PIFO

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1motile cilium assembly (GO:0044458)9.98767282
2ventricular system development (GO:0021591)9.90359266
3GTP biosynthetic process (GO:0006183)9.64009264
4nucleoside diphosphate phosphorylation (GO:0006165)8.82744927
5UTP biosynthetic process (GO:0006228)8.57402905
6intraciliary transport (GO:0042073)8.44709546
7left/right axis specification (GO:0070986)8.05911229
8UTP metabolic process (GO:0046051)7.89658053
9regulation of cilium movement (GO:0003352)7.14034892
10microtubule bundle formation (GO:0001578)6.80908971
11guanosine-containing compound biosynthetic process (GO:1901070)6.61189062
12cilium organization (GO:0044782)6.54374425
13cilium morphogenesis (GO:0060271)6.52163270
14CTP metabolic process (GO:0046036)6.43151354
15CTP biosynthetic process (GO:0006241)6.43151354
16cilium assembly (GO:0042384)6.17882250
17primary alcohol catabolic process (GO:0034310)5.95576183
18pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)5.86363884
19sperm motility (GO:0030317)5.80953975
20microtubule severing (GO:0051013)5.66551769
21vitamin transmembrane transport (GO:0035461)5.62150150
22pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208)5.52495184
23protein localization to cilium (GO:0061512)5.47061879
24sensory perception of smell (GO:0007608)5.36980541
25cellular component assembly involved in morphogenesis (GO:0010927)5.28712988
26ethanol metabolic process (GO:0006067)5.04425871
27microtubule-based movement (GO:0007018)4.99175945
28protein polyglutamylation (GO:0018095)4.92827793
29fusion of sperm to egg plasma membrane (GO:0007342)4.87113491
30pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)4.86353695
31nucleotide phosphorylation (GO:0046939)4.82920541
32diterpenoid biosynthetic process (GO:0016102)4.76313913
33acrosome reaction (GO:0007340)4.62359919
34lung epithelium development (GO:0060428)4.50775932
35spermatid development (GO:0007286)4.37585899
36pyrimidine nucleoside triphosphate metabolic process (GO:0009147)4.36377436
37negative regulation of inclusion body assembly (GO:0090084)4.35899283
38pyrimidine-containing compound transmembrane transport (GO:0072531)4.34209751
39nucleoside diphosphate metabolic process (GO:0009132)4.33332078
40cell projection assembly (GO:0030031)4.28049547
41sperm-egg recognition (GO:0035036)4.21633962
42response to xenobiotic stimulus (GO:0009410)4.17821176
43negative regulation of T cell differentiation in thymus (GO:0033085)4.07408739
44single fertilization (GO:0007338)4.06565390
45multicellular organism reproduction (GO:0032504)4.06145446
46regulation of microtubule-based movement (GO:0060632)4.04531856
47cell wall macromolecule metabolic process (GO:0044036)4.04287837
48cell wall macromolecule catabolic process (GO:0016998)4.04287837
49centriole assembly (GO:0098534)4.03511874
50binding of sperm to zona pellucida (GO:0007339)4.00857693
51establishment of apical/basal cell polarity (GO:0035089)4.00755874
52tolerance induction (GO:0002507)3.98908468
53glomerular epithelial cell development (GO:0072310)3.98565538
54lateral ventricle development (GO:0021670)3.94978631
55acrosome assembly (GO:0001675)3.91279162
56ethanol oxidation (GO:0006069)3.81708432
57C21-steroid hormone biosynthetic process (GO:0006700)3.79799790
58negative regulation of B cell mediated immunity (GO:0002713)3.74963042
59negative regulation of immunoglobulin mediated immune response (GO:0002890)3.74963042
60regulation of interleukin-5 production (GO:0032674)3.74419492
61cell-cell recognition (GO:0009988)3.72167298
62pyrimidine ribonucleoside biosynthetic process (GO:0046132)3.70274051
63centriole replication (GO:0007099)3.63744467
64plasma membrane fusion (GO:0045026)3.63705225
65negative regulation of humoral immune response (GO:0002921)3.55834318
66regulation of inclusion body assembly (GO:0090083)3.55497888
67establishment of monopolar cell polarity (GO:0061162)3.52040495
68establishment or maintenance of monopolar cell polarity (GO:0061339)3.52040495
69pyrimidine ribonucleotide biosynthetic process (GO:0009220)3.50608121
70one-carbon compound transport (GO:0019755)3.49930930
71male meiosis I (GO:0007141)3.48843170
72purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.48120276
73smoothened signaling pathway (GO:0007224)3.45912203
74retinoic acid metabolic process (GO:0042573)3.44812178
75glutathione derivative metabolic process (GO:1901685)3.41819361
76glutathione derivative biosynthetic process (GO:1901687)3.41819361
77ADP metabolic process (GO:0046031)3.41495014
78establishment of planar polarity (GO:0001736)3.40911962
79establishment of tissue polarity (GO:0007164)3.40911962
80terpenoid biosynthetic process (GO:0016114)3.40879632
81cytoplasmic microtubule organization (GO:0031122)3.38475369
82purine nucleoside triphosphate biosynthetic process (GO:0009145)3.36694114
83determination of left/right symmetry (GO:0007368)3.36155259
84fertilization (GO:0009566)3.35879425
85left/right pattern formation (GO:0060972)3.34255355
86progesterone metabolic process (GO:0042448)3.32145794
87sensory perception of chemical stimulus (GO:0007606)3.30772758
88microtubule depolymerization (GO:0007019)3.26077932
89lateral sprouting from an epithelium (GO:0060601)3.23626412
90determination of bilateral symmetry (GO:0009855)3.22842970
91reproduction (GO:0000003)3.22386870
92spermatogenesis (GO:0007283)3.20206616
93pyrimidine ribonucleotide metabolic process (GO:0009218)3.19491339
94positive regulation of smoothened signaling pathway (GO:0045880)3.18509788
95male gamete generation (GO:0048232)3.18239151
96regulation of interleukin-13 production (GO:0032656)3.17711618
97specification of symmetry (GO:0009799)3.15702394
98negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)3.15556839
99positive regulation of tolerance induction (GO:0002645)3.11567570
100male meiosis (GO:0007140)3.11259316
101regulation of pigment cell differentiation (GO:0050932)3.11155227
102phospholipase C-activating dopamine receptor signaling pathway (GO:0060158)3.08945740
103regulation of germinal center formation (GO:0002634)3.08316946
104nonmotile primary cilium assembly (GO:0035058)3.05650999
105microtubule polymerization or depolymerization (GO:0031109)3.05352791
106retinol metabolic process (GO:0042572)3.00813036
107brain morphogenesis (GO:0048854)2.98557612
108oxygen transport (GO:0015671)2.98394623
109ribonucleoside triphosphate biosynthetic process (GO:0009201)2.96415560
110gamete generation (GO:0007276)2.96267495
111nucleoside triphosphate biosynthetic process (GO:0009142)2.96101867
112exogenous drug catabolic process (GO:0042738)2.93306540
113primary alcohol metabolic process (GO:0034308)2.92486640
114apical protein localization (GO:0045176)2.91120576
115embryonic camera-type eye development (GO:0031076)2.89932605
116regulation of glucose import in response to insulin stimulus (GO:2001273)2.88594478
117synaptonemal complex organization (GO:0070193)2.88007542
118meiotic cell cycle (GO:0051321)2.86923644
119piRNA metabolic process (GO:0034587)2.82338739
120asymmetric protein localization (GO:0008105)2.81483187
121pyrimidine ribonucleoside metabolic process (GO:0046131)2.79161808
122carnitine metabolic process (GO:0009437)2.77685911
123spermatid nucleus differentiation (GO:0007289)2.77364819
124retinal rod cell development (GO:0046548)2.75519444
125aldehyde catabolic process (GO:0046185)2.72274851
126meiosis I (GO:0007127)2.70235349
127pyrimidine nucleotide biosynthetic process (GO:0006221)2.69914725
128microtubule-based process (GO:0007017)2.69723160
129regulation of macrophage chemotaxis (GO:0010758)2.67127820
130organelle assembly (GO:0070925)2.64894402
131regulation of autophagic vacuole assembly (GO:2000785)2.64067788
132hydrogen peroxide biosynthetic process (GO:0050665)2.61647648
133heart looping (GO:0001947)2.61214644
134multicellular organismal aging (GO:0010259)2.60522374
135O-glycan processing (GO:0016266)2.59477969
136gas transport (GO:0015669)2.57170116
137sperm capacitation (GO:0048240)2.53249911
138embryonic heart tube morphogenesis (GO:0003143)2.51590417
139keratinocyte development (GO:0003334)2.51269992
140regulation of smoothened signaling pathway (GO:0008589)2.46734073
141intra-S DNA damage checkpoint (GO:0031573)2.45240228
142eye photoreceptor cell differentiation (GO:0001754)2.44001070
143photoreceptor cell differentiation (GO:0046530)2.44001070
144positive regulation of cellular response to insulin stimulus (GO:1900078)2.41567042
145phosphatidylcholine biosynthetic process (GO:0006656)2.41028995
146regulation of collateral sprouting (GO:0048670)2.36550310
147photoreceptor cell maintenance (GO:0045494)2.36464877
148multicellular organismal water homeostasis (GO:0050891)2.33645348
149regulation of microtubule depolymerization (GO:0031114)2.30365246
150excretion (GO:0007588)2.30239672
151reactive oxygen species biosynthetic process (GO:1903409)2.29861284
152regulation of vacuole organization (GO:0044088)2.29172772
153hydrogen peroxide catabolic process (GO:0042744)2.22967415
154glutathione metabolic process (GO:0006749)2.22342269
155cilium movement (GO:0003341)16.8814074
156axonemal dynein complex assembly (GO:0070286)16.4049326
157cilium or flagellum-dependent cell motility (GO:0001539)13.5357805
158axoneme assembly (GO:0035082)13.2795707
159epithelial cilium movement (GO:0003351)12.7163289
160epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)10.1253886

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat5.00742121
2BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse4.57735370
3CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human3.82056981
4FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human2.96130286
5CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human2.86916261
6MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.77398079
7EZH2_22144423_ChIP-Seq_EOC_Human2.67724204
8RBPJ_22232070_ChIP-Seq_NCS_Mouse2.66938254
9TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.57654825
10GATA1_26923725_Chip-Seq_HPCs_Mouse2.22320629
11TRIM28_21343339_ChIP-Seq_HEK293_Human2.15435801
12PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.12605868
13TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.95857192
14RNF2_27304074_Chip-Seq_NSC_Mouse1.86991316
15GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.84182216
16FOXM1_26456572_ChIP-Seq_MCF-7_Human1.82203924
17SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.77734272
18ESR1_20079471_ChIP-ChIP_T-47D_Human1.75386017
19SMAD4_21799915_ChIP-Seq_A2780_Human1.71133343
20CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.66742212
21NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.64605202
22FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.64094448
23TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.63059660
24POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.63059660
25PCGF2_27294783_Chip-Seq_NPCs_Mouse1.60798616
26NR3C1_21868756_ChIP-Seq_MCF10A_Human1.59158118
27TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.56114197
28EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.56015961
29TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.55720274
30STAT1_20625510_ChIP-Seq_HELA_Human1.55365398
31ZFP57_27257070_Chip-Seq_ESCs_Mouse1.54977778
32CTBP2_25329375_ChIP-Seq_LNCAP_Human1.54146139
33CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.54102370
34CBX2_27304074_Chip-Seq_ESCs_Mouse1.53244612
35TAL1_26923725_Chip-Seq_HPCs_Mouse1.52953803
36PCGF2_27294783_Chip-Seq_ESCs_Mouse1.52294930
37SUZ12_27294783_Chip-Seq_NPCs_Mouse1.52282417
38TP63_23658742_ChIP-Seq_EP156T_Human1.52230150
39FLI1_27457419_Chip-Seq_LIVER_Mouse1.51838146
40TP53_18474530_ChIP-ChIP_U2OS_Human1.51640996
41ER_23166858_ChIP-Seq_MCF-7_Human1.47615433
42AR_21572438_ChIP-Seq_LNCaP_Human1.47447072
43CTBP1_25329375_ChIP-Seq_LNCAP_Human1.46504094
44WDR5_24793694_ChIP-Seq_LNCAP_Human1.46111307
45ZNF217_24962896_ChIP-Seq_MCF-7_Human1.45150165
46DROSHA_22980978_ChIP-Seq_HELA_Human1.45081005
47PHF8_20622853_ChIP-Seq_HELA_Human1.44844603
48P300_19829295_ChIP-Seq_ESCs_Human1.44608113
49RUNX1_27514584_Chip-Seq_MCF-7_Human1.43237918
50NFE2_27457419_Chip-Seq_LIVER_Mouse1.42914835
51SOX9_26525672_Chip-Seq_Limbbuds_Mouse1.42867806
52BCAT_22108803_ChIP-Seq_LS180_Human1.41756376
53LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.40605164
54ETV1_20927104_ChIP-Seq_GIST48_Human1.40551294
55IGF1R_20145208_ChIP-Seq_DFB_Human1.38435428
56EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.38198275
57CTNNB1_20460455_ChIP-Seq_HCT116_Human1.35944661
58TOP2B_26459242_ChIP-Seq_MCF-7_Human1.35592891
59EZH2_27294783_Chip-Seq_ESCs_Mouse1.35479859
60PIAS1_25552417_ChIP-Seq_VCAP_Human1.34005035
61ARNT_22903824_ChIP-Seq_MCF-7_Human1.33902031
62PCGF4_22325352_ChIP-Seq_293T-Rex_Human1.33369311
63SOX2_27498859_Chip-Seq_STOMACH_Mouse1.33252515
64CDX2_21074721_ChIP-Seq_CACO-2_Mouse1.32808931
65HNFA_21074721_ChIP-Seq_CACO-2_Human1.32761112
66SMC4_20622854_ChIP-Seq_HELA_Human1.30572699
67ESR1_21235772_ChIP-Seq_MCF-7_Human1.30539643
68CDX2_20551321_ChIP-Seq_CACO-2_Human1.29724443
69TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.29442274
70CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.28362507
71AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.28322583
72FOXA1_25552417_ChIP-Seq_VCAP_Human1.28236440
73MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.28039008
74LMO2_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.27828090
75BMI1_23680149_ChIP-Seq_NPCS_Mouse1.27465201
76CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.27309076
77NANOG_18555785_Chip-Seq_ESCs_Mouse1.27102638
78SMAD4_21741376_ChIP-Seq_EPCs_Human1.27010658
79FUS_26573619_Chip-Seq_HEK293_Human1.26220062
80SUZ12_27294783_Chip-Seq_ESCs_Mouse1.25473405
81P53_22387025_ChIP-Seq_ESCs_Mouse1.24519041
82LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse1.24325437
83TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.22548784
84PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.22186785
85TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.22120174
86E2F1_18555785_Chip-Seq_ESCs_Mouse1.21119641
87PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.20976505
88SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.20780701
89CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.20335274
90SOX2_22085726_ChIP-Seq_NPCs_Mouse1.19036411
91SMRT_27268052_Chip-Seq_Bcells_Human1.18284259
92TBL1_22424771_ChIP-Seq_293T_Human1.17986776
93SMAD3_21741376_ChIP-Seq_EPCs_Human1.16754621
94KLF5_25053715_ChIP-Seq_YYC3_Human1.16704670
95RAD21_21589869_ChIP-Seq_MESCs_Mouse1.15997901
96SOX9_24532713_ChIP-Seq_HFSC_Mouse1.15949486
97RBPJ_21746931_ChIP-Seq_IB4_Human1.15839071
98ZFX_18555785_Chip-Seq_ESCs_Mouse1.15464643
99ESR2_21235772_ChIP-Seq_MCF-7_Human1.15252320
100TCF4_22108803_ChIP-Seq_LS180_Human1.15161151
101TAF15_26573619_Chip-Seq_HEK293_Human1.15146921
102NFYA_21822215_ChIP-Seq_K562_Human1.14976577
103KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.14799465
104CMYC_18555785_Chip-Seq_ESCs_Mouse1.14150641
105OCT4_18555785_Chip-Seq_ESCs_Mouse1.13425511
106ERG_20517297_ChIP-Seq_VCAP_Human1.13256505
107EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.12924002
108STAT3_18555785_Chip-Seq_ESCs_Mouse1.12744314
109AHR_22903824_ChIP-Seq_MCF-7_Human1.12584537
110SOX2_20726797_ChIP-Seq_SW620_Human1.12103487
111SMAD_19615063_ChIP-ChIP_OVARY_Human1.11390186
112P300_18555785_Chip-Seq_ESCs_Mouse1.10649624
113SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.10444648
114IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.10120803
115CBP_20019798_ChIP-Seq_JUKART_Human1.10120803
116SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.10079749
117TDRD3_21172665_ChIP-Seq_MCF-7_Human1.09971980
118REST_21632747_ChIP-Seq_MESCs_Mouse1.09792220
119FLI1_21867929_ChIP-Seq_TH2_Mouse1.09118642
120SOX2_18555785_Chip-Seq_ESCs_Mouse1.08913416
121CBX2_22325352_ChIP-Seq_293T-Rex_Human1.08844271
122KAP1_22055183_ChIP-Seq_ESCs_Mouse1.08795645
123EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.08459567
124AUTS2_25519132_ChIP-Seq_293T-REX_Human1.08455927
125VDR_22108803_ChIP-Seq_LS180_Human1.08310854
126NFYB_21822215_ChIP-Seq_K562_Human1.08107638
127TP63_22573176_ChIP-Seq_HFKS_Human1.07981013
128SUZ12_18555785_Chip-Seq_ESCs_Mouse1.07272408
129GATA6_21074721_ChIP-Seq_CACO-2_Human1.06961544
130ELK4_26923725_Chip-Seq_MESODERM_Mouse1.06684914
131ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.06093598
132GATA6_21074721_ChIP-Seq_CACO-2_Mouse1.05783738
133EZH2_27294783_Chip-Seq_NPCs_Mouse1.05048562
134SMAD3_21741376_ChIP-Seq_HESCs_Human1.04499956
135CRX_20693478_ChIP-Seq_RETINA_Mouse1.03085611
136MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.03003360
137STAT3_23295773_ChIP-Seq_U87_Human1.02738030
138SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.02266467
139GF1_26923725_Chip-Seq_HPCs_Mouse1.01902444
140OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.01066986
141P53_21459846_ChIP-Seq_SAOS-2_Human1.00595980
142FOXA1_25329375_ChIP-Seq_VCAP_Human1.00118114
143FOXA1_27270436_Chip-Seq_PROSTATE_Human1.00118114
144AR_20517297_ChIP-Seq_VCAP_Human0.99518867
145POU3F2_20337985_ChIP-ChIP_501MEL_Human0.99020757
146ESRRB_18555785_Chip-Seq_ESCs_Mouse0.98990346
147GF1B_26923725_Chip-Seq_HPCs_Mouse0.98219058
148P63_26484246_Chip-Seq_KERATINOCYTES_Human0.95173454
149CBP_21632823_ChIP-Seq_H3396_Human0.94473419
150CDX2_22108803_ChIP-Seq_LS180_Human0.94372843
151FOXA1_26743006_Chip-Seq_LNCaP-abl_Human0.94207017
152RUNX2_22187159_ChIP-Seq_PCA_Human0.93477677
153STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse0.92572115
154GATA4_25053715_ChIP-Seq_YYC3_Human0.90880449
155SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.90709826
156CEBPB_22108803_ChIP-Seq_LS180_Human0.89806090
157TP63_17297297_ChIP-ChIP_HaCaT_Human0.89460018
158YY1_22570637_ChIP-Seq_MALME-3M_Human0.89171480
159GATA3_24758297_ChIP-Seq_MCF-7_Human0.88460226
160SOX2_21211035_ChIP-Seq_LN229_Human0.87733985
161SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.87261863

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001984_abnormal_olfaction7.13031520
2MP0003136_yellow_coat_color6.24936569
3MP0005410_abnormal_fertilization5.75845668
4MP0002653_abnormal_ependyma_morphology5.24851140
5MP0008004_abnormal_stomach_pH4.44628439
6MP0000566_synostosis3.96844694
7MP0002277_abnormal_respiratory_mucosa3.42750605
8MP0005623_abnormal_meninges_morphology3.26176900
9MP0002160_abnormal_reproductive_system3.19697951
10MP0005646_abnormal_pituitary_gland3.17559241
11MP0004043_abnormal_pH_regulation3.05190630
12MP0002928_abnormal_bile_duct2.71463122
13MP0003698_abnormal_male_reproductive2.65330060
14MP0004133_heterotaxia2.58243650
15MP0009780_abnormal_chondrocyte_physiolo2.51745821
16MP0003011_delayed_dark_adaptation2.38523193
17MP0001929_abnormal_gametogenesis2.25688263
18MP0008789_abnormal_olfactory_epithelium2.24935422
19MP0000383_abnormal_hair_follicle2.17100471
20MP0005394_taste/olfaction_phenotype2.06495626
21MP0005499_abnormal_olfactory_system2.06495626
22MP0001958_emphysema1.84719707
23MP0010678_abnormal_skin_adnexa1.73615975
24MP0005389_reproductive_system_phenotype1.66496585
25MP0002210_abnormal_sex_determination1.58023040
26MP0002282_abnormal_trachea_morphology1.57648567
27MP0002249_abnormal_larynx_morphology1.54003256
28MP0009379_abnormal_foot_pigmentation1.53008226
29MP0005647_abnormal_sex_gland1.52409006
30MP0004381_abnormal_hair_follicle1.46090833
31MP0002638_abnormal_pupillary_reflex1.41866922
32MP0005409_darkened_coat_color1.39345189
33MP0002161_abnormal_fertility/fecundity1.39110714
34MP0003186_abnormal_redox_activity1.35069352
35MP0000049_abnormal_middle_ear1.30792645
36MP0005551_abnormal_eye_electrophysiolog1.29450409
37MP0001346_abnormal_lacrimal_gland1.29276337
38MP0005248_abnormal_Harderian_gland1.28744684
39MP0001188_hyperpigmentation1.27046976
40MP0002132_abnormal_respiratory_system1.25427100
41MP0003942_abnormal_urinary_system1.23310168
42MP0001145_abnormal_male_reproductive1.22300899
43MP0003806_abnormal_nucleotide_metabolis1.18352658
44MP0000778_abnormal_nervous_system1.16915049
45MP0003283_abnormal_digestive_organ1.16312059
46MP0000653_abnormal_sex_gland1.15754660
47MP0003656_abnormal_erythrocyte_physiolo1.15721899
48MP0002876_abnormal_thyroid_physiology1.05486429
49MP0005388_respiratory_system_phenotype1.03580730
50MP0002133_abnormal_respiratory_system1.03580730
51MP0003937_abnormal_limbs/digits/tail_de1.03554615
52MP0005408_hypopigmentation1.02218231
53MP0009046_muscle_twitch1.00214774
54MP0001485_abnormal_pinna_reflex0.99865722
55MP0005377_hearing/vestibular/ear_phenot0.99379234
56MP0003878_abnormal_ear_physiology0.99379234
57MP0002557_abnormal_social/conspecific_i0.97772071
58MP0001324_abnormal_eye_pigmentation0.97695300
59MP0003880_abnormal_central_pattern0.97680710
60MP0005083_abnormal_biliary_tract0.97280417
61MP0001873_stomach_inflammation0.97122773
62MP0003634_abnormal_glial_cell0.96640970
63MP0004019_abnormal_vitamin_homeostasis0.95670270
64MP0008875_abnormal_xenobiotic_pharmacok0.94739382
65MP0001440_abnormal_grooming_behavior0.94374341
66MP0004782_abnormal_surfactant_physiolog0.94364191
67MP0005670_abnormal_white_adipose0.92806686
68MP0001177_atelectasis0.91224427
69MP0002734_abnormal_mechanical_nocicepti0.88750720
70MP0000631_abnormal_neuroendocrine_gland0.88466159
71MP0002168_other_aberrant_phenotype0.87601383
72MP0008877_abnormal_DNA_methylation0.87515422
73MP0003890_abnormal_embryonic-extraembry0.87464027
74MP0005395_other_phenotype0.85189183
75MP0005636_abnormal_mineral_homeostasis0.85188727
76MP0005503_abnormal_tendon_morphology0.84029657
77MP0002938_white_spotting0.83536986
78MP0005171_absent_coat_pigmentation0.81425094
79MP0005423_abnormal_somatic_nervous0.80567626
80MP0000678_abnormal_parathyroid_gland0.80371193
81MP0001851_eye_inflammation0.79309048
82MP0009250_abnormal_appendicular_skeleto0.78986916
83MP0002752_abnormal_somatic_nervous0.78333771
84MP0003943_abnormal_hepatobiliary_system0.77933432
85MP0001270_distended_abdomen0.77705345
86MP0005075_abnormal_melanosome_morpholog0.77508850
87MP0002735_abnormal_chemical_nociception0.76502172
88MP0005365_abnormal_bile_salt0.76227024
89MP0001501_abnormal_sleep_pattern0.75955444
90MP0000955_abnormal_spinal_cord0.75948430
91MP0000613_abnormal_salivary_gland0.74792075
92MP0001905_abnormal_dopamine_level0.74723739
93MP0002152_abnormal_brain_morphology0.74540291
94MP0001765_abnormal_ion_homeostasis0.74186801
95MP0002233_abnormal_nose_morphology0.73426108
96MP0006292_abnormal_olfactory_placode0.73269222
97MP0005253_abnormal_eye_physiology0.72592832
98MP0002822_catalepsy0.71372239
99MP0000428_abnormal_craniofacial_morphol0.70728111
100MP0002909_abnormal_adrenal_gland0.70623619
101MP0002272_abnormal_nervous_system0.70010067
102MP0000467_abnormal_esophagus_morphology0.69197075
103MP0003690_abnormal_glial_cell0.68775711
104MP0001963_abnormal_hearing_physiology0.68515634
105MP0002295_abnormal_pulmonary_circulatio0.68503324
106MP0003861_abnormal_nervous_system0.68333849
107MP0002184_abnormal_innervation0.65960304
108MP0002084_abnormal_developmental_patter0.65301194
109MP0002098_abnormal_vibrissa_morphology0.65144234
110MP0009384_cardiac_valve_regurgitation0.64821053
111MP0001299_abnormal_eye_distance/0.63976836
112MP0003938_abnormal_ear_development0.63754193
113MP0009703_decreased_birth_body0.63576691
114MP0001286_abnormal_eye_development0.63172593
115MP0005085_abnormal_gallbladder_physiolo0.62985385
116MP0002405_respiratory_system_inflammati0.62978910
117MP0003633_abnormal_nervous_system0.62765307
118MP0005508_abnormal_skeleton_morphology0.62037639
119MP0005165_increased_susceptibility_to0.61665482
120MP0002116_abnormal_craniofacial_bone0.61559142
121MP0000470_abnormal_stomach_morphology0.61526563
122MP0004883_abnormal_blood_vessel0.60642181
123MP0004858_abnormal_nervous_system0.60489942
124MP0002882_abnormal_neuron_morphology0.59416002
125MP0000026_abnormal_inner_ear0.58612617
126MP0005391_vision/eye_phenotype0.58319129
127MP0009765_abnormal_xenobiotic_induced0.58232232
128MP0005195_abnormal_posterior_eye0.56506178
129MP0001502_abnormal_circadian_rhythm0.56124023
130MP0001970_abnormal_pain_threshold0.56052646
131MP0001486_abnormal_startle_reflex0.55669556
132MP0002572_abnormal_emotion/affect_behav0.55096528
133MP0010030_abnormal_orbit_morphology0.54916841
134MP0009643_abnormal_urine_homeostasis0.54849514
135MP0008995_early_reproductive_senescence0.54445573
136MP0002109_abnormal_limb_morphology0.54206240
137MP0005220_abnormal_exocrine_pancreas0.54180796
138MP0002064_seizures0.54019148
139MP0001293_anophthalmia0.52302575
140MP0001944_abnormal_pancreas_morphology0.52127552
141MP0002092_abnormal_eye_morphology0.52098401
142MP0005164_abnormal_response_to0.51551707
143MP0003879_abnormal_hair_cell0.51549620
144MP0001849_ear_inflammation0.49281271
145MP0002136_abnormal_kidney_physiology0.47817211
146MP0002102_abnormal_ear_morphology0.47744845
147MP0001529_abnormal_vocalization0.45842237
148MP0002111_abnormal_tail_morphology0.45617332
149MP0002229_neurodegeneration0.45071645

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory motile cilium morphology (HP:0005938)9.36601152
2Abnormal respiratory epithelium morphology (HP:0012253)9.36601152
3Absent/shortened dynein arms (HP:0200106)7.74641982
4Dynein arm defect of respiratory motile cilia (HP:0012255)7.74641982
5Chronic bronchitis (HP:0004469)6.74575716
6Bronchiectasis (HP:0002110)5.86110357
7Nasal polyposis (HP:0100582)4.98407005
8Pancreatic fibrosis (HP:0100732)4.58069262
9True hermaphroditism (HP:0010459)4.52393931
10Abnormality of the nasal mucosa (HP:0000433)4.08395620
11Occipital encephalocele (HP:0002085)3.74756668
12Infertility (HP:0000789)3.70744731
13Recurrent sinusitis (HP:0011108)3.66783489
14Tubulointerstitial nephritis (HP:0001970)3.54282038
15Male infertility (HP:0003251)3.46760988
16Bronchitis (HP:0012387)3.46002787
17Abnormal biliary tract physiology (HP:0012439)3.43274886
18Bile duct proliferation (HP:0001408)3.43274886
19Chronic sinusitis (HP:0011109)3.36231662
20Medial flaring of the eyebrow (HP:0010747)3.34883918
21Abnormality of midbrain morphology (HP:0002418)3.32467454
22Molar tooth sign on MRI (HP:0002419)3.32467454
23Pancreatic cysts (HP:0001737)3.27278310
24Nephronophthisis (HP:0000090)3.20389675
25Cystic liver disease (HP:0006706)3.13958489
26Abnormality of dentin (HP:0010299)3.13437516
27Gait imbalance (HP:0002141)3.02967739
28Congenital primary aphakia (HP:0007707)3.02006599
29Median cleft lip (HP:0000161)2.96003416
30Chronic otitis media (HP:0000389)2.95766019
31Supernumerary spleens (HP:0009799)2.83782206
32Postaxial foot polydactyly (HP:0001830)2.83321556
33Aplasia/Hypoplasia of the tongue (HP:0010295)2.75564228
34Nephrogenic diabetes insipidus (HP:0009806)2.73404444
35Congenital hepatic fibrosis (HP:0002612)2.66799902
36Abnormality of permanent molar morphology (HP:0011071)2.61476441
37Abnormality of the dental root (HP:0006486)2.61476441
38Taurodontia (HP:0000679)2.61476441
39Recurrent otitis media (HP:0000403)2.60058646
40Chronic hepatic failure (HP:0100626)2.54928620
41Abnormality of the renal medulla (HP:0100957)2.53112568
42Abnormality of molar morphology (HP:0011070)2.47727439
43Abnormality of molar (HP:0011077)2.47727439
44Male pseudohermaphroditism (HP:0000037)2.46621226
45Hyperactive renin-angiotensin system (HP:0000841)2.46168386
46Abnormality of the dental pulp (HP:0006479)2.35655336
47Genital tract atresia (HP:0001827)2.32418340
48Poor coordination (HP:0002370)2.24777358
49Tubulointerstitial abnormality (HP:0001969)2.23255891
50Anencephaly (HP:0002323)2.22242153
51Vaginal atresia (HP:0000148)2.16529696
52Bifid tongue (HP:0010297)2.14670793
53Postaxial hand polydactyly (HP:0001162)2.13323730
54Short nail (HP:0001799)2.09616198
55Sclerocornea (HP:0000647)2.08520443
56Preaxial hand polydactyly (HP:0001177)2.03499383
57Abnormal respiratory motile cilium physiology (HP:0012261)12.4342079
58Respiratory insufficiency due to defective ciliary clearance (HP:0200073)12.3559110
59Abnormal ciliary motility (HP:0012262)12.1071936
60Rhinitis (HP:0012384)10.2250939
61Tubular atrophy (HP:0000092)1.95732518
62Asplenia (HP:0001746)1.95672896
63Aplasia/Hypoplasia of the spleen (HP:0010451)1.94877235
64Facial cleft (HP:0002006)1.92103376
65Oculomotor apraxia (HP:0000657)1.91327708
66Furrowed tongue (HP:0000221)1.90104495
67Bell-shaped thorax (HP:0001591)1.87179514
68Stage 5 chronic kidney disease (HP:0003774)1.83329120
69Aplasia/Hypoplasia of the lens (HP:0008063)1.82890092
70Fibular hypoplasia (HP:0003038)1.81101642
71Back pain (HP:0003418)1.73661790
72Broad distal phalanx of finger (HP:0009836)1.70644000
73Degeneration of the lateral corticospinal tracts (HP:0002314)1.69773437
74Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.69773437
75Retinal dysplasia (HP:0007973)1.66394447
76Absent frontal sinuses (HP:0002688)1.65115849
77Decreased circulating renin level (HP:0003351)1.59035540
78Abnormality of the fetal cardiovascular system (HP:0010948)1.56119164
79Abnormal umbilical cord blood vessels (HP:0011403)1.56119164
80Single umbilical artery (HP:0001195)1.56119164
81Hypotelorism (HP:0000601)1.54570478
82Polydipsia (HP:0001959)1.51920228
83Abnormal drinking behavior (HP:0030082)1.51920228
84Renal salt wasting (HP:0000127)1.42930661
85Abdominal situs inversus (HP:0003363)1.41753065
86Abnormality of abdominal situs (HP:0011620)1.41753065
87Specific learning disability (HP:0001328)1.36684940
88Neoplasm of head and neck (HP:0012288)1.35649119
89Esophageal neoplasm (HP:0100751)1.35649119
90Broad foot (HP:0001769)1.33304718
91Adrenal hypoplasia (HP:0000835)1.32899462
92Genetic anticipation (HP:0003743)1.32420051
93Tubulointerstitial fibrosis (HP:0005576)1.32167426
94Abnormality of macular pigmentation (HP:0008002)1.31829708
95Abnormality of renal excretion (HP:0011036)1.30753758
96Hyperglycinuria (HP:0003108)1.27317844
97Recurrent bronchitis (HP:0002837)1.26954168
98Retinitis pigmentosa (HP:0000510)1.26680719
99Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.26577093
100Hyperkalemia (HP:0002153)1.25990876
101Atelectasis (HP:0100750)1.25552513
102Hypodontia (HP:0000668)1.25531979
103Nephropathy (HP:0000112)1.24454859
104Abnormality of the renal cortex (HP:0011035)1.24010739
105Hyperaldosteronism (HP:0000859)1.20803341
106Abnormality of the corticospinal tract (HP:0002492)1.18784251
107Bifid scrotum (HP:0000048)1.17820251
108Short thorax (HP:0010306)1.15231837
109Abnormality of renin-angiotensin system (HP:0000847)1.14711772
110Narrow forehead (HP:0000341)1.14110352
111Aplasia/Hypoplasia of the phalanges of the toes (HP:0010173)1.13596466
112Aganglionic megacolon (HP:0002251)1.12263001
113Termporal pattern (HP:0011008)1.11380882
114Insidious onset (HP:0003587)1.11380882
115Decreased central vision (HP:0007663)1.07172722
116Prominent nasal bridge (HP:0000426)1.06949195
117Cone-rod dystrophy (HP:0000548)1.05026046
118Abnormality of chloride homeostasis (HP:0011422)1.01846109
119Abnormality of the frontal sinuses (HP:0002687)1.01684682
120Multicystic kidney dysplasia (HP:0000003)0.96643401
121Aplasia/Hypoplasia involving the sinuses (HP:0009120)0.96575122
122Absent rod-and cone-mediated responses on ERG (HP:0007688)0.94143448
123Holoprosencephaly (HP:0001360)0.92386406

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAPK159.00553648
2PNCK6.00848602
3EPHA23.81829928
4GRK13.23088023
5PDK33.12432977
6PDK43.12432977
7TESK12.86421587
8MST42.55356055
9NME12.15599046
10MAP3K22.14117347
11PTK2B2.00591136
12STK241.96629879
13PDK21.94076033
14ARAF1.69040857
15NTRK21.61734517
16ERBB31.60992347
17WEE11.58536917
18EEF2K1.50837095
19VRK11.47940187
20PRKCG1.39747824
21BMPR21.38624331
22STK391.31432928
23SIK11.31224486
24PHKG11.20426229
25PHKG21.20426229
26PRKD31.17888743
27IRAK11.16973071
28TSSK61.12422063
29STK38L1.09376391
30MAP3K41.08100098
31STK161.07880711
32NEK61.07449972
33TLK11.07071468
34CCNB11.01036975
35EPHB10.99589308
36EPHA30.98387506
37RPS6KA20.97556010
38ICK0.96841254
39CAMKK10.95999566
40PIM20.95683944
41CDK30.95202824
42WNK40.94848668
43MUSK0.91045946
44CDC42BPA0.89840605
45DAPK20.89726337
46CAMKK20.86989389
47STK100.86314507
48PASK0.85455630
49SMG10.85278670
50MAPKAPK30.84862813
51BRSK20.83903019
52NLK0.83161077
53MAP3K70.81335296
54TRPM70.78863559
55CAMK2B0.77544705
56PTK60.77470295
57GSK3A0.72155946
58AURKA0.69968240
59LMTK20.68221763
60WNK30.65877688
61ERBB20.65698295
62PRKCI0.65648874
63MAPKAPK50.64888091
64BMPR1B0.63773134
65LATS10.61632786
66ROCK20.61172710
67BCR0.60148651
68GRK70.59953783
69CAMK1G0.59701926
70INSRR0.59687110
71PRKCE0.59337947
72CAMK2D0.59299143
73MAP2K20.59278765
74IRAK20.57930513
75DYRK30.57315492
76CASK0.55628919
77MAP3K120.54437760
78ITK0.53857087
79CAMK2G0.51920942
80MAP3K90.51571465
81MAPK70.49854088
82MST1R0.49077395
83MARK20.48653886
84CAMK2A0.47476403
85MAP4K20.44373795
86MAP2K70.44366734
87MARK10.43970802
88ROCK10.43779515
89FGFR20.43726934
90EPHA40.43451189
91MAPK120.43411803
92PRKCQ0.43193790
93PBK0.41383802
94PRKG10.40886423
95ADRBK20.38632981
96CSK0.38337523
97ZAK0.37798283
98NTRK30.36439467
99MAPK130.36248792
100PINK10.36065971
101MAP2K40.34997270
102TNIK0.34690586
103TEC0.34339405
104PRKACA0.34169553
105MAPKAPK20.34166050
106STK380.33905979
107DYRK1B0.33793886
108SGK10.33547944
109RPS6KA50.33197617
110TBK10.31460484
111CDK190.31243072
112PRKCD0.30585324
113CSNK1G20.29997292
114PAK20.29809923
115TTK0.29499093
116PDK10.29210977
117SGK2230.29158840
118SGK4940.29158840
119RPS6KB20.29094060
120MAP3K30.29011447
121PRKACG0.28792356
122NEK90.28273030
123MET0.27482084
124CSNK1E0.26446089
125AKT20.26326235
126RPS6KC10.26139877
127RPS6KL10.26139877
128PRKG20.25949986
129SGK20.25671456
130PLK10.25503208
131ADRBK10.24012851
132PRKAA20.23959085
133PRPF4B0.23849671
134GRK50.23213512
135LRRK20.22493011
136LIMK10.22076771
137PRKCZ0.20981140
138DYRK1A0.20630779
139ACVR1B0.20570837
140FRK0.19931731
141TGFBR20.19886822
142PRKCA0.19424535
143TAOK10.19355054
144CDK80.18900310
145OXSR10.18503002
146FER0.16110515
147CDK90.16101592
148ABL10.15895042
149GRK60.14969060
150TGFBR10.13449946

Predicted pathways (KEGG)

RankGene SetZ-score
1Olfactory transduction_Homo sapiens_hsa047405.79853857
2Phenylalanine metabolism_Homo sapiens_hsa003604.24392710
3Synthesis and degradation of ketone bodies_Homo sapiens_hsa000723.87082722
4Huntingtons disease_Homo sapiens_hsa050163.43467036
5Tyrosine metabolism_Homo sapiens_hsa003503.37999043
6beta-Alanine metabolism_Homo sapiens_hsa004102.88420984
7Drug metabolism - cytochrome P450_Homo sapiens_hsa009822.69650293
8Vasopressin-regulated water reabsorption_Homo sapiens_hsa049622.66709998
9Vitamin B6 metabolism_Homo sapiens_hsa007502.42757744
10Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009802.35083549
11Sulfur metabolism_Homo sapiens_hsa009202.27421028
12Propanoate metabolism_Homo sapiens_hsa006402.15473890
13Glutathione metabolism_Homo sapiens_hsa004802.03657395
14Caffeine metabolism_Homo sapiens_hsa002321.96471368
15Chemical carcinogenesis_Homo sapiens_hsa052041.86204953
16Phototransduction_Homo sapiens_hsa047441.85278457
17Ovarian steroidogenesis_Homo sapiens_hsa049131.78381828
18Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.68907724
19PPAR signaling pathway_Homo sapiens_hsa033201.67286842
20Pentose and glucuronate interconversions_Homo sapiens_hsa000401.65177193
21Fatty acid biosynthesis_Homo sapiens_hsa000611.59301165
22Gastric acid secretion_Homo sapiens_hsa049711.50814998
23Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.49397199
24Butanoate metabolism_Homo sapiens_hsa006501.49100556
25Oxidative phosphorylation_Homo sapiens_hsa001901.44403858
26Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.39403945
27Purine metabolism_Homo sapiens_hsa002301.36950161
28Pyruvate metabolism_Homo sapiens_hsa006201.36909319
29Amphetamine addiction_Homo sapiens_hsa050311.35246577
30Arachidonic acid metabolism_Homo sapiens_hsa005901.32824652
31Retinol metabolism_Homo sapiens_hsa008301.30986989
32Taste transduction_Homo sapiens_hsa047421.30970429
33Parkinsons disease_Homo sapiens_hsa050121.28536085
34Insulin secretion_Homo sapiens_hsa049111.28446135
35Fatty acid degradation_Homo sapiens_hsa000711.25896258
36ABC transporters_Homo sapiens_hsa020101.24710257
37Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.23703230
38Circadian entrainment_Homo sapiens_hsa047131.17000919
39Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.14585190
40Histidine metabolism_Homo sapiens_hsa003401.14167859
41Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.12956500
42Cardiac muscle contraction_Homo sapiens_hsa042601.06676030
43Ether lipid metabolism_Homo sapiens_hsa005651.05781678
44Alzheimers disease_Homo sapiens_hsa050101.05611549
45Calcium signaling pathway_Homo sapiens_hsa040201.03203016
46Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.03103968
47Thyroid hormone synthesis_Homo sapiens_hsa049181.02364117
48cAMP signaling pathway_Homo sapiens_hsa040241.00056825
49Mineral absorption_Homo sapiens_hsa049780.99431060
50Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.93932872
51Notch signaling pathway_Homo sapiens_hsa043300.93878496
52Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.93751828
53Glucagon signaling pathway_Homo sapiens_hsa049220.93032854
54Collecting duct acid secretion_Homo sapiens_hsa049660.91394008
55Bile secretion_Homo sapiens_hsa049760.89145346
56GABAergic synapse_Homo sapiens_hsa047270.88831846
57Steroid biosynthesis_Homo sapiens_hsa001000.85286579
58Maturity onset diabetes of the young_Homo sapiens_hsa049500.84498908
59Glutamatergic synapse_Homo sapiens_hsa047240.84164428
60Hedgehog signaling pathway_Homo sapiens_hsa043400.83072722
61Nicotine addiction_Homo sapiens_hsa050330.82130139
62Estrogen signaling pathway_Homo sapiens_hsa049150.81963514
63Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.81720100
64Renin secretion_Homo sapiens_hsa049240.79856584
65Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.79277575
66Cocaine addiction_Homo sapiens_hsa050300.78411753
67cGMP-PKG signaling pathway_Homo sapiens_hsa040220.77694551
68Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.77511464
69Morphine addiction_Homo sapiens_hsa050320.75105076
70Salivary secretion_Homo sapiens_hsa049700.74593144
71Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.72529462
72Linoleic acid metabolism_Homo sapiens_hsa005910.72521919
73Peroxisome_Homo sapiens_hsa041460.71635736
74Pyrimidine metabolism_Homo sapiens_hsa002400.71298483
75Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.69057992
76GnRH signaling pathway_Homo sapiens_hsa049120.68706516
77Dopaminergic synapse_Homo sapiens_hsa047280.68099799
78Aldosterone synthesis and secretion_Homo sapiens_hsa049250.67238019
79Glycerolipid metabolism_Homo sapiens_hsa005610.67149703
80alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.64313580
81Nitrogen metabolism_Homo sapiens_hsa009100.57818400
82Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.57508501
83Basal cell carcinoma_Homo sapiens_hsa052170.57500921
84Carbohydrate digestion and absorption_Homo sapiens_hsa049730.55454941
85Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.54640982
86Systemic lupus erythematosus_Homo sapiens_hsa053220.54487793
87Hippo signaling pathway_Homo sapiens_hsa043900.53518732
88Circadian rhythm_Homo sapiens_hsa047100.52477842
89Protein export_Homo sapiens_hsa030600.51672518
90Arginine and proline metabolism_Homo sapiens_hsa003300.51364434
91Alcoholism_Homo sapiens_hsa050340.50483860
92Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.48823495
93Tight junction_Homo sapiens_hsa045300.48772578
94Vitamin digestion and absorption_Homo sapiens_hsa049770.48623030
95Sphingolipid metabolism_Homo sapiens_hsa006000.47526284
96Starch and sucrose metabolism_Homo sapiens_hsa005000.47395291
97Metabolic pathways_Homo sapiens_hsa011000.46746571
98Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.46650501
99Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.46644759
100Melanogenesis_Homo sapiens_hsa049160.46044853
101Primary bile acid biosynthesis_Homo sapiens_hsa001200.44906914
102Steroid hormone biosynthesis_Homo sapiens_hsa001400.44695340
103Dorso-ventral axis formation_Homo sapiens_hsa043200.44514914
104Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.42202121
105Wnt signaling pathway_Homo sapiens_hsa043100.42196240
106Axon guidance_Homo sapiens_hsa043600.42127112
107Nucleotide excision repair_Homo sapiens_hsa034200.42047828
108Complement and coagulation cascades_Homo sapiens_hsa046100.41922145
109Fanconi anemia pathway_Homo sapiens_hsa034600.40506863
110Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.40402239
111Synaptic vesicle cycle_Homo sapiens_hsa047210.39405865
112Drug metabolism - other enzymes_Homo sapiens_hsa009830.39221185
113Tryptophan metabolism_Homo sapiens_hsa003800.39217272
114Vascular smooth muscle contraction_Homo sapiens_hsa042700.38095928
115Glycerophospholipid metabolism_Homo sapiens_hsa005640.36809000
116Gap junction_Homo sapiens_hsa045400.35278935
117Adherens junction_Homo sapiens_hsa045200.34184277
118Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.33885965
119Carbon metabolism_Homo sapiens_hsa012000.32767766
120Regulation of autophagy_Homo sapiens_hsa041400.32728595
121Prion diseases_Homo sapiens_hsa050200.32300952
122Cholinergic synapse_Homo sapiens_hsa047250.31847316
123Pancreatic secretion_Homo sapiens_hsa049720.31643558
124Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.31460709
125Choline metabolism in cancer_Homo sapiens_hsa052310.30866042
126Vibrio cholerae infection_Homo sapiens_hsa051100.30101639
127Serotonergic synapse_Homo sapiens_hsa047260.29057303
128Sulfur relay system_Homo sapiens_hsa041220.28189783
129Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.27151156
130Folate biosynthesis_Homo sapiens_hsa007900.22258493
131Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.21003293
132Leukocyte transendothelial migration_Homo sapiens_hsa046700.20115209
133TGF-beta signaling pathway_Homo sapiens_hsa043500.19926171
134Transcriptional misregulation in cancer_Homo sapiens_hsa052020.16836781
135N-Glycan biosynthesis_Homo sapiens_hsa005100.16594090
136Hepatitis C_Homo sapiens_hsa051600.15916631
137Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.12945849

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