PI16

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan (GO:0019800)5.92915226
2vitamin A metabolic process (GO:0006776)5.85082141
3regulation of skeletal muscle contraction (GO:0014819)5.43416692
4muscle filament sliding (GO:0030049)5.26641372
5actin-myosin filament sliding (GO:0033275)5.26641372
6sarcomere organization (GO:0045214)5.17050447
7cardiac myofibril assembly (GO:0055003)4.79696185
8glomerular basement membrane development (GO:0032836)4.76654178
9myofibril assembly (GO:0030239)4.63691672
10plasma membrane repair (GO:0001778)4.53910366
11actin-mediated cell contraction (GO:0070252)4.48247690
12protein-chromophore linkage (GO:0018298)4.45363821
13protein heterotrimerization (GO:0070208)4.42758300
14glomerular visceral epithelial cell development (GO:0072015)4.35816582
15cellular response to electrical stimulus (GO:0071257)4.34562448
16extracellular fibril organization (GO:0043206)4.13070303
17keratan sulfate catabolic process (GO:0042340)3.99433454
18barbed-end actin filament capping (GO:0051016)3.90973275
19positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)3.87675467
20oxygen transport (GO:0015671)3.84000190
21glomerular epithelial cell development (GO:0072310)3.83460027
22bundle of His cell to Purkinje myocyte communication (GO:0086069)3.71205790
23actin filament-based movement (GO:0030048)3.63030665
24venous blood vessel morphogenesis (GO:0048845)3.62399171
25regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)3.58946115
26collagen fibril organization (GO:0030199)3.58275773
27negative regulation of potassium ion transmembrane transporter activity (GO:1901017)3.54611735
28fibril organization (GO:0097435)3.52753659
29regulation of calcineurin-NFAT signaling cascade (GO:0070884)3.46292341
30extracellular matrix assembly (GO:0085029)3.44428618
31retina vasculature morphogenesis in camera-type eye (GO:0061299)3.42392564
32regulation of rhodopsin mediated signaling pathway (GO:0022400)3.41248044
33actomyosin structure organization (GO:0031032)3.40288315
34vascular endothelial growth factor signaling pathway (GO:0038084)3.38873692
35regulation of p38MAPK cascade (GO:1900744)3.38592926
36cardiac muscle cell development (GO:0055013)3.38440185
37detection of light stimulus involved in visual perception (GO:0050908)3.35837927
38detection of light stimulus involved in sensory perception (GO:0050962)3.35837927
39virion attachment to host cell (GO:0019062)3.35616152
40adhesion of symbiont to host cell (GO:0044650)3.35616152
41collagen metabolic process (GO:0032963)3.34774752
42regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)3.34609565
43cardiac muscle contraction (GO:0060048)3.34433010
44cell migration involved in heart development (GO:0060973)3.32214541
45multicellular organismal macromolecule metabolic process (GO:0044259)3.29998489
46dermatan sulfate biosynthetic process (GO:0030208)3.29219528
47carnitine shuttle (GO:0006853)3.28468680
48regulation of actin filament-based movement (GO:1903115)3.25808451
49cardiac cell development (GO:0055006)3.24389584
50skeletal muscle adaptation (GO:0043501)3.24380577
51sarcoplasmic reticulum calcium ion transport (GO:0070296)3.21806966
52cardiac muscle tissue morphogenesis (GO:0055008)3.20563314
53dermatan sulfate metabolic process (GO:0030205)3.20411776
54regulation of relaxation of muscle (GO:1901077)3.17056846
55collagen catabolic process (GO:0030574)3.17004140
56heart trabecula formation (GO:0060347)3.16794001
57lymph vessel development (GO:0001945)3.13930701
58negative regulation of smooth muscle cell migration (GO:0014912)3.13106349
59striated muscle hypertrophy (GO:0014897)3.12810514
60blood vessel maturation (GO:0001955)3.11034278
61rhodopsin mediated signaling pathway (GO:0016056)3.10419554
62negative regulation of cartilage development (GO:0061037)3.10174939
63multicellular organismal metabolic process (GO:0044236)3.09959785
64regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO3.09849126
65detection of molecule of bacterial origin (GO:0032490)3.08097131
66striated muscle contraction (GO:0006941)3.05910370
67muscle tissue morphogenesis (GO:0060415)3.04877656
68multicellular organismal catabolic process (GO:0044243)3.03507241
69negative regulation of potassium ion transmembrane transport (GO:1901380)3.03446421
70regulation of extracellular matrix disassembly (GO:0010715)3.03304176
71regulation of sequestering of triglyceride (GO:0010889)3.01863390
72apoptotic cell clearance (GO:0043277)3.00566839
73type B pancreatic cell proliferation (GO:0044342)2.98445984
74glomerular filtration (GO:0003094)2.95897580
75skeletal muscle contraction (GO:0003009)2.93121524
76positive regulation of p38MAPK cascade (GO:1900745)2.91742380
77positive regulation of receptor recycling (GO:0001921)2.91521423
78negative regulation of gluconeogenesis (GO:0045721)2.91427879
79muscle hypertrophy (GO:0014896)2.90888984
80fatty acid transmembrane transport (GO:1902001)2.90067753
81regulation of striated muscle contraction (GO:0006942)2.89326567
82ventricular cardiac muscle tissue morphogenesis (GO:0055010)2.88570553
83cellular response to vascular endothelial growth factor stimulus (GO:0035924)2.88322645
84negative regulation of chondrocyte differentiation (GO:0032331)2.87054659
85chondroitin sulfate catabolic process (GO:0030207)2.86241196
86creatine metabolic process (GO:0006600)2.86059193
87trabecula formation (GO:0060343)2.85190126
88cartilage development involved in endochondral bone morphogenesis (GO:0060351)2.83462158
89negative regulation of smooth muscle cell proliferation (GO:0048662)2.83074809
90renal filtration (GO:0097205)2.82916301
91ventricular cardiac muscle cell action potential (GO:0086005)2.82809107
92adhesion of symbiont to host (GO:0044406)2.81365580
93desmosome organization (GO:0002934)2.81249835
94regulation of cell communication by electrical coupling (GO:0010649)2.80446989
95peptide cross-linking (GO:0018149)2.80419993
96sequestering of extracellular ligand from receptor (GO:0035581)2.79178119
97hemidesmosome assembly (GO:0031581)2.78839721
98negative regulation of Rho protein signal transduction (GO:0035024)2.78192401
99leukocyte migration involved in inflammatory response (GO:0002523)2.76848419
100stress fiber assembly (GO:0043149)2.73877897
101keratinization (GO:0031424)2.73474322
102cardiac muscle hypertrophy (GO:0003300)2.71479523
103regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314)2.71023395
104negative regulation of nitric-oxide synthase activity (GO:0051001)2.70211946
105negative regulation of stress fiber assembly (GO:0051497)2.70006266
106extracellular matrix disassembly (GO:0022617)2.68556384
107endothelial cell morphogenesis (GO:0001886)2.68048337
108negative regulation of platelet-derived growth factor receptor signaling pathway (GO:0010642)2.67469587
109gas transport (GO:0015669)2.67364204
110positive regulation of guanylate cyclase activity (GO:0031284)2.67197230
111endothelial cell chemotaxis (GO:0035767)2.66569158
112lung lobe morphogenesis (GO:0060463)2.66306389
113epithelial cell-cell adhesion (GO:0090136)2.65655738
114positive regulation of cholesterol efflux (GO:0010875)2.65389152
115mannose metabolic process (GO:0006013)2.64377814
116metanephric mesenchyme development (GO:0072075)2.64113633
117peripheral nervous system axon ensheathment (GO:0032292)2.63594549
118myelination in peripheral nervous system (GO:0022011)2.63594549
119endodermal cell differentiation (GO:0035987)2.62950120
120negative regulation of nitric oxide biosynthetic process (GO:0045019)2.62120448
121muscle contraction (GO:0006936)2.61732479
122regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)2.60427473
123skin morphogenesis (GO:0043589)2.59492269
124growth hormone secretion (GO:0030252)2.59444128
125adult heart development (GO:0007512)2.59438828
126atrioventricular valve morphogenesis (GO:0003181)2.56638661
127bone trabecula formation (GO:0060346)2.56130748
128regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)2.54932501
129glomerulus development (GO:0032835)2.53017948
130regulation of striated muscle cell apoptotic process (GO:0010662)2.52115936
131muscle system process (GO:0003012)2.51895395
132lipoxygenase pathway (GO:0019372)2.51450930
133cell proliferation involved in metanephros development (GO:0072203)2.50186696
134response to stimulus involved in regulation of muscle adaptation (GO:0014874)2.50076360
135kidney mesenchyme development (GO:0072074)2.47342210
136low-density lipoprotein particle clearance (GO:0034383)2.43312765
137insulin-like growth factor receptor signaling pathway (GO:0048009)2.43072899
138smooth muscle tissue development (GO:0048745)2.40908790
139cellular response to epinephrine stimulus (GO:0071872)2.39653316
140regulation of integrin-mediated signaling pathway (GO:2001044)2.37810961
141regulation of chemokine-mediated signaling pathway (GO:0070099)2.37758672
142regulation of guanylate cyclase activity (GO:0031282)2.36289509
143positive regulation of cholesterol transport (GO:0032376)2.35176846
144positive regulation of sterol transport (GO:0032373)2.35176846
145negative regulation of homotypic cell-cell adhesion (GO:0034111)2.33170246
146negative regulation of phosphatidylinositol 3-kinase signaling (GO:0014067)2.32023953
147angiogenesis involved in wound healing (GO:0060055)2.30725861
148positive regulation of membrane protein ectodomain proteolysis (GO:0051044)2.30011771
149protein trimerization (GO:0070206)2.29016478
150cell-substrate junction assembly (GO:0007044)2.28862651
151triglyceride catabolic process (GO:0019433)2.27823188
152regulation of peroxisome proliferator activated receptor signaling pathway (GO:0035358)2.27699371
153glycosaminoglycan catabolic process (GO:0006027)2.27472748
154negative regulation of chemokine production (GO:0032682)2.26943244
155negative regulation of BMP signaling pathway (GO:0030514)2.25875121
156substrate-dependent cell migration (GO:0006929)2.25077649
157extracellular matrix organization (GO:0030198)2.23594501
158surfactant homeostasis (GO:0043129)2.22804867
159phototransduction, visible light (GO:0007603)2.22789126
160extracellular structure organization (GO:0043062)2.22632784
161regulation of smooth muscle cell migration (GO:0014910)2.22334383
162cGMP-mediated signaling (GO:0019934)2.21887996
163positive regulation of extracellular matrix organization (GO:1903055)2.20714278
164positive regulation of macrophage derived foam cell differentiation (GO:0010744)2.19539249
165regulation of lipoprotein metabolic process (GO:0050746)2.18430139
166ovulation from ovarian follicle (GO:0001542)2.18102193
167regulation of membrane protein ectodomain proteolysis (GO:0051043)2.16908839
168blood vessel remodeling (GO:0001974)2.16774488
169neuron projection extension involved in neuron projection guidance (GO:1902284)2.16663102
170axon extension involved in axon guidance (GO:0048846)2.16663102
171vascular endothelial growth factor receptor signaling pathway (GO:0048010)2.15222851
172positive regulation of protein import into nucleus, translocation (GO:0033160)2.13960458
173fibroblast migration (GO:0010761)2.13451314

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TRIM28_21343339_ChIP-Seq_HEK293_Human3.94731950
2PPARG_19300518_ChIP-PET_3T3-L1_Mouse3.87075421
3BP1_19119308_ChIP-ChIP_Hs578T_Human3.75539151
4TP63_17297297_ChIP-ChIP_HaCaT_Human3.24184989
5RARG_19884340_ChIP-ChIP_MEFs_Mouse3.13138163
6EP300_21415370_ChIP-Seq_HL-1_Mouse2.55897431
7PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse2.51389256
8TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human2.41141794
9CDX2_19796622_ChIP-Seq_MESCs_Mouse2.24493589
10CLOCK_20551151_ChIP-Seq_293T_Human2.19408844
11ESR1_22446102_ChIP-Seq_UTERUS_Mouse2.15871383
12FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.09463654
13TBX20_22328084_ChIP-Seq_HEART_Mouse2.02712218
14TBX20_22080862_ChIP-Seq_HEART_Mouse2.02712218
15ESR2_21235772_ChIP-Seq_MCF-7_Human1.92883617
16ESR1_21235772_ChIP-Seq_MCF-7_Human1.90850686
17GATA2_21666600_ChIP-Seq_HMVEC_Human1.87200514
18THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.86558727
19CJUN_26792858_Chip-Seq_BT549_Human1.77340868
20BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.61283757
21EZH2_22144423_ChIP-Seq_EOC_Human1.57923061
22STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.57700903
23EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.56954253
24TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.55780232
25ESR1_20079471_ChIP-ChIP_T-47D_Human1.51754592
26DROSHA_22980978_ChIP-Seq_HELA_Human1.50365985
27CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.47305865
28ELK3_25401928_ChIP-Seq_HUVEC_Human1.45282831
29KDM2B_26808549_Chip-Seq_SUP-B15_Human1.43344514
30P63_26484246_Chip-Seq_KERATINOCYTES_Human1.42860725
31TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.42376839
32RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.41512454
33NFIB_24661679_ChIP-Seq_LUNG_Mouse1.40935009
34MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.39652790
35CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.34641647
36SOX9_24532713_ChIP-Seq_HFSC_Mouse1.34551676
37SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.33245063
38SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.30629131
39PPAR_26484153_Chip-Seq_NCI-H1993_Human1.25890856
40RNF2_18974828_ChIP-Seq_MESCs_Mouse1.25154366
41EZH2_18974828_ChIP-Seq_MESCs_Mouse1.25154366
42LXR_22292898_ChIP-Seq_THP-1_Human1.23368916
43MEF2A_21415370_ChIP-Seq_HL-1_Mouse1.21001151
44PPARG_20176806_ChIP-Seq_3T3-L1_Mouse1.19785284
45CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.17864395
46SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.17002208
47NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.15844878
48EED_16625203_ChIP-ChIP_MESCs_Mouse1.15749043
49SMC3_22415368_ChIP-Seq_MEFs_Mouse1.15410003
50NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.12903859
51SA1_22415368_ChIP-Seq_MEFs_Mouse1.12419241
52RUNX_20019798_ChIP-Seq_JUKART_Human1.11566131
53DNAJC2_21179169_ChIP-ChIP_NT2_Human1.10759895
54SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.10735022
55PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.09991771
56MTF2_20144788_ChIP-Seq_MESCs_Mouse1.08952091
57SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.08707987
58AHR_22903824_ChIP-Seq_MCF-7_Human1.08510117
59FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.07334884
60CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.07084074
61SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.06781240
62RNF2_27304074_Chip-Seq_ESCs_Mouse1.05943175
63RACK7_27058665_Chip-Seq_MCF-7_Human1.05807056
64WT1_19549856_ChIP-ChIP_CCG9911_Human1.03346462
65HIF1A_21447827_ChIP-Seq_MCF-7_Human1.03263716
66JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.02643281
67ZNF217_24962896_ChIP-Seq_MCF-7_Human1.01493104
68KDM2B_26808549_Chip-Seq_K562_Human1.01051407
69VDR_24787735_ChIP-Seq_THP-1_Human1.00643205
70TP53_16413492_ChIP-PET_HCT116_Human1.00554048
71VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.99595139
72NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.99567898
73KDM2B_26808549_Chip-Seq_DND41_Human0.99430804
74JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.99029839
75RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.98673911
76UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.98654069
77STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.97837913
78BRD4_25478319_ChIP-Seq_HGPS_Human0.97190545
79CTCF_27219007_Chip-Seq_Bcells_Human0.97185834
80ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.96979609
81SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.96418838
82TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse0.95002538
83* EZH2_27294783_Chip-Seq_ESCs_Mouse0.94553212
84FOXO3_23340844_ChIP-Seq_DLD1_Human0.93630616
85TP53_23651856_ChIP-Seq_MEFs_Mouse0.93164825
86SPI1_23127762_ChIP-Seq_K562_Human0.93001697
87* JARID2_20075857_ChIP-Seq_MESCs_Mouse0.92378819
88* PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.92221770
89* MYB_21317192_ChIP-Seq_ERMYB_Mouse0.92084462
90RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.91980663
91WT1_25993318_ChIP-Seq_PODOCYTE_Human0.91930957
92* SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.91889982
93TP53_18474530_ChIP-ChIP_U2OS_Human0.90908740
94TP53_20018659_ChIP-ChIP_R1E_Mouse0.90039796
95EGR1_19032775_ChIP-ChIP_M12_Human0.89940014
96SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse0.89649124
97WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.89483067
98EZH2_27304074_Chip-Seq_ESCs_Mouse0.89256204
99KDM2B_26808549_Chip-Seq_JURKAT_Human0.88286403
100* TP63_22573176_ChIP-Seq_HFKS_Human0.88239649
101SMAD_19615063_ChIP-ChIP_OVARY_Human0.88188113
102SMC1_22415368_ChIP-Seq_MEFs_Mouse0.88125109
103NR3C1_23031785_ChIP-Seq_PC12_Mouse0.88119809
104AR_21572438_ChIP-Seq_LNCaP_Human0.87169235
105* SUZ12_20075857_ChIP-Seq_MESCs_Mouse0.87064255
106* SUZ12_27294783_Chip-Seq_ESCs_Mouse0.87049715
107RXR_22158963_ChIP-Seq_LIVER_Mouse0.86313086
108NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.85113565
109NRF2_20460467_ChIP-Seq_MEFs_Mouse0.85113565
110ZNF263_19887448_ChIP-Seq_K562_Human0.84842563
111Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.84451347
112ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.84068773
113SMAD3_18955504_ChIP-ChIP_HaCaT_Human0.83594917
114SMAD2_18955504_ChIP-ChIP_HaCaT_Human0.83594917
115P300_27058665_Chip-Seq_ZR-75-30cells_Human0.83568547
116RUNX1_27514584_Chip-Seq_MCF-7_Human0.83443140
117CSB_26484114_Chip-Seq_FIBROBLAST_Human0.83278701
118SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.82770811
119PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse0.82655062
120CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.82317561
121RAD21_21589869_ChIP-Seq_MESCs_Mouse0.82277111
122* RING1B_27294783_Chip-Seq_ESCs_Mouse0.79077528
123LXR_22158963_ChIP-Seq_LIVER_Mouse0.78459794
124IRF1_21803131_ChIP-Seq_MONOCYTES_Human0.77147407

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003011_delayed_dark_adaptation7.98853034
2MP0008438_abnormal_cutaneous_collagen6.02976726
3MP0005275_abnormal_skin_tensile5.53509614
4MP0002837_dystrophic_cardiac_calcinosis5.20403852
5MP0000751_myopathy4.34310540
6MP0005503_abnormal_tendon_morphology4.18702113
7MP0004084_abnormal_cardiac_muscle3.11831321
8MP0001958_emphysema2.81932252
9MP0003646_muscle_fatigue2.78480866
10MP0004036_abnormal_muscle_relaxation2.70737878
11MP0000749_muscle_degeneration2.57233841
12MP0000750_abnormal_muscle_regeneration2.39919306
13MP0003279_aneurysm2.39728228
14MP0001986_abnormal_taste_sensitivity2.36400090
15MP0005330_cardiomyopathy2.31773405
16MP0004215_abnormal_myocardial_fiber2.30301498
17MP0003705_abnormal_hypodermis_morpholog2.27818820
18MP0010368_abnormal_lymphatic_system2.23067188
19MP0004272_abnormal_basement_membrane2.20160128
20MP0005423_abnormal_somatic_nervous2.12358052
21MP0004087_abnormal_muscle_fiber2.01296155
22MP0005620_abnormal_muscle_contractility1.92904941
23MP0009384_cardiac_valve_regurgitation1.92434900
24MP0002108_abnormal_muscle_morphology1.91341839
25MP0004130_abnormal_muscle_cell1.90479003
26MP0002106_abnormal_muscle_physiology1.87405478
27MP0000343_altered_response_to1.78280733
28MP0002972_abnormal_cardiac_muscle1.76010957
29MP0005369_muscle_phenotype1.74338701
30MP0003828_pulmonary_edema1.72133437
31MP0003566_abnormal_cell_adhesion1.72004622
32MP0002060_abnormal_skin_morphology1.70255559
33MP0001544_abnormal_cardiovascular_syste1.69975760
34MP0005385_cardiovascular_system_phenoty1.69975760
35MP0005670_abnormal_white_adipose1.60435300
36MP0000759_abnormal_skeletal_muscle1.57664787
37MP0004484_altered_response_of1.56697218
38MP0004145_abnormal_muscle_electrophysio1.54160244
39MP0001879_abnormal_lymphatic_vessel1.54042492
40MP0008775_abnormal_heart_ventricle1.51980202
41MP0000747_muscle_weakness1.49814618
42MP0005666_abnormal_adipose_tissue1.48873543
43MP0010630_abnormal_cardiac_muscle1.46591467
44MP0004185_abnormal_adipocyte_glucose1.46173181
45MP0003724_increased_susceptibility_to1.43729050
46MP0010386_abnormal_urinary_bladder1.43402991
47MP0006138_congestive_heart_failure1.41894655
48MP0002933_joint_inflammation1.34736939
49MP0001542_abnormal_bone_strength1.32852749
50MP0005253_abnormal_eye_physiology1.29627628
51MP0004510_myositis1.21402179
52MP0002269_muscular_atrophy1.19936327
53MP0005375_adipose_tissue_phenotype1.19193944
54MP0000767_abnormal_smooth_muscle1.19137231
55MP0009780_abnormal_chondrocyte_physiolo1.18382614
56MP0003137_abnormal_impulse_conducting1.15084478
57MP0000516_abnormal_urinary_system1.14257263
58MP0005367_renal/urinary_system_phenotyp1.14257263
59MP0005551_abnormal_eye_electrophysiolog1.13717926
60MP0004019_abnormal_vitamin_homeostasis1.10606861
61MP0004085_abnormal_heartbeat1.07859734
62MP0005508_abnormal_skeleton_morphology1.05830758
63MP0001533_abnormal_skeleton_physiology1.02239598
64MP0002166_altered_tumor_susceptibility1.01787590
65MP0003950_abnormal_plasma_membrane1.01060779
66MP0005165_increased_susceptibility_to0.98544348
67MP0000230_abnormal_systemic_arterial0.97298530
68MP0002295_abnormal_pulmonary_circulatio0.94508491
69MP0002796_impaired_skin_barrier0.94396077
70MP0000579_abnormal_nail_morphology0.94000437
71MP0000013_abnormal_adipose_tissue0.93850605
72MP0005623_abnormal_meninges_morphology0.93090315
73MP0005595_abnormal_vascular_smooth0.92620727
74MP0005390_skeleton_phenotype0.92570505
75MP0005257_abnormal_intraocular_pressure0.91403924
76MP0006054_spinal_hemorrhage0.91072541
77MP0003303_peritoneal_inflammation0.90802472
78MP0000733_abnormal_muscle_development0.90137613
79MP0003045_fibrosis0.89999155
80MP0002128_abnormal_blood_circulation0.84644480
81MP0002127_abnormal_cardiovascular_syste0.83512815
82MP0003300_gastrointestinal_ulcer0.81409426
83MP0003091_abnormal_cell_migration0.80953101
84MP0003191_abnormal_cellular_cholesterol0.78311420
85MP0005409_darkened_coat_color0.78147430
86MP0003436_decreased_susceptibility_to0.78132766
87MP0004134_abnormal_chest_morphology0.77744045
88MP0005388_respiratory_system_phenotype0.76410064
89MP0002133_abnormal_respiratory_system0.76410064
90MP0004858_abnormal_nervous_system0.76010979
91MP0002006_tumorigenesis0.75248140
92MP0000266_abnormal_heart_morphology0.74947449
93MP0005023_abnormal_wound_healing0.73743004
94MP0003221_abnormal_cardiomyocyte_apopto0.73202234
95MP0002971_abnormal_brown_adipose0.72286109
96MP0000003_abnormal_adipose_tissue0.71225057
97MP0002138_abnormal_hepatobiliary_system0.70644886
98MP0003690_abnormal_glial_cell0.69166788
99MP0004381_abnormal_hair_follicle0.68115952
100MP0001614_abnormal_blood_vessel0.67492238
101MP0000249_abnormal_blood_vessel0.67084902
102MP0000163_abnormal_cartilage_morphology0.66121531
103MP0001243_abnormal_dermal_layer0.65844019
104MP0006072_abnormal_retinal_apoptosis0.65576973
105MP0009379_abnormal_foot_pigmentation0.65083736
106MP0000534_abnormal_ureter_morphology0.65065547
107MP0009278_abnormal_bone_marrow0.65045605
108MP0001851_eye_inflammation0.65007834
109MP0003448_altered_tumor_morphology0.62880586
110MP0009115_abnormal_fat_cell0.62563858
111MP0002998_abnormal_bone_remodeling0.62180393
112MP0004233_abnormal_muscle_weight0.62169024
113MP0009250_abnormal_appendicular_skeleto0.61735599
114MP0003075_altered_response_to0.61197322
115MP0001299_abnormal_eye_distance/0.60397859
116MP0001661_extended_life_span0.60265708
117MP0002282_abnormal_trachea_morphology0.58994061
118MP0008260_abnormal_autophagy0.58283480
119MP0010771_integument_phenotype0.57652106
120MP0005164_abnormal_response_to0.56427722
121MP0001756_abnormal_urination0.56346927
122MP0005167_abnormal_blood-brain_barrier0.56166116
123MP0003941_abnormal_skin_development0.55619079
124MP0003567_abnormal_fetal_cardiomyocyte0.55597419
125MP0002896_abnormal_bone_mineralization0.55509362
126MP0005171_absent_coat_pigmentation0.54873439
127MP0000465_gastrointestinal_hemorrhage0.53234070
128MP0002925_abnormal_cardiovascular_devel0.52908135
129MP0002115_abnormal_skeleton_extremities0.47327595

Predicted human phenotypes

RankGene SetZ-score
1Muscle fiber splitting (HP:0003555)6.30121901
2Increased connective tissue (HP:0009025)6.10993514
3Congenital stationary night blindness (HP:0007642)5.63729092
4Type 1 muscle fiber predominance (HP:0003803)5.27334739
5Broad metatarsal (HP:0001783)5.03813541
6Sudden death (HP:0001699)4.86153588
7Ventricular tachycardia (HP:0004756)4.72087617
8Protrusio acetabuli (HP:0003179)4.36740304
9Exercise-induced myalgia (HP:0003738)4.35504696
10Right ventricular cardiomyopathy (HP:0011663)4.32411498
11Calf muscle hypertrophy (HP:0008981)4.19597714
12Ankle contracture (HP:0006466)4.17240821
13Exercise-induced muscle cramps (HP:0003710)4.16116182
14Round ear (HP:0100830)4.14923236
15Hyporeflexia of lower limbs (HP:0002600)4.14629616
16Muscle hypertrophy of the lower extremities (HP:0008968)3.97218732
17Decreased electroretinogram (ERG) amplitude (HP:0000654)3.86764403
18Premature rupture of membranes (HP:0001788)3.84150673
19Increased variability in muscle fiber diameter (HP:0003557)3.83440712
20Lipoatrophy (HP:0100578)3.81216426
21Vascular tortuosity (HP:0004948)3.78995606
22Wrist flexion contracture (HP:0001239)3.73218504
23Aortic dissection (HP:0002647)3.70263020
24Abnormality of the calf musculature (HP:0001430)3.69721440
25Abnormality of skeletal muscle fiber size (HP:0012084)3.66462168
26Atrial fibrillation (HP:0005110)3.47388644
27Cerebral aneurysm (HP:0004944)3.43051144
28Spinal rigidity (HP:0003306)3.32318784
29Pulmonary artery stenosis (HP:0004415)3.31704999
30Aortic aneurysm (HP:0004942)3.27002245
31Choroideremia (HP:0001139)3.25193178
32Difficulty running (HP:0009046)3.22818303
33Arterial tortuosity (HP:0005116)3.19045311
34Joint stiffness (HP:0001387)3.19021626
35Overgrowth (HP:0001548)3.18608049
36Primary atrial arrhythmia (HP:0001692)3.17809817
37EMG: myopathic abnormalities (HP:0003458)3.17692916
38Follicular hyperkeratosis (HP:0007502)3.17190772
39Asymmetric septal hypertrophy (HP:0001670)3.12342442
40Slender build (HP:0001533)3.11368462
41Supraventricular arrhythmia (HP:0005115)3.02303402
42Supraventricular tachycardia (HP:0004755)3.02087521
43Muscle fiber inclusion bodies (HP:0100299)3.00714798
44Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)2.93942960
45Myoglobinuria (HP:0002913)2.93151768
46Shallow orbits (HP:0000586)2.90381989
47Mildly elevated creatine phosphokinase (HP:0008180)2.85391486
48Abnormality of the left ventricular outflow tract (HP:0011103)2.84237488
49Subaortic stenosis (HP:0001682)2.84237488
50Genu recurvatum (HP:0002816)2.83414943
51Systemic lupus erythematosus (HP:0002725)2.81541978
52Vertebral compression fractures (HP:0002953)2.78346625
53Dilated cardiomyopathy (HP:0001644)2.77127363
54Soft skin (HP:0000977)2.75933271
55Scotoma (HP:0000575)2.74441871
56Myotonia (HP:0002486)2.68748452
57Distal lower limb muscle weakness (HP:0009053)2.63687176
58Abnormality of complement system (HP:0005339)2.59759920
59Aortic regurgitation (HP:0001659)2.59151409
60Nemaline bodies (HP:0003798)2.54097382
61Aortic valve stenosis (HP:0001650)2.53408044
62Facial diplegia (HP:0001349)2.50785279
63Ectopia lentis (HP:0001083)2.48944937
64Mesangial abnormality (HP:0001966)2.47486286
65Complement deficiency (HP:0004431)2.47052541
66Mitral regurgitation (HP:0001653)2.42549987
67Increased IgE level (HP:0003212)2.38140057
68Thin bony cortex (HP:0002753)2.37285723
69Testicular atrophy (HP:0000029)2.33497088
70Segmental peripheral demyelination/remyelination (HP:0003481)2.33165999
71Peritonitis (HP:0002586)2.33019374
72Neck muscle weakness (HP:0000467)2.31198127
73Fragile skin (HP:0001030)2.30481948
74Spondylolisthesis (HP:0003302)2.30054085
75Striae distensae (HP:0001065)2.30033395
76Bladder diverticulum (HP:0000015)2.29149748
77Emphysema (HP:0002097)2.28883418
78Neonatal short-limb short stature (HP:0008921)2.28695320
79Ulnar deviation of the wrist (HP:0003049)2.28301838
80Bundle branch block (HP:0011710)2.27251597
81Syncope (HP:0001279)2.26057663
82Eczematoid dermatitis (HP:0000976)2.25249873
83Ovoid vertebral bodies (HP:0003300)2.24242073
84Difficulty climbing stairs (HP:0003551)2.23587898
85Spontaneous hematomas (HP:0007420)2.19503421
86Ulnar claw (HP:0001178)2.18187949
87Atrophic scars (HP:0001075)2.17448380
88Biconcave vertebral bodies (HP:0004586)2.16283721
89Osteolytic defects of the phalanges of the hand (HP:0009771)2.15126125
90Osteolytic defects of the hand bones (HP:0009699)2.15126125
91Mitral valve prolapse (HP:0001634)2.13671064
92Cervical subluxation (HP:0003308)2.13267020
93Distal arthrogryposis (HP:0005684)2.13081941
94Aneurysm (HP:0002617)2.09924800
95Broad ribs (HP:0000885)2.09770863
96Increased corneal curvature (HP:0100692)2.09217320
97Keratoconus (HP:0000563)2.09217320
98Obstructive sleep apnea (HP:0002870)2.08668911
99Palpitations (HP:0001962)2.08430707
100Prolonged QT interval (HP:0001657)2.08031218
101Mitral stenosis (HP:0001718)2.07576247
102Rhabdomyolysis (HP:0003201)2.06872291
103Ventricular arrhythmia (HP:0004308)2.05378078
104Corneal dystrophy (HP:0001131)2.05052745
105Duplicated collecting system (HP:0000081)2.04423940
106Foot dorsiflexor weakness (HP:0009027)2.03694220
107Blue sclerae (HP:0000592)2.03511915
108Scapular winging (HP:0003691)2.02544402
109Muscle stiffness (HP:0003552)2.01772262
110Distal lower limb amyotrophy (HP:0008944)2.01558424
111Dilatation of the ascending aorta (HP:0005111)2.00777560
112Flat cornea (HP:0007720)1.98906886
113Proximal amyotrophy (HP:0007126)1.97862129
114Joint laxity (HP:0001388)1.96668255
115Abnormal atrioventricular conduction (HP:0005150)1.95933695
116Conjunctival hamartoma (HP:0100780)1.95632066
117Muscular dystrophy (HP:0003560)1.94771650
118Bony spicule pigmentary retinopathy (HP:0007737)1.94291703
119Palmoplantar keratoderma (HP:0000982)1.93673779
120Oligomenorrhea (HP:0000876)1.93136974
121Heart block (HP:0012722)1.92596402
122Abnormality of the foot musculature (HP:0001436)1.91408931
123Gingivitis (HP:0000230)1.89482974
124Venous abnormality (HP:0002624)1.88229129
125Short hallux (HP:0010109)1.86622918
126Hip contracture (HP:0003273)1.86385486
127Atrioventricular block (HP:0001678)1.85477010
128Glomerulonephritis (HP:0000099)1.85443757
129Rectal prolapse (HP:0002035)1.85306196
130Wormian bones (HP:0002645)1.85179125
131Hypoplasia of the iris (HP:0007676)1.84597993
132Attenuation of retinal blood vessels (HP:0007843)1.84245036
133Pigmentary retinal degeneration (HP:0001146)1.84123442
134Hematochezia (HP:0002573)1.83115648
135Venous insufficiency (HP:0005293)1.81771698
136Hyperextensible skin (HP:0000974)1.81149321
137Generalized amyotrophy (HP:0003700)1.79673213
138Nephritis (HP:0000123)1.79004160
139Polycythemia (HP:0001901)1.78130361
140Abnormality of the anterior chamber (HP:0000593)1.77948351
141Camptodactyly of toe (HP:0001836)1.77433142
142Acanthosis nigricans (HP:0000956)1.77275732
143Alopecia of scalp (HP:0002293)1.77179471
144Mild short stature (HP:0003502)1.73465850

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TTN6.53840414
2GRK14.24979677
3MYLK3.51585096
4TIE13.47032869
5TRIB33.28093740
6OBSCN3.15090592
7DMPK3.06104956
8PHKG13.03811790
9PHKG23.03811790
10TGFBR22.84106645
11EPHB12.42967018
12ERN12.20293960
13MST1R1.87230556
14PKN21.84891709
15LMTK21.83187177
16RIPK11.82351643
17EPHB21.75328941
18PRPF4B1.60686994
19MAPK71.57554861
20TESK11.56595999
21BLK1.55262013
22MAP2K31.48226957
23PIK3CA1.44012290
24TRPM71.40813385
25CAMK1D1.35424222
26PDK41.34104232
27PDK31.34104232
28PIK3CG1.32936848
29PDGFRA1.28846366
30WNK41.19519694
31EPHA31.15738034
32BCKDK1.15690331
33CSK1.14649795
34INSRR1.12281310
35KDR1.09814044
36MARK21.09193553
37IRAK41.07661002
38CAMK1G1.06501372
39SIK11.05127810
40PRKD11.02983804
41EEF2K1.02511404
42PDK21.02333686
43MAP3K30.98083260
44MAPKAPK30.95989518
45GRK50.94807374
46MAP3K70.94672968
47FER0.94230674
48STK380.92660361
49ILK0.91339495
50CAMK10.90715642
51DDR20.86862582
52PINK10.84097124
53PTK60.83864618
54ROCK10.82281335
55ABL20.81943626
56PRKAA20.80966270
57LATS20.78795424
58ROCK20.77240253
59NLK0.76594784
60MET0.76408588
61MAPK120.75924534
62GRK70.75115794
63IRAK30.74795072
64MOS0.72550850
65PRKCH0.71661543
66HIPK20.69949862
67PTK2B0.69941573
68MAP3K60.69364086
69STK240.68527576
70ADRBK10.68517282
71SGK2230.66943042
72SGK4940.66943042
73MAPK150.66642177
74PKN10.64398673
75LIMK10.62661158
76RPS6KC10.62419823
77RPS6KL10.62419823
78SGK30.62346434
79MAP3K130.61562955
80JAK10.58930707
81STK390.57293083
82RPS6KA60.56200610
83SGK20.55958992
84ZAP700.55380875
85NME10.55124778
86RPS6KA20.54132911
87ICK0.53731719
88JAK30.53664082
89KIT0.53572011
90KSR20.53448145
91CAMK2D0.53108240
92NEK90.52866661
93HCK0.52793673
94ZAK0.52615287
95MAP2K10.52009247
96MAP3K10.51739517
97ARAF0.50683930
98FES0.49690855
99PTK20.48509009
100BMX0.48373193
101CDC42BPA0.48119272
102PAK20.47686734
103FGFR40.47641790
104PRKD30.46552181
105PAK40.46387892
106CAMK2G0.46326647
107MARK10.45663357
108RET0.45086201
109PRKCE0.44836417
110MAPKAPK20.44247864
111PDGFRB0.43567776
112DAPK30.43445040
113FGR0.43207623
114MAP4K10.43042905
115JAK20.43029943
116TEC0.42614587
117AKT30.42407867
118IKBKE0.41670543
119MTOR0.40949002
120LRRK20.40791825
121PDPK10.39825531
122DYRK1B0.39748407
123LATS10.39671316
124PRKD20.39474931
125NTRK10.39465175
126WNK10.39414371
127GSK3A0.38166057
128MUSK0.37872198
129FGFR30.37289263
130PAK30.36467024
131TYK20.36254240
132TBK10.35788760
133PRKAA10.35756525
134IRAK10.32939436
135MAPK40.32628889
136TGFBR10.31902924
137CAMK40.31562318
138PRKACB0.30774852
139PRKG10.27061783

Predicted pathways (KEGG)

RankGene SetZ-score
1Phototransduction_Homo sapiens_hsa047444.99235399
2Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054103.56502024
3Dilated cardiomyopathy_Homo sapiens_hsa054143.41714721
4ECM-receptor interaction_Homo sapiens_hsa045123.26250337
5Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054122.70915324
6Citrate cycle (TCA cycle)_Homo sapiens_hsa000202.63892271
7Focal adhesion_Homo sapiens_hsa045102.30925378
8Staphylococcus aureus infection_Homo sapiens_hsa051502.14581728
9Cardiac muscle contraction_Homo sapiens_hsa042602.02106904
10Viral myocarditis_Homo sapiens_hsa054162.00542568
11Amoebiasis_Homo sapiens_hsa051461.89924309
12Protein digestion and absorption_Homo sapiens_hsa049741.69795402
13Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.64209800
14Other glycan degradation_Homo sapiens_hsa005111.62849249
15Malaria_Homo sapiens_hsa051441.55517254
16AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.54365076
172-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.49583005
18Propanoate metabolism_Homo sapiens_hsa006401.44220586
19Leukocyte transendothelial migration_Homo sapiens_hsa046701.37668056
20Insulin resistance_Homo sapiens_hsa049311.36375819
21Vascular smooth muscle contraction_Homo sapiens_hsa042701.30427504
22Fatty acid degradation_Homo sapiens_hsa000711.28677089
23Pertussis_Homo sapiens_hsa051331.24854843
24Leishmaniasis_Homo sapiens_hsa051401.21577040
25Adipocytokine signaling pathway_Homo sapiens_hsa049201.20258505
26Glycosaminoglycan degradation_Homo sapiens_hsa005311.18968535
27Platelet activation_Homo sapiens_hsa046111.18486904
28cGMP-PKG signaling pathway_Homo sapiens_hsa040221.16906906
29Toxoplasmosis_Homo sapiens_hsa051451.15701048
30Regulation of actin cytoskeleton_Homo sapiens_hsa048101.11404342
31Phospholipase D signaling pathway_Homo sapiens_hsa040721.10056018
32Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.07812731
33Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.07556713
34Proteoglycans in cancer_Homo sapiens_hsa052051.05828625
35Fatty acid metabolism_Homo sapiens_hsa012121.04506198
36Osteoclast differentiation_Homo sapiens_hsa043801.03975340
37alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.03822838
38Ovarian steroidogenesis_Homo sapiens_hsa049131.03576540
39Small cell lung cancer_Homo sapiens_hsa052221.03086303
40Adherens junction_Homo sapiens_hsa045201.00664610
41Arachidonic acid metabolism_Homo sapiens_hsa005901.00284882
42PPAR signaling pathway_Homo sapiens_hsa033201.00023067
43Starch and sucrose metabolism_Homo sapiens_hsa005000.99578341
44Complement and coagulation cascades_Homo sapiens_hsa046100.95462207
45Insulin signaling pathway_Homo sapiens_hsa049100.94125115
46Ras signaling pathway_Homo sapiens_hsa040140.93886474
47Aldosterone synthesis and secretion_Homo sapiens_hsa049250.93071527
48Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.90067529
49PI3K-Akt signaling pathway_Homo sapiens_hsa041510.89823525
50Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.89276624
51Renin secretion_Homo sapiens_hsa049240.86919318
52Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.86754579
53Alzheimers disease_Homo sapiens_hsa050100.86373735
54Caffeine metabolism_Homo sapiens_hsa002320.82453484
55Histidine metabolism_Homo sapiens_hsa003400.81973552
56Melanogenesis_Homo sapiens_hsa049160.80117422
57Glioma_Homo sapiens_hsa052140.78677284
58HIF-1 signaling pathway_Homo sapiens_hsa040660.77897324
59Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.77346448
60Calcium signaling pathway_Homo sapiens_hsa040200.75668806
61Parkinsons disease_Homo sapiens_hsa050120.74795014
62AMPK signaling pathway_Homo sapiens_hsa041520.72093067
63Glucagon signaling pathway_Homo sapiens_hsa049220.71401668
64Carbon metabolism_Homo sapiens_hsa012000.70146324
65Oxytocin signaling pathway_Homo sapiens_hsa049210.69844714
66Melanoma_Homo sapiens_hsa052180.69569019
67Bladder cancer_Homo sapiens_hsa052190.69220810
68Notch signaling pathway_Homo sapiens_hsa043300.69167961
69Salmonella infection_Homo sapiens_hsa051320.67953697
70Endocytosis_Homo sapiens_hsa041440.67255260
71VEGF signaling pathway_Homo sapiens_hsa043700.66194036
72Circadian entrainment_Homo sapiens_hsa047130.66134723
73Jak-STAT signaling pathway_Homo sapiens_hsa046300.66041278
74Fatty acid biosynthesis_Homo sapiens_hsa000610.65993757
75Phagosome_Homo sapiens_hsa041450.65538670
76mTOR signaling pathway_Homo sapiens_hsa041500.65175672
77FoxO signaling pathway_Homo sapiens_hsa040680.63529700
78Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.63092285
79Tuberculosis_Homo sapiens_hsa051520.62974703
80Acute myeloid leukemia_Homo sapiens_hsa052210.59650835
81cAMP signaling pathway_Homo sapiens_hsa040240.59300534
82Rap1 signaling pathway_Homo sapiens_hsa040150.59049274
83Chronic myeloid leukemia_Homo sapiens_hsa052200.58874269
84Neurotrophin signaling pathway_Homo sapiens_hsa047220.58628723
85Gap junction_Homo sapiens_hsa045400.58387970
86Oxidative phosphorylation_Homo sapiens_hsa001900.58206129
87Pathways in cancer_Homo sapiens_hsa052000.58129326
88Thyroid hormone signaling pathway_Homo sapiens_hsa049190.57956209
89Long-term potentiation_Homo sapiens_hsa047200.57890477
90Fatty acid elongation_Homo sapiens_hsa000620.56634906
91Tight junction_Homo sapiens_hsa045300.56614500
92Choline metabolism in cancer_Homo sapiens_hsa052310.56108591
93Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.55903212
94Lysosome_Homo sapiens_hsa041420.55669478
95Type II diabetes mellitus_Homo sapiens_hsa049300.54946338
96Linoleic acid metabolism_Homo sapiens_hsa005910.54590791
97Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.54564553
98beta-Alanine metabolism_Homo sapiens_hsa004100.54299669
99Chemokine signaling pathway_Homo sapiens_hsa040620.52532629
100Prostate cancer_Homo sapiens_hsa052150.51938106
101Renal cell carcinoma_Homo sapiens_hsa052110.51843745
102Dorso-ventral axis formation_Homo sapiens_hsa043200.51787051
103Lysine degradation_Homo sapiens_hsa003100.51394357
104Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.51264251
105Central carbon metabolism in cancer_Homo sapiens_hsa052300.51091211
106Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.50887931
107Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.50465007
108Gastric acid secretion_Homo sapiens_hsa049710.49668479
109Pancreatic cancer_Homo sapiens_hsa052120.49304641
110Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.49282876
111Circadian rhythm_Homo sapiens_hsa047100.49223052
112Salivary secretion_Homo sapiens_hsa049700.49064448
113Hedgehog signaling pathway_Homo sapiens_hsa043400.47433180
114Estrogen signaling pathway_Homo sapiens_hsa049150.46526846
115Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.46082699
116Tyrosine metabolism_Homo sapiens_hsa003500.45489640
117Glycerophospholipid metabolism_Homo sapiens_hsa005640.45045465
118Prion diseases_Homo sapiens_hsa050200.44126446
119Renin-angiotensin system_Homo sapiens_hsa046140.44102628
120Long-term depression_Homo sapiens_hsa047300.44039493
121Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.44017098
122Axon guidance_Homo sapiens_hsa043600.43774926
123Longevity regulating pathway - mammal_Homo sapiens_hsa042110.42878127
124MAPK signaling pathway_Homo sapiens_hsa040100.42623381
125Phosphatidylinositol signaling system_Homo sapiens_hsa040700.42600647
126ABC transporters_Homo sapiens_hsa020100.41372439
127GnRH signaling pathway_Homo sapiens_hsa049120.40971345
128TNF signaling pathway_Homo sapiens_hsa046680.40528629
129Toll-like receptor signaling pathway_Homo sapiens_hsa046200.40507684
130TGF-beta signaling pathway_Homo sapiens_hsa043500.39827026
131Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.39436689
132Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.38564643
133Phenylalanine metabolism_Homo sapiens_hsa003600.38274217
134Hematopoietic cell lineage_Homo sapiens_hsa046400.38128334

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »