

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | acrosome assembly (GO:0001675) | 6.47162049 |
| 2 | sulfate transmembrane transport (GO:1902358) | 6.31216743 |
| 3 | mRNA modification (GO:0016556) | 6.06340131 |
| 4 | regulation of low-density lipoprotein particle receptor biosynthetic process (GO:0045714) | 5.90914937 |
| 5 | sterol catabolic process (GO:0016127) | 5.69009868 |
| 6 | cholesterol catabolic process (GO:0006707) | 5.69009868 |
| 7 | melanocyte differentiation (GO:0030318) | 5.54930655 |
| 8 | regulation of cholesterol homeostasis (GO:2000188) | 5.52405654 |
| 9 | sulfate transport (GO:0008272) | 5.31046361 |
| 10 | DNA replication-dependent nucleosome assembly (GO:0006335) | 5.19020175 |
| 11 | DNA replication-dependent nucleosome organization (GO:0034723) | 5.19020175 |
| 12 | COPII vesicle coating (GO:0048208) | 5.14134935 |
| 13 | virion assembly (GO:0019068) | 4.98421457 |
| 14 | pigment cell differentiation (GO:0050931) | 4.90105417 |
| 15 | negative regulation of cell aging (GO:0090344) | 4.89056907 |
| 16 | entrainment of circadian clock by photoperiod (GO:0043153) | 4.86249877 |
| 17 | base-excision repair (GO:0006284) | 4.76978041 |
| 18 | TOR signaling (GO:0031929) | 4.74613624 |
| 19 | entrainment of circadian clock (GO:0009649) | 4.71892401 |
| 20 | negative regulation of keratinocyte proliferation (GO:0010839) | 4.64956822 |
| 21 | mitotic sister chromatid cohesion (GO:0007064) | 4.53489177 |
| 22 | negative regulation of hematopoietic progenitor cell differentiation (GO:1901533) | 4.46517062 |
| 23 | cerebral cortex radially oriented cell migration (GO:0021799) | 4.44592726 |
| 24 | viral protein processing (GO:0019082) | 4.39809831 |
| 25 | positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic proc | 4.35669126 |
| 26 | tRNA methylation (GO:0030488) | 4.31485109 |
| 27 | positive regulation of astrocyte differentiation (GO:0048711) | 4.24441270 |
| 28 | lipoprotein transport (GO:0042953) | 4.20757347 |
| 29 | embryonic digestive tract morphogenesis (GO:0048557) | 4.18864260 |
| 30 | mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003337) | 4.15053688 |
| 31 | base-excision repair, AP site formation (GO:0006285) | 4.12410145 |
| 32 | cytidine metabolic process (GO:0046087) | 4.12099702 |
| 33 | cytidine catabolic process (GO:0006216) | 4.12099702 |
| 34 | cytidine deamination (GO:0009972) | 4.12099702 |
| 35 | positive regulation of extracellular matrix organization (GO:1903055) | 4.08835338 |
| 36 | regulation of megakaryocyte differentiation (GO:0045652) | 4.05118884 |
| 37 | positive regulation of stem cell differentiation (GO:2000738) | 4.02345731 |
| 38 | mitochondrial calcium ion homeostasis (GO:0051560) | 4.00627044 |
| 39 | meiotic chromosome segregation (GO:0045132) | 4.00130293 |
| 40 | positive regulation of mitochondrial membrane permeability (GO:0035794) | 3.99280201 |
| 41 | mitochondrial DNA replication (GO:0006264) | 3.97567621 |
| 42 | regulation of synapse maturation (GO:0090128) | 3.85203346 |
| 43 | photoperiodism (GO:0009648) | 3.83599978 |
| 44 | mitochondrial genome maintenance (GO:0000002) | 3.81987695 |
| 45 | translesion synthesis (GO:0019985) | 3.78859215 |
| 46 | mesenchymal cell differentiation involved in renal system development (GO:2001012) | 3.77902651 |
| 47 | mesenchymal cell differentiation involved in kidney development (GO:0072161) | 3.77902651 |
| 48 | mucosal-associated lymphoid tissue development (GO:0048537) | 3.77726729 |
| 49 | Peyers patch development (GO:0048541) | 3.77726729 |
| 50 | DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 cla | 3.75421138 |
| 51 | positive regulation of neuroblast proliferation (GO:0002052) | 3.75352234 |
| 52 | GDP-mannose metabolic process (GO:0019673) | 3.74548648 |
| 53 | seminiferous tubule development (GO:0072520) | 3.70386155 |
| 54 | negative regulation of stress fiber assembly (GO:0051497) | 3.65332592 |
| 55 | neuroepithelial cell differentiation (GO:0060563) | 3.65148146 |
| 56 | regulation of metalloenzyme activity (GO:0048552) | 3.64287364 |
| 57 | establishment of protein localization to Golgi (GO:0072600) | 3.62685889 |
| 58 | regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083) | 3.60766636 |
| 59 | protein targeting to Golgi (GO:0000042) | 3.59126696 |
| 60 | regulation of gene silencing (GO:0060968) | 3.59049439 |
| 61 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 3.58377914 |
| 62 | response to gravity (GO:0009629) | 3.57971834 |
| 63 | regulation of ER to Golgi vesicle-mediated transport (GO:0060628) | 3.52777473 |
| 64 | regulation of calcineurin-NFAT signaling cascade (GO:0070884) | 3.49909959 |
| 65 | mammary gland epithelial cell proliferation (GO:0033598) | 3.48396601 |
| 66 | cell proliferation in forebrain (GO:0021846) | 3.43061460 |
| 67 | histone deubiquitination (GO:0016578) | 3.40032377 |
| 68 | mammary gland epithelial cell differentiation (GO:0060644) | 3.37042594 |
| 69 | mRNA splice site selection (GO:0006376) | 3.36117705 |
| 70 | positive regulation of erythrocyte differentiation (GO:0045648) | 3.34285967 |
| 71 | detection of light stimulus involved in visual perception (GO:0050908) | 3.33311368 |
| 72 | detection of light stimulus involved in sensory perception (GO:0050962) | 3.33311368 |
| 73 | DNA damage response, signal transduction resulting in transcription (GO:0042772) | 3.31010506 |
| 74 | retrograde transport, vesicle recycling within Golgi (GO:0000301) | 3.25003439 |
| 75 | positive regulation of histone deacetylation (GO:0031065) | 3.24640167 |
| 76 | positive regulation of DNA-dependent DNA replication (GO:2000105) | 3.23424088 |
| 77 | protein polyglutamylation (GO:0018095) | 3.21630060 |
| 78 | regulation of cell migration involved in sprouting angiogenesis (GO:0090049) | 3.20381457 |
| 79 | peptidyl-lysine dimethylation (GO:0018027) | 3.19473314 |
| 80 | regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process (GO:2 | 3.18012863 |
| 81 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 3.15866091 |
| 82 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 3.15866091 |
| 83 | regulation of receptor biosynthetic process (GO:0010869) | 3.15278088 |
| 84 | cellular response to ATP (GO:0071318) | 3.14584635 |
| 85 | regulation of hormone biosynthetic process (GO:0046885) | 3.12797360 |
| 86 | protein K6-linked ubiquitination (GO:0085020) | 3.11981041 |
| 87 | regulation of centriole replication (GO:0046599) | 3.10544502 |
| 88 | negative regulation of oligodendrocyte differentiation (GO:0048715) | 3.08449737 |
| 89 | negative regulation of gene silencing (GO:0060969) | 3.07092644 |
| 90 | response to stimulus involved in regulation of muscle adaptation (GO:0014874) | 3.06617129 |
| 91 | negative regulation of actin filament bundle assembly (GO:0032232) | 3.03260819 |
| 92 | RNA localization (GO:0006403) | 3.00776831 |
| 93 | positive regulation of protein homooligomerization (GO:0032464) | 2.99932925 |
| 94 | fibroblast migration (GO:0010761) | 2.99560645 |
| 95 | ER to Golgi vesicle-mediated transport (GO:0006888) | 2.97522685 |
| 96 | stem cell differentiation (GO:0048863) | 2.97382909 |
| 97 | mitochondrial outer membrane permeabilization involved in programmed cell death (GO:1902686) | 2.97335176 |
| 98 | positive regulation of mitochondrial membrane permeability involved in apoptotic process (GO:1902110 | 2.97335176 |
| 99 | myoblast migration (GO:0051451) | 2.93542889 |
| 100 | hematopoietic stem cell differentiation (GO:0060218) | 12.7938621 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 8.42614306 |
| 2 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 8.32341862 |
| 3 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 5.94034876 |
| 4 | E2F7_22180533_ChIP-Seq_HELA_Human | 4.89604311 |
| 5 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 4.38316444 |
| 6 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 3.90756060 |
| 7 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 3.88867841 |
| 8 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 3.88867841 |
| 9 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 3.88867841 |
| 10 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 3.50803000 |
| 11 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 3.41353203 |
| 12 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 3.38072006 |
| 13 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 3.20800675 |
| 14 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 2.60292892 |
| 15 | ELK4_26923725_Chip-Seq_MESODERM_Mouse | 2.33420721 |
| 16 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 2.04822949 |
| 17 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 2.04567812 |
| 18 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 2.02967836 |
| 19 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 1.89666268 |
| 20 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.87714408 |
| 21 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 1.77305366 |
| 22 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.77159843 |
| 23 | MYC_22102868_ChIP-Seq_BL_Human | 1.74356166 |
| 24 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.70567839 |
| 25 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 1.54581438 |
| 26 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.39401405 |
| 27 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.37985718 |
| 28 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.37340026 |
| 29 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.31693659 |
| 30 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 1.27117981 |
| 31 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.26190085 |
| 32 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.25743926 |
| 33 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.23235427 |
| 34 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.20814923 |
| 35 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 1.15046423 |
| 36 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.14231731 |
| 37 | RUNX1_27514584_Chip-Seq_MCF-7_Human | 1.09930201 |
| 38 | RARB_24833708_ChIP-Seq_LIVER_Mouse | 1.09662305 |
| 39 | ZIC3_20872845_ChIP-ChIP_MESCs_Mouse | 1.08549946 |
| 40 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.06940359 |
| 41 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 1.06534908 |
| 42 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.06347060 |
| 43 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.03994254 |
| 44 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.03401781 |
| 45 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.03304952 |
| 46 | BRD4_25478319_ChIP-Seq_HGPS_Human | 0.99731504 |
| 47 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 0.98638770 |
| 48 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 0.98145218 |
| 49 | ATF3_27146783_Chip-Seq_COLON_Human | 0.97559695 |
| 50 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 0.95720661 |
| 51 | FLI1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 0.95030261 |
| 52 | PKCTHETA_26484144_Chip-Seq_BREAST_Human | 0.93405236 |
| 53 | GATA3_24758297_ChIP-Seq_MCF-7_Human | 0.92808227 |
| 54 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 0.91200496 |
| 55 | DCP1A_22483619_ChIP-Seq_HELA_Human | 0.91074047 |
| 56 | TCF7_22412390_ChIP-Seq_EML_Mouse | 0.90825223 |
| 57 | NACC1_18358816_ChIP-ChIP_MESCs_Mouse | 0.90238426 |
| 58 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 0.89981862 |
| 59 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 0.89040795 |
| 60 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 0.89036619 |
| 61 | CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 0.88148245 |
| 62 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.86676278 |
| 63 | CIITA_25753668_ChIP-Seq_RAJI_Human | 0.84100362 |
| 64 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.83791209 |
| 65 | RACK7_27058665_Chip-Seq_MCF-7_Human | 0.82465116 |
| 66 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 0.82427833 |
| 67 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 0.82113090 |
| 68 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 0.81013808 |
| 69 | E2F1_20622854_ChIP-Seq_HELA_Human | 0.79492550 |
| 70 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.78304027 |
| 71 | RARA_24833708_ChIP-Seq_LIVER_Mouse | 0.76437901 |
| 72 | STAT3_19079543_ChIP-ChIP_MESCs_Mouse | 0.76381667 |
| 73 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 0.75734368 |
| 74 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 0.75490420 |
| 75 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 0.73399738 |
| 76 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.73168938 |
| 77 | RXRA_24833708_ChIP-Seq_LIVER_Mouse | 0.72106382 |
| 78 | SMC4_20622854_ChIP-Seq_HELA_Human | 0.71458017 |
| 79 | FOXP1_21924763_ChIP-Seq_HESCs_Human | 0.71329527 |
| 80 | PHF8_20622854_ChIP-Seq_HELA_Human | 0.70512866 |
| 81 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 0.69909986 |
| 82 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 0.69189541 |
| 83 | AHR_22903824_ChIP-Seq_MCF-7_Human | 0.69102184 |
| 84 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 0.68802294 |
| 85 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 0.68564572 |
| 86 | ZNF274_21170338_ChIP-Seq_K562_Hela | 0.65612351 |
| 87 | FUS_26573619_Chip-Seq_HEK293_Human | 0.64904240 |
| 88 | SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 0.64378806 |
| 89 | SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 0.64378806 |
| 90 | AR_21915096_ChIP-Seq_LNCaP-1F5_Human | 0.63702485 |
| 91 | KDM2B_26808549_Chip-Seq_DND41_Human | 0.62631920 |
| 92 | DROSHA_22980978_ChIP-Seq_HELA_Human | 0.62396858 |
| 93 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.60916554 |
| 94 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.60852520 |
| 95 | FOXA2_19822575_ChIP-Seq_HepG2_Human | 0.60232416 |
| 96 | SOX2_27498859_Chip-Seq_STOMACH_Mouse | 0.58174854 |
| 97 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 0.58099323 |
| 98 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 0.57666024 |
| 99 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 0.56991545 |
| 100 | GATA6_25053715_ChIP-Seq_YYC3_Human | 0.56768598 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0008004_abnormal_stomach_pH | 9.30496702 |
| 2 | MP0000003_abnormal_adipose_tissue | 6.58013296 |
| 3 | MP0005076_abnormal_cell_differentiation | 3.13091447 |
| 4 | MP0001502_abnormal_circadian_rhythm | 3.03860822 |
| 5 | MP0005375_adipose_tissue_phenotype | 2.77241626 |
| 6 | MP0004233_abnormal_muscle_weight | 2.51733779 |
| 7 | MP0002933_joint_inflammation | 2.43978967 |
| 8 | MP0008961_abnormal_basal_metabolism | 2.22575140 |
| 9 | MP0009278_abnormal_bone_marrow | 2.22100249 |
| 10 | MP0000371_diluted_coat_color | 2.09906164 |
| 11 | MP0009250_abnormal_appendicular_skeleto | 2.09347838 |
| 12 | MP0000013_abnormal_adipose_tissue | 10.2363955 |
| 13 | MP0001986_abnormal_taste_sensitivity | 1.83193661 |
| 14 | MP0008260_abnormal_autophagy | 1.82483306 |
| 15 | MP0010030_abnormal_orbit_morphology | 1.70036508 |
| 16 | MP0003077_abnormal_cell_cycle | 1.66129585 |
| 17 | MP0006054_spinal_hemorrhage | 1.61539562 |
| 18 | MP0001984_abnormal_olfaction | 1.51640858 |
| 19 | MP0010307_abnormal_tumor_latency | 1.49233831 |
| 20 | MP0002896_abnormal_bone_mineralization | 1.32366978 |
| 21 | MP0003221_abnormal_cardiomyocyte_apopto | 1.32146933 |
| 22 | MP0009115_abnormal_fat_cell | 1.30656482 |
| 23 | MP0002736_abnormal_nociception_after | 1.30495581 |
| 24 | MP0000470_abnormal_stomach_morphology | 1.26518445 |
| 25 | MP0003195_calcinosis | 1.26438050 |
| 26 | MP0004484_altered_response_of | 1.23464038 |
| 27 | MP0004808_abnormal_hematopoietic_stem | 1.19217693 |
| 28 | MP0010094_abnormal_chromosome_stability | 1.16165174 |
| 29 | MP0002075_abnormal_coat/hair_pigmentati | 1.15789123 |
| 30 | MP0000566_synostosis | 1.12619046 |
| 31 | MP0005551_abnormal_eye_electrophysiolog | 1.11924368 |
| 32 | MP0000627_abnormal_mammary_gland | 1.07852508 |
| 33 | MP0004145_abnormal_muscle_electrophysio | 1.05980673 |
| 34 | MP0005334_abnormal_fat_pad | 1.02514767 |
| 35 | MP0003959_abnormal_lean_body | 1.00175061 |
| 36 | MP0001186_pigmentation_phenotype | 0.97805079 |
| 37 | MP0000750_abnormal_muscle_regeneration | 0.96961458 |
| 38 | MP0000538_abnormal_urinary_bladder | 0.96565416 |
| 39 | MP0010368_abnormal_lymphatic_system | 0.94708004 |
| 40 | MP0001968_abnormal_touch/_nociception | 0.93124669 |
| 41 | MP0000767_abnormal_smooth_muscle | 0.91365949 |
| 42 | MP0003948_abnormal_gas_homeostasis | 0.90129485 |
| 43 | MP0003111_abnormal_nucleus_morphology | 0.85692617 |
| 44 | MP0003191_abnormal_cellular_cholesterol | 0.85513130 |
| 45 | MP0004087_abnormal_muscle_fiber | 0.82473788 |
| 46 | MP0002210_abnormal_sex_determination | 0.77678879 |
| 47 | MP0004742_abnormal_vestibular_system | 0.76393783 |
| 48 | MP0001672_abnormal_embryogenesis/_devel | 0.71167123 |
| 49 | MP0005380_embryogenesis_phenotype | 0.71167123 |
| 50 | MP0003984_embryonic_growth_retardation | 0.70363223 |
| 51 | MP0001666_abnormal_nutrient_absorption | 0.68690626 |
| 52 | MP0000749_muscle_degeneration | 0.67047875 |
| 53 | MP0002088_abnormal_embryonic_growth/wei | 0.66804623 |
| 54 | MP0005452_abnormal_adipose_tissue | 0.66710983 |
| 55 | MP0009931_abnormal_skin_appearance | 0.65244600 |
| 56 | MP0003943_abnormal_hepatobiliary_system | 0.62690188 |
| 57 | MP0001661_extended_life_span | 0.62242553 |
| 58 | MP0008058_abnormal_DNA_repair | 0.61410339 |
| 59 | MP0001485_abnormal_pinna_reflex | 0.60774219 |
| 60 | MP0004019_abnormal_vitamin_homeostasis | 0.60383215 |
| 61 | MP0004885_abnormal_endolymph | 0.58572555 |
| 62 | MP0003693_abnormal_embryo_hatching | 0.58270056 |
| 63 | MP0003786_premature_aging | 0.57695480 |
| 64 | MP0002019_abnormal_tumor_incidence | 0.55331946 |
| 65 | MP0008057_abnormal_DNA_replication | 0.54372622 |
| 66 | MP0004036_abnormal_muscle_relaxation | 0.54303705 |
| 67 | MP0002168_other_aberrant_phenotype | 0.53750234 |
| 68 | MP0005174_abnormal_tail_pigmentation | 0.53047152 |
| 69 | MP0002118_abnormal_lipid_homeostasis | 0.52740192 |
| 70 | MP0002970_abnormal_white_adipose | 0.52187789 |
| 71 | MP0004264_abnormal_extraembryonic_tissu | 0.51747257 |
| 72 | MP0000427_abnormal_hair_cycle | 0.49765338 |
| 73 | MP0003787_abnormal_imprinting | 0.49318766 |
| 74 | MP0000759_abnormal_skeletal_muscle | 0.48271487 |
| 75 | MP0001944_abnormal_pancreas_morphology | 0.48199385 |
| 76 | MP0001664_abnormal_digestion | 0.48140182 |
| 77 | MP0010329_abnormal_lipoprotein_level | 0.48021454 |
| 78 | MP0002282_abnormal_trachea_morphology | 0.47923160 |
| 79 | MP0002106_abnormal_muscle_physiology | 0.47611579 |
| 80 | MP0005646_abnormal_pituitary_gland | 0.47385195 |
| 81 | MP0003045_fibrosis | 0.46700422 |
| 82 | MP0002081_perinatal_lethality | 0.46374050 |
| 83 | MP0001145_abnormal_male_reproductive | 0.46245789 |
| 84 | MP0000747_muscle_weakness | 0.46210644 |
| 85 | MP0002114_abnormal_axial_skeleton | 0.45811097 |
| 86 | MP0008770_decreased_survivor_rate | 0.45803820 |
| 87 | MP0005409_darkened_coat_color | 0.45386176 |
| 88 | MP0008438_abnormal_cutaneous_collagen | 0.45374432 |
| 89 | MP0001943_abnormal_respiration | 0.45217654 |
| 90 | MP0001929_abnormal_gametogenesis | 0.44818988 |
| 91 | MP0002135_abnormal_kidney_morphology | 0.43975955 |
| 92 | MP0000762_abnormal_tongue_morphology | 0.43424566 |
| 93 | MP0002928_abnormal_bile_duct | 0.43264080 |
| 94 | MP0001879_abnormal_lymphatic_vessel | 0.42496642 |
| 95 | MP0010770_preweaning_lethality | 0.42234176 |
| 96 | MP0002082_postnatal_lethality | 0.42234176 |
| 97 | MP0004197_abnormal_fetal_growth/weight/ | 0.41888838 |
| 98 | MP0010768_mortality/aging | 0.41885801 |
| 99 | MP0003755_abnormal_palate_morphology | 0.41439501 |
| 100 | MP0002332_abnormal_exercise_endurance | 0.41104067 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Generalized hypopigmentation of hair (HP:0011358) | 5.78763395 |
| 2 | Hypoplasia of the fovea (HP:0007750) | 5.17165533 |
| 3 | Aplasia/Hypoplasia of the fovea (HP:0008060) | 5.17165533 |
| 4 | Anterior segment dysgenesis (HP:0007700) | 4.75480741 |
| 5 | Prominent supraorbital ridges (HP:0000336) | 4.70844386 |
| 6 | Renal cortical cysts (HP:0000803) | 4.46233785 |
| 7 | Abnormality of the renal cortex (HP:0011035) | 4.43691606 |
| 8 | Exercise-induced myalgia (HP:0003738) | 4.35041754 |
| 9 | Vertebral arch anomaly (HP:0008438) | 4.34347297 |
| 10 | Proximal amyotrophy (HP:0007126) | 4.32849345 |
| 11 | Villous atrophy (HP:0011473) | 4.30647646 |
| 12 | Abnormality of small intestinal villus morphology (HP:0011472) | 4.30647646 |
| 13 | Abnormality of the fovea (HP:0000493) | 4.20576947 |
| 14 | Thrombocytosis (HP:0001894) | 4.11060631 |
| 15 | Wormian bones (HP:0002645) | 4.05451771 |
| 16 | Curly hair (HP:0002212) | 3.87787482 |
| 17 | Cholecystitis (HP:0001082) | 3.84092593 |
| 18 | Abnormal gallbladder physiology (HP:0012438) | 3.84092593 |
| 19 | Rib fusion (HP:0000902) | 3.75786069 |
| 20 | Small epiphyses (HP:0010585) | 3.75178384 |
| 21 | Progressive external ophthalmoplegia (HP:0000590) | 3.59124228 |
| 22 | Delayed epiphyseal ossification (HP:0002663) | 3.53435930 |
| 23 | Abnormality of methionine metabolism (HP:0010901) | 3.50507891 |
| 24 | Flat capital femoral epiphysis (HP:0003370) | 3.37167542 |
| 25 | Generalized hypopigmentation (HP:0007513) | 3.32817410 |
| 26 | Abnormal hair laboratory examination (HP:0003328) | 3.32510769 |
| 27 | Ocular albinism (HP:0001107) | 3.28134895 |
| 28 | Abnormal albumin level (HP:0012116) | 3.26259976 |
| 29 | Hypoalbuminemia (HP:0003073) | 3.26259976 |
| 30 | Prominent forehead (HP:0011220) | 3.22498572 |
| 31 | Tracheomalacia (HP:0002779) | 3.16971927 |
| 32 | Aplasia/Hypoplasia of the macula (HP:0008059) | 3.12860978 |
| 33 | Abnormality of sulfur amino acid metabolism (HP:0004339) | 2.95782143 |
| 34 | Hypoplasia of the capital femoral epiphysis (HP:0003090) | 2.94902405 |
| 35 | Aortic regurgitation (HP:0001659) | 2.88372561 |
| 36 | Woolly hair (HP:0002224) | 2.85035165 |
| 37 | Aplasia/Hypoplasia affecting the retina (HP:0008061) | 2.82742886 |
| 38 | Abnormality of the labia majora (HP:0012881) | 2.79389341 |
| 39 | Hypoplastic labia majora (HP:0000059) | 2.77196287 |
| 40 | Iris hypopigmentation (HP:0007730) | 2.70867722 |
| 41 | Abnormality of the proximal phalanges of the hand (HP:0009834) | 2.66533434 |
| 42 | Overlapping toe (HP:0001845) | 2.63419091 |
| 43 | Increased mean platelet volume (HP:0011877) | 2.60932278 |
| 44 | Volvulus (HP:0002580) | 2.60848299 |
| 45 | Polyuria (HP:0000103) | 2.56720808 |
| 46 | Broad distal phalanx of finger (HP:0009836) | 2.56012673 |
| 47 | Aplasia/Hypoplasia involving the carpal bones (HP:0006502) | 2.55300194 |
| 48 | Metaphyseal irregularity (HP:0003025) | 2.53923540 |
| 49 | Proximal placement of thumb (HP:0009623) | 2.51841277 |
| 50 | Narrow mouth (HP:0000160) | 2.49702774 |
| 51 | Carpal bone hypoplasia (HP:0001498) | 2.48563316 |
| 52 | Broad nasal tip (HP:0000455) | 2.48256035 |
| 53 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.43376093 |
| 54 | Flattened epiphyses (HP:0003071) | 2.41959066 |
| 55 | Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003) | 2.40591156 |
| 56 | Absent epiphyses (HP:0010577) | 2.40591156 |
| 57 | Absent speech (HP:0001344) | 2.37140376 |
| 58 | Abnormal platelet volume (HP:0011876) | 2.32140022 |
| 59 | Rhabdomyolysis (HP:0003201) | 2.31069784 |
| 60 | Bifid uvula (HP:0000193) | 2.28609161 |
| 61 | Tetraplegia (HP:0002445) | 2.27933482 |
| 62 | Deviation of the thumb (HP:0009603) | 2.27870875 |
| 63 | Low anterior hairline (HP:0000294) | 2.22736991 |
| 64 | Capillary hemangiomas (HP:0005306) | 2.21735472 |
| 65 | Interstitial pulmonary disease (HP:0006530) | 2.17042854 |
| 66 | Aplasia/Hypoplasia affecting the fundus (HP:0008057) | 2.16096821 |
| 67 | Abnormal drinking behavior (HP:0030082) | 2.14915661 |
| 68 | Polydipsia (HP:0001959) | 2.14915661 |
| 69 | Dislocated radial head (HP:0003083) | 2.14787037 |
| 70 | Progressive muscle weakness (HP:0003323) | 2.14703490 |
| 71 | Heterotopia (HP:0002282) | 2.13998161 |
| 72 | Midface retrusion (HP:0011800) | 2.10112095 |
| 73 | Nausea (HP:0002018) | 2.09983864 |
| 74 | Chorioretinal coloboma (HP:0000567) | 2.09740583 |
| 75 | Brittle hair (HP:0002299) | 2.06903228 |
| 76 | Abnormality of chloride homeostasis (HP:0011422) | 2.06884599 |
| 77 | Facial hemangioma (HP:0000329) | 2.05860575 |
| 78 | Pseudobulbar signs (HP:0002200) | 2.05684350 |
| 79 | Myoglobinuria (HP:0002913) | 2.03604399 |
| 80 | Irregular epiphyses (HP:0010582) | 2.02819073 |
| 81 | Ependymoma (HP:0002888) | 2.01547978 |
| 82 | Abnormal urine output (HP:0012590) | 2.00550113 |
| 83 | Abnormality of the renal medulla (HP:0100957) | 2.00451884 |
| 84 | Easy fatigability (HP:0003388) | 1.99658139 |
| 85 | Glossoptosis (HP:0000162) | 1.99041966 |
| 86 | Facial asymmetry (HP:0000324) | 1.98942426 |
| 87 | Abnormality of the anterior chamber (HP:0000593) | 1.97639036 |
| 88 | Hyperaldosteronism (HP:0000859) | 1.96989609 |
| 89 | Conjugated hyperbilirubinemia (HP:0002908) | 1.96643850 |
| 90 | Patent foramen ovale (HP:0001655) | 1.95356791 |
| 91 | Stomach cancer (HP:0012126) | 1.94047410 |
| 92 | Abnormality of the radial head (HP:0003995) | 1.93640287 |
| 93 | Nasal speech (HP:0001611) | 1.88213510 |
| 94 | Nonimmune hydrops fetalis (HP:0001790) | 1.87818155 |
| 95 | Esotropia (HP:0000565) | 1.86067774 |
| 96 | Vacuolated lymphocytes (HP:0001922) | 1.85955011 |
| 97 | Intellectual disability, moderate (HP:0002342) | 1.85198199 |
| 98 | Scrotal hypoplasia (HP:0000046) | 1.84428735 |
| 99 | Congenital stationary night blindness (HP:0007642) | 1.84225073 |
| 100 | Low posterior hairline (HP:0002162) | 1.84134711 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TLK1 | 8.28219379 |
| 2 | ZAK | 6.94678335 |
| 3 | CASK | 6.77287512 |
| 4 | CDK12 | 4.18129603 |
| 5 | PHKG1 | 2.70959659 |
| 6 | PHKG2 | 2.70959659 |
| 7 | MST4 | 2.64089316 |
| 8 | BCKDK | 2.55587465 |
| 9 | TRIM28 | 2.20004429 |
| 10 | TSSK6 | 2.11709609 |
| 11 | WNK4 | 2.10051964 |
| 12 | FLT3 | 1.98052918 |
| 13 | VRK1 | 1.95159893 |
| 14 | KDR | 1.79592256 |
| 15 | CCNB1 | 1.59479441 |
| 16 | STK38L | 1.48775481 |
| 17 | PIM1 | 1.22784717 |
| 18 | STK24 | 1.18923311 |
| 19 | EPHA2 | 1.13980904 |
| 20 | MET | 1.13716266 |
| 21 | MELK | 1.10715684 |
| 22 | BMX | 1.07447283 |
| 23 | RPS6KA5 | 1.05864063 |
| 24 | WEE1 | 1.02154552 |
| 25 | AKT2 | 0.98673982 |
| 26 | ICK | 0.93290987 |
| 27 | OBSCN | 0.90982194 |
| 28 | DAPK2 | 0.90357306 |
| 29 | STK39 | 0.82920199 |
| 30 | CHEK2 | 0.79683862 |
| 31 | SIK3 | 0.77936772 |
| 32 | BMPR1B | 0.75396251 |
| 33 | MAP3K5 | 0.75365862 |
| 34 | CDK6 | 0.75185498 |
| 35 | JAK3 | 0.73279924 |
| 36 | NTRK1 | 0.72042649 |
| 37 | PKN1 | 0.70804826 |
| 38 | STK10 | 0.68459485 |
| 39 | PRKCI | 0.66954410 |
| 40 | PRKAA1 | 0.64951648 |
| 41 | PNCK | 0.64520045 |
| 42 | MAPK15 | 0.62051001 |
| 43 | CDK7 | 0.61295059 |
| 44 | STK4 | 0.59421196 |
| 45 | WNK1 | 0.57804674 |
| 46 | MAPK14 | 0.56926479 |
| 47 | EPHA3 | 0.56358499 |
| 48 | AURKB | 0.55519232 |
| 49 | PRKCQ | 0.53123517 |
| 50 | LATS2 | 0.45181480 |
| 51 | MKNK2 | 0.44662723 |
| 52 | CDK8 | 0.44152482 |
| 53 | CAMK1G | 0.43631533 |
| 54 | ROCK1 | 0.42544583 |
| 55 | PDK2 | 0.40027579 |
| 56 | CDK4 | 0.39647508 |
| 57 | MTOR | 0.38694953 |
| 58 | PBK | 0.38370284 |
| 59 | NEK6 | 0.37680786 |
| 60 | ERBB4 | 0.37351980 |
| 61 | TAOK3 | 0.36285164 |
| 62 | MAPK10 | 0.36090909 |
| 63 | PTK2 | 0.35933942 |
| 64 | MKNK1 | 0.35920163 |
| 65 | LRRK2 | 0.34117557 |
| 66 | MAPK9 | 0.33962460 |
| 67 | CDK2 | 0.32531550 |
| 68 | MST1R | 0.32133211 |
| 69 | MAP3K8 | 0.31860778 |
| 70 | JAK2 | 0.27680616 |
| 71 | GSK3B | 0.27003119 |
| 72 | MAP3K14 | 0.26798735 |
| 73 | DAPK3 | 0.25991960 |
| 74 | CDK1 | 0.25525418 |
| 75 | JAK1 | 0.24967033 |
| 76 | AURKA | 0.24594859 |
| 77 | MAP3K1 | 0.24323742 |
| 78 | PRKAA2 | 0.23371915 |
| 79 | PIK3CA | 0.19239304 |
| 80 | CDK9 | 0.18339969 |
| 81 | STK3 | 0.17435295 |
| 82 | TRPM7 | 0.17380217 |
| 83 | PDGFRA | 0.16557659 |
| 84 | CHUK | 0.15129316 |
| 85 | PDPK1 | 0.14922108 |
| 86 | PLK1 | 0.14157598 |
| 87 | CDC7 | 0.13260010 |
| 88 | MATK | 0.11650698 |
| 89 | CSNK1E | 0.11122788 |
| 90 | ZAP70 | 0.11004830 |
| 91 | TNK2 | 0.10616050 |
| 92 | CHEK1 | 0.10475751 |
| 93 | HIPK2 | 0.09859134 |
| 94 | ATR | 0.09341556 |
| 95 | MUSK | 0.09228761 |
| 96 | ATM | 0.08800013 |
| 97 | CSNK1A1L | 0.06809607 |
| 98 | MAP3K12 | 0.06214692 |
| 99 | LMTK2 | 0.05654324 |
| 100 | RPS6KB1 | 0.05390069 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Base excision repair_Homo sapiens_hsa03410 | 7.23808921 |
| 2 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 3.91731057 |
| 3 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 3.39209607 |
| 4 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 3.15086881 |
| 5 | Selenocompound metabolism_Homo sapiens_hsa00450 | 3.10328463 |
| 6 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.86095512 |
| 7 | Alcoholism_Homo sapiens_hsa05034 | 2.65776151 |
| 8 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 2.54511783 |
| 9 | Circadian rhythm_Homo sapiens_hsa04710 | 2.08164117 |
| 10 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.99418123 |
| 11 | DNA replication_Homo sapiens_hsa03030 | 1.77513560 |
| 12 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 1.70705507 |
| 13 | Lysine degradation_Homo sapiens_hsa00310 | 1.58808017 |
| 14 | RNA transport_Homo sapiens_hsa03013 | 1.58685130 |
| 15 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 1.51616188 |
| 16 | RNA degradation_Homo sapiens_hsa03018 | 1.40651625 |
| 17 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 1.40632500 |
| 18 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 1.40430820 |
| 19 | Thyroid cancer_Homo sapiens_hsa05216 | 1.35895390 |
| 20 | RNA polymerase_Homo sapiens_hsa03020 | 1.30953496 |
| 21 | Mismatch repair_Homo sapiens_hsa03430 | 1.29671631 |
| 22 | Mineral absorption_Homo sapiens_hsa04978 | 1.24754461 |
| 23 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 1.19820378 |
| 24 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 1.17607811 |
| 25 | Spliceosome_Homo sapiens_hsa03040 | 1.17539367 |
| 26 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 1.16769158 |
| 27 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.14846641 |
| 28 | Viral carcinogenesis_Homo sapiens_hsa05203 | 1.14572571 |
| 29 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.12944062 |
| 30 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 1.07588855 |
| 31 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.06015387 |
| 32 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 1.00992818 |
| 33 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.99992544 |
| 34 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.99288911 |
| 35 | Cell cycle_Homo sapiens_hsa04110 | 0.98721822 |
| 36 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.97840202 |
| 37 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.95129902 |
| 38 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.95093305 |
| 39 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.92444567 |
| 40 | Insulin resistance_Homo sapiens_hsa04931 | 0.88233120 |
| 41 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.86735768 |
| 42 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.84245071 |
| 43 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.83386042 |
| 44 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.80182044 |
| 45 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.79413548 |
| 46 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.77392408 |
| 47 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.75481874 |
| 48 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.74507120 |
| 49 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.71173708 |
| 50 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.70453336 |
| 51 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.68720127 |
| 52 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.68445929 |
| 53 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.64468315 |
| 54 | Galactose metabolism_Homo sapiens_hsa00052 | 0.61743138 |
| 55 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.58910625 |
| 56 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.56974620 |
| 57 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.56523797 |
| 58 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.54314532 |
| 59 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.53655513 |
| 60 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.52707957 |
| 61 | Phototransduction_Homo sapiens_hsa04744 | 0.52655671 |
| 62 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.52637016 |
| 63 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.51235015 |
| 64 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.49883300 |
| 65 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.49563336 |
| 66 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.48547659 |
| 67 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.46459100 |
| 68 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.45216015 |
| 69 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.44375172 |
| 70 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.43149066 |
| 71 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.42715350 |
| 72 | Purine metabolism_Homo sapiens_hsa00230 | 0.41824358 |
| 73 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.41822299 |
| 74 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.41389133 |
| 75 | Prostate cancer_Homo sapiens_hsa05215 | 0.40432742 |
| 76 | Homologous recombination_Homo sapiens_hsa03440 | 0.39799838 |
| 77 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.37419703 |
| 78 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.35265658 |
| 79 | Salivary secretion_Homo sapiens_hsa04970 | 0.35077303 |
| 80 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.34962459 |
| 81 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.34907067 |
| 82 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.34558736 |
| 83 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.34177589 |
| 84 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.34079062 |
| 85 | Sulfur relay system_Homo sapiens_hsa04122 | 0.33700948 |
| 86 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.33521839 |
| 87 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.31715551 |
| 88 | ABC transporters_Homo sapiens_hsa02010 | 0.31445368 |
| 89 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.29928623 |
| 90 | Melanogenesis_Homo sapiens_hsa04916 | 0.29422158 |
| 91 | Bile secretion_Homo sapiens_hsa04976 | 0.29013291 |
| 92 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.27208016 |
| 93 | Tight junction_Homo sapiens_hsa04530 | 0.26379122 |
| 94 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.25826801 |
| 95 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.25711812 |
| 96 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.25600371 |
| 97 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.25442975 |
| 98 | Insulin secretion_Homo sapiens_hsa04911 | 0.24849829 |
| 99 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.24434031 |
| 100 | Taste transduction_Homo sapiens_hsa04742 | 0.22414262 |

