Rank | Gene Set | Z-score |
---|---|---|
1 | COPI coating of Golgi vesicle (GO:0048205) | 6.08710122 |
2 | Golgi transport vesicle coating (GO:0048200) | 6.08710122 |
3 | DNA unwinding involved in DNA replication (GO:0006268) | 5.45303253 |
4 | IMP biosynthetic process (GO:0006188) | 4.87710908 |
5 | nuclear pore organization (GO:0006999) | 4.83773105 |
6 | protein localization to endosome (GO:0036010) | 4.71438790 |
7 | regulation of gene silencing by miRNA (GO:0060964) | 4.70805971 |
8 | regulation of gene silencing by RNA (GO:0060966) | 4.70805971 |
9 | regulation of posttranscriptional gene silencing (GO:0060147) | 4.70805971 |
10 | maintenance of protein localization in endoplasmic reticulum (GO:0035437) | 4.57108408 |
11 | nuclear pore complex assembly (GO:0051292) | 4.50852903 |
12 | folic acid-containing compound biosynthetic process (GO:0009396) | 4.49764497 |
13 | regulation of translational fidelity (GO:0006450) | 4.47897046 |
14 | hemidesmosome assembly (GO:0031581) | 4.47214685 |
15 | protein localization to kinetochore (GO:0034501) | 4.46797667 |
16 | protein retention in ER lumen (GO:0006621) | 4.45892377 |
17 | peptidyl-arginine omega-N-methylation (GO:0035247) | 4.41400800 |
18 | pre-miRNA processing (GO:0031054) | 4.36801332 |
19 | regulation of translational termination (GO:0006449) | 4.29885852 |
20 | IMP metabolic process (GO:0046040) | 4.22837408 |
21 | mitotic nuclear envelope disassembly (GO:0007077) | 4.17305070 |
22 | heterochromatin organization (GO:0070828) | 4.16416895 |
23 | retrograde vesicle-mediated transport, Golgi to ER (GO:0006890) | 4.05680326 |
24 | nuclear envelope disassembly (GO:0051081) | 3.98067364 |
25 | membrane disassembly (GO:0030397) | 3.98067364 |
26 | skin morphogenesis (GO:0043589) | 3.96419008 |
27 | cell adhesion mediated by integrin (GO:0033627) | 3.93724571 |
28 | DNA replication-dependent nucleosome assembly (GO:0006335) | 3.92249310 |
29 | DNA replication-dependent nucleosome organization (GO:0034723) | 3.92249310 |
30 | cell-substrate junction assembly (GO:0007044) | 3.90927611 |
31 | paraxial mesoderm development (GO:0048339) | 3.89059322 |
32 | mitotic sister chromatid segregation (GO:0000070) | 3.83190631 |
33 | peptidyl-arginine N-methylation (GO:0035246) | 3.82554902 |
34 | peptidyl-arginine methylation (GO:0018216) | 3.82554902 |
35 | histone arginine methylation (GO:0034969) | 3.80647030 |
36 | nucleobase biosynthetic process (GO:0046112) | 3.78205465 |
37 | activation of Rac GTPase activity (GO:0032863) | 3.77010348 |
38 | DNA replication initiation (GO:0006270) | 3.74666063 |
39 | sister chromatid segregation (GO:0000819) | 3.73929854 |
40 | adherens junction assembly (GO:0034333) | 3.67497678 |
41 | cell-substrate adherens junction assembly (GO:0007045) | 3.66073188 |
42 | focal adhesion assembly (GO:0048041) | 3.66073188 |
43 | DNA duplex unwinding (GO:0032508) | 3.63318977 |
44 | DNA geometric change (GO:0032392) | 3.62526246 |
45 | cytoskeletal anchoring at plasma membrane (GO:0007016) | 3.58053669 |
46 | protein maturation by protein folding (GO:0022417) | 3.57722015 |
47 | regulation of early endosome to late endosome transport (GO:2000641) | 3.56710107 |
48 | spliceosomal tri-snRNP complex assembly (GO:0000244) | 3.55151310 |
49 | DNA strand elongation involved in DNA replication (GO:0006271) | 3.54500252 |
50 | pentose-phosphate shunt (GO:0006098) | 3.53315726 |
51 | regulation of attachment of spindle microtubules to kinetochore (GO:0051988) | 3.51652547 |
52 | glucose 6-phosphate metabolic process (GO:0051156) | 3.51450751 |
53 | barbed-end actin filament capping (GO:0051016) | 3.50903650 |
54 | regulation of mammary gland epithelial cell proliferation (GO:0033599) | 3.47784398 |
55 | protein localization to chromosome, centromeric region (GO:0071459) | 3.39672403 |
56 | peptidyl-proline hydroxylation (GO:0019511) | 3.38277432 |
57 | protein hydroxylation (GO:0018126) | 3.37042540 |
58 | positive regulation of SMAD protein import into nucleus (GO:0060391) | 3.35527772 |
59 | DNA strand elongation (GO:0022616) | 3.32249105 |
60 | peptidyl-lysine dimethylation (GO:0018027) | 3.29452794 |
61 | formation of translation preinitiation complex (GO:0001731) | 3.28063945 |
62 | pore complex assembly (GO:0046931) | 3.26818465 |
63 | dichotomous subdivision of an epithelial terminal unit (GO:0060600) | 3.26452697 |
64 | mitotic chromosome condensation (GO:0007076) | 3.20852738 |
65 | mitotic metaphase plate congression (GO:0007080) | 3.20265764 |
66 | negative regulation of histone methylation (GO:0031061) | 3.20166950 |
67 | regulation of spindle organization (GO:0090224) | 3.15755634 |
68 | mitotic nuclear envelope reassembly (GO:0007084) | 3.14334187 |
69 | nuclear envelope reassembly (GO:0031468) | 3.14334187 |
70 | regulation of mitotic spindle organization (GO:0060236) | 3.13882124 |
71 | nucleobase-containing small molecule interconversion (GO:0015949) | 3.12823777 |
72 | negative regulation of mRNA splicing, via spliceosome (GO:0048025) | 3.11870530 |
73 | * glycolytic process (GO:0006096) | 3.10953819 |
74 | purine nucleobase biosynthetic process (GO:0009113) | 3.10804354 |
75 | NADPH regeneration (GO:0006740) | 3.09911612 |
76 | planar cell polarity pathway involved in neural tube closure (GO:0090179) | 3.09744889 |
77 | proline biosynthetic process (GO:0006561) | 3.08976932 |
78 | epithelial cell-cell adhesion (GO:0090136) | 3.08631369 |
79 | nuclear envelope organization (GO:0006998) | 3.08103438 |
80 | dosage compensation (GO:0007549) | 3.07536156 |
81 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 3.07038105 |
82 | glucose catabolic process (GO:0006007) | 3.01375119 |
83 | chromatin assembly (GO:0031497) | 3.01004072 |
84 | postreplication repair (GO:0006301) | 2.99063996 |
85 | regulation of histone H3-K9 methylation (GO:0051570) | 2.98645968 |
86 | activation of signaling protein activity involved in unfolded protein response (GO:0006987) | 2.98101409 |
87 | negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471) | 2.97748643 |
88 | basement membrane organization (GO:0071711) | 2.94639045 |
89 | regulation of sister chromatid cohesion (GO:0007063) | 2.94075061 |
90 | cellular protein complex localization (GO:0034629) | 2.93444450 |
91 | positive regulation of nuclease activity (GO:0032075) | 2.93261420 |
92 | vesicle coating (GO:0006901) | 2.85615141 |
93 | regulation of protein heterodimerization activity (GO:0043497) | 2.85526635 |
94 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 2.85360101 |
95 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 2.85360101 |
96 | regulation of SMAD protein import into nucleus (GO:0060390) | 2.85087388 |
97 | ribosome assembly (GO:0042255) | 2.84980724 |
98 | positive regulation of chromosome segregation (GO:0051984) | 2.84932941 |
99 | stress fiber assembly (GO:0043149) | 2.83719926 |
100 | establishment of apical/basal cell polarity (GO:0035089) | 2.83247016 |
101 | regulation of centrosome cycle (GO:0046605) | 2.83164415 |
102 | protein localization to microtubule (GO:0035372) | 2.81104309 |
103 | regulation of establishment of planar polarity involved in neural tube closure (GO:0090178) | 2.81100889 |
104 | endoplasmic reticulum unfolded protein response (GO:0030968) | 2.81005407 |
105 | regulation of glucose import in response to insulin stimulus (GO:2001273) | 2.80746608 |
106 | desmosome organization (GO:0002934) | 2.80672331 |
107 | nodal signaling pathway (GO:0038092) | 2.80010482 |
108 | regulation of centriole replication (GO:0046599) | 2.79141248 |
109 | pinocytosis (GO:0006907) | 2.76200488 |
110 | translesion synthesis (GO:0019985) | 2.75472378 |
111 | negative regulation of cell size (GO:0045792) | 2.75307379 |
112 | tRNA aminoacylation for protein translation (GO:0006418) | 2.74665359 |
113 | regulation of chromosome segregation (GO:0051983) | 2.74054928 |
114 | membrane protein ectodomain proteolysis (GO:0006509) | 2.73520974 |
115 | positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling | 2.73053196 |
116 | metaphase plate congression (GO:0051310) | 2.72336782 |
117 | semaphorin-plexin signaling pathway (GO:0071526) | 2.72109416 |
118 | protein export from nucleus (GO:0006611) | 2.71348630 |
119 | endodermal cell differentiation (GO:0035987) | 2.71311120 |
120 | histone H2A monoubiquitination (GO:0035518) | 2.70593099 |
121 | ER-nucleus signaling pathway (GO:0006984) | 2.70180479 |
122 | positive regulation of extrinsic apoptotic signaling pathway in absence of ligand (GO:2001241) | 2.69280358 |
123 | membrane raft organization (GO:0031579) | 2.68544097 |
124 | telomere maintenance via semi-conservative replication (GO:0032201) | 2.67768484 |
125 | mitotic G1 DNA damage checkpoint (GO:0031571) | 2.66864258 |
126 | DNA conformation change (GO:0071103) | 2.65803446 |
127 | negative regulation of chromosome segregation (GO:0051985) | 2.65363131 |
128 | regulation of nuclease activity (GO:0032069) | 2.65226561 |
129 | positive regulation of RNA splicing (GO:0033120) | 2.64817011 |
130 | establishment of chromosome localization (GO:0051303) | 2.64542690 |
131 | tRNA aminoacylation (GO:0043039) | 2.64183870 |
132 | amino acid activation (GO:0043038) | 2.64183870 |
133 | NLS-bearing protein import into nucleus (GO:0006607) | 2.64129831 |
134 | regulation of gene silencing (GO:0060968) | 2.63566016 |
135 | establishment of integrated proviral latency (GO:0075713) | 2.63357866 |
136 | regulation of helicase activity (GO:0051095) | 2.62673779 |
137 | glucocorticoid receptor signaling pathway (GO:0042921) | 2.62406095 |
138 | branching involved in mammary gland duct morphogenesis (GO:0060444) | 2.58598122 |
139 | maternal placenta development (GO:0001893) | 2.58407385 |
140 | cortical actin cytoskeleton organization (GO:0030866) | 2.58226474 |
141 | negative regulation of mitotic sister chromatid segregation (GO:0033048) | 2.58108230 |
142 | negative regulation of mitotic metaphase/anaphase transition (GO:0045841) | 2.58108230 |
143 | negative regulation of sister chromatid segregation (GO:0033046) | 2.58108230 |
144 | negative regulation of mitotic sister chromatid separation (GO:2000816) | 2.58108230 |
145 | cellular response to unfolded protein (GO:0034620) | 2.58106014 |
146 | mitotic spindle assembly checkpoint (GO:0007094) | 2.58006482 |
147 | regulation of hippo signaling (GO:0035330) | 2.57485403 |
148 | chaperone-mediated protein complex assembly (GO:0051131) | 2.57084516 |
149 | establishment of viral latency (GO:0019043) | 2.56114848 |
150 | negative regulation of RNA splicing (GO:0033119) | 2.56044194 |
151 | positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling | 2.55814485 |
152 | regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway | 2.55814485 |
153 | negative regulation of DNA repair (GO:0045738) | 2.55787686 |
154 | spindle assembly checkpoint (GO:0071173) | 2.54719881 |
155 | mRNA transport (GO:0051028) | 2.54382316 |
156 | polarized epithelial cell differentiation (GO:0030859) | 2.54081800 |
157 | positive regulation of blood vessel endothelial cell migration (GO:0043536) | 2.54042739 |
158 | apoptotic process involved in morphogenesis (GO:0060561) | 2.54038917 |
159 | chromosome condensation (GO:0030261) | 2.53858772 |
160 | regulation of translational elongation (GO:0006448) | 2.53046961 |
161 | endoplasmic reticulum calcium ion homeostasis (GO:0032469) | 2.52786728 |
162 | ribosome biogenesis (GO:0042254) | 2.52469684 |
163 | mRNA stabilization (GO:0048255) | 2.52261178 |
164 | RNA stabilization (GO:0043489) | 2.52261178 |
165 | negative regulation of gene silencing (GO:0060969) | 2.51955948 |
166 | protein complex localization (GO:0031503) | 2.51139355 |
167 | hypotonic response (GO:0006971) | 2.48545432 |
168 | positive regulation of syncytium formation by plasma membrane fusion (GO:0060143) | 2.46821983 |
169 | endothelial cell chemotaxis (GO:0035767) | 2.46574995 |
170 | 4-hydroxyproline metabolic process (GO:0019471) | 2.43865785 |
171 | mitotic cytokinesis (GO:0000281) | 2.42600359 |
172 | apoptotic cell clearance (GO:0043277) | 2.42346257 |
173 | cellular copper ion homeostasis (GO:0006878) | 2.41730536 |
174 | mammary gland epithelial cell proliferation (GO:0033598) | 2.41071428 |
175 | mesodermal cell differentiation (GO:0048333) | 2.39961146 |
176 | regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547) | 2.39747842 |
177 | endothelial cell morphogenesis (GO:0001886) | 2.38238311 |
178 | negative regulation of chondrocyte differentiation (GO:0032331) | 2.37257935 |
179 | regulation of protein export from nucleus (GO:0046825) | 2.34757596 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 8.76810407 |
2 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 4.92869287 |
3 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 3.67741841 |
4 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 3.53899465 |
5 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 3.26024429 |
6 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 3.12566911 |
7 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 3.02061839 |
8 | * FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.56315215 |
9 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 2.54780763 |
10 | MYC_22102868_ChIP-Seq_BL_Human | 2.44304563 |
11 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 2.39601913 |
12 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.39385388 |
13 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 2.35791473 |
14 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 2.26587163 |
15 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 2.24482313 |
16 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 2.20418110 |
17 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 2.18891087 |
18 | XRN2_22483619_ChIP-Seq_HELA_Human | 2.16928389 |
19 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.11821648 |
20 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 2.07933974 |
21 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 2.00393748 |
22 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 1.99772773 |
23 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 1.98767092 |
24 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.95526993 |
25 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.90948713 |
26 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.89850281 |
27 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.89614644 |
28 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.88157586 |
29 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 1.85093048 |
30 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.82238126 |
31 | ZIC3_20872845_ChIP-ChIP_MESCs_Mouse | 1.81687146 |
32 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.81017310 |
33 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 1.74201162 |
34 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.72888783 |
35 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.72781082 |
36 | P300_27058665_Chip-Seq_ZR-75-30cells_Human | 1.69608162 |
37 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.67509985 |
38 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 1.66036407 |
39 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 1.65275180 |
40 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 1.65233319 |
41 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.64680905 |
42 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.64618801 |
43 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.64054205 |
44 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 1.59076666 |
45 | SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 1.56635901 |
46 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.55993072 |
47 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.55735019 |
48 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.55226759 |
49 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 1.55058887 |
50 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.52404815 |
51 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.52388385 |
52 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.51440901 |
53 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.50719638 |
54 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.50178610 |
55 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 1.49875607 |
56 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.49862549 |
57 | TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.48220425 |
58 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 1.47073306 |
59 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.46503186 |
60 | TCF3_18692474_ChIP-Seq_MEFs_Mouse | 1.46094479 |
61 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.44667604 |
62 | UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 1.44529345 |
63 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 1.43711890 |
64 | SALL4_18804426_ChIP-ChIP_MESCs_Mouse | 1.42595563 |
65 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.41219845 |
66 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.39090690 |
67 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.37560596 |
68 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.35485561 |
69 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 1.35238516 |
70 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 1.34821822 |
71 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.34430103 |
72 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 1.33916544 |
73 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 1.33916544 |
74 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 1.33916544 |
75 | SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 1.33029482 |
76 | SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 1.33029482 |
77 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.32679688 |
78 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.32355006 |
79 | UBF1/2_26484160_Chip-Seq_HMECs_Human | 1.32332482 |
80 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 1.31727079 |
81 | TP53_22127205_ChIP-Seq_IMR90_Human | 1.30850838 |
82 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.29339360 |
83 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.28842664 |
84 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.27998178 |
85 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.27887226 |
86 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.27485518 |
87 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.26933533 |
88 | CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.26736430 |
89 | NANOG_21062744_ChIP-ChIP_HESCs_Human | 1.26191870 |
90 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.25739172 |
91 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.25472992 |
92 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.25435220 |
93 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.23859065 |
94 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.23207016 |
95 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.18914883 |
96 | KDM2B_26808549_Chip-Seq_K562_Human | 1.18640053 |
97 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.18149252 |
98 | NACC1_18358816_ChIP-ChIP_MESCs_Mouse | 1.17859672 |
99 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.16927150 |
100 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.16880512 |
101 | ZFP281_27345836_Chip-Seq_ESCs_Mouse | 1.14589612 |
102 | ATF3_27146783_Chip-Seq_COLON_Human | 1.14086281 |
103 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.13554561 |
104 | ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.13478327 |
105 | NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 1.12392292 |
106 | OCT4_18692474_ChIP-Seq_MEFs_Mouse | 1.11891721 |
107 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 1.11760475 |
108 | SOX2_18358816_ChIP-ChIP_MESCs_Mouse | 1.10689791 |
109 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.10661930 |
110 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.09232360 |
111 | NKX2-5_21415370_ChIP-Seq_HL-1_Mouse | 1.09102564 |
112 | TCF3_18692474_ChIP-Seq_MESCs_Mouse | 1.08909576 |
113 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.08258094 |
114 | NANOG_18347094_ChIP-ChIP_MESCs_Mouse | 1.08140319 |
115 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.07303250 |
116 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.06780537 |
117 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 1.06092051 |
118 | SREBP1_19666523_ChIP-Seq_LIVER_Mouse | 1.05378595 |
119 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 1.04605339 |
120 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.04378082 |
121 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.04260598 |
122 | ATF3_23680149_ChIP-Seq_GBM1-GSC_Human | 1.04235054 |
123 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 1.03391497 |
124 | TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 1.02748299 |
125 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.01512718 |
126 | CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.01459023 |
127 | EOMES_20176728_ChIP-ChIP_TSCs_Mouse | 1.01308544 |
128 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.01093957 |
129 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.00507993 |
130 | EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 0.98424364 |
131 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 0.98102166 |
132 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 0.97429848 |
133 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 0.96061383 |
134 | POU5F1_16518401_ChIP-PET_MESCs_Mouse | 0.95744331 |
135 | SOX2_18692474_ChIP-Seq_MEFs_Mouse | 0.94786714 |
136 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 0.94631319 |
137 | NCOR1_26117541_ChIP-Seq_K562_Human | 0.94155471 |
138 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 0.93839039 |
139 | DMRT1_23473982_ChIP-Seq_TESTES_Mouse | 0.93521470 |
140 | ZNF263_19887448_ChIP-Seq_K562_Human | 0.92716638 |
141 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 0.92658102 |
142 | SOX2_18692474_ChIP-Seq_MESCs_Mouse | 0.92644560 |
143 | TCFCP2L1_18555785_ChIP-Seq_MESCs_Mouse | 0.91287312 |
144 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 0.91054156 |
145 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 0.90594186 |
146 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.90375970 |
147 | CLOCK_20551151_ChIP-Seq_293T_Human | 0.90179040 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003111_abnormal_nucleus_morphology | 3.24929761 |
2 | MP0010352_gastrointestinal_tract_polyps | 3.11209657 |
3 | MP0004957_abnormal_blastocyst_morpholog | 3.07014855 |
4 | MP0010094_abnormal_chromosome_stability | 3.06591462 |
5 | MP0003705_abnormal_hypodermis_morpholog | 2.99404981 |
6 | MP0003123_paternal_imprinting | 2.88538821 |
7 | MP0003077_abnormal_cell_cycle | 2.83030038 |
8 | MP0005257_abnormal_intraocular_pressure | 2.82513351 |
9 | MP0003693_abnormal_embryo_hatching | 2.82359543 |
10 | MP0010030_abnormal_orbit_morphology | 2.70436445 |
11 | MP0005076_abnormal_cell_differentiation | 2.52535370 |
12 | MP0010307_abnormal_tumor_latency | 2.51943485 |
13 | MP0001730_embryonic_growth_arrest | 2.50174289 |
14 | MP0002653_abnormal_ependyma_morphology | 2.41680898 |
15 | MP0003283_abnormal_digestive_organ | 2.33833231 |
16 | MP0004233_abnormal_muscle_weight | 2.31350049 |
17 | MP0005451_abnormal_body_composition | 2.14731658 |
18 | MP0008007_abnormal_cellular_replicative | 2.14710434 |
19 | MP0000350_abnormal_cell_proliferation | 2.10398309 |
20 | MP0000537_abnormal_urethra_morphology | 2.10145116 |
21 | MP0002084_abnormal_developmental_patter | 1.94404647 |
22 | MP0008932_abnormal_embryonic_tissue | 1.91705443 |
23 | MP0010234_abnormal_vibrissa_follicle | 1.87486946 |
24 | MP0001348_abnormal_lacrimal_gland | 1.87162952 |
25 | MP0003121_genomic_imprinting | 1.86307419 |
26 | MP0005623_abnormal_meninges_morphology | 1.86095960 |
27 | MP0002060_abnormal_skin_morphology | 1.82221332 |
28 | MP0001697_abnormal_embryo_size | 1.80471809 |
29 | MP0004197_abnormal_fetal_growth/weight/ | 1.80092870 |
30 | MP0002085_abnormal_embryonic_tissue | 1.80077374 |
31 | MP0005058_abnormal_lysosome_morphology | 1.79780384 |
32 | MP0001672_abnormal_embryogenesis/_devel | 1.79000142 |
33 | MP0005380_embryogenesis_phenotype | 1.79000142 |
34 | MP0003453_abnormal_keratinocyte_physiol | 1.78645662 |
35 | MP0003566_abnormal_cell_adhesion | 1.73661317 |
36 | MP0000579_abnormal_nail_morphology | 1.72642849 |
37 | MP0003984_embryonic_growth_retardation | 1.66304677 |
38 | MP0003890_abnormal_embryonic-extraembry | 1.64431121 |
39 | MP0001849_ear_inflammation | 1.63731893 |
40 | MP0002088_abnormal_embryonic_growth/wei | 1.63155600 |
41 | MP0002080_prenatal_lethality | 1.63052933 |
42 | MP0008260_abnormal_autophagy | 1.58242091 |
43 | MP0003119_abnormal_digestive_system | 1.55929006 |
44 | MP0004133_heterotaxia | 1.53983412 |
45 | MP0004185_abnormal_adipocyte_glucose | 1.53917735 |
46 | MP0008058_abnormal_DNA_repair | 1.49415533 |
47 | MP0008057_abnormal_DNA_replication | 1.49058652 |
48 | MP0002086_abnormal_extraembryonic_tissu | 1.46404212 |
49 | MP0005501_abnormal_skin_physiology | 1.43127737 |
50 | MP0000733_abnormal_muscle_development | 1.41992960 |
51 | MP0000762_abnormal_tongue_morphology | 1.41682040 |
52 | MP0003329_amyloid_beta_deposits | 1.40759348 |
53 | MP0002796_impaired_skin_barrier | 1.39592738 |
54 | MP0004084_abnormal_cardiac_muscle | 1.37514340 |
55 | MP0003191_abnormal_cellular_cholesterol | 1.36120254 |
56 | MP0000003_abnormal_adipose_tissue | 1.30913311 |
57 | MP0008877_abnormal_DNA_methylation | 1.30135306 |
58 | MP0002877_abnormal_melanocyte_morpholog | 1.29849659 |
59 | MP0000428_abnormal_craniofacial_morphol | 1.26764356 |
60 | MP0000747_muscle_weakness | 1.26021619 |
61 | MP0005023_abnormal_wound_healing | 1.25841873 |
62 | MP0009840_abnormal_foam_cell | 1.23976536 |
63 | MP0009053_abnormal_anal_canal | 1.23086275 |
64 | MP0001293_anophthalmia | 1.22342533 |
65 | MP0002234_abnormal_pharynx_morphology | 1.21045142 |
66 | MP0005409_darkened_coat_color | 1.20949918 |
67 | MP0003300_gastrointestinal_ulcer | 1.20746114 |
68 | MP0002896_abnormal_bone_mineralization | 1.20098843 |
69 | MP0001958_emphysema | 1.18327864 |
70 | MP0000750_abnormal_muscle_regeneration | 1.13019512 |
71 | MP0001216_abnormal_epidermal_layer | 1.10891875 |
72 | MP0002089_abnormal_postnatal_growth/wei | 1.07287774 |
73 | MP0003122_maternal_imprinting | 1.06753685 |
74 | MP0003941_abnormal_skin_development | 1.05060253 |
75 | MP0006072_abnormal_retinal_apoptosis | 1.04093592 |
76 | MP0000313_abnormal_cell_death | 1.02415473 |
77 | MP0008438_abnormal_cutaneous_collagen | 1.02387153 |
78 | MP0002111_abnormal_tail_morphology | 1.02347828 |
79 | MP0003115_abnormal_respiratory_system | 1.01469887 |
80 | MP0004808_abnormal_hematopoietic_stem | 1.00372126 |
81 | MP0000534_abnormal_ureter_morphology | 1.00291835 |
82 | MP0009672_abnormal_birth_weight | 0.99119550 |
83 | MP0003567_abnormal_fetal_cardiomyocyte | 0.98367269 |
84 | MP0003861_abnormal_nervous_system | 0.98243428 |
85 | MP0002697_abnormal_eye_size | 0.97706340 |
86 | MP0005197_abnormal_uvea_morphology | 0.96668325 |
87 | MP0000678_abnormal_parathyroid_gland | 0.96309119 |
88 | MP0001243_abnormal_dermal_layer | 0.95903433 |
89 | MP0002269_muscular_atrophy | 0.93965243 |
90 | MP0000749_muscle_degeneration | 0.93522741 |
91 | MP0001915_intracranial_hemorrhage | 0.93475109 |
92 | MP0005275_abnormal_skin_tensile | 0.93007849 |
93 | MP0002925_abnormal_cardiovascular_devel | 0.90428908 |
94 | MP0000467_abnormal_esophagus_morphology | 0.90230978 |
95 | MP0000358_abnormal_cell_content/ | 0.89430413 |
96 | MP0005384_cellular_phenotype | 0.88870922 |
97 | MP0003937_abnormal_limbs/digits/tail_de | 0.88819844 |
98 | MP0005621_abnormal_cell_physiology | 0.87743393 |
99 | MP0003091_abnormal_cell_migration | 0.87659551 |
100 | MP0000767_abnormal_smooth_muscle | 0.86611506 |
101 | MP0004858_abnormal_nervous_system | 0.85700592 |
102 | MP0009780_abnormal_chondrocyte_physiolo | 0.84669457 |
103 | MP0003385_abnormal_body_wall | 0.83406876 |
104 | MP0004947_skin_inflammation | 0.83235949 |
105 | MP0004510_myositis | 0.83008557 |
106 | MP0003950_abnormal_plasma_membrane | 0.82304471 |
107 | MP0005165_increased_susceptibility_to | 0.81072968 |
108 | MP0005394_taste/olfaction_phenotype | 0.81003829 |
109 | MP0005499_abnormal_olfactory_system | 0.81003829 |
110 | MP0010771_integument_phenotype | 0.80856782 |
111 | MP0002019_abnormal_tumor_incidence | 0.80854933 |
112 | MP0008770_decreased_survivor_rate | 0.80699034 |
113 | MP0003942_abnormal_urinary_system | 0.79471957 |
114 | MP0009703_decreased_birth_body | 0.79433378 |
115 | MP0000627_abnormal_mammary_gland | 0.79247425 |
116 | MP0004272_abnormal_basement_membrane | 0.79025937 |
117 | MP0003315_abnormal_perineum_morphology | 0.78942232 |
118 | MP0000569_abnormal_digit_pigmentation | 0.78432890 |
119 | MP0003221_abnormal_cardiomyocyte_apopto | 0.76981694 |
120 | MP0000490_abnormal_crypts_of | 0.76638566 |
121 | MP0003935_abnormal_craniofacial_develop | 0.75993027 |
122 | MP0003634_abnormal_glial_cell | 0.75979599 |
123 | MP0005330_cardiomyopathy | 0.75978478 |
124 | MP0008789_abnormal_olfactory_epithelium | 0.75373079 |
125 | MP0005375_adipose_tissue_phenotype | 0.74935535 |
126 | MP0003448_altered_tumor_morphology | 0.74683129 |
127 | MP0000858_altered_metastatic_potential | 0.73231385 |
128 | MP0004087_abnormal_muscle_fiber | 0.73082000 |
129 | MP0000266_abnormal_heart_morphology | 0.72377593 |
130 | MP0003279_aneurysm | 0.72315645 |
131 | MP0009278_abnormal_bone_marrow | 0.69765772 |
132 | MP0002092_abnormal_eye_morphology | 0.68473837 |
133 | MP0010630_abnormal_cardiac_muscle | 0.68097767 |
134 | MP0001299_abnormal_eye_distance/ | 0.67332149 |
135 | MP0003787_abnormal_imprinting | 0.67021579 |
136 | MP0000751_myopathy | 0.66104859 |
137 | MP0000759_abnormal_skeletal_muscle | 0.64529116 |
138 | MP0000432_abnormal_head_morphology | 0.63226338 |
139 | MP0005391_vision/eye_phenotype | 0.62017500 |
140 | MP0002081_perinatal_lethality | 0.61754519 |
141 | MP0002751_abnormal_autonomic_nervous | 0.61389072 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Premature rupture of membranes (HP:0001788) | 5.08748658 |
2 | Ependymoma (HP:0002888) | 4.54185058 |
3 | Abnormality of the astrocytes (HP:0100707) | 3.78583509 |
4 | Astrocytoma (HP:0009592) | 3.78583509 |
5 | Vertebral compression fractures (HP:0002953) | 3.33634774 |
6 | Distal lower limb amyotrophy (HP:0008944) | 3.26071927 |
7 | Selective tooth agenesis (HP:0001592) | 3.08133097 |
8 | Atrophic scars (HP:0001075) | 3.07218267 |
9 | Short nail (HP:0001799) | 3.00628542 |
10 | Achilles tendon contracture (HP:0001771) | 2.92983996 |
11 | Ulnar bowing (HP:0003031) | 2.89220308 |
12 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 2.87826729 |
13 | Osteolytic defects of the hand bones (HP:0009699) | 2.87826729 |
14 | Glioma (HP:0009733) | 2.86255208 |
15 | Agnosia (HP:0010524) | 2.85570280 |
16 | Increased connective tissue (HP:0009025) | 2.82345165 |
17 | Medulloblastoma (HP:0002885) | 2.79737465 |
18 | Broad face (HP:0000283) | 2.77251061 |
19 | Hyperacusis (HP:0010780) | 2.74477055 |
20 | Abnormality of the labia minora (HP:0012880) | 2.73488205 |
21 | Distal lower limb muscle weakness (HP:0009053) | 2.70633851 |
22 | Fragile skin (HP:0001030) | 2.68934091 |
23 | Colon cancer (HP:0003003) | 2.67881416 |
24 | Hand muscle atrophy (HP:0009130) | 2.66949546 |
25 | Exercise-induced muscle cramps (HP:0003710) | 2.65986690 |
26 | Lower limb amyotrophy (HP:0007210) | 2.60894822 |
27 | Deviation of the thumb (HP:0009603) | 2.60561587 |
28 | Spinal rigidity (HP:0003306) | 2.60468358 |
29 | Abnormality of the Achilles tendon (HP:0005109) | 2.56217604 |
30 | Cholecystitis (HP:0001082) | 2.54092383 |
31 | Abnormal gallbladder physiology (HP:0012438) | 2.54092383 |
32 | Missing ribs (HP:0000921) | 2.53206963 |
33 | Distal upper limb amyotrophy (HP:0007149) | 2.53053919 |
34 | Upper limb amyotrophy (HP:0009129) | 2.53053919 |
35 | Renal duplication (HP:0000075) | 2.52193248 |
36 | Arterial tortuosity (HP:0005116) | 2.52090351 |
37 | Adenoma sebaceum (HP:0009720) | 2.48549904 |
38 | Angiofibromas (HP:0010615) | 2.48549904 |
39 | Proximal placement of thumb (HP:0009623) | 2.44420893 |
40 | Wormian bones (HP:0002645) | 2.44026453 |
41 | Increased nuchal translucency (HP:0010880) | 2.43564793 |
42 | Abnormality of the lower motor neuron (HP:0002366) | 2.42672343 |
43 | Abdominal situs inversus (HP:0003363) | 2.42484621 |
44 | Abnormality of abdominal situs (HP:0011620) | 2.42484621 |
45 | Long palpebral fissure (HP:0000637) | 2.41148203 |
46 | Pointed chin (HP:0000307) | 2.39373265 |
47 | Shoulder girdle muscle weakness (HP:0003547) | 2.39202270 |
48 | Pelvic girdle muscle weakness (HP:0003749) | 2.37715984 |
49 | Cerebral aneurysm (HP:0004944) | 2.35363525 |
50 | Abnormality of the distal phalanges of the toes (HP:0010182) | 2.35144163 |
51 | Natal tooth (HP:0000695) | 2.34247971 |
52 | Vascular tortuosity (HP:0004948) | 2.33189614 |
53 | Bowel diverticulosis (HP:0005222) | 2.32227389 |
54 | Protrusio acetabuli (HP:0003179) | 2.31918530 |
55 | Shallow orbits (HP:0000586) | 2.27917635 |
56 | Abnormality of the calcaneus (HP:0008364) | 2.24856015 |
57 | Back pain (HP:0003418) | 2.24184226 |
58 | Increased density of long bones (HP:0006392) | 2.23717143 |
59 | Elbow flexion contracture (HP:0002987) | 2.21605017 |
60 | Mildly elevated creatine phosphokinase (HP:0008180) | 2.20197313 |
61 | Cerebral inclusion bodies (HP:0100314) | 2.16703499 |
62 | Asymmetry of the thorax (HP:0001555) | 2.15559152 |
63 | Short 4th metacarpal (HP:0010044) | 2.15342228 |
64 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 2.15342228 |
65 | Abnormality of dentin (HP:0010299) | 2.14773162 |
66 | Cutaneous melanoma (HP:0012056) | 2.14570741 |
67 | Mitral regurgitation (HP:0001653) | 2.13547559 |
68 | Abnormality of the anterior horn cell (HP:0006802) | 2.13002703 |
69 | Degeneration of anterior horn cells (HP:0002398) | 2.13002703 |
70 | Centrally nucleated skeletal muscle fibers (HP:0003687) | 2.12897910 |
71 | Abnormal number of incisors (HP:0011064) | 2.08177052 |
72 | Neoplasm of the oral cavity (HP:0100649) | 2.07974494 |
73 | Gastrointestinal carcinoma (HP:0002672) | 2.06733374 |
74 | Malignant gastrointestinal tract tumors (HP:0006749) | 2.06733374 |
75 | Abnormality of the musculature of the pelvis (HP:0001469) | 2.02459121 |
76 | Abnormality of the hip-girdle musculature (HP:0001445) | 2.02459121 |
77 | Termporal pattern (HP:0011008) | 2.02065010 |
78 | Insidious onset (HP:0003587) | 2.02065010 |
79 | Resting tremor (HP:0002322) | 2.01195954 |
80 | Biliary tract neoplasm (HP:0100574) | 2.01014928 |
81 | Congenital stationary night blindness (HP:0007642) | 2.00010861 |
82 | Nuclear cataract (HP:0100018) | 1.98247909 |
83 | Esophageal atresia (HP:0002032) | 1.97964368 |
84 | Rhabdomyosarcoma (HP:0002859) | 1.97421601 |
85 | Generalized amyotrophy (HP:0003700) | 1.97237699 |
86 | Flat acetabular roof (HP:0003180) | 1.96657887 |
87 | High pitched voice (HP:0001620) | 1.94176009 |
88 | Wrist flexion contracture (HP:0001239) | 1.93660968 |
89 | Short humerus (HP:0005792) | 1.93074731 |
90 | Basal cell carcinoma (HP:0002671) | 1.92898668 |
91 | Aplasia/hypoplasia of the humerus (HP:0006507) | 1.92591920 |
92 | Fibroma (HP:0010614) | 1.92525836 |
93 | Aortic dissection (HP:0002647) | 1.91612436 |
94 | Blue sclerae (HP:0000592) | 1.90379855 |
95 | Freckling (HP:0001480) | 1.89934075 |
96 | Advanced eruption of teeth (HP:0006288) | 1.89933420 |
97 | Neoplasm of the pancreas (HP:0002894) | 1.87087182 |
98 | Abnormality of the umbilical cord (HP:0010881) | 1.85749617 |
99 | Fibrous tissue neoplasm (HP:0012316) | 1.85017140 |
100 | Neoplasm of striated muscle (HP:0009728) | 1.84398031 |
101 | Neurofibrillary tangles (HP:0002185) | 1.82677318 |
102 | Disproportionate tall stature (HP:0001519) | 1.82581277 |
103 | Reduced subcutaneous adipose tissue (HP:0003758) | 1.82374077 |
104 | Entropion (HP:0000621) | 1.80655321 |
105 | Abnormality of skeletal muscle fiber size (HP:0012084) | 1.80033090 |
106 | Elfin facies (HP:0004428) | 1.78578791 |
107 | Broad thumb (HP:0011304) | 1.78288123 |
108 | Increased variability in muscle fiber diameter (HP:0003557) | 1.77807254 |
109 | Dysmetric saccades (HP:0000641) | 1.77610636 |
110 | Spinal cord compression (HP:0002176) | 1.77102533 |
111 | Bladder diverticulum (HP:0000015) | 1.76840482 |
112 | Hereditary nonpolyposis colorectal carcinoma (HP:0006716) | 1.76822958 |
113 | Ankle contracture (HP:0006466) | 1.75220972 |
114 | Intestinal polyp (HP:0005266) | 1.74456052 |
115 | Cafe-au-lait spot (HP:0000957) | 1.74301121 |
116 | Dilatation of the ascending aorta (HP:0005111) | 1.73668823 |
117 | Trigonocephaly (HP:0000243) | 1.72649245 |
118 | Skull defect (HP:0001362) | 1.72522703 |
119 | Hypopigmentation of the fundus (HP:0007894) | 1.72458387 |
120 | Birth length less than 3rd percentile (HP:0003561) | 1.71859502 |
121 | Intestinal polyposis (HP:0200008) | 1.71158906 |
122 | Breech presentation (HP:0001623) | 1.70951094 |
123 | Insomnia (HP:0100785) | 1.70861630 |
124 | Radial bowing (HP:0002986) | 1.70217611 |
125 | Pterygium (HP:0001059) | 1.69892503 |
126 | Biconcave vertebral bodies (HP:0004586) | 1.69530978 |
127 | Ovarian neoplasm (HP:0100615) | 1.69426182 |
128 | Flat cornea (HP:0007720) | 1.68844672 |
129 | Patellar dislocation (HP:0002999) | 1.68590097 |
130 | Abnormal ossification of hand bones (HP:0005921) | 1.67773178 |
131 | Vertebral arch anomaly (HP:0008438) | 1.66364483 |
132 | Bowed forearm bones (HP:0003956) | 1.65758806 |
133 | Bowing of the arm (HP:0006488) | 1.65758806 |
134 | Abnormality of the acetabulum (HP:0003170) | 1.65590163 |
135 | Uterine neoplasm (HP:0010784) | 1.65540748 |
136 | Genu recurvatum (HP:0002816) | 1.63815208 |
137 | Patellar aplasia (HP:0006443) | 1.63813170 |
138 | Pseudobulbar signs (HP:0002200) | 1.63609644 |
139 | Nail dystrophy (HP:0008404) | 1.63592745 |
140 | Trismus (HP:0000211) | 1.63545029 |
141 | Absent radius (HP:0003974) | 1.62850034 |
142 | Broad phalanges of the hand (HP:0009768) | 1.62490789 |
143 | Ridged nail (HP:0001807) | 1.61916868 |
144 | Atrophy/Degeneration involving motor neurons (HP:0007373) | 1.61202337 |
145 | Syringomyelia (HP:0003396) | 1.60933605 |
146 | Spinal cord lesions (HP:0100561) | 1.60933605 |
147 | Renovascular hypertension (HP:0100817) | 1.60841212 |
148 | Abnormality of the distal phalanx of the thumb (HP:0009617) | 1.60370851 |
149 | Slender long bone (HP:0003100) | 1.60328391 |
150 | Orthostatic hypotension (HP:0001278) | 1.60176466 |
151 | Skin tags (HP:0010609) | 1.59910018 |
152 | Difficulty climbing stairs (HP:0003551) | 1.59498692 |
153 | Absent frontal sinuses (HP:0002688) | 1.59347565 |
154 | Metaphyseal cupping (HP:0003021) | 1.59133718 |
155 | Abnormality of oral frenula (HP:0000190) | 1.59007617 |
156 | Limb-girdle muscle atrophy (HP:0003797) | 1.58755016 |
157 | Mitral valve prolapse (HP:0001634) | 1.58744609 |
158 | Type 1 muscle fiber predominance (HP:0003803) | 1.58414133 |
159 | Overriding aorta (HP:0002623) | 1.58034119 |
160 | Preauricular skin tag (HP:0000384) | 1.58008409 |
161 | Milia (HP:0001056) | 1.57525118 |
162 | Upper limb muscle weakness (HP:0003484) | 1.57370995 |
163 | Megalocornea (HP:0000485) | 1.57063498 |
164 | Cervical subluxation (HP:0003308) | 1.56996370 |
165 | Ankyloglossia (HP:0010296) | 1.56465472 |
166 | Spinal muscular atrophy (HP:0007269) | 1.56398468 |
167 | Upper motor neuron abnormality (HP:0002127) | 1.56186581 |
168 | Aplasia/Hypoplasia of the vertebrae (HP:0008515) | 1.55804499 |
169 | Vertebral hypoplasia (HP:0008417) | 1.55804499 |
170 | Broad distal phalanx of finger (HP:0009836) | 1.55521743 |
171 | Hyperparathyroidism (HP:0000843) | 1.53958985 |
172 | Arnold-Chiari malformation (HP:0002308) | 1.53783818 |
173 | Hammertoe (HP:0001765) | 1.53295509 |
Rank | Gene Set | Z-score |
---|---|---|
1 | NEK1 | 4.05160838 |
2 | PKN2 | 3.90695540 |
3 | EEF2K | 3.82336157 |
4 | CDC7 | 3.35298860 |
5 | TSSK6 | 3.22622169 |
6 | IRAK3 | 3.05563126 |
7 | SMG1 | 2.92490360 |
8 | MST1R | 2.85834577 |
9 | BUB1 | 2.74560628 |
10 | PASK | 2.63465213 |
11 | NME2 | 2.50765715 |
12 | TRIB3 | 2.46831789 |
13 | NEK2 | 2.35143469 |
14 | CDK12 | 2.28342592 |
15 | TTN | 2.23447613 |
16 | SIK1 | 2.12823236 |
17 | WEE1 | 2.08700350 |
18 | EPHA2 | 2.02986708 |
19 | SCYL2 | 1.98806420 |
20 | TESK2 | 1.97957644 |
21 | NTRK1 | 1.96338281 |
22 | ARAF | 1.94450721 |
23 | PRPF4B | 1.93885810 |
24 | RPS6KB2 | 1.91470695 |
25 | PAK4 | 1.81725729 |
26 | ALK | 1.71933155 |
27 | LATS2 | 1.70059143 |
28 | TTK | 1.68374774 |
29 | MOS | 1.66321865 |
30 | TESK1 | 1.65312323 |
31 | LMTK2 | 1.60324022 |
32 | MAP3K10 | 1.57879716 |
33 | ERN1 | 1.57450238 |
34 | MAP3K8 | 1.47643876 |
35 | ERBB4 | 1.40378821 |
36 | FLT3 | 1.39633931 |
37 | TGFBR1 | 1.35155868 |
38 | FGFR1 | 1.34912208 |
39 | PLK3 | 1.32873538 |
40 | PLK1 | 1.26394339 |
41 | KSR2 | 1.26361283 |
42 | ATR | 1.22463033 |
43 | MAP3K13 | 1.19870751 |
44 | FGFR4 | 1.18220843 |
45 | MAP3K9 | 1.14778325 |
46 | RIPK1 | 1.14382288 |
47 | PDGFRA | 1.11623855 |
48 | CHEK1 | 1.11022200 |
49 | PAK6 | 1.10783797 |
50 | LIMK1 | 1.06053784 |
51 | LRRK2 | 1.05689218 |
52 | BMX | 1.05679036 |
53 | AURKB | 1.04258390 |
54 | KSR1 | 1.03278776 |
55 | CDK7 | 0.99392525 |
56 | STK10 | 0.97965756 |
57 | CDK4 | 0.97914193 |
58 | PRKD3 | 0.96807454 |
59 | EPHB1 | 0.96702136 |
60 | BRD4 | 0.95249849 |
61 | MTOR | 0.94747463 |
62 | PTK6 | 0.93027447 |
63 | CDK8 | 0.90894244 |
64 | EPHB2 | 0.89247911 |
65 | AURKA | 0.88790955 |
66 | BRAF | 0.87162614 |
67 | RPS6KA4 | 0.85598286 |
68 | BRSK1 | 0.85140516 |
69 | PAK2 | 0.83340008 |
70 | SIK3 | 0.78920368 |
71 | NEK9 | 0.78639357 |
72 | CDK2 | 0.78481559 |
73 | PAK1 | 0.77306369 |
74 | MKNK1 | 0.75078695 |
75 | EIF2AK1 | 0.73269067 |
76 | PIM2 | 0.71901272 |
77 | AKT2 | 0.70890101 |
78 | CHEK2 | 0.68656399 |
79 | CDK15 | 0.67723269 |
80 | SRPK1 | 0.67582444 |
81 | CDK18 | 0.65144464 |
82 | CDK6 | 0.63295511 |
83 | CDK14 | 0.62607632 |
84 | ATM | 0.61888760 |
85 | MAPKAPK3 | 0.61712480 |
86 | MAPK11 | 0.61710961 |
87 | CDK11A | 0.61343424 |
88 | ICK | 0.59506927 |
89 | BRSK2 | 0.57980170 |
90 | FER | 0.57794519 |
91 | CDK1 | 0.57479728 |
92 | PTK2 | 0.56485780 |
93 | PDK3 | 0.56422038 |
94 | PDK4 | 0.56422038 |
95 | TAOK2 | 0.56051790 |
96 | PBK | 0.56014141 |
97 | DAPK1 | 0.53297799 |
98 | STK38L | 0.53027804 |
99 | CDK9 | 0.52072630 |
100 | CAMKK1 | 0.51722983 |
101 | MINK1 | 0.51153289 |
102 | ILK | 0.49834228 |
103 | CSNK1E | 0.49121851 |
104 | RPS6KA2 | 0.48817554 |
105 | DDR2 | 0.48441413 |
106 | MAP3K3 | 0.48424608 |
107 | VRK2 | 0.46255174 |
108 | PNCK | 0.43828698 |
109 | MAP3K14 | 0.43331696 |
110 | DAPK3 | 0.43166789 |
111 | PRKDC | 0.42975726 |
112 | MAP2K3 | 0.42341548 |
113 | CDC42BPA | 0.42245503 |
114 | CAMK1D | 0.41868205 |
115 | MELK | 0.41244694 |
116 | PDPK1 | 0.40716842 |
117 | CSNK1D | 0.39975361 |
118 | MET | 0.39714234 |
119 | IRAK2 | 0.37650623 |
120 | CAMK2G | 0.37579655 |
121 | LATS1 | 0.37555081 |
122 | PDGFRB | 0.36770997 |
123 | TLK1 | 0.36413996 |
124 | RET | 0.36103670 |
125 | ROCK2 | 0.34523945 |
126 | PRKCI | 0.32697572 |
127 | CSNK2A2 | 0.30797203 |
128 | TYRO3 | 0.30224281 |
129 | STK38 | 0.29588237 |
130 | RAF1 | 0.29536681 |
131 | STK4 | 0.28989670 |
132 | MAPK14 | 0.28712188 |
133 | AKT1 | 0.26069688 |
Rank | Gene Set | Z-score |
---|---|---|
1 | DNA replication_Homo sapiens_hsa03030 | 3.35884919 |
2 | Mismatch repair_Homo sapiens_hsa03430 | 3.02032693 |
3 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 2.96483886 |
4 | RNA transport_Homo sapiens_hsa03013 | 2.66131264 |
5 | Spliceosome_Homo sapiens_hsa03040 | 2.50276839 |
6 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.41442771 |
7 | Cell cycle_Homo sapiens_hsa04110 | 2.31288064 |
8 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.29542352 |
9 | Base excision repair_Homo sapiens_hsa03410 | 1.89939871 |
10 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.77157354 |
11 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.71839802 |
12 | * Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 1.65543463 |
13 | ECM-receptor interaction_Homo sapiens_hsa04512 | 1.59424709 |
14 | * Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.57454743 |
15 | * Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 1.50535143 |
16 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 1.48752944 |
17 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 1.45130894 |
18 | Oocyte meiosis_Homo sapiens_hsa04114 | 1.40986700 |
19 | Other glycan degradation_Homo sapiens_hsa00511 | 1.40600732 |
20 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.37732315 |
21 | Prion diseases_Homo sapiens_hsa05020 | 1.33950014 |
22 | RNA degradation_Homo sapiens_hsa03018 | 1.29386052 |
23 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 1.27085211 |
24 | Homologous recombination_Homo sapiens_hsa03440 | 1.26306797 |
25 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.25372420 |
26 | Hippo signaling pathway_Homo sapiens_hsa04390 | 1.25224929 |
27 | mTOR signaling pathway_Homo sapiens_hsa04150 | 1.24850601 |
28 | * Viral carcinogenesis_Homo sapiens_hsa05203 | 1.23395367 |
29 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.22743859 |
30 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 1.18911996 |
31 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 1.18702399 |
32 | Bladder cancer_Homo sapiens_hsa05219 | 1.15914195 |
33 | Colorectal cancer_Homo sapiens_hsa05210 | 1.13495517 |
34 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.10899348 |
35 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 1.08793175 |
36 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 1.07020393 |
37 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 1.06715404 |
38 | HTLV-I infection_Homo sapiens_hsa05166 | 1.05727945 |
39 | Proteasome_Homo sapiens_hsa03050 | 1.04016551 |
40 | Basal cell carcinoma_Homo sapiens_hsa05217 | 1.03275063 |
41 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 1.03108859 |
42 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 1.01100266 |
43 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.99363322 |
44 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.98766757 |
45 | Adherens junction_Homo sapiens_hsa04520 | 0.98564964 |
46 | Amoebiasis_Homo sapiens_hsa05146 | 0.97911548 |
47 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.97302671 |
48 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.97127873 |
49 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.95964539 |
50 | Alcoholism_Homo sapiens_hsa05034 | 0.95097792 |
51 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.94727291 |
52 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.94673197 |
53 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.94497448 |
54 | Thyroid cancer_Homo sapiens_hsa05216 | 0.93623087 |
55 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.93079100 |
56 | Salmonella infection_Homo sapiens_hsa05132 | 0.91548678 |
57 | RNA polymerase_Homo sapiens_hsa03020 | 0.90778426 |
58 | * Carbon metabolism_Homo sapiens_hsa01200 | 0.89663381 |
59 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.89512996 |
60 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.88647849 |
61 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.88070584 |
62 | Glioma_Homo sapiens_hsa05214 | 0.83816156 |
63 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.83180978 |
64 | Endometrial cancer_Homo sapiens_hsa05213 | 0.82934888 |
65 | Tight junction_Homo sapiens_hsa04530 | 0.82743496 |
66 | Prostate cancer_Homo sapiens_hsa05215 | 0.81369208 |
67 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.80156434 |
68 | Endocytosis_Homo sapiens_hsa04144 | 0.78691698 |
69 | Galactose metabolism_Homo sapiens_hsa00052 | 0.78026101 |
70 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.77903400 |
71 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.77365908 |
72 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.76543363 |
73 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.76297590 |
74 | Melanoma_Homo sapiens_hsa05218 | 0.76030081 |
75 | Focal adhesion_Homo sapiens_hsa04510 | 0.75304767 |
76 | Lysosome_Homo sapiens_hsa04142 | 0.75249392 |
77 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.73244426 |
78 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.72590427 |
79 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.72330541 |
80 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.69457232 |
81 | Legionellosis_Homo sapiens_hsa05134 | 0.69112484 |
82 | Viral myocarditis_Homo sapiens_hsa05416 | 0.68738047 |
83 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.68147457 |
84 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.66868692 |
85 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.66025653 |
86 | Shigellosis_Homo sapiens_hsa05131 | 0.63509506 |
87 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.62476838 |
88 | Pathways in cancer_Homo sapiens_hsa05200 | 0.62459182 |
89 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.62410777 |
90 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.61481479 |
91 | Gap junction_Homo sapiens_hsa04540 | 0.61277821 |
92 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.60760753 |
93 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.60381979 |
94 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.60356115 |
95 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.59588307 |
96 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.59413659 |
97 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.59009862 |
98 | Apoptosis_Homo sapiens_hsa04210 | 0.58318116 |
99 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.56268516 |
100 | Ribosome_Homo sapiens_hsa03010 | 0.55706611 |
101 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.54190509 |
102 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.53941991 |
103 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.53569348 |
104 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.53200911 |
105 | Axon guidance_Homo sapiens_hsa04360 | 0.52145010 |
106 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.51210614 |
107 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.51176930 |
108 | Hepatitis C_Homo sapiens_hsa05160 | 0.50140450 |
109 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.49633587 |
110 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.48300006 |
111 | Phototransduction_Homo sapiens_hsa04744 | 0.47712281 |
112 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.47387648 |
113 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.47377878 |
114 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.45902460 |
115 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.45740772 |
116 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.44865565 |
117 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.44738159 |
118 | Long-term potentiation_Homo sapiens_hsa04720 | 0.44551200 |
119 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.44511568 |
120 | Hepatitis B_Homo sapiens_hsa05161 | 0.44328438 |
121 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.44275104 |
122 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.43844720 |
123 | Lysine degradation_Homo sapiens_hsa00310 | 0.43462794 |
124 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.42755418 |
125 | Melanogenesis_Homo sapiens_hsa04916 | 0.41885309 |
126 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.41671293 |
127 | * Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.40375973 |
128 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.39621925 |