Rank | Gene Set | Z-score |
---|---|---|
1 | L-phenylalanine catabolic process (GO:0006559) | 7.19284289 |
2 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222) | 7.19284289 |
3 | L-phenylalanine metabolic process (GO:0006558) | 6.90346347 |
4 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221) | 6.90346347 |
5 | triglyceride-rich lipoprotein particle remodeling (GO:0034370) | 6.63950875 |
6 | protoporphyrinogen IX metabolic process (GO:0046501) | 6.57516946 |
7 | aromatic amino acid family catabolic process (GO:0009074) | 6.48653594 |
8 | protoporphyrinogen IX biosynthetic process (GO:0006782) | 6.01319852 |
9 | indole-containing compound catabolic process (GO:0042436) | 5.86727415 |
10 | indolalkylamine catabolic process (GO:0046218) | 5.86727415 |
11 | tryptophan catabolic process (GO:0006569) | 5.86727415 |
12 | kynurenine metabolic process (GO:0070189) | 5.75959999 |
13 | high-density lipoprotein particle remodeling (GO:0034375) | 5.68888780 |
14 | alpha-linolenic acid metabolic process (GO:0036109) | 5.68338297 |
15 | bile acid biosynthetic process (GO:0006699) | 5.60097056 |
16 | tryptophan metabolic process (GO:0006568) | 5.52345880 |
17 | urea cycle (GO:0000050) | 5.50402329 |
18 | urea metabolic process (GO:0019627) | 5.50402329 |
19 | glyoxylate metabolic process (GO:0046487) | 5.47105259 |
20 | epoxygenase P450 pathway (GO:0019373) | 5.45560341 |
21 | negative regulation of fibrinolysis (GO:0051918) | 5.31587468 |
22 | cysteine metabolic process (GO:0006534) | 5.27736562 |
23 | regulation of cholesterol esterification (GO:0010872) | 5.19700624 |
24 | exogenous drug catabolic process (GO:0042738) | 5.11265830 |
25 | proline metabolic process (GO:0006560) | 5.10553593 |
26 | regulation of fibrinolysis (GO:0051917) | 5.09548847 |
27 | sulfur amino acid catabolic process (GO:0000098) | 5.09351898 |
28 | peptidyl-glutamic acid carboxylation (GO:0017187) | 5.08672777 |
29 | protein carboxylation (GO:0018214) | 5.08672777 |
30 | nitrogen cycle metabolic process (GO:0071941) | 5.06068134 |
31 | regulation of triglyceride catabolic process (GO:0010896) | 5.05175881 |
32 | reverse cholesterol transport (GO:0043691) | 5.04183871 |
33 | phospholipid efflux (GO:0033700) | 4.97597921 |
34 | regulation of protein activation cascade (GO:2000257) | 4.94031525 |
35 | bile acid metabolic process (GO:0008206) | 4.91439438 |
36 | plasma lipoprotein particle remodeling (GO:0034369) | 4.89688696 |
37 | protein-lipid complex remodeling (GO:0034368) | 4.89688696 |
38 | macromolecular complex remodeling (GO:0034367) | 4.89688696 |
39 | serine family amino acid catabolic process (GO:0009071) | 4.87193417 |
40 | complement activation, alternative pathway (GO:0006957) | 4.85998648 |
41 | negative regulation of cholesterol transport (GO:0032375) | 4.77704054 |
42 | negative regulation of sterol transport (GO:0032372) | 4.77704054 |
43 | fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540) | 4.75909383 |
44 | aromatic amino acid family metabolic process (GO:0009072) | 4.70819199 |
45 | lysine catabolic process (GO:0006554) | 4.70783492 |
46 | lysine metabolic process (GO:0006553) | 4.70783492 |
47 | acylglycerol homeostasis (GO:0055090) | 4.65049475 |
48 | triglyceride homeostasis (GO:0070328) | 4.65049475 |
49 | regulation of complement activation (GO:0030449) | 4.59807206 |
50 | omega-hydroxylase P450 pathway (GO:0097267) | 4.59409830 |
51 | homocysteine metabolic process (GO:0050667) | 4.59323469 |
52 | amino-acid betaine metabolic process (GO:0006577) | 4.51996225 |
53 | bile acid and bile salt transport (GO:0015721) | 4.50937699 |
54 | plasma lipoprotein particle assembly (GO:0034377) | 4.50082361 |
55 | tyrosine metabolic process (GO:0006570) | 4.49272631 |
56 | cholesterol efflux (GO:0033344) | 4.48523386 |
57 | cellular ketone body metabolic process (GO:0046950) | 4.47965203 |
58 | negative regulation of fatty acid biosynthetic process (GO:0045717) | 4.43941885 |
59 | alpha-amino acid catabolic process (GO:1901606) | 4.43822688 |
60 | plasma lipoprotein particle clearance (GO:0034381) | 4.42733011 |
61 | porphyrin-containing compound metabolic process (GO:0006778) | 4.33533182 |
62 | cellular glucuronidation (GO:0052695) | 4.29411947 |
63 | glycine metabolic process (GO:0006544) | 4.27239063 |
64 | regulation of plasminogen activation (GO:0010755) | 4.26903347 |
65 | proline biosynthetic process (GO:0006561) | 4.22968290 |
66 | very-low-density lipoprotein particle assembly (GO:0034379) | 4.21968426 |
67 | drug catabolic process (GO:0042737) | 4.19420670 |
68 | oxaloacetate metabolic process (GO:0006107) | 4.19030185 |
69 | porphyrin-containing compound biosynthetic process (GO:0006779) | 4.16681798 |
70 | positive regulation of lipoprotein lipase activity (GO:0051006) | 4.16368079 |
71 | positive regulation of triglyceride lipase activity (GO:0061365) | 4.16368079 |
72 | intestinal cholesterol absorption (GO:0030299) | 4.15384851 |
73 | glutamate metabolic process (GO:0006536) | 4.15019691 |
74 | indolalkylamine metabolic process (GO:0006586) | 4.14595958 |
75 | ethanol oxidation (GO:0006069) | 4.14043080 |
76 | imidazole-containing compound metabolic process (GO:0052803) | 4.13838927 |
77 | ethanol metabolic process (GO:0006067) | 4.10451780 |
78 | serine family amino acid metabolic process (GO:0009069) | 4.09059667 |
79 | coenzyme catabolic process (GO:0009109) | 4.08499475 |
80 | cellular amino acid catabolic process (GO:0009063) | 4.08492628 |
81 | amine catabolic process (GO:0009310) | 4.06122800 |
82 | cellular biogenic amine catabolic process (GO:0042402) | 4.06122800 |
83 | heme metabolic process (GO:0042168) | 4.05012470 |
84 | protein-lipid complex assembly (GO:0065005) | 4.04409711 |
85 | benzene-containing compound metabolic process (GO:0042537) | 4.02905641 |
86 | drug metabolic process (GO:0017144) | 4.02064940 |
87 | erythrocyte maturation (GO:0043249) | 3.98459354 |
88 | low-density lipoprotein particle remodeling (GO:0034374) | 3.95101076 |
89 | cellular modified amino acid catabolic process (GO:0042219) | 3.92392409 |
90 | cholesterol homeostasis (GO:0042632) | 3.91415068 |
91 | arginine metabolic process (GO:0006525) | 3.90261520 |
92 | serine family amino acid biosynthetic process (GO:0009070) | 3.90032421 |
93 | plasma lipoprotein particle organization (GO:0071827) | 3.88140997 |
94 | ketone body metabolic process (GO:1902224) | 3.87205679 |
95 | dicarboxylic acid biosynthetic process (GO:0043650) | 3.86430205 |
96 | negative regulation of erythrocyte differentiation (GO:0045647) | 3.86075603 |
97 | phospholipid homeostasis (GO:0055091) | 3.85468544 |
98 | sterol homeostasis (GO:0055092) | 3.85344358 |
99 | positive regulation of lipid catabolic process (GO:0050996) | 3.84594560 |
100 | glucuronate metabolic process (GO:0019585) | 3.81035196 |
101 | uronic acid metabolic process (GO:0006063) | 3.81035196 |
102 | regulation of bile acid biosynthetic process (GO:0070857) | 3.80282627 |
103 | negative regulation of blood coagulation (GO:0030195) | 3.79443608 |
104 | negative regulation of hemostasis (GO:1900047) | 3.79443608 |
105 | regulation of cholesterol homeostasis (GO:2000188) | 3.77776116 |
106 | flavonoid metabolic process (GO:0009812) | 3.77281663 |
107 | fibrinolysis (GO:0042730) | 3.77250674 |
108 | aldehyde catabolic process (GO:0046185) | 3.74326751 |
109 | blood coagulation, intrinsic pathway (GO:0007597) | 3.73016821 |
110 | heme biosynthetic process (GO:0006783) | 3.72963301 |
111 | cofactor catabolic process (GO:0051187) | 3.71744217 |
112 | lipoprotein metabolic process (GO:0042157) | 3.69885888 |
113 | short-chain fatty acid metabolic process (GO:0046459) | 3.69499274 |
114 | phenylpropanoid metabolic process (GO:0009698) | 3.68567523 |
115 | response to nitrosative stress (GO:0051409) | 3.67175064 |
116 | heme transport (GO:0015886) | 3.66575477 |
117 | tetrapyrrole biosynthetic process (GO:0033014) | 3.66536399 |
118 | oxidative demethylation (GO:0070989) | 3.66236131 |
119 | S-adenosylmethionine metabolic process (GO:0046500) | 3.65705629 |
120 | protein-lipid complex subunit organization (GO:0071825) | 3.65617610 |
121 | negative regulation of lipase activity (GO:0060192) | 3.63841705 |
122 | acetyl-CoA metabolic process (GO:0006084) | 3.60741229 |
123 | carboxylic acid catabolic process (GO:0046395) | 3.60191772 |
124 | organic acid catabolic process (GO:0016054) | 3.60191772 |
125 | tetrahydrofolate metabolic process (GO:0046653) | 3.56045652 |
126 | protein activation cascade (GO:0072376) | 3.54898940 |
127 | regulation of lipoprotein particle clearance (GO:0010984) | 3.54165685 |
128 | oxygen transport (GO:0015671) | 3.53549084 |
129 | gas transport (GO:0015669) | 3.49785000 |
130 | positive regulation of blood coagulation (GO:0030194) | 3.40914217 |
131 | positive regulation of hemostasis (GO:1900048) | 3.40914217 |
132 | acute-phase response (GO:0006953) | 3.40763263 |
133 | regulation of apoptotic cell clearance (GO:2000425) | 3.39153473 |
134 | negative regulation of coagulation (GO:0050819) | 3.35761748 |
135 | glutamine family amino acid biosynthetic process (GO:0009084) | 3.35617716 |
136 | hemoglobin metabolic process (GO:0020027) | 3.31015418 |
137 | negative regulation of wound healing (GO:0061045) | 3.27303999 |
138 | regulation of fatty acid biosynthetic process (GO:0042304) | 3.23063539 |
139 | positive regulation of fatty acid biosynthetic process (GO:0045723) | 3.17802418 |
Rank | Gene Set | Z-score |
---|---|---|
1 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 8.30200480 |
2 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 7.23122284 |
3 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 6.89025041 |
4 | E2F7_22180533_ChIP-Seq_HELA_Human | 6.54245769 |
5 | LXR_22158963_ChIP-Seq_LIVER_Mouse | 6.44961779 |
6 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 5.10136476 |
7 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 5.08743801 |
8 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 4.92538529 |
9 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 3.98142778 |
10 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 3.97767649 |
11 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 3.32582318 |
12 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 2.33965549 |
13 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 2.32084461 |
14 | NCOR1_26117541_ChIP-Seq_K562_Human | 2.22153561 |
15 | TCF7L2_21901280_ChIP-Seq_H4IIE_Rat | 2.06306408 |
16 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.05953624 |
17 | GATA1_22025678_ChIP-Seq_K562_Human | 2.04057225 |
18 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.00237833 |
19 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 11.8572919 |
20 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.96702967 |
21 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.80238041 |
22 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.79914799 |
23 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.73518952 |
24 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.62539106 |
25 | FOXA2_19822575_ChIP-Seq_HepG2_Human | 1.60675764 |
26 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.60308389 |
27 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.60297506 |
28 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.54644548 |
29 | MYC_22102868_ChIP-Seq_BL_Human | 1.51982666 |
30 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 1.50799271 |
31 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.50099317 |
32 | * HNF4A_19822575_ChIP-Seq_HepG2_Human | 1.47858997 |
33 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.46073593 |
34 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.42019818 |
35 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.40062719 |
36 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.34169081 |
37 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.33629064 |
38 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.32906604 |
39 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.32798310 |
40 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.32211934 |
41 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.28607485 |
42 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.28265503 |
43 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.27940305 |
44 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.27152648 |
45 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.26397401 |
46 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.24664951 |
47 | SOX2_27498859_Chip-Seq_STOMACH_Mouse | 1.24591600 |
48 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.20394727 |
49 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.20237912 |
50 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.19159089 |
51 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.17792001 |
52 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.17374352 |
53 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.16626183 |
54 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.16611988 |
55 | RXRA_24833708_ChIP-Seq_LIVER_Mouse | 1.14364245 |
56 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 1.12819081 |
57 | GATA4_25053715_ChIP-Seq_YYC3_Human | 1.09790091 |
58 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 1.08680160 |
59 | * ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.08528409 |
60 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.08202448 |
61 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.08157458 |
62 | ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.05453248 |
63 | * E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.05112661 |
64 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.03973600 |
65 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.03316811 |
66 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.02580078 |
67 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.02212633 |
68 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.01973147 |
69 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 0.99545361 |
70 | ZNF263_19887448_ChIP-Seq_K562_Human | 0.95775273 |
71 | GATA1_19941826_ChIP-Seq_K562_Human | 0.94795148 |
72 | KDM5A_27292631_Chip-Seq_BREAST_Human | 0.93774545 |
73 | P68_20966046_ChIP-Seq_HELA_Human | 0.92491067 |
74 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 0.92428457 |
75 | TTF2_22483619_ChIP-Seq_HELA_Human | 0.92112569 |
76 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 0.91127912 |
77 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 0.89635369 |
78 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 0.88756261 |
79 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 0.86738503 |
80 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 0.86128916 |
81 | GABP_19822575_ChIP-Seq_HepG2_Human | 0.85995129 |
82 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 0.85739086 |
83 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 0.85562713 |
84 | SREBP1_19666523_ChIP-Seq_LIVER_Mouse | 0.85173388 |
85 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 0.85097239 |
86 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 0.85008767 |
87 | PHF8_20622854_ChIP-Seq_HELA_Human | 0.84988993 |
88 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 0.84419535 |
89 | * GATA1_19941827_ChIP-Seq_MEL_Mouse | 0.83948716 |
90 | SREBP2_21459322_ChIP-Seq_LIVER_Mouse | 0.83904507 |
91 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.82137845 |
92 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 0.81837902 |
93 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 0.81668380 |
94 | E2F1_20622854_ChIP-Seq_HELA_Human | 0.81633770 |
95 | RARA_24833708_ChIP-Seq_LIVER_Mouse | 0.81378643 |
96 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 0.81197778 |
97 | SPI1_23127762_ChIP-Seq_K562_Human | 0.79348766 |
98 | CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.78905293 |
99 | CIITA_25753668_ChIP-Seq_RAJI_Human | 0.78732508 |
100 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.78549719 |
101 | TBX5_21415370_ChIP-Seq_HL-1_Mouse | 0.77932618 |
102 | KAP1_22055183_ChIP-Seq_ESCs_Mouse | 0.75958055 |
103 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 0.75341633 |
104 | GATA2_19941826_ChIP-Seq_K562_Human | 0.75300775 |
105 | CDX2_20551321_ChIP-Seq_CACO-2_Human | 0.75276185 |
106 | NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 0.74985326 |
107 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 0.74747588 |
108 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 0.73121453 |
109 | AR_21915096_ChIP-Seq_LNCaP-1F5_Human | 0.72765292 |
110 | SALL4_18804426_ChIP-ChIP_XEN_Mouse | 0.72353878 |
111 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 0.71080177 |
112 | GATA6_25053715_ChIP-Seq_YYC3_Human | 0.69472445 |
113 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 0.67058501 |
114 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 0.65740683 |
115 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 0.65089157 |
116 | RARB_24833708_ChIP-Seq_LIVER_Mouse | 0.64806708 |
117 | RAD21_21589869_ChIP-Seq_MESCs_Mouse | 0.62809477 |
118 | BMI1_19503595_ChIP-Seq_MEFsC_Mouse | 0.62239890 |
119 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 0.62169692 |
120 | * LXR_22292898_ChIP-Seq_THP-1_Human | 0.60925262 |
121 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 0.59961225 |
122 | CEBPB_22108803_ChIP-Seq_LS180_Human | 0.59820155 |
123 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 0.57181198 |
124 | FOXA1_25552417_ChIP-Seq_VCAP_Human | 0.55966569 |
125 | FOXA1_26743006_Chip-Seq_LNCaP-abl_Human | 0.55798746 |
126 | FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.54755761 |
127 | AR_20517297_ChIP-Seq_VCAP_Human | 0.54189377 |
128 | EGR1_19032775_ChIP-ChIP_M12_Human | 0.54030784 |
129 | FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human | 0.53842815 |
130 | * MYC_19915707_ChIP-ChIP_AK7_Human | 0.51326768 |
131 | * TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 0.50847963 |
132 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 0.49760838 |
133 | PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 0.49426768 |
134 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 0.48101408 |
135 | P53_21459846_ChIP-Seq_SAOS-2_Human | 0.47847711 |
136 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 0.47400018 |
137 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 0.47400018 |
138 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.46533295 |
139 | STAT1_17558387_ChIP-Seq_HELA_Human | 0.46523701 |
140 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 0.46360736 |
141 | ESET_19884257_ChIP-Seq_ESCs_Mouse | 0.46209364 |
142 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.45336266 |
143 | CBP_21632823_ChIP-Seq_H3396_Human | 0.42896753 |
144 | SOX2_20726797_ChIP-Seq_SW620_Human | 0.42866358 |
145 | SMAD2/3_21741376_ChIP-Seq_ESCs_Human | 0.42196330 |
146 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 0.41712552 |
147 | PPARG_20887899_ChIP-Seq_3T3-L1_Mouse | 0.41371964 |
148 | SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 0.41358998 |
149 | BCOR_27268052_Chip-Seq_Bcells_Human | 0.41137874 |
150 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 0.40822034 |
151 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.38724634 |
152 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 0.38049079 |
153 | GATA3_20176728_ChIP-ChIP_TSCs_Mouse | 0.37733266 |
154 | RACK7_27058665_Chip-Seq_MCF-7_Human | 0.37465903 |
155 | SPI1_26923725_Chip-Seq_HPCs_Mouse | 0.37279239 |
156 | ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.37179385 |
157 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 0.36707025 |
158 | SOX3_22085726_ChIP-Seq_MUSCLE_Mouse | 0.36122358 |
159 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 0.36100661 |
160 | KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse | 0.35871407 |
161 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 0.35758452 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0002139_abnormal_hepatobiliary_system | 8.29713429 |
2 | MP0005360_urolithiasis | 7.91017402 |
3 | MP0005085_abnormal_gallbladder_physiolo | 6.28568225 |
4 | MP0005365_abnormal_bile_salt | 5.89505474 |
5 | MP0008875_abnormal_xenobiotic_pharmacok | 4.99979745 |
6 | MP0003806_abnormal_nucleotide_metabolis | 4.18287050 |
7 | MP0003252_abnormal_bile_duct | 3.90755083 |
8 | MP0010329_abnormal_lipoprotein_level | 3.62464947 |
9 | MP0009840_abnormal_foam_cell | 3.52971188 |
10 | MP0005083_abnormal_biliary_tract | 3.12639258 |
11 | MP0001666_abnormal_nutrient_absorption | 2.98602962 |
12 | MP0005332_abnormal_amino_acid | 2.66251905 |
13 | MP0003195_calcinosis | 2.58392988 |
14 | MP0003191_abnormal_cellular_cholesterol | 2.25325101 |
15 | MP0004019_abnormal_vitamin_homeostasis | 2.19525184 |
16 | MP0000609_abnormal_liver_physiology | 2.17041111 |
17 | MP0003656_abnormal_erythrocyte_physiolo | 2.09400100 |
18 | MP0002118_abnormal_lipid_homeostasis | 2.07341377 |
19 | MP0001545_abnormal_hematopoietic_system | 1.96573968 |
20 | MP0005397_hematopoietic_system_phenotyp | 1.96573968 |
21 | MP0002138_abnormal_hepatobiliary_system | 1.87654159 |
22 | MP0003868_abnormal_feces_composition | 1.86098150 |
23 | MP0005319_abnormal_enzyme/_coenzyme | 1.78599354 |
24 | MP0003111_abnormal_nucleus_morphology | 1.64948205 |
25 | MP0001764_abnormal_homeostasis | 1.62918011 |
26 | MP0009697_abnormal_copulation | 1.62622177 |
27 | MP0005584_abnormal_enzyme/coenzyme_acti | 1.52371992 |
28 | MP0008995_early_reproductive_senescence | 1.42361134 |
29 | MP0004145_abnormal_muscle_electrophysio | 1.37788255 |
30 | MP0005451_abnormal_body_composition | 1.36123864 |
31 | MP0009643_abnormal_urine_homeostasis | 1.32796480 |
32 | MP0000678_abnormal_parathyroid_gland | 1.29498841 |
33 | MP0003011_delayed_dark_adaptation | 1.25262436 |
34 | MP0003186_abnormal_redox_activity | 1.24562771 |
35 | MP0004957_abnormal_blastocyst_morpholog | 1.19162850 |
36 | MP0000598_abnormal_liver_morphology | 1.17332184 |
37 | MP0005636_abnormal_mineral_homeostasis | 1.15763628 |
38 | MP0004147_increased_porphyrin_level | 1.15541044 |
39 | MP0003705_abnormal_hypodermis_morpholog | 1.14034009 |
40 | MP0003693_abnormal_embryo_hatching | 1.06550122 |
41 | MP0010094_abnormal_chromosome_stability | 1.03717435 |
42 | MP0000604_amyloidosis | 1.01179732 |
43 | MP0002396_abnormal_hematopoietic_system | 1.01103611 |
44 | MP0009764_decreased_sensitivity_to | 1.00540248 |
45 | MP0005647_abnormal_sex_gland | 1.00224619 |
46 | MP0000566_synostosis | 0.99472680 |
47 | MP0009763_increased_sensitivity_to | 0.96297546 |
48 | MP0002254_reproductive_system_inflammat | 0.93926517 |
49 | MP0006036_abnormal_mitochondrial_physio | 0.91001762 |
50 | MP0005058_abnormal_lysosome_morphology | 0.88565571 |
51 | MP0005084_abnormal_gallbladder_morpholo | 0.88288267 |
52 | MP0009642_abnormal_blood_homeostasis | 0.87957593 |
53 | MP0001915_intracranial_hemorrhage | 0.86442291 |
54 | MP0008058_abnormal_DNA_repair | 0.86058522 |
55 | MP0008469_abnormal_protein_level | 0.85611820 |
56 | MP0001730_embryonic_growth_arrest | 0.83876969 |
57 | MP0005408_hypopigmentation | 0.80736023 |
58 | MP0009765_abnormal_xenobiotic_induced | 0.79667073 |
59 | MP0005376_homeostasis/metabolism_phenot | 0.79233889 |
60 | MP0002078_abnormal_glucose_homeostasis | 0.79025193 |
61 | MP0002876_abnormal_thyroid_physiology | 0.77047028 |
62 | MP0010368_abnormal_lymphatic_system | 0.74955272 |
63 | MP0003172_abnormal_lysosome_physiology | 0.73538884 |
64 | MP0008775_abnormal_heart_ventricle | 0.71414933 |
65 | MP0005334_abnormal_fat_pad | 0.69934085 |
66 | MP0002971_abnormal_brown_adipose | 0.68723121 |
67 | MP0005266_abnormal_metabolism | 0.68508717 |
68 | MP0003077_abnormal_cell_cycle | 0.68100240 |
69 | MP0009053_abnormal_anal_canal | 0.67904177 |
70 | MP0003959_abnormal_lean_body | 0.67617516 |
71 | MP0005220_abnormal_exocrine_pancreas | 0.67416078 |
72 | MP0005448_abnormal_energy_balance | 0.65971406 |
73 | MP0001756_abnormal_urination | 0.64325742 |
74 | MP0009931_abnormal_skin_appearance | 0.62756054 |
75 | MP0008932_abnormal_embryonic_tissue | 0.62700774 |
76 | MP0008007_abnormal_cellular_replicative | 0.61179447 |
77 | MP0005670_abnormal_white_adipose | 0.61115056 |
78 | MP0005464_abnormal_platelet_physiology | 0.60608858 |
79 | MP0005535_abnormal_body_temperature | 0.60299554 |
80 | MP0001697_abnormal_embryo_size | 0.60174420 |
81 | MP0002822_catalepsy | 0.59848693 |
82 | MP0003329_amyloid_beta_deposits | 0.59584101 |
83 | MP0002086_abnormal_extraembryonic_tissu | 0.59444166 |
84 | MP0008057_abnormal_DNA_replication | 0.59064075 |
85 | MP0002080_prenatal_lethality | 0.56597330 |
86 | MP0002249_abnormal_larynx_morphology | 0.56575710 |
87 | MP0002089_abnormal_postnatal_growth/wei | 0.56543190 |
88 | MP0003718_maternal_effect | 0.56468484 |
89 | MP0004264_abnormal_extraembryonic_tissu | 0.56354863 |
90 | MP0003879_abnormal_hair_cell | 0.56059095 |
91 | MP0004130_abnormal_muscle_cell | 0.55888860 |
92 | MP0006035_abnormal_mitochondrial_morpho | 0.55302902 |
93 | MP0001661_extended_life_span | 0.54541443 |
94 | MP0009278_abnormal_bone_marrow | 0.52552362 |
95 | MP0002136_abnormal_kidney_physiology | 0.51889798 |
96 | MP0009333_abnormal_splenocyte_physiolog | 0.51370052 |
97 | MP0000313_abnormal_cell_death | 0.50659326 |
98 | MP0003690_abnormal_glial_cell | 0.49987864 |
99 | MP0000639_abnormal_adrenal_gland | 0.49873808 |
100 | MP0008872_abnormal_physiological_respon | 0.49160485 |
101 | MP0003699_abnormal_female_reproductive | 0.48867766 |
102 | MP0008873_increased_physiological_sensi | 0.46263115 |
103 | MP0005076_abnormal_cell_differentiation | 0.46174653 |
104 | MP0003984_embryonic_growth_retardation | 0.44900280 |
105 | MP0005395_other_phenotype | 0.44657217 |
106 | MP0003786_premature_aging | 0.44462252 |
107 | MP0003638_abnormal_response/metabolism_ | 0.43594358 |
108 | MP0005187_abnormal_penis_morphology | 0.42905166 |
109 | MP0004233_abnormal_muscle_weight | 0.42122731 |
110 | MP0003953_abnormal_hormone_level | 0.42095958 |
111 | MP0002088_abnormal_embryonic_growth/wei | 0.42019826 |
112 | MP0004043_abnormal_pH_regulation | 0.41892605 |
113 | MP0001672_abnormal_embryogenesis/_devel | 0.41819731 |
114 | MP0005380_embryogenesis_phenotype | 0.41819731 |
115 | MP0003567_abnormal_fetal_cardiomyocyte | 0.41785486 |
116 | MP0005410_abnormal_fertilization | 0.41085035 |
117 | MP0000350_abnormal_cell_proliferation | 0.39891095 |
118 | MP0002796_impaired_skin_barrier | 0.39103667 |
119 | MP0002928_abnormal_bile_duct | 0.37482831 |
120 | MP0009115_abnormal_fat_cell | 0.35882179 |
121 | MP0005666_abnormal_adipose_tissue | 0.35793457 |
122 | MP0004782_abnormal_surfactant_physiolog | 0.35711819 |
123 | MP0009672_abnormal_birth_weight | 0.35271660 |
124 | MP0005166_decreased_susceptibility_to | 0.35147028 |
125 | MP0008874_decreased_physiological_sensi | 0.34887729 |
126 | MP0010234_abnormal_vibrissa_follicle | 0.34821850 |
127 | MP0002132_abnormal_respiratory_system | 0.34721455 |
128 | MP0003075_altered_response_to | 0.34539753 |
129 | MP0001243_abnormal_dermal_layer | 0.34065695 |
130 | MP0002970_abnormal_white_adipose | 0.33030499 |
131 | MP0003436_decreased_susceptibility_to | 0.32682855 |
132 | MP0003300_gastrointestinal_ulcer | 0.32062302 |
133 | MP0003724_increased_susceptibility_to | 0.31782267 |
134 | MP0000230_abnormal_systemic_arterial | 0.29914844 |
135 | MP0001845_abnormal_inflammatory_respons | 0.29094767 |
136 | MP0000249_abnormal_blood_vessel | 0.28416161 |
137 | MP0001881_abnormal_mammary_gland | 0.28317140 |
138 | MP0005248_abnormal_Harderian_gland | 0.28306913 |
139 | MP0002837_dystrophic_cardiac_calcinosis | 0.27604482 |
140 | MP0001765_abnormal_ion_homeostasis | 0.26202553 |
141 | MP0000579_abnormal_nail_morphology | 0.24918442 |
142 | MP0006082_CNS_inflammation | 0.24502589 |
143 | MP0001853_heart_inflammation | 0.24372855 |
144 | MP0005167_abnormal_blood-brain_barrier | 0.24048364 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Deep venous thrombosis (HP:0002625) | 7.04094966 |
2 | Intrahepatic cholestasis (HP:0001406) | 7.00695108 |
3 | Abnormality of aromatic amino acid family metabolism (HP:0004338) | 7.00443778 |
4 | Hypobetalipoproteinemia (HP:0003563) | 6.72470278 |
5 | Abnormality of monocarboxylic acid metabolism (HP:0010996) | 6.50674415 |
6 | Prolonged partial thromboplastin time (HP:0003645) | 6.20665834 |
7 | Xanthomatosis (HP:0000991) | 6.15934544 |
8 | Hyperlipoproteinemia (HP:0010980) | 5.19735216 |
9 | Hypolipoproteinemia (HP:0010981) | 4.90091747 |
10 | Complement deficiency (HP:0004431) | 4.77696267 |
11 | Hyperammonemia (HP:0001987) | 4.51458296 |
12 | Joint hemorrhage (HP:0005261) | 4.50525630 |
13 | Abnormality of glutamine family amino acid metabolism (HP:0010902) | 4.42317663 |
14 | Abnormality of the level of lipoprotein cholesterol (HP:0010979) | 4.40909148 |
15 | Epidermoid cyst (HP:0200040) | 4.28582234 |
16 | Hyperglycinemia (HP:0002154) | 4.22008419 |
17 | Abnormality of the common coagulation pathway (HP:0010990) | 4.19756630 |
18 | Abnormality of sulfur amino acid metabolism (HP:0004339) | 4.17650454 |
19 | Fat malabsorption (HP:0002630) | 4.17634351 |
20 | Ketosis (HP:0001946) | 4.15017510 |
21 | * Cholecystitis (HP:0001082) | 4.14134511 |
22 | * Abnormal gallbladder physiology (HP:0012438) | 4.14134511 |
23 | Hypoalphalipoproteinemia (HP:0003233) | 4.07198688 |
24 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 4.06691859 |
25 | * Abnormality of reticulocytes (HP:0004312) | 4.04865290 |
26 | Hypoglycemic coma (HP:0001325) | 4.01398911 |
27 | Hyperglycinuria (HP:0003108) | 3.98039392 |
28 | Abnormality of methionine metabolism (HP:0010901) | 3.96373481 |
29 | Acanthocytosis (HP:0001927) | 3.93623699 |
30 | Abnormality of glycine metabolism (HP:0010895) | 3.90002464 |
31 | Abnormality of serine family amino acid metabolism (HP:0010894) | 3.90002464 |
32 | Conjugated hyperbilirubinemia (HP:0002908) | 3.88523897 |
33 | Abnormality of pyrimidine metabolism (HP:0004353) | 3.75750879 |
34 | * Hyperbilirubinemia (HP:0002904) | 3.63993986 |
35 | Hypercholesterolemia (HP:0003124) | 3.63697271 |
36 | Abnormality of the intrinsic pathway (HP:0010989) | 3.63156422 |
37 | Hypochromic microcytic anemia (HP:0004840) | 3.53127692 |
38 | Abnormality of complement system (HP:0005339) | 3.49226257 |
39 | * Polycythemia (HP:0001901) | 3.46513722 |
40 | Abnormal hemoglobin (HP:0011902) | 3.46013255 |
41 | Poikilocytosis (HP:0004447) | 3.40186581 |
42 | Abnormality of long-chain fatty-acid metabolism (HP:0010964) | 3.32868676 |
43 | Abnormality of fatty-acid metabolism (HP:0004359) | 3.29240662 |
44 | Abnormality of nucleobase metabolism (HP:0010932) | 3.17693061 |
45 | Hepatocellular carcinoma (HP:0001402) | 3.15111876 |
46 | Ketoacidosis (HP:0001993) | 3.06191755 |
47 | Osteomalacia (HP:0002749) | 3.01691512 |
48 | Steatorrhea (HP:0002570) | 2.97031217 |
49 | Metabolic acidosis (HP:0001942) | 2.95782147 |
50 | Delayed CNS myelination (HP:0002188) | 2.93669115 |
51 | Abnormality of serum amino acid levels (HP:0003112) | 2.88711280 |
52 | Abnormality of purine metabolism (HP:0004352) | 2.88664152 |
53 | Increased serum ferritin (HP:0003281) | 2.79387322 |
54 | Increased serum pyruvate (HP:0003542) | 2.74410056 |
55 | Spontaneous abortion (HP:0005268) | 2.72570839 |
56 | Myocardial infarction (HP:0001658) | 2.71648979 |
57 | Truncus arteriosus (HP:0001660) | 2.70285016 |
58 | Seborrheic dermatitis (HP:0001051) | 2.68736372 |
59 | Abnormality of glycolysis (HP:0004366) | 2.67288303 |
60 | Hypoglycemic seizures (HP:0002173) | 2.66352331 |
61 | Malnutrition (HP:0004395) | 2.66295941 |
62 | Skin nodule (HP:0200036) | 2.60788967 |
63 | * Abnormal gallbladder morphology (HP:0012437) | 2.59288740 |
64 | Lethargy (HP:0001254) | 2.58112610 |
65 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 2.57751952 |
66 | Dicarboxylic aciduria (HP:0003215) | 2.57751952 |
67 | Vascular calcification (HP:0004934) | 2.53740151 |
68 | * Cholelithiasis (HP:0001081) | 2.51476607 |
69 | Systemic lupus erythematosus (HP:0002725) | 2.48204281 |
70 | Gout (HP:0001997) | 2.46541345 |
71 | Impaired platelet aggregation (HP:0003540) | 2.45441441 |
72 | Abnormal platelet function (HP:0011869) | 2.45441441 |
73 | Paralysis (HP:0003470) | 2.44776398 |
74 | Hyperthyroidism (HP:0000836) | 2.41884484 |
75 | Cerebral palsy (HP:0100021) | 2.39524969 |
76 | Diaphragmatic weakness (HP:0009113) | 2.38380542 |
77 | Spastic diplegia (HP:0001264) | 2.35572182 |
78 | Irritability (HP:0000737) | 2.32728598 |
79 | Late onset (HP:0003584) | 2.32516052 |
80 | Cerebral edema (HP:0002181) | 2.30442650 |
81 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 2.29484527 |
82 | Cardiovascular calcification (HP:0011915) | 2.23234733 |
83 | Glomerulonephritis (HP:0000099) | 2.21981489 |
84 | Hypertensive crisis (HP:0100735) | 2.21942407 |
85 | Esophageal varix (HP:0002040) | 2.21839769 |
86 | Brushfield spots (HP:0001088) | 2.20201826 |
87 | Amyloidosis (HP:0011034) | 2.17955923 |
88 | Abnormality of homocysteine metabolism (HP:0010919) | 2.17767062 |
89 | Homocystinuria (HP:0002156) | 2.17767062 |
90 | Sensorimotor neuropathy (HP:0007141) | 2.17399870 |
91 | Hyperinsulinemic hypoglycemia (HP:0000825) | 2.17373376 |
92 | Mitral stenosis (HP:0001718) | 2.17108116 |
93 | Vomiting (HP:0002013) | 2.15249512 |
94 | Hydroxyprolinuria (HP:0003080) | 2.14948965 |
95 | Abnormality of proline metabolism (HP:0010907) | 2.14948965 |
96 | Pancreatitis (HP:0001733) | 2.14921312 |
97 | Menorrhagia (HP:0000132) | 2.13528416 |
98 | Neonatal onset (HP:0003623) | 2.13233867 |
99 | Abnormality of transition element cation homeostasis (HP:0011030) | 2.13027167 |
100 | Generalized aminoaciduria (HP:0002909) | 2.11696921 |
101 | Abnormality of iron homeostasis (HP:0011031) | 2.09876852 |
102 | Epistaxis (HP:0000421) | 2.09694484 |
103 | Prolonged bleeding time (HP:0003010) | 2.09669312 |
104 | Gingival bleeding (HP:0000225) | 2.09083569 |
105 | * Abnormality of the gallbladder (HP:0005264) | 2.08373846 |
106 | Rickets (HP:0002748) | 2.06779541 |
107 | * Reticulocytosis (HP:0001923) | 2.04346974 |
108 | Enlarged kidneys (HP:0000105) | 2.02856029 |
109 | Opisthotonus (HP:0002179) | 2.02122424 |
110 | Hemorrhage of the eye (HP:0011885) | 2.00878476 |
111 | Thrombophlebitis (HP:0004418) | 2.00639374 |
112 | Abnormality of urine glucose concentration (HP:0011016) | 1.98243202 |
113 | Glycosuria (HP:0003076) | 1.98243202 |
114 | Ileus (HP:0002595) | 1.97473502 |
115 | Recurrent gram-negative bacterial infections (HP:0005420) | 1.96700473 |
116 | Nausea (HP:0002018) | 1.95573009 |
117 | Hypoparathyroidism (HP:0000829) | 1.92918577 |
118 | Purpura (HP:0000979) | 1.92907657 |
119 | Abnormal cartilage morphology (HP:0002763) | 1.92894845 |
120 | Nephritis (HP:0000123) | 1.92813087 |
121 | Hypochromic anemia (HP:0001931) | 1.90796581 |
122 | Birth length less than 3rd percentile (HP:0003561) | 1.90269716 |
123 | Bowel incontinence (HP:0002607) | 1.89995358 |
124 | Proximal tubulopathy (HP:0000114) | 1.86186933 |
125 | Pallor (HP:0000980) | 1.85772835 |
126 | Symptomatic seizures (HP:0011145) | 1.85351956 |
127 | Abnormality of vitamin metabolism (HP:0100508) | 1.83887634 |
128 | Alkalosis (HP:0001948) | 1.83695307 |
129 | Abnormality of the Achilles tendon (HP:0005109) | 1.83114680 |
130 | Hyperglycemia (HP:0003074) | 1.82711132 |
131 | Abnormal large intestine physiology (HP:0012700) | 1.76037396 |
132 | Microcytic anemia (HP:0001935) | 1.75376390 |
133 | Neoplasm of the liver (HP:0002896) | 1.71606184 |
134 | Spastic paraparesis (HP:0002313) | 1.68756626 |
135 | Ventricular fibrillation (HP:0001663) | 1.66544787 |
136 | Ankyloglossia (HP:0010296) | 1.64753426 |
137 | Abnormal number of erythroid precursors (HP:0012131) | 1.63084652 |
138 | Orthostatic hypotension (HP:0001278) | 1.63057194 |
139 | Hypophosphatemic rickets (HP:0004912) | 1.61782991 |
Rank | Gene Set | Z-score |
---|---|---|
1 | BCKDK | 6.74780772 |
2 | ERN1 | 4.44739681 |
3 | SIK1 | 4.38826190 |
4 | FGFR4 | 4.10026250 |
5 | TAOK3 | 3.44568041 |
6 | EEF2K | 3.43986937 |
7 | INSRR | 2.90186805 |
8 | PRPF4B | 2.86768179 |
9 | TTK | 2.73842234 |
10 | MST1R | 2.71594399 |
11 | RIPK4 | 2.68871725 |
12 | KSR2 | 2.68093682 |
13 | ERBB4 | 2.66421611 |
14 | PKN2 | 2.65882860 |
15 | CDK12 | 2.58020136 |
16 | CLK1 | 2.57188990 |
17 | CDC7 | 2.53365560 |
18 | FRK | 2.34677778 |
19 | FLT3 | 2.19868036 |
20 | MAPK11 | 2.11833358 |
21 | SCYL2 | 2.09625056 |
22 | RAF1 | 2.09267862 |
23 | MAP2K4 | 1.99097644 |
24 | TRIB3 | 1.88917854 |
25 | NTRK3 | 1.87271581 |
26 | PTK6 | 1.69509069 |
27 | GRK6 | 1.69502230 |
28 | PIK3CG | 1.66731836 |
29 | TYK2 | 1.66062496 |
30 | MAP3K10 | 1.60570502 |
31 | BUB1 | 1.56004474 |
32 | PLK4 | 1.54630970 |
33 | ABL2 | 1.50201591 |
34 | LATS1 | 1.50119200 |
35 | KDR | 1.40160622 |
36 | RPS6KB2 | 1.34861323 |
37 | DAPK2 | 1.33181023 |
38 | PRKAA2 | 1.29407380 |
39 | JAK2 | 1.28233867 |
40 | SMG1 | 1.27871873 |
41 | BRSK2 | 1.22060801 |
42 | NME1 | 1.21406705 |
43 | NME2 | 1.20059848 |
44 | NEK2 | 1.19957684 |
45 | NEK9 | 1.17158684 |
46 | MAP3K11 | 1.16962100 |
47 | ERBB2 | 1.13631893 |
48 | MAP3K7 | 1.12446953 |
49 | MAP2K3 | 1.11415787 |
50 | WNK4 | 1.07313922 |
51 | MAP3K3 | 1.06753699 |
52 | MET | 1.06054914 |
53 | TBK1 | 1.05207862 |
54 | WEE1 | 1.02595924 |
55 | EIF2AK1 | 1.02556885 |
56 | BRSK1 | 1.01544890 |
57 | BMPR2 | 0.99545496 |
58 | WNK1 | 0.99199755 |
59 | BRAF | 0.94552015 |
60 | CDK6 | 0.94428667 |
61 | TRPM7 | 0.92485103 |
62 | CCNB1 | 0.91278500 |
63 | CHEK2 | 0.89438896 |
64 | KSR1 | 0.88847362 |
65 | MATK | 0.87625172 |
66 | MAPK4 | 0.87274051 |
67 | CDK7 | 0.87246004 |
68 | CHEK1 | 0.86371667 |
69 | PIM2 | 0.85944061 |
70 | SRPK1 | 0.83976338 |
71 | PRKCZ | 0.83188275 |
72 | RIPK1 | 0.82470391 |
73 | DYRK1B | 0.81581575 |
74 | PIM1 | 0.79344721 |
75 | MAPK15 | 0.78570266 |
76 | JAK1 | 0.78470084 |
77 | STK4 | 0.78162022 |
78 | FGFR2 | 0.77910471 |
79 | ATR | 0.77733695 |
80 | CAMK1D | 0.77275038 |
81 | PRKAA1 | 0.76736923 |
82 | PDK2 | 0.75363128 |
83 | CDK2 | 0.75344344 |
84 | TSSK6 | 0.75195195 |
85 | PINK1 | 0.74683768 |
86 | MAP3K14 | 0.74650609 |
87 | CDK1 | 0.73634175 |
88 | MAP2K6 | 0.73624291 |
89 | * PRKACG | 0.70662751 |
90 | MAPKAPK5 | 0.70330757 |
91 | CSK | 0.69575395 |
92 | MAP2K2 | 0.68600132 |
93 | STK38L | 0.68596284 |
94 | ATM | 0.68584754 |
95 | IRAK3 | 0.68359171 |
96 | MAPK12 | 0.67690117 |
97 | GSK3A | 0.66748731 |
98 | EPHB1 | 0.64424674 |
99 | MAP2K1 | 0.63759463 |
100 | BRD4 | 0.63214699 |
101 | PBK | 0.62632977 |
102 | CDK4 | 0.62014975 |
103 | CSNK2A2 | 0.61906015 |
104 | PTK2 | 0.61882470 |
105 | JAK3 | 0.61826995 |
106 | SGK3 | 0.57624434 |
107 | PLK1 | 0.56922735 |
108 | PAK2 | 0.56492361 |
109 | TIE1 | 0.55300434 |
110 | MAPKAPK3 | 0.54756564 |
111 | ALK | 0.54749719 |
112 | CAMK2G | 0.54304640 |
113 | CSNK2A1 | 0.53596407 |
114 | DYRK3 | 0.53593340 |
115 | PDPK1 | 0.52527314 |
116 | TAOK2 | 0.51817480 |
117 | TGFBR2 | 0.51536093 |
118 | CSNK1E | 0.50838012 |
119 | IKBKE | 0.49766076 |
120 | SGK1 | 0.47893579 |
121 | PRKG2 | 0.47722420 |
122 | RPS6KB1 | 0.46573964 |
123 | PLK3 | 0.45689157 |
124 | PRKCQ | 0.43482954 |
125 | ICK | 0.43357874 |
126 | AKT2 | 0.43346108 |
127 | SIK2 | 0.42527800 |
128 | MAP3K5 | 0.41373486 |
129 | GRK1 | 0.41276942 |
130 | AKT1 | 0.39970875 |
131 | GSK3B | 0.39763726 |
132 | EPHA3 | 0.39513145 |
133 | MAPK10 | 0.38851918 |
134 | MAP3K1 | 0.38425436 |
135 | RET | 0.37950608 |
136 | AKT3 | 0.37914179 |
137 | BMX | 0.37800154 |
138 | MAP3K2 | 0.37373772 |
139 | MAPK14 | 0.36539666 |
140 | MTOR | 0.34462532 |
141 | PDK1 | 0.32847499 |
142 | IGF1R | 0.30725550 |
143 | CSF1R | 0.30684195 |
144 | NUAK1 | 0.30677600 |
145 | TAOK1 | 0.30531169 |
146 | MAP3K6 | 0.29145588 |
147 | PRKCA | 0.28493067 |
148 | NEK1 | 0.28361774 |
149 | EGFR | 0.27954628 |
150 | SGK2 | 0.27769074 |
151 | STK3 | 0.27621707 |
152 | CSNK1G1 | 0.27060727 |
153 | MAPK7 | 0.26754199 |
154 | PIK3CA | 0.26715094 |
155 | MAP3K8 | 0.26178766 |
156 | FGFR3 | 0.23499652 |
157 | EPHA2 | 0.22175644 |
158 | PDK3 | 0.20240053 |
159 | PDK4 | 0.20240053 |
160 | STK10 | 0.19363915 |
161 | MAPK3 | 0.19144240 |
162 | PRKCG | 0.18933399 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 4.23038404 |
2 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 3.47733522 |
3 | Nitrogen metabolism_Homo sapiens_hsa00910 | 3.42622516 |
4 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 3.10941003 |
5 | Arginine biosynthesis_Homo sapiens_hsa00220 | 2.94369505 |
6 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 2.67749096 |
7 | Tryptophan metabolism_Homo sapiens_hsa00380 | 2.66675430 |
8 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 2.60619080 |
9 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 2.53489904 |
10 | Fatty acid degradation_Homo sapiens_hsa00071 | 2.48298912 |
11 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 2.46428899 |
12 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 2.32487784 |
13 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 2.32291664 |
14 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 2.19018041 |
15 | Butanoate metabolism_Homo sapiens_hsa00650 | 2.12010961 |
16 | Peroxisome_Homo sapiens_hsa04146 | 2.00969392 |
17 | Histidine metabolism_Homo sapiens_hsa00340 | 1.96320812 |
18 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.95567598 |
19 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 1.94651961 |
20 | PPAR signaling pathway_Homo sapiens_hsa03320 | 1.89537344 |
21 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.88188991 |
22 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.82605378 |
23 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 1.81657958 |
24 | Fatty acid metabolism_Homo sapiens_hsa01212 | 1.80773743 |
25 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.75932225 |
26 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 1.68779763 |
27 | Retinol metabolism_Homo sapiens_hsa00830 | 1.67566313 |
28 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.66446353 |
29 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.62769319 |
30 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 1.61249508 |
31 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.61186803 |
32 | Bile secretion_Homo sapiens_hsa04976 | 1.60947626 |
33 | Fat digestion and absorption_Homo sapiens_hsa04975 | 1.60661874 |
34 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.56915983 |
35 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.53151439 |
36 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.52534943 |
37 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 1.46977522 |
38 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 1.46752487 |
39 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 1.43611199 |
40 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.40309757 |
41 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.37244308 |
42 | Tyrosine metabolism_Homo sapiens_hsa00350 | 1.33927042 |
43 | * Pyruvate metabolism_Homo sapiens_hsa00620 | 1.31005835 |
44 | ABC transporters_Homo sapiens_hsa02010 | 1.29820894 |
45 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.28101545 |
46 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.25291384 |
47 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.20780139 |
48 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.14967635 |
49 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 1.14534913 |
50 | * Carbon metabolism_Homo sapiens_hsa01200 | 1.13992965 |
51 | * Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.11678434 |
52 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.10605308 |
53 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.03891864 |
54 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 1.01272663 |
55 | * Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.00663340 |
56 | Sulfur relay system_Homo sapiens_hsa04122 | 0.99556095 |
57 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.94850553 |
58 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.92603862 |
59 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.91280597 |
60 | DNA replication_Homo sapiens_hsa03030 | 0.87101268 |
61 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.83895641 |
62 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.83848652 |
63 | Lysine degradation_Homo sapiens_hsa00310 | 0.82660765 |
64 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.81477584 |
65 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.76751261 |
66 | * Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.71822431 |
67 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.70531835 |
68 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.62251625 |
69 | Mismatch repair_Homo sapiens_hsa03430 | 0.60822758 |
70 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.57328967 |
71 | Other glycan degradation_Homo sapiens_hsa00511 | 0.51703796 |
72 | * Metabolic pathways_Homo sapiens_hsa01100 | 0.48837539 |
73 | Galactose metabolism_Homo sapiens_hsa00052 | 0.47860706 |
74 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.43937810 |
75 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.41142938 |
76 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.34297724 |
77 | Base excision repair_Homo sapiens_hsa03410 | 0.30385341 |
78 | Cell cycle_Homo sapiens_hsa04110 | 0.29587217 |
79 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.27713422 |
80 | RNA transport_Homo sapiens_hsa03013 | 0.26346361 |
81 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.23998247 |
82 | Homologous recombination_Homo sapiens_hsa03440 | 0.22892819 |
83 | Insulin resistance_Homo sapiens_hsa04931 | 0.22708903 |
84 | Prion diseases_Homo sapiens_hsa05020 | 0.21784050 |
85 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.21357429 |
86 | Spliceosome_Homo sapiens_hsa03040 | 0.20841658 |
87 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.20249244 |
88 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.19750661 |
89 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.19171176 |
90 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.17830455 |
91 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.13688910 |
92 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.12702136 |
93 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.07896746 |
94 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.06939955 |
95 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.06131148 |
96 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.05878128 |
97 | Thyroid cancer_Homo sapiens_hsa05216 | 0.04711328 |
98 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.03015922 |
99 | Mineral absorption_Homo sapiens_hsa04978 | 0.01054977 |
100 | Ether lipid metabolism_Homo sapiens_hsa00565 | -0.2328411 |
101 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | -0.2148005 |
102 | Regulation of autophagy_Homo sapiens_hsa04140 | -0.1883135 |
103 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | -0.1852057 |
104 | Bladder cancer_Homo sapiens_hsa05219 | -0.1796855 |
105 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | -0.1684094 |
106 | * Insulin signaling pathway_Homo sapiens_hsa04910 | -0.1588099 |
107 | Hepatitis C_Homo sapiens_hsa05160 | -0.1582801 |
108 | African trypanosomiasis_Homo sapiens_hsa05143 | -0.1565012 |
109 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | -0.1563662 |
110 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | -0.1475090 |
111 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | -0.1456779 |
112 | Protein digestion and absorption_Homo sapiens_hsa04974 | -0.1365477 |
113 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | -0.1275527 |
114 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | -0.1230970 |
115 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | -0.0646602 |
116 | * Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | -0.0429850 |
117 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | -0.0172634 |