636117
72cGMP-mediated signaling (GO:0019934)3.93586095
73extracellular matrix assembly (GO:0085029)3.92876782
74regulation of water loss via skin (GO:0033561)3.91707739
75calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338)3.90271619
76bone resorption (GO:0045453)3.89204204
77adhesion of symbiont to host cell (GO:0044650)3.88809544
78virion attachment to host cell (GO:0019062)3.88809544
79peptide catabolic process (GO:0043171)3.83770168
80pyrimidine-containing compound transmembrane transport (GO:0072531)3.79454114
81ethanol oxidation (GO:0006069)3.77983515
82flavonoid metabolic process (GO:0009812)3.77041188
83regulation of respiratory burst (GO:0060263)3.76198511
84phosphatidylcholine biosynthetic process (GO:0006656)3.75773036
85positive regulation of glycoprotein biosynthetic process (GO:0010560)3.75771469
86renal filtration (GO:0097205)3.75026267
87urea metabolic process (GO:0019627)3.74301158
88very-low-density lipoprotein particle assembly (GO:0034379)3.72322491
89antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.63310405
90mitotic G2/M transition checkpoint (GO:0044818)3.63301063
91peptide hormone processing (GO:0016486)3.63062767
92ribonucleoside bisphosphate metabolic process (GO:0033875)3.59738416
93nucleoside bisphosphate metabolic process (GO:0033865)3.59738416
94purine nucleoside bisphosphate metabolic process (GO:0034032)3.59738416
95nucleotide salvage (GO:0043173)3.57071627
96phospholipase C-activating dopamine receptor signaling pathway (GO:0060158)3.57002368
97oligosaccharide biosynthetic process (GO:0009312)3.54359043
98glycosphingolipid catabolic process (GO:0046479)3.53792343
99positive regulation of protein export from nucleus (GO:0046827)3.53642493
100renal system process involved in regulation of systemic arterial blood pressure (GO:0003071)3.52680291
101transcytosis (GO:0045056)3.52227394
102response to hepatocyte growth factor (GO:0035728)3.51423321
103cellular response to hepatocyte growth factor stimulus (GO:0035729)3.51423321
104ATP synthesis coupled proton transport (GO:0015986)3.51420512
105energy coupled proton transport, down electrochemical gradient (GO:0015985)3.51420512
106glycolipid catabolic process (GO:0019377)3.51142387
107actin filament depolymerization (GO:0030042)3.51009743
108antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.50572066
109oxidative phosphorylation (GO:0006119)3.50269158
110digestion (GO:0007586)3.49962341
111positive regulation of glycoprotein metabolic process (GO:1903020)3.48997308
112nitrogen cycle metabolic process (GO:0071941)3.47053868
113digestive system process (GO:0022600)3.38368692
114antigen processing and presentation of endogenous antigen (GO:0019883)3.37365083
115positive regulation of Cdc42 GTPase activity (GO:0043089)3.36327028
116positive regulation of fatty acid beta-oxidation (GO:0032000)3.32520918
117regulation of T cell differentiation in thymus (GO:0033081)3.31048237
118adhesion of symbiont to host (GO:0044406)3.29211438
119regulation of cholesterol homeostasis (GO:2000188)3.28186018
120glucocorticoid biosynthetic process (GO:0006704)3.27800052
121smooth muscle tissue development (GO:0048745)3.27338680
122cellular response to exogenous dsRNA (GO:0071360)3.26938568
123regulation of triglyceride catabolic process (GO:0010896)3.26876710
124regulation of guanylate cyclase activity (GO:0031282)3.26594478
125plasma lipoprotein particle assembly (GO:0034377)3.24656962
126fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)3.22857126
127positive regulation of cGMP biosynthetic process (GO:0030828)3.22630537
128epithelial structure maintenance (GO:0010669)3.21053817
129negative regulation of alpha-beta T cell activation (GO:0046636)3.20161238
130negative regulation of epidermal cell differentiation (GO:0045605)3.19043438
131regulation of developmental pigmentation (GO:0048070)3.18895058
132positive regulation of lipid catabolic process (GO:0050996)3.17641933
133auditory receptor cell differentiation (GO:0042491)3.16322632
134positive regulation of chondrocyte differentiation (GO:0032332)3.15708294
135eosinophil chemotaxis (GO:0048245)3.13743541
136drug transmembrane transport (GO:0006855)3.13697785
137positive regulation of hair cycle (GO:0042635)3.13036644
138positive regulation of hair follicle development (GO:0051798)3.13036644
139cellular response to nitric oxide (GO:0071732)3.11911489
140positive regulation of guanylate cyclase activity (GO:0031284)3.11056880
141nucleoside salvage (GO:0043174)3.09951161
142vitamin transport (GO:0051180)3.09233842
143GDP-mannose metabolic process (GO:0019673)3.08826312
144negative regulation of autophagy (GO:0010507)3.08032467
145pyrimidine nucleoside salvage (GO:0043097)3.07906277
146pyrimidine-containing compound salvage (GO:0008655)3.07906277
147O-glycan processing (GO:0016266)3.05610551
148negative regulation of defense response to virus (GO:0050687)3.05197397
149response to nitric oxide (GO:0071731)3.04147190
150protein-lipid complex assembly (GO:0065005)3.02440461
151arginine metabolic process (GO:0006525)3.01174166
152respiratory electron transport chain (GO:0022904)3.00911121
153drug catabolic process (GO:0042737)3.00191047
154vitamin A metabolic process (GO:0006776)2.98188777
155cGMP biosynthetic process (GO:0006182)2.97782165
156drug transport (GO:0015893)2.94017587
157sexual reproduction (GO:0019953)2.93106938
158electron transport chain (GO:0022900)2.92550308
159glycerol metabolic process (GO:0006071)2.91215874
160glutamine family amino acid biosynthetic process (GO:0009084)2.90770540
161ethanol metabolic process (GO:0006067)2.90480861
162establishment or maintenance of epithelial cell apical/basal polarity (GO:0045197)2.89959868
163desmosome organization (GO:0002934)2.89198787
164neurotransmitter metabolic process (GO:0042133)2.87105666
165heterochromatin organization (GO:0070828)2.84190703
166regulation of epidermal growth factor-activated receptor activity (GO:0007176)2.82385139
167embryonic camera-type eye morphogenesis (GO:0048596)2.80419863
168cellular ketone body metabolic process (GO:0046950)2.78874669
169vitamin transmembrane transport (GO:0035461)2.78427488
170bundle of His cell to Purkinje myocyte communication (GO:0086069)2.76238914
171release of cytochrome c from mitochondria (GO:0001836)2.75606709
172sulfation (GO:0051923)2.73588682
173cellular response to cAMP (GO:0071320)2.73290547
174regulation of cholesterol metabolic process (GO:0090181)2.73044212
175embryonic digestive tract morphogenesis (GO:0048557)2.72796232
176cellular glucuronidation (GO:0052695)2.72002807
177intestinal epithelial cell development (GO:0060576)2.69969798
178phospholipid homeostasis (GO:0055091)2.69946981
179nucleoside diphosphate biosynthetic process (GO:0009133)2.69719263
180mitochondrial electron transport, NADH to ubiquinone (GO:0006120)2.69451281
181mitochondrion localization (GO:0051646)2.63311223
182negative regulation of chemokine production (GO:0032682)2.60989997
183regulation of autophagic vacuole assembly (GO:2000785)11.0280002
184negative regulation of macroautophagy (GO:0016242)10.7604241

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TP63_17297297_ChIP-ChIP_HaCaT_Human8.31619860
2VDR_22108803_ChIP-Seq_LS180_Human3.25797634
3CDX2_20551321_ChIP-Seq_CACO-2_Human3.18388867
4CDX2_19796622_ChIP-Seq_MESCs_Mouse3.03988729
5SRY_22984422_ChIP-ChIP_TESTIS_Rat2.89334453
6ESR1_17901129_ChIP-ChIP_LIVER_Mouse2.88002552
7STAT6_21828071_ChIP-Seq_BEAS2B_Human2.86049785
8IRF8_22096565_ChIP-ChIP_GC-B_Human2.77275507
9IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.61130047
10SOX2_20726797_ChIP-Seq_SW620_Human2.45034471
11SOX2_27498859_Chip-Seq_STOMACH_Mouse2.38546618
12BMI1_19503595_ChIP-Seq_MEFsC_Mouse2.34454363
13GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.21926602
14RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human2.19038714
15SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.18504555
16IKZF1_21737484_ChIP-ChIP_HCT116_Human2.17987633
17PPARA_22158963_ChIP-Seq_LIVER_Mouse2.12040932
18PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.96607474
19FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.94309565
20TRIM28_21343339_ChIP-Seq_HEK293_Human1.93706842
21HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.83079006
22NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.78485523
23RXR_22158963_ChIP-Seq_LIVER_Mouse1.74987604
24NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.73517813
25ESR1_20079471_ChIP-ChIP_T-47D_Human1.70426091
26MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.65469081
27FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.60696868
28TCF4_18268006_ChIP-ChIP_LS174T_Human1.60372983
29POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.58889039
30RXR_22108803_ChIP-Seq_LS180_Human1.57905640
31PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.57722343
32ESR1_21235772_ChIP-Seq_MCF-7_Human1.56973823
33STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.51873105
34SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.51294694
35ESR2_21235772_ChIP-Seq_MCF-7_Human1.50845993
36CLOCK_20551151_ChIP-Seq_293T_Human1.50248375
37GATA4_25053715_ChIP-Seq_YYC3_Human1.50224817
38SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.49803498
39EGR1_19032775_ChIP-ChIP_M12_Human1.48912555
40EGR1_23403033_ChIP-Seq_LIVER_Mouse1.43292648
41RACK7_27058665_Chip-Seq_MCF-7_Human1.43040147
42PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.42579094
43ESR1_15608294_ChIP-ChIP_MCF-7_Human1.41097492
44GATA6_25053715_ChIP-Seq_YYC3_Human1.40186814
45GATA3_20176728_ChIP-ChIP_TSCs_Mouse1.38702257
46TET1_21451524_ChIP-Seq_MESCs_Mouse1.37135100
47ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.35511224
48LXR_22158963_ChIP-Seq_LIVER_Mouse1.33676853
49ERG_21242973_ChIP-ChIP_JURKAT_Human1.30952871
50KLF5_25053715_ChIP-Seq_YYC3_Human1.27362402
51CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.27244859
52BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.26258400
53GATA1_22025678_ChIP-Seq_K562_Human1.25474474
54TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.23872835
55GATA1_26923725_Chip-Seq_HPCs_Mouse1.23848386
56SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.22923906
57TCF7L2_21901280_ChIP-Seq_H4IIE_Rat1.22325481
58TAF2_19829295_ChIP-Seq_ESCs_Human1.22055570
59SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.21956713
60BCL6_27268052_Chip-Seq_Bcells_Human1.21905230
61CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.20386695
62TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.19864648
63P63_26484246_Chip-Seq_KERATINOCYTES_Human1.19560027
64JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse1.19096279
65PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.18588634
66FOXO3_23340844_ChIP-Seq_DLD1_Human1.17108796
67NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.17056560
68PPAR_26484153_Chip-Seq_NCI-H1993_Human1.16828619
69OCT4_18692474_ChIP-Seq_MEFs_Mouse1.16007633
70CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.15778210
71SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.14703854
72HNF4A_19822575_ChIP-Seq_HepG2_Human1.14272830
73ZNF263_19887448_ChIP-Seq_K562_Human1.14034047
74IRF8_21731497_ChIP-ChIP_J774_Mouse1.12929346
75KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.11772080
76KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.10444792
77CSB_26484114_Chip-Seq_FIBROBLAST_Human1.09694739
78NANOG_20526341_ChIP-Seq_ESCs_Human1.09479583
79SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.09356185
80LXR_22292898_ChIP-Seq_THP-1_Human1.09174380
81UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.07617339
82RUNX1_27514584_Chip-Seq_MCF-7_Human1.07002291
83RARG_19884340_ChIP-ChIP_MEFs_Mouse1.06848760
84GATA2_19941826_ChIP-Seq_K562_Human1.06446267
85SA1_27219007_Chip-Seq_Bcells_Human1.06323803
86SMC1_22415368_ChIP-Seq_MEFs_Mouse1.06252477
87GATA1_19941826_ChIP-Seq_K562_Human1.05209516
88SUZ12_27294783_Chip-Seq_ESCs_Mouse1.04466704
89CDX2_22108803_ChIP-Seq_LS180_Human1.02203602
90FOXA1_25552417_ChIP-Seq_VCAP_Human1.02175347
91* FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.01858319
92CTCF_27219007_Chip-Seq_Bcells_Human1.01110522
93VDR_24763502_ChIP-Seq_THP-1_Human1.00522823
94CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.00339976
95SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.00173256
96MTF2_20144788_ChIP-Seq_MESCs_Mouse0.99118020
97SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.98872824
98VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.98724560
99STAT1_20625510_ChIP-Seq_HELA_Human0.98354583
100BCOR_27268052_Chip-Seq_Bcells_Human0.97493707
101RAD21_21589869_ChIP-Seq_MESCs_Mouse0.97318356
102DNAJC2_21179169_ChIP-ChIP_NT2_Human0.96761351
103DROSHA_22980978_ChIP-Seq_HELA_Human0.96489527
104* TP63_22573176_ChIP-Seq_HFKS_Human0.96326219
105TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.95580535
106GATA1_22383799_ChIP-Seq_G1ME_Mouse0.95466472
107CEBPB_22108803_ChIP-Seq_LS180_Human0.94529647
108EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.94380796
109GATA2_22383799_ChIP-Seq_G1ME_Mouse0.94132242
110SUZ12_18692474_ChIP-Seq_MEFs_Mouse0.93600119
111SALL4_18804426_ChIP-ChIP_XEN_Mouse0.93417450
112E2F1_20622854_ChIP-Seq_HELA_Human0.93362307
113CREB1_26743006_Chip-Seq_LNCaP_Human0.92818960
114RNF2_18974828_ChIP-Seq_MESCs_Mouse0.92126598
115EZH2_18974828_ChIP-Seq_MESCs_Mouse0.92126598
116STAT3_20064451_ChIP-Seq_CD4+T_Mouse0.91919892
117NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.90643683
118JARID2_20075857_ChIP-Seq_MESCs_Mouse0.90607502
119BP1_19119308_ChIP-ChIP_Hs578T_Human0.90004558
120SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.89834832
121AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.89083403
122EZH2_27294783_Chip-Seq_ESCs_Mouse0.89039390
123FOXA2_19822575_ChIP-Seq_HepG2_Human0.88420223
124ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.88369237
125VDR_21846776_ChIP-Seq_THP-1_Human0.86916952
126JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.86657919
127TCF3_18692474_ChIP-Seq_MEFs_Mouse0.85600917
128FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.85479679
129ELK3_25401928_ChIP-Seq_HUVEC_Human0.84895271
130ETS1_21867929_ChIP-Seq_TH2_Mouse0.84462548
131RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.84450543
132NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse0.83883060
133GATA3_24758297_ChIP-Seq_MCF-7_Human0.83713032
134SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse0.83511464
135* CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.83265133
136EED_16625203_ChIP-ChIP_MESCs_Mouse0.83211310
137MYC_19915707_ChIP-ChIP_AK7_Human0.83059029
138KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.82718991
139ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.81598347
140THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.81381306

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003283_abnormal_digestive_organ9.93172467
2MP0010234_abnormal_vibrissa_follicle9.22754488
3MP0003315_abnormal_perineum_morphology4.93174976
4MP0009379_abnormal_foot_pigmentation4.01395401
5MP0002822_catalepsy3.94764394
6MP0002234_abnormal_pharynx_morphology3.93826183
7MP0000462_abnormal_digestive_system3.70947966
8MP0003183_abnormal_peptide_metabolism3.47493531
9MP0009053_abnormal_anal_canal3.46927081
10MP0001666_abnormal_nutrient_absorption3.05367122
11MP0004147_increased_porphyrin_level2.94752331
12MP0009840_abnormal_foam_cell2.74621355
13MP0003878_abnormal_ear_physiology2.69622066
14MP0005377_hearing/vestibular/ear_phenot2.69622066
15MP0005085_abnormal_gallbladder_physiolo2.20259576
16MP0003866_abnormal_defecation2.17851277
17MP0005409_darkened_coat_color2.14638296
18MP0005360_urolithiasis2.11970716
19MP0004019_abnormal_vitamin_homeostasis2.06790698
20MP0008875_abnormal_xenobiotic_pharmacok1.97681494
21MP0003566_abnormal_cell_adhesion1.94850006
22MP0005381_digestive/alimentary_phenotyp1.86273728
23MP0000678_abnormal_parathyroid_gland1.65746620
24MP0000477_abnormal_intestine_morphology1.65518090
25MP0005167_abnormal_blood-brain_barrier1.57253119
26MP0003868_abnormal_feces_composition1.53304572
27MP0005332_abnormal_amino_acid1.51275419
28MP0001663_abnormal_digestive_system1.49164631
29MP0010678_abnormal_skin_adnexa1.49153869
30MP0003252_abnormal_bile_duct1.47303630
31MP0005451_abnormal_body_composition1.46200553
32MP0001188_hyperpigmentation1.43141864
33MP0002796_impaired_skin_barrier1.39869939
34MP0003385_abnormal_body_wall1.38575752
35MP0005670_abnormal_white_adipose1.38525668
36MP0002876_abnormal_thyroid_physiology1.34132162
37MP0001873_stomach_inflammation1.33377645
38MP0002138_abnormal_hepatobiliary_system1.31359818
39MP0004782_abnormal_surfactant_physiolog1.31007432
40MP0001765_abnormal_ion_homeostasis1.29525932
41MP0002139_abnormal_hepatobiliary_system1.24826294
42MP0002098_abnormal_vibrissa_morphology1.23596125
43MP0010155_abnormal_intestine_physiology1.23298505
44MP0005365_abnormal_bile_salt1.20932667
45MP0000613_abnormal_salivary_gland1.17312324
46MP0001501_abnormal_sleep_pattern1.16991002
47MP0003724_increased_susceptibility_to1.16709009
48MP0004947_skin_inflammation1.16659955
49MP0001764_abnormal_homeostasis1.15427197
50MP0000490_abnormal_crypts_of1.13686944
51MP0003705_abnormal_hypodermis_morpholog1.13217017
52MP0001756_abnormal_urination1.12210683
53MP0004264_abnormal_extraembryonic_tissu1.09854593
54MP0001664_abnormal_digestion1.07787733
55MP0009643_abnormal_urine_homeostasis1.07481062
56MP0003045_fibrosis1.07052992
57MP0002282_abnormal_trachea_morphology1.06881573
58MP0000762_abnormal_tongue_morphology1.04545143
59MP0005636_abnormal_mineral_homeostasis1.03731899
60MP0000465_gastrointestinal_hemorrhage1.03192436
61MP0000230_abnormal_systemic_arterial1.00499142
62MP0009785_altered_susceptibility_to1.00286451
63MP0003937_abnormal_limbs/digits/tail_de0.97745637
64MP0001845_abnormal_inflammatory_respons0.95977130
65MP0002166_altered_tumor_susceptibility0.95763103
66MP0003806_abnormal_nucleotide_metabolis0.95469172
67MP0005666_abnormal_adipose_tissue0.93801860
68MP0000538_abnormal_urinary_bladder0.93570860
69MP0004185_abnormal_adipocyte_glucose0.93327132
70MP0000609_abnormal_liver_physiology0.91436008
71MP0004043_abnormal_pH_regulation0.90942632
72MP0002971_abnormal_brown_adipose0.88765207
73MP0003191_abnormal_cellular_cholesterol0.86281241
74MP0002932_abnormal_joint_morphology0.86157179
75MP0005025_abnormal_response_to0.84466347
76MP0003436_decreased_susceptibility_to0.83270579
77MP0004270_analgesia0.80532241
78MP0005058_abnormal_lysosome_morphology0.80386223
79MP0001835_abnormal_antigen_presentation0.78938504
80MP0000163_abnormal_cartilage_morphology0.78802278
81MP0005319_abnormal_enzyme/_coenzyme0.78176853
82MP0006082_CNS_inflammation0.75724227
83MP0005084_abnormal_gallbladder_morpholo0.75215929
84MP0010329_abnormal_lipoprotein_level0.74917341
85MP0005535_abnormal_body_temperature0.74241482
86MP0009115_abnormal_fat_cell0.73998439
87MP0005387_immune_system_phenotype0.73939368
88MP0001790_abnormal_immune_system0.73939368
89MP0004272_abnormal_basement_membrane0.72168264
90MP0005310_abnormal_salivary_gland0.68507615
91MP0002115_abnormal_skeleton_extremities0.68346454
92MP0009780_abnormal_chondrocyte_physiolo0.68282489
93MP0002006_tumorigenesis0.67037736
94MP0008469_abnormal_protein_level0.65396485
95MP0002118_abnormal_lipid_homeostasis0.64683191
96MP0009333_abnormal_splenocyte_physiolog0.64602175
97MP0004134_abnormal_chest_morphology0.63052939
98MP0003718_maternal_effect0.62648872
99MP0009642_abnormal_blood_homeostasis0.62366276
100MP0005165_increased_susceptibility_to0.62197332
101MP0002896_abnormal_bone_mineralization0.62100162
102MP0002009_preneoplasia0.62031329
103MP0002751_abnormal_autonomic_nervous0.60716864
104MP0005508_abnormal_skeleton_morphology0.60552637
105MP0000249_abnormal_blood_vessel0.59957451
106MP0002132_abnormal_respiratory_system0.59946847
107MP0003879_abnormal_hair_cell0.59534246
108MP0002233_abnormal_nose_morphology0.59257387
109MP0003329_amyloid_beta_deposits0.59193900
110MP0004858_abnormal_nervous_system0.58933012
111MP0000377_abnormal_hair_follicle0.56478494
112MP0000566_synostosis0.55702017
113MP0001533_abnormal_skeleton_physiology0.55610734
114MP0008569_lethality_at_weaning0.54651222
115MP0001800_abnormal_humoral_immune0.54358084
116MP0000537_abnormal_urethra_morphology0.52786991
117MP0001849_ear_inflammation0.52461364
118MP0000604_amyloidosis0.52259428
119MP0000470_abnormal_stomach_morphology0.52101603
120MP0010352_gastrointestinal_tract_polyps0.51941832
121MP0009250_abnormal_appendicular_skeleto0.50345750
122MP0005584_abnormal_enzyme/coenzyme_acti0.50110597
123MP0003453_abnormal_keratinocyte_physiol0.49901658
124MP0005501_abnormal_skin_physiology0.49901225
125MP0001216_abnormal_epidermal_layer0.48139517
126MP0002136_abnormal_kidney_physiology0.47979215
127MP0009672_abnormal_birth_weight0.46767683
128MP0008872_abnormal_physiological_respon0.44585647
129MP0003755_abnormal_palate_morphology0.43657676
130MP0005166_decreased_susceptibility_to0.43312235
131MP0000049_abnormal_middle_ear0.41369567
132MP0001340_abnormal_eyelid_morphology0.40443601
133MP0000367_abnormal_coat/_hair0.38537872
134MP0003300_gastrointestinal_ulcer0.37933036
135MP0003941_abnormal_skin_development0.37409789
136MP0008004_abnormal_stomach_pH0.34733971
137MP0002113_abnormal_skeleton_development0.33501355
138MP0003638_abnormal_response/metabolism_0.32989042
139MP0003795_abnormal_bone_structure0.31632454
140MP0000467_abnormal_esophagus_morphology0.31100899
141MP0002148_abnormal_hypersensitivity_rea0.29771765
142MP0003303_peritoneal_inflammation0.29135986
143MP0005448_abnormal_energy_balance0.28678074
144MP0001485_abnormal_pinna_reflex0.28406881
145MP0002111_abnormal_tail_morphology0.27392998

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of glutamine family amino acid metabolism (HP:0010902)8.57368410
2Posterior subcapsular cataract (HP:0007787)7.43649864
3Flat acetabular roof (HP:0003180)6.74480523
4Neonatal short-limb short stature (HP:0008921)6.49195795
5Malnutrition (HP:0004395)6.44953481
6Symphalangism affecting the phalanges of the hand (HP:0009773)6.26273789
7Abnormality of the distal phalanx of the thumb (HP:0009617)6.15888982
8Cupped ribs (HP:0000887)6.01497848
9Flat capital femoral epiphysis (HP:0003370)6.01068720
10Hydroxyprolinuria (HP:0003080)5.85717459
11Abnormality of proline metabolism (HP:0010907)5.85717459
12Breech presentation (HP:0001623)5.78908746
13Metabolic alkalosis (HP:0200114)5.55362680
14Decreased circulating renin level (HP:0003351)5.43599225
15Abnormality of the 1st metacarpal (HP:0010009)5.10162372
16Irregular epiphyses (HP:0010582)5.09414062
17Ileus (HP:0002595)4.82169290
18Chronic diarrhea (HP:0002028)4.81152988
19Abnormality of renin-angiotensin system (HP:0000847)4.71389778
20Aplasia/Hypoplasia involving the femoral head and neck (HP:0009108)4.71094470
21Abnormality of the vitamin B12 metabolism (HP:0004341)4.59281331
22Abnormality of carpal bone ossification (HP:0006257)4.59060893
23Abnormality of the proximal phalanges of the hand (HP:0009834)4.57862003
24Flattened epiphyses (HP:0003071)4.55648997
25Spinal cord compression (HP:0002176)4.42532422
26Abnormality of vitamin B metabolism (HP:0004340)4.27744046
27Subcapsular cataract (HP:0000523)4.25863608
28Alkalosis (HP:0001948)4.23944404
29Large earlobe (HP:0009748)4.17443270
30Systemic lupus erythematosus (HP:0002725)4.13685976
31Short middle phalanx of finger (HP:0005819)4.08271424
32Vertebral clefting (HP:0008428)4.06841074
33Abnormal cartilage morphology (HP:0002763)3.87090086
34Abnormality of the 2nd finger (HP:0004100)3.85674715
35Confusion (HP:0001289)3.80540618
36Widely patent fontanelles and sutures (HP:0004492)3.78535091
37Abnormality of the phalanges of the hallux (HP:0010057)3.77420154
38Fat malabsorption (HP:0002630)3.76992251
39Abnormality of the middle phalanges of the toes (HP:0010183)3.76734737
40Aplasia/Hypoplasia of the vertebrae (HP:0008515)3.75117419
41Vertebral hypoplasia (HP:0008417)3.75117419
42Aplasia/hypoplasia of the femur (HP:0005613)3.67061042
43Short phalanx of the thumb (HP:0009660)3.62220157
44Coronal craniosynostosis (HP:0004440)3.60226700
45Absent phalangeal crease (HP:0006109)3.53026305
46Abnormal hand bone ossification (HP:0010660)3.52514103
47Abnormal vertebral ossification (HP:0100569)3.51525233
48Abnormal ossification of hand bones (HP:0005921)3.51019313
49Hypoplastic ilia (HP:0000946)3.49702519
50Tracheal stenosis (HP:0002777)3.46347643
51Abnormality of vitamin metabolism (HP:0100508)3.44259056
52Abnormality of monocarboxylic acid metabolism (HP:0010996)3.44033267
53Short tibia (HP:0005736)3.42796307
54Breast hypoplasia (HP:0003187)3.42422533
55Abnormality of the epiphysis of the femoral head (HP:0010574)3.42173069
56Abnormal tarsal ossification (HP:0008369)3.41912575
57Hip contracture (HP:0003273)3.41382138
58Hypobetalipoproteinemia (HP:0003563)3.34647556
59Congenital sensorineural hearing impairment (HP:0008527)3.28433133
60Aplasia/Hypoplasia of the phalanges of the toes (HP:0010173)3.26099653
61Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.23690239
62Abnormality of femoral epiphyses (HP:0006499)3.17422996
63Abnormality involving the epiphyses of the lower limbs (HP:0006500)3.17422996
64Thin bony cortex (HP:0002753)3.11478395
65Abnormality of the femoral head (HP:0003368)3.10230882
66Abdominal distention (HP:0003270)3.09893866
67Nausea (HP:0002018)3.08961257
68Hemorrhage of the eye (HP:0011885)3.08617631
69Abnormality of chloride homeostasis (HP:0011422)2.99427987
70Short hallux (HP:0010109)2.99130747
71Proximal placement of thumb (HP:0009623)2.98518208
72Aplasia/Hypoplasia of the tibia (HP:0005772)2.98083882
73Hyperglycinuria (HP:0003108)2.96307697
74Acanthocytosis (HP:0001927)2.96208029
75Right ventricular cardiomyopathy (HP:0011663)2.94646154
76Abnormal finger flexion creases (HP:0006143)2.93008151
77Aplasia/Hypoplasia of the middle phalanges of the hand (HP:0009843)2.92811381
78Villous atrophy (HP:0011473)2.90583516
79Abnormality of small intestinal villus morphology (HP:0011472)2.90583516
80Relative macrocephaly (HP:0004482)2.90422940
81Lumbar hyperlordosis (HP:0002938)2.90369561
82Hyperparathyroidism (HP:0000843)2.90136504
83Visceral angiomatosis (HP:0100761)2.89639529
84Hyperaldosteronism (HP:0000859)2.89433864
85Shawl scrotum (HP:0000049)2.89388069
86Wide cranial sutures (HP:0010537)2.89151911
87Proximal tubulopathy (HP:0000114)2.88916158
88Ridged nail (HP:0001807)2.88701264
89Down-sloping shoulders (HP:0200021)2.88145093
90Fragile nails (HP:0001808)2.87965853
91Eczematoid dermatitis (HP:0000976)2.85821172
92Aplasia/Hypoplasia of the phalanges of the thumb (HP:0009658)2.84744577
93Flared iliac wings (HP:0002869)2.83298359
94Hip dysplasia (HP:0001385)2.81767930
95Glycosuria (HP:0003076)2.81480922
96Abnormality of urine glucose concentration (HP:0011016)2.81480922
97High anterior hairline (HP:0009890)2.81385432
98Increased hepatocellular lipid droplets (HP:0006565)2.73477621
99Aplasia/Hypoplasia involving the pelvis (HP:0009103)2.71951068
100Aplasia/Hypoplasia of the hallux (HP:0008362)2.71816354
101Ovoid vertebral bodies (HP:0003300)2.71587916
102Cone-rod dystrophy (HP:0000548)2.68767989
103Woolly hair (HP:0002224)2.68135643
104Deviation of the thumb (HP:0009603)2.68082672
105Hemangiomatosis (HP:0007461)2.63942857
106Abnormality of glycine metabolism (HP:0010895)2.60687388
107Abnormality of serine family amino acid metabolism (HP:0010894)2.60687388
108Nephrolithiasis (HP:0000787)2.60310156
109Pigmentary retinal degeneration (HP:0001146)2.60172380
110Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)2.59076166
111Xanthomatosis (HP:0000991)2.57893662
112Hypokalemia (HP:0002900)2.56658409
113Lipid accumulation in hepatocytes (HP:0006561)2.55180280
114Hyperammonemia (HP:0001987)2.53460513
115Increased purine levels (HP:0004368)2.52029425
116Hyperuricemia (HP:0002149)2.52029425
117Broad palm (HP:0001169)2.48775120
118Hypotension (HP:0002615)2.47929510
119Hoarse voice (HP:0001609)2.47258018
120Pili torti (HP:0003777)2.46735032
121Abnormality of the middle phalanges of the hand (HP:0009833)2.45379120
122Hypophosphatemia (HP:0002148)2.43920970
123Abnormal foot bone ossification (HP:0010675)2.41933242
124Limited hip movement (HP:0008800)2.36775667
125Abnormality of dicarboxylic acid metabolism (HP:0010995)2.36445012
126Dicarboxylic aciduria (HP:0003215)2.36445012
127Polar cataract (HP:0010696)2.36244096
128Flat face (HP:0012368)2.35217993
129Midline defect of the nose (HP:0004122)2.31475513
130Coxa vara (HP:0002812)2.31430308
131Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.31364025
132Megaloblastic anemia (HP:0001889)2.31077329
133Potter facies (HP:0002009)2.31015728
134Facial shape deformation (HP:0011334)2.31015728
135Renal tubular acidosis (HP:0001947)2.29574178
136Short humerus (HP:0005792)2.27033982
137Focal segmental glomerulosclerosis (HP:0000097)2.26492457
138Glomerulonephritis (HP:0000099)2.25203240
139Abnormality of potassium homeostasis (HP:0011042)2.24377098
140Hyponatremia (HP:0002902)2.23644515
141Abnormal delivery (HP:0001787)2.20607239
142Pterygium (HP:0001059)2.19990477
143Steatorrhea (HP:0002570)2.19771641
144Hyperphosphatemia (HP:0002905)2.18983234
145Renal Fanconi syndrome (HP:0001994)2.18908356
146Intrahepatic cholestasis (HP:0001406)2.17546272
147Abnormality of complement system (HP:0005339)2.14852323
148Increased intramyocellular lipid droplets (HP:0012240)2.14821415
149Short femoral neck (HP:0100864)2.14519470
150Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)2.13932604
151Conjugated hyperbilirubinemia (HP:0002908)2.13886668
152Cerebral palsy (HP:0100021)2.13358169
153Thickened nuchal skin fold (HP:0000474)2.12917127
154Growth hormone excess (HP:0000845)2.11178949
155Enlarged epiphyses (HP:0010580)2.09660874
156Abnormality of purine metabolism (HP:0004352)2.08722292
157Stillbirth (HP:0003826)2.08287407
158Hyperactive renin-angiotensin system (HP:0000841)2.06873995
159Sandal gap (HP:0001852)2.06640191
160Exertional dyspnea (HP:0002875)2.03581124
161Delayed epiphyseal ossification (HP:0002663)2.02982106
162Protuberant abdomen (HP:0001538)2.02268613
163Abnormal hair laboratory examination (HP:0003328)2.02183206
164Petechiae (HP:0000967)2.01841382
165Short thorax (HP:0010306)2.00160030
166Short ribs (HP:0000773)1.99744970
167Abnormal biliary tract morphology (HP:0012440)1.99575577
168Aplasia/hypoplasia of the humerus (HP:0006507)1.99340252
169Pancreatitis (HP:0001733)1.99093838
170Nephritis (HP:0000123)1.98825711
171Abnormality of nucleobase metabolism (HP:0010932)1.98391690
172Metabolic acidosis (HP:0001942)1.98011144
173Limited elbow extension (HP:0001377)1.97894274
174Complement deficiency (HP:0004431)1.97821342
175Increased muscle lipid content (HP:0009058)1.97315339
176Hypoplastic iliac wings (HP:0002866)1.97245907
177Biliary tract neoplasm (HP:0100574)1.96022454
178Dehydration (HP:0001944)1.95905179
179Gastrointestinal dysmotility (HP:0002579)1.94934192
180Abnormality of the costochondral junction (HP:0000919)1.93330985
181Abnormality of magnesium homeostasis (HP:0004921)1.91462131
182Abnormal urine phosphate concentration (HP:0012599)1.89885576
183Syncope (HP:0001279)1.88070302
184Segmental peripheral demyelination/remyelination (HP:0003481)1.85559046
185Hyperphosphaturia (HP:0003109)1.84657606
186Multiple lipomas (HP:0001012)1.83006936
187Gingivitis (HP:0000230)1.82244460
188Symptomatic seizures (HP:0011145)1.81262937
189Abnormality of aspartate family amino acid metabolism (HP:0010899)1.78575696
190Adrenal overactivity (HP:0002717)1.76938537
191Abnormality of pyrimidine metabolism (HP:0004353)1.75852194

Predicted kinase interactions (KEA)

RankGene SetZ-score
1ACVR1B7.08974928
2EPHB25.31836465
3EPHA24.03607659
4MAP3K102.70125943
5PIK3CA2.25393916
6RIPK12.10729911
7TAOK314.7286352
8TAOK11.82520672
9FGFR41.76432726
10MST1R1.70985632
11KSR21.69153118
12ARAF1.59079231
13GRK61.55333856
14MAP2K21.52610824
15TYK21.47795964
16MAP4K11.39774376
17STK241.36332539
18MAP3K91.33282035
19EPHA31.30809997
20PRPF4B1.30364859
21EPHB11.26677687
22MAP3K21.20670473
23TBK11.07511784
24ICK1.02144304
25MAP3K141.02023300
26LMTK20.97498052
27MAP3K130.96749941
28TNIK0.91312702
29PRKG20.88828714
30RIPK40.85037609
31MAP3K110.83055758
32MYLK0.82719138
33FGFR30.81901722
34ILK0.80908205
35FRK0.80682022
36PTK60.76164013
37PTK20.73803130
38NME10.69501736
39MAP2K10.68711595
40MAP3K120.67911257
41TRIB30.64292736
42NLK0.61563178
43MST40.61405539
44SMG10.60997407
45DYRK1B0.59839406
46FER0.59368231
47PDPK10.55038180
48PTK2B0.53236138
49CAMK2D0.50782685
50CDK190.50568610
51IKBKE0.47438034
52ZAP700.45564363
53ITK0.45186719
54PDK10.41309221
55MOS0.41253326
56PRKCZ0.40562423
57IRAK10.40114758
58JAK20.39551458
59BRAF0.38996604
60STK110.38961939
61MAP3K80.38904040
62BMX0.38136032
63MATK0.38010405
64FYN0.37463040
65PDGFRA0.37137654
66MAP3K10.37120505
67MET0.36945678
68PRKD20.36773132
69YES10.36540130
70AKT30.36487428
71JAK10.34816122
72ERBB20.34504772
73TESK10.31965716
74PRKCQ0.31608476
75CAMK2B0.30957079
76MAPKAPK20.30750931
77LYN0.29682439
78RPS6KA20.29558479
79AURKB0.29462303
80DYRK20.28755747
81MAP3K30.28604574
82PKN10.28395799
83SRC0.28369154
84PRKCD0.27820685
85MAPK110.27492012
86CSF1R0.27136517
87CAMK2G0.26059820
88DMPK0.25957465
89PIM20.25499279
90PAK10.24737857
91CSK0.24360492
92PIM10.23723273
93MAPKAPK30.22460482
94LRRK20.21928485
95PIK3CG0.21805686
96MELK0.21798886
97PRKCA0.21770999
98CDK60.21549427
99TTK0.21375143
100RPS6KB20.21074356
101IRAK40.21012632
102JAK30.20015273
103SYK0.19930277
104DAPK30.19439053
105DDR20.19287888
106PRKCI0.18723646
107PDK20.18634401
108CSNK1A10.18567527
109RAF10.18520702
110BMPR20.16243220
111KIT0.15622961
112ABL20.15411918
113FGFR10.14429847
114ZAK0.13185650
115TTN0.12095342
116TESK20.11616704
117SGK4940.11207703
118SGK2230.11207703
119CAMK2A0.09910442
120CDC42BPA0.09719914
121PAK40.09559341
122PRKD10.08060850
123TEC0.07878839
124BTK0.06696542
125OXSR10.05963181
126IGF1R0.05575053
127PRKAA20.05511666
128PRKCB0.05363014
129WNK40.05314790
130PRKACG0.04808424
131ERN10.03834045
132CDK150.03815521
133MAP3K70.03660850
134MAP2K60.03643784
135EPHA40.02444395
136STK390.02420874
137CDK180.01618726
138CLK10.01478243
139PLK10.01194355
140RET0.01110769
141RPS6KA10.00815681
142KSR10.00343288
143FGR0.00244701
144ADRBK1-0.0038500

Predicted pathways (KEGG)

RankGene SetZ-score
1Sulfur metabolism_Homo sapiens_hsa009207.16982210
2Cyanoamino acid metabolism_Homo sapiens_hsa004605.03951871
3Mineral absorption_Homo sapiens_hsa049783.49127172
4Vitamin digestion and absorption_Homo sapiens_hsa049773.37456599
5Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005332.94253997
6Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049602.89575538
7Oxidative phosphorylation_Homo sapiens_hsa001902.71239955
8Bile secretion_Homo sapiens_hsa049762.53859198
9Butirosin and neomycin biosynthesis_Homo sapiens_hsa005242.36931126
10Arginine biosynthesis_Homo sapiens_hsa002202.27670650
11Fat digestion and absorption_Homo sapiens_hsa049752.18557391
12Parkinsons disease_Homo sapiens_hsa050122.14881828
13Alzheimers disease_Homo sapiens_hsa050101.90767737
14Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.81248765
15Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.80218201
16Steroid biosynthesis_Homo sapiens_hsa001001.79244466
17Retinol metabolism_Homo sapiens_hsa008301.75235684
18Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.71029025
19Cardiac muscle contraction_Homo sapiens_hsa042601.67698301
20Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.66150978
21Steroid hormone biosynthesis_Homo sapiens_hsa001401.53088358
22Sulfur relay system_Homo sapiens_hsa041221.50776407
23Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.49099986
24Maturity onset diabetes of the young_Homo sapiens_hsa049501.47768148
25Butanoate metabolism_Homo sapiens_hsa006501.39391103
26PPAR signaling pathway_Homo sapiens_hsa033201.38551423
27Asthma_Homo sapiens_hsa053101.37660310
28Arginine and proline metabolism_Homo sapiens_hsa003301.34672487
29Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.33038947
30Galactose metabolism_Homo sapiens_hsa000521.31016692
312-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.26928037
32Salivary secretion_Homo sapiens_hsa049701.19922525
33Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.19012349
34Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.15990830
35Fructose and mannose metabolism_Homo sapiens_hsa000511.14736194
36Huntingtons disease_Homo sapiens_hsa050161.14730193
37Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.13581133
38Chemical carcinogenesis_Homo sapiens_hsa052041.13158108
39Drug metabolism - other enzymes_Homo sapiens_hsa009831.06223067
40Carbohydrate digestion and absorption_Homo sapiens_hsa049731.04698135
41Linoleic acid metabolism_Homo sapiens_hsa005911.04152648
42Pentose phosphate pathway_Homo sapiens_hsa000301.03771791
43Allograft rejection_Homo sapiens_hsa053301.03580326
44Pentose and glucuronate interconversions_Homo sapiens_hsa000401.03527208
45alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.01788247
46Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.01646306
47Hepatitis C_Homo sapiens_hsa051601.01040920
48Histidine metabolism_Homo sapiens_hsa003401.00848694
49Autoimmune thyroid disease_Homo sapiens_hsa053200.96750357
50Leukocyte transendothelial migration_Homo sapiens_hsa046700.93660342
51Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.92479894
52Graft-versus-host disease_Homo sapiens_hsa053320.91955808
53Pancreatic secretion_Homo sapiens_hsa049720.86179703
54Other glycan degradation_Homo sapiens_hsa005110.83436485
55Tight junction_Homo sapiens_hsa045300.79881402
56Staphylococcus aureus infection_Homo sapiens_hsa051500.79760489
57Chronic myeloid leukemia_Homo sapiens_hsa052200.79491774
58Glycerophospholipid metabolism_Homo sapiens_hsa005640.78596008
59Renin-angiotensin system_Homo sapiens_hsa046140.78502146
60Choline metabolism in cancer_Homo sapiens_hsa052310.78200338
61Starch and sucrose metabolism_Homo sapiens_hsa005000.77442377
62Type II diabetes mellitus_Homo sapiens_hsa049300.74411172
63Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.73294818
64Type I diabetes mellitus_Homo sapiens_hsa049400.71235731
65TNF signaling pathway_Homo sapiens_hsa046680.70149716
66Fatty acid degradation_Homo sapiens_hsa000710.69328646
67Propanoate metabolism_Homo sapiens_hsa006400.67464829
68Glycerolipid metabolism_Homo sapiens_hsa005610.67381584
69Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.65620057
70Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.62925464
71Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.61887406
72Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.61339385
73ErbB signaling pathway_Homo sapiens_hsa040120.58469582
74Glutathione metabolism_Homo sapiens_hsa004800.57077667
75Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.57042302
76Fatty acid metabolism_Homo sapiens_hsa012120.56122506
77Pertussis_Homo sapiens_hsa051330.54959088
78Tryptophan metabolism_Homo sapiens_hsa003800.54838856
79Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.54747820
80Endometrial cancer_Homo sapiens_hsa052130.54589498
81Sphingolipid metabolism_Homo sapiens_hsa006000.52963758
82Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.51927810
83Antigen processing and presentation_Homo sapiens_hsa046120.49891609
84Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.49789558
85Central carbon metabolism in cancer_Homo sapiens_hsa052300.48512624
86Renin secretion_Homo sapiens_hsa049240.47058297
87Axon guidance_Homo sapiens_hsa043600.46934945
88Thyroid hormone synthesis_Homo sapiens_hsa049180.45709739
89Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.45047853
90Leishmaniasis_Homo sapiens_hsa051400.42025104
91Pyruvate metabolism_Homo sapiens_hsa006200.41480945
92Carbon metabolism_Homo sapiens_hsa012000.40955489
93Peroxisome_Homo sapiens_hsa041460.40575144
94T cell receptor signaling pathway_Homo sapiens_hsa046600.40048325
95Salmonella infection_Homo sapiens_hsa051320.39688958
96Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.38740425
97Tyrosine metabolism_Homo sapiens_hsa003500.38596239
98RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.37733791
99Hedgehog signaling pathway_Homo sapiens_hsa043400.37659705
100Ovarian steroidogenesis_Homo sapiens_hsa049130.37115664
101Estrogen signaling pathway_Homo sapiens_hsa049150.36711437
102Nitrogen metabolism_Homo sapiens_hsa009100.36689547
103Arachidonic acid metabolism_Homo sapiens_hsa005900.36466886
104Protein digestion and absorption_Homo sapiens_hsa049740.36201198
105Insulin secretion_Homo sapiens_hsa049110.34437357
106Gap junction_Homo sapiens_hsa045400.33703810
107Primary bile acid biosynthesis_Homo sapiens_hsa001200.31876580
108VEGF signaling pathway_Homo sapiens_hsa043700.31045181
109Gastric acid secretion_Homo sapiens_hsa049710.30808672
110Metabolic pathways_Homo sapiens_hsa011000.29900856
111Insulin resistance_Homo sapiens_hsa049310.29781609
112Cocaine addiction_Homo sapiens_hsa050300.29637831
113Viral myocarditis_Homo sapiens_hsa054160.28991143
114Folate biosynthesis_Homo sapiens_hsa007900.27133688
115Toll-like receptor signaling pathway_Homo sapiens_hsa046200.26173144
116Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.26162875
117Phenylalanine metabolism_Homo sapiens_hsa003600.26126746
118Pancreatic cancer_Homo sapiens_hsa052120.25735115
119African trypanosomiasis_Homo sapiens_hsa051430.25694530
120Adipocytokine signaling pathway_Homo sapiens_hsa049200.24864284
121Intestinal immune network for IgA production_Homo sapiens_hsa046720.24321103
122Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.23503678
123Cholinergic synapse_Homo sapiens_hsa047250.21840347
124Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.21625470
125ABC transporters_Homo sapiens_hsa020100.21615004
126Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.20761780
127Amoebiasis_Homo sapiens_hsa051460.20303868
128Ether lipid metabolism_Homo sapiens_hsa005650.19158089
129Apoptosis_Homo sapiens_hsa042100.17633932
130Biosynthesis of amino acids_Homo sapiens_hsa012300.17579338
131Thyroid cancer_Homo sapiens_hsa052160.17376695
132Caffeine metabolism_Homo sapiens_hsa002320.16344138
133Toxoplasmosis_Homo sapiens_hsa051450.15240751
134Fatty acid biosynthesis_Homo sapiens_hsa000610.14136317
135Hematopoietic cell lineage_Homo sapiens_hsa046400.11844465
136Influenza A_Homo sapiens_hsa051640.09638404
137Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.08924625
138GnRH signaling pathway_Homo sapiens_hsa049120.08721294
139Tuberculosis_Homo sapiens_hsa051520.07397899
140Chemokine signaling pathway_Homo sapiens_hsa040620.05796976

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