PHTF1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1cilium or flagellum-dependent cell motility (GO:0001539)6.06012106
2negative regulation of multicellular organism growth (GO:0040015)4.46077985
3neural tube formation (GO:0001841)4.28663477
4acrosome assembly (GO:0001675)4.11265072
5axonemal dynein complex assembly (GO:0070286)4.09641717
6fusion of sperm to egg plasma membrane (GO:0007342)4.04101860
7regulation of memory T cell differentiation (GO:0043380)4.02979691
8cilium movement (GO:0003341)3.98838500
9behavioral response to ethanol (GO:0048149)3.97090465
10centriole replication (GO:0007099)3.89926888
11sex differentiation (GO:0007548)3.89381435
12regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.81758058
13epithelial cilium movement (GO:0003351)3.75035429
14cilium assembly (GO:0042384)3.66509814
15mitotic sister chromatid cohesion (GO:0007064)3.64773099
16cilium morphogenesis (GO:0060271)3.57849446
17nonmotile primary cilium assembly (GO:0035058)3.53116612
18epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.51325162
19sperm motility (GO:0030317)3.47030897
20microtubule polymerization or depolymerization (GO:0031109)3.44177727
21regulation of establishment of cell polarity (GO:2000114)3.43013639
22microtubule depolymerization (GO:0007019)3.41817316
23left/right axis specification (GO:0070986)3.36777793
24photoreceptor cell maintenance (GO:0045494)3.34287129
25acrosome reaction (GO:0007340)3.34091505
26negative regulation of cytosolic calcium ion concentration (GO:0051481)3.25825803
27kynurenine metabolic process (GO:0070189)3.24362198
28plasma membrane fusion (GO:0045026)3.23063709
29synaptonemal complex organization (GO:0070193)3.18150564
30behavioral response to nicotine (GO:0035095)3.18047887
31ventricular system development (GO:0021591)3.16656662
32tryptophan catabolic process (GO:0006569)3.15492295
33indole-containing compound catabolic process (GO:0042436)3.15492295
34indolalkylamine catabolic process (GO:0046218)3.15492295
35sperm-egg recognition (GO:0035036)3.15210316
36male meiosis (GO:0007140)3.14351491
37chromatin remodeling at centromere (GO:0031055)3.11505636
38regulation of microtubule-based movement (GO:0060632)3.07752563
39central nervous system projection neuron axonogenesis (GO:0021952)3.07620154
40regulation of MHC class I biosynthetic process (GO:0045343)3.03577542
41central nervous system neuron axonogenesis (GO:0021955)3.01649129
42negative regulation of DNA repair (GO:0045738)2.98403984
43pyrimidine nucleobase catabolic process (GO:0006208)2.98120822
44detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.97760948
45CENP-A containing nucleosome assembly (GO:0034080)2.95897740
46piRNA metabolic process (GO:0034587)2.95711022
47L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.94365728
48synaptonemal complex assembly (GO:0007130)2.93135310
49motile cilium assembly (GO:0044458)2.92583952
50regulation of ER to Golgi vesicle-mediated transport (GO:0060628)2.91727865
51olfactory bulb development (GO:0021772)2.90424139
52nuclear pore complex assembly (GO:0051292)2.90311204
53cell-cell recognition (GO:0009988)2.89943738
54negative regulation of inclusion body assembly (GO:0090084)2.89000574
55binding of sperm to zona pellucida (GO:0007339)2.88751285
56pyrimidine dimer repair (GO:0006290)2.87837819
57ADP metabolic process (GO:0046031)2.86811113
58synapsis (GO:0007129)2.86492814
59establishment of nucleus localization (GO:0040023)2.86165176
60DNA methylation involved in gamete generation (GO:0043046)2.85632572
61regulation of meiosis I (GO:0060631)2.84401047
62reciprocal meiotic recombination (GO:0007131)2.83742999
63reciprocal DNA recombination (GO:0035825)2.83742999
64cellular component assembly involved in morphogenesis (GO:0010927)2.82450429
65spermatid development (GO:0007286)2.81864013
66regulation of collateral sprouting (GO:0048670)2.81035444
67indolalkylamine metabolic process (GO:0006586)2.80967473
68peptidyl-lysine dimethylation (GO:0018027)2.79580701
69tryptophan metabolic process (GO:0006568)2.79064675
70male meiosis I (GO:0007141)2.78371829
71protein polyglutamylation (GO:0018095)2.77651611
72centriole assembly (GO:0098534)2.76699194
73somite rostral/caudal axis specification (GO:0032525)2.75804811
74preassembly of GPI anchor in ER membrane (GO:0016254)2.74735575
75negative regulation of fatty acid transport (GO:2000192)2.73723962
76seminiferous tubule development (GO:0072520)2.73242154
77tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.73133102
78RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.73133102
79resolution of meiotic recombination intermediates (GO:0000712)2.72931772
80cytoplasmic mRNA processing body assembly (GO:0033962)2.71173407
81replication fork processing (GO:0031297)2.71046332
82limb development (GO:0060173)2.70345223
83appendage development (GO:0048736)2.70345223
84L-methionine biosynthetic process (GO:0071265)2.69987010
85amino acid salvage (GO:0043102)2.69987010
86L-methionine salvage (GO:0071267)2.69987010
87regulation of establishment or maintenance of cell polarity (GO:0032878)2.69518695
88transmission of nerve impulse (GO:0019226)2.69152162
89somatic hypermutation of immunoglobulin genes (GO:0016446)2.67714734
90somatic diversification of immune receptors via somatic mutation (GO:0002566)2.67714734
91G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.67026912
92regulation of short-term neuronal synaptic plasticity (GO:0048172)2.66103287
93multicellular organism reproduction (GO:0032504)2.63601552
94calcium ion-dependent exocytosis (GO:0017156)2.63214167
95intraciliary transport (GO:0042073)2.62066717
96genitalia morphogenesis (GO:0035112)2.62049866
97locomotory exploration behavior (GO:0035641)2.59879601
98neuronal action potential propagation (GO:0019227)2.58843686
99meiotic chromosome segregation (GO:0045132)2.58235298
100adult walking behavior (GO:0007628)2.57292386
101synaptic transmission, cholinergic (GO:0007271)2.52733225
102histone exchange (GO:0043486)2.52405779
103spermatid nucleus differentiation (GO:0007289)2.50656034
104pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.50045460
105left/right pattern formation (GO:0060972)2.49901333
106response to X-ray (GO:0010165)2.48965709
107regulation of centriole replication (GO:0046599)2.48721612
108translesion synthesis (GO:0019985)2.48698110
109L-fucose catabolic process (GO:0042355)2.47756906
110fucose catabolic process (GO:0019317)2.47756906
111L-fucose metabolic process (GO:0042354)2.47756906
112cell wall macromolecule metabolic process (GO:0044036)2.47102281
113cell wall macromolecule catabolic process (GO:0016998)2.47102281
114photoreceptor cell development (GO:0042461)2.46741320
115smoothened signaling pathway (GO:0007224)2.45824656
116microtubule bundle formation (GO:0001578)2.45373706
117recombinational repair (GO:0000725)2.45033146
118retinal cone cell development (GO:0046549)2.44893061
119negative regulation of mast cell activation (GO:0033004)2.44810037
120synaptic vesicle maturation (GO:0016188)2.43900095
121protein neddylation (GO:0045116)2.43412651
122negative regulation of organelle assembly (GO:1902116)2.42370461
123centrosome duplication (GO:0051298)2.42148761
124body morphogenesis (GO:0010171)2.42075592
125nuclear pore organization (GO:0006999)2.41899965
126positive regulation of DNA damage response, signal transduction by p53 class mediator (GO:0043517)2.41204422
127embryonic body morphogenesis (GO:0010172)2.39591401
128glutamate secretion (GO:0014047)2.38032790
129monoubiquitinated protein deubiquitination (GO:0035520)2.37473833
130regulation of DNA endoreduplication (GO:0032875)2.34814681
131cerebellar Purkinje cell differentiation (GO:0021702)2.33925672
132cellular potassium ion homeostasis (GO:0030007)2.33239200
133positive regulation of signal transduction by p53 class mediator (GO:1901798)2.29162820
134positive regulation of calcium ion-dependent exocytosis (GO:0045956)2.27971027
135regulation of cilium movement (GO:0003352)2.27061488
136axoneme assembly (GO:0035082)2.26080055
137positive regulation of excitatory postsynaptic membrane potential (GO:2000463)2.17966964
138microtubule-based movement (GO:0007018)2.17185443
139positive regulation of vesicle fusion (GO:0031340)2.16769942
140pore complex assembly (GO:0046931)2.16065480
141protein localization to cilium (GO:0061512)2.13228459
142innervation (GO:0060384)2.11455689
143glucocorticoid receptor signaling pathway (GO:0042921)2.11089334
144membrane depolarization during action potential (GO:0086010)2.10743989
145synaptic vesicle docking involved in exocytosis (GO:0016081)2.10685362
146reproduction (GO:0000003)2.07791284
147microtubule severing (GO:0051013)2.07149108
148embryonic viscerocranium morphogenesis (GO:0048703)2.05287633
149gene silencing by RNA (GO:0031047)2.05269385
150chromosome organization involved in meiosis (GO:0070192)2.04987971
151exploration behavior (GO:0035640)2.04880275
152sister chromatid cohesion (GO:0007062)2.04724458
153regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act2.04148782
154synaptic vesicle exocytosis (GO:0016079)2.03667535
155layer formation in cerebral cortex (GO:0021819)2.02111943
156pre-miRNA processing (GO:0031054)2.01548958
157regulation of sister chromatid cohesion (GO:0007063)2.01036549
158establishment of protein localization to Golgi (GO:0072600)2.00563142
159cell recognition (GO:0008037)2.00079278
160retrograde transport, vesicle recycling within Golgi (GO:0000301)1.98894961
161peptidyl-threonine modification (GO:0018210)1.98623809
162negative regulation of dendrite morphogenesis (GO:0050774)1.98247379
163nucleus localization (GO:0051647)1.98051773
164regulation of Rac protein signal transduction (GO:0035020)1.98043240
165histone H3-K9 demethylation (GO:0033169)1.96469610
166protein localization to synapse (GO:0035418)1.96248984
167peptidyl-threonine phosphorylation (GO:0018107)1.95684674
168positive regulation of macrophage activation (GO:0043032)1.95624062
169cellular process involved in reproduction in multicellular organism (GO:0022412)1.95155751
170signal complex assembly (GO:0007172)1.94717656
171regulation of histone H3-K9 methylation (GO:0051570)1.94558791
172regulation of RNA export from nucleus (GO:0046831)1.94538641
173neuron projection extension involved in neuron projection guidance (GO:1902284)1.94396052
174axon extension involved in axon guidance (GO:0048846)1.94396052
175regulation of glutamate receptor signaling pathway (GO:1900449)1.94326962
176vesicle transport along microtubule (GO:0047496)1.93292728
177positive regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060213)1.93262887
178regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060211)1.93262887
179cilium organization (GO:0044782)1.92513633
180positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO1.92473054
181regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:1900151)1.92473054

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.11705762
2RBPJ_22232070_ChIP-Seq_NCS_Mouse4.35411415
3VDR_22108803_ChIP-Seq_LS180_Human3.45071925
4IGF1R_20145208_ChIP-Seq_DFB_Human3.34747149
5HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse3.25798046
6BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.82211507
7ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.72969081
8SMAD_19615063_ChIP-ChIP_OVARY_Human2.40242587
9MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.29726240
10CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.14382858
11* ER_23166858_ChIP-Seq_MCF-7_Human1.94168469
12* SALL1_21062744_ChIP-ChIP_HESCs_Human1.90084181
13GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.87734015
14HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.87030421
15EGR1_19374776_ChIP-ChIP_THP-1_Human1.84926043
16IRF1_19129219_ChIP-ChIP_H3396_Human1.83804632
17AR_21572438_ChIP-Seq_LNCaP_Human1.82316197
18MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.78770207
19ZNF274_21170338_ChIP-Seq_K562_Hela1.76528207
20GBX2_23144817_ChIP-Seq_PC3_Human1.73687551
21E2F7_22180533_ChIP-Seq_HELA_Human1.71832080
22FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.71611353
23STAT6_21828071_ChIP-Seq_BEAS2B_Human1.67521250
24MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.63546173
25SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.62258664
26CTBP2_25329375_ChIP-Seq_LNCAP_Human1.61954210
27SMAD4_21799915_ChIP-Seq_A2780_Human1.59275706
28TP53_16413492_ChIP-PET_HCT116_Human1.58820356
29FUS_26573619_Chip-Seq_HEK293_Human1.58095955
30TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.51251628
31ZNF217_24962896_ChIP-Seq_MCF-7_Human1.49556512
32JARID2_20064375_ChIP-Seq_MESCs_Mouse1.49249651
33UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.48522076
34PIAS1_25552417_ChIP-Seq_VCAP_Human1.48401248
35E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.47072370
36* EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.45386863
37TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.44327958
38TAF15_26573619_Chip-Seq_HEK293_Human1.43844634
39KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.42962364
40DROSHA_22980978_ChIP-Seq_HELA_Human1.42097212
41GABP_17652178_ChIP-ChIP_JURKAT_Human1.41017735
42TP53_22573176_ChIP-Seq_HFKS_Human1.40880528
43ELK1_19687146_ChIP-ChIP_HELA_Human1.40519845
44EWS_26573619_Chip-Seq_HEK293_Human1.38687442
45* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.37173244
46SUZ12_27294783_Chip-Seq_NPCs_Mouse1.36731425
47E2F4_17652178_ChIP-ChIP_JURKAT_Human1.36708476
48SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.36525271
49MYC_18940864_ChIP-ChIP_HL60_Human1.36127745
50PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.35760981
51PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.35092263
52SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.34646994
53AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.34183641
54P300_19829295_ChIP-Seq_ESCs_Human1.33681349
55RNF2_27304074_Chip-Seq_ESCs_Mouse1.33333771
56WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.32345907
57SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.32076068
58POU3F2_20337985_ChIP-ChIP_501MEL_Human1.31855966
59RUNX2_22187159_ChIP-Seq_PCA_Human1.29798660
60STAT3_23295773_ChIP-Seq_U87_Human1.28082395
61PKCTHETA_26484144_Chip-Seq_BREAST_Human1.27302572
62EZH2_27294783_Chip-Seq_NPCs_Mouse1.26613920
63SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.26587605
64ARNT_22903824_ChIP-Seq_MCF-7_Human1.26104717
65CTBP1_25329375_ChIP-Seq_LNCAP_Human1.25595400
66EZH2_18974828_ChIP-Seq_MESCs_Mouse1.24941002
67RNF2_18974828_ChIP-Seq_MESCs_Mouse1.24941002
68RARB_27405468_Chip-Seq_BRAIN_Mouse1.24473209
69TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.22962900
70TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.22897038
71AR_25329375_ChIP-Seq_VCAP_Human1.22761104
72SMAD3_21741376_ChIP-Seq_EPCs_Human1.22604781
73TCF4_23295773_ChIP-Seq_U87_Human1.22390488
74ZFP57_27257070_Chip-Seq_ESCs_Mouse1.21623761
75NFE2_27457419_Chip-Seq_LIVER_Mouse1.21520603
76FLI1_21867929_ChIP-Seq_TH2_Mouse1.20919552
77PCGF2_27294783_Chip-Seq_NPCs_Mouse1.19167763
78TOP2B_26459242_ChIP-Seq_MCF-7_Human1.18715303
79DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.18639859
80STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.18576838
81EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.17791248
82NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.17554565
83FLI1_27457419_Chip-Seq_LIVER_Mouse1.17316473
84* KLF5_20875108_ChIP-Seq_MESCs_Mouse1.17306040
85POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.16148423
86TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.16148423
87GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.15526349
88REST_21632747_ChIP-Seq_MESCs_Mouse1.14778372
89TP53_18474530_ChIP-ChIP_U2OS_Human1.14393665
90SOX2_19829295_ChIP-Seq_ESCs_Human1.13813043
91NANOG_19829295_ChIP-Seq_ESCs_Human1.13813043
92CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.13746269
93MTF2_20144788_ChIP-Seq_MESCs_Mouse1.12949986
94POU5F1_16153702_ChIP-ChIP_HESCs_Human1.12687706
95* TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.12118278
96YAP1_20516196_ChIP-Seq_MESCs_Mouse1.11818839
97KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.11553244
98EZH2_27304074_Chip-Seq_ESCs_Mouse1.11075938
99SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.10478635
100RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.10171208
101EST1_17652178_ChIP-ChIP_JURKAT_Human1.10157904
102NANOG_18555785_Chip-Seq_ESCs_Mouse1.09957486
103CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.09946035
104SMAD3_21741376_ChIP-Seq_ESCs_Human1.09787614
105JARID2_20075857_ChIP-Seq_MESCs_Mouse1.09700680
106AHR_22903824_ChIP-Seq_MCF-7_Human1.09565109
107IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.09512003
108CBP_20019798_ChIP-Seq_JUKART_Human1.09512003
109SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.09454841
110BCAT_22108803_ChIP-Seq_LS180_Human1.09375328
111CBX2_27304074_Chip-Seq_ESCs_Mouse1.08657494
112WT1_19549856_ChIP-ChIP_CCG9911_Human1.07933264
113MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.06818532
114KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.04977210
115TAL1_26923725_Chip-Seq_HPCs_Mouse1.04551353
116RNF2_27304074_Chip-Seq_NSC_Mouse1.04517291
117SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.04109108
118SMAD4_21741376_ChIP-Seq_EPCs_Human1.03891709
119CRX_20693478_ChIP-Seq_RETINA_Mouse1.03852050
120VDR_23849224_ChIP-Seq_CD4+_Human1.03491524
121P53_22387025_ChIP-Seq_ESCs_Mouse1.03455851
122CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.03080273
123E2F1_18555785_Chip-Seq_ESCs_Mouse1.01666622
124PADI4_21655091_ChIP-ChIP_MCF-7_Human1.01576954
125TCF4_18268006_ChIP-ChIP_LS174T_Human1.01109679
126FOXA1_25329375_ChIP-Seq_VCAP_Human1.00808690
127FOXA1_27270436_Chip-Seq_PROSTATE_Human1.00808690
128FOXA1_21572438_ChIP-Seq_LNCaP_Human1.00742449
129NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.00590401
130FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human0.99727838
131EP300_21415370_ChIP-Seq_HL-1_Mouse0.99504605
132WT1_25993318_ChIP-Seq_PODOCYTE_Human0.98830645
133GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.98778854
134PCGF2_27294783_Chip-Seq_ESCs_Mouse0.98505481
135* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.98366003
136NR3C1_21868756_ChIP-Seq_MCF10A_Human0.97804301
137SOX9_26525672_Chip-Seq_HEART_Mouse0.97607570
138FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.97484316
139CDX2_19796622_ChIP-Seq_MESCs_Mouse0.97294635
140TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse0.96877901
141IKZF1_21737484_ChIP-ChIP_HCT116_Human0.96730570
142TCF4_22108803_ChIP-Seq_LS180_Human0.96507339
143MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.96224456
144CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.95934963
145NR3C1_23031785_ChIP-Seq_PC12_Mouse0.95762804
146BMI1_23680149_ChIP-Seq_NPCS_Mouse0.95693955
147CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons0.95661867
148NOTCH1_21737748_ChIP-Seq_TLL_Human0.95575196
149SOX2_21211035_ChIP-Seq_LN229_Gbm0.95348193
150PRDM14_20953172_ChIP-Seq_ESCs_Human0.92896279
151FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.92254830
152SUZ12_18555785_Chip-Seq_ESCs_Mouse0.91825673

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005410_abnormal_fertilization3.44871061
2MP0004859_abnormal_synaptic_plasticity2.92927285
3MP0002653_abnormal_ependyma_morphology2.87402032
4MP0006072_abnormal_retinal_apoptosis2.55729565
5MP0008877_abnormal_DNA_methylation2.51957125
6MP0000569_abnormal_digit_pigmentation2.49897998
7MP0003787_abnormal_imprinting2.41862959
8MP0001529_abnormal_vocalization2.27668993
9MP0005623_abnormal_meninges_morphology2.26058737
10MP0008058_abnormal_DNA_repair2.17119713
11MP0001984_abnormal_olfaction2.09994457
12MP0003880_abnormal_central_pattern2.04056127
13MP0005253_abnormal_eye_physiology2.02543247
14MP0003123_paternal_imprinting1.98932579
15MP0005551_abnormal_eye_electrophysiolog1.97413449
16MP0005646_abnormal_pituitary_gland1.96596930
17MP0006292_abnormal_olfactory_placode1.92011515
18MP0004808_abnormal_hematopoietic_stem1.90818182
19MP0006276_abnormal_autonomic_nervous1.81582580
20MP0002638_abnormal_pupillary_reflex1.80245972
21MP0003121_genomic_imprinting1.79152881
22MP0004270_analgesia1.77919821
23MP0003252_abnormal_bile_duct1.73902057
24MP0004133_heterotaxia1.73018554
25MP0003635_abnormal_synaptic_transmissio1.72441358
26MP0001486_abnormal_startle_reflex1.67690201
27MP0005076_abnormal_cell_differentiation1.67372085
28MP0001968_abnormal_touch/_nociception1.66390646
29MP0003718_maternal_effect1.63936879
30MP0003698_abnormal_male_reproductive1.61781580
31MP0003136_yellow_coat_color1.57248875
32MP0002938_white_spotting1.55923243
33MP0004147_increased_porphyrin_level1.55794937
34MP0002928_abnormal_bile_duct1.55552354
35MP0001293_anophthalmia1.55357784
36MP0002736_abnormal_nociception_after1.54012121
37MP0003122_maternal_imprinting1.53826828
38MP0009250_abnormal_appendicular_skeleto1.52804417
39MP0010234_abnormal_vibrissa_follicle1.51942296
40MP0001929_abnormal_gametogenesis1.47287863
41MP0006035_abnormal_mitochondrial_morpho1.46944125
42MP0002272_abnormal_nervous_system1.42057822
43MP0001299_abnormal_eye_distance/1.40852436
44MP0005645_abnormal_hypothalamus_physiol1.38745153
45MP0008057_abnormal_DNA_replication1.34452531
46MP0004858_abnormal_nervous_system1.33464752
47MP0005499_abnormal_olfactory_system1.31809085
48MP0005394_taste/olfaction_phenotype1.31809085
49MP0010352_gastrointestinal_tract_polyps1.31194497
50MP0002063_abnormal_learning/memory/cond1.31190077
51MP0003942_abnormal_urinary_system1.29544374
52MP0009046_muscle_twitch1.28765994
53MP0006054_spinal_hemorrhage1.28066509
54MP0002735_abnormal_chemical_nociception1.26679107
55MP0000534_abnormal_ureter_morphology1.26247497
56MP0003115_abnormal_respiratory_system1.26020818
57MP0003890_abnormal_embryonic-extraembry1.22092348
58MP0002282_abnormal_trachea_morphology1.21054710
59MP0009745_abnormal_behavioral_response1.20764495
60MP0008789_abnormal_olfactory_epithelium1.20392898
61MP0002837_dystrophic_cardiac_calcinosis1.18406071
62MP0002210_abnormal_sex_determination1.17525949
63MP0002102_abnormal_ear_morphology1.17524842
64MP0001501_abnormal_sleep_pattern1.16855131
65MP0000427_abnormal_hair_cycle1.16725543
66MP0003011_delayed_dark_adaptation1.16665862
67MP0005391_vision/eye_phenotype1.15618723
68MP0002752_abnormal_somatic_nervous1.11471911
69MP0000537_abnormal_urethra_morphology1.11453279
70MP0003119_abnormal_digestive_system1.10525872
71MP0000428_abnormal_craniofacial_morphol1.10010439
72MP0005195_abnormal_posterior_eye1.09329611
73MP0010030_abnormal_orbit_morphology1.09250379
74MP0004811_abnormal_neuron_physiology1.08935878
75MP0002734_abnormal_mechanical_nocicepti1.07342153
76MP0000778_abnormal_nervous_system1.07298884
77MP0000383_abnormal_hair_follicle1.06936704
78MP0008007_abnormal_cellular_replicative1.06347987
79MP0002572_abnormal_emotion/affect_behav1.05664793
80MP0002733_abnormal_thermal_nociception1.05086892
81MP0000372_irregular_coat_pigmentation1.04820279
82MP0009780_abnormal_chondrocyte_physiolo1.02820990
83MP0003937_abnormal_limbs/digits/tail_de1.00776491
84MP0002009_preneoplasia1.00561351
85MP0005503_abnormal_tendon_morphology1.00209149
86MP0003045_fibrosis0.99969971
87MP0002184_abnormal_innervation0.99834840
88MP0004134_abnormal_chest_morphology0.99578735
89MP0005084_abnormal_gallbladder_morpholo0.99265640
90MP0003935_abnormal_craniofacial_develop0.98478287
91MP0005423_abnormal_somatic_nervous0.98447441
92MP0008932_abnormal_embryonic_tissue0.97816803
93MP0002177_abnormal_outer_ear0.97633614
94MP0002877_abnormal_melanocyte_morpholog0.96527181
95MP0002160_abnormal_reproductive_system0.95461024
96MP0004142_abnormal_muscle_tone0.95214418
97MP0003385_abnormal_body_wall0.95199479
98MP0010386_abnormal_urinary_bladder0.94421489
99MP0010094_abnormal_chromosome_stability0.93276935
100MP0000049_abnormal_middle_ear0.92321064
101MP0001970_abnormal_pain_threshold0.91783088
102MP0003755_abnormal_palate_morphology0.90729180
103MP0001145_abnormal_male_reproductive0.90717137
104MP0002233_abnormal_nose_morphology0.90395165
105MP0002116_abnormal_craniofacial_bone0.90233599
106MP0002882_abnormal_neuron_morphology0.89351319
107MP0008569_lethality_at_weaning0.87272694
108MP0002161_abnormal_fertility/fecundity0.86846294
109MP0002109_abnormal_limb_morphology0.86736822
110MP0002751_abnormal_autonomic_nervous0.86245130
111MP0002234_abnormal_pharynx_morphology0.86187413
112MP0001963_abnormal_hearing_physiology0.86001086
113MP0003861_abnormal_nervous_system0.85818596
114MP0009697_abnormal_copulation0.85210334
115MP0005386_behavior/neurological_phenoty0.85206925
116MP0004924_abnormal_behavior0.85206925
117MP0000358_abnormal_cell_content/0.85118986
118MP0002557_abnormal_social/conspecific_i0.84302834
119MP0002067_abnormal_sensory_capabilities0.83915828
120MP0003091_abnormal_cell_migration0.83420660
121MP0004885_abnormal_endolymph0.83259306
122MP0000647_abnormal_sebaceous_gland0.83031733
123MP0000653_abnormal_sex_gland0.81592959
124MP0003646_muscle_fatigue0.80725140
125MP0001119_abnormal_female_reproductive0.80363184
126MP0008961_abnormal_basal_metabolism0.80322769
127MP0001485_abnormal_pinna_reflex0.80228440
128MP0002064_seizures0.80062963
129MP0009053_abnormal_anal_canal0.79100924
130MP0001270_distended_abdomen0.78997191
131MP0001188_hyperpigmentation0.78811632
132MP0005248_abnormal_Harderian_gland0.78316894
133MP0001958_emphysema0.77618154
134MP0004742_abnormal_vestibular_system0.77200451
135MP0000026_abnormal_inner_ear0.76043933
136MP0000631_abnormal_neuroendocrine_gland0.74779035
137MP0005389_reproductive_system_phenotype0.74266773
138MP0003300_gastrointestinal_ulcer0.73999221
139MP0000432_abnormal_head_morphology0.73725885
140MP0001986_abnormal_taste_sensitivity0.73256509
141MP0002152_abnormal_brain_morphology0.72706878
142MP0002396_abnormal_hematopoietic_system0.72472268
143MP0000703_abnormal_thymus_morphology0.72408734
144MP0002084_abnormal_developmental_patter0.72351169
145MP0004233_abnormal_muscle_weight0.72271556
146MP0001177_atelectasis0.71415632
147MP0002114_abnormal_axial_skeleton0.70345537
148MP0003943_abnormal_hepatobiliary_system0.70225115
149MP0000955_abnormal_spinal_cord0.70011247
150MP0010307_abnormal_tumor_latency0.69546081
151MP0002095_abnormal_skin_pigmentation0.68488190
152MP0003283_abnormal_digestive_organ0.68258837
153MP0010678_abnormal_skin_adnexa0.67974522

Predicted human phenotypes

RankGene SetZ-score
1Respiratory insufficiency due to defective ciliary clearance (HP:0200073)4.96430065
2Dynein arm defect of respiratory motile cilia (HP:0012255)4.31969462
3Absent/shortened dynein arms (HP:0200106)4.31969462
4Pancreatic cysts (HP:0001737)4.21837907
5Medial flaring of the eyebrow (HP:0010747)4.10139611
6Abnormal respiratory motile cilium physiology (HP:0012261)4.03778448
7Congenital primary aphakia (HP:0007707)3.61589465
8Gait imbalance (HP:0002141)3.61047075
9Abnormal ciliary motility (HP:0012262)3.54304081
10Rhinitis (HP:0012384)3.33686901
11Nephrogenic diabetes insipidus (HP:0009806)3.23881001
12Abnormal respiratory motile cilium morphology (HP:0005938)3.08805953
13Abnormal respiratory epithelium morphology (HP:0012253)3.08805953
14Action tremor (HP:0002345)3.07868751
15Genital tract atresia (HP:0001827)2.95216126
16Vaginal atresia (HP:0000148)2.90390901
17Pendular nystagmus (HP:0012043)2.71500929
18Nephronophthisis (HP:0000090)2.69406490
19Bile duct proliferation (HP:0001408)2.63800734
20Abnormal biliary tract physiology (HP:0012439)2.63800734
21Chronic hepatic failure (HP:0100626)2.61815109
22Absent frontal sinuses (HP:0002688)2.60914298
23Nasal polyposis (HP:0100582)2.59895650
24Sclerocornea (HP:0000647)2.59089177
25Dialeptic seizures (HP:0011146)2.57512041
26Poor coordination (HP:0002370)2.56229803
27Abnormality of the renal cortex (HP:0011035)2.48882803
28Anencephaly (HP:0002323)2.48770737
29Chronic bronchitis (HP:0004469)2.46112367
30Oculomotor apraxia (HP:0000657)2.45189276
31Abnormality of macular pigmentation (HP:0008002)2.44132583
32Fibular hypoplasia (HP:0003038)2.36024806
33Absence seizures (HP:0002121)2.35916324
34Chromsome breakage (HP:0040012)2.30419155
35Congenital hepatic fibrosis (HP:0002612)2.30148407
36Preaxial hand polydactyly (HP:0001177)2.29026725
37Retinitis pigmentosa (HP:0000510)2.28040417
38Chromosomal breakage induced by crosslinking agents (HP:0003221)2.27214178
39Dysmetric saccades (HP:0000641)2.27088512
40Dysdiadochokinesis (HP:0002075)2.26201958
41Bronchiectasis (HP:0002110)2.25224513
42Prostate neoplasm (HP:0100787)2.25169218
43Absent speech (HP:0001344)2.23919104
44Postaxial hand polydactyly (HP:0001162)2.23004896
45Volvulus (HP:0002580)2.19337225
46Abolished electroretinogram (ERG) (HP:0000550)2.17482288
47Supernumerary spleens (HP:0009799)2.15884815
48Abnormality of dentin (HP:0010299)2.14775349
49Broad foot (HP:0001769)2.14634267
50Abnormality of the renal medulla (HP:0100957)2.13264393
51Aplasia/Hypoplasia of the uvula (HP:0010293)2.12009825
52Molar tooth sign on MRI (HP:0002419)2.11889996
53Abnormality of midbrain morphology (HP:0002418)2.11889996
54Bowel diverticulosis (HP:0005222)2.08208384
55Infertility (HP:0000789)2.05862248
56Bronchitis (HP:0012387)2.05480607
57Aplasia/Hypoplasia of the tibia (HP:0005772)2.04672834
58Aganglionic megacolon (HP:0002251)2.04416199
59Rib fusion (HP:0000902)2.02638118
60Intestinal atresia (HP:0011100)2.01621224
61Thyroid-stimulating hormone excess (HP:0002925)2.00370154
62Microglossia (HP:0000171)1.98670343
63Astigmatism (HP:0000483)1.98395038
64Type II lissencephaly (HP:0007260)1.97147630
65Renal cortical cysts (HP:0000803)1.96433601
66Hyperglycinemia (HP:0002154)1.95861518
67Truncal obesity (HP:0001956)1.94680492
68Abnormality of the nasal mucosa (HP:0000433)1.94425022
69Cerebellar dysplasia (HP:0007033)1.94200274
70Decreased testicular size (HP:0008734)1.94161820
71Abnormality of the ileum (HP:0001549)1.93874625
72Dandy-Walker malformation (HP:0001305)1.93109077
73Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)1.90506703
74Abnormality of the labia minora (HP:0012880)1.90179765
75Febrile seizures (HP:0002373)1.89751099
76Optic nerve hypoplasia (HP:0000609)1.89447166
77Oligodactyly (hands) (HP:0001180)1.88921418
78Aplasia/Hypoplasia of the fibula (HP:0006492)1.88896792
79Short 4th metacarpal (HP:0010044)1.88020572
80Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.88020572
81Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.88006195
82Hyperacusis (HP:0010780)1.86124420
83Abnormality of oral frenula (HP:0000190)1.86042812
84Aplasia/Hypoplasia of the spleen (HP:0010451)1.84617908
85Inability to walk (HP:0002540)1.84358960
86Abnormality of the hepatic vasculature (HP:0006707)1.83339901
87Tubulointerstitial abnormality (HP:0001969)1.82548791
88Aplasia/Hypoplasia of the lens (HP:0008063)1.82234859
89Progressive inability to walk (HP:0002505)1.82188605
90Impaired smooth pursuit (HP:0007772)1.82166173
91Male pseudohermaphroditism (HP:0000037)1.81719057
92Specific learning disability (HP:0001328)1.80871835
9311 pairs of ribs (HP:0000878)1.80755401
94Asymmetry of the thorax (HP:0001555)1.80630766
95Congenital stationary night blindness (HP:0007642)1.79249372
96Pointed chin (HP:0000307)1.78973940
97Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.78894492
98Prominent nasal bridge (HP:0000426)1.78850284
99Recurrent bronchitis (HP:0002837)1.78392768
100Abnormality of chromosome stability (HP:0003220)1.78172157
101Chorioretinal atrophy (HP:0000533)1.77911638
102Meckel diverticulum (HP:0002245)1.77897551
103Focal seizures (HP:0007359)1.77616768
104Renal duplication (HP:0000075)1.77436869
105Severe visual impairment (HP:0001141)1.77424246
106Lissencephaly (HP:0001339)1.77305390
107Ankyloglossia (HP:0010296)1.77171761
108Tubular atrophy (HP:0000092)1.76722556
109Chronic sinusitis (HP:0011109)1.76601894
110Abnormality of the epiphyses of the phalanges of the hand (HP:0005920)1.76523636
111Buphthalmos (HP:0000557)1.76498030
112Short foot (HP:0001773)1.76420075
113Abnormality of the lower motor neuron (HP:0002366)1.76362966
114Abnormality of the frontal sinuses (HP:0002687)1.76291271
115Attenuation of retinal blood vessels (HP:0007843)1.75974235
116Aplasia/Hypoplasia of the tongue (HP:0010295)1.75845957
117Urinary bladder sphincter dysfunction (HP:0002839)1.75842590
118Hyperventilation (HP:0002883)1.74946116
119Bony spicule pigmentary retinopathy (HP:0007737)1.74498793
120Focal motor seizures (HP:0011153)1.74094015
121Shallow orbits (HP:0000586)1.72761285
122Tubulointerstitial nephritis (HP:0001970)1.72732665
123Aplasia involving bones of the upper limbs (HP:0009823)1.71220558
124Aplasia of the phalanges of the hand (HP:0009802)1.71220558
125Aplasia involving bones of the extremities (HP:0009825)1.71220558
126Atonic seizures (HP:0010819)1.71000265
127Progressive cerebellar ataxia (HP:0002073)1.68355631
128Renovascular hypertension (HP:0100817)1.67366817
129Increased nuchal translucency (HP:0010880)1.67358851
130Dislocated radial head (HP:0003083)1.67264158
131Abnormality of ocular smooth pursuit (HP:0000617)1.67056883
132Abnormality of the radial head (HP:0003995)1.66882914
133Inappropriate behavior (HP:0000719)1.65766004
134Abnormality of the epiphyses of the hand (HP:0005924)1.65134066
135Elfin facies (HP:0004428)1.65072990
136Urinary urgency (HP:0000012)1.64200135
137Genetic anticipation (HP:0003743)1.63851814
138Broad distal phalanx of finger (HP:0009836)1.63243767
139Syringomyelia (HP:0003396)1.62780007
140Spinal cord lesions (HP:0100561)1.62780007
141Narrow palate (HP:0000189)1.61966609
142Abnormality involving the epiphyses of the upper limbs (HP:0003839)1.61602334
143Macroorchidism (HP:0000053)1.58503404
144Deviation of the hallux (HP:0010051)1.58269740
145Hallux valgus (HP:0001822)1.57951964
146Aqueductal stenosis (HP:0002410)1.56254428
147True hermaphroditism (HP:0010459)1.53506684
148Papilledema (HP:0001085)1.53492854
149Pancreatic fibrosis (HP:0100732)1.51883674
150Short nail (HP:0001799)1.51843686
151Trigonocephaly (HP:0000243)1.51053721
152Subacute progressive viral hepatitis (HP:0006572)1.50747767
153Facial cleft (HP:0002006)1.50538338
154Missing ribs (HP:0000921)1.50457427
155Cystic liver disease (HP:0006706)1.50359166
156Sacral dimple (HP:0000960)1.50281803
157Overriding aorta (HP:0002623)1.49688139
158Obsessive-compulsive behavior (HP:0000722)1.49502531
159Short ribs (HP:0000773)1.49348208
160Occipital encephalocele (HP:0002085)1.48620386
161Broad palm (HP:0001169)1.47387751
162Renal dysplasia (HP:0000110)1.46533942
163Hypoplastic labia majora (HP:0000059)1.46434039
164Hip dysplasia (HP:0001385)1.46095244
165Down-sloping shoulders (HP:0200021)1.44761082
166Widely spaced teeth (HP:0000687)1.44275191
167Papillary thyroid carcinoma (HP:0002895)1.43700340
168Amyotrophic lateral sclerosis (HP:0007354)1.43217587
169Postaxial foot polydactyly (HP:0001830)1.42789196
170Bicuspid aortic valve (HP:0001647)1.42699422
171Smooth philtrum (HP:0000319)1.42576712
172Gaze-evoked nystagmus (HP:0000640)1.42236853

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDK193.50677182
2PDK32.90044472
3PDK42.90044472
4CDC72.85479258
5NTRK32.84603815
6NEK12.79509063
7PRKD32.70451114
8BCR2.68567734
9ADRBK22.50925727
10WNK32.46413548
11OXSR12.30371533
12MAP3K42.23467471
13MAP4K22.21753823
14PNCK2.21359056
15PLK42.20671353
16TRIM282.19968816
17TRIB32.15273657
18EPHA42.01117979
19PTK2B1.97616547
20MINK11.94249093
21PINK11.72677482
22SIK21.71731816
23MAP3K121.68620819
24DYRK31.67905553
25RIPK41.65362917
26MAP3K91.63560564
27ZAK1.60659638
28EEF2K1.56530896
29SRPK11.52734128
30KSR11.52687474
31SCYL21.52472548
32TYRO31.51090123
33PLK21.48165694
34ACVR1B1.46118520
35GRK11.43277355
36ERBB31.42101095
37NEK21.39846410
38CCNB11.39142216
39TESK11.38732731
40STK38L1.38389522
41TAOK31.30601790
42CAMKK11.30268971
43BRSK21.29881347
44DMPK1.29305882
45BMPR21.26867752
46CSNK1G31.25824195
47CAMK1G1.24979678
48BCKDK1.20806728
49CSNK1G11.20602428
50MAP3K21.18545765
51MAP2K71.18212758
52RET1.15983478
53PDGFRB1.15969204
54MAP2K41.14285307
55FGFR21.13386870
56MAP3K101.10759492
57DYRK21.09807002
58FRK1.09116748
59MKNK21.06146924
60VRK11.02819702
61PRKCH1.02204282
62STK381.02028934
63SGK21.01121890
64VRK20.98914694
65NTRK20.98225040
66PDK20.97683367
67PDGFRA0.97181722
68TAOK10.94065532
69MAPK130.92229113
70INSRR0.90689769
71PLK10.90416530
72TIE10.88981289
73MARK10.88311447
74KSR20.87159902
75LATS20.87140115
76MAP3K60.86096297
77PRKCG0.86072630
78CASK0.84503764
79CDK120.83899499
80FGFR30.81671121
81FES0.80350774
82RPS6KA40.78796815
83SGK30.78554033
84CDK60.77323902
85DDR20.76883866
86PASK0.71677393
87DAPK10.71131569
88CHEK20.70530026
89ADRBK10.69372646
90WNK10.68515025
91RAF10.68144469
92PBK0.67489201
93CDK50.67107522
94MKNK10.67049838
95SIK30.66814796
96STK160.66279721
97DAPK20.65476842
98HIPK20.65373653
99ALK0.65175982
100FER0.65127742
101PAK30.65049907
102IRAK10.64174048
103PRKCE0.63602719
104PKN20.63161040
105ATM0.62787574
106PDK10.62159239
107CAMKK20.62026456
108CSNK1G20.61685706
109DYRK1A0.61236077
110MARK20.60817324
111MARK30.60592139
112FGFR10.59835464
113TNIK0.59048530
114STK30.58000083
115CSNK1A1L0.57880784
116WEE10.56721549
117PLK30.56319279
118MAPK100.56277125
119BMPR1B0.56097816
120STK100.55170942
121CAMK2A0.54576511
122CDK80.54162348
123TSSK60.53446783
124ATR0.52524582
125MUSK0.52021232
126CHEK10.51940099
127ERBB20.50477603
128EIF2AK30.50381635
129TTK0.50255627
130PAK60.49059691
131BRD40.48637956
132DYRK1B0.48445727
133TXK0.48382058
134LATS10.47541931
135MST40.47037628
136NUAK10.46791551
137STK390.44145418
138SGK10.44143213
139RPS6KA20.43247763
140MAPKAPK50.43097285
141CSNK1A10.42379005
142MAPK150.42319399
143NTRK10.41627145
144MAPK80.40769215
145TGFBR10.39787519
146CDK90.39287301
147STK110.39186741
148BUB10.38391774
149PRKDC0.37366827
150AURKB0.36836548
151GSK3B0.36662456
152TAF10.34133969
153MAP3K70.34029800
154CDK180.33860640
155PKN10.32786705
156CDK140.31827804
157CSNK1D0.31329786
158EIF2AK10.30904292
159TNK20.30435234
160PRKACB0.29300122
161RPS6KA50.28325733
162CDK150.27729231
163PRKACA0.27213508

Predicted pathways (KEGG)

RankGene SetZ-score
1Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005633.28906003
2Synthesis and degradation of ketone bodies_Homo sapiens_hsa000723.21740767
3Fanconi anemia pathway_Homo sapiens_hsa034603.04156784
4Primary bile acid biosynthesis_Homo sapiens_hsa001202.85918732
5Non-homologous end-joining_Homo sapiens_hsa034502.82439018
6Homologous recombination_Homo sapiens_hsa034402.62722740
7Butanoate metabolism_Homo sapiens_hsa006502.44684691
8RNA polymerase_Homo sapiens_hsa030202.32216732
9Propanoate metabolism_Homo sapiens_hsa006402.25956488
10Phototransduction_Homo sapiens_hsa047442.19903463
11Basal transcription factors_Homo sapiens_hsa030222.18884065
12Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.99638882
13Long-term potentiation_Homo sapiens_hsa047201.92368383
14Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.89120227
15Protein export_Homo sapiens_hsa030601.86113546
16Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.83266898
17Amphetamine addiction_Homo sapiens_hsa050311.79697217
18Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.79618024
19Base excision repair_Homo sapiens_hsa034101.77087351
20Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.73199813
21Olfactory transduction_Homo sapiens_hsa047401.69347159
22Nucleotide excision repair_Homo sapiens_hsa034201.64955348
23Mismatch repair_Homo sapiens_hsa034301.61828708
24Nicotine addiction_Homo sapiens_hsa050331.56042561
25Circadian entrainment_Homo sapiens_hsa047131.55214975
26Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.50422770
27Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.50326600
28Dopaminergic synapse_Homo sapiens_hsa047281.45091637
29Renin secretion_Homo sapiens_hsa049241.44853068
30Tryptophan metabolism_Homo sapiens_hsa003801.42639664
31RNA degradation_Homo sapiens_hsa030181.41896881
32Steroid biosynthesis_Homo sapiens_hsa001001.41796503
33Cysteine and methionine metabolism_Homo sapiens_hsa002701.40097746
34Dorso-ventral axis formation_Homo sapiens_hsa043201.38942842
35Estrogen signaling pathway_Homo sapiens_hsa049151.31952787
36Glioma_Homo sapiens_hsa052141.27465549
37Salivary secretion_Homo sapiens_hsa049701.27156662
38Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.26740786
39Glutamatergic synapse_Homo sapiens_hsa047241.26289718
40Gastric acid secretion_Homo sapiens_hsa049711.25803269
41Purine metabolism_Homo sapiens_hsa002301.24161930
42Pyrimidine metabolism_Homo sapiens_hsa002401.23981079
43Phosphatidylinositol signaling system_Homo sapiens_hsa040701.23623259
44Oocyte meiosis_Homo sapiens_hsa041141.22935242
45Insulin secretion_Homo sapiens_hsa049111.22540870
46Aldosterone synthesis and secretion_Homo sapiens_hsa049251.21392600
47GnRH signaling pathway_Homo sapiens_hsa049121.20816089
48DNA replication_Homo sapiens_hsa030301.20480193
49Synaptic vesicle cycle_Homo sapiens_hsa047211.20279352
50Huntingtons disease_Homo sapiens_hsa050161.20209384
51Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.19735600
52Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.18311381
53Melanogenesis_Homo sapiens_hsa049161.18131935
54Cocaine addiction_Homo sapiens_hsa050301.17854266
55Steroid hormone biosynthesis_Homo sapiens_hsa001401.17394519
56Cholinergic synapse_Homo sapiens_hsa047251.15783604
57Morphine addiction_Homo sapiens_hsa050321.15668855
58Fatty acid elongation_Homo sapiens_hsa000621.15527578
59Selenocompound metabolism_Homo sapiens_hsa004501.15452186
60Neurotrophin signaling pathway_Homo sapiens_hsa047221.13567153
61Ether lipid metabolism_Homo sapiens_hsa005651.12958823
62Peroxisome_Homo sapiens_hsa041461.12655677
63Oxytocin signaling pathway_Homo sapiens_hsa049211.11794909
64Nitrogen metabolism_Homo sapiens_hsa009101.10806890
65Long-term depression_Homo sapiens_hsa047301.09991802
66Wnt signaling pathway_Homo sapiens_hsa043101.08337230
67Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.06513897
68Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.06491364
69Taste transduction_Homo sapiens_hsa047421.05227305
70Colorectal cancer_Homo sapiens_hsa052101.04841665
71Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.04187718
72RNA transport_Homo sapiens_hsa030131.04160840
73Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.00969853
74Fatty acid metabolism_Homo sapiens_hsa012121.00616645
75Gap junction_Homo sapiens_hsa045401.00461430
76T cell receptor signaling pathway_Homo sapiens_hsa046600.99302044
77Thyroid hormone signaling pathway_Homo sapiens_hsa049190.98203113
78Axon guidance_Homo sapiens_hsa043600.97237571
79Parkinsons disease_Homo sapiens_hsa050120.96618108
80VEGF signaling pathway_Homo sapiens_hsa043700.96527783
81Chronic myeloid leukemia_Homo sapiens_hsa052200.95756356
82Calcium signaling pathway_Homo sapiens_hsa040200.95735839
83MAPK signaling pathway_Homo sapiens_hsa040100.95520459
84Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.95488054
85AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.94189945
86ErbB signaling pathway_Homo sapiens_hsa040120.93695048
87Endometrial cancer_Homo sapiens_hsa052130.92670203
88cAMP signaling pathway_Homo sapiens_hsa040240.92578042
89cGMP-PKG signaling pathway_Homo sapiens_hsa040220.92175342
90Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.91989944
91Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.91910445
92Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.91055943
93Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.90113887
94Spliceosome_Homo sapiens_hsa030400.89308785
95Rap1 signaling pathway_Homo sapiens_hsa040150.89195362
96mRNA surveillance pathway_Homo sapiens_hsa030150.88724506
97Glucagon signaling pathway_Homo sapiens_hsa049220.88677086
98Non-small cell lung cancer_Homo sapiens_hsa052230.88357022
99Serotonergic synapse_Homo sapiens_hsa047260.87761776
100Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.86649551
101MicroRNAs in cancer_Homo sapiens_hsa052060.86581262
102Proteoglycans in cancer_Homo sapiens_hsa052050.86493414
103Hippo signaling pathway_Homo sapiens_hsa043900.85813279
104Platelet activation_Homo sapiens_hsa046110.85792957
105alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.85391483
106Alcoholism_Homo sapiens_hsa050340.84801718
107Proteasome_Homo sapiens_hsa030500.84007174
108Adherens junction_Homo sapiens_hsa045200.83870925
109GABAergic synapse_Homo sapiens_hsa047270.83806927
110Hedgehog signaling pathway_Homo sapiens_hsa043400.83302160
111Pancreatic cancer_Homo sapiens_hsa052120.83230408
112Linoleic acid metabolism_Homo sapiens_hsa005910.83200923
113Thyroid hormone synthesis_Homo sapiens_hsa049180.82889067
114Oxidative phosphorylation_Homo sapiens_hsa001900.81999069
115Inositol phosphate metabolism_Homo sapiens_hsa005620.81979043
116Focal adhesion_Homo sapiens_hsa045100.81957232
117Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.80403927
118Basal cell carcinoma_Homo sapiens_hsa052170.80173479
119Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.78000099
120Melanoma_Homo sapiens_hsa052180.77818731
121Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.77717979
122HTLV-I infection_Homo sapiens_hsa051660.77669129
123N-Glycan biosynthesis_Homo sapiens_hsa005100.77007384
124Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.76624142
125Retinol metabolism_Homo sapiens_hsa008300.76409381
126Cell cycle_Homo sapiens_hsa041100.75911059
127Thyroid cancer_Homo sapiens_hsa052160.74616628
128Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.73531933
129Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.73303948
130B cell receptor signaling pathway_Homo sapiens_hsa046620.73046574
131Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.72473647
132ECM-receptor interaction_Homo sapiens_hsa045120.71626374
133Prolactin signaling pathway_Homo sapiens_hsa049170.71255199
134Metabolic pathways_Homo sapiens_hsa011000.70860889
135ABC transporters_Homo sapiens_hsa020100.70688096
136Fatty acid degradation_Homo sapiens_hsa000710.70162539
137Phospholipase D signaling pathway_Homo sapiens_hsa040720.70077387
138Circadian rhythm_Homo sapiens_hsa047100.70065666
139Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.69827599
140Prostate cancer_Homo sapiens_hsa052150.69655754
141Carbohydrate digestion and absorption_Homo sapiens_hsa049730.68999764
142Glutathione metabolism_Homo sapiens_hsa004800.68555618
143Chemical carcinogenesis_Homo sapiens_hsa052040.68324842
144Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.68232448
145TGF-beta signaling pathway_Homo sapiens_hsa043500.67878030
146Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.67226483
147Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.66942190
148mTOR signaling pathway_Homo sapiens_hsa041500.66580033
149Hepatitis B_Homo sapiens_hsa051610.66413332
150Ras signaling pathway_Homo sapiens_hsa040140.65938122
151Regulation of actin cytoskeleton_Homo sapiens_hsa048100.64790573
152p53 signaling pathway_Homo sapiens_hsa041150.64329991
153Type II diabetes mellitus_Homo sapiens_hsa049300.64127428
154Choline metabolism in cancer_Homo sapiens_hsa052310.63460779
155Viral carcinogenesis_Homo sapiens_hsa052030.63201961
156Fatty acid biosynthesis_Homo sapiens_hsa000610.63095406
157Pentose and glucuronate interconversions_Homo sapiens_hsa000400.62244914
158Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.62141406
159Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.62106654
160Pathways in cancer_Homo sapiens_hsa052000.62055776
161Vascular smooth muscle contraction_Homo sapiens_hsa042700.60873798
162Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.60725766
163beta-Alanine metabolism_Homo sapiens_hsa004100.60158388
164One carbon pool by folate_Homo sapiens_hsa006700.59926350
165Renal cell carcinoma_Homo sapiens_hsa052110.59222983
166Transcriptional misregulation in cancer_Homo sapiens_hsa052020.58749957
167Small cell lung cancer_Homo sapiens_hsa052220.58383666
168Caffeine metabolism_Homo sapiens_hsa002320.58123454
169Pyruvate metabolism_Homo sapiens_hsa006200.57910662
170Glycosaminoglycan degradation_Homo sapiens_hsa005310.56616128
171Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.56593566
172Regulation of autophagy_Homo sapiens_hsa041400.47368704
173Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.34587728
174Alzheimers disease_Homo sapiens_hsa050100.33204738

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