PIH1D2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of cilium movement (GO:0003352)9.11276924
2maturation of 5.8S rRNA (GO:0000460)8.18438798
3response to xenobiotic stimulus (GO:0009410)7.36143754
4axon ensheathment in central nervous system (GO:0032291)7.35199161
5central nervous system myelination (GO:0022010)7.35199161
6left/right pattern formation (GO:0060972)6.66430179
7striatum development (GO:0021756)6.20456390
8regulation of timing of cell differentiation (GO:0048505)6.15580561
9retinal cone cell development (GO:0046549)5.97881205
10intraciliary transport (GO:0042073)5.88506429
11oligodendrocyte differentiation (GO:0048709)5.83507022
12regulation of microtubule-based movement (GO:0060632)5.77599935
13left/right axis specification (GO:0070986)5.74463184
14cilium organization (GO:0044782)5.73541871
15microtubule bundle formation (GO:0001578)5.70095587
16retinal rod cell development (GO:0046548)5.64146351
17cilium assembly (GO:0042384)5.37562588
18cardiovascular system development (GO:0072358)5.36054172
19regulation of development, heterochronic (GO:0040034)5.31184395
20negative regulation of protein localization to cell surface (GO:2000009)5.04949724
21positive regulation of cellular amide metabolic process (GO:0034250)4.95836979
22photoreceptor cell maintenance (GO:0045494)4.93249253
23L-serine transport (GO:0015825)4.91905851
24cilium morphogenesis (GO:0060271)4.90221215
25grooming behavior (GO:0007625)4.77714284
26response to methylmercury (GO:0051597)4.71177405
27regulation of beta-amyloid formation (GO:1902003)4.67832069
28positive regulation of cellular amine metabolic process (GO:0033240)4.54611986
29fatty acid elongation (GO:0030497)4.54299975
30protein localization to cilium (GO:0061512)4.52736711
31cellular component assembly involved in morphogenesis (GO:0010927)4.38555651
32neuron cell-cell adhesion (GO:0007158)4.37960502
33microtubule-based movement (GO:0007018)4.37170948
34myelination (GO:0042552)4.27759354
35ensheathment of neurons (GO:0007272)4.23338498
36axon ensheathment (GO:0008366)4.23338498
37regulation of amyloid precursor protein catabolic process (GO:1902991)4.18732814
38serine transport (GO:0032329)4.18007563
39dendrite morphogenesis (GO:0048813)4.13358975
40regulation of phospholipid biosynthetic process (GO:0071071)4.11378561
41microtubule depolymerization (GO:0007019)3.95406569
42C4-dicarboxylate transport (GO:0015740)3.91104999
43long-chain fatty acid biosynthetic process (GO:0042759)3.88947421
44presynaptic membrane organization (GO:0097090)3.81697042
45presynaptic membrane assembly (GO:0097105)3.80952678
46determination of left/right symmetry (GO:0007368)3.80673889
47cell projection assembly (GO:0030031)3.78547489
48nonmotile primary cilium assembly (GO:0035058)3.74633079
49nucleoside diphosphate phosphorylation (GO:0006165)3.71277195
50ubiquinone biosynthetic process (GO:0006744)3.68151327
51determination of bilateral symmetry (GO:0009855)3.65525881
52specification of symmetry (GO:0009799)3.59160212
53startle response (GO:0001964)3.57215791
54centriole assembly (GO:0098534)3.47637896
55sperm motility (GO:0030317)3.43590437
56regulation of collateral sprouting (GO:0048670)3.40811036
57limb bud formation (GO:0060174)3.37773117
58ubiquinone metabolic process (GO:0006743)3.34995848
59cilium movement (GO:0003341)3.32871005
60lateral ventricle development (GO:0021670)3.32582330
61positive regulation of action potential (GO:0045760)3.27231806
62mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.27183192
63centriole replication (GO:0007099)3.24934582
64lateral sprouting from an epithelium (GO:0060601)3.24019834
65glial cell differentiation (GO:0010001)3.23939528
66behavioral response to nicotine (GO:0035095)3.23838565
67peptidyl-tyrosine autophosphorylation (GO:0038083)3.22919652
68negative regulation of neurotransmitter transport (GO:0051589)3.20362558
69negative regulation of epidermal growth factor-activated receptor activity (GO:0007175)3.17788754
70alanine transport (GO:0032328)3.17602830
71L-amino acid import (GO:0043092)3.17346349
72righting reflex (GO:0060013)3.15778976
73protein localization to synapse (GO:0035418)3.13722735
74protein polyglutamylation (GO:0018095)3.09004348
75membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.07849440
76cholesterol biosynthetic process (GO:0006695)3.06965700
77microtubule polymerization or depolymerization (GO:0031109)3.06600189
78smoothened signaling pathway (GO:0007224)3.04254167
79response to pheromone (GO:0019236)3.03379048
80import into cell (GO:0098657)3.02831670
81quinone biosynthetic process (GO:1901663)3.01805857
82neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976)3.01700808
83positive regulation of chondrocyte differentiation (GO:0032332)3.01544284
84transmission of nerve impulse (GO:0019226)3.00476604
85establishment of protein localization to mitochondrial membrane (GO:0090151)2.99897501
86polyol transport (GO:0015791)2.99150709
87response to epinephrine (GO:0071871)2.95684583
88very-low-density lipoprotein particle assembly (GO:0034379)2.94185896
89negative regulation of T cell differentiation in thymus (GO:0033085)2.92538873
90GTP biosynthetic process (GO:0006183)2.92421503
91chondroitin sulfate catabolic process (GO:0030207)2.91563735
92astrocyte development (GO:0014002)2.91472396
93glycerophospholipid catabolic process (GO:0046475)2.91198228
94substantia nigra development (GO:0021762)2.90736432
95axon development (GO:0061564)2.89345041
96regulation of Golgi to plasma membrane protein transport (GO:0042996)2.87377411
97GPI anchor biosynthetic process (GO:0006506)2.87034884
98negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)2.86036630
99negative regulation of T-helper cell differentiation (GO:0045623)2.86036630
100dermatan sulfate biosynthetic process (GO:0030208)2.85819685
101negative regulation of neurotransmitter secretion (GO:0046929)2.85625247
102chaperone-mediated protein transport (GO:0072321)2.80106587
103exogenous drug catabolic process (GO:0042738)2.79584837
104microtubule-based process (GO:0007017)2.79034183
105positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.77728273
106mitochondrial ATP synthesis coupled proton transport (GO:0042776)2.76986454
107piRNA metabolic process (GO:0034587)2.76762906
108sarcoplasmic reticulum calcium ion transport (GO:0070296)2.76299131
109negative regulation of axon extension (GO:0030517)2.76206405
110energy coupled proton transport, down electrochemical gradient (GO:0015985)2.75450690
111ATP synthesis coupled proton transport (GO:0015986)2.75450690
112axonemal dynein complex assembly (GO:0070286)2.73667146
113positive regulation of synapse assembly (GO:0051965)2.72855420
114sperm capacitation (GO:0048240)2.72275302
115neuronal action potential propagation (GO:0019227)2.72144892
116cytoplasmic microtubule organization (GO:0031122)2.71204750
117primary alcohol catabolic process (GO:0034310)2.68987284
118regulation of cellular amide metabolic process (GO:0034248)2.68398151
119GPI anchor metabolic process (GO:0006505)2.67857666
120phenol-containing compound catabolic process (GO:0019336)2.67048613
121negative regulation of receptor activity (GO:2000272)2.66795864
122basic amino acid transport (GO:0015802)2.66340548
123head development (GO:0060322)2.65094361
124activation of protein kinase B activity (GO:0032148)2.64956916
125inner ear receptor cell differentiation (GO:0060113)2.64913779
126amino acid import (GO:0043090)2.64703279
127brain morphogenesis (GO:0048854)2.64064206
128cranial suture morphogenesis (GO:0060363)2.63009198
129viral protein processing (GO:0019082)2.61955349
130myelin maintenance (GO:0043217)2.60321573
131cilium or flagellum-dependent cell motility (GO:0001539)2.59375583
132neurotransmitter catabolic process (GO:0042135)2.58929945
133neuron recognition (GO:0008038)2.58385563
134multicellular organismal aging (GO:0010259)2.58367994
135sterol biosynthetic process (GO:0016126)2.56436007
136UTP biosynthetic process (GO:0006228)2.56345426
137photoreceptor cell development (GO:0042461)2.55878649
138diterpenoid biosynthetic process (GO:0016102)2.55216298
139preassembly of GPI anchor in ER membrane (GO:0016254)2.54891128
140apical protein localization (GO:0045176)2.54529355
141ventricular system development (GO:0021591)2.54311091
142dermatan sulfate metabolic process (GO:0030205)2.54046223
143negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)2.53611910
144amyloid precursor protein metabolic process (GO:0042982)2.53495217
145drug catabolic process (GO:0042737)2.53494014
146astrocyte differentiation (GO:0048708)2.53232598
147adhesion of symbiont to host (GO:0044406)2.52932491
148negative regulation of axonogenesis (GO:0050771)2.52486036
149keratan sulfate biosynthetic process (GO:0018146)2.52443536
150gamma-aminobutyric acid signaling pathway (GO:0007214)2.51720967
151respiratory electron transport chain (GO:0022904)2.51138781
152proteasome assembly (GO:0043248)2.50081885
153dopamine biosynthetic process (GO:0042416)2.49661273
154organelle disassembly (GO:1903008)2.45322582
155organelle assembly (GO:0070925)2.42912618
156positive regulation of sodium ion transmembrane transporter activity (GO:2000651)2.41391353
157eye photoreceptor cell development (GO:0042462)2.39658440
158pyrimidine-containing compound transmembrane transport (GO:0072531)2.38187436
159UTP metabolic process (GO:0046051)2.31683824
160establishment of planar polarity (GO:0001736)2.29857345
161establishment of tissue polarity (GO:0007164)2.29857345
162spermatid development (GO:0007286)2.29294979
163aldehyde catabolic process (GO:0046185)2.27580252
164retinoic acid metabolic process (GO:0042573)2.27392385
165terpenoid biosynthetic process (GO:0016114)2.26738183
166vitamin transmembrane transport (GO:0035461)2.24874494
167one-carbon compound transport (GO:0019755)2.21714027
168heart looping (GO:0001947)2.20779471
169intra-S DNA damage checkpoint (GO:0031573)2.20745416
170fucose catabolic process (GO:0019317)2.20065602
171L-fucose metabolic process (GO:0042354)2.20065602
172L-fucose catabolic process (GO:0042355)2.20065602
173ethanol metabolic process (GO:0006067)2.19557440
174regulation of meiosis I (GO:0060631)2.16517863
175calcium ion-dependent exocytosis (GO:0017156)2.16431839
176nucleotide phosphorylation (GO:0046939)2.16103402
177positive regulation of sodium ion transmembrane transport (GO:1902307)2.15836162
178protein import into peroxisome matrix (GO:0016558)2.15542697
179lung epithelium development (GO:0060428)2.12355269
180pyrimidine nucleobase catabolic process (GO:0006208)2.12004178
181acrosome reaction (GO:0007340)2.10795852
182DNA methylation involved in gamete generation (GO:0043046)2.10358941
183glutathione derivative metabolic process (GO:1901685)2.09975517
184glutathione derivative biosynthetic process (GO:1901687)2.09975517
185myoblast migration (GO:0051451)2.06575178
186respiratory chain complex IV assembly (GO:0008535)2.03881735
187limb development (GO:0060173)2.02364021
188epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)14.4211988
189epithelial cilium movement (GO:0003351)12.4644447
190motile cilium assembly (GO:0044458)11.2875094
191axoneme assembly (GO:0035082)10.7035063

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1BP1_19119308_ChIP-ChIP_Hs578T_Human3.67295028
2FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse3.47451339
3TAF15_26573619_Chip-Seq_HEK293_Human3.21197460
4EZH2_22144423_ChIP-Seq_EOC_Human3.20739613
5GBX2_23144817_ChIP-Seq_PC3_Human3.10962302
6JARID2_20064375_ChIP-Seq_MESCs_Mouse2.62584301
7SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.58896078
8SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.54844609
9ZFP57_27257070_Chip-Seq_ESCs_Mouse2.42228888
10HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.35797554
11RBPJ_22232070_ChIP-Seq_NCS_Mouse2.28096336
12SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.25919527
13SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.22022737
14TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.18491368
15SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.10963663
16RNF2_18974828_ChIP-Seq_MESCs_Mouse2.10269490
17EZH2_18974828_ChIP-Seq_MESCs_Mouse2.10269490
18EED_16625203_ChIP-ChIP_MESCs_Mouse2.06253111
19CTBP1_25329375_ChIP-Seq_LNCAP_Human2.04687776
20SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.04667162
21EZH2_27304074_Chip-Seq_ESCs_Mouse2.01756648
22JARID2_20075857_ChIP-Seq_MESCs_Mouse2.01738287
23SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.99974756
24GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.98314452
25CTBP2_25329375_ChIP-Seq_LNCAP_Human1.98110412
26E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.94873182
27MTF2_20144788_ChIP-Seq_MESCs_Mouse1.91761888
28CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.87630928
29SMAD3_21741376_ChIP-Seq_EPCs_Human1.86880469
30POU3F2_20337985_ChIP-ChIP_501MEL_Human1.86263989
31SUZ12_27294783_Chip-Seq_ESCs_Mouse1.85837895
32EZH2_27294783_Chip-Seq_ESCs_Mouse1.85334144
33GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.85208409
34SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.85023957
35CBX2_27304074_Chip-Seq_ESCs_Mouse1.82627264
36PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.81884781
37P300_19829295_ChIP-Seq_ESCs_Human1.80928064
38ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.80212265
39CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.77236138
40NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.76262497
41FUS_26573619_Chip-Seq_HEK293_Human1.72203506
42CDX2_19796622_ChIP-Seq_MESCs_Mouse1.70437954
43PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.68624889
44* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.68276065
45BMI1_23680149_ChIP-Seq_NPCS_Mouse1.67408219
46GABP_17652178_ChIP-ChIP_JURKAT_Human1.66925424
47RNF2_27304074_Chip-Seq_ESCs_Mouse1.66856654
48NR3C1_21868756_ChIP-Seq_MCF10A_Human1.65938373
49IGF1R_20145208_ChIP-Seq_DFB_Human1.62963614
50STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.62870718
51OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.62124482
52IKZF1_21737484_ChIP-ChIP_HCT116_Human1.61270922
53AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.60400460
54ZNF274_21170338_ChIP-Seq_K562_Hela1.59739453
55EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.58497254
56CBP_20019798_ChIP-Seq_JUKART_Human1.46947166
57IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.46947166
58RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.45829661
59BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.45682050
60IRF1_19129219_ChIP-ChIP_H3396_Human1.44963397
61TCF4_22108803_ChIP-Seq_LS180_Human1.44271905
62TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.38710075
63AR_21572438_ChIP-Seq_LNCaP_Human1.38564204
64PCGF2_27294783_Chip-Seq_ESCs_Mouse1.38545813
65SOX2_19829295_ChIP-Seq_ESCs_Human1.38144459
66NANOG_19829295_ChIP-Seq_ESCs_Human1.38144459
67EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.37834324
68PIAS1_25552417_ChIP-Seq_VCAP_Human1.37248769
69SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.36829851
70* FOXA1_27270436_Chip-Seq_PROSTATE_Human1.34148983
71* FOXA1_25329375_ChIP-Seq_VCAP_Human1.34148983
72NANOG_18555785_Chip-Seq_ESCs_Mouse1.33669309
73CMYC_18555785_Chip-Seq_ESCs_Mouse1.33560407
74FLI1_27457419_Chip-Seq_LIVER_Mouse1.33390410
75TOP2B_26459242_ChIP-Seq_MCF-7_Human1.32655452
76RNF2_27304074_Chip-Seq_NSC_Mouse1.32431335
77PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.30933207
78FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.29194163
79LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse1.28454665
80SMAD4_21799915_ChIP-Seq_A2780_Human1.28425208
81CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.28238726
82* AR_20517297_ChIP-Seq_VCAP_Human1.28131524
83FOXM1_26456572_ChIP-Seq_MCF-7_Human1.27384956
84PCGF2_27294783_Chip-Seq_NPCs_Mouse1.26581068
85REST_21632747_ChIP-Seq_MESCs_Mouse1.26561899
86TRIM28_21343339_ChIP-Seq_HEK293_Human1.26320751
87CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.26208520
88ELF1_17652178_ChIP-ChIP_JURKAT_Human1.26075422
89EWS_26573619_Chip-Seq_HEK293_Human1.25888680
90PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.25401250
91ER_23166858_ChIP-Seq_MCF-7_Human1.25398676
92SUZ12_18555785_Chip-Seq_ESCs_Mouse1.24788241
93P300_18555785_Chip-Seq_ESCs_Mouse1.23565742
94E2F1_18555785_Chip-Seq_ESCs_Mouse1.21592041
95SMAD4_21741376_ChIP-Seq_EPCs_Human1.21376743
96SUZ12_27294783_Chip-Seq_NPCs_Mouse1.20849470
97TAL1_26923725_Chip-Seq_HPCs_Mouse1.19862938
98TP53_22573176_ChIP-Seq_HFKS_Human1.19493832
99* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.18745952
100EST1_17652178_ChIP-ChIP_JURKAT_Human1.18521767
101SALL1_21062744_ChIP-ChIP_HESCs_Human1.18291616
102STAT3_23295773_ChIP-Seq_U87_Human1.17426006
103* SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.16188718
104TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.16020160
105KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.15859529
106* FOXA1_21572438_ChIP-Seq_LNCaP_Human1.15581974
107P53_22387025_ChIP-Seq_ESCs_Mouse1.14873194
108EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.14808551
109EZH2_27294783_Chip-Seq_NPCs_Mouse1.12730967
110MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.12465560
111TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.12225679
112AR_25329375_ChIP-Seq_VCAP_Human1.11735369
113WT1_19549856_ChIP-ChIP_CCG9911_Human1.11701647
114CDX2_22108803_ChIP-Seq_LS180_Human1.10753462
115VDR_22108803_ChIP-Seq_LS180_Human1.09974713
116UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.09673096
117PRDM14_20953172_ChIP-Seq_ESCs_Human1.09592015
118TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.09503495
119POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.09503495
120SOX2_18555785_Chip-Seq_ESCs_Mouse1.09373253
121STAT3_18555785_Chip-Seq_ESCs_Mouse1.09190092
122ETV1_20927104_ChIP-Seq_GIST48_Human1.09099828
123NFE2_27457419_Chip-Seq_LIVER_Mouse1.08569024
124KLF5_20875108_ChIP-Seq_MESCs_Mouse1.07767676
125REST_18959480_ChIP-ChIP_MESCs_Mouse1.07423651
126RUNX2_22187159_ChIP-Seq_PCA_Human1.07239841
127MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.06772711
128GATA3_21878914_ChIP-Seq_MCF-7_Human1.06632631
129JUN_21703547_ChIP-Seq_K562_Human1.05144862
130TP53_18474530_ChIP-ChIP_U2OS_Human1.05064754
131TCF4_23295773_ChIP-Seq_U87_Human1.04666581
132POU5F1_16153702_ChIP-ChIP_HESCs_Human1.04397375
133AUTS2_25519132_ChIP-Seq_293T-REX_Human1.03162602
134TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.03103576
135PCGF4_22325352_ChIP-Seq_293T-Rex_Human1.02891866
136BCAT_22108803_ChIP-Seq_LS180_Human1.02842718
137ZNF217_24962896_ChIP-Seq_MCF-7_Human1.02665082
138PHF8_20622853_ChIP-Seq_HELA_Human1.02406946
139TBL1_22424771_ChIP-Seq_293T_Human1.02335372
140ERG_20517297_ChIP-Seq_VCAP_Human1.02306015
141CDX2_21074721_ChIP-Seq_CACO-2_Mouse1.02253763
142DROSHA_22980978_ChIP-Seq_HELA_Human1.01768550
143SMRT_27268052_Chip-Seq_Bcells_Human1.01430952
144KLF4_18555785_Chip-Seq_ESCs_Mouse1.00799528
145BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.00430202
146NFYA_21822215_ChIP-Seq_K562_Human0.99477574
147MYC_19829295_ChIP-Seq_ESCs_Human0.97681773
148GATA1_26923725_Chip-Seq_HPCs_Mouse0.97340164

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004270_analgesia4.87141309
2MP0002653_abnormal_ependyma_morphology4.70566467
3MP0008875_abnormal_xenobiotic_pharmacok3.92490458
4MP0003880_abnormal_central_pattern3.72366856
5MP0003011_delayed_dark_adaptation3.23066112
6MP0001440_abnormal_grooming_behavior3.19042826
7MP0000920_abnormal_myelination3.02886467
8MP0005171_absent_coat_pigmentation2.83687056
9MP0004133_heterotaxia2.74859940
10MP0003136_yellow_coat_color2.69887633
11MP0009046_muscle_twitch2.63849259
12MP0004859_abnormal_synaptic_plasticity2.61242932
13MP0009745_abnormal_behavioral_response2.61170122
14MP0001486_abnormal_startle_reflex2.56895917
15MP0002139_abnormal_hepatobiliary_system2.48949257
16MP0002064_seizures2.47455668
17MP0002734_abnormal_mechanical_nocicepti2.41296480
18MP0001968_abnormal_touch/_nociception2.36731944
19MP0003878_abnormal_ear_physiology2.35815508
20MP0005377_hearing/vestibular/ear_phenot2.35815508
21MP0003635_abnormal_synaptic_transmissio2.34641833
22MP0004043_abnormal_pH_regulation2.33552732
23MP0003690_abnormal_glial_cell2.31480256
24MP0002572_abnormal_emotion/affect_behav2.31190743
25MP0002736_abnormal_nociception_after2.28753215
26MP0000778_abnormal_nervous_system2.25363077
27MP0002272_abnormal_nervous_system2.21855063
28MP0004142_abnormal_muscle_tone2.17386145
29MP0008789_abnormal_olfactory_epithelium2.16874432
30MP0001529_abnormal_vocalization2.12581492
31MP0002160_abnormal_reproductive_system2.07402508
32MP0003950_abnormal_plasma_membrane2.03866338
33MP0001905_abnormal_dopamine_level2.03162901
34MP0000569_abnormal_digit_pigmentation2.00022964
35MP0003938_abnormal_ear_development1.99627780
36MP0004742_abnormal_vestibular_system1.98161227
37MP0002132_abnormal_respiratory_system1.83804393
38MP0000383_abnormal_hair_follicle1.83801789
39MP0003634_abnormal_glial_cell1.78514716
40MP0003329_amyloid_beta_deposits1.73916735
41MP0002282_abnormal_trachea_morphology1.73308291
42MP0010030_abnormal_orbit_morphology1.64159875
43MP0000462_abnormal_digestive_system1.62616847
44MP0002638_abnormal_pupillary_reflex1.61672804
45MP0002063_abnormal_learning/memory/cond1.61542042
46MP0001346_abnormal_lacrimal_gland1.59545865
47MP0005623_abnormal_meninges_morphology1.59458863
48MP0002184_abnormal_innervation1.59395848
49MP0005409_darkened_coat_color1.58265841
50MP0005394_taste/olfaction_phenotype1.57951306
51MP0005499_abnormal_olfactory_system1.57951306
52MP0000427_abnormal_hair_cycle1.56760871
53MP0001293_anophthalmia1.54052988
54MP0001970_abnormal_pain_threshold1.53517795
55MP0002733_abnormal_thermal_nociception1.52707001
56MP0006276_abnormal_autonomic_nervous1.50755567
57MP0002067_abnormal_sensory_capabilities1.49533620
58MP0001984_abnormal_olfaction1.48089753
59MP0005410_abnormal_fertilization1.47406100
60MP0005379_endocrine/exocrine_gland_phen1.47371403
61MP0008872_abnormal_physiological_respon1.45410670
62MP0002277_abnormal_respiratory_mucosa1.44139694
63MP0003137_abnormal_impulse_conducting1.43754831
64MP0005551_abnormal_eye_electrophysiolog1.43502292
65MP0003632_abnormal_nervous_system1.40765945
66MP0010678_abnormal_skin_adnexa1.38999056
67MP0002882_abnormal_neuron_morphology1.37189212
68MP0005389_reproductive_system_phenotype1.36072659
69MP0002735_abnormal_chemical_nociception1.34712571
70MP0009780_abnormal_chondrocyte_physiolo1.33938199
71MP0000566_synostosis1.33758254
72MP0003195_calcinosis1.31362782
73MP0005083_abnormal_biliary_tract1.29384429
74MP0002752_abnormal_somatic_nervous1.27952051
75MP0004381_abnormal_hair_follicle1.27669228
76MP0008995_early_reproductive_senescence1.26868299
77MP0001501_abnormal_sleep_pattern1.26532510
78MP0002229_neurodegeneration1.25160001
79MP0004145_abnormal_muscle_electrophysio1.24787233
80MP0005253_abnormal_eye_physiology1.21513055
81MP0005423_abnormal_somatic_nervous1.20543354
82MP0001485_abnormal_pinna_reflex1.19872935
83MP0000955_abnormal_spinal_cord1.19650899
84MP0005391_vision/eye_phenotype1.19502894
85MP0003879_abnormal_hair_cell1.17280037
86MP0004885_abnormal_endolymph1.16846561
87MP0003698_abnormal_male_reproductive1.13290503
88MP0004924_abnormal_behavior1.13193791
89MP0005386_behavior/neurological_phenoty1.13193791
90MP0003937_abnormal_limbs/digits/tail_de1.12521302
91MP0001929_abnormal_gametogenesis1.11840060
92MP0008569_lethality_at_weaning1.10921072
93MP0001177_atelectasis1.09213625
94MP0002557_abnormal_social/conspecific_i1.07299323
95MP0005535_abnormal_body_temperature1.07286378
96MP0002102_abnormal_ear_morphology1.06756593
97MP0001943_abnormal_respiration1.06369886
98MP0009379_abnormal_foot_pigmentation1.06062498
99MP0003787_abnormal_imprinting1.04813902
100MP0002909_abnormal_adrenal_gland1.04356081
101MP0002066_abnormal_motor_capabilities/c1.04103979
102MP0005195_abnormal_posterior_eye1.01683066
103MP0001188_hyperpigmentation1.01243548
104MP0001963_abnormal_hearing_physiology1.00738100
105MP0003122_maternal_imprinting1.00229775
106MP0001986_abnormal_taste_sensitivity1.00047525
107MP0001727_abnormal_embryo_implantation0.99108325
108MP0000026_abnormal_inner_ear0.98069368
109MP0003718_maternal_effect0.96444073
110MP0005408_hypopigmentation0.95101945
111MP0008877_abnormal_DNA_methylation0.94954367
112MP0005220_abnormal_exocrine_pancreas0.94471572
113MP0000372_irregular_coat_pigmentation0.93545763
114MP0004019_abnormal_vitamin_homeostasis0.92678484
115MP0002822_catalepsy0.92260725
116MP0003942_abnormal_urinary_system0.90332302
117MP0005645_abnormal_hypothalamus_physiol0.89910632
118MP0003121_genomic_imprinting0.89283163
119MP0003631_nervous_system_phenotype0.89218755
120MP0002090_abnormal_vision0.87353141
121MP0004147_increased_porphyrin_level0.86675987
122MP0005646_abnormal_pituitary_gland0.86491826
123MP0005248_abnormal_Harderian_gland0.84320232
124MP0005636_abnormal_mineral_homeostasis0.84135986
125MP0002152_abnormal_brain_morphology0.83657066
126MP0002210_abnormal_sex_determination0.82576132
127MP0001502_abnormal_circadian_rhythm0.82569850
128MP0002295_abnormal_pulmonary_circulatio0.81174737
129MP0008058_abnormal_DNA_repair0.79399451
130MP0010386_abnormal_urinary_bladder0.78960603
131MP0003646_muscle_fatigue0.78896770
132MP0006082_CNS_inflammation0.78820772
133MP0004085_abnormal_heartbeat0.74837900
134MP0000604_amyloidosis0.71348291
135MP0010368_abnormal_lymphatic_system0.70856063
136MP0006072_abnormal_retinal_apoptosis0.70811878
137MP0001664_abnormal_digestion0.69405366
138MP0006292_abnormal_olfactory_placode0.68777831
139MP0002133_abnormal_respiratory_system0.68596254
140MP0005388_respiratory_system_phenotype0.68596254
141MP0003633_abnormal_nervous_system0.67862188
142MP0000579_abnormal_nail_morphology0.66721181
143MP0000631_abnormal_neuroendocrine_gland0.66000374
144MP0002249_abnormal_larynx_morphology0.65648293
145MP0001270_distended_abdomen0.63087880
146MP0003755_abnormal_palate_morphology0.62963011
147MP0002876_abnormal_thyroid_physiology0.61412550
148MP0002177_abnormal_outer_ear0.58591123
149MP0008057_abnormal_DNA_replication0.57746848
150MP0000747_muscle_weakness0.56130943
151MP0002938_white_spotting0.55758535
152MP0002233_abnormal_nose_morphology0.53186897
153MP0002751_abnormal_autonomic_nervous0.52068541

Predicted human phenotypes

RankGene SetZ-score
1Chronic bronchitis (HP:0004469)6.23381623
2Bronchiectasis (HP:0002110)5.64013456
3Nasal polyposis (HP:0100582)4.89426066
4Chronic hepatic failure (HP:0100626)4.86355108
5Dynein arm defect of respiratory motile cilia (HP:0012255)4.72965098
6Absent/shortened dynein arms (HP:0200106)4.72965098
7Respiratory insufficiency due to defective ciliary clearance (HP:0200073)4.71479029
8Focal motor seizures (HP:0011153)4.63615799
9Absent rod-and cone-mediated responses on ERG (HP:0007688)4.53731494
10Abnormal ciliary motility (HP:0012262)4.30916725
11Renal Fanconi syndrome (HP:0001994)4.25913690
12Pancreatic fibrosis (HP:0100732)4.20222744
13Sensory axonal neuropathy (HP:0003390)4.19020327
14Degeneration of the lateral corticospinal tracts (HP:0002314)4.13354763
15Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)4.13354763
16Abnormal respiratory motile cilium physiology (HP:0012261)4.13192099
17Neurofibrillary tangles (HP:0002185)4.10458489
18True hermaphroditism (HP:0010459)4.05018039
19Abnormality of the nasal mucosa (HP:0000433)3.92441397
20Molar tooth sign on MRI (HP:0002419)3.90223218
21Abnormality of midbrain morphology (HP:0002418)3.90223218
22Abnormal respiratory epithelium morphology (HP:0012253)3.71407753
23Abnormal respiratory motile cilium morphology (HP:0005938)3.71407753
24Pancreatic cysts (HP:0001737)3.68246574
25Nephronophthisis (HP:0000090)3.66050785
26Occipital encephalocele (HP:0002085)3.61558331
27Cupped ear (HP:0000378)3.60133528
28Bronchitis (HP:0012387)3.53921248
29Sparse lateral eyebrow (HP:0005338)3.51753708
30Parakeratosis (HP:0001036)3.50483135
31Increased intramyocellular lipid droplets (HP:0012240)3.50365801
32Increased hepatocellular lipid droplets (HP:0006565)3.49042019
33Recurrent sinusitis (HP:0011108)3.39309746
34Muscle abnormality related to mitochondrial dysfunction (HP:0003800)3.37356203
35Infertility (HP:0000789)3.24804929
36Chronic sinusitis (HP:0011109)3.16574388
37Abnormal rod and cone electroretinograms (HP:0008323)3.07657583
38Cerebral inclusion bodies (HP:0100314)3.06240738
39Medial flaring of the eyebrow (HP:0010747)3.02124736
40Abnormality of the renal medulla (HP:0100957)2.99004952
41Cystic liver disease (HP:0006706)2.98446767
42Peripheral hypomyelination (HP:0007182)2.96481001
43Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.92120377
44Abnormality of renal resorption (HP:0011038)2.91969485
45Abnormality of the corticospinal tract (HP:0002492)2.91827229
46Hyperventilation (HP:0002883)2.90718709
47Lipid accumulation in hepatocytes (HP:0006561)2.87961313
48Poor suck (HP:0002033)2.87340541
49Recurrent otitis media (HP:0000403)2.84492914
50Abnormality of secondary sexual hair (HP:0009888)2.77201020
51Abnormality of the axillary hair (HP:0100134)2.77201020
52Rhinitis (HP:0012384)2.74526481
53Tubulointerstitial nephritis (HP:0001970)2.70252120
54Increased muscle lipid content (HP:0009058)2.70014548
55Alacrima (HP:0000522)2.69835378
56Myokymia (HP:0002411)2.68095969
57Exercise-induced myalgia (HP:0003738)2.59164660
58Postaxial foot polydactyly (HP:0001830)2.54516018
59Cerebral hypomyelination (HP:0006808)2.53358421
60Congenital primary aphakia (HP:0007707)2.50074608
61Gait imbalance (HP:0002141)2.49613345
62Visual hallucinations (HP:0002367)2.49173805
63Myoglobinuria (HP:0002913)2.47929492
64Spastic gait (HP:0002064)2.44442269
65Leukodystrophy (HP:0002415)2.41013224
66Scotoma (HP:0000575)2.40557768
67Aplasia/Hypoplasia of the tongue (HP:0010295)2.38150224
68Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.36682347
69Congenital hepatic fibrosis (HP:0002612)2.35831256
70Acute necrotizing encephalopathy (HP:0006965)2.30413970
71Broad-based gait (HP:0002136)2.28916091
72Abnormality of the parathyroid morphology (HP:0011766)2.27394793
73Tubular atrophy (HP:0000092)2.26135798
74Anencephaly (HP:0002323)2.25434431
75Decreased lacrimation (HP:0000633)2.25396143
76Nephrogenic diabetes insipidus (HP:0009806)2.23733792
77Mitochondrial inheritance (HP:0001427)2.22706062
78Exertional dyspnea (HP:0002875)2.19707531
79Sclerocornea (HP:0000647)2.19107642
80Male pseudohermaphroditism (HP:0000037)2.17188562
81Hypoplastic pelvis (HP:0008839)2.16972103
823-Methylglutaconic aciduria (HP:0003535)2.15138500
83Infantile muscular hypotonia (HP:0008947)2.11965470
84Absent septum pellucidum (HP:0001331)2.10119417
85Atonic seizures (HP:0010819)2.08404730
86Conical tooth (HP:0000698)2.06930738
87Anxiety (HP:0000739)2.06124505
88Polyphagia (HP:0002591)2.03942156
89Chronic otitis media (HP:0000389)2.02632033
90Focal seizures (HP:0007359)2.01581200
91Decreased circulating renin level (HP:0003351)1.99983114
92Bony spicule pigmentary retinopathy (HP:0007737)1.96197661
93Abnormality of incisor morphology (HP:0011063)1.94959641
94Type II lissencephaly (HP:0007260)1.93027758
95Mixed hearing impairment (HP:0000410)1.93001450
96Cerebral hemorrhage (HP:0001342)1.92014883
97Metabolic alkalosis (HP:0200114)1.92011498
98Postaxial hand polydactyly (HP:0001162)1.91765315
99Hyperactive renin-angiotensin system (HP:0000841)1.91546478
100Patchy hypopigmentation of hair (HP:0011365)1.91373058
101Furrowed tongue (HP:0000221)1.89877930
102Progressive macrocephaly (HP:0004481)1.89791876
103Nonprogressive disorder (HP:0003680)1.89645819
104Gaze-evoked nystagmus (HP:0000640)1.89215032
105Absence seizures (HP:0002121)1.88248667
106Abnormality of the renal cortex (HP:0011035)1.87179561
107Thickened helices (HP:0000391)1.86015146
108Morphological abnormality of the inner ear (HP:0011390)1.84157332
109Constricted visual fields (HP:0001133)1.83718281
110Dialeptic seizures (HP:0011146)1.83233677
111Male infertility (HP:0003251)1.82579872
112Dysmetria (HP:0001310)1.82456160
113Hyperphosphaturia (HP:0003109)1.81759750
114Nasal speech (HP:0001611)1.81742842
115Oculomotor apraxia (HP:0000657)1.81667261
116Adrenal hypoplasia (HP:0000835)1.80360555
117Acute encephalopathy (HP:0006846)1.79469950
118White forelock (HP:0002211)1.79068133
119Decreased central vision (HP:0007663)1.78708202
120Spastic paraparesis (HP:0002313)1.78506325
121Abnormality of the septum pellucidum (HP:0007375)1.78037657
122Abnormal auditory evoked potentials (HP:0006958)1.77319238
123Vaginal atresia (HP:0000148)1.77213037
124Akinesia (HP:0002304)1.76915129
125Bell-shaped thorax (HP:0001591)1.76341414
126Hypoplastic nipples (HP:0002557)1.75712106
127Optic disc pallor (HP:0000543)1.74166467
128Exercise intolerance (HP:0003546)1.73437905
129Abnormal mitochondria in muscle tissue (HP:0008316)1.73208824
130Clonus (HP:0002169)1.73173834
131Genital tract atresia (HP:0001827)1.73092691
132Generalized myoclonic seizures (HP:0002123)1.72957278
133Retinal dysplasia (HP:0007973)1.71856884
134Preaxial hand polydactyly (HP:0001177)1.70304866
135Widely spaced teeth (HP:0000687)1.70244732
136Prolonged QT interval (HP:0001657)1.69153377
137Abnormal urine phosphate concentration (HP:0012599)1.68870109
138Recurrent bronchitis (HP:0002837)1.68667240
139Anteriorly placed anus (HP:0001545)1.68427499
140Retinitis pigmentosa (HP:0000510)1.68283499
141Large for gestational age (HP:0001520)1.67422768
142Hypomagnesemia (HP:0002917)1.65698640
143Slow saccadic eye movements (HP:0000514)1.65191853
144Autoamputation (HP:0001218)1.64997190
145Aplasia involving bones of the upper limbs (HP:0009823)1.64429007
146Aplasia of the phalanges of the hand (HP:0009802)1.64429007
147Aplasia involving bones of the extremities (HP:0009825)1.64429007
148Esotropia (HP:0000565)1.63869135
149Poor coordination (HP:0002370)1.63804194
150Bile duct proliferation (HP:0001408)1.63397118
151Abnormal biliary tract physiology (HP:0012439)1.63397118
152Congenital malformation of the right heart (HP:0011723)1.63099957
153Double outlet right ventricle (HP:0001719)1.63099957
154Tubulointerstitial abnormality (HP:0001969)1.60885487
155Supernumerary spleens (HP:0009799)1.59751613
156Atelectasis (HP:0100750)1.54203748
157Anophthalmia (HP:0000528)1.50548072
158Cone-rod dystrophy (HP:0000548)1.50262258
159Median cleft lip (HP:0000161)1.49446556
160Multicystic kidney dysplasia (HP:0000003)1.45180825
161Aplasia/Hypoplasia of the spleen (HP:0010451)1.44794122
162Pendular nystagmus (HP:0012043)1.40080195
163Nephropathy (HP:0000112)1.38516989
164Abnormal drinking behavior (HP:0030082)1.38202162
165Polydipsia (HP:0001959)1.38202162
166Asplenia (HP:0001746)1.36806727
167Prominent nasal bridge (HP:0000426)1.36386098
168Aganglionic megacolon (HP:0002251)1.35914744
169Abolished electroretinogram (ERG) (HP:0000550)1.35512420
170Brushfield spots (HP:0001088)1.34016787
171Narrow forehead (HP:0000341)1.33677290
172Cerebellar dysplasia (HP:0007033)1.29974871
173Optic nerve coloboma (HP:0000588)1.29030889
174Abnormality of renin-angiotensin system (HP:0000847)1.25877832
175Renal salt wasting (HP:0000127)1.24533694
176Stage 5 chronic kidney disease (HP:0003774)1.22687379
177Abdominal situs inversus (HP:0003363)1.21280270
178Abnormality of abdominal situs (HP:0011620)1.21280270
179Hepatocellular necrosis (HP:0001404)1.18347877
180Bifid tongue (HP:0010297)1.18127744
181Fetal akinesia sequence (HP:0001989)1.16555953
182Left ventricular hypertrophy (HP:0001712)1.13960905
183Increased corneal curvature (HP:0100692)1.13213829
184Keratoconus (HP:0000563)1.13213829
185Hyperglycinemia (HP:0002154)1.12312491
186Aplasia/Hypoplasia of the lens (HP:0008063)1.12142856

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MUSK5.45902203
2FRK5.34492614
3WNK35.20074863
4STK394.23420416
5PNCK3.56162573
6SIK23.52062927
7CASK3.10373255
8TNIK2.70821315
9OXSR12.67493730
10BCR2.46783557
11PHKG12.42790004
12PHKG22.42790004
13STK162.32778398
14PKN12.17566116
15IRAK22.08900027
16MAP4K21.98240522
17NEK21.91466788
18IRAK11.82185625
19MAPK131.76117518
20FGR1.73908978
21BMPR1B1.67986724
22WNK41.67795261
23GRK71.57839496
24NTRK31.56449018
25CSNK1G31.48808507
26MAPK151.47908683
27EPHA21.43881173
28WNK11.42969708
29MARK11.40770027
30MAPKAPK31.40553027
31MST41.32789998
32EPHB11.32410842
33ARAF1.31033452
34IRAK41.26591793
35CSNK1A1L1.25802657
36PINK11.25749336
37EPHA41.25679901
38MAPKAPK51.23423689
39MAP3K131.20939618
40UHMK11.17262666
41CSNK1G11.17006510
42ADRBK21.10683324
43PRKD31.09147417
44CSNK1G21.08065562
45NEK61.06034148
46CAMK2B1.04137843
47MAP3K91.02722400
48CAMK2A1.00798802
49NTRK11.00774098
50GRK51.00352217
51NME10.99556388
52CLK10.98955798
53PBK0.97078793
54ROCK20.94957948
55FES0.93531245
56ERBB20.91150890
57MET0.87613774
58PRKCQ0.86911788
59CAMK2D0.86069487
60BRSK20.85571464
61PRPF4B0.82348919
62ACVR1B0.82320825
63TLK10.81428617
64PRKCE0.80343334
65NUAK10.79564256
66PLK10.79434922
67STK380.78821043
68TTK0.77528239
69NTRK20.75465048
70GRK10.75349574
71SGK4940.73457146
72SGK2230.73457146
73AURKA0.73226885
74MKNK20.72534830
75DYRK1A0.72263915
76CDK190.72041417
77DYRK20.71402992
78BUB10.68297246
79CDK50.68039652
80MKNK10.67470741
81PRKCI0.67358104
82PLK40.67084979
83ZAK0.66417435
84PLK20.66167439
85BRAF0.65932692
86FGFR20.65435406
87EPHA30.65340319
88PRKCG0.65220428
89STK110.64710275
90PTK2B0.64268354
91TRIM280.63943223
92CAMK2G0.63752630
93MINK10.62874186
94ICK0.62621694
95BMPR20.62149599
96WEE10.61887297
97PAK30.61379328
98PRKAA20.60336293
99PRKG10.57221813
100PRKACA0.50817203
101CAMK1G0.50779729
102SGK10.49490973
103INSRR0.49186462
104TSSK60.48991229
105PDPK10.48479224
106ABL20.46661186
107PAK60.46290796
108FYN0.46142679
109MAP3K40.46075608
110TGFBR10.45960064
111MAP3K20.45610239
112RIPK40.45472145
113MAP2K20.45426150
114MAP2K70.45069171
115STK38L0.44820787
116CSNK1A10.44599577
117FER0.44553895
118ERBB40.44524782
119PRKD20.44125899
120CDK140.42705052
121CDK150.41128222
122TRPM70.40852912
123ROCK10.39642889
124OBSCN0.39619719
125CDK180.39424553
126TAOK30.38939254
127DDR20.38490275
128ATM0.37975871
129CSNK1E0.36465695
130STK40.36030980
131ERBB30.35800040
132LIMK10.35657991
133CAMKK20.35008344
134ADRBK10.34642063
135MOS0.34191653
136VRK10.34102533
137PRKCA0.33952829
138MARK20.33286613
139CSNK1D0.33235550
140PLK30.32738148
141SGK20.31261539
142RPS6KA50.30860638
143CCNB10.27595652
144CHEK20.24666436
145STK30.23923018
146AKT20.21856704
147MAP3K120.21577336
148ABL10.21486797
149PRKCZ0.20669219

Predicted pathways (KEGG)

RankGene SetZ-score
1Fatty acid elongation_Homo sapiens_hsa000624.86578914
2Oxidative phosphorylation_Homo sapiens_hsa001903.19221567
3Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.88442486
4Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.69920531
5Terpenoid backbone biosynthesis_Homo sapiens_hsa009002.60276172
6Nicotine addiction_Homo sapiens_hsa050332.50299585
7Parkinsons disease_Homo sapiens_hsa050122.48139318
8Fatty acid biosynthesis_Homo sapiens_hsa000612.43877847
9Alzheimers disease_Homo sapiens_hsa050102.42978588
10Ether lipid metabolism_Homo sapiens_hsa005652.38754005
11Steroid biosynthesis_Homo sapiens_hsa001002.22917855
12Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.21328536
13Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.16778546
14GABAergic synapse_Homo sapiens_hsa047272.09358479
15Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.94873721
16Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.91369823
17Caffeine metabolism_Homo sapiens_hsa002321.88363890
18Primary bile acid biosynthesis_Homo sapiens_hsa001201.83763901
19Huntingtons disease_Homo sapiens_hsa050161.83383724
20Fatty acid metabolism_Homo sapiens_hsa012121.80906599
21Morphine addiction_Homo sapiens_hsa050321.77380092
22Protein export_Homo sapiens_hsa030601.75719816
23Serotonergic synapse_Homo sapiens_hsa047261.74615540
24Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.73163807
25ABC transporters_Homo sapiens_hsa020101.64788592
26Glutamatergic synapse_Homo sapiens_hsa047241.64470530
27Axon guidance_Homo sapiens_hsa043601.61152096
28Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.57380311
29Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.56557822
30beta-Alanine metabolism_Homo sapiens_hsa004101.56116543
31Gastric acid secretion_Homo sapiens_hsa049711.53903608
32Collecting duct acid secretion_Homo sapiens_hsa049661.50801157
33Cardiac muscle contraction_Homo sapiens_hsa042601.46146720
34Basal transcription factors_Homo sapiens_hsa030221.44976303
35Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.44461312
36Non-homologous end-joining_Homo sapiens_hsa034501.43980102
37Nitrogen metabolism_Homo sapiens_hsa009101.43960636
38Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.31248337
39Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.28107713
40Pentose and glucuronate interconversions_Homo sapiens_hsa000401.28094038
41Rheumatoid arthritis_Homo sapiens_hsa053231.27717358
42Long-term depression_Homo sapiens_hsa047301.25290460
43Taste transduction_Homo sapiens_hsa047421.23209714
44Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.22747796
45Phototransduction_Homo sapiens_hsa047441.21298041
46RNA polymerase_Homo sapiens_hsa030201.21174971
47Sphingolipid metabolism_Homo sapiens_hsa006001.15007647
48Tryptophan metabolism_Homo sapiens_hsa003801.13883286
49Fanconi anemia pathway_Homo sapiens_hsa034601.13339640
50Circadian entrainment_Homo sapiens_hsa047131.11550054
51Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.06024658
52Homologous recombination_Homo sapiens_hsa034401.04517055
53Selenocompound metabolism_Homo sapiens_hsa004501.04456174
54Ovarian steroidogenesis_Homo sapiens_hsa049131.02955792
55Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.02640198
56Maturity onset diabetes of the young_Homo sapiens_hsa049501.02590182
57Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.02574986
58Amphetamine addiction_Homo sapiens_hsa050310.97584092
59Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.97433161
60Salivary secretion_Homo sapiens_hsa049700.96476008
61Renin secretion_Homo sapiens_hsa049240.95910265
62Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.93684213
63Cholinergic synapse_Homo sapiens_hsa047250.93295610
64RNA degradation_Homo sapiens_hsa030180.92881634
65Olfactory transduction_Homo sapiens_hsa047400.92600302
66Sulfur relay system_Homo sapiens_hsa041220.90703104
67Propanoate metabolism_Homo sapiens_hsa006400.90407183
68Cocaine addiction_Homo sapiens_hsa050300.89800106
69Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.88332129
70Sulfur metabolism_Homo sapiens_hsa009200.88103049
71Calcium signaling pathway_Homo sapiens_hsa040200.87107929
72Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.82533663
73Vibrio cholerae infection_Homo sapiens_hsa051100.81765008
74Proteasome_Homo sapiens_hsa030500.80617102
75Pyruvate metabolism_Homo sapiens_hsa006200.79118856
76Vascular smooth muscle contraction_Homo sapiens_hsa042700.77853866
77Ribosome_Homo sapiens_hsa030100.75806018
78Arachidonic acid metabolism_Homo sapiens_hsa005900.73566063
79Butanoate metabolism_Homo sapiens_hsa006500.73088619
80Regulation of autophagy_Homo sapiens_hsa041400.71904256
81Histidine metabolism_Homo sapiens_hsa003400.71712413
82Dopaminergic synapse_Homo sapiens_hsa047280.71681769
83Linoleic acid metabolism_Homo sapiens_hsa005910.70154015
84Hedgehog signaling pathway_Homo sapiens_hsa043400.69666757
85Synaptic vesicle cycle_Homo sapiens_hsa047210.69291739
86Folate biosynthesis_Homo sapiens_hsa007900.66516261
87Basal cell carcinoma_Homo sapiens_hsa052170.66289047
88Long-term potentiation_Homo sapiens_hsa047200.65212818
89Fatty acid degradation_Homo sapiens_hsa000710.64770588
90Oxytocin signaling pathway_Homo sapiens_hsa049210.63984893
91Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.62418725
92Nucleotide excision repair_Homo sapiens_hsa034200.61661878
93Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.58799497
94Steroid hormone biosynthesis_Homo sapiens_hsa001400.58257539
95Peroxisome_Homo sapiens_hsa041460.56612769
96alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.55973436
97Tight junction_Homo sapiens_hsa045300.55440375
98Aldosterone synthesis and secretion_Homo sapiens_hsa049250.55303892
99Phagosome_Homo sapiens_hsa041450.54079538
100Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.52895709
101Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.52175087
102Purine metabolism_Homo sapiens_hsa002300.51704974
103ECM-receptor interaction_Homo sapiens_hsa045120.51605921
104Insulin secretion_Homo sapiens_hsa049110.50711167
105Dilated cardiomyopathy_Homo sapiens_hsa054140.50592487
106Mineral absorption_Homo sapiens_hsa049780.50332065
107Tyrosine metabolism_Homo sapiens_hsa003500.49669766
108Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.49603809
109Pancreatic secretion_Homo sapiens_hsa049720.49225856
110Circadian rhythm_Homo sapiens_hsa047100.49192249
111GnRH signaling pathway_Homo sapiens_hsa049120.48133102
112Cysteine and methionine metabolism_Homo sapiens_hsa002700.48039852
113Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.47207461
114Ras signaling pathway_Homo sapiens_hsa040140.46918323
115Prion diseases_Homo sapiens_hsa050200.45904867
116Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.45657993
117cAMP signaling pathway_Homo sapiens_hsa040240.44975078
118Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.44883459
119SNARE interactions in vesicular transport_Homo sapiens_hsa041300.44239060
120Gap junction_Homo sapiens_hsa045400.43539259
121Chemical carcinogenesis_Homo sapiens_hsa052040.43245766
122Drug metabolism - other enzymes_Homo sapiens_hsa009830.43034894
123Glutathione metabolism_Homo sapiens_hsa004800.42758769
124Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.39925698
125Metabolic pathways_Homo sapiens_hsa011000.39590336
126Autoimmune thyroid disease_Homo sapiens_hsa053200.37894586
127Phenylalanine metabolism_Homo sapiens_hsa003600.37372395
128Malaria_Homo sapiens_hsa051440.37262543
129Type I diabetes mellitus_Homo sapiens_hsa049400.37167142
130Vitamin digestion and absorption_Homo sapiens_hsa049770.36679571
131Starch and sucrose metabolism_Homo sapiens_hsa005000.36483009
132Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.35820406
133Retinol metabolism_Homo sapiens_hsa008300.35768363
134PPAR signaling pathway_Homo sapiens_hsa033200.32687284
135One carbon pool by folate_Homo sapiens_hsa006700.32599385
136Pyrimidine metabolism_Homo sapiens_hsa002400.32316333
137Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.32008442
138Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.30948327
139Other glycan degradation_Homo sapiens_hsa005110.30047205
140Graft-versus-host disease_Homo sapiens_hsa053320.25133066
141Sphingolipid signaling pathway_Homo sapiens_hsa040710.24071781
142Arginine and proline metabolism_Homo sapiens_hsa003300.23868381
143Melanogenesis_Homo sapiens_hsa049160.23287143
144African trypanosomiasis_Homo sapiens_hsa051430.23205151

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »