PHLDB1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1central nervous system myelination (GO:0022010)5.16335581
2axon ensheathment in central nervous system (GO:0032291)5.16335581
3synaptic vesicle docking involved in exocytosis (GO:0016081)4.04717627
4plasma membrane repair (GO:0001778)3.82479386
5cytoskeletal anchoring at plasma membrane (GO:0007016)3.61552425
6axon ensheathment (GO:0008366)3.58009428
7ensheathment of neurons (GO:0007272)3.58009428
8myelination (GO:0042552)3.50182063
9negative regulation of protein localization to cell surface (GO:2000009)3.31045362
10peptidyl-tyrosine autophosphorylation (GO:0038083)3.22330497
11glycine transport (GO:0015816)3.21282444
12cardiac myofibril assembly (GO:0055003)3.18059320
13creatine metabolic process (GO:0006600)3.13407528
14negative regulation of potassium ion transmembrane transporter activity (GO:1901017)3.12560215
15myelin maintenance (GO:0043217)3.11275019
16myelination in peripheral nervous system (GO:0022011)3.09335807
17peripheral nervous system axon ensheathment (GO:0032292)3.09335807
18negative regulation of potassium ion transmembrane transport (GO:1901380)3.07181028
19regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)3.07047970
20synaptic vesicle maturation (GO:0016188)3.06890730
21locomotory exploration behavior (GO:0035641)3.04835324
22sarcomere organization (GO:0045214)2.98399410
23extracellular matrix assembly (GO:0085029)2.98334012
24stress fiber assembly (GO:0043149)2.91508919
25regulation of synapse structural plasticity (GO:0051823)2.88760181
26myofibril assembly (GO:0030239)2.88249802
27glutamate secretion (GO:0014047)2.81506257
28layer formation in cerebral cortex (GO:0021819)2.80826835
29cell migration involved in heart development (GO:0060973)2.78906413
30membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.78350397
31dermatan sulfate metabolic process (GO:0030205)2.78026199
32cell communication by electrical coupling involved in cardiac conduction (GO:0086064)2.77973810
33vascular endothelial growth factor signaling pathway (GO:0038084)2.77020221
34postsynaptic membrane organization (GO:0001941)2.76986832
35astrocyte development (GO:0014002)2.75290896
36endothelial cell morphogenesis (GO:0001886)2.75186870
37establishment of nucleus localization (GO:0040023)2.74073872
38dermatan sulfate biosynthetic process (GO:0030208)2.71953099
39cell communication by electrical coupling (GO:0010644)2.68031308
40neuronal ion channel clustering (GO:0045161)2.66578530
41protein heterotrimerization (GO:0070208)2.65132646
42protein localization to endosome (GO:0036010)2.63720603
43regulation of axon extension involved in axon guidance (GO:0048841)2.62042677
44dendritic spine morphogenesis (GO:0060997)2.61984780
45regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)2.61136514
46peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan (GO:0019800)2.60992690
47lymphangiogenesis (GO:0001946)2.59165431
48cellular potassium ion homeostasis (GO:0030007)2.58792217
49regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO2.57557141
50negative regulation of synaptic transmission, GABAergic (GO:0032229)2.57064319
51membrane tubulation (GO:0097320)2.56248650
52protein targeting to plasma membrane (GO:0072661)2.54761058
53actomyosin structure organization (GO:0031032)2.54045435
54positive regulation of calcium ion-dependent exocytosis (GO:0045956)2.53986371
55endothelial cell chemotaxis (GO:0035767)2.53820395
56dendrite morphogenesis (GO:0048813)2.53674330
57cellular response to epinephrine stimulus (GO:0071872)2.52091564
58neuron projection extension involved in neuron projection guidance (GO:1902284)2.50602898
59axon extension involved in axon guidance (GO:0048846)2.50602898
60sodium ion export (GO:0071436)2.46824058
61potassium ion import (GO:0010107)2.46524448
62cellular response to catecholamine stimulus (GO:0071870)2.46496265
63cellular response to monoamine stimulus (GO:0071868)2.46496265
64metanephric nephron epithelium development (GO:0072243)2.46270195
65vocalization behavior (GO:0071625)2.46230624
66neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976)2.45473782
67collagen fibril organization (GO:0030199)2.45232204
68regulation of vascular endothelial growth factor signaling pathway (GO:1900746)2.45106020
69chondrocyte proliferation (GO:0035988)2.44564332
70endodermal cell differentiation (GO:0035987)2.44266002
71cell communication involved in cardiac conduction (GO:0086065)2.44239589
72regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314)2.43967752
73activation of protein kinase A activity (GO:0034199)2.43733759
74positive regulation of excitatory postsynaptic membrane potential (GO:2000463)2.42060814
75regulation of membrane repolarization (GO:0060306)2.41712498
76regulation of dendritic spine morphogenesis (GO:0061001)2.41033211
77cellular response to vascular endothelial growth factor stimulus (GO:0035924)2.40747903
78neuromuscular junction development (GO:0007528)2.40198651
79L-amino acid import (GO:0043092)2.38392001
80positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)2.36813017
81glomerular filtration (GO:0003094)2.36031154
82regulation of synapse maturation (GO:0090128)2.35260176
83cell-substrate junction assembly (GO:0007044)2.34180812
84cortical actin cytoskeleton organization (GO:0030866)2.34046700
85barbed-end actin filament capping (GO:0051016)2.33641209
86nerve growth factor signaling pathway (GO:0038180)2.33623771
87regulation of actin filament-based movement (GO:1903115)2.32133655
88semaphorin-plexin signaling pathway (GO:0071526)2.32075342
89regulation of axon guidance (GO:1902667)2.31743240
90metanephric nephron tubule development (GO:0072234)2.31545449
91metanephric tubule development (GO:0072170)2.31545449
92synaptic vesicle exocytosis (GO:0016079)2.31543740
93cardiac muscle contraction (GO:0060048)2.31251934
94positive regulation of synapse maturation (GO:0090129)2.30923069
95negative regulation of cytosolic calcium ion concentration (GO:0051481)2.30918207
96neuromuscular process controlling balance (GO:0050885)2.30740739
97regulation of voltage-gated calcium channel activity (GO:1901385)2.28851211
98negative regulation of catenin import into nucleus (GO:0035414)2.27897045
99regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)2.27845187
100regulation of short-term neuronal synaptic plasticity (GO:0048172)2.27743840
101renal filtration (GO:0097205)2.27640289
102regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)2.26876227
103regulation of p38MAPK cascade (GO:1900744)2.26267452
104retina vasculature morphogenesis in camera-type eye (GO:0061299)2.25459631
105cerebellar Purkinje cell layer development (GO:0021680)2.24859313
106regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act2.23829300
107metanephric epithelium development (GO:0072207)2.23704938
108membrane assembly (GO:0071709)2.23298022
109insulin-like growth factor receptor signaling pathway (GO:0048009)2.23102202
110camera-type eye morphogenesis (GO:0048593)2.23081836
111amino acid import (GO:0043090)2.23035779
112regulation of calcium ion transmembrane transporter activity (GO:1901019)2.22628218
113regulation of calcium ion transmembrane transport (GO:1903169)2.22628218
114basement membrane organization (GO:0071711)2.21222156
115positive regulation of potassium ion transport (GO:0043268)2.20061538
116oligodendrocyte differentiation (GO:0048709)2.19870389
117axonal fasciculation (GO:0007413)2.19110189
118adult walking behavior (GO:0007628)2.18922458
119hemidesmosome assembly (GO:0031581)2.18845299
120chondroitin sulfate catabolic process (GO:0030207)2.18099571
121cAMP biosynthetic process (GO:0006171)2.17926131
122neuronal action potential propagation (GO:0019227)2.17594502
123regulation of cell communication by electrical coupling (GO:0010649)2.16114980
124import into cell (GO:0098657)2.16066375
125neuron recognition (GO:0008038)2.15959954
126positive regulation of cellular response to insulin stimulus (GO:1900078)2.15282670
127extracellular fibril organization (GO:0043206)2.15095882
128regulation of ARF GTPase activity (GO:0032312)2.14341618
129axon extension (GO:0048675)2.14224304
130neurotransmitter-gated ion channel clustering (GO:0072578)2.13804965
131actin-myosin filament sliding (GO:0033275)2.13543515
132muscle filament sliding (GO:0030049)2.13543515
133response to catecholamine (GO:0071869)2.13309368
134response to monoamine (GO:0071867)2.13309368
135auditory behavior (GO:0031223)2.12835109
136negative regulation of axonogenesis (GO:0050771)2.12121612
137response to epinephrine (GO:0071871)2.11452097
138adherens junction assembly (GO:0034333)2.11002574
139cerebellar granule cell differentiation (GO:0021707)2.10477902
140endocardial cushion development (GO:0003197)2.09669211
141cell volume homeostasis (GO:0006884)2.09224548
142negative regulation of smooth muscle cell migration (GO:0014912)2.09154583
143apical protein localization (GO:0045176)2.09129235
144cartilage development involved in endochondral bone morphogenesis (GO:0060351)2.08352454
145cortical cytoskeleton organization (GO:0030865)2.08004121
146cell migration in hindbrain (GO:0021535)2.07476540
147regulation of cardiac muscle cell contraction (GO:0086004)2.07323963
148regulation of neuronal synaptic plasticity (GO:0048168)2.06846705
149presynaptic membrane organization (GO:0097090)2.06565298
150astrocyte differentiation (GO:0048708)2.06182308
151positive regulation of axon extension (GO:0045773)2.06072515
152presynaptic membrane assembly (GO:0097105)2.05896810
153cGMP-mediated signaling (GO:0019934)2.04186409
154regulation of calcineurin-NFAT signaling cascade (GO:0070884)2.03357873
155glomerular basement membrane development (GO:0032836)2.02903545
156venous blood vessel morphogenesis (GO:0048845)2.02790008
157actin filament depolymerization (GO:0030042)2.02568828

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human2.64122109
2TRIM28_21343339_ChIP-Seq_HEK293_Human2.59308497
3SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.55716797
4* RNF2_18974828_ChIP-Seq_MESCs_Mouse2.50645402
5* EZH2_18974828_ChIP-Seq_MESCs_Mouse2.50645402
6DROSHA_22980978_ChIP-Seq_HELA_Human2.35034758
7SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.30851601
8SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.21142477
9* MTF2_20144788_ChIP-Seq_MESCs_Mouse2.13611641
10JARID2_20064375_ChIP-Seq_MESCs_Mouse2.13353921
11EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.06760997
12* JARID2_20075857_ChIP-Seq_MESCs_Mouse2.01018285
13EP300_21415370_ChIP-Seq_HL-1_Mouse1.96400932
14* EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.96299641
15* SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.95478455
16* EZH2_27304074_Chip-Seq_ESCs_Mouse1.94370576
17* SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.93808756
18* SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.92436831
19* WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.90509803
20* EZH2_27294783_Chip-Seq_ESCs_Mouse1.89573866
21MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.87289666
22* EED_16625203_ChIP-ChIP_MESCs_Mouse1.86259001
23* RNF2_27304074_Chip-Seq_ESCs_Mouse1.80260587
24PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.79811673
25* SUZ12_27294783_Chip-Seq_ESCs_Mouse1.78822105
26RARG_19884340_ChIP-ChIP_MEFs_Mouse1.75119894
27RARB_27405468_Chip-Seq_BRAIN_Mouse1.74998485
28KDM2B_26808549_Chip-Seq_K562_Human1.73062319
29ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.71246050
30TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.68091360
31* ESR2_21235772_ChIP-Seq_MCF-7_Human1.67949872
32STAT6_21828071_ChIP-Seq_BEAS2B_Human1.59921072
33CDX2_19796622_ChIP-Seq_MESCs_Mouse1.58068139
34TP63_17297297_ChIP-ChIP_HaCaT_Human1.55966855
35ZFP281_18757296_ChIP-ChIP_E14_Mouse1.53499494
36* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.48505641
37AR_21572438_ChIP-Seq_LNCaP_Human1.48456586
38* KDM2B_26808549_Chip-Seq_SUP-B15_Human1.47336938
39GBX2_23144817_ChIP-Seq_PC3_Human1.45569356
40ESR1_20079471_ChIP-ChIP_T-47D_Human1.45538596
41ERG_21242973_ChIP-ChIP_JURKAT_Human1.42983594
42PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.42898228
43SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.35587840
44SMAD_19615063_ChIP-ChIP_OVARY_Human1.31843101
45* TBX20_22328084_ChIP-Seq_HEART_Mouse1.30323664
46* TBX20_22080862_ChIP-Seq_HEART_Mouse1.30323664
47RING1B_27294783_Chip-Seq_ESCs_Mouse1.27960553
48NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.27189606
49PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.26661091
50VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.25646037
51* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.25013590
52* ESR1_21235772_ChIP-Seq_MCF-7_Human1.23129913
53NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.22359067
54CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.21152026
55RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.20648249
56* RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.18761806
57ZNF217_24962896_ChIP-Seq_MCF-7_Human1.18652045
58ZFP281_27345836_Chip-Seq_ESCs_Mouse1.17884248
59* KDM2B_26808549_Chip-Seq_DND41_Human1.17492349
60* DNAJC2_21179169_ChIP-ChIP_NT2_Human1.16961369
61ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.16818911
62* NFIB_24661679_ChIP-Seq_LUNG_Mouse1.16751279
63* TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.16452766
64TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.13328030
65* P300_27058665_Chip-Seq_ZR-75-30cells_Human1.12933587
66AHR_22903824_ChIP-Seq_MCF-7_Human1.11095728
67* TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.10812523
68* RING1B_27294783_Chip-Seq_NPCs_Mouse1.10699424
69SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.09686844
70* DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.07506673
71LXR_22292898_ChIP-Seq_THP-1_Human1.06147680
72* CLOCK_20551151_ChIP-Seq_293T_Human1.06016320
73GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.04781718
74TP53_20018659_ChIP-ChIP_R1E_Mouse1.04660468
75CTNNB1_20460455_ChIP-Seq_HCT116_Human1.04226558
76THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.04032170
77TP53_16413492_ChIP-PET_HCT116_Human1.03867677
78OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.02672751
79SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.01493546
80NR3C1_23031785_ChIP-Seq_PC12_Mouse1.01249586
81FOXO3_23340844_ChIP-Seq_DLD1_Human1.01059052
82* KDM2B_26808549_Chip-Seq_JURKAT_Human1.00879559
83CTCF_27219007_Chip-Seq_Bcells_Human1.00705453
84NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.00592497
85BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.00102728
86PPAR_26484153_Chip-Seq_NCI-H1993_Human1.00085059
87UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.99909630
88GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.99422404
89IKZF1_21737484_ChIP-ChIP_HCT116_Human0.98611105
90ISL1_27105846_Chip-Seq_CPCs_Mouse0.97529295
91* ELK3_25401928_ChIP-Seq_HUVEC_Human0.97181754
92* TP53_23651856_ChIP-Seq_MEFs_Mouse0.96671737
93* TET1_21490601_ChIP-Seq_MESCs_Mouse0.96552850
94MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.96310235
95CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.94736085
96CJUN_26792858_Chip-Seq_BT549_Human0.94635804
97REST_21632747_ChIP-Seq_MESCs_Mouse0.93557327
98* GATA2_21666600_ChIP-Seq_HMVEC_Human0.93511670
99RACK7_27058665_Chip-Seq_MCF-7_Human0.93291257
100SMAD4_21741376_ChIP-Seq_HESCs_Human0.92790291
101* PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.92407961
102SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.92371227
103NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.92229829
104NRF2_20460467_ChIP-Seq_MEFs_Mouse0.92229829
105ARNT_22903824_ChIP-Seq_MCF-7_Human0.91663585
106REST_18959480_ChIP-ChIP_MESCs_Mouse0.91374192
107SMC3_22415368_ChIP-Seq_MEFs_Mouse0.91346479
108SOX9_24532713_ChIP-Seq_HFSC_Mouse0.91137715
109WT1_19549856_ChIP-ChIP_CCG9911_Human0.90745811
110SMAD3_21741376_ChIP-Seq_HESCs_Human0.90185066
111PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.89616411
112TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse0.89483823
113* AR_19668381_ChIP-Seq_PC3_Human0.89460540
114* SOX2_21211035_ChIP-Seq_LN229_Gbm0.88778090
115CBX2_27304074_Chip-Seq_ESCs_Mouse0.87436548
116YAP1_20516196_ChIP-Seq_MESCs_Mouse0.83867665
117SMC1_22415368_ChIP-Seq_MEFs_Mouse0.83374715
118PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.83305847

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008438_abnormal_cutaneous_collagen3.89889786
2MP0000751_myopathy3.39969022
3MP0004859_abnormal_synaptic_plasticity3.18558913
4MP0002837_dystrophic_cardiac_calcinosis2.91747074
5MP0005623_abnormal_meninges_morphology2.73570189
6MP0003880_abnormal_central_pattern2.38256939
7MP0010368_abnormal_lymphatic_system2.33716799
8MP0000920_abnormal_myelination2.33225224
9MP0009780_abnormal_chondrocyte_physiolo2.29315900
10MP0004084_abnormal_cardiac_muscle2.25761587
11MP0004272_abnormal_basement_membrane2.12263029
12MP0005275_abnormal_skin_tensile2.07703508
13MP0004270_analgesia2.04664558
14MP0000749_muscle_degeneration1.93955644
15MP0000013_abnormal_adipose_tissue1.88214320
16MP0003705_abnormal_hypodermis_morpholog1.86878892
17MP0001958_emphysema1.85444036
18MP0004130_abnormal_muscle_cell1.81316659
19MP0004036_abnormal_muscle_relaxation1.80749071
20MP0004087_abnormal_muscle_fiber1.80564966
21MP0000747_muscle_weakness1.78031165
22MP0003950_abnormal_plasma_membrane1.73264400
23MP0001299_abnormal_eye_distance/1.71625562
24MP0004215_abnormal_myocardial_fiber1.71595532
25MP0003635_abnormal_synaptic_transmissio1.69674842
26MP0005257_abnormal_intraocular_pressure1.69286070
27MP0003283_abnormal_digestive_organ1.68620601
28MP0005330_cardiomyopathy1.68188394
29MP0000003_abnormal_adipose_tissue1.68101188
30MP0004145_abnormal_muscle_electrophysio1.67626300
31MP0005375_adipose_tissue_phenotype1.65256772
32MP0005666_abnormal_adipose_tissue1.64469994
33MP0005670_abnormal_white_adipose1.63941618
34MP0005595_abnormal_vascular_smooth1.62356932
35MP0004185_abnormal_adipocyte_glucose1.62284894
36MP0005423_abnormal_somatic_nervous1.61900025
37MP0003137_abnormal_impulse_conducting1.58264715
38MP0003690_abnormal_glial_cell1.58143227
39MP0003329_amyloid_beta_deposits1.53510878
40MP0006138_congestive_heart_failure1.52076150
41MP0005508_abnormal_skeleton_morphology1.46393627
42MP0003634_abnormal_glial_cell1.45015704
43MP0000767_abnormal_smooth_muscle1.44062745
44MP0000750_abnormal_muscle_regeneration1.41303766
45MP0002822_catalepsy1.41298235
46MP0005620_abnormal_muscle_contractility1.39220224
47MP0002972_abnormal_cardiac_muscle1.38982924
48MP0000759_abnormal_skeletal_muscle1.38612109
49MP0003279_aneurysm1.38532111
50MP0004858_abnormal_nervous_system1.37538072
51MP0002064_seizures1.36742959
52MP0008775_abnormal_heart_ventricle1.36198668
53MP0002272_abnormal_nervous_system1.35395360
54MP0008569_lethality_at_weaning1.35113374
55MP0001879_abnormal_lymphatic_vessel1.34519704
56MP0004233_abnormal_muscle_weight1.33808722
57MP0000733_abnormal_muscle_development1.32947512
58MP0000778_abnormal_nervous_system1.31009525
59MP0001486_abnormal_startle_reflex1.30795793
60MP0005503_abnormal_tendon_morphology1.29576749
61MP0003646_muscle_fatigue1.29513968
62MP0004885_abnormal_endolymph1.28430603
63MP0005171_absent_coat_pigmentation1.28044160
64MP0003879_abnormal_hair_cell1.27573702
65MP0005409_darkened_coat_color1.25933790
66MP0003091_abnormal_cell_migration1.25669172
67MP0009046_muscle_twitch1.22649677
68MP0009745_abnormal_behavioral_response1.19254567
69MP0004085_abnormal_heartbeat1.17105486
70MP0001502_abnormal_circadian_rhythm1.15597693
71MP0010630_abnormal_cardiac_muscle1.15455690
72MP0002106_abnormal_muscle_physiology1.14891691
73MP0002269_muscular_atrophy1.14183256
74MP0002108_abnormal_muscle_morphology1.13994463
75MP0002063_abnormal_learning/memory/cond1.12905236
76MP0003045_fibrosis1.12636368
77MP0005369_muscle_phenotype1.10165869
78MP0002896_abnormal_bone_mineralization1.09844249
79MP0000955_abnormal_spinal_cord1.09823283
80MP0005385_cardiovascular_system_phenoty1.08620560
81MP0001544_abnormal_cardiovascular_syste1.08620560
82MP0005023_abnormal_wound_healing1.07197411
83MP0001348_abnormal_lacrimal_gland1.04131802
84MP0003566_abnormal_cell_adhesion1.02470571
85MP0004484_altered_response_of1.02328770
86MP0005167_abnormal_blood-brain_barrier1.01689047
87MP0002734_abnormal_mechanical_nocicepti1.01075322
88MP0003385_abnormal_body_wall1.00138973
89MP0002295_abnormal_pulmonary_circulatio0.98660982
90MP0002249_abnormal_larynx_morphology0.98547520
91MP0004134_abnormal_chest_morphology0.98119022
92MP0002909_abnormal_adrenal_gland0.97769437
93MP0001849_ear_inflammation0.96229291
94MP0002733_abnormal_thermal_nociception0.93615377
95MP0004510_myositis0.92757160
96MP0002234_abnormal_pharynx_morphology0.92286258
97MP0010030_abnormal_orbit_morphology0.91923947
98MP0001542_abnormal_bone_strength0.90611191
99MP0002971_abnormal_brown_adipose0.87317301
100MP0002933_joint_inflammation0.85950291
101MP0001177_atelectasis0.85851720
102MP0004811_abnormal_neuron_physiology0.82915224
103MP0003632_abnormal_nervous_system0.82130953
104MP0002882_abnormal_neuron_morphology0.81584294
105MP0002066_abnormal_motor_capabilities/c0.81274189
106MP0003633_abnormal_nervous_system0.81152466
107MP0009384_cardiac_valve_regurgitation0.80489107
108MP0004924_abnormal_behavior0.79603079
109MP0005386_behavior/neurological_phenoty0.79603079
110MP0002572_abnormal_emotion/affect_behav0.79366284
111MP0002089_abnormal_postnatal_growth/wei0.79044044
112MP0002735_abnormal_chemical_nociception0.78426758
113MP0000534_abnormal_ureter_morphology0.78246627
114MP0001968_abnormal_touch/_nociception0.77817831
115MP0003631_nervous_system_phenotype0.77700594
116MP0000049_abnormal_middle_ear0.76696009
117MP0000163_abnormal_cartilage_morphology0.76169226
118MP0010386_abnormal_urinary_bladder0.73396496
119MP0000762_abnormal_tongue_morphology0.72919205
120MP0001501_abnormal_sleep_pattern0.72767717
121MP0001440_abnormal_grooming_behavior0.72725686
122MP0000462_abnormal_digestive_system0.72599017
123MP0008961_abnormal_basal_metabolism0.72055947
124MP0003942_abnormal_urinary_system0.71934087
125MP0009250_abnormal_appendicular_skeleto0.70630807
126MP0001970_abnormal_pain_threshold0.70280455
127MP0000467_abnormal_esophagus_morphology0.70047589

Predicted human phenotypes

RankGene SetZ-score
1Muscle fiber splitting (HP:0003555)4.26542304
2Premature rupture of membranes (HP:0001788)4.05214139
3Aortic aneurysm (HP:0004942)3.66583356
4Hyporeflexia of lower limbs (HP:0002600)3.56512886
5Difficulty running (HP:0009046)3.54322283
6Sudden death (HP:0001699)3.32960500
7Obstructive sleep apnea (HP:0002870)3.32862336
8Broad metatarsal (HP:0001783)3.31395879
9Shallow orbits (HP:0000586)3.20532463
10Protrusio acetabuli (HP:0003179)3.15943293
11Increased variability in muscle fiber diameter (HP:0003557)3.10841442
12Increased connective tissue (HP:0009025)3.07121795
13Myokymia (HP:0002411)3.07011163
14Vascular tortuosity (HP:0004948)3.02153575
15Onion bulb formation (HP:0003383)2.83001960
16Scapular winging (HP:0003691)2.77937777
17Arterial tortuosity (HP:0005116)2.77164779
18Atrial fibrillation (HP:0005110)2.74868741
19Aplasia involving bones of the extremities (HP:0009825)2.73990059
20Aplasia involving bones of the upper limbs (HP:0009823)2.73990059
21Aplasia of the phalanges of the hand (HP:0009802)2.73990059
22Abnormality of the calf musculature (HP:0001430)2.67414237
23Cerebral aneurysm (HP:0004944)2.66257425
24Exercise-induced myalgia (HP:0003738)2.62150470
25Distal upper limb amyotrophy (HP:0007149)2.62106453
26Upper limb amyotrophy (HP:0009129)2.62106453
27Bundle branch block (HP:0011710)2.61705281
28Type 1 muscle fiber predominance (HP:0003803)2.59319247
29Bladder diverticulum (HP:0000015)2.58843824
30Prolonged QT interval (HP:0001657)2.58237753
31Abnormality of skeletal muscle fiber size (HP:0012084)2.57907576
32Primary atrial arrhythmia (HP:0001692)2.57750904
33Wormian bones (HP:0002645)2.57585380
34Action tremor (HP:0002345)2.54828191
35Lower limb amyotrophy (HP:0007210)2.52850936
36Neurofibrillary tangles (HP:0002185)2.52757857
37Foot dorsiflexor weakness (HP:0009027)2.48588297
38Termporal pattern (HP:0011008)2.47690441
39Insidious onset (HP:0003587)2.47690441
40Supranuclear gaze palsy (HP:0000605)2.45770833
41Supraventricular arrhythmia (HP:0005115)2.45383367
42Cervical subluxation (HP:0003308)2.44771819
43Calf muscle hypertrophy (HP:0008981)2.42775035
44EMG: myopathic abnormalities (HP:0003458)2.42164062
45Supraventricular tachycardia (HP:0004755)2.41169900
46Ankle clonus (HP:0011448)2.39873805
47Abnormality of the foot musculature (HP:0001436)2.39682699
48Hypoventilation (HP:0002791)2.39423010
49Distal lower limb amyotrophy (HP:0008944)2.36844494
50Hypoplasia of the iris (HP:0007676)2.36429305
51Follicular hyperkeratosis (HP:0007502)2.36222531
52Wrist flexion contracture (HP:0001239)2.35536753
53Ankle contracture (HP:0006466)2.34183908
54Difficulty climbing stairs (HP:0003551)2.32827411
55Spinal rigidity (HP:0003306)2.32756537
56Bowel diverticulosis (HP:0005222)2.30199283
57Muscle hypertrophy of the lower extremities (HP:0008968)2.30012933
58Cerebral inclusion bodies (HP:0100314)2.27016490
59Ventricular tachycardia (HP:0004756)2.26869267
60Atrophic scars (HP:0001075)2.26409890
61Mitral regurgitation (HP:0001653)2.24307133
62Hyperacusis (HP:0010780)2.23743218
63Peripheral hypomyelination (HP:0007182)2.23279291
64Aortic dissection (HP:0002647)2.23067262
65Degeneration of the lateral corticospinal tracts (HP:0002314)2.21673893
66Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.21673893
67Myotonia (HP:0002486)2.21299257
68Fragile skin (HP:0001030)2.20295604
69Mildly elevated creatine phosphokinase (HP:0008180)2.20165686
70Genu recurvatum (HP:0002816)2.17573346
71Lipoatrophy (HP:0100578)2.17181589
72Aortic regurgitation (HP:0001659)2.16671926
73Hammertoe (HP:0001765)2.16302894
74Alacrima (HP:0000522)2.13096691
75Aneurysm (HP:0002617)2.13083078
76Exercise-induced muscle cramps (HP:0003710)2.11788230
77Right ventricular cardiomyopathy (HP:0011663)2.10534384
78Wide anterior fontanel (HP:0000260)2.08443503
79Coronal craniosynostosis (HP:0004440)2.07804597
80Limited hip movement (HP:0008800)2.07553902
81Ulnar bowing (HP:0003031)2.06233497
82Megalencephaly (HP:0001355)2.05672364
83Turricephaly (HP:0000262)2.04759647
84Stridor (HP:0010307)2.04279902
85Infantile muscular hypotonia (HP:0008947)2.04261136
86Bronchomalacia (HP:0002780)2.04210316
87Abnormality of dentin (HP:0010299)2.01895516
88Buphthalmos (HP:0000557)2.01148777
89Lymphangioma (HP:0100764)1.99788940
90Abnormality of the corticospinal tract (HP:0002492)1.99771746
91Gowers sign (HP:0003391)1.98852261
92Hypoplastic ischia (HP:0003175)1.97426974
93Ventricular fibrillation (HP:0001663)1.95864624
94Slender build (HP:0001533)1.95216111
95Dysmetria (HP:0001310)1.94860878
96Aplasia/Hypoplasia of the pubic bone (HP:0009104)1.94735655
97Neonatal short-limb short stature (HP:0008921)1.93359231
98Blue sclerae (HP:0000592)1.91575440
99Hyperextensible skin (HP:0000974)1.91564716
100Genetic anticipation (HP:0003743)1.89302512
101Syncope (HP:0001279)1.88392034
102Biconcave vertebral bodies (HP:0004586)1.87492981
103Joint laxity (HP:0001388)1.87076091
104Subaortic stenosis (HP:0001682)1.86559153
105Abnormality of the left ventricular outflow tract (HP:0011103)1.86559153
106Pulmonary artery stenosis (HP:0004415)1.86109898
107Abnormal atrioventricular conduction (HP:0005150)1.84967306
108Ventricular arrhythmia (HP:0004308)1.84383104
109Rapidly progressive (HP:0003678)1.83976513
110Round ear (HP:0100830)1.83738118
111Focal seizures (HP:0007359)1.83008188
112Achilles tendon contracture (HP:0001771)1.82206606
113Intention tremor (HP:0002080)1.81136986
114Overgrowth (HP:0001548)1.80843784
115Insomnia (HP:0100785)1.80820156
116Ectopia lentis (HP:0001083)1.80813437
117Hip contracture (HP:0003273)1.80234018
118Heart block (HP:0012722)1.79533501
119Abnormal EKG (HP:0003115)1.79432927
120Aortic valve stenosis (HP:0001650)1.79402996
121Abnormality of binocular vision (HP:0011514)1.78949743
122Diplopia (HP:0000651)1.78949743
123Dilatation of the ascending aorta (HP:0005111)1.78593208
124Mitral valve prolapse (HP:0001634)1.76043836
125Lower limb muscle weakness (HP:0007340)1.75327697
126Nuclear cataract (HP:0100018)1.74457527
127Urinary urgency (HP:0000012)1.74332608
128Renovascular hypertension (HP:0100817)1.74166587
129Flat cornea (HP:0007720)1.73611500
130Neoplasm of the heart (HP:0100544)1.73122480
131Axonal loss (HP:0003447)1.70238052
132Bradycardia (HP:0001662)1.69956078
133Soft skin (HP:0000977)1.69717025
134Overriding aorta (HP:0002623)1.69154747
135Joint stiffness (HP:0001387)1.68775534
136Torticollis (HP:0000473)1.67801499
137Atrioventricular block (HP:0001678)1.67767780
138Broad face (HP:0000283)1.67451588
139Sleep apnea (HP:0010535)1.67142687
140Vertebral compression fractures (HP:0002953)1.65446283
141Megalocornea (HP:0000485)1.64234042
142Abnormal eating behavior (HP:0100738)1.63399146
143Bell-shaped thorax (HP:0001591)1.63316552
144Mild short stature (HP:0003502)1.63063891
145Camptodactyly of toe (HP:0001836)1.59687550
146Protruding ear (HP:0000411)1.57187450

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TTN3.13104647
2TRIB32.98185654
3STK392.34247620
4DDR22.31598152
5PRKD32.29084565
6PHKG12.28212040
7PHKG22.28212040
8LMTK22.18898038
9PAK62.12075792
10EPHB12.02015315
11PDGFRA1.99955512
12ICK1.98344638
13RIPK11.97927342
14DMPK1.95121569
15TYRO31.86995734
16NTRK11.78243198
17EPHA41.70511087
18PKN11.68216629
19PAK31.50946543
20ROCK21.47797831
21WNK11.46471464
22FGFR21.44496963
23OXSR11.44250236
24CAMK1G1.42789580
25LIMK11.35120485
26SIK11.34462025
27MARK11.33466689
28BMX1.32620656
29MET1.32270748
30KSR21.29970531
31PRKD11.29169604
32AKT31.28331375
33UHMK11.24095685
34CAMK1D1.19766157
35MAP3K91.16865951
36NTRK31.16786578
37PKN21.15610549
38MARK21.15471101
39TGFBR21.13694572
40CAMKK11.12398718
41PRKCH1.11452271
42TESK11.10154390
43ROCK11.09611689
44PIK3CA1.09553785
45CAMK2D1.09333490
46CDK191.07386023
47WNK41.04698075
48CDK51.04556941
49PDGFRB1.04523454
50LATS21.04373457
51RPS6KA21.02076216
52RET1.00520703
53EPHA30.99845858
54EPHB20.99564207
55ILK0.95289083
56PRPF4B0.94535375
57TRPM70.94100502
58PTK2B0.93966364
59DAPK30.93632463
60MAP3K60.91820051
61EEF2K0.90631443
62CASK0.90194039
63NTRK20.90165890
64MAP3K70.89016975
65SGK4940.88626377
66SGK2230.88626377
67PDPK10.87036679
68PTK60.86698798
69PAK20.86351456
70CAMK2B0.83072852
71CDC42BPA0.81679054
72FER0.81627333
73ALK0.80351159
74PTK20.80050805
75MINK10.79139490
76MAP3K40.78644090
77TIE10.77192654
78DAPK20.76917265
79STK110.75327208
80STK380.74169761
81OBSCN0.73900777
82MAPKAPK30.73429211
83TAOK10.72336036
84MAPK120.71035311
85LATS10.69959361
86GRK50.69947556
87CDK150.69654297
88CDK140.69365183
89MAPKAPK50.68708548
90STK38L0.68195712
91FGFR10.67870106
92ERN10.67470015
93BCR0.66746750
94PRKD20.66306017
95NEK60.65394883
96MAPK70.64694487
97CAMK2G0.62956178
98CDK180.62697308
99ABL20.62311979
100CAMK2A0.61916834
101ADRBK10.60661420
102SGK20.60617443
103SGK30.60165997
104CDK11A0.60158688
105MYLK0.59795166
106PRKAA20.59107069
107FYN0.57373045
108MAPK40.56749544
109PRKAA10.54575495
110PRKCE0.52554285
111* MTOR0.51953538
112PRKCG0.51663989
113PINK10.51413493
114MAPK100.50720907
115PDK20.50502909
116CSNK1A1L0.50479807
117KSR10.49356096
118PDK10.48337789
119SRC0.47868639
120MAP2K10.47182719
121PRKG20.47157155
122CAMK10.47089570
123FGR0.46994228
124FGFR40.46585740
125ERBB20.45145758
126CAMK40.44403619
127SGK10.44038899
128MOS0.43619688
129RPS6KA30.42710417

Predicted pathways (KEGG)

RankGene SetZ-score
1Dilated cardiomyopathy_Homo sapiens_hsa054142.33408105
2Regulation of lipolysis in adipocytes_Homo sapiens_hsa049232.12157043
3Nitrogen metabolism_Homo sapiens_hsa009102.00617501
4Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.96718185
5Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.83305139
6ECM-receptor interaction_Homo sapiens_hsa045121.81820255
7Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.74576584
8Axon guidance_Homo sapiens_hsa043601.68376769
9Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.54187764
10Focal adhesion_Homo sapiens_hsa045101.53399291
11Circadian entrainment_Homo sapiens_hsa047131.49527846
12Gastric acid secretion_Homo sapiens_hsa049711.46130464
13Cardiac muscle contraction_Homo sapiens_hsa042601.42244965
14GABAergic synapse_Homo sapiens_hsa047271.40496136
15Glutamatergic synapse_Homo sapiens_hsa047241.39290551
16Gap junction_Homo sapiens_hsa045401.35683308
17Salivary secretion_Homo sapiens_hsa049701.35102947
18Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.29482840
19Olfactory transduction_Homo sapiens_hsa047401.29288632
20Morphine addiction_Homo sapiens_hsa050321.28311635
21Tight junction_Homo sapiens_hsa045301.28001319
22Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.27476271
23Renin secretion_Homo sapiens_hsa049241.23231756
24Oxytocin signaling pathway_Homo sapiens_hsa049211.22876860
25Fatty acid biosynthesis_Homo sapiens_hsa000611.22194526
26Cholinergic synapse_Homo sapiens_hsa047251.22063410
27Dorso-ventral axis formation_Homo sapiens_hsa043201.18718494
28Cocaine addiction_Homo sapiens_hsa050301.17367064
29Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.13280024
30Type II diabetes mellitus_Homo sapiens_hsa049301.12862410
31Phospholipase D signaling pathway_Homo sapiens_hsa040721.12778153
32Aldosterone synthesis and secretion_Homo sapiens_hsa049251.11718934
33Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.10067458
34Proteoglycans in cancer_Homo sapiens_hsa052051.09390364
35Histidine metabolism_Homo sapiens_hsa003401.09121247
36Dopaminergic synapse_Homo sapiens_hsa047281.08842236
37Glycosaminoglycan degradation_Homo sapiens_hsa005311.07918622
38Vascular smooth muscle contraction_Homo sapiens_hsa042701.07870926
39cAMP signaling pathway_Homo sapiens_hsa040241.06850001
40cGMP-PKG signaling pathway_Homo sapiens_hsa040221.05788962
41Synaptic vesicle cycle_Homo sapiens_hsa047211.05784467
42GnRH signaling pathway_Homo sapiens_hsa049121.05735872
43Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.03830048
44Renal cell carcinoma_Homo sapiens_hsa052111.02847252
45Long-term depression_Homo sapiens_hsa047301.00966065
46Glioma_Homo sapiens_hsa052140.99328937
47Adipocytokine signaling pathway_Homo sapiens_hsa049200.97911097
48Amoebiasis_Homo sapiens_hsa051460.97883862
49Protein digestion and absorption_Homo sapiens_hsa049740.97793764
50Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.97677062
51Long-term potentiation_Homo sapiens_hsa047200.97151496
52Insulin secretion_Homo sapiens_hsa049110.96968784
53Melanogenesis_Homo sapiens_hsa049160.96193297
54Estrogen signaling pathway_Homo sapiens_hsa049150.94930902
55Hedgehog signaling pathway_Homo sapiens_hsa043400.92677515
56ErbB signaling pathway_Homo sapiens_hsa040120.92610339
57Regulation of actin cytoskeleton_Homo sapiens_hsa048100.92566930
58Bile secretion_Homo sapiens_hsa049760.92306084
59Calcium signaling pathway_Homo sapiens_hsa040200.92268373
60Amphetamine addiction_Homo sapiens_hsa050310.90093065
61Endocytosis_Homo sapiens_hsa041440.89341080
62Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.88985558
63Rap1 signaling pathway_Homo sapiens_hsa040150.87956887
64Hippo signaling pathway_Homo sapiens_hsa043900.85431912
65Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.85227945
66Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.82310080
67AMPK signaling pathway_Homo sapiens_hsa041520.81025872
682-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.80392041
69Basal cell carcinoma_Homo sapiens_hsa052170.78616497
70Sphingolipid signaling pathway_Homo sapiens_hsa040710.76879802
71Fatty acid metabolism_Homo sapiens_hsa012120.76753576
72Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.76511634
73Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.76506726
74Thyroid hormone synthesis_Homo sapiens_hsa049180.76200662
75Ras signaling pathway_Homo sapiens_hsa040140.76172450
76Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.75163750
77PPAR signaling pathway_Homo sapiens_hsa033200.74520792
78Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.73766916
79VEGF signaling pathway_Homo sapiens_hsa043700.72249693
80MAPK signaling pathway_Homo sapiens_hsa040100.72044133
81Nicotine addiction_Homo sapiens_hsa050330.71735209
82Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.71083763
83Thyroid hormone signaling pathway_Homo sapiens_hsa049190.70711728
84Melanoma_Homo sapiens_hsa052180.69990425
85Viral myocarditis_Homo sapiens_hsa054160.69675907
86Circadian rhythm_Homo sapiens_hsa047100.68777500
87Serotonergic synapse_Homo sapiens_hsa047260.68510872
88AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.68098003
89Propanoate metabolism_Homo sapiens_hsa006400.66951101
90Insulin signaling pathway_Homo sapiens_hsa049100.66111129
91Longevity regulating pathway - mammal_Homo sapiens_hsa042110.65457945
92Phosphatidylinositol signaling system_Homo sapiens_hsa040700.64745767
93Ovarian steroidogenesis_Homo sapiens_hsa049130.64521839
94Insulin resistance_Homo sapiens_hsa049310.63721378
95Choline metabolism in cancer_Homo sapiens_hsa052310.63305836
96Notch signaling pathway_Homo sapiens_hsa043300.62496400
97Pancreatic secretion_Homo sapiens_hsa049720.62158022
98Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.61342687
99Platelet activation_Homo sapiens_hsa046110.61255880
100Neurotrophin signaling pathway_Homo sapiens_hsa047220.61037041
101PI3K-Akt signaling pathway_Homo sapiens_hsa041510.60849260
102Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.60843355
103Adherens junction_Homo sapiens_hsa045200.60469633
104beta-Alanine metabolism_Homo sapiens_hsa004100.60183405
105ABC transporters_Homo sapiens_hsa020100.58523100
106Pathways in cancer_Homo sapiens_hsa052000.58473610
107Wnt signaling pathway_Homo sapiens_hsa043100.57881406
108MicroRNAs in cancer_Homo sapiens_hsa052060.56923697
109Fatty acid elongation_Homo sapiens_hsa000620.56673579
110Lysine degradation_Homo sapiens_hsa003100.56536955
111Leukocyte transendothelial migration_Homo sapiens_hsa046700.56502314
112Taste transduction_Homo sapiens_hsa047420.55990862
113Glycerolipid metabolism_Homo sapiens_hsa005610.55826983
114Bladder cancer_Homo sapiens_hsa052190.53980611
115Small cell lung cancer_Homo sapiens_hsa052220.53819513
116Prion diseases_Homo sapiens_hsa050200.53571292
117Glucagon signaling pathway_Homo sapiens_hsa049220.52093385
118TGF-beta signaling pathway_Homo sapiens_hsa043500.49464407

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